Dr. Showket Hussain, Scientist -D at ICMR National...

Dr. Showket Hussain, Scientist- D (Assistant Director) Division of Molecular Oncology & Head Molecular Diagnostics National Institute of Cancer Prevention & Research, Indian Council of Medical Research (NICPR- ICMR), Department of Health Research, Ministry of Health & Family Welfare, Govt of India, I-7, Sector-39, NOIDA - 201301, INDIA

+91-120-2446934 +91-120-2446911

[email protected], [email protected];

[email protected],

Dr. Showket is extensively working in India on Human Papillomavirus (HPV) research. His major areas of

research interest at present are transcriptional regulation of viral oncogene expression, cancer drug

discovery, micro RNA research, cancer signaling pathways epigenetics and immunotherapeutic. He has

several National and International grants on common cancers prevalent in India. He has also received

serval awards and is lead editor and reviewer of several International journals. Dr. Showket is mentoring

PhD, post-doctoral, MD and MS students and offers internships to young and curious minds (graduate &

post graduate students) so that they can learn the basics of research and are motivated to take it up further

as their careers.

Major scientific Achievements

Impact and Perception of Human Papillomavirus infection, Cervical Cancer and HPV

Vaccination in North Indian Population. The study demonstrated the level of awareness

and education among college students and their parents; and how these impacts vaccination

program in India. (PLoS One. 2014) (IF: 3).

Plausible role of Notch signalling pathway along with synergistic effect of HPV in

regulating/ development and proliferation of cervical cancer through the deregulation of

Notch Proteins and its ligand Jagged- 1. The study shows correlation between JAG1 and

Dr. Showket Hussain, Scientist- D at ICMR- National Institute of Cancer Prevention

and Research (ICMR-NICPR) and has made outstanding contributions in the field of

Cancer Research, Tumor Virology and cancer molecular epidemiology. He has done

his doctorate from ICMR based laboratory ICMR-NICPR (Formerly ICPO) and post

doctorate from prestigious cancer institute MD Anderson Cancer Centre Houston Texas,

U.S.A. During the last 5 years of his research career he has published more than 70 research papers including

book chapters in reputed international journals and distinguished himself as a renowned molecular oncologist.

mailto:[email protected]



HPV in cervical cancer. In addition to that the study also shows the clinical utility of

NOTCH proteins which may be used as predictable biomarkers in diagnosing different

histological sub-types of HPV associated cervical cancer. (PLoS One. 2014) (IF: 3),

(Nature Publications: Scientific Reports 2018), (IF: 4).

We developed a cost effective DNA based vaccine construct of immunogenic potential

against HPV-16 specific variant (Nature Publications: Scientific Reports 2015). (IF: 4).

We showed two significant variants H78Y and L83V are affecting the two important amino

acid stretches of E6 protien (16-60 and 76-94) which can be targeted to control cervical

cancer in future for the development of HPV-16 vaccine. (Journal of Virological

Methods. 2015)

Discovered novel MicroRNAs (miRNAs) signatures in HPV-mediated cervical

carcinogenesis in Indian women (Tumour Biol. 2015). (IF: 4).

Showed for the first time the incidence of HPV infection in prostate cancer in Indian

population and strengthens the hypothesis that HPV infection could be one of the co- factor

associated with progression of prostate cancer [Nature Publications: Scientific Reports

2015]. (IF: 4).

Highlighted the role of personalized physical activity in improving the quality of life for

breast cancer patients (Frontiers in Oncology, 2017). (IF: 4).

Highlighted the importance of global overview of mutational profiles in predisposition to

gall bladder and the research gaps, future prospects for better management of GBC

(Mutation Research Reviews, 2018) (IF: 5).

Demonstrated for the first time role of tumor suppressor PML expression in different

pathological grades of cervical cancer and its synergism between HPV infection. In

addition, differential expression pattern of PML in cervical precancer (CINI) as compared

to CINII and CINIII precancerous lesions was observed indicating its potential early

biomarker for cervical carcinogenesis (Gynecol Oncol. Dec 2013).

Contributed in establishing ICPO-ICMR as a WHO referral Center for HPV serology for

whole South-East Asia.

Showed how gene environment interactions influence (Molecular Carcinogenesis,

50(7):487-98, 2011) and Methylation-mediated gene silencing of suppressor of cytokine

signaling-1 (SOCS-1) gene in the development of esophageal cancer in Kashmir Valley.

Journal of Receptors & Signal Transduction Research. 2011 Apr;31(2):147-56.

Demonstrated the genetic and epigenetic modifications of KRAS gene mutation,

RASSF1A, FHIT and MGMT genes methylation could be used as diagnostic adjunct for

colorectal tumorigenesis and may help in improving the overall approach towards this

disease (PLoS One. 2013).

Developed a Non Invasive method using urine samples for detection of human

papillomaviruses (HPVs). Journal of Medical Virology. 2012 Feb;84(2):298-305.

Showed for the first time dysregulation of AP-1 activity and differential expression of AP-

1 family of proteins in relation to HPV infection and consumption of sodium-bicarbonate-

brewed hot salted tea which is very widely consumed by majority of people in snow-capped

Kashmir Valley. Overall the study demonstrates a pivotal role of AP-1 in esophageal

carcinogenesis and may have direct bearing on the treatment outcome. (BMC Cancer,

2009 9: 329, 1-13).

Showed for the first time an aberrant promoter methylation of p16 gene and loss of its

expression which was found to be strongly associated with severity of esophageal lesion.

Further data demonstrated that consumption of bicarbonate-containing hot salted tea which

is a most favorite drink commonly consumed by Kashmiri people is found to be one of the

high risk factors associated with esophageal carcinogenesis. (Mol Cell Biochem,

2009:332; 51-58).

Developed a cost effective technology for easy transportation and simultaneous detection

and application of a multiplex by PCR for all human papillomaviruses (HPVs) from paper

smear. Journal of Medical Microbiology. 2010 Nov;59(Pt 11):1303-10

Showed correlation of promoter hyper methylation of FHIT and RASSF1A genes with

clinical stage and histological grading of cervical carcinoma in Indian women

(Biomarkers, 2008, 13 (6): 597-606). In addition, identified a novel point mutation in

substrate-binding domain of FHIT and showed by computational modeling that it may

generate catalytically inactive protein with loss of tumor suppressor activity ( Mol Cell

Biochem, 2010, Feb, 335(1-2): 53-58).

Showed an association of total homocysteine levels with the risk of developing carcinoma

of the uterine cervix. This association is independent of MTHFR gene polymorphism.

(Biomarkers 2010, Feb., 15(1), 61-68).

Showed elimination of High-Risk Human Papillomavirus Type HPV16 Infection by

‘Praneem’ Polyherbal Tablet in Women with Early Cervical Intraepithelial Lesions. (J

Cancer Res Clin Oncol, 2009 Dec; 135(12):1701-9).

Technologies developed:

Developed a Non Invasive method using urine samples for detection of human

papillomaviruses (HPVs).

Contributed in establishing ICPO-ICMR as a WHO referral Center for HPV serology for

whole South-East Asia.

Developed a cost effective technology for easy transportation and simultaneous detection

and application of a multiplex by PCR for all human papillomaviruses (HPVs) from paper

smear.

List of publications: (N=78)

S.No

.

Name of the Journal/book Impact

Factor

1 Nazir S., Kumar R., Afroze D., Rasool I., Bondhopadhyay B., Singh A.,

Tripathi R., Singh N., Khan A.,Tanwar P., Agrawal U., Mehrotra R., Hussain

S**. Differential expression of Ets-1 in breast cancer among Indian population.

Journal of Cellular Biochemistry. (Accepted 2019; in press )

3.44

2 Hussain S**, Singh A., Nazir S., Tulsyan S., Khan A., Kumar R., Bashir N.,

Tanwar P., Mehrotra R. Cancer Drug Resistance: A Fleet to Conquer. Journal

of Cellular Biochemistry. (Accepted 2019; in press )

3.44

3 Rasool I., Afroze D., Wani K.A., Yasin S.B., Yousuf A., Hussain S., et al.

Altered expression of survivin and its splice variants ∆Ex3 and 2B contributes

to disease development in breast cancer. Meta Gene. 2019;19:168-73.

1.27

4 Kumar R., Tanwar P., Singh A.R., Hussain S., Rath G.K. Impact of HPV on

the Pathobiology of Cancers. The Gulf Journal of Oncology. (Accepted

2019; in press )

0.32

5 Akhter N., Alzahrani F., Dar S., Wahid M., Sattar R.S., Hussain S., Haque S.,

Ansari S., Jawed A., Mandal R., Shaia A., Alharbi R., Husain S.A. AA

genotype of Cyclin D1 G870A polymorphism increases breast cancer risk:

Findings of a case control study and meta-analysis. Journal of Cellular

Biochemistry. (Accepted 2019; in press )

3.44

6 Tripathi R., Rath G., Sharma V., Hussain S., Sharma S., Bharadwaj M., et al.

HES1 Protein Modulates Human Papillomavirus-Mediated Carcinoma of the

Uterine Cervix. Journal of global oncology. 2019:5(5):1-10.

7 Mehrotra R., Tulsyan S., Hussain S., Mittal B., Saluja S.S., Singh S., Tanwar

P., Javle M., Hassan M., Pant S., Aretxabala X.E., Sirohi S., Rajaraman P.,

Kaur T., Rath GK. Genetic landscape of Gall bladder Cancer: Global overview.

Mutation Research - Reviews. 2018,778:61-71

5.49

8 Tripathi R.,Rath G., Hussain S., Jawanjal P., Bandil K, Sharma V., Bharadwaj

M., Mehrotra R. Jagged-1 induced molecular alterations in HPV associated

invasive squamous cell and adenocarcinoma of the human uterine cervix.

Scientific reports. 2018, 8(1):9359.

4.122

9 Lohani M., Dhasmana A., Haque S., Dar S.A., Jawed A, Wahid M., Mandal

R.K., Akhter N., Farasani A., Hobani Y.H., Singh A., Hussain S. Niacin

deficiency modulates genes involved in cancer: Are smokers at higher risk.

Journal of cellular biochemistry. 2018,1-11

3.446

10 Rasool I., Afroze D., Wani K.A., Yousuf A., Bhat I.A., Rah B., Nazir S.U.,

Hussain S., Dubey S. Role of the Functional Polymorphism of Survivin Gene

(-31G/C) and Risk of Breast Cancer in a North Indian Population. Clinical

breast cancer. 2018, 18(4):e671-e676.

2.703

11 Zaidi S., Hussain S**, Verma S., Veqar Z., Khan A., Nazir S.U., Singh N.,

Moiz J.A., Tanwar P., Srivastava A. Efficacy of Complementary Therapies in

the Quality of Life of Breast Cancer Survivors. Frontiers in oncology.

2017:7:326.

6.41

12 Singh S., Desai R., Modi M., Hussain S. Exploring Laser-Induced Breakdown

Spectroscopy as a Potential Tool in Mohs Micrography: A Mini Review.

Cureus. 2017, 9(11):e1842.

1.5

13 Singh S., Hussain S., Badaya S. Prospects of cytological cervical cancer

screening in India: Exploring adjuvant approaches. Journal of cancer

research and therapeutics. 2017, 13(3):389-391.

0.842

14 Singh S., Hussain S., Badaya S. Cervical cancer screening in rural India:

Cutting on manpower crisis. Journal of Cancer Policy. 2017, 13:81–82 0.762

15 Kumar A., Hussain S., Singh A., Kaul R., Kaul A., Prabhas R., Srivastava

S.K., Goel N., Narang V.K. Protein Kinase C Zeta Inhibitors: A New Hope

For Controlling Maternal Intrauterine Infection Induced Premature Birth. Int.

J Adv Res. 2017 5(5), 465-4774

16 Singh N., Hussain S**, Sharma U., Suri V., Nijhawan R., Bharadwaj M., Sobti

R.C. The protective role of the -1306C>T functional polymorphism in matrix

metalloproteinase-2 gene is associated with cervical cancer: implication of

human papillomavirus infection. Tumour Biology. 2016, 37(4):5295-5303.

3.65

17 Sharma S., Hussain S., Soni K., Singhal P., Tripathi R., Ramachandran V.G.,

Sharma S., Das S., Pillai B., Bharadwaj M. Novel MicroRNA signatures in

HPV-mediated cervical carcinogenesis in Indian women. Tumour biology.

2016, 37(4):4585-4595.

3.605

18 Bandil K., Singhal P., Sharma U., Hussain S., Basu S., Parashari A., Singh V.,

Sehgal A., Shivam A., Ahuja P et al. Impacts of TNF-LTA SNPs/Haplotypes

and Lifestyle Factors on Oral Carcinoma in an Indian Population. Molecular

diagnosis & therapy. 2016, 20(5):469-480.

2.716

19 Singhal P., Sharma U., Hussain S., Nag A., Bharadwaj M. Identification of

genetic variants in TNF receptor 2 which are associated with the development

of cervical carcinoma. Biomarkers. 2016, 21(7):665-672.

2.016

20 Kumar A., Hussain S*, Sharma G., Mehrotra R., Gissmann L., Das B.C.,

Bharadwaj M. Identification and validation of immunogenic potential of India

specific HPV-16 variant constructs: In-silico & in-vivo insight to vaccine

development. Scientific reports. 2015, 5:15751.

4.122

21 Kumar A., Hussain S., Yadav I.S., Gissmann L., Natarajan K., Das B.C.,

Bharadwaj M. Identification of human papillomavirus-16 E6 variation in

cervical cancer and their impact on T and B cell epitopes. Journal of

virological methods. 2015, 218:51-58.

1.693

22 Singh N., Hussain S., Kakkar N., Singh S.K., Sobti R.C., Bharadwaj M.

Implication of high risk human papillomavirus HR-HPV infection in prostate

cancer in Indian population-a pioneering case-control analysis. Scientific

reports. 2015, 5:7822.

4.122

23 Kumar A., Yadav I.S., Hussain S., Das B.C., Bharadwaj M. Identification of

immunotherapeutic epitope of E5 protein of human papillomavirus-16: An in

silico approach. Biologicals. 2015, 43(5):344-348.

1.209

24 Sinha R., Doval D.C., Hussain S., Kumar K., Singh S., Basir S.F., Bharadwaj

M. Lifestyle and Sporadic Colorectal Cancer in India. Asian Pacific journal

of cancer prevention. 2015, 16(17):7683-7688.

1.5

25 Singhal P., Kumar A., Hussain S., Nag A., Bharadwaj M. NFKB1/NFKBIa

polymorphisms are associated with the progression of cervical carcinoma in

HPV-infected postmenopausal women from rural area. Tumour Biology.

2015, 36(8):6265-6276.

3.65

26 Singhal P., Kumar A., Bharadwaj S., Hussain S., Bharadwaj M. Association

of IL-10 GTC haplotype with serum level and HPV infection in the

development of cervical carcinoma. Tumour Biology. 2015, 36(4):2287-2298.

3.65

27 Sharma V., Chandra S.S., Hussain S., Bharadwaj M., Ramachandran V.G.,

Mehrotra R., Khan M.A. Impact of Oral Contraceptives and Smoking on the

Susceptibility of Reproductive Tract Infections (RTIS) in Immunosuppressed

Women: A Hospital Based Study. Int.J.Curr.Microbiol.App.Sci. (2015)

4(12): 363-374.

4.183

28 Singh S., Badaya S., Hussain S. An urgent need to re-strategize loss to follow

up in cervical cancer screening program in India. Journal of Cancer Policy.

Vol. 6, December 2015, 23–24 .

2.09

29 Hussain S., Nasare V., Kumari M., Sharma S., Khan M.A., Das B.C.,

Bharadwaj M. Perception of human papillomavirus infection, cervical cancer

and HPV vaccination in North Indian population. PloS one. 2014,

9(11):e112861.

2.766

30 Hussain S, Sharma U, Bharadwaj M and Mehrotra.R Worthwhileness of Gene

Profiling in Oral cancer. Cancer News. February 18-20, 2014.

31 Tripathi R, Rath G., Jawanjal P, Sharma S, Singhal P, Bhambhani S, Hussain

S, Bharadwaj M. Clinical impact of de-regulated Notch-1 and Notch-3 in the

development and progression of HPV-associated different histological

subtypes of precancerous and cancerous lesions of human uterine cervix. PloS

one. 2014, 9(6):e98642.2):193-199.

2.766

32 Kohaar I., Hussain S*, Kumar A., Singhal P., Choudhury S.R., Das B.C.,

Bharadwaj M. Impact of Haplotype TNF-LTA Locus with Susceptibility to

Cervical Cancer in Indian Population. Obstetrics & Gynecology: An

International Journal. 2014(831817)

5.1

33 Verma G., Hussain S., Singh S.M., Das B.C., Bharti A. C. Transcriptional

Control of Human Papillomavirus in Oncogenic Transformation: Roadmap for

Future Anti-cancer Therapeutics. Perspectives in Cytology and Genetics.

(2014)

0.61

34 Sharma V, Sonkar S.C, Hussain S, Sharma S, Singhal P, Saluja D,

Ramachandran V.G, Bharadwaj M. The burden and risk factors of Multiple

Reproductive Tract Infections among HIV-seropositive women in North

India.(2014)

2.7

35 Bharadwaj M., Hussain S., Tripathi R., Singh N., Mehrotra R. Human

Papillomavirus (HPV): Diagnosis and Treatment.Animal Biotechnology:

Models in Discovery and Translation.(Edited by Ashish Verma and Anchal

Singh). Book chapter 6, pp 95-120, 2014. Publisher Academic Press

(Elsevier).

Book

Chapter

36 Bharadwaj M., Roy G., Dutta K., Misbah M., Husain M., Hussain S. Tackling

hepatitis B virus-associated hepatocellular carcinoma - the future is now.

Cancer Metastasis Rev. 2013,32(1-2): 229-268.

7.25

37 Singh N., Sobti R.C., Suri V., Nijhawan R., Sharma S., Das B.C., Bharadwaj

M., Hussain S**. Downregulation of tumor suppressor gene PML in uterine

cervical carcinogenesis: impact of human papillomavirus infection (HPV).

Gynecol Oncol. 2013,128(3): 420-426.

5.7

38 Singhal P., Hussain S., Thakur N., Batra S., Salhan S., Bhambani S.,

Bharadwaj M. Association of MDM2 and p53 polymorphisms with the

advancement of cervical carcinoma. DNA Cell Biol. 2013,32(1): 19-27.

1.58

39 Bharadwaj M., Hussain S., Chapter name: HPV Vaccine, Gynecological

Cytopathology cervix with clinical aspects 3rd edition (Mehta Publisher) Edited

by: Suresh Bhambani, 2013.

Book

Chapter

40 Sinha R., Hussain S., Mehrotra R., Kumar R. S., Kumar K., Pande P., Doval

D. C., Basir S. F., Bharadwaj M. Kras gene mutation and RASSF1A, FHIT

and MGMT gene promoter hypermethylation: indicators of tumor staging and

metastasis in adenocarcinomatous sporadic colorectal cancer in Indian

population. PLoS One. 2014, 8(4): e60142.

4.49

41 Hussain S., Bharadwaj M., Nasare V., Kumari M., Sharma S., Hedau S., Das

B.C. Human papillomavirus infection among young adolescents in India:

impact of vaccination. J Med Virol. 2012, 84(2): 298-305.

2.3

42 Thakur N., Hussain S., Nasare V., Das B. C., Basir S. F., Bharadwaj M.

Association analysis of p16 (CDKN2A) and RB1 polymorphisms with

susceptibility to cervical cancer in Indian population. 2012 Mol Biol Rep.

2012,39(1): 407-414.

2.02

43 Bharadwaj M., Hussain S., Thakur N. Genetic alterations in Human Cancers:

Translation of microRNAs (miRNAs) into clinical application. Journal of

Carcinogenesis, 2012, 11: S1

2.318

44 Sharma S., Hussain S., Bharadwaj M. Evaluation of SNPs (-572 and - in IL-

6 gene in progression of cervical carcinogenesis. Journal of Carcinogenesis.

2012, 11:S1

2.318

45 Tripathi R, Rath G., Jawanjal P., Sharma S., Hussain S., Bhardwaj M.

Association between Notch-1 protein and HPV associated Invasive

Squamous Carcinoma of human cervix. Journal of Cancer Research and

Therapeutics. 2012, (8) S1

0.5

46 Thakur N., Shrivastava R., Hussain S., Basir S.F., Bharadwaj M. Evaluation

of Functional Relevance of Rare Variant of Cyclin D1 (CCND1) in Cervical

Carcinogenesis. Journal of Carcinogenesis. 2012, 11:S1

2.318

47 Singhal P., Hussain S., Thakur N., Nag A., Bharadwaj M. Evaluation of

NFkB1-94 Insertion/Deletion Promoter Polymorphism and its functional effect

in cervical cancer, Journal of Carcinogenesis. 2012, 11: S 1

2.318

48 Kumar A., Hussain S., Singhal P., Sharma S., Das B.C., Bharadwaj M.

Evaluation of Toll Like Receptors (TLR) 9 Polymorphism in Cancer of Uterine

Cervix in North Indian Population. Journal of Carcinogenesis, 2012,11:S 1

2.215

49 Bandi K., Hussain S., Tripathi R., Nagarjun Rao H.T., Sarda A. K,

Bharadwaj M. Immunohistochemical evaluation of α and β Estrogen receptors

in Prostate Carcinoma. Journal of Carcinogenesis. 2012,11:S 1

2.215

50 Roy G., Hussain S.,Sharma U., Misbah M., Gupta S., Husain M., Bharadwaj

M. Association of TGF-β1 promoter polymorphisms in Hepatitis B Virus

mediated Hepatocellular Carcinoma in Indian population, Journal of

Carcinogenesis. 2012,11:S 1

2.215

51 Sharma V., Kumari S., Sharma S., Hussain S., Malik S., Bharadwaj M.

Identification of Reproductive Tract Infections (RTI) in Human

Immunodeficiency Virus (HIV) positive women in India. Journal of

Carcinogenesis. 2012,11:S 1

2.215

52 Tripathi R., Rath G., Sharma S., Singhal P., Hussain S, Jawanjal P., Bhardwaj

M. Alterations of Jagged-1 protein in Invasive squamous carcinoma of human

cervix: Indian scenario. Journal of Carcinogenesis. 2012,11:S 1

2.215

53 Singh N., Hussain S., Bharadwaj M., Kakkar N., Singh S. K., Sobti R. C.

"Overexpression of signal transducer and activator of transcription (STAT-3

and STAT-5) transcription factors and alteration of suppressor of cytokine

signaling (SOCS-1) protein in prostate cancer. 2012, J Recept Signal

Transduct Res. 32(6): 321-327.

0.67

54 Bharadwaj M., Hussain S., Thakur N. Genetic alterations in Human Cancers:

Translation of miroRNAs (miRNAs) into clinical application. Journal of

Carcinogenesis, Volume 11, S 1, 2012.

2.318

55 Sobti RC., Singh N., Hussain S., Suri V., Nijhawan R., Bharti A.C., Bharadwaj

M., Das B.C. Aberrant promoter methylation and loss of suppressor of cytokine

signalling-1 gene expression in the development of uterine cervical

carcinogenesis. Cell Oncol (Dordr). 2011, 34(6): 533-543.

4.09

56 Dwivedi V., Shrivastava R., Hussain S., Ganguly C., Bharadwaj M.

Comparative anticancer potential of clove (Syzygium aromaticum)--an Indian

spice--against cancer cell lines of various anatomical origin. Asian Pac J

Cancer Prev. 2011,12(8): 1989-1993.

1.5

57 Dwivedi V., Shrivastava R., Hussain S. , Ganguly C. Bharadwaj M. Cytotoxic

potential of Indian spices (extracts) against esophageal squamous carcinoma

cells. Asian Pac J Cancer Prev. 2011,12(8): 2069-2073.

1.5

58 Hedau S., Kumar U.,Hussain S., Shukla S., Pande S., Jain N., Tyagi A.,

Deshpande T., Bhat D., Mir M. M., Chakraborty S., Singh Y. M., Kumar R.,

Somasundaram K., Bharti A. C., Das B. C. Breast cancer and human

papillomavirus infection: no evidence of HPV etiology of breast cancer in

Indian women. BMC Cancer. 2011,11: 27.

3.2

59 Hussain S., Thakur Y. M. N., Salam I., Singh N., Mir M. M., Bhat M. A.,

Siddiqi M. A., Das B. C., Bharadwaj M. Association of cyclin D1 gene

polymorphisms with risk of esophageal squamous cell carcinoma in Kashmir

Valley: a high risk area. Mol Carcinogenesis. 2011,50(7): 487-498.

3.951

60 Hussain S, Bharti A.C., Salam I., Bhat M.A., Mir M.M., Hedau S., Siddiqi

M.A., Basir S.F., Das B.C.Methylation-mediated gene silencing of suppressor

of cytokine signaling-1 (SOCS-1) gene in esophageal squamous cell carcinoma

patients of Kashmir valley. J Recept Signal Transduct Res. 2011,31(2): 147-

156.

0.67

61 Hussain S.,Singh N., Salam I., Bhat M.A., Kakkar N , Mir M.M, Siddiqi

M.A., Basir S.F, Bharti A.C., Bharadwaj M., Das B.C. Transcription factor

NF-kB in esophageal squamous cell carcinoma: Alterations in activity and

expression during Human Papillomavirus infection. Cancer Research.

2011,71:2722;

7.8

62 Singh N, Hussain S., Suri V., Bharadwaj M., Das B.C., Sobti R.C., Aberrant

expression of transcription factors STAT-3 and STAT-5 and their

epigenetic control by SOCS-1 gene: The STAT signaling Crosstalk in HPV

coupled cervical carcinogenesis. Cancer Research. 2011, 71:2719

7.88

63 Neyaz M. K., Hussain S*. , Hassan M. I., Das B. C., Hussain S. A., Bharadwaj

M. Novel missense mutation in FHIT gene: interpreting the effect in HPV-

mediated cervical cancer in Indian women. Mol Cell Biochem. 2010, 335(1-

2): 53-58.

2.057

64 Shukla S., Bharti A. C., Mahata S., Hussain S., . Hedau S., Sharma R.,

PillaiM. R., Krishna S., Chiplunkar S., Tongaonkar H., Das B.C. Application

of a multiplex PCR to cervical cells collected by a paper smear for the

simultaneous detection of all mucosal human papillomaviruses (HPVs) and

typing of high-risk HPV types 16 and 18. J Med Microbiol. 2010, 59: 1303-

1310.

2.71

65 Sobti R. C., N. Singh, Hussain S., Suri V., Bharadwaj M., Das B. C.

Deregulation of STAT-5 isoforms in the development of HPV-mediated

cervical carcinogenesis. J Recept Signal Transduct Res. 2010, 30(3): 178-

188.

1.09

66 Showket Hussain and Mausumi Bharadwaj. Telomeres, Telomerase and

Cancer. Cancer News. 2010, 4 (3), 9-10.

67 Kohaar I., Kumar J., Thakur N., Hussain S., Niyaz M. K., Das B.C., Sengupta

S., Bharadwaj M. Homocysteine levels are associated with cervical cancer

independent of methylene tetrahydrofolate reductase gene (MTHFR)

polymorphisms in Indian population. Biomarkers. 2010, 15(1): 61-68.

2.016

68 Bharadwaj M, Hussain S, Nasare V., Das B. C. HPV & HPV vaccination:

issues in developing countries. Indian J Med Res. 2009,130(3): 327-333. 2.061

69 Hussain S, Bharti A.C., Salam I., Bhat M.A., Mir M.M., Hedau S., Siddiqi

M.A., Basir S.F., Das B.C.Transcription factor AP-1 in esophageal squamous

cell carcinoma: alterations in activity and expression during human

Papillomavirus infection. BMC Cancer. 9: 329.

3.2

70 Shukla, S., A. C. Bharti, S. Hussain, S. Mahata, S. Hedau, U. Kailash, V.

Kashyap, S. Bhambhani, M. Roy, S. Batra, G. P. Talwar and B. C. Das.

Elimination of high-risk human papillomavirus type HPV16 infection by

'Praneem' polyherbal tablet in women with early cervical intraepithelial

lesions. J Cancer Res Clin Oncol. 2009,135(12): 1701-1709.

3.081

71 Shukla S, Bharti A. C., Mahata S., Hussain S, Kumar R., Hedau S.,Das B.

C. . Infection of human papillomaviruses in cancers of different human organ

sites. Indian J Med Res. 2009, 130(3): 222-233.

2.061

72 Sobti R. C., Singh N., Hussain S. , Suri V. , Bharti A. C., Das B. C..

Overexpression of STAT3 in HPV-mediated cervical cancer in a north Indian

population. Mol Cell Biochem. 2009, 330(1-2): 193-199.

2.05

73 Thakur, N., S. Hussain, I. Kohaar, R. Tabassum, V. Nasare, P. Tiwari, S. Batra,

S. Bhambhani, B. C. Das, S. F. Basir, D. Bharadwaj and M. Bharadwaj.

Genetic variant of CCND1: association with HPV-mediated cervical cancer in

Indian population. Biomarkers. 2009,14(4): 219-225.

2.016

74 Shukla S, Hedau S, Hussain S, Kumar R, Tyagi A, Pande S ,Varghese P, Kaur

H, Bharti A.C., Bharadwaj M., Das B. C. Biology of HPV and Human Cancer.

Indian J Clinical Biochem. 2009, 22 (Supl.): 87.

0.5

75 Kohaar I.,Hussain S., Thakur N., Tiwari P., Nasare V., Batra S., Singh V.,

Bhambani S., Das B. C., Sarkar D. P., Bharadwaj M. Association between

human leukocyte antigen class II alleles and human papillomavirus-mediated

cervical cancer in Indian women. Hum Immunol. 2009, 70(4): 222-229.

1.994

76 Salam I., Hussain S. , Mir M. M., Dar N.A., Abdullah S., Siddiqi M. A., Lone

R. A., S. A. Zargar S. A.,Sharma S., Hedau S., Basir S. F., Bharti A. C., Das

B. C. Aberrant promoter methylation and reduced expression of p16 gene in

esophageal squamous cell carcinoma from Kashmir valley: a high-risk area.

Mol Cell Biochem. 2009, 332(1-2): 51-58.

2.057

77 Das B. C., S. Hussain, V. Nasare and M. Bharadwaj (2008). Prospects and

prejudices of human papillomavirus vaccines in India. Vaccine. 26(22): 2669-

2679.

3.23

78 Neyaz M. K., Kumar R. S., Hussain S., Naqvi S. H., Kohaar I., Thakur N. ,

Kashyap V., Das B. C., Husain S. A., Bharadwaj M. Effect of aberrant

promoter methylation of FHIT and RASSF1A genes on susceptibility to

cervical cancer in a North Indian population. Biomarkers. 2008,13(6): 597-

606.

2.016

Abstracts presented/ published in International conferences /Proceedings: More than 100.

1. Sheeraz Un Nazir, Ramesh Kumar, Ankita Singh, Asiya Khan, Pranay Tanwar, Richa Tripathi,

Ravi Mehrotra, Showket Hussain “Transcription factor Ets-1 regulates matrix metallo-

proteinase-9 expression in human breast cancer” International conference (BCM-2019) at

Convention center, JNU, New Delhi.

2. Ankita Singh, Showket Hussain. MRAS and FOXA1 are regulated epigenetically in Breast

Cancer. 03rd-05th October 2018 at 2nd National Post-doctoral Symposium held at CCMB,

Hyderabad, India.

3. Sheeraz Un Nazir, Ramesh Kumar, Dil-Afroze, Ishrat Rasool, Banashree Banerjee, Ravi

Mehrotra, Showket Hussain: Expression of Ets-1 in breast cancer among Indian population.

26-28th April 2018, World Cancer Congress, New Delhi, India.

4. Richa Tripathi, Showket Hussain, Ankita Singh and Ravi Mehrotra. Head and Neck Cancer:

Advances in Screening, Early detection and Treatment strategies. ICUCPR-2017 International

Conference on Updates in Cancer Prevention and Research. 14-16 Febuary 2017.

BABASAHEB BHIMRAO AMBEDKAR UNIVERSITY (A Central University) Vidya

Vihar, Rae Bareli Road, Lucknow-226025 (U.P.) INDIA.

5. Vineeta Sharma, Subhash Chandra Sonkar, Showket Hussain, Shweta Sharma, Pallavi

Singhal, Daman Saluja, V.G Ramachndran, Mausumi Bharadwaj. The burden and risk factors

of multiple reproductive tract infections among HIV-seropositive women in north India, June

9-12, 2014 in Atlanta, GA. USA.

6. Mausumi Bharadwaj, Showket Hussain, Anoop kumar, Lutz Gissmann & B. C. Das.

Development of second generation HPV vaccine: DNA based India specific HPV 16 variant

vaccine. 4th annual conference of Indian Immunology Society. IMMUNOCON 2013,

organized by department of Biochemistry, UCMS, GTB Hospital (University of Delhi) from

15-17 November 2013.

7. Shweta Sharma, Showket Hussain, V.G Ramachndran, Sonal Sharma, Shukla Das &

Mausumi Bharadwaj. Evaluation of role of SNPs at exon 3 (381) and exon 4 (684) of Notch-3

gene in HPV associated cervical carcinogenesis, 4th annual conference of Indian Immunology

Society. IMMUNOCON 2013, organized by department of Biochemistry, UCMS, GTB

Hospital (University of Delhi) from 15-17 November 2013.

8. Vineeta Sharma, Subhash Chandra Sonkar, Showket Hussain, Shweta Sharma, Pallavi

Singhal, Daman Saluja, V.G Ramachndran, Mausumi Bharadwa & M.A. Khan, prevalence of

Reproductive Tract Infections (RTI) in HIV-Seropositive women in North- India, 4th annual

conference of Indian Immunology Society. IMMUNOCON 2013, organized by department of

Biochemistry, UCMS, GTB Hospital (University of Delhi) from 15-17 November 2013.

9. Showket Hussain, Neha Singh, Irfana Salam, Mohammad Akbar Bhat, Nandita Kakkar ,

Mohammad Muzaffar Mir Mushtaq A. Siddiqi, Seemi Farhat Basir, Alok C. Bharti , Mausumi

Bharadwaj, Bhudev C. Das. The c-Rel overdrives p65 subunit during functional NF-kB

complex formation in Esophageal Squamous Cell Carcinoma: Alterations in DNA binding

activity and expression following Human Papillomavirus infection. Accepted in 12th OESO

world congress held from 27th -30th August 2013 in Paris (France)'

10. Showket Hussain, Vipul Chaudhary, Pamela Singh Shweta Sharma, Neha Singh, Mohammad

Akbar Bhat, Nandita Kakkar , Mohammad Muzaffar Mir, Mushtaq A. Siddiqi, Bhudev C.

Das, Mausumi Bharadwaj. Role of hsa-mir146a polymorphism (rs2910164) in esophageal

squamous cell carcinoma. 32nd annual convention of Indian Association for Cancer Research,

organized by ACBR, university of Delhi North-campus from13-16 February 2013.

11. Showket Hussain, Heena Malik, Shweta Sharma, Pallavi Singhal, Neha Singh, Mohammad

Akbar Bhat, Nandita Kakkar , Mohammad Muzaffar Mir, Mushtaq A. Siddiqi, , Bhudev C.

Das, Mausumi Bharadwaj. To elucidate the significance of nuclear factor kappa B (NF-kB1-

94 Insertion/Deletion) Promoter Polymorphism in esophageal squamous cell carcinoma, 32nd

annual convention of Indian Association for Cancer Research, organized by ACBR, university

of Delhi North-campus from13-16 February 2013.

12. Showket Hussain, Upma Sharma, Anoop Kumar, Neha Singh, Mohammad Akbar Bhat,

Mohammad Muzaffar Mir, Mushtaq A. Siddiqi, Mausumi Bharadwaj. Role of Toll Like

Receptors (TLR-4, TLR-6 and TLR-9) in esophageal squamous cell carcinoma, 32nd annual

convention of Indian Association for Cancer Research, organized by ACBR, university of

Delhi North-campus from13-16 February 2013.

13. Anoop Kumar, Showket Hussain, Bhudev C. Das, Mausumi Bharadwaj, Evaluation of

immunogenicity of Human papillomavirus type 16 full length L1 gene variants in cancer of

uterine cervix: In silco approach, 32nd annual convention of Indian Association for Cancer

Research, organized by ACBR, university of Delhi North-campus from13-16 February 2013.

14. Rupal Sinha, Showket Hussain, R Suresh Kumar, Kapil Kumar, Pankaj Pande, , Shivendra

Singh, Dinesh Chandra Dovel, Seemi Farhat Basir, Mausumi Bharadwaj. MGMT and

RASSAF1 gene promoter methylation in sporadic colorectal cancer in Indian Population.

15. Shweta Sharma, Showket Hussain, Mausumi Bharadwaj. Down regulation of tumour

suppressor gene p21 in progression of uterine cervical carcinogenesis, 32nd annual convention

of Indian Association for Cancer Research, organized by ACBR, university of Delhi North-

campus from13-16 February 2013.

16. Singhal Pallavi, Hussain Showket, Thakur Nisha, Nag Alo , Bharadwaj Mausumi. Association

of MDM2 and p53 polymorphisms with the advancement of cervical carcinoma, 32nd annual

convention of Indian Association for Cancer Research, organized by ACBR, university of

Delhi North-campus from13-16 February 2013.

17. Vineeta Sharma, Supriti Kumari, Shweta Sharma, Showket Hussain, Sunita Malik, Mausumi

Bharadwaj, Identification of Multiple Reproductive Tract Infections (RTI) in HIV-

Seropositive women in India, 32nd annual convention of Indian Association for Cancer

Research, organized by ACBR, university of Delhi North-campus from13-16 February 2013.

18. Mausumi Bharadwaj, Rupal Sinha, Showket Hussain, Dinesh Chandra Doval. Genetic and

Epigenetic studies in Colorectal Cancer, 32nd annual convention of Indian Association for

Cancer Research, organized by ACBR, university of Delhi North-campus from13-16 February

2013.

19. Mausumi Bharadwaj, Showket Hussain, Nisha Thakur Genetic alterations in Human

Cancers: Translation of miroRNAs (miRNAs) into clinical application. 3rd International

Carcinogenesis Conference 2012 held in Ram Monohar Lal Hospital, Delhi 19-21st November,

2012.

20. Thakur Nisha, Shrivastava Richa, Hussain Showket, Basir Seemi Farhat, Bharadwaj

Mausumi; Evaluation of Functional Relevance of Rare Variant of Cyclin D1 (CCND1) in

Cervical Carcinogenesis; 3rd Carcinogenesis 2012 held in Ram Monohar Lal Hospital, Delhi

19-21st November, 2012.

21. Singhal Pallavi, Hussain Showket, Thakur Nisha, Nag Alo , Bharadwaj Mausumi; Evaluation

of NFkB1-94 Insertion/Deletion Promoter Polymorphism and its functional effect in cervical

cancer, 3rd International Carcinogenesis Conference 2012 held in Ram Monohar Lal Hospital,

Delhi 19-21st November, 2012.

22. Vinay Dwivedi, Richa Shrivastava, Showket Hussain, Chaiti Ganguly, Mausumi Bharadwaj;

In vitro Evaluation of anticancer potential of Chili Pepper (Capsicum annum)-an Indian spice,

3rd International Carcinogenesis Conference 2012 held in Ram Monohar Lal Hospital, Delhi

19-21st November, 2012.

23. Anoop Kumar, Showket Hussain, Pallavi Singhal, Shweta Sharma, Bhudev C Das, Mausumi

Bharadwaj; “Evaluation of Toll Like Receptors (TLR) 9 Polymorphism in Cancer of Uterine

Cervix in North Indian Population” 3rd International Carcinogenesis Conference 2012 held in

Ram Monohar Lal Hospital, Delhi 19-21st November, 2012.

24. Kapil Bandi, Showket Hussain, Richa Tripathi, Nagarjun Rao HT, A. K. Sarda., and

Mausumi Bharadwaj; Immunohistochemical evaluation of α and β Estrogen receptors in

Prostate Carcinoma; 3rd International Carcinogenesis Conference 2012 held in Ram Monohar

Lal Hospital, Delhi 19-21st November, 2012.

25. Shweta Sharma, Showket Hussain, Mausumi Bharadwaj. Evaluation of SNPs (-572 and -

634) in IL-6 gene in progression of cervical carcinogenesis; 3rd International Carcinogenesis

Conference 2012 held in Ram Monohar Lal Hospital, Delhi 19-21st November, 2012.

26. Gaurav Roy, Showket Hussain, Upma Sharma, Mohammad Misbah, Subash Gupta,

Mohammad Husain, Mausumi Bharadwaj, Association of TGF-β1 promoter polymorphisms

in Hepatitis B Virus mediated Hepatocellular Carcinoma in Indian population 3rd International

Carcinogenesis Conference 2012 held in Ram Monohar Lal Hospital, Delhi 19-21st November,

2012.

27. Richa Tripathi, Gayatri Rath, Shweta Sharma, Pallavi Singhal, Showket Hussain, Poonam

Jawanjal , Mausumi Bhardwaj; Alterations of Jagged-1 protein in Invasive squamous

carcinoma of human cervix: Indian scenario. 3rd International Carcinogenesis Conference 2012

held in Ram Monohar Lal Hospital, Delhi 19-21st November, 2012.


Bharadwaj; Identification of Reproductive Tract Infections (RTI) in Human

Immunodeficiency Virus (HIV) positive women in India. 3rd International Carcinogenesis

Conference 2012 held in Ram Monohar Lal Hospital, Delhi 19-21st November, 2012.

29. Nisha Thakur, Showket Hussain, Bhudev C. Das Seemi Farhat Basir, Mausumi Bharadwaj.

Prediction of Novel Human miRNAs/miRNA Target Sites in Association with SNP

(rs678653) at 3’UTR of CCND1: In-silico Approach. AICTE sponsored 1st International

conference on Biosciences & Bioengineering: A collaborative approach. To be held at

department of Biotechnology, IMS Engineering college Ghaziabad, 6-7 July 2012.

30. Richa Shrivastava, Showket Hussain, Kapil Bandil and Mausumi Bharadwaj. Evaluation of

Anti-Cancer Potential Of Tamoxifen-Loaded Nanoparticles in Breast Cancer cell lines. AICTE

sponsored 1st International conference on Biosciences & Bioengineering: A collaborative

approach. To be held at department of Biotechnology, IMS Engineering college Ghaziabad, 6-

7 July 2012.

31. Mausumi Bharadwaj, Showket Hussain, Nisha Thakur. Genetic and Epigenetic Regulation

of Carcinogenesis in Human Papilloma Virus associated Epithelial Cancers. 3rd International

Cancer Research Symposium 2012. Organized by Calcutta University, to be held in December

18-21, 2012, Kolkata, INDIA

32. Mausumi Bharadwaj, Showket Hussain, Nisha Thakur. Genetic alterations in Human

Cancers: Translation of miroRNAs (miRNAs) into clinical application. Carcinogenesis 2012.

Organized by Department of Biochemistry South campus Delhi University. To be held

November 2012

33. Shweta Sharma, Showket Hussain and Mausumi Bharadwaj. Evaluation of SNPs (-572 and -

634) in IL-6 gene in progression of cervical carcinogenesis. Carcinogenesis 2012. Organized

by Department of Biochemistry South campus Delhi University. To be held November 2012.

34. Singhal Pallavi, Hussain Showket , Thakur Nisha, Nag Alo , Bharadwaj Mausumi. Evaluation

of NFkB1-94 Insertion/Deletion Promoter Polymorphism and its functional effect in cervical

cancer. Carcinogenesis 2012. Organized by Department of Biochemistry South campus Delhi

University. To be held November 2012.

35. Gaurav Roy, Showket Hussain, Upma Sharma, Mohammad Misbah, Subash Gupta,

Mohammad Husain, Mausumi Bharadwaj. Association of TGF-β1 promoter polymorphisms

in Hepatitis B Virus mediated Hepatocellular Carcinoma in Indian population. Carcinogenesis

2012. Organized by Department of Biochemistry South campus Delhi University. To be held

November 2012.

36. Kapil Bandil, Showket Hussain, Richa Tripathi, Nagarjun Rao HT, A. K. Sarda., and

Mausumi Bharadwaj. Immunohistochemical evaluation of α and β Estrogen receptors in

Prostate Carcinoma. Carcinogenesis 2012. Organized by Department of Biochemistry South

campus Delhi University. To be held November 2012.

37. Anoop Kumar, Showket Hussain, Pallavi Singhal, Shweta Sharma, Bhudev C Das, Mausumi

Bharadwaj. Evaluation of Toll Like Receptors (TLR) 9 polymorphism in cancer of uterine

cervix in North Indian Population. Carcinogenesis 2012. Organized by Department of

Biochemistry South campus Delhi University. To be held November 2012.

38. Vinay Dwivedi1, Richa Shrivastava, Showket Hussain, Chaiti Ganguly, Mausumi Bharadwaj.

In vitro Evaluation of anticancer potential of Chili Pepper (Capsicum annum)-an Indian spice.

Carcinogenesis 2012. Organized by Department of Biochemistry South campus Delhi

University. To be held November 2012.

39. Thakur Nisha, Shrivastava Richa, Hussain Showket, Basir Seemi Farhat, Bharadwaj

Mausumi. Evaluation of Functional Relevance of Rare Variant of Cyclin D1 (CCND1) in

Cervical Carcinogenesis. Carcinogenesis 2012. Organized by Department of Biochemistry

South campus Delhi University. To be held November 2012.

40. Richa Tripathi, Gayatri Rath, Shweta Sharma, Poonam Jawanjal ,Showket Hussain, Mausumi

Bhardwaj. Alterations of Jagged-1 protein in Invasive squamous carcinoma of human cervix:

Indian scenario. Carcinogenesis 2012. Organized by Department of Biochemistry South

campus Delhi University. To be held November 2012.


Bharadwaj. Identification of Reproductive Tract Infections (RTI) in Human

Immunodeficiency Virus (HIV) positive women in India. Carcinogenesis 2012. Organized by

Department of Biochemistry South campus Delhi University. To be held November 2012.

42. Mausumi Bharadwaj, Nisha Thakur , Showket Hussain. Human Papilloma Virus associated

epithelial cancers: microRNA (miRNA) mediated regulation of carcinogenesis. Organized by

Department of Biochemistry South campus Delhi University. To be held November 2012.

43. Singhal Pallavi, Hussain Showket, Thakur Nisha, Nag Alo , Bharadwaj Mausumi. Functional

analysis of NFkB1-94 Insertion/Deletion Promoter Polymorphism in cervical cancer. BICON

2012. Organized by Department of Nursing and Faculty of Science, BiyaniGirls College,

Jaipur, India during Sept.17-19, 2012.

44. Showket Hussain, Neha Singh, Pallavi Singhal, Mausumi Bharadwaj, The realm of Human

Papilloma virus in epithelial cancers: the genetic and epigenetic regulation of carcinogenesis.

International conference on genes, genetic and genomics today & tomorrow Human concerns

and XXXVII annual conference of the Indian Society of Human Genetics (ISHG), organized

by Panjab University Chandigarh, India, 3-5th March, 2012.

45. R. C Sobti, Neha Singh, Showket Hussain, Vanita Suri Mausumi Bharadwaj. Oncogenic

signaling in cerivical cancer: the central role of HPV infection. International conference on

genes, genetic and genomics today & tomorrow Human concerns and XXXVII annual

conference of the Indian Society of Human Genetics (ISHG), organized by Panjab University

Chandigarh, India, 3-5th March, 2012.

46. Mausumi Bhardawaj, Richa Shrivastava, Showket Hussain. Embracing a cuisine rich in

Indian spices serve as strong anticancer punch. International Conference on Frontiers in

Biological researches (ICFBR) organized by Dept. of Human Physiology with Community

Health, Vidyasagar university West Bengal, India on 26-27th February, 2012.

47. R. C Sobti, Neha Singh, Showket Hussain, Vanita Suri, Nandita Kakkar, SK Singh, Mausumi

Bharadwaj, BC Das. Role of signal transducer and activator of transcription (STATs)

transcription factor in cervical and prostate cancers: the STAT signaling crosstalk. 98th Indian

Science Congress, Frontiers in science and Technolgogy. Organized by SRM university Tamil

Nadu, January 3-7, 2011

48. Nisha Thakur, Showket Hussain, Bhudev C. Das Seemi Farhat Basir, Mausumi Bharadwaj.

Prediction of Novel Human miRNAs/miRNA Target Sites in Association with SNP (rs678653)

at 3’UTR of CCND1: In-silico Approach. AICTE sponsored 1st International conference on

Biosciences & Bioengineering: A collaborative approach. To be held at department of

Biotechnology, IMS Engineering college Ghaziabad, 6-7 July 2012

49. Richa Tripathi , Gayatri Rath, Poonam Jawanjal , Shweta Sharma, Showket Hussain ,

Mausumi Bhardwaj. Association between Notch-1 protein and HPV associated Invasive

Squamous Carcinoma of human cervix. 31st Annual Convention of the Indian Association of

Cancer Research held at Navi-Mumbai 26-29th January, 2012.

50. Richa Tripathi , Gayatri Rath, Poonam Jawanjal, Shweta Sharma, Pallavi Singhal, Showket

Hussain, Mausumi Bhardwaj. De-regulation of Notch-1 protein in Invasive Squamous

Carcinoma of human cervix. 59th NATCON ASI. Organized by department of anatomy SAIMS

Indore. MP. 26th-29 December, 2011.

51. R.C.Sobti, Neha Singh, Showket Hussain, Vanita Suri, Nandita Kakkar, S.K Singh, Mausumi

Bharadwaj,B.C Das. Loss of expression of Tumor Suppressor genes PML and SOCS-1 in

cervical and prostate cancers with context to elevated levels of STATs American Association

for Cancer Research (AACR) held in India, December 2011.

52. Vinay Dwivedi, Richa Shrivastava, Showket Hussain, Chaiti Ganguly and Mausumi

Bharadwaj. Comparative Analysis of Cytotoxic Potential of Clove (Syzygium aromaticum)

against Cancers of Various Anatomical origin invitro.

3rd international conference on medicinal plants and herbal medicines 19 to 21 December

2011 – Colombo, Sri Lanka

53. Singhal Pallavi, Dangi Pinki, Hussain Showket, Goel Sakshi, Sharda Nivedita, Bhambani

Suresh, Bharadwaj Mausumi. Role of p53 and MDM2 polymorphisms in molar pregnancy.

Organized by Department of Nursing and Faculty of Science, BiyaniGirls College, Jaipur,

India during Sept.19-21, 2011.

54. Nisha, Choudhary Meenakshi, Hussain Showket, Bharadwaj Mausumi. Single Nucleotide

Polymorphism (rs2910164) in hsa-miR-146a and Susceptibility for Cervical Cancer. organized

by Department of Nursing and Faculty of Science, BiyaniGirls College, Jaipur, India during

Sept.19-21, 2011. 55. Showket Hussain, Neha Singh, Irfana Salam, Mohammad Akbar Bhat, Nandita Kakkar ,

Mohammad Muzaffar Mir, Mushtaq A. Siddiqi, Seemi Farhat Basir, Alok C. Bharti , Mausumi

Bharadwaj, Bhudev C. Das. Transcription factor NF-kB in esophageal squamous cell

carcinoma: Alterations in activity and expression during Human Papillomavirus infection.

American Association for Cancer Research (AACR) to be held in Florida, USA in April 2011.

56. Neha Singh ., Showket Hussain.,Vanita Suri., Mausumi Bharadwaj., B.C Dasc.,

R.C.Sobti.,Aberrant expression of transcription factors STAT-3 and STAT-5 and their

epigenetic control by SOCS-1 gene: The STAT signaling Crosstalk in HPV coupled cervical

carcinogenesis. American Association for Cancer Research (AACR) held in Florida, USA in

April 2011.

57. R.C.Sobti, Neha Singh , Showket Hussain., Mausumi Bharadwaj., B.C. Das., Nandita Kakkar

., S.K Singh. Role of Signal Transducer and Activator of Transcription (STATs) transcription

factors in prostate cancer: The STAT signaling Crosstalk. International Symposium on Cancer

Research and Translational inititiatives cum workshop on Flow Cytometry. 2010, Panjab

University and PGIMER, Chandigarh.

58. Showket Hussain, Mausumi Bharadwaj, Vilas Nasare, Suresh Hedau and Bhudev C Das, HPV

Infection among Adolescents in India: Impact on Vaccination Program, HPV 2010 3rd- 8th

July Montreal, Canada.

59. Showket Hussain, Alok C Bharti, Irfana Salam, Mohammad Akbar Bhat, Mohammad

Muzaffar Mir, Suresh Hedau, Mushtaq A Siddiqi, Seemi Farhat Basir and Bhudev C Das,

Differential activation and expression pattern of Transcription factor AP-1 during Human

Papillomavirus mediated esophageal carcinogenesis, International symposium on role of

genomics in clinical practice & 35th annual conference of the Indian society of Human

Genetics, 3-8th March, Venue SGPGIMS, Lucknow (India).

60. Showket Hussain, Nisha Thakur, Shantanu Sengupta and Mausumi Bharadwaj,

Homocysteine levels are associated with cervical cancer independent of methylene

tetrahydrofolate reductase gene (MTHFR) polymorphisms in Indian populations. Internatoinal

conference on environment, occupational & lifestyle concerns- Tran disciplinary approach,

envocHealth, 16-19 sept. 2009, Bangalore (oral presentation)

61. S. Hussain, AC. Bharti, I Salam, MA.Bhat, S. Hedau, MA. Siddiqi, SF. Basir, B.C. Das.

Transcription factor AP-1 in esophageal squamous cell carcinoma: Alterations in activity and

expression during human papillomavirus infection. 8th International Conference Focus: Lung

& Esophageal Cancers, 27th-29 th March 2009, New Delhi.

62. Showket Hussain,Umesh Kumar, Suresh Hedau, Gauri Shishodia, Shirish Shukla, Abhishek

Tyagi, J.K Sharma, Anita Sharma, Mausumi Bharadwaj, Alok.C. Bharti, Bhudev C Das, North

East Task force study group. Analysis of mutation in BRCA1, BRCA2 and p53 genes in North-

East India Population. 28th annual convention of Indian Association for Cancer Research and

International symposium on Emerging challenges and approaches in cancer biology. February

21- 24, 2009, IISc Bangalore.

63. Showket Hussain, Irfana Salam, M. Muzaffar Mir, Nazir A Dar, Mushtaq A Siddiqi, Safiya

Abdullah, Riyaz Ahmad Lone, Showkat A Zargar, Shashi Sharma, Suresh Hedau, Alok C

Bharti, Bhudev C Das. Aberrant Promoter Methylation and Reduced Expression of p16 Gene

in Esophageal Squamous Cell Carcinoma from Kashmir Valley –a High-Risk Area. 28th

annual convention of Indian Association for Cancer Research and International symposium on

Emerging challenges and approaches in cancer biology. February 21- 24, 2009, IISc

Bangalore.

64. Showket Hussain, Shirish Shukla, Umesh Kumar, Abhishek Tyagi, Sutapa Mahata, Rakesh

Kumar, Prishla Varghese, Harsimrut Kaur, Anita Sharma, Suresh Hedau, Mausumi Bharadwaj,

Alok C Bharati, J. K. Sharma, Bhudev C Das. High Prevalence of specific cancers in North-

East India: Effect of environmental agents. International Symposium on the Predictive,

Preventive and Mechanistic Mutagensis & XXXIII EMSI Annual Meeting, Aligharh Muslim

University (AMU), Aligharh. Jan 1-3, 2008. (Oral presentation)

65. Showket Hussain, Shirish Shukla, Sutapa Mahata, Rakesh Kumar, Abhishek Tyagi, Prishla

Varghese, Harsimrut Kaur, Alok Mishra, Suresh Hedau, Alok C Bharti and Bhudev C Das.

“Analysis of Promoter Hypermethylation of E-Cadherin Gene in Cervical Cancer”. 26th

Annual Convention of Indian Association for Cancer Research and International Symposium

on Translational Research in Cancer, Bhubaneswar, Orissa, 17th to 19th January, 2007.

66. Showket Hussain, Shirish Shukla, Rakesh Kumar, Umesh Kumar, Irfana Salam, Shakeel-ul-

Rehman, Seemi Farhat Basir, Alok C. Bharti, Mohd. Akbar Bhat, Mushtaq A. Siddiqi, Bhudev

C. Das. “The Role of c-Fos and Fos Related Antigen-1 (Fra-1) in the Pathogenesis of

Esophageal Carcinoma” in International Symposium on Genomic Instability and Cancer held

at Srinagar, 22-26, July, 2007. (Oral presentation)

67. Gaurav Roy, Showket Hussain, Mohammad Misbah, Subash Gupta, Mohammad Husain,

Mausumi Bharadwaj. Role of TGF-β1 -509C/T polymorphism in Hepatitis B Virus associated

Hepatocellular Carcinoma in Indian Population presented in 30th Annual Convention of Indian

Association for Cancer Research and International symposium on “Signaling Network and

Cancer” February 06-09, 2011, Indian Institute of Chemical Biology, Kolkata.

68. Anoop Kumar, Showket Hussain, Bhudev C Das and Mausumi Bharadwaj; Development of

DNA vaccine constructs of Indian specific Human Papillomavirus type 16 variants presented

in 30th Annual Convention of Indian Association for Cancer Research and International

symposium on “Signaling Network and Cancer” February 06-09, 2011, Indian Institute of

Chemical Biology, Kolkata.

69. Mausumi Bharadwaj, Showkat Husain, Anoop Kumar, Vilas Nasare and Bhudev C. Das.

Second Generation Vaccine: A suitable alternative?, 4th Biennial conference of Asia Oceania

research organization on Genital Infection & Neoplasia (AOGIN), 26th – 28th March 2010 New

Delhi.

70. Mausumi Bharadwaj, Showket Hussain and Nisha thakur. Genetic Basis of HPV mediated

Cervical Cancer in Indian Women” in International Conference on Systems in Medicine and

Biology held in IIT, Kharagpur, W Bengal 16-18th December, 2010.

71. Neha Singh, Showket Hussain, Vanita Suri, Alok. C. Bharti, Mausumi Bharadwaj, Bhudev

C. Das and R. C.Sobti. Loss of SOCS-1 Gene Expression and its methylation mediated

silencing in the development of HPV mediated cervical carcinogenesis. 4th Biennial

Conference of Asia Oceania research organisation on Genital Infections and Neoplasia to be

held from March 26th - 28th, 2010, in New Delhi, India

72. Rakesh Kumar, Showket Husain, Alok Mishra, Bhupesh K. Prusty, Alok C. Bharti, Bhudev

C. Das, Transcriptional Regulation of HPV: Role of fra-1 and c-fos, 78th Annual Meeting of

the Society of Biological Chemists (India),organized by National Center for Cell Science,

Pune, from October 30 to November 1, 2009.

73. Mausumi Bharadwaj, Showket Hussain, Md. Kausar Neyaz, Veena Singh, Suresh

Bhambhani, Bhudev C. Das and Ashok Sehgal, Effects of genetic and epigenetic modifications

of tumor suppressor genes on susceptibility to cervical cancer in in North Indian population.

International conference on environment, occupational & lifestyle concerns- Tran disciplinary

approach, envocHealth, 16-19 sept. 2009, Bangalore

74. Joyti Malik, Showket Hussain, Vilas Nasare, Anoop Kumar, Harsha Gaikwad, Chaiti

Ganguly, Nivedita Sarda, HP Anand, Sudha Salhan, Bhudev C. Das and Mausumi Bharadwaj.

HPV detection by using urine sample compared with cervical smear in woman of reproductive

age group with or without High Risk factors, 4th Biennial conference (international) of Asia

Oceania research organization on Genital Infection & Neoplasia (AOGIN), 26th – 28th March

2010, New Delhi.

75. Malasha Kumari, Mausumi Bharadwaj, Vilas Nasare, Showket Hussain, Shashi Sharma,

Ashok Seghal, Bhudev C. Das, Awareness of cervical cancer and Human Pappilomavirus

infection among school childern in India: Parental Attitude towards acceptance of Human

Pappilomavirus (HPV) Vaccination, 4th Biennial conference (international) of Asia Oceania

research organization on Genital Infection & Neoplasia (AOGIN), 26th – 28th March 2010,

New Delhi.

76. RC Sobti, Neha Singh, Showket Hussain, Vanita Suri, Nandita Kakkar, S K Singh, Mausumi

Bharadwaj, BC Das. Aberrant Expression of STAT-3 and STAT-5 and their Epigenetic

Control by SOCS-1 Gene in Cervical and Prostate Cancer presented in International

Conference on Genomics, Genetic Disease and Diagnostics & XXXVI Annual Conference of

the Indian Society of Human Genetics held on February 14-16, 2011.

77. Mausumi Bharadwaj, Showket Hussain and Nisha thakur. “Host Pathogen Interactions during

development of Cervical Carcinogenesis” in 30th Annual Conference of Society of Toxicology

(STOX) and Symposium on Strategies for Safety Study Requirements for Herbal Formulations

held in Jamia Hamdard, New Delhi, December 9-11, 2010.

78. Singhal Pallavi, Thakur Nisha, Hussain Showket, Bharadwaj Mausumi, “The Role of IL-10

promoter gene polymorphisms in the development of cervical cancer in Indian women. “29th

Annual Convention of IACR 2010” (20th-23rd Feb 2010) at Amrita Institute of Medical

Sciences, Kochi.

79. Rakesh Kumar, Showket Hussain, Alok Mishra, Bhupesh K. Prusty, Alok C. Bharti, Bhudev

C. Das, Crosstalk of Fos Related Antigen (Fra-1) in Tumor Microenvironment: Friend or Foe?

In the 3rd International Symposium on Translational Cancer Research, Bhubaneswar, 18th -

21st Dec 2009.

80. Mausumi Bharadwaj, Showket Hussain ,Vilas Nasre, Suresh Hedau, and B.C.Das. Human

Papillomavirus (HPV) Infection Among Pre-adolescent Children in India : Impact on

Vaccination Program. Biennial conference (interm ) of Asia Oceania research organization on

Genital Infection & Neoplasia (AOGIN), 25th – 26th 2009, Kolkata.

81. A.C. Bharti, S. Shukla, S. Hussain, G. Shishodia, S. Hedau, Nisha Takur, M. Bharadwaj and

B.C. Das. WHO’s Regional HPV Reference Laboratory. Asia Oceania research organisation

on Genital Infections-India Biennial Conference, Kolkata India. April 25-26, 2009.

82. Shakti B. Khanna, B. C Das, Showket Hussain, Mausumi Bhardwaj. Human Papilloma Virus

(HPV) infection in Kashmiri Women. Biennial conference (interm ) of Asia Oceania research

organization on Genital Infection & Neoplasia (AOGIN), 25th – 26th 2009, Kolkata.

83. Shirish Shukla, Alok C Bharti, Sutapa Mahata, Showket Hussain, Rakesh Kumar , Suresh

Hedau, Bhudev C Das. Carcinogenic effect of HPV: Beyond cervical cancer. Biennial

conference of Asia Oceania research organization on Genital Infection & Neoplasia (AOGIN),

25th – 26th April 2009, Kolkata.

84. Mausumi Bharadwaj, Showket Hussain, Vilas Nasre, Suresh Hedau, and B.C.Das. Human

Papillomavirus (HPV) Infection Among Pre-adolescent Children in India: Impact on

Vaccination Program. Biennial conference of Asia Oceania research organization on Genital

Infection & Neoplasia (AOGIN), 25th – 26th April 2009, Kolkata. (Oral presentation).

85. Thakur Nisha, Hussain Showket, Kohaar Indu, Nasare Vilas, Tiwari Pratibha, Batra Swaraj,

Bhambhani Suresh, Basir Seemi Farhat, Bharadwaj Dwaipayan and Bharadwaj Mausumi.

“Influence of Cyclin D1 G870A Single Nucleotide Polymorphism on Cervical cancer in Indian

Population” in the International Symposium on Tribal Health (ISTH) at RMRCT (ICMR)

Jabalpur, from 27th Feb to 1st March 2009.

86. Showket Hussain, AC Bharti, I salam, MA Bhat, S Hedau, MA siddiqi SF Basir, BC Das.

Transcription factor AP-1 in esophageal sqamous cell carcinoma: Alterations in activity &

expression during Human Papilloma virus infection. Presented in 8th International Conference

Focus: Lung & Esophageal Cancers, 27th-29 th March 2009, New Delhi.

87. Mausumi Bharadwaj, Showket Hussain, Nisha Thakur, Irfana Salam, Mohammad Akbar

Bhat, Mohammad M Mir, Mushtaq A Siddiqi, Seemi Farhat Basir, Bhudev C Das. Analysis of

Single Nucleotide Polymorphism G870A of Cyclin D1 Gene in Esophageal Squamous Cell

Carcinoma. Presented in 8th International Conference Focus: Lung & Esophageal Cancers,

27th-29 th March 2009, New Delhi.

88. Abhishek Tyagi, Shirish Shukla, Sutapa Mahata, Rakesh Kumar Tekade, Showket Hussain,

Umesh Kumar, Gauri Shishodia, Suresh Hedau, Alok C. Bharti, Bhudev C. Das. Anticancer

Nanomedicines: Current Status and Future Opportunities. Indo-US Symposium on Cancer

Nanotechnology, Feb 4-6th 2009.

89. Singh Neha, Hussain Showket, Suri Vanita, Bharti Alok. C, Das B. C., Sobti R. C. Analysis

of Promoter Methylation of SOCS-1 Gene in Cervical Cancer. 28th annual convention of

Indian Association for Cancer Research and International symposium on Emerging challenges

and approaches in cancer biology. February 21- 24, 2009, IISc Bangalore.

90. Showket Hussain, Irfana Salam, Mohammad M Mir, Nazir A Dar, Mushtaq A Siddiqi, Safiya

Abdullah, Riyaz A Lone, Showkat A Zargar, Shashi Sharma, Suresh Hedau, Alok C Bharti,

Bhudev C Das. Aberrant Promoter Methylation and Reduced Expression of p16 Gene in

Esophageal Squamous Cell Carcinoma from Kashmir Valley -a High-Risk Area. 28th annual

convention of Indian Association for Cancer Research and International symposium on


Bangalore.

91. Thakur Nisha , Hussain Showket, Kohaar Indu, Nasare Vilas, Tiwari Pratibha, Bhambhani

Suresh, Basir Seemi Farhat, Bhudev C Das, and Bharadwaj Mausumi. Association of SNP at

G870A of CCND1 with HPV Mediated Cervical Cancer in Indian Population. 28th annual



Bangalore.

92. Suresh Hedau, Shailesh Sahay, Shirish Shukla, Rakesh Kumar, Sutapa Mahata, Showket

Hussain, Shailja Pande, Prishla Varghese, Alok C Bharti, Bhudev C Das. Expression of Breast

Cancer susceptibility Genes BRCA1 and BRCA2 proteins and their correlation with clinical

staging in Breast Cancer. 28th annual convention of Indian Association for Cancer Research

and International symposium on Emerging challenges and approaches in cancer biology.

February 21- 24, 2009, IISc Bangalore.

93. Shirish Shukla, Alok C. Bharti, Showket Hussain, Sutapa Mahata, Suresh Hedau, Uma

Kailash, Veena Kashyap, Suresh Bhambhani, Meera Roy, Swaraj Batra, G.P. Talwar, Bhudev

C. Das. Elimination of High-Risk Human Papillomavirus Type HPV16 Infection by ‘Praneem’

Polyherbal Tablet in Women with Early Cervical Intraepithelial Lesions. 28th annual



Bangalore.

94. Shirish Shukla, Alok C. Bharti, Gauri Shishodia, Sutapa Mahata, Showket Hussain, Suresh

Hedau, Veena Kashyap, Veena Singh, Suresh Bhambhani, Partha Basu, G.P. Talwar, Bindu

Dey and Bhudev C. Das. Clinical evaluation of anti-Human papillomavirus activity of

Curcumin and a Curcumin-based polyherbal formulation “BASANT”. 28th annual convention

of Indian Association for Cancer Research and International symposium on Emerging

challenges and approaches in cancer biology. February 21- 24, 2009, IISc Bangalore.

95. A.C. Bharti, S. Shukla, S. Hussain, G. Shishodia, S. Hedau, Nisha Takur, M. Bharadwaj and

B.C. Das. Development of South East Asian Regional HPV Laboratory for Monitoring HPV

vaccine Program under WHO’s Global HPV Laboratory Network (HPV-LabNet) at ICPO,

NOIDA. 28th annual convention of Indian Association for Cancer Research and International

symposium on Emerging challenges and approaches in cancer biology. February 21- 24, 2009,

IISc Bangalore.

96. Shukla, S., Hussain, S., Mahata, S., Kumar, R., Joshi, S., Tyagi, A., Mishra, A., Varghese,

P., Kaur, H., Pande, S., Hedau, S. Bharti, A.C.,and Das, B.C. “Development of Rapid, Cost

Effective and Sensitive Multiplex PCR Assay for Detection of High Risk HPV Type 16 and

18” at 30th All India Cell Biology Conference, Delhi. 2007

97. Md. Kausar Neyaz, R Suresh Kumar, Showket Hussain, Indu Kohaar, Nisha Thakur, B C Das,

Syed Akhtar Husain and Mausumi Bharadwaj. “Promoter Methylation of FHIT and RASSF1A

genes in Cancer of Uterine Cervix: Its relationship with clinical outcome.” at 26th Annual

Convention of Indian Association for Cancer Research and International Symposium on

Translational Research in Cancer held in January 17-19, in Bhubaneswar. 2007

98. Mausumi Bharadwaj, Vilas Nasare, Suresh Hedau, Showket Hussain, Indu Kohaar, Nisha

Thakur, Shirish Shukla, Smitha Asthana, Raj Narain, Alok C Bharti, B C Das. “Prevalence of

Human Papillomavirus (HPV) infection among pre-adolescent children in India.” 24th

International Papillomavirus Conference and Clinical Workshop in Beijing, China. 2007.

99. Shirish Shukla, Showket Hussain, Shailja Pande, Prishla Varghase, Harsimrut Kaur, Bhupesh

Prusty, Neeraj Jain, Alok Mishara, Gitanjli Bugnait, Sanjay Katiyar, V. Gopal Krishna, Suresh

Hedau, Mausumi Bharadwaj, Alok C Bharti, BC Das. Mapping of Human Papillomavirus

infections in cancer & pre-cancers of different organ sites in India. 24th International

Papillomavirus Conference and Clinical Workshop in Beijing, China. 2007

100. Shirish Shukla, Suresh Hedau, Showket Hussain, Rakesh Kumar, Abhishek Tyagi, Shailja

Pande, Prishla Varghese, Harsimrut Kaur, Alok C. Bharti, Mausumi Bharadwaj and B.C. Das.

“Biology of HPV and Human Cancer” in 34th National Conference of Association of Clinical

Biochemists of India held at India Habitat Center, New Delhi during 17th -20th December,

2007.

101. Kaur, H., Varghese, P., Hussain, S., Kumar, R., Shukla, S., Hedau, S., Bharti, A.C. and Das,

B.C. “Development of Customized Microarrays for Early Diagnosis of Cervical Cancer” at

Second Medical Development Congress, New Delhi, India. 2006

102. Hedau, S., Kumar, R., Tyagi, A., Hussain, S., Shukla, S., Mishra, A., Mahata, S., Bharti,

A.C. and Das, B.C. “No Evidence of HPV infection in Breast Cancer as revealed by

conventional as well as Real-time PCR” at 26th Annual Convention of Indian Association for

Cancer Research, Bhuvaneshwar, Orrisa. 2007.

103. Bharti, A.C., Varghese, P., Kaur, H., Mukhtar, U., Shukla, S., Mishra, A., Hussain, S.,

Mahata, S., Kumar, R., Tyagi, A., Hedau, S. and Das, B.C. “Role of Transcription Factor

STAT3 in Human Papillomavirus 16 (HPV16)-induced cervical carcinogenesis” at 26th

Annual Convention of Indian Association for Cancer Research, Bhuvaneshwar, Orrisa. 2007

104. Mahata Sutapa, Alok Mishra, Shirish Shukla, Showket Hussain, Saurabh Maru, Rakesh

Kumar, Abhishek Tyagi, Suresh Hedau, Alok C. Bharti, And Bhudev C. Das. Molecular

Targeting of Viral Oncogene Expression by Herbal Compounds. Abstract. 6th annual

Symposium on Frontiers in Biomedical Research Nov 30th- Dec. 2nd, 2006.

List of important scientific meetings attended:

1. Organized “Hands on workshop on cervical cancer screening” from Feb. 26th – 28th ’2019 at

ICMR-NICPR, NOIDA.

2. Attended 8th Training programme on “Science Technology and Emerging Trends in

Governance” from 18th to 22nd Feb. 2019 at Indian Institute of Public administration (IIPA),

New Delhi.

3. Delivered a Lecture on “Advanced Molecular Diagnostics Techniques” at I.T.S Centre for

Dental studies and research, Muradnagar, Ghaziabad on 14th Feb. 2019.

4. Attended symposium on “Advances in Immunomics & Immune oncology” on 30th Jan. 2019

in New Delhi organized by Sun Pharma Science Foundation.

5. Attended the annual conference on “Frontiers in oncology” organized by Sun Pharma Science

foundation (SPSF)” held on Friday, 30th Nov. 2018 at AIIMS, New Delhi.

6. Organized “Hands on workshop on cervical cancer screening” from Aug 29-31’2018.

7. Attended cancer congress held in New Delhi, from April 28-29th 2018” on expression of ETS-

1 in breast cancer in Indian population

8. Organized “Hands on workshop on cervical cancer screening for pathologists” under aegis of

Indian academy of cytologists organized by division of cytopathology, ICMR-NICPR, NOIDA

from Feb 19-21’2018.

9. Conducted ICMR JRF examination at J&K July 2018.

10. Attended Genetic solutions tour organized by applied biosystems by Thermo Fisher Scientific

on August 2nd 2018, Aerocity, New Delhi.

11. Attended “Induction cum Laboratory Training programme” organized by National Tobacco

testing laboratory ICMR-NICPR NOIDA from 29th Jan – 1st Feb. 2018

12. Invited to give a talk on “Prospects and Prejudices of cervical cancer in India” in Stephenson

Cancer centre at The University of Oklahoma on March 4, 2016.

13. Attended “Life Sciences summit” in Chandigarh, New Delhi and Lucknow from 7th to 9th Dec,

2016.

14. Joint co-ordinator in workshop at “Basic molecular biology techniques relevant to cancer

research” organised by NICPR NOIDA from 6th – 9th December 2016.

15. Joint co-ordinator in workshop at “Basic molecular biology techniques relevant to cancer

research” organised by NICPR NOIDA from 18th to 21st April, 2017.

16. Attended “Pre-symposium and symposium on developing protocol for management of diabetes

and its complications” Madhu Samvaada organised by All India Institute of Ayurveda from

March 15-18, 2017.

17. Invited as penalist the first joint Gall Bladder Cancer Symposium held on November 6, 2017

at Ramalingaswami Board Room, AIIMS, New Delhi, India.Dr BRA-IRCH & National

Cancer Institute (NCI) , AIIMS New Delhi and The University of Texas M. D. Anderson

Cancer Center (MDACC).

18. Invited as penalist: National conference on emerging perspectives in nursing care. 11-12th

September 2017 at SKICC Srinagar.

19. Workshop attended (Speaker/Chairperson/Delegate): Organized two day program on

“Updates in Management of Breast Cancer” An Initiative of NCI-INDIA, AIIMS on 6th-

7th May, 2017 at JLN Auditorium, AIIMS, New Delhi.

20. Workshop conducted: 4th workshop on Basic Molecular Biology Techniques relevant to

Cancer Research April 18-21, 2017 (As Joint- coordinator).

21. Organized Hands on Workshop “Basic molecular biology techniques relevant to Cancer

Research” at NICPR, NOIDA, 6-9 December 2016. (As Joint- coordinator).

22. Participated in workshop on Cancer Research in the Media; International workshop for

Scientific Journalism; Co- Sponsored US- NCI & ICPO -ICMR on Oct. 12-14 2015.

23. Chaired the Technical Session at IILM, College of Engineering and Technology Greater

Noida on “Emerging Technology in Medical Biotechnology and Health Care” on July 29-

30, 2015.

24. Attended a meeting at American Centre, New Delhi on “ Cancer the Emperor of All

Maladies on August 6, 2015.

25. Conducted ICMR JRF examination at J&K July 2015.

26. Attended a Provocative Question (PQ) Workshop organized under the aegis of DBT, India

& NCI, US on 29th October, 2014 at Dr. B.R. Ambedkar IRCH, AIIMS, New Delhi. The

theme was 'Importance of International Collaboration in Medical Research’.

27. Conducted ICMR JRF examination at J&K on 13th July 2014.

28. Conducted workshop on PCR and its application in International conference of Dental

Specialties at ITS Dental College Ghaziabad from 9-10 May 2014. (As course Director).

29. Attended and organized International workshop in collaboration with NCI USA on “Cancer

Screening Strategies” at India International Center, Lodhi Road, New Delhi, from 13-14

September 2013.

30. Organized Hands on Workshop under ICMR Centenary Celebration “Basic molecular

biology techniques relevant to Cancer Research” at ICPO, NOIDA, 8-12 August 2011. (As

Course coordinator).

31. Attended workshop on Nexus Copy Number & Nexus Expression Training Course at MD

Anderson Cancer Center Houston Texas, USA, from April, 26-27, 2011.

32. Completed Training Course for Radiation Safety Training at MD Anderson Cancer Center

Houston Texas, USA, from January 31, 2011.

33. Passed Training Course for Animal Training at MD Anderson Cancer Center Houston

Texas, USA, from January 26, 2011.

34. Participated in a corporate seminar series on “Proteomics: Cutting edge technologies and

their applications” at ICPO, NOIDA. July 17, 2006.

35. Participated in a Mini symposium on “Recent Trends in Translational Cancer Research” at

ICPO, NOIDA. September 20th, 2006.

36. Organized a Wet Workshop under the DBT project “Development of HPV Diagnostics for

Early Detection of Cervical Cancer”.

37. Participated in a corporate seminar series on “Proteomics: Cutting edge technologies and

their applications” at ICPO, NOIDA. July 17, 2006.

38. Participated in a Mini symposium on “Recent Trends in Translational Cancer Research” at

ICPO, NOIDA. September 20th, 2006.

39. Training course on Biostatistics and Epidemiology in Biomedical Research. Held at

Institute of Cytology & Preventive Oncology (ICPO) ICMR, Noida. 4-6 August. 2008.

40. Training workshop on Spectral Confocal LASER Scaning Microscopy. Jointly organized

by Institute of Cytology & Preventive Oncology (ICPO) ICMR & LABINDIA. 27-28 July

2008.

41. Indo –US workshop on cancer stem cells venue Panjab University Chandigarh India. 25-28

July 2008.

42. National workshop on Microarray technology organized by Institute of Pathology (IOP)

New Delhi. 16-18 April 2007.

43. National workshop on Indian Society of Colposcopy and Cervical Pathology, LNJP New

Delhi 2006.

44. 1st National level multidisciplinary infection control & clinical microbiology conference

MIDCON-CM, Srinagar Kashmir Oct.1-3, 2004.

45. 4th Annual National conference on Leptospirosis held at Kashmir.13-15 October, 2006.

Awards and prizes:

Recipient of prestigious ICMR award for research conducted in Biomedical Medical

Research in under developed area for the year 2013-2014

Awarded ICMR Young Scientist International Fellowship Program for the year 2015-16.

Awarded as ICMR young scientist fellowship award for two years

Awarded Post doctoral fellowship from MD Anderson cancer Center, Houston Texas, USA

Two award winning posters: One at AACR meeting held in Florida (Proceedings published

in cancer Research Journal of cancer Research) and other at Carcinogenesis meeting held

in Delhi (Proceedings published in Journal of Carcinogenesis)

Foreign Visit(s):

1. Oklahoma state university U.S.A: Young Scientist International Fellowship Program.

2. German Cancer Centre (DKFZ) Heidelberg: Worked in Professor Lutz Gissmann’s

Laboratory in the frame of Indo-German Collaborative Research Project in the area of

vaccination for cancer development of Chimeric Genetic vaccine against Human

papilloma Type 16 virus.

3. MD Anderson Cancer Centre, Texas, USA: Worked on miRNA expression profiling in

genetically engineered mouse models of pancreatic cancer

Computer knowledge

Have done the basic Course in Computer Applications from NIIT New, Delhi

Membership:

• American Association for Cancer Research (AACR)

• Human Genome Organization (HUGO), London

• Indian Association for Cancer Research (IACR)

• Indian Society for Human Genetics (ISHG)

• Indian Leptospirosis Society of India (ILS).

Handling editor of the following Journal (s):

I. Frontiers in Oncology in Cancer Epidemiology and Prevention section:

http://loop.frontiersin.org/people/370825/overview

II. Case reports in Pathology: http://www.hindawi.com/journals/cripa/editors/

Ongoing Extramural Research Projects

As PI or Co-PI : N=11 [PI=07, Co-PI=04]

S.

No.

Title of the Project Funding Agency Amount in Rs

1 Comparative study of Genetic, Clinical and

Epidemiological factors of Breast Cancer in

Indian population (PI). Ongoing

ICMR- Task force

Duration: 5 years

2017-2022

1,01,45,200

2 Landscape of genomic alterations in Human

papillomavirus infection associated cancers- a

genomics, bioinformatics and computational

approach (PI). Ongoing

DST (Indo- Swedish)

Duration: 2 years

2017-2019

34,01,400

3. Role of cellular Transcription Factor NF-KB

and HPV in the development of esophageal

carcinogenesis (PI). Ongoing

ICMR

Duration: 3 years

2017-2020

39,11,512

http://www.hindawi.com/journals/cripa/editors/

4 Genomics of Gall Bladder Carcinoma in Indian

patients (National Task Force Project) (PI).

Ongoing

ICMR

Duration: 5 years

2018-2023

55,34,000

5 Charting histone modifications in Indian breast

cancer patients.

(PI). Ongoing (NPDF Fellowship)

DST-SERB

Duration: 2 years

2017-2019

19, 20, 000

6 A molecular understanding of the role of oral

contraceptives in the pathogenesis of cervical

cancer

(PI). Ongoing (DHR Women Scientist

Fellowship)

DHR

Duration: 3 years

2017-2020

27, 81, 000

7 Role of ETS-1 transcription factor in breast

carcinogenesis

(PI). (Ongoing ICMR SRF Fellowship)

ICMR

Duration: 3 years

2017-2019

13,70,400

8 Validation of Liquid based Cytology in the

detection of oral cancer & pre-cancer using the

Trans-epithelial brushing technique & to

explore the prevalence of HPV infection (as co-

PI). Sanctioned

ICMR

Duration: 3 years

2017-2020

47,05,600

9. Development of DNA based vaccine constructs

against HPV-16 variant: enhancement of

immunogenicity of L1 constructs and

characterization of T-cell epitope based E6/E7

constructs (as co-PI). Ongoing

ICMR

Duration: 3 years

2017-2020

57,00,000

10. Molecular epidemiology of Gall Bladder cancer

(as co-PI) sanctioned

Sister Institution Network

partners (SWINF),

MD Anderson cancer center,

Chile, AIIMS & NICPR

(Sanctioned)

Duration: 2 years

$100,000

11 A combinatorial study and evaluation of role of

therapeutic agents/inhibitors on JAK/STAT

pathway. (as co-PI). Ongoing

DST-SERB

Duration: 3 years

2017-2019

30,09,000

Projects handled at NICPR:

Task force project on role of tobacco use in causation of cancer in North-East India

Task force project on role of pesticide exposure in causation of cancer in North-East

India.

Comprehensive study of esophageal carcinoma in North- East India.

Development of Chimeric DNA-based Vaccine against Human Papillomavirus type

16 – Indo German Task-force project.

Development of Regional HPV Laboratory for Monitoring HPV Vaccine Programme

at ICPO

Detection of Human Papilloma Virus Infection In Antenatal Patients Using Urine

Sample and its impact on pregnancy outcome.

Supervisor of MD/ Ph.D/ MDS/Dissertation students/ summer trainees (Year 2014-18)

Ph.D (N=03)

1. Mr. Sandeep Sisodiya (Registered at Sharda University, Greater NOIDA) 2019-

Ongoing.

2. Mr Sheeraz Un Nazir (Registerd at Bundelkhand University, Jhansi). Title of the

Project: “Role of ETS-1 transcription factor in breast carcinogenesis”, 2015-ongoing.

3. Mr Dev Jyoti Dalal (Registered at AIIMS, New Delhi). Title of the Project: “Optical

characterization of breast cancer”, 2015-ongoing.

MD/MS (N=07)

1. Dr. Sefali. ITS Dental College & Research Centre, Ghaziabad). Title of the Project:

“Role of c-Myc mediated p53 dependent pathway in the staging of oral potentially

malignant disorders and oral squamous cell carcinoma”, 2018-2021

2. Dr. Manisha Yadav UCMS, GTB Hospital, New Delhi. Title of the Project:

“Evaluation of expression of extracellular signal regulated Kinase-1 in oral cancer’,

2018-2021.

3. Dr. Aadarsh Kumar Meena UCMS, GTB Hospital, New Delhi. Title of the Project:

“Expression of Forkhead Box P3 (FOXP3) marker in oral and oropharyngeal

carcinoma”, 2018-2021.

4. Dr. Akanksha Banga (Degree awarded) ITS Dental College & Research Centre,

Ghaziabad). Title of the Project: “H-ras oncogene alterations in Oral epithelial

dysplasia and Oral squamous cell carcinoma”, 2013-2015. ( Thesis submitted)

5. Dr. Flora Verma (Thesis submitted) ITS Dental College & Research Centre,

Ghaziabad. Title of the Project: “Expression profile of retinoblastoma gene along with

HPV status in oral potentially malignant disorders and oral squamous cell carcinoma”,

2015-2017. ( Thesis submitted)

6. Dr. Avantika Singh: (Thesis submitted) MDS, Sharda University. Title of the Project:

“Detection of human papillomavirus-16 and 18 in squamous cell carcinoma compairing

PCR results with llight microscopy”, 2015-2018. ( Thesis submitted)

7. Dr. Reema Raina ITS Dental College & Research Center, Ghaziabad. Title of the

Project: “Implicating the role of Human papillomavirus in the etiopathogenesis of Oral

Potentially Malignant Disorders and Oral Squamous Cell Carcinoma using

Mitochondrial DNA analysis”, 2016-2018. ( Thesis submitted)

8. Dr. Vishwa Bharati Gaonkar, AIIMS, New Delhi. Title of the project: “An

investigation to identify the etiopathogenesis of fibroadenoma; an ultrastructural and

physicochemical study”, 2015-2018. ( Thesis submitted)

Post-Doctoral/ Women Scientist (N=03)

1. Dr. Saba Noor (Selected for CSIR - RA) 2019

2. Dr. Anamika Priyadarshini Sil (Women scientist). Title of the Project: “A molecular

understanding of the role of oral contraceptives in the pathogenesis of cervical cancer”,

2017-2020.

3. Dr. Ankita Singh (DST-SERB). Title of the Project: “Charting histone modifications

in Indian breast cancer patients”, 2017-2019.

Project Staff (N=04)

1. Dr. Banashree Bandyopadhyay (Research Associate). Title of the Project:

“Comparative study of Genetic, Clinical and Epidemiological factors of Breast Cancer

in Indian population”, 2017- 2022.

2. Mr. Sandeep Sisodiya (SRF). Title of the Project: “Comparative study of Genetic,

Clinical and Epidemiological factors of Breast Cancer in Indian population”, 2017-

2022.

3. Mr. Atul Chikara (SRF). Title of the Project: “Landscape of genomic alterations in

Human papillomavirus infection associated cancers- a genomics, bioinformatics and

computational approach”, 2017- 2019.

4. Dr. Isha Goel (SRF). Title of the Project: “Role of cellular Transcription Factor NF-

KB and HPV in the development of esophageal carcinogenesis”, 2017-2020.

PG Dissertation [4-6 months] (N=04)

1. Ms. Sangyal, Amity University, Noida. Title of the project: “Expression of H3K14AC

in Oral Squamous Cell carcinoma”, Feb-April’2018.

2. Ms. Bisma Gul, Jamia Hamdard, New Delhi. Title of the project: “Effect of crocus

sativus (saffron) on cervical cancer”, Jan-June’2018.

3. Ms. Swati Kumar, Amity University, Noida. Title of the project: “Role of

retinoblastoma RB in oral carcinogenesis”, Jan-June’2018.

4. Ms. Ummi Amarah, M. Tech, Amity University, Noida. Title of the project:

“Studying the pattern of H3K4me2 in breast cancer patients”, Jan-June’2018.

5. Ms. Mariyam Chaudhary, MSc. Biotechnology, chandigarh university, Mohali. Title

of the project: “to check the combined effect of 17β estradiol and progesterone on

human cervical cancer cell lines”, jan-jun 2018.

6. Akshita Chhabra, M.tech Amity university,Noida. Title of the project “Uderstanding

the epigenetic landscape of HPV promotor in cervical cancer.”

7. Jyoti Rani, Meerut College Meerut, CCS University, Meerut. Title of the Project “To

understand the role and mechanism of HPV E4 & E5 oncoproteins in cervical cancer

cells”.

8. Muzdalfa Rizwan, M.M college, Modinagar. Title of the project “effect of estrogen

and levonorgestrol on triple negative breast cancer cells”

9. Umme Abiha, Amity University Noida.

Summer Training [4-6 weeks] (N=16)

1. Ms. Aditi Tomar, Guatam Buddha University, Greater Noida, University.

2. Ms. Swati Naagar, B. Tech Biotech Shobit University

3. Ms. Maryam Chaudhary, Chandigarh University.

4. Ms. Shruti Bharadwaj, Amity University, Noida.

5. Ms. Shruti Bhardiya, Amity University, Noida.

6. Ms. Shubhi A Kharbanda, M. Tech

7. Ms. Nikhat Parveen, M.Tech Biotech, Amity University Noida.

8. Ms. Pushpita Bhattacharjee, B. Tech Biotech, Shobit University

9. Mr. Piyush Goel, Amity University

10. Ms. Tanya Dogra. B. Tech. Biotech. JIIT, Noida

11. Ms. Nancy Jain, B. Tech, Amity University

12. Ms. Smriti Sarswat, B.Sc Medical Biotechnology, Amity University

13. Ms. Gargi Tiwari, B.Sc Medical Biotechnology, Amity University

14. Ms. Reny Das, B. Tech, Amity University

15. Khushboo Sinha, M.Sc (Central University of Bihar)

16. Ms. Mayur Pankhi, M.Sc. Biotechnology, Amity University, Noida.

17. Taru jain, B.tech biotechnology, JIIT, Noida.

Administrative responsibilities (2016-2018):

Acting as Nodal Officer for egovernance & Swachh Bharat Abhiyaan on the Instructions

of Honble. PM of India

Chairperson Condemnation Committee of NICPR.

Serving member of computer committee of NICPR.

Serving member of event committee (Hospitality) of NICPR.

Chairperson of NICPR. Library.

Assisting in decision making policies for the scientific growth of the Institute.

Chairperson & store in- charge (2014-till date) of NICPR.

Serving member of Purchase committee (2014-till date) of NICPR.

Dr. Showket Hussain, Scientist -D at ICMR National...

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