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C:\Users\Admin\Desktop\Dr_michael_mullan_sarasota_publications.txt Tuesday, September 04, 2012 9:00 PM
Publications By Dr. Michael Mullan
President and CEO of Roskamp Institute, Sarasota, FL
1.
2012
Sean Kennelly; Laila Abdullah; Rose Anne Kenny; Venkat Mathura; Cheryl A Luis; Benoit Mouzon;
Fiona Crawford; Michael Mullan ; Brian Lawlor
Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the
antihypertensive nilvadipine in Alzheimer's patients--an open-label trial.
International journal of geriatric psychiatry 2012;27(4):415-22.
2.
2011
Laila Abdullah; Gogce Crynen; Jon Reed; Alex Bishop; John Phillips; Scott Ferguson; Benoit
Mouzon; Myles Michael Mullan ; Venkatarajan Mathura; Michael Mullan ; et al.
Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents.
Neuromolecular medicine 2011;13(4):275-88.
3.
2011
Daniel Paris; David Beaulieu-Abdelahad; Corbin Bachmeier; Jon Reed; Ghania Ait-Ghezala; Alex
Bishop; Jin Chao; Venkat Mathura; Fiona Crawford; Michael Mullan
Anatabine lowers Alzheimer's Aß production in vitro and in vivo.
European journal of pharmacology 2011;670(2-3):384-91.
4.
2011
S P Kennelly; L Abdullah; D Paris; J Parish; V Mathura; M Michael Mullan ; F Crawford; B A
Lawlor; R A Kenny
Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug
Nilvadipine: results from a 6-week open label study.
International journal of geriatric psychiatry 2011;26(10):1038-45.
5.
2011
Corbin J Bachmeier; David Beaulieu-Abdelahad; Michael J Michael Mullan ; Daniel Paris
Epitope-dependent effects of Beta-amyloid antibodies on Beta-amyloid clearance in an in vitro
model of the blood-brain barrier.
Microcirculation (New York, N.Y. : 1994) 2011;18(5):373-9.
6.
2011
Corbin Bachmeier; David Beaulieu-Abdelahad; Michael Mullan ; Daniel Paris
Selective dihydropyiridine compounds facilitate the clearance of ß-amyloid across the
blood-brain barrier.
European journal of pharmacology 2011;659(2-3):124-9.
7.
2011
Corbin J Bachmeier; David Beaulieu-Abdelahad; Nowell J Ganey; Michael J Michael Mullan ; Gary M
Levin
Induction of drug efflux protein expression by venlafaxine but not desvenlafaxine.
Biopharmaceutics & drug disposition 2011;32(4):233-44.
8.
2011
Daniel Paris; Corbin Bachmeier; Nikunj Patel; Amita Quadros; Claude-Henry Volmar; Vincent
Laporte; Jim Ganey; David Beaulieu-Abdelahad; Ghania Ait-Ghezala; Fiona Crawford; et al.
Selective antihypertensive dihydropyridines lower Aß accumulation by targeting both the
production and the clearance of Aß across the blood-brain barrier.
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Molecular medicine (Cambridge, Mass.) 2011;17(3-4):149-62.
9.
2011
Pancham Bakshi; Elaina Margenthaler; Jon Reed; Fiona Crawford; Michael Mullan
Depletion of CXCR2 inhibits ?-secretase activity and amyloid-ß production in a murine model of
Alzheimer's disease.
Cytokine 2011;53(2):163-9.
10.
2011
Daniel Paris; Venkat Mathura; Ghania Ait-Ghezala; David Beaulieu-Abdelahad; Nikunj Patel;
Corbin Bachmeier; Michael Mullan
Flavonoids lower Alzheimer's Aß production via an NF?B dependent mechanism.
Bioinformation 2011;6(6):229-36.
11.
2011
Cheryl A Luis; Laila Abdullah; Ghania Ait-Ghezala; Benoit Mouzon; Andrew P Keegan; Fiona
Crawford; Michael Mullan
Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum ß-Amyloid.
International journal of Alzheimer's disease 2011;2011():786264.
12.
2010
Corbin Bachmeier; Michael Mullan ; Daniel Paris
Characterization and use of human brain microvascular endothelial cells to examine ß-amyloid
exchange in the blood-brain barrier.
Cytotechnology 2010;62(6):519-29.
13.
2010
Daniel Paris; Nowel Ganey; Magdalena Banasiak; Vincent Laporte; Nikunj Patel; Myles Michael
Mullan ; Susan F Murphy; Gi-Taek Yee; Corbin Bachmeier; Christopher Ganey; et al.
Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's
disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
2010;30(34):11251-8.
14.
2010
S Ferguson; B Mouzon; G Kayihan; M Wood; F Poon; S Doore; V Mathura; J Humphrey; B O'Steen; R
Hayes; et al.
Apolipoprotein E genotype and oxidative stress response to traumatic brain injury.
Neuroscience 2010;168(3):811-9.
15.
2010
Daniel Paris; Nowell J Ganey; Vincent Laporte; Nikunj S Patel; David Beaulieu-Abdelahad; Corbin
Bachmeier; Amelia March; Ghania Ait-Ghezala; Michael J Michael Mullan
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's
disease.
Journal of neuroinflammation 2010;7():17.
16.
2010
Nikunj S Patel; Venkatarajan S Mathura; Corbin Bachmeier; David Beaulieu-Abdelahad; Vincent
Laporte; Ophelia Weeks; Michael Mullan ; Daniel Paris
Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling
via direct interaction with VEGFR-2.
Journal of neurochemistry 2010;112(1):66-76.
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17.
2010
Venkatarajan S Mathura; Nikunj Patel; Corbin Bachmeier; Michael Mullan ; Daniel Paris
A 3D-QSAR model based screen for dihydropyridine-like compound library to identify inhibitors
of amyloid beta (Aß) production.
Bioinformation 2010;5(3):122-7.
18.
2009
Pancham Bakshi; Chao Jin; Pierre Broutin; Beniam Berhane; Jon Reed; Michael Mullan
Structural optimization of a CXCR2-directed antagonist that indirectly inhibits gamma-secretase
and reduces Abeta.
Bioorganic & medicinal chemistry 2009;17(23):8102-12.
19.
2009
Laila Abdullah; Cheryl Luis; Daniel Paris; Benoit Mouzon; Ghania Ait-Ghezala; Andrew P Keegan;
Duolao Wang; Fiona Crawford; Michael Mullan
Serum Abeta levels as predictors of conversion to mild cognitive impairment/Alzheimer disease
in an ADAPT subcohort.
Molecular medicine (Cambridge, Mass.) 2009;15(11-12):432-7.
20.
2009
Claude-Henry Volmar; Ghania Ait-Ghezala; Jeremy Frieling; Ophelia I Weeks; Michael J Michael
Mullan
CD40/CD40L interaction induces Abeta production and increases gamma-secretase activity
independently of tumor necrosis factor receptor associated factor (TRAF) signaling.
Experimental cell research 2009;315(13):2265-74.
21.
2009
F Crawford; M Wood; S Ferguson; V Mathura; P Gupta; J Humphrey; B Mouzon; V Laporte; E
Margenthaler; B O'Steen; et al.
Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury.
Neuroscience 2009;159(4):1349-62.
22.
2009
Cheryl A Luis; Laila Abdullah; Daniel Paris; Amita Quadros; Myles Michael Mullan ; Benoit
Mouzon; Ghania Ait-Ghezala; Fiona Crawford; Michael Mullan
Serum beta-amyloid correlates with neuropsychological impairment.
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition
2009;16(2):203-18.
23.
2009
Laila Abdullah; Cheryl Luis; Daniel Paris; Ghania Ait-ghezala; Benoit Mouzon; Elizabeth Allen;
Julia Parrish; Myles A Michael Mullan ; Scott Ferguson; Marcie Wood; et al.
High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease
patients.
Molecular medicine (Cambridge, Mass.) 2009;15(3-4):95-100.
24.
2009
Cheryl A Luis; Andrew P Keegan; Michael Mullan
Cross validation of the Montreal Cognitive Assessment in community dwelling older adults
residing in the Southeastern US.
International journal of geriatric psychiatry 2009;24(2):197-201.
25.
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2009
Venkatarajan S Mathura; Daniel Paris; Michael J Michael Mullan
A novel physico-chemical property based model for studying the effects of mutation on the
aggregation of peptides.
Protein and peptide letters 2009;16(8):991-8.
26.
2008
Pancham Bakshi; Elaina Margenthaler; Vincent Laporte; Fiona Crawford; Michael Mullan
Novel role of CXCR2 in regulation of gamma-secretase activity.
ACS chemical biology 2008;3(12):777-89.
27.
2008
Ghania Ait-ghezala; Laila Abdullah; Claude-Henry Volmar; Daniel Paris; Cheryl A Luis; Amita
Quadros; Benoit Mouzon; Myles A Michael Mullan ; Andrew P Keegan; Julia Parrish; et al.
Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's
disease.
Cytokine 2008;44(2):283-7.
28.
2008
Vincent Laporte; Ghania Ait-Ghezala; Claude-Henry Volmar; Christopher Ganey; Nowell Ganey;
Marcie Wood; Michael Mullan
CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice.
Brain research 2008;1231():132-42.
29.
2008
Michael J Michael Mullan ; Hanna Magowan; Colin D Weir
Femoral artery necrosis due to parenteral intravascular drug misuse: a case report and
literature review.
The Ulster medical journal 2008;77(3):203-4.
30.
2008
Barbara K Martin; Christine Szekely; Jason Brandt; Steven Piantadosi; John C S Breitner;
Suzanne Craft; Denis Evans; Robert Green; Michael Mullan
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial
(ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
Archives of neurology 2008;65(7):896-905.
31.
2008
Claude-Henry Volmar; Ghania Ait-Ghezala; Jeremy Frieling; Daniel Paris; Michael J Michael Mullan
The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta)
production.
Cytokine 2008;42(3):336-44.
32.
2008
Nikunj S Patel; Amita Quadros; Steven Brem; Marguerite Wotoczek-Obadia; Venkatarajan S Mathura;
Vincent Laporte; Michael Mullan ; Daniel Paris
Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide.
Amyloid : the international journal of experimental and clinical investigation : the official
journal of the International Society of Amyloidosis 2008;15(1):5-19.
33.
2008
Michael J Michael Mullan ; Julie L Scoffield; Pawan K Rajpal
Appendicectomy complicated by Addisons disease.
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The Ulster medical journal 2008;77(1):58-9.
34.
2007
Fiona C Crawford; Marcie Wood; Scott Ferguson; Venkatarajan S Mathura; Brandon Faza; Sarah
Wilson; Tao Fan; Barbara O'Steen; Ghania Ait-Ghezala; Ronald Hayes; et al.
Genomic analysis of response to traumatic brain injury in a mouse model of Alzheimer's disease
(APPsw).
Brain research 2007;1185():45-58.
35.
2007
Laila Abdullah; Daniel Paris; Cheryl Luis; Amita Quadros; Julia Parrish; Luis Valdes; Andrew P
Keegan; Venkatarajan Mathura; Fiona Crawford; Michael Mullan
The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels.
Neuroscience letters 2007;428(2-3):53-8.
36.
2007
Daniel Paris; Nikunj Patel; Amita Quadros; Monica Linan; Pancham Bakshi; Ghania Ait-Ghezala;
Michael Mullan
Inhibition of Abeta production by NF-kappaB inhibitors.
Neuroscience letters 2007;415(1):11-6.
37.
2007
Ghania Ait-Ghezala; Claude-Henry Volmar; Jeremy Frieling; Daniel Paris; Miles Tweed; Pancham
Bakshi; Michael Mullan
CD40 promotion of amyloid beta production occurs via the NF-kappaB pathway.
The European journal of neuroscience 2007;25(6):1685-95.
38.
2007
H Fai Poon; Laila Abdullah; Myles A Michael Mullan ; Michael J Michael Mullan ; Fiona C Crawford
Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells.
Neurochemistry international 2007;50(1):69-73.
39.
2007
Timothy A Crowell; Cheryl A Luis; David E Cox; Michael Mullan
Neuropsychological comparison of Alzheimer's disease and dementia with lewy bodies.
Dementia and geriatric cognitive disorders 2007;23(2):120-5.
40.
2007
H Fai Poon; Laila Abdullah; Jon Reed; Sarah M Doore; Cyndi Laird; Venkat Mathura; Michael
Mullan ; Fiona Crawford
Improving image analysis in 2DGE-based redox proteomics by labeling protein carbonyl with
fluorescent hydroxylamine.
Biological procedures online 2007;9():65-72.
41.
2007
Venkatarajan S Mathura; Mahendiranath Rangareddy; Pankaj Gupta; Michael Mullan
CliniProteus: A flexible clinical trials information management system.
Bioinformation 2007;2(4):163-5.
42.
2006
Fiona C Crawford; Marcie L Wood; Sarah E Wilson; Venkatarajan S Mathura; Tyler R Hollen; Freya
Geall; Deepak N Kolippakkam; Michael J Michael Mullan
Cocaine induced inflammatory response in human neuronal progenitor cells.
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Journal of neurochemistry 2006;97(3):662-74.
43.
2006
Laila Abdullah; Ghania Ait-Ghezala; Fiona Crawford; Timothy A Crowell; Warren W Barker; Ranjan
Duara; Michael Mullan
The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease.
Neuroscience letters 2006;395(3):240-3.
44.
2006
Timothy A Crowell; Juno Paramadevan; Laila Abdullah; Michael Mullan
Beneficial effect of cholinesterase inhibitor medications on recognition memory performance in
mild to moderate Alzheimer's disease: preliminary findings.
Journal of geriatric psychiatry and neurology 2006;19(1):13-5.
45.
2006
Vincent Laporte; Ghania Ait-Ghezala; Claude-Henry Volmar; Michael Mullan
CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models.
Journal of neuroinflammation 2006;3():3.
46.
2006
Amy R Borenstein; James A Mortimer; Yougui Wu; Fern M Jureidini-Webb; M Daniele Fallin; Brent J
Small; Michael Mullan ; Fiona C Crawford
Apolipoprotein E and cognition in community-based samples of African Americans and Caucasians.
Ethnicity & disease 2006;16(1):9-15.
47.
2005
Ghania Ait-Ghezala; Venkatarajan S Mathura; Vincent Laporte; Amita Quadros; Daniel Paris;
Nikunj Patel; Claude-Henry Volmar; Deepak Kolippakkam; Fiona Crawford; Mike Michael Mullan
Genomic regulation after CD40 stimulation in microglia: relevance to Alzheimer's disease.
Brain research. Molecular brain research 2005;140(1-2):73-85.
48.
2005
Venkatarajan S Mathura; Daniel Paris; Ghania Ait-Ghezala; Amita Quadros; Nikunj S Patel; Deepak
N Kolippakkam; Claude-Henry Volmar; Michael J Michael Mullan
Model of Alzheimer's disease amyloid-beta peptide based on a RNA binding protein.
Biochemical and biophysical research communications 2005;332(2):585-92.
49.
2005
Daniel Paris; Ghania Ait-Ghezala; Venkatarajan S Mathura; Nikunj Patel; Amita Quadros; Vincent
Laporte; Mike Michael Mullan
Anti-angiogenic activity of the mutant Dutch A(beta) peptide on human brain microvascular
endothelial cells.
Brain research. Molecular brain research 2005;136(1-2):212-30.
50.
2005
Daniel Paris; Amita Quadros; Nikunj Patel; Anthony DelleDonne; James Humphrey; Michael Mullan
Inhibition of angiogenesis and tumor growth by beta and gamma-secretase inhibitors.
European journal of pharmacology 2005;514(1):1-15.
51.
2005
Terrence Town; Jun Tan; Richard A Flavell; Mike Michael Mullan
T-cells in Alzheimer's disease.
Neuromolecular medicine 2005;7(3):255-64.
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52.
2004
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Michael Mullan ; Ranjan Duara
No association between subjective memory complaints and apolipoprotein E genotype in
cognitively intact elderly.
International journal of geriatric psychiatry 2004;19(12):1131-9.
53.
2004
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Peter St George-Hyslop; Michael Mullan ;
Ranjan Duara
Apolipoprotein E polymorphism and age of onset for Alzheimer's disease in a bi-ethnic sample.
International psychogeriatrics / IPA 2004;16(3):317-26.
54.
2004
Daniel Paris; Nikunj Patel; Anthony DelleDonne; Amita Quadros; Robert Smeed; Michael Mullan
Impaired angiogenesis in a transgenic mouse model of cerebral amyloidosis.
Neuroscience letters 2004;366(1):80-5.
55.
2004
J Todd Roach; Claude-Henry Volmar; Samvid Dwivedi; Terrence Town; Robert Crescentini; Fiona
Crawford; Jun Tan; Michael Mullan
Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice.
Brain research 2004;1015(1-2):161-8.
56.
2004
Jiazhi Sun; Michelle A Blaskovich; Rishi K Jain; Frederic Delarue; Daniel Paris; Steven Brem;
Marguerite Wotoczek-Obadia; Qing Lin; Domenico Coppola; Kihang Choi; et al.
Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits
binding of vascular endothelial growth factor to its receptor.
Cancer research 2004;64(10):3586-92.
57.
2004
Ryan T Mott; Ghania Ait-Ghezala; Terrence Town; Takashi Mori; Martina Vendrame; Jin Zeng; Jared
Ehrhart; Michae Michael Mullan ; Jun Tan
Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine
production.
Glia 2004;46(4):369-79.
58.
2004
Daniel Paris; Amita Quadros; James Humphrey; Nikunj Patel; Robert Crescentini; Fiona Crawford;
Michael Mullan
Nilvadipine antagonizes both Abeta vasoactivity in isolated arteries, and the reduced cerebral
blood flow in APPsw transgenic mice.
Brain research 2004;999(1):53-61.
59.
2004
Daniel Paris; Kirk Townsend; Amita Quadros; James Humphrey; Jiazhi Sun; Steven Brem; Marguerite
Wotoczek-Obadia; Anthony DelleDonne; Nikunj Patel; Demian F Obregon; et al.
Inhibition of angiogenesis by Abeta peptides.
Angiogenesis 2004;7(1):75-85.
60.
2003
Amita Quadros; Nikunj Patel; Robert Crescentini; Fiona Crawford; Daniel Paris; Michael Mullan
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Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw
transgenic mice.
Neuroscience letters 2003;353(1):66-8.
61.
2003
Daniel Paris; James Humphrey; Amita Quadros; Nikunj Patel; Robert Crescentini; Fiona Crawford;
Michael Mullan
Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model
of Alzheimer's disease: role of inflammation.
Neurological research 2003;25(6):642-51.
62.
2003
Fiona C Crawford; Ghania Ait-Ghezala; Mark Morris; Maxine J Sutcliffe; Robert A Hauser; Archie
A Silver; Michael J Michael Mullan
Translocation breakpoint in two unrelated Tourette syndrome cases, within a region previously
linked to the disorder.
Human genetics 2003;113(2):154-61.
63.
2002
Jun Tan; Terrence Town; Fiona Crawford; Takashi Mori; Anthony DelleDonne; Robert Crescentini;
Demian Obregon; Richard A Flavell; Michael J Michael Mullan
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.
Nature neuroscience 2002;5(12):1288-93.
64.
2002
Terrence Town; Martina Vendrame; Anant Patel; Daniel Poetter; Anthony DelleDonne; Takashi Mori;
Robert Smeed; Fiona Crawford; Thomas Klein; Jun Tan; et al.
Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42).
Journal of neuroimmunology 2002;132(1-2):49-59.
65.
2002
Jun Tan; Terrence Town; Laila Abdullah; Yajaun Wu; Andon Placzek; Brent Small; Jodi Kroeger;
Fiona Crawford; Dan Richards; Michael Mullan
CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease.
Journal of neuroimmunology 2002;132(1-2):164-72.
66.
2002
K P Townsend; D Obregon; A Quadros; N Patel; Ch Volmar; D Paris; M Michael Mullan
Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature.
Annals of the New York Academy of Sciences 2002;977():65-76.
67.
2002
Robert L Yuspeh; Rodney D Vanderploeg; Timothy A Crowell; Michael Mullan
Differences in executive functioning between Alzheimer's disease and subcortical ischemic
vascular dementia.
Journal of clinical and experimental neuropsychology 2002;24(6):745-54.
68.
2002
Daniel Paris; Kirk P Townsend; Demian F Obregon; James Humphrey; Michael Mullan
Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain.
Prostaglandins & other lipid mediators 2002;70(1-2):1-12.
69.
2002
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Terrence Town; Joseph Zolton; Reed Shaffner; Billy Schnell; Robert Crescentini; Yajuan Wu; Jin
Zeng; Anthony DelleDonne; Demian Obregon; Jun Tan; et al.
p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro.
Journal of neuroscience research 2002;69(3):362-72.
70.
2002
Jun Tan; Terrence Town; Mike Michael Mullan
CD40-CD40L interaction in Alzheimer's disease.
Current opinion in pharmacology 2002;2(4):445-51.
71.
2002
G Ait-Ghezala; L Abdullah; R Crescentini; F Crawford; T Town; S Singh; D Richards; R Duara; M
Michael Mullan
Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample.
Neuroscience letters 2002;325(2):87-90.
72.
2002
F C Crawford; R D Vanderploeg; M J Freeman; S Singh; M Waisman; L Michaels; L Abdullah; D
Warden; R Lipsky; A Salazar; et al.
APOE genotype influences acquisition and recall following traumatic brain injury.
Neurology 2002;58(7):1115-8.
73.
2002
Daniel Paris; Kirk P Townsend; James Humphrey; Demian F Obregon; Kiyoko Yokota; Michael Mullan
Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and
inflammation in rat aortae.
Atherosclerosis 2002;161(2):293-9.
74.
2002
Jun Tan; Terrence Town; Takashi Mori; Demian Obregon; Yajuan Wu; Anthony DelleDonne; Amyn
Rojiani; Fiona Crawford; Richard A Flavell; Mike Michael Mullan
CD40 is expressed and functional on neuronal cells.
The EMBO journal 2002;21(4):643-52.
75.
2002
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Michael Mullan ; Ranjan Duara
Apolipoprotein E polymorphism and cognitive impairment in a bi-ethnic community-dwelling
elderly sample.
Alzheimer disease and associated disorders 2002;16(1):8-14.
76.
2002
J A Schinka; T Town; L Abdullah; F C Crawford; P I Ordorica; E Francis; P Hughes; A B Graves; J
A Mortimer; M Michael Mullan
A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and
other substances.
Molecular psychiatry 2002;7(2):224-8.
77.
2002
Dylan G Harwood; Warren W Barker; Raymond L Ownby; Michael Mullan ; Ranjan Duara
Apolipoprotein E genotype and cognitive impairment in community-dwelling black older adults.
International journal of psychiatry in medicine 2002;32(1):55-67.
78.
2001
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C Russ; J F Powell; J Zhao; M Baker; M Hutton; F Crawford; M Michael Mullan ; G Roks; M Cruts;
S Lovestone
The microtubule associated protein Tau gene and Alzheimer's disease--an association study and
meta-analysis.
Neuroscience letters 2001;314(1-2):92-6.
79.
2001
T Town; J Tan; M Michael Mullan
CD40 signaling and Alzheimer's disease pathogenesis.
Neurochemistry international 2001;39(5-6):371-80.
80.
2001
T Mori; D Paris; T Town; A M Rojiani; D L Sparks; A Delledonne; F Crawford; L I Abdullah; J A
Humphrey; D W Dickson; et al.
Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic
APP(SW) mice.
Journal of neuropathology and experimental neurology 2001;60(8):778-85.
81.
2001
T Town; J Tan; N Sansone; D Obregon; T Klein; M Michael Mullan
Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42.
Neuroscience letters 2001;307(2):101-4.
82.
2001
F C Crawford; M J Freeman; J A Schinka; M D Morris; L I Abdullah; D Richards; S Sevush; R
Duara; M J Michael Mullan
Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase
gene.
Experimental neurology 2001;167(2):456-9.
83.
2000
T Town; J Schinka; J Tan; M Michael Mullan
The opioid receptor system and alcoholism: a genetic perspective.
European journal of pharmacology 2000;410(2-3):243-248.
84.
2000
J Tan; T Town; M Michael Mullan
CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42
MAPK pathway.
The Journal of biological chemistry 2000;275(47):37224-31.
85.
2000
J Tan; T Town; T Mori; Y Wu; M Saxe; F Crawford; M Michael Mullan
CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42
mitogen-activated protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience
2000;20(20):7587-94.
86.
2000
F C Crawford; M J Freeman; J A Schinka; L I Abdullah; M Gold; R Hartman; K Krivian; M D Morris;
D Richards; R Duara; et al.
A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease.
Neurology 2000;55(6):763-8.
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87.
2000
D Paris; T Town; J Humphrey; K Yokota; M Michael Mullan
Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory
pathway.
Biochemical and biophysical research communications 2000;274(2):553-8.
88.
2000
A Tandon; E Rogaeva; M Michael Mullan ; P H St George-Hyslop
Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins.
Current opinion in neurology 2000;13(4):377-84.
89.
2000
F C Crawford; M J Freeman; J Schinka; L I Abdullah; D Richards; S Sevush; R Duara; M J Michael
Mullan
The genetic association between Cathepsin D and Alzheimer's disease.
Neuroscience letters 2000;289(1):61-5.
90.
2000
B J Small; A B Graves; C L McEvoy; F C Crawford; M Michael Mullan ; J A Mortimer
Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging?
Neurology 2000;54(11):2082-8.
91.
2000
Y M Kuo; F Crawford; M Michael Mullan ; T A Kokjohn; M R Emmerling; R O Weller; A E Roher
Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to
amyloid accumulation in Alzheimer's disease.
Molecular medicine (Cambridge, Mass.) 2000;6(5):430-9.
92.
2000
F Crawford; M Freeman; L Abdullah; J Schinka; M Gold; R Duara; M Michael Mullan
No association between the NOS3 codon 298 polymorphism and Alzheimer's disease in a sample from
the United States.
Annals of neurology 2000;47(5):687.
93.
2000
D Paris; T Town; T Parker; J Humphrey; M Michael Mullan
A beta vasoactivity: an inflammatory reaction.
Annals of the New York Academy of Sciences 2000;903():97-109.
94.
2000
Z Suo; G Su; A Placzek; A Kundtz; J Humphrey; F Crawford; M Michael Mullan
A beta vasoactivity in vivo.
Annals of the New York Academy of Sciences 2000;903():156-63.
95.
2000
D Paris; T Town; T Parker; J Humphrey; M Michael Mullan
beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating
agents.
Annals of the New York Academy of Sciences 2000;903():446-50.
96.
2000
D Paris; T Town; T Mori; T A Parker; J Humphrey; M Michael Mullan
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Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway.
Neurobiology of aging 2000;21(2):183-97.
97.
2000
F Crawford; L Abdullah; J Schinka; Z Suo; M Gold; R Duara; M Michael Mullan
Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease.
Neuroscience letters 2000;280(3):215-9.
98.
2000
D Paris; T Town; M Michael Mullan
Novel strategies for opposing murine microglial activation.
Neuroscience letters 2000;278(1-2):5-8.
99.
2000
S Sevush; G Peruyera; F Crawford; M Michael Mullan
Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with
Alzheimer's disease.
The American journal of geriatric psychiatry : official journal of the American Association for
Geriatric Psychiatry 2000;8(3):254-6.
100.
2000
D G Harwood; W W Barker; R L Ownby; M J Michael Mullan ; R Duara
Family history of dementia and current depression in nondemented community-dwelling older adults.
Journal of geriatric psychiatry and neurology 2000;13(2):65-71.
101.
1999
J Tan; T Town; D Paris; T Mori; Z Suo; F Crawford; M P Mattson; R A Flavell; M Michael Mullan
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.
Science (New York, N.Y.) 1999;286(5448):2352-5.
102.
1999
J Tan; T Town; M Saxe; D Paris; Y Wu; M Michael Mullan
Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent
TNF-alpha production that is opposed by TGF-beta 1 and IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6614-21.
103.
1999
T Town; L Abdullah; F Crawford; J Schinka; P I Ordorica; E Francis; P Hughes; R Duara; M
Michael Mullan
Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency.
American journal of medical genetics 1999;88(5):458-61.
104.
1999
T Town; D Paris; T A Parker; A Kundtz; J Tan; R Duara; M Gold; F Crawford; M Michael Mullan
Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G
protein beta3, either independently or interactively with apolipoprotein E.
American journal of medical genetics 1999;88(5):465-8.
105.
1999
J Tan; T Town; Z Suo; Y Wu; S Song; A Kundtz; J Kroeger; J Humphrey; F Crawford; M Michael
Mullan
Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides.
Brain research bulletin 1999;50(2):143-8.
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106.
1999
J Tan; T Town; A Placzek; A Kundtz; H Yu; M Michael Mullan
Bcl-X(L) inhibits apoptosis and necrosis produced by Alzheimer's beta-amyloid1-40 peptide in
PC12 cells.
Neuroscience letters 1999;272(1):5-8.
107.
1999
D L King; G W Arendash; F Crawford; T Sterk; J Menendez; M J Michael Mullan
Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for
Alzheimer's disease.
Behavioural brain research 1999;103(2):145-62.
108.
1999
F Crawford; T Town; M Freeman; J Schinka; M Gold; R Duara; M Michael Mullan
The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control
sample.
Neuroscience letters 1999;270(3):133-6.
109.
1999
G W Arendash; G C Su; F C Crawford; K B Bjugstad; M Michael Mullan
Intravascular beta-amyloid infusion increases blood pressure: implications for a vasoactive
role of beta-amyloid in the pathogenesis of Alzheimer's disease.
Neuroscience letters 1999;268(1):17-20.
110.
1999
J Tan; T Town; D Paris; A Placzek; T Parker; F Crawford; H Yu; J Humphrey; M Michael Mullan
Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis.
Journal of neuroimmunology 1999;97(1-2):77-85.
111.
1999
F Crawford; M Freeman; T Town; D Fallin; M Gold; R Duara; M Michael Mullan
No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic
or population based samples.
Neuroscience letters 1999;266(3):193-6.
112.
1999
D Paris; T Town; T A Parker; J Tan; J Humphrey; F Crawford; M Michael Mullan
Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in
microglia by a cGMP-dependent mechanism.
Experimental neurology 1999;157(1):211-21.
113.
1999
D G Harwood; W W Barker; R L Ownby; M Michael Mullan ; R Duara
Factors associated with depressive symptoms in non-demented community-dwelling elderly.
International journal of geriatric psychiatry 1999;14(5):331-7.
114.
1999
G C Su; G W Arendash; R N Kalaria; K B Bjugstad; M Michael Mullan
Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate
CNS glial cells and induce peripheral hemorrhage.
Brain research 1999;818(1):105-17.
115.
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1999
D G Harwood; W W Barker; D A Loewenstein; R L Ownby; P St George-Hyslop; M Michael Mullan ; R
Duara
A cross-ethnic analysis of risk factors for AD in white Hispanics and white non-Hispanics.
Neurology 1999;52(3):551-6.
116.
1999
P N Pompl; M J Michael Mullan ; K Bjugstad; G W Arendash
Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive
impairment in the APP(SW) transgenic mouse model for Alzheimer's disease.
Journal of neuroscience methods 1999;87(1):87-95.
117.
1998
Z Suo; J Humphrey; A Kundtz; F Sethi; A Placzek; F Crawford; M Michael Mullan
Soluble Alzheimers beta-amyloid constricts the cerebral vasculature in vivo.
Neuroscience letters 1998;257(2):77-80.
118.
1998
W Barker; D Harwood; R Duara; M Michael Mullan ; D Fallin; P S Hyslop; E Rogaeva; Y Song
The APOE-epsilon4 allele and Alzheimer disease among African Americans, Hispanics, and whites.
JAMA : the journal of the American Medical Association 1998;280(19):1661-2; author reply 1663.
119.
1998
D Paris; T Town; T A Parker; J Humphrey; M Michael Mullan
Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by
Alzheimer's beta-amyloid peptide.
Neuroscience letters 1998;256(2):73-6.
120.
1998
F Crawford; C Soto; Z Suo; C Fang; T Parker; A Sawar; B Frangione; M Michael Mullan
Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational
intermediate.
FEBS letters 1998;436(3):445-8.
121.
1998
Z Suo; J Tan; A Placzek; F Crawford; C Fang; M Michael Mullan
Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the
roles of cytokines and CD40.
Brain research 1998;807(1-2):110-7.
122.
1998
T Town; D Paris; D Fallin; R Duara; W Barker; M Gold; F Crawford; M Michael Mullan
The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease:
independent risk and linkage disequilibrium with the known APOE polymorphism.
Neuroscience letters 1998;252(2):95-8.
123.
1998
R T Zori; J L Gardner; J Zhang; M J Michael Mullan ; R Shah; A R Osborn; H Houlden; M R
Wallace; S Roberts; T P Yang
Newly described form of X-linked arthrogryposis maps to the long arm of the human X chromosome.
American journal of medical genetics 1998;78(5):450-4.
124.
1998
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D Paris; T A Parker; T Town; Z Suo; C Fang; J Humphrey; F Crawford; M Michael Mullan
Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40
peptide.
Experimental neurology 1998;152(1):116-22.
125.
1998
F Crawford; D Fallin; Z Suo; L Abdullah; M Gold; A Gauntlett; R Duara; M Michael Mullan
The butyrylcholinesterase gene is neither independently nor synergistically associated with
late-onset AD in clinic- and community-based populations.
Neuroscience letters 1998;249(2-3):115-8.
126.
1998
F Crawford; Z Suo; C Fang; M Michael Mullan
Characteristics of the in vitro vasoactivity of beta-amyloid peptides.
Experimental neurology 1998;150(1):159-68.
127.
1997
F Crawford; Z Suo; C Fang; A Sawar; G Su; G Arendash; M Michael Mullan
The vasoactivity of A beta peptides.
Annals of the New York Academy of Sciences 1997;826():35-46.
128.
1997
G C Su; G W Arendash; R N Kalaria; M J Michael Mullan
Long-term venous A beta 1-40 infusion in rats causes lung hemorrhage and brain perivascular
gliosis.
Annals of the New York Academy of Sciences 1997;826():440-6.
129.
1997
F Crawford; Z Suo; C Fang; M Michael Mullan
beta-Amyloid peptides and enhancement of vasoconstriction by endothelin-1.
Annals of the New York Academy of Sciences 1997;826():461-2.
130.
1997
D Fallin; A Kundtz; T Town; A C Gauntlett; R Duara; W Barker; F Crawford; M Michael Mullan
No association between the low density lipoprotein receptor-related protein (LRP) gene and
late-onset Alzheimer's disease in a community-based sample.
Neuroscience letters 1997;233(2-3):145-7.
131.
1997
X Cai; D Fallin; J Stanton; P Scibelli; R Duara; F Crawford; M Michael Mullan
APOE is linked to Alzheimer's disease in a large pedigree.
American journal of medical genetics 1997;74(4):365-9.
132.
1997
T Town; D Fallin; F Crawford; S Walsh; R Solomon; M Michael Mullan
Lack of association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and chronic
schizophrenia.
American journal of medical genetics 1997;74(4):451-2.
133.
1997
Z Suo; C Fang; F Crawford; M Michael Mullan
Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial
toxicity.
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Brain research 1997;762(1-2):144-52.
134.
1997
D Fallin; S Reading; J Schinka; J Hoyne; P Scibelli; M Gold; F Crawford; M Michael Mullan
No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's
disease.
American journal of medical genetics 1997;74(2):192-4.
135.
1997
X Cai; J Stanton; D Fallin; J Hoyne; R Duara; M Gold; S Sevush; P Scibelli; F Crawford; M
Michael Mullan
No association between the intronic presenilin-1 polymorphism and Alzheimer's disease in clinic
and population-based samples.
American journal of medical genetics 1997;74(2):202-3.
136.
1997
D Fallin; A C Gauntlett; P Scibelli; X Cai; R Duara; M Gold; F Crawford; M Michael Mullan
No association between the very low density lipoprotein receptor gene and late-onset
Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and
clinic samples.
Genetic epidemiology 1997;14(3):299-305.
137.
1996
M Michael Mullan ; P Scibelli; R Duara; D Fallin; M Gold; J Schinka; J Hoyne; A Osborne; S
Sevush; F Crawford
Familial and population-based studies of apolipoprotein E and Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;802():16-26.
138.
1996
F Crawford; J Hoyne; X Cai; A Osborne; D Poston; J Zaglul; N Dajani; S Walsh; R Bradley; R
Solomon; et al.
Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.
American journal of medical genetics 1996;67(5):483-4.
139.
1996
T Thomas; G Thomas; C McLendon; T Sutton; M Michael Mullan
beta-Amyloid-mediated vasoactivity and vascular endothelial damage.
Nature 1996;380(6570):168-71.
140.
1995
S E Poduslo; D Riggs; J Schwankhaus; A Osborne; F Crawford; M Michael Mullan
Association of apolipoprotein E but not B with Alzheimer's disease.
Human genetics 1995;96(5):597-600.
141.
1995
F Crawford; J Hoyne; P Diaz; A Osborne; J Dorotheo; D Sheehan; M Michael Mullan
Occurrence of the Cys311 DRD2 variant in a pedigree multiply affected with panic disorder.
American journal of medical genetics 1995;60(4):332-4.
142.
1995
C Bennett; F Crawford; A Osborne; P Diaz; J Hoyne; R Lopez; P Roques; R Duara; M Rossor; M
Michael Mullan
Evidence that the APOE locus influences rate of disease progression in late onset familial
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Alzheimer's Disease but is not causative.
American journal of medical genetics 1995;60(1):1-6.
143.
1995
M Michael Mullan ; C Bennett; C Figueredo; D Hughes; R Mant; M Owen; A Warren; M McInnis; A
Marshall; P Lantos
Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14.
American journal of medical genetics 1995;60(1):44-52.
144.
1994
M Michael Mullan ; F Crawford
The molecular genetics of Alzheimer's disease.
Molecular neurobiology 1994;9(1-3):15-22.
145.
1994
M Michael Mullan ; F Crawford; J Buchanan
Technical feasibility of genetic testing for Alzheimer's disease.
Alzheimer disease and associated disorders 1994;8(2):102-15.
146.
1993
M Michael Mullan ; H Houlden; F Crawford; A Kennedy; P Rogues; M Rossor
Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology.
American journal of medical genetics 1993;48(3):129-30.
147.
1993
M Michael Mullan ; F Crawford
Genetic and molecular advances in Alzheimer's disease.
Trends in neurosciences 1993;16(10):398-403.
148.
1993
M Michael Mullan ; S Tsuji; T Miki; T Katsuya; S Naruse; K Kaneko; T Shimizu; T Kojima; I
Nakano; T Ogihara
Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val-->Ile mutation
in the amyloid precursor protein gene.
Neurobiology of aging 1993;14(5):407-19.
149.
1993
H Houlden; F Crawford; M Rossor; M Michael Mullan
Screening for the APP codon 670/671 mutations in Alzheimer's disease.
Neuroscience letters 1993;154(1-2):161-2.
150.
1993
H Houlden; M Michael Mullan
Alzheimer's disease aetiology: amyloid and chromosome 14.
British journal of hospital medicine 1993;49(8):535-6.
151.
1993
A M Kennedy; S Newman; A McCaddon; J Ball; P Roques; M Michael Mullan ; J Hardy; M C
Chartier-Harlin; R S Frackowiak; E K Warrington
Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor
protein gene (amyloid precursor protein 717 valine-->glycine).
Brain : a journal of neurology 1993;116 ( Pt 2)():309-24.
152.
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1993
J Brown; S Gydesen; S A Sorensen; A Brun; S Smith; H Houlden; R Twells; M Michael Mullan ; M
Rossor; J Collinge
Genetic characterization of a familial non-specific dementia originating in Jutland, Denmark.
Journal of the neurological sciences 1993;114(2):138-43.
153.
1992
M Michael Mullan ; H Houlden; M Windelspecht; L Fidani; C Lombardi; P Diaz; M Rossor; R Crook;
J Hardy; K Duff
A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal
to the alpha 1-antichymotrypsin gene.
Nature genetics 1992;2(4):340-2.
154.
1992
M Michael Mullan
Familial Alzheimer's disease: second gene locus located.
BMJ (Clinical research ed.) 1992;305(6862):1108-9.
155.
1992
K J Johnson; T Sander; A A Hicks; A van Marle; D Janz; M J Michael Mullan ; B P Riley; M G
Darlison
Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to
distal 5q by linkage analysis.
Genomics 1992;14(3):745-8.
156.
1992
J Hardy; M Michael Mullan
Alzheimer's disease. In search of the soluble.
Nature 1992;359(6393):268-9.
157.
1992
M Michael Mullan ; F Crawford; K Axelman; H Houlden; L Lilius; B Winblad; L Lannfelt
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of
beta-amyloid.
Nature genetics 1992;1(5):345-7.
158.
1992
L Fidani; K Rooke; M C Chartier-Harlin; D Hughes; R Tanzi; M Michael Mullan ; P Roques; M
Rossor; J Hardy; A Goate
Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor
protein gene in familial Alzheimer's disease: identification of a further family with APP717
Val-->Ile.
Human molecular genetics 1992;1(3):165-8.
159.
1992
J Collinge; J Brown; J Hardy; M Michael Mullan ; M N Rossor; H Baker; T J Crow; R Lofthouse; M
Poulter; R Ridley
Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features.
Brain : a journal of neurology 1992;115 ( Pt 3)():687-710.
160.
1992
F Crawford; M C Chartier-Harlin; M Michael Mullan ; J Hardy; A Delacourte; G Arnott
Alzheimer's--a correction.
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Nature 1992;356(6368):390.
161.
1992
P L Lantos; P J Luthert; D Hanger; B H Anderton; M Michael Mullan ; M Rossor
Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and
sporadic Alzheimer's disease have the same cytoskeletal pathology.
Neuroscience letters 1992;137(2):221-4.
162.
1992
J Hardy; M C Chartier-Harlin; M Michael Mullan
Alzheimer disease: the new agenda.
American journal of human genetics 1992;50(3):648-51.
163.
1992
C L Katona; M Michael Mullan ; C Taylor
Depressive disorders and organic brain disorders: validation of the depressive signs scale.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():169A-170A.
164.
1991
F Crawford; J Hardy; M Michael Mullan ; A Goate; D Hughes; L Fidani; P Roques; M Rossor; M C
Chartier-Harlin
Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with
early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence.
Neuroscience letters 1991;133(1):1-2.
165.
1991
R C Pearson; M Michael Mullan ; J Hardy; P J Harrison
Nicotine intake and Alzheimer's disease.
BMJ (Clinical research ed.) 1991;303(6798):361.
166.
1991
M C Chartier-Harlin; F Crawford; K Hamandi; M Michael Mullan ; A Goate; J Hardy; H Backhovens;
J J Martin; C V Broeckhoven
Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended
pedigrees with early onset Alzheimer's disease.
Neuroscience letters 1991;129(1):134-5.
167.
1991
D L Ewins; M N Rossor; J Butler; P K Roques; M J Michael Mullan ; A M McGregor
Association between autoimmune thyroid disease and familial Alzheimer's disease.
Clinical endocrinology 1991;35(1):93-6.
168.
1991
C M van Duijn; C van Broeckhoven; J A Hardy; A M Goate; M N Rossor; A Vandenberghe; J J Martin;
A Hofman; M J Michael Mullan
Evidence for allelic heterogeneity in familial early-onset Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1991;158():471-4.
169.
1991
M Michael Mullan
A genetic defect causing Alzheimer's disease.
British journal of hospital medicine 1991;45(3):131.
170.
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1991
A Goate; M C Chartier-Harlin; M Michael Mullan ; J Brown; F Crawford; L Fidani; L Giuffra; A
Haynes; N Irving; L James
Segregation of a missense mutation in the amyloid precursor protein gene with familial
Alzheimer's disease.
Nature 1991;349(6311):704-6.
171.
1991
M J Michael Mullan ; L Giuffra; J A Hardy; I Ovenstone; A R Haynes; L A James; R Williamson; P
J Newton; M J Owen; P Roques
Clinical and pathologic features of chromosome 21-linked familial Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;640():177-80.
172.
1991
J Brown; S Smith; A Brun; J Collinge; S Gydesen; J Hardy; M Michael Mullan ; A Goate
Genetic characterization of a novel familial dementia.
Annals of the New York Academy of Sciences 1991;640():181-3.
173.
1990
P H St George-Hyslop; J L Haines; L A Farrer; R Polinsky; C Van Broeckhoven; A Goate; D R
McLachlan; H Orr; A C Bruni; S Sorbi; et al.
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.
Nature 1990;347(6289):194-7.
174.
1990
J Clinton; P L Lantos; M Rossor; M Michael Mullan ; G W Roberts
Immunocytochemical confirmation of prion protein.
Lancet 1990;336(8713):515.
175.
1990
J Collinge; F Owen; M Poulter; M Leach; T J Crow; M N Rossor; J Hardy; M J Michael Mullan ; I
Janota; P L Lantos
Prion dementia without characteristic pathology.
Lancet 1990;336(8706):7-9.
176.
1990
S Hodgkinson; M J Michael Mullan ; H M Gurling
The role of genetic factors in the etiology of the affective disorders.
Behavior genetics 1990;20(2):235-50.
177.
1990
L A Farrer; R H Myers; L A Cupples; P H St George-Hyslop; T D Bird; M N Rossor; M J Michael
Mullan ; R Polinsky; L Nee; L Heston
Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for
heterogeneity.
Neurology 1990;40(3 Pt 1):395-403.
178.
1990
A M Goate; J A Hardy; M J Owen; A Haynes; L James; M Farrall; M J Michael Mullan ; P Roques; M
N Rossor
Genetics of Alzheimer's disease.
Advances in neurology 1990;51():197-8.
179.
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1990
M J Owen; M J Michael Mullan
Molecular genetic studies of manic-depression and schizophrenia.
Trends in neurosciences 1990;13(1):29-31.
180.
1989
J A Hardy; A M Goate; M J Owen; M J Michael Mullan ; M N Rossor; R C Pearson
Modelling the occurrence and pathology of Alzheimer's disease.
Neurobiology of aging 1989;10(5):429-31; discussion 446-8.
181.
1989
M J Michael Mullan ; R M Murray
The impact of molecular genetics on our understanding of the psychoses.
The British journal of psychiatry : the journal of mental science 1989;154():591-5.
182.
1989
A M Goate; A R Haynes; M J Owen; M Farrall; L A James; L Y Lai; M J Michael Mullan ; P Roques;
M N Rossor; R Williamson
Predisposing locus for Alzheimer's disease on chromosome 21.
Lancet 1989;1(8634):352-5.
183.
1989
J A Hardy; M J Owen; A M Goate; L A James; A R Haynes; M N Rossor; P Roques; M J Michael Mullan
Molecular genetics of Alzheimer's disease.
Biochemical Society transactions 1989;17(1):75-6.
184.
1986
M J Michael Mullan ; H M Gurling; B E Oppenheim; R M Murray
The relationship between alcoholism and neurosis: evidence from a twin study.
The British journal of psychiatry : the journal of mental science 1986;148():435-41.
-21-