Drug Abuse, Cannabis

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    IntroductionA drug, roughly speaking, is any substance that, when absorbed into the

    body of a living organism, modifies normal physical function. There is no

    single, exact definition, as there are different meanings in drug control law,

    government regulations, medicine, and everyday usage.

    They are made or grown at home by the user or dealer, made or grown in

    internal labs or greenhouses, diverted (stolen or sold on) from valid sources

    such as chemists, or imported - from producer nations such as Colombia or

    from transit countries such as the Netherlands or Spain. Drugs can enter the

    body in many ways. Some ways in which drugs enter the body is by it being

    injected, swallowed, snorted, smoked, etc. In pharmacology, a drug is "a

    chemical substance used in the treatment, cure, prevention, or finding of

    disease or used to otherwise improve physical or mental well-being. Drugs

    may be prescribed for a limited period, or on a regular basis for long-lasting

    disorder. Recreational drugs are chemical substances that affect the central

    nervous system, such as opioids or hallucinogens. They may be used for

    seeming beneficial effects on perception, awareness, personality, and

    behavior. Some drugs can cause addiction and/or habituation.

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    MARIJUANA (Cannabis)

    Loose Marijuana

    Marijuana Leaf

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    What is Marijuana?

    Marijuana is a green, brown, or gray mixture of dried, shredded leaves,

    stems, seeds, and flowers of the hemp plant. You may hear marijuana called

    by street names such as pot, herb, weed, grass, boom, Mary Jane, gangster,

    or chronic. There are more than 200 slang terms for marijuana.

    Cannabis, also known as marijuana (sometimes spelled "marihuana) among

    many other names, refers to any number of preparations of the Cannabis

    plant intended for use as a psychoactive drug. The word marijuana comes

    from the Mexican Spanish word, marihuana. According to the United

    Nations, cannabis "is the most widely used illicit substance in the world."

    The typical herbal form of cannabis consists of the flowers and subtending

    leaves and stalks of mature pistillate of female plants. The adhesive form of

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    the drug is known as hashish (or merely as 'hash'). The major psychoactive

    chemical compound in cannabis is tetrahydrocannabinol (THC). Cannabis

    contains more than 400 different chemical compounds, including at least 60

    other cannabinoids (CBD), and tetrahydrocannabivari (THCV), which can

    result in different effects from those of THC alone.

    HISTORY

    Cannabis is native to Central and South Asia. Evidence of the inhalation of

    cannabis smoke can be found in the 3rd millennium B.C, as indicated by

    burnt cannabis seeds found in a ritual fire at an ancient burial site in present

    day. Romania Cannabis is also known to have been used by the ancient

    Hindus and Nihang Sikhs of India and Nepal for thousands of years.

    Cannabis was also known to the ancient Assyrians, who discovered its

    psychoactive properties through the Aryans. Using it in some religious

    ceremonies, they called it Qumbu (meaning "way to produce smoke"), a

    probable origin of the modern word "cannabis". Cannabis was also

    introduced by the Aryans to the Scythians and Thracians, whose shamans

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    (the kapnobatai"those who walk on smoke/clouds") burned cannabis

    flowers to induce a state of trance. Members of the cult of Dionysus,

    believed to have originated in Thrace (Bulgaria, Greece and Turkey), are

    also thought to have inhaled cannabis smoke.

    In 2003, a leather basket filled with cannabis leaf fragments and seeds were

    found next to a 2,500- to 2,800-year-old mummified shaman in the

    northwestern Xinjiang Uygur Autonomous Region of China.

    Cannabis has an ancient history of ritual use and is found in pharmacological

    cults around the world. Hemp seeds discovered by archaeologists at Pazyryk

    suggest early ceremonial practices like eating by the Scythians occurred

    during the 5th to 2nd century B.C., confirming previous historical reports by

    Herodotus.

    Cannabis use has been found to have occurred as long ago as the 3rd

    millennium BC In modern times the drug has been used for entertaining,

    religious or spiritual, and medicinal purposes. The UN estimated that in 2004

    about 4% of the world's adult population (162 million people) use cannabis

    annually, and about 0.6% (22.5 million) use it on a daily basis. The

    possession, use, or sale of cannabis preparations containing psychoactive

    cannabinoids became illegal in most parts of the world in the early 20th

    century.

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    EFFECTS ON THE BRAIN

    Marijuana interrupts on the central nervous system by attaching the brain's

    neurons and interfering with normal communication between the neurons.

    These nerves respond by shifting their original behavior. For example, if a

    nerve is supposed to assist one in recovering short-term memory,

    cannabinoids receptors make them do the opposite. So if one has to

    remember what he did five minutes ago, after smoking a high dose of

    marijuana, he has trouble. Marijuana plant contains 400 chemicals and 60 of

    them are cannabinoids, which are psychoactive compounds that are

    produced inside the body after cannabis is absorbed or is extorted from the

    cannabis plant. Cannabinoids is an active ingredient of marijuana. The most

    psychoactive cannabinoids chemical in marijuana that has the biggest

    impact on the brain is tetrahydrocannibinol, or THC. THC is the main active

    ingredient in marijuana because it affects the brain by binding to and

    activating specific receptors, known as cannabinoid receptors. "These

    receptors control memory, thought, concentration, time and deepness, and

    matched movement. THC also affects the production, release or re-uptake (a

    regulating mechanism) of various neurotransmitters." Neurotransmitters are

    chemical messenger molecules that carry signals between neurons. Some of

    these affects are personality disturbances, depression and chronic anxiety.

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    Psychiatrists who treat schizophrenic patient advices them to not use this

    drug because marijuana can trigger severe mental disturbances and cause a

    decline. When one's memory is affected by high dose of marijuana, short-

    term memory is the first to be triggered. Marijuana's damage to short-term

    memory occurs because THC alters the way in which information is

    processed by the hippocampus, a brain area responsible for memory

    formation. "One region of the brain that contains a lot of THC receptors is

    the hippocampus, which processes memory." Hippocampus is the part of the

    brain that is important for memory, learning, and the integration of sensory

    experiences with emotions and motivation. It also converts information into

    short-term memory. "Because it is a steroid, THC acts on the hippocampus

    and inhibits memory retrieval." THC also alters the way in which sensory

    information is interpreted. "When THC attaches to receptors in the

    hippocampus, it weakness the short-term memory," and damages the nerve

    cells by creating structural changes to the hippocampus region of the brain.

    When a user has a high dose of marijuana, new information does not record

    into their brain and this may be lost from memory and they are not able to

    retrieve new information for more than a few minutes. There is also a

    decrease in the activity of nerve cells.

    Marijuana also impairs emotions. When smoking marijuana, the user may

    have uncontrollable laughter one minute and paranoia the next. This instant

    change in emotions has to do with the way that THC affects the brain's

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    limbic system. The limbic system is another region of the brain that governs

    one's behavior and emotions. It also "coordinates activities between the

    visceral base-brain and the rest of the nervous system." I am now going to

    use Students B to describe how emotions are affected by marijuana. A

    STUDENT B is an articulate and well-spoken young woman who has a

    troublesome relationship with her best friends which gets her upset and

    tense up. But after she smoked one high dose weed, her body was relaxed

    however, she had trouble formulating her thoughts clearly and would talk in

    pieces and was glad. It has been researched that a person needs to have

    high dose of marijuana would be in the state of euphoria. High dose of

    marijuana is measured as "15mg of THC can cause increased heartrate,

    gross motor disturbances, and can lead to panic attacks." Thankfully,

    Student A did not experience any of these extreme examples

    Research into the effects of long-term cannabis use on the structure of the

    brain has produced unpredictable results. It may be that the effects are too

    delicate for reliable detection by current techniques. A similar challenge

    arises in studies of the effects of chronic marijuana use on brain function.

    Brain imaging studies in chronic users tend to show some constant

    alterations, but their connection to impaired cognitive functioning is far from

    clear. This uncertainty may stem from confounding factors such as other

    drug use, residual drug effects, or withdrawal symptoms in long-term

    chronic users.

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    Scientists have learned a great deal about how THC acts in the brain to

    produce its many effects. When someone smokes marijuana, THC rapidly

    passes from the lungs into the bloodstream, which carries the chemical to

    the brain and other organs throughout the body.

    EFFECTS ON THE HEART

    Marijuana increases heart rate by 20-100 percent shortly after smoking; this effect

    can last up to 3 hours. In one study, it was estimated that marijuana users have a

    4.8-fold increase in the risk of heart attack in the first hour after smoking the drug.

    This may be due to increased heart rate as well as the effects of marijuana on heart

    beats, causing trembles and arrhythmias. This risk may be greater in aging

    populations or in those with cardiac vulnerabilities.

    EFFECTS ON THE LUNGS

    Numerous studies have shown marijuana smoke to contain carcinogens and

    to be an irritant to the lungs. In fact, marijuana smoke contains 50-70

    percent more carcinogenic hydrocarbons than tobacco smoke. Marijuana

    users usually inhale more deeply and hold their breath longer than tobacco

    smokers do, which further increase the lungs' exposure to carcinogenic

    smoke. Marijuana smokers show deregulated growth of epithelial cells in

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    their lung tissue, which could lead to cancer; however, a recent case-

    controlled study found no positive associations between marijuana use and

    lung, upper respiratory, or upper digestive tract cancers.7 Thus, the link

    between marijuana smoking and these cancers remains unconfirmed at this

    time.

    Nonetheless, marijuana smokers can have many of the same respiratory

    problems as tobacco smokers, such as daily cough and composure

    production, more frequent acute chest illness, and a heightened risk of lung

    infections. A study of 450 individuals found that people who smoke

    marijuana frequently but do not smoke tobacco have more health problems

    and miss more days of work than nonsmokers. Many of the extra sick days

    among the marijuana smokers in the study were for respiratory illnesses.

    EFFECTS ON DAILY LIFE

    Research clearly demonstrates that marijuana has the potential to cause problems

    in daily life or make a person's existing problems worse. In one study, heavy

    marijuana abusers reported that the drug reduced several important measures of

    life achievement, including physical and mental health, perceptive abilities, social

    life, and career status. Several studies associate workers' marijuana smoking with

    increased absences, tardiness, accidents, workers' compensation claims, and job

    turnover.

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    MARIJUANA and MENTAL HEALTH

    A number of studies have shown an association between chronic marijuana

    use and increased rates of anxiety, depression, and schizophrenia. Some of

    these studies have shown age at first use to be an important risk factor,

    where early use is a marker of increased vulnerability to later problems.

    However, at this time, it is not clear whether marijuana use causes mental

    problems, worsens them, or reflects an attempt to self-medicate symptoms

    already in existence.

    Chronic marijuana use, especially in a very young person, may also be a

    marker of risk for mental illnesses - including addiction - stemming from

    genetic or environmental vulnerabilities, such as early exposure to stress or

    violence. Currently, the strongest evidence links marijuana use and

    schizophrenia and/or related disorders. High doses of marijuana can produce

    an acute psychotic reaction; in addition, use of the drug may trigger the

    start or relapse of schizophrenia in vulnerable individuals.

    Marijuana Plant with flower

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    CONCLUSION

    While many people consider the effects of marijuana to be fun, marijuana

    does have serious side effects that must not be ignored. Studies have shown

    that marijuana kills brain cells, can lead to depression, loss of sex drive, loss

    of motivation, loss of energy, loss of testosterone and increased irritability.

    These are the long term effects that are difficult to prove.

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    SUBJECT: FAMILY LIFE

    DRUGS

    CANNABIS

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    Bibliography

    1. serendip.brynmawr.edu/exchange/node/1808

    2.wiki.answers.com

    3. wikipedia.org/wiki/Cannabis_(drug)