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GENERAL INFO

TECHNICAL INFO

May 2020

Systemic lupus erythematosus (an autoimmune disease which may cause an in�ammation of internal organs), tingling or numbness in the hands or feet, insomnia, nightmares, memory loss, an increase in signs and symptoms of myasthenia gravis (muscle disorder), decreased sex drive, temporary short sightedness which may resolve when the treatment is stopped, detachment of the layer below the retina that contains the blood vessels following on from �ltration surgery which may cause visual disturbances, drooping of the eyelids (making the eye stay half closed), double vision, eyelid crusting, swelling of the cornea (with symptoms of visual disturbances), low pressure in the eye, ringing noises in your ear, low blood pressure, changes in the rhythm or speed of the heartbeat, oedema (�uid build-up), cerebral ischaemia (reduced blood supply to the brain), chest pain, forceful heartbeat that may be rapid or irregular (palpitations), heart attack, Raynaud’s phenomenon, swelling or coldness in the hands and feet and reduced circulation in the arms and legs, leg cramps and/or leg pain when walking (claudication), shortness of breath, impaired lung function, runny or stuffed nose, nosebleed, constriction of the airways in the lungs, cough, throat irritation, dry mouth, diarrhoea, contact dermatitis, hair loss, skin rash with white silvery coloured appearance (psoriasiform rash), Peyronie´s disease (which may cause a curvature of the penis). Like other topically applied ophthalmic drugs, dorzolamide and timolol (active substances of the medicinal product) are absorbed into the blood. This may cause similar side effects as seen with systemic beta-blocking agents and carbonic anhydrase inhibitors. Incidence of side effects after topical ophthalmic administration is lower than when medicines are, for example, taken by mouth or injected. Listed additional side effects include reactions seen within the class of beta-blockers when used for treating eye conditions.

Low blood glucose levels, hallucination, foreign body sensation in eye (feeling that there is something in your eye), heart failure, a type of heart rhythm disorder, shortness of breath, abdominal pain, vomiting, muscle pain not caused by exercise, sexual dysfunction.