http://www.bion.no/

Drew Endy

Photo: Steve Jurvetson

Assistant professor in the Department of Bioengineering at Stanford University Synthetic Biologist

Drew Endy

Until 2008: Assistant professor, Department of Biological Engineering, Massachusetts Institute of Technology (MIT)

And co-founder of the open Registry of Standard Biological

Parts led by BioBricks Foundation.

Synthetic Biologist - Assistant professor in the Department of Bioengineering at Stanford University

Co-founder of BioBricks: Engineering of standardized

biological components, devices, and parts

The annual iGEM competition involving

undergraduate students in design of biological

systems by using the BioBrick parts.

Drew Endy

and some of his latest publications….

Title: Gemini, a Bifunctional Enzymatic and Fluorescent Reporter of Gene Expression Author(s): Martin L, Che A, Endy D Source: PLOS ONE   Volume: 4   Issue: 11 Article Number: e7569   Published: NOV 4 2009 Times Cited: 3

Title: Determination of cell fate selection during phage lambda infection Author(s): St-Pierre F, Endy D Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   Volume: 105   Issue: 52   Pages: 20705-20710   Published: DEC 30 2008 Times Cited: 15

Title: TABASCO: A single molecule, base-pair resolved gene expression simulator Author(s): Kosuri S, Kelly JR, Endy D Source: BMC BIOINFORMATICS   Volume: 8 Article Number: 480   Published: DEC 19 2007 Times Cited: 6 Title: Synthetic genomics - Options for governance

Author(s): Garfinkel MS, Endy D, Epstein GL, et al.Source: BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE Volume: 5 Issue: 4 Pages: 359-361 Published: DEC 2007 Times Cited: 6

Title: Decoding NF-kappa B signaling Author(s): Ting AY, Endy D Source: SCIENCE Volume: 298 Issue: 5596 Pages: 1189-1190 Published: NOV 8 2002 Times Cited: 28

Title: BIOMOLECULAR NETWORKS: FROM ANALYSIS TO SYNTHESIS Author(s): Alterovitz G, Blake JA, Dreyfuss JM, et al.Conference Information: Pacific Symposium on Biocomputing, JAN 05-09, 2009 Kohala Coast, HISource: PACIFIC SYMPOSIUM ON BIOCOMPUTING 2009   Pages: 1-3   Published: 2009 Times Cited: 0

Title: Refinement and standardization of synthetic biological parts and devices Author(s): Canton B, Labno A, Endy D Source: NATURE BIOTECHNOLOGY Volume: 26 Issue: 7 Pages: 787-793 Published: JUL 2008 Times Cited: 59

Drew Endy

communicating science...

about…..

BioBricks and The

BioBricks Foundation (BBF) From Wikipedia in December: BioBrick™ standard biological parts are DNA sequences of defined structure and function.

BioBrick™ Assembly Kit

The BioBricks Foundation (BBF)

-BioBrick™ standard DNA parts

-MIT's Registry of Standard Biological Parts

-The International Genetically Engineered Machine (iGEM) competition

-The BBF Technical Standards Working Group

-The BBF Legal Working Group-BioBrick Assembly Kit

Drew Endy with his BioBricks, biological modules of DNA. Photo: Science Photo Library/Scanpix.

Organization of The BioBricks Foundation:

about…..

The BioBricks

Foundation and iGEM

iGEM 2010

Photo: iGEM/Justin Knight

The talk and

debate is

presented by

Doris JordeProfessor Doris Jorde: Vice-Rector of the University of Oslo for the period 2009-2013

Doris Jorde Professor Doris Jorde has been appointed Vice-Rector of the University of Oslo for the period 2009-2013 by the Rector.Doris Jorde obtained a Master of Science degree at the University of California, Berkeley, in 1980, and a PhD in Science Education at the same university in 1984.Since 1984, Professor Jorde has been with the University of Oslo’s Department of Teacher Education and School Development. She also heads the “Rrid-skolen” project (Teaching Scientific Inquiry), and is project manager for the EU project “Mind the Gap”.In 2005 Professor Jorde received the Communication Award at the University of Oslo.

Areas of Responsibility:Leads the Study Committee Contact for the Academic Studies Administration Leads the work on the action plan for internationalisation Responsible for following up teacher training and e-learning

Science Debate-

Events in Vilhelm

Bjerknes’ hus this

fall:

6. oktober kl. 05:40 · Kommenter · Liker

•                                                                            

Det nye realfagsbiblioteket i Vilhelm Bjerknes' hus Bill Bryson sitt foredrag fra 6.september finner du her http://realfagsbiblioteket.exss.no/usr/single.aspx?sid=196. oktober kl. 04:42 · Kommenter · Liker · Vis tilbakemeldinger (1)Skjul tilbakemelding (1) •Anne Vedø liker dette.

Det nye realfagsbiblioteket i Vilhelm Bjerknes' hus Bill Bryson sitt foredrag fra 6.september finner du her http://realfagsbiblioteket.exss.no/usr/single.aspx?sid=19

Science Debate-

Events in Vilhelm Bjerknes’ hus this fall:

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Marcus du SautoyandThe Public

Understanding of

Science

Science Debate-

Events in Vilhelm Bjerknes’ hus this fall:

Science Debate-

Events in Vilhelm Bjerknes’ hus this fall:

Science Debate-

Events in Vilhelm Bjerknes’ hus this fall:

Bioinformatics Users Forum 201012. November in Vilhelm Bjerknes’hus

MLSUiO

Det Nye Realfagsbiblioteket i Vilhelm Bjerknes’ hus og Science debate i Norge i samarbeid med Fritt Ord

Science Debate-

Events in Vilhelm Bjerknes’ hus this fall:

Center for Molecular Biology and Neuroscience (CMBN) Bioinformatics Group og deres samarbeidsprosjekter, om kjernefasilitetet for bioinformatikk, om EMBnet Norway, om PubGene og mye annet på Bioinformatics User Forum 2010.

Science Debate-

Events in Vilhelm Bjerknes’ hus this fall:

Science Debate-

Events in Vilhelm Bjerknes’ hus this fall:

(~3,000 species, based on rRNA sequences)

Please cite the source as:David M. Hillis, Derrick Zwickl, and Robin Gutell, University of Texas(see Science, 2003, 300:1692-1697)

Vi er her!

7th of December

Drew Endy

Syntetisk biologi – skrekkblandet fryd?

about….. Synthetic Biology Synthetic biology is about the design and construction of new biological functions

and systems not found in nature. The disiplin is at the interface between biology and engineering. It is continually evolving..

Synthia

The world’s first synthetic life form - May 2010:

Research group lead by Clyde Hutchinson III, Hamilton Smith og J. Craig Venter - J. Craig Venter Institute (JCVI)A copy of Mycoplasma mycoides cell – replication of the genome after transplantation of synthetic genome into M. capricolum cells

January 2010

June 2010

Ill.: Harry Campbell/ieee spectrum

Syntetisk biologi -

Skrekkblandet fryd

Debatten….

Sissel Rogne

Photo: VG

Director of The Norwegian Biotechnology Advisory Board (Bioteknologinemnda)

Kulseth, M.A., Krajci, P., Myklebost, O., Rogne, S. 1995

Cloning and characterization of two forms of bovine

polymeric immunoglobulin receptor cDNA. DNA and

Cell Biology 14 (3), pp. 251-256

Sissel Rogne

Professor in biotechnology, Department of Ecology and Natural Resource Management, Norwegian University of Life Sciences (UMB)

Director of The Norwegian Biotechnology Advisory Board (Bioteknologinemnda)

Thematic Bulletin from The Norwegian Biotechnology Advisory Board regarding synthetic biology: 08–2010, www.bion.no

Foss, G.S., Rogne, S. 2007 When gene medication is also genetic modification - Regulating DNA treatment Vaccine 25 (30 SPEC. ISS.), pp. 5613-5618

Foss, G.S., Rogne, S. 2003 Gene medication or genetic modification? The devil is in the details Nature Biotechnology 21 (11), pp. 1280-1281

Rogne, S.G., Konglund, A., Meling, T.R., Scheie, D., Johannesen, T.B., Rønning, P., Helseth, E. 2009

Intracranial tumor surgery in patients >70 years of age: Is clinical practice worthwhile or futile?

Acta Neurologica Scandinavica 120 (5), pp. 288-294 . v

Worth knowing about synthetic biology (in norwegian)

Bioteknologinemnda er et frittstående, rådgivende organ som er oppnevnt av Regjeringen og hjemlet i lov om framstilling og bruk av genmodifiserte organismer (Genteknologiloven) og i lov om humanmedisinsk bruk av bioteknologi m. m. (Bioteknologiloven). Bioteknologinemnda er en høringsinstans for norske myndigheter i forbindelse med saker som vedrører moderne bioteknologi. Bioteknologinemnda skal bidra med informasjon til publikum og forvaltningen, og fremme debatt omkring de etiske og samfunnsmessige konsekvensene ved bruk av moderne bioteknologi.

Bioteknologinemnda er oppnevnt av regjeringen, første gang i 1991, så i 1998, 2000, 2004 og sist i august 2008.

Den nåværende Bioteknologinemnda er oppnevnt for en fireårsperiode.

Bioteknologinemnda har 21 medlemmer og observatører fra sju departmenter.

Bioteknologinemnda arrangerer hvert år minst fire åpne møter om aktuelle temaer innen moderne bioteknologi. Tidligere utga

Bioteknologinemnda rapporter med gjengivelse av foredragene fra møtene. Fra 2010 blir video fra møtene lagt på nett. Bioteknologinemnda gir også ut debatthefter, temaark og tidsskriftet GENialt, som kommer ut fire ganger i året, og har et opplag på 9000 eksemplarer per utgave. Alle

Bioteknologinemndas publikasjoner er gratis.

Inger Sandlie

Professor at the Department of Molecular Biosciences (IMBV), UiO

Assistant Director, Centre for Immune Regulation, IMBV, UiO

Inger SandlieAssistant Director, Centre for Immune Regulation, IMBV, UiO

Professor at the Department of Molecular Biosciences (IMBV), UiO

Lunde, E., Løset, G.T., Bogen, B., Sandlie, I. 2010 Stabilizing mutations increase secretion of functional soluble

TCR-Ig fusion proteins BMC Biotechnology 10, art. no. 61

Title: ACTIVATION OF COMPLEMENT BY AN IGG MOLECULE WITHOUT A GENETIC HINGE Author(s): BREKKE OH, MICHAELSEN TE, SANDIN R, et al.Source: NATURE Volume: 363 Issue: 6430 Pages: 628-630 Published: JUN 17 1993 Times Cited: 31

Andersen, J.T., Daba, M.B., Sandlie, I. 2010 FcRn binding properties of an abnormal truncated analbuminemic albumin variant Clinical Biochemistry 43 (4-5), pp. 367-372

Brekke, O.H., Sandlie, I. 2003 Therapeutic antibodies for human diseases at

the dawn of the twenty-first century

Nature Reviews Drug Discovery 2 (1), pp. 52-62Jung, S.T., Reddy, S.T., Kang, T.H., Borrok, M.J., Sandlie, I.,

Tucker, P.W., Georgiou, G. 2010

Aglycosylated IgG variants expressed in bacteria that

selectively bind FcγRI potentiate tumor cell killing by

monocyte-dendritic cells

Proceedings of the National Academy of Sciences of the

United States of America 107 (2), pp. 604-609

Centre for Immune Regulation (CIR) The scientific goal of the centre is to identify mechanisms of immune dysregulation that contribute to autoimmune disease and allergy.

Erik Tunstad

Erik TunstadScience journalistProducer (NRK)Disseminator WriterBiologist, entomologist

forskning. no

Scientific editor,

2002-2008

Assistant Professor, Vestfold University College

Darwins teori : evolusjon gjennom 400 år / Erik Tunstad

Year: 2009

.

Kåre Verpe

The Confederation of Norwegian Enterprise (NHO)

Media AdviserSpecial AdviserInformation worker and journalistNRKMorgenbladetDagbladet

chair of debate

session

Synthia

The world’s first synthetic life form - May 2010:

Research group lead by Clyde Hutchinson III, Hamilton Smith og J. Craig Venter - J. Craig Venter Institute (JCVI)A copy of Mycoplasma mycoides cell – replication of the genome after transplantation of synthetic genome into M. capricolum cells

Biologien møter sitt ”Frankensteins øyeblikk”[Teknologirådet, 17.11.2009]

”Biology is approaching its Frankenstein moment – the creation of life from scratch. Sometime within the next few months, scientists

are likely to announce that they have made a living cell from chemical ingredients that can be bought off the shelf.”

Financial Times, august 2009

Ill.:iStockPhotoHentet på websidene til Teknologirådet. Fine celler!

Det nye Realfagsbiblioteket

The new Science Library

in Vilhelm Bjerknes’ hus

and

Science Debate in Norway ,

supported by Fritt Ord

VILHELM BJERKNES’ HUS

Get Real

Commitment to Science

for students and employees at

University of Oslo

– et sted å legge grunnlag for ny forskning, fortsette læringen, bli inspirert, møte venner, kollegaer og foreleser.

Who?

The norwegian scientist Vilhelm Bjerknes (1862-1951) is regarded as one of the founders of meteorology.

He was also a prominent scientist in physics and geophysics.

The New Science Library in Vilhelm Bjerknes’ husand

Science debate in Norway- a cooperation with Fritt Ord

On FacebookDet Nye

Realfagsbiblioteket also

in 2011

………..something to read during your Christmas holiday…

Synthetic biology –

Literature ….

Synthetic biology –

books to read

continued….

0, 1, 1, 2, 3, 5, 8, 13, 21, 34, 55, 89, 144,……

” There is grandeur in this view of life, with its several powers, having been originally breathed into a few forms or into one; and that, whilst this planet has gone cycling on according to the fixed law of gravity, from so simple a beginning endless forms most beautiful and most wonderful have been, and are being, evolved.”