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CERTIFICATE COURSE IN ADVANCED HOMOEOPATHY

Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic: Research Methodology

Time: 10.00 am – 5.00 pm

Part 1

Every branch is a science, art like Homeopathy

Research Methodology

Research: re- cherche, chercher-search

Careful scientific investigation

Art of scientific investigation

Systemic effort to gain new knowledge

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Methodology:

Analysis of principles of procedures, science of studying how research is to be carried out

But Ultimate aim is to serve Mankind and Benefit of Patients.

Aim of the research should be to do something new what we have not done earlier

We have opportunities, but do not want to take advantage of it

We have enough literature yet we don’t want to do it

So there may be some reason??

Or we feel it is difficult many a times or we don’t want to publish our records- that is the problem with Homeopathy we want to hide everything

My way of practicing I don’t want to disclose

What I give I don’t want to disclose

These are not the ideal clinical situations

If I am getting result in a particular method I should be open

I should not be worried whether it is a classical, non classical whatever it is. It should be driven by the result.

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If I am getting result with this particular method I should find out why I am getting it, if I am not getting, why I am not getting

All these are the meanings

How to do the research???

Analysis Principles & procedures

Why most of the researches done by the Homeopathic doctors or Homeopaths is rejected & not published, not accepted & not listened is because we don’t follow a methodology & publication & research.

See unless you do in a scientific way

If I cure 100 cases in my practice, it amounts nothing, unless I categorized it & scientifically show how I do it, the result has to be reproducible.

Somebody says I have cured Cancer!!!

OKAY

How many cases have you Cured??

If I sent you 100 cases out of it than how many cases you can cure it ----- That is what is important

One case doesn’t mean anything5 | P a g e

One can get Spontaneous remission that is what people say, so how you counter than??

So you can require a scientific methodology so that whatever you publish is acceptable by scientific community otherwise it remains between you & me. You say I have cured so many cases & you say I have cured so many cases but when we go publish it, no one is ready to publish it.

NO one believes it !!

And they call it as a Placebo therapy that is what is happening in Britain.

There is a great pressure in Britain that Homeopathy should be removed from National Health scheme in Britain because than somebody has proved that it is placebo.

Shown on the TV channel

There is a Panel

1 for Homeopathy & one against Homeopathy

The person who was against Homeopathy got a 2drahm bottle of Nux Vom 10M and he asked that Homeopathic Doctor that you call 10M as a very high potency, strong potency than what he did,

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he gulped that whole bottle of 10M Nux Vom & than see nothing has happened with strongest medicine that is what you do if nothing is happened with strongest medicine, that means your Pathy is what, it’s a placebo.

You say 1 DOSE, than a strong dose 1 dose

Repetition is so harmful

Drinking whole bottle on TV show of Nux Vom 10M & saying nothing happens to me, how you counter this now.

Than we call it is our very strong medicine 10M, 50M & that is how it been projected now than they say it is placebo.

The drug which cannot influence symptoms on me, how it cures??!!??

But then we require a scientific reasoning to counter it & that we don’t have with us.

We don’t know what happens when we take a drug.

We still don’t know how our drug acts till than we cannot counter.

Now there is a magician.

He is called as James Randy7 | P a g e

If you might have heard it

He has put an open Challenge of 1 million pounds.

He is a magician not a Physician

He is a Magician Challenging Homeopathy putting a Price- Anyone can win it!!!

1 million pound

A person who can proof how Homeopathy acts, how it functions scientifically???

Who will justify its action???

Who will proof scientifically that it is not a placebo???

It’s an open challenge given!!Those who want to accept it, can accept it.

Till date no one has accepted His Challenge.

Till now no one has proved it.

So no one has won those 1 million pounds till now.

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Till now no one has been able to show how exactly your drugs act.

So do you feel this is not required tomorrow.

See when you are practicing tomorrow patient will ask, how your medicine act ?

Than we give vague answers that it is DYNAMIC, it is Spiritual.

People are not ready to accept this now-a-days

I can show you 100’s of theories how medicines act, right

Ultimately scientific community wants EVERYTHING black & white

Can you show Vital force!!??

What we are referring to is an article by IIT Mumbai—

that higher dilutions retain the original substance

Research in Health Science specifically it is the activity to design

RESEARCH IN HEALTH SCIENCES

MEDICAL RESEARCH:

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Activity designed to test a given hypothesis, draw conclusions, develop or contribute to generalized increase in knowledge about health, disease, causation, remedy management.

Ultimate aim of the medical research should be welfare of the patient & development for science

MOTIVATION:

What makes people to undertake research?

To generate new knowledge, improve scientific understanding which is grossly lacking in us

Improve medical treatment new methods—

Develop evidence based medicine

Face challenges & unsolved problems.

Find hidden truth, which is not yet discovered

INQUISITIVEESS is mother of all researches

Now we have Higher purposes & Practical purposes

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Which we really believe as Homeopaths

We as Homeopaths believe whatever Hahnemann as done is the last thing & there is no scope of improvement further

Unless we come out of that attitude we will not improve

If you have accepted everything as it is you cannot do research there should be inquisitiveness.

OTHER OBJECTIVES

Compulsory work in college, internship.

Mandatory circular work in M.P, PhD

To do publications which will benefit to get higher academic post

Name & status symbol

We do compulsory research- So imagine the quality of research.

Many a times we copy & complete the journal from seniors

We do Mandatory work

My Guide wants 250 pages of thesis

- So heading changes, matter remains the same

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Guide hardly takes pain to read a Single page also

This is not only in Homeopathy, this happens everywhere

Half of the Government funding goes in repetitive research work

Somebody doing a particular work

E.g.: Synthesis of Nano-particles using : plants is a Research

Somebody doing using gold

So same idea

Somebody doing with silver

Somebody doing with copper

Idea is same, everyone will say I have published 1 paper & everyone gets recognition doing something new

Same thing is done by everyone

Other purpose of research is to do publications

If you want to be head of the department you want to have Publications because the Committee will ask you how many research papers have you published it?

In University format you have to write:

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How many International papers you have submitted?

Also how many National papers have submit?

Presentation & Research work is again compulsory for getting academic post

Lastly Name & Fame I have published so many papers- I am Scientific

Causal Links in the Research- Teaching- Practice- Triangle.

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What should be the purpose of Research?

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Research should be practice oriented than

only it has some meaning.

Research should be practice oriented than

only it has some meaning.

Theoretical research with has no utility in practice, it doesn’t help anyone & whatever you learn from practice should be put into research.

So it is 2 way

Also most important whatever you do in practice should be taught

So most of the times what is taught are not practiced.

So the one freshly passed out doesn’t know how to practice because he is give high understanding of morals, Values & what is classical & what is ideal, when he comes to the practice, he finds totally new world because whatever is taught is never practiced.

Practice is something shown as different.

So there has to be a perfect Understanding whatever you teach should be seen in practice.

And your practice has to lead to research and that research should help both things teaching also as well as practice.

When all these things will come together you will have a good research and a good practice & a scientific development

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Whenever we look at Research, we look at this person

LOUIS PASTURE:

He is one the scientist who is praised by Hahnemann himself.

Research laboratories are sacred domains, temples of future, wealth, and well-being.

Science should be way of life

Now we may have research whether Homeopathy is vaccination or not but if we read Organon Louis Pasture was praised for his vaccine for small pox & Hahnemann has written he has done a greatest thing for a mankind.

So does not mean that Hahnemann was against Vaccination.

So why we say that Vaccination is Non-Homeopathy –read in Organon Hahnemann has praised so much this person for Vaccination.

So we have lost many opportunities in the history if you go- The 1 st person even before development of microscope to think of Viruses & bacteria was Hahnemann.

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He predicted Vibrio as a Virus may be- it is not virus but he thought it is a Virus that is causing epidemics of Diarrhea- that is cholera.

So the world did not know the cause of Cholera & Hahnemann knew the cause of Cholera as a Micro-organism.

So who should be the frontiers in the Pathology & the Microbiology?

Should be the Homeopaths & today we are thinking we don’t need to study & then we are criticizing that is not the cause of disease & than we say it is the material cause of the disease & if that is not the cause of disease than why Hahnemann thought of Vibrio’s as the cause. He never said only Dynamic Influence.

He specifically said vibrio is the cause of Cholera in spite of not having a microscope.

So Hahnemann was “Open” we are not today & we say cause is what Miasm, Cause is susceptibility but not Vibrio’s.

But can you have Cholera without Vibrio

Can you have Typhoid without Salmonella??

Can you have Tuberculosis without bacteria?

Then why not ACCEPT it

We don’t want to but it doesn’t fit into our Organon definition than we can say is the exciting cause of the disease

Date: 19th January 1417 | P a g e

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 pm

Part 2

Your susceptibility & Miasms can be fundamental causes.

Organisms are Exciting cause

Even 200 years back the motive of research was to generate wealth even the person like Louis Pasture

Unless you have this motive people will not fund you

Unless your research generates the fund people will not fund you

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Types of Research:

Laboratory Research

Clinical Research

Theoretical Research

Quantitative Research

Qualitative Research

Library Research: means you have to go through literature

Whatever is published & you are deriving your research out of it without, actually work yourself- You are doing through references.

All these types have their places.

No research is inferior.

Laboratory Research— Always better because you are showing the world in front of you.

Clinical research: We all should work on it.

Fundamental research is always important.

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LOGIC IN ORGANON CONFusion

Inductive Logic Deductive Logic

This is the basis not only for Homeopathy but for Modern medicine also. They use the same Terminology.

So the basic research is : Investigation of basic Principles.

e.g.: Law of Similars.

Theory of Potentization is the basic Principle.

Basic research will have its application through the Pathy.

So what you doing are observing the events.

Drawing the Conclusions out of it.

Making a Theory out of it.

So from Natural examples which Hahnemann saw he came on LAW OF SIMILARS—that is INDUCTION--Inductive Logic

Once you form a law out of Principle than you apply to Practice is Deductive Logic

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So this logic is a part of Research work

So Fundamental research always leads to Development of new theories that is why it is important.

This is what we were taught

Basic Research

Particular ----- General

Person ----- repeated

(Clinical Trials)

Observations ----- phenomenon ----- data collection -----analysis ----- conclusion

Induction logic

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Applied research

Deductive logic

Solving problems employing well known & accepted theories & Principles.

Study specific Cases

Birth of Homeopathy, itself is a research Activity. It is not that nothing has happened in Homeopathy.

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Research in Homeopathy

Discovery of Homeopathy is a product of research

Observation in nature—hypothesis—Law of Similia

Drug proving—material medica

Clinical difficulties in chronic cases—theory of chronic miasms

Hahnemann is not the one to think of Law of Similars

There were many before him to think of Law of Similars

There are references from Ayurveda as well on Law of Similars

But the person who utilized the most Law of Similars—is Hahnemann.

So when he started with his experiments of various drugs & then he came to Law of Similars, itself was a same thing he did.

Another research activity in Homeopathy is Drug Proving our material medica would have not existed, so it’s a drug proving

When he went into practice, he had difficulty in treating Chronic diseases with their relapses that demanded a development of new theory so came “Theory of Chronic diseases”—Inductive Logic

When we apply this in treating is a Deductive Logic.23 | P a g e

Further research is needed in following subjects

New, scientific drug proving’s

Re-evaluation, reproving of old medicines.

Potency proving’s

Explanation of basic laws in light of modern science

Concept of miasm

Concept of dynamic effect

We have drug proving’s but we don’t have scientific drug proving’s what is according to Protocols

Every year there are 2 drugs proved but hardly the protocol is followed

Time has changed, needs have changed, stress increased

Potency proving’s—

China was proved in tincture form.

Lycopodium was proved in tincture form & we are

using potentised form.

So is tincture proving same as Potency, than why to potency?24 | P a g e

These are the questions to be asked ourselves.

We have explain our basic laws with respect of the modern science that is the need of hour.

This is why Homeopathy is criticized—as it is unanswered

What is Miasm—Again a Mystery

If you ask of Organon person Origin of Miasm & Necessity of Miasm:

10 people will ask differently!!!

All will answer differently!!!!

Some will say 1 miasm, some will say 3 miasms, and some will say 4 miasms and some will 10 miasms.

So what is Miasm then???

Miasm population is also over growing by the time, is there end to it.

As we don’t know what is Miasm. We don’t want to name anyone but that is the Fact.

Why this is happening & why there is a need of new Miasm than because somewhere we are lacking in our result.

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Why Hahnemann thought of Miasm?

Because he was lacking somewhere in results.

So miasm was thought to be obstacle.

So after 200 years we are now thinking of 10 miasms till we are lacking somewhere in results or we have to categorize drugs in particular miasm so that it becomes easier for prescription—that is also the intention of miasm.

Miasm was thought to be obstacle for Prescription.

But that was not the intention of Hahnemann when he thought of miasm.

So what is dynamic?

We don’t know what is Dynamic—what is meant by dynamic

And that’s why we cannot prove anything.

How drug acts— Dynamic.

How cure takes place— Dynamic.

The thing which we cannot see— we cannot explain that is dynamic.

That’s why there is Criticism.

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We don’t know what is the mode of action of our Homeopathic drugs because we don’t know what we are giving as a drug & how it acts exactly.

Lots is needed to be done on Drug Standardization—

We don’t have Drug-Standardization.

Mode of action of Homeopathic drugs.

Drug Standardization.

Stability & expiry date.

What is potency & potentization/dilutions.

Actions & role of nosodes.

We don’t know what nosodes are???

How they act???

To combat all the above situations the following evolved:

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Need for Post-Graduation study in Homeopathy

1989- Post-Graduation Curriculum.

Awareness, scope, knowledge improvement.

Upgrade skills, Organon, Repertory, Clinical subjects to follow.

PhD

Fellowship Courses

There was even great opposition even for PG Homeopathy.

What is the need for it??

What new you are learning??

The Law remains the same, drug remains the same.

The purpose was to discover something new.

To create awareness, hope & knowledge improvements.

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Basic desire to do something new.

Everybody of us wants to improve the science in new way.

Purpose remains same with certificate course, Fellowship course— that the science should improve, doing something new about it.

To develop better Understanding, Perception.

What is the purpose of the Guide?

The role of the guide is not to tell the student what to do, but guide should understand what student wants to do.

Why he has joined the course, what is his motive, what he wants to work on?

So if you get opportunity to work in the field that you like— you will do better.

Subject of interest has to be identified by you (us).

Identify 1 of the subject you want to work on

e.g.: -Pediatrics

-Posology

-Orthopedics

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-Neurology

Aim is to treat better than any other Pathy.

Date: 19th January 14

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Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 pm

Part 3

What should a Guide Identify??

1. What is the research topic??

2. Research work the student wants to do??

3. How he wants to do??

4. What is his Motive of profit??

5. And then accordingly formulate what is methodology??

6. What material he should go into??

7. We are doing the same thing in PG – in Organon, Materia Medica

And the same subjects in Under-Graduation as well, the reference books, textbooks-everything remains the same. Than what new are we doing?

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When you work on it you will get that patient only because your results will be better in those cases.

So one must pick up something related to Clinical subject.

Why do we have courses like PG, Certificate Course, and Fellowship to learn different topics in depth?

So one should identify in the practice which subject he likes & one should start working on it.

Identify your interests because your result will be better in that particular are. So your research works will help/enhance your practice.

This is the responsibility of the guide. How to go about it once you select the topic Ultimate Aim is Publication & Presentation at the end of curriculum.

Research --- Practice.

So those who feel research is not required for Practice they are wrong

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Six Arcs of Research- Teaching- Practice Triangle

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In the PG (Homeopathy), Certificate, Fellowship we have same like Educational methods in PG. program.

Theoretical/Clinical work

Ward/Hospital training

Case presentation

Poster Presentation

Group Discussion

Seminar

Article Writing

In practice we cure many cases, but when we see admitted patients, we can take more complicated cases, & learning chances grow more.

We lack in Clinical training as a bedside/admitted Physician i.e. Hospital training all over cured.

Somehow Clinical & Hospital cases in Homeopathy needs lot of improvement.

Also we even need improvement in legal system to support that.

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There are certain laws which go against Hospital practice if you want to do it into Homeopathy- whether you can give fluids, or you cannot give fluids & what types of fluids.

IV fluids, you can give- again it is Controversial—Because anything give parentally is not Homeopathy so we need to change the definition or we have to accommodate so many other things in our scope which were not there earlier—that is the need of the hour. Suppose the patient is dehydrated, Collapse & Sinking— Yes’ he requires fluid we accept that then that should be accommodated in our Curriculum.

Group Discussion is the most important thing which we avoid, is the way you interact, criticize each other fight, that is how you share your views, exchange your views but that’s limited subject on that is why you improve your understanding—

Let see what other person has to give—see no Homeopaths come to a same drugs many a times—we don’t have to understand what remedy but the thinking behind it why he has given this how he has given this that all we have to understand because we are interested in writing the name e.g.: what do you give in osteo-arthritis that is a useless question because you are not going to prescribe the same drug—so no need to write—So that is why we have seminars & open discussions.

Again these are the subjects which we don’t like.

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When MD was introduced maximum students used to fail in this medical Biostatistics subject because we don’t like statistics.

Statistics/Biostatistics:

Collection, analysis, interpretation & presentation of collected data

Tabulation

Charts & diagrams

Bars

Pie charts

Line diagrams

Software systems: SAS, SPSS, MEDICALC

As it is most of the students who come to medicine do not like Mathematics on top of it Statistics is still boring but that is important to understand a particular event.

How to project your science is also important for the people to understand & appreciate.

There are so many software’s which are available to do data analysis which you actually don’t have to do it.

How research starts??36 | P a g e

Twinkle Twinkle little star how I wonder what you are—research starts right from nursery- Age of 2 & 3

So Research starts when you ask Questions to yourself & others around you.

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This is wrong any one can do research because I am practicing I cannot do research that is wrong.

So start asking, don’t accept anything because it is said by someone.

There is something called as Null hypothesis in a research- Means you propose a theory & you counter it & call it null theory.

Suppose I say this drug cures this-

The Null hypothesis says this drug doesn’t cures this & when you try to it prove it that it doesn’t cures it, you will end up landing saying it cures it.

So start in a negative way- Homeopathy doesn’t acts- Null Hypothesis.

Homeopathy is only Placebo so start with this than you will end up proving it really acts so countering that is Null hypothesis that is also one of the research you disprove the thing & with the logical thing you come to conclusion, Yes it works.

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So your research starts when you ask questions very important

Research starts when you start asking questions.

How? What? Why? Why not?

If you accept without asking questions you cannot do research (let it be said by anyone) Let it be said by Hahnemann that is research

Inquisitiveness is mother of all research

Good research involves, a lot of hard work & little luck

Failure is not fatal, success is not final, what counts are that one continues to work & perform.

This is Research Methodology

Luck is needed

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Person who invented Benjing ring, he was fighting to identify the structure of Benjing for so many years & than he got a dream of Sarpanch having got catching a tail by mouth & than forming a ring then he got an idea that Benjing might be round like a ring structure. Now in whole amount of research he never thought of this but it was the dream which gave him this idea so that is Luck.

Penicillin is a fungus that prevented a bacterial growth- so incidental finding- but that created world that created world generation of Antibiotics so the person who observed it was a lucky one.

So luck is required to that extreme but luck is not substitute to hard work that is required.

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Good research is a team work

We Homeopathy don’t share our ideas, our combinations our research work. That is why we don’t grow.

Unless you are put depth together you can’t be a team work

Now-a-days no one can do isolated work because the technology is so advanced, the instrumentation is so advanced even the physicists cannot handle all the techniques the person who is doing NAMAAS cannot do ACM cannot do DLS. We require a team of physicists, scientists, botanists’ chemists all together.

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So this is our state

Those who want to do something

Now there is a list of things shown where you want to go

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Stages of Research1. Selection of topic :

a. Significance

b. Suitable topic

c. Own interest- not because the guide has given

2. Defining the problem :

a. State the problem

b. Specify

c. List of assumptions

3. Literature Survey :

a. Journals

b. Articles

c. Books

d. Conferences

e. Workshops

f. Internet43 | P a g e

Electronic search for references:

Medline: national library of medicine (USA)

Index Medicus

Excerpta Medica: abstracting

(Very good site, you get journal all abstracts)

Biosys: Biological science.

AMED: database for alternative medicine.

Google: It has everything, why our research work is rejected because we don’t follow this methodology.

Stages of Research

4. Assessment of current status of topic : to avoid repetition.

5. Formulation of hypothesis : Scientifically reasonable predictions verification of hypothesis---- theory.

6. Research design :

Work plan approach.

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Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 pm

Part 4

Stages of Research

Actual work starts after selection- Collection of data

7. Actual investigations:

8. Data Analysis:

9. Interpretation of results:

10. Report, Presentation:

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Research top

Do I know the field?

Is it important in my field?

It is ethical?

Has anyone already worked on it?

Is my timing correct?

Do I have sources & funding?

Will my work have impact in my field?

Duke of Queen- asked him what is the use- if you have electricify induces some magnetic field but what is the use of this in practice because electricity was not known at that time when he has postulated that electricity induces magnetic field.

So clinical relevance was not there of that study

So what Farradey said this is “like a new born baby”

New born baby has no purpose

It is the time which will decide what this baby

will do.

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And now all the appliances, & electric foils & magnetic inductions, & all the techniques that we are seeing today it is because of that Farradey experiment.

So he was before time but he didn’t get the credit of the experiment.

So time is also important to get the credit.

Conclusion: We should keep working. This is the baby that we

have time will see what is its utility.

F.I.C.E.R Criteria’s

For good research

F----- Feasible (time, money, expertise)

I----- Interesting

N----- Novel

E----- Ethical

R----- Relevant48 | P a g e

Good research is scientific, systematic, logical & replicable- this is relevance to Homeopathy. We have lot of results but they are not replicable. If I prescribe something in this condition & symptomatology, it acts but if you prescribe if it is not working than it is not a replicable result. The criticism for Homeopathy is you talk a lot but you don’t show reproducible effects, consistent effects.

So reproducibility has to be there.

Up to World War there was nothing like Ethical research.

This Concept of Ethical research came because of German people- they did in human research activities on the prisoners. So there were no Guidelines earlier.

Now we have Americans & Indian Guidelines.

Medical Research & Ethics:

Ethics = moral principles.

Prior to 1947 no ethical guidelines existed.

1897- American medical association- code of medical ethics.

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1947- Nuremberg Code formulated, after shocking experiments on prisoners of World War II.

Voluntary participation, informed consent—Most important—It should not be forceful it should be written consent.

In drug proving also we have to take written consent.

Helsinki declaration 1964

National research act 1974

UNESCO documents 1977

Indian council of Medical research 2000

Basic principles:

o Respect the person

o Beneficence

o Justice

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Ethical Research in Homeopathy

Homeopathic practitioners regulations, 1982

Clause (1) of section 33, read with section 24 of Homeopathy central council act, 1973

Oath

Duties

Misconduct

Human experiments: Randomized controlled trials

Compare Rx group with control group which does not receive treatment(Placebo).

Blinded RCT :

o Single blind method : Participation does not know what they are receiving.

o Double blind method : Participation & care providers do not know.

o Triple blink method : Participation, care provider, controller do not know who is receiving which drug as it is coded.

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Publication:

No matter how great are your results, work is incomplete & not acknowledge unless you publish it.

Charles Darwin : Scientist’s life would be happy if he had only to observe & never to write.

A good scientific paper can be rejected for publication if it is not written correctly.

As Homeopaths we are very bad at writing & publishing it.

We require in Homeopathy, good documentation.

Publication:

Articles for submission to journal have to be formatted as follows: title, introduction, methods, results, discussion. As per requirement & tradition of journal.

Details of procedure for submitting the article can be obtained in detail at http://www.icmje.org.

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Peer reviewed journal/article

Submitted article is send to experts of matching competency, who are not part of editorial staff for review.

Based on recommendations of peer reviewed helps author & editor to improve the quality of article/journal.

Asian Journal of Homeopathy IJHM.

British Journal—Peer reviewed journal.

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How to write Research Paper

1. Title of paper

2. Byline & affiliation

3. Keywords

4. Abstract

5. Introduction

6. Review of literature

7. Materials & methods

a. Experimental details

b. Theoretical basis

c. Methodology used

d. Study design

e. Sample size & statistics

8. Observations & results

9. Discussion

10. Conclusion: one paragraph (few lines)

11. Acknowledgement

12. Reference & Bibliography

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Otherwise you will not have any credibility- don’t say I have heard it somewhere

1. Title: must have key words avoid words like: “scope of ….”, “Study of …..” accurate, brief, clear

2. Byline & Affiliation (referral address not the postal address): name, degree, affiliation, corresponding author, e-mail.

3. Key words: most important words (5-6)

4. Abstract: brief, less than 150 words, aim, objective, scope, result, conclusion.

5. Introduction: reason for your work, lacunae in existing literature, should increase interest in reading.

6. Literature review: sequence of work done by others

For every journal they have their own methods of writing the references, it may vary with each journal. So standard pattern is what you 1st write the name of the author- usually it is a corresponding author.

If you have 4 authors of the article

One is called as

1. Corresponding author-- If you have any queries with that related article than you will to correspond to that author- he will solve your query- so that name comes 1st.

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Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10 .00 am – 5.00 pm

Part 5

1. The Title

2. The Book reference

3. Year of Publication

4. Volume

5. Section

6. Page no

This format is only accepted

The purpose is someone wants to cross-check the references.

56 | P a g e

Funding Agencies

Extra Mural

DEPT. of AYUSH: E.M.R. scheme, Rs3000000 Dr. Girish Gupta

M.U.H.S: Rs100000

DEPT. Of Science & Technology- Crores of Rs (DST)

INDIAN COUNC IF FOR MEDICAL RESEARCH

UNIVERSITY GRANTS COMMISSION.

No Homeopaths are ready to do Research.Only all Ayurveds & Allopaths go for research.

57 | P a g e

MISSION Generating knowledge by leading edge research & to promote

academic growth by offering Professional & industry oriental programs

To identify, based on an informed perception of Indian, regional & global needs, arrears of specialization upon which institute can concentrate

To undertake collaborate projects which offer opportunities for long term interaction with academia & industry

To develop human potential to its fullest extent so that intellectually capable & imaginatively gifted leaders can merge in a range of professions.

Pharmaceutical industrial developments as per global standards & requirements.

58 | P a g e

Homeopathic Pharmacy potentization

Mathematical mechanical process in which inert power of drug is activated by trituration

Action of homeopathic drugs is dynamic?

Inert drug becomes active

Change in properties of substance

More dilution, more strong is the potency

Years have passed our Definitions have not changed.

Potentization

What do we exactly do by Potentization.

Why it is done in this particular way only.

Dilution or Potentization? Is it same?

Why to triturate who do we give Succession.

Why 10/100 strokes, why one hour for Trituration.

How far we can do Potentization cm, mm…..

59 | P a g e

There is confusion at higher level.

We don’t have answer which is the highest potency.

Questions ????????

How and why these dilute medicines will act

What is left after 24X, after crossing Avogadro’s no?

What is acting?

Can we potentised without trituration, succession

How do we have liquid potencies of insoluble substances, metals like lead, gold, copper?

My query to my teacher is how you prepare Plumbum Met liquid potency

Lead is not soluble

Highest metal

How you produce liquid potency of insoluble drugs like

Plumbum Met

Aurum Met

Cuprum Met

All are metals, insoluble, how you prepare liquid potencies???

60 | P a g e

More questions

Why diluted Nat-Mur produces s/s, but Nace is daily diet does not same with coffee than coffee should not act but it acts.

Sand is inert, why Silicea gives s/s

Many drugs proved in tinctures, but also used in higher potencies (China, Lyco, Chelid, ledum)

Difference between tincture & potency

Then why we give restriction-

No coffee, garlic, onions

CARDUS MAR. TINCTURE

MOST OF THE PARTICLES

LESS THAN 10

MICRONS

61 | P a g e

Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 pm

Part 6

-TINCTURES COULD BE USED AS INHALERS- THIS OPENS A NEW FIELD FOR US

OUR TINCTURES ARE PREPARED LESS THAN 10 MICRONS.

-WHY NOT PREPARE HOMEOPATHIC INHALERS. WE CAN INHALE HOMEOPATHIC DRUGS

-HAHNEMANN HAS SAID THAT YOU CAN PREPARE HOMEOPATHIC INHALERS. IT IS WITHIN THE PERMISSIBLE LIMITS. IT IS LESS THAN 10 MICRONS.

62 | P a g e

-THERE IS A METHOD WHERE WE CAN USE HOMEOPATHIC MEDICINES BY OLFACTION THAN WHY NOT GIVE HOMEOPATHY AS INHALERS WHY NOT HOMEOPATHIC DRUGS USED AS NEBULIZERS. THAT TIME THESE TECHNIQUES WERE NOT AVAILABLE NOW WE HAVE.

MOST OF THE DRUGS ARE LESS IS LESS THAN 10 MICRONS

Than another tincture was taken, this was given to IIT Mumbai for working this was Terminally Arjuna tincture. And there were very skeptical & said if you have to tincture have bigger particle size that will spoil our instrument so what they did is they filtered it to 2 microns filter & subject it for Dynamic light scattering for DLS & what it shows the Terminal Arjuna tincture it’s a plant extract contains particle of 2-3 nanometers is equal to 22000 microns.

63 | P a g e

Permissible limit is 10 microns so we have so small 10 microns means 10X1000 nanometers -10000

Nanometers particles size we are allowed for inhalation & we have 23 nanometers size.

Right now we don’t have any standard in manufacturing what should be the particle size of the drug.

Particle size of Arjuna terminal tincture was 7.2 nanometers.

RBC is 70 microns.

70 microns -70000 nanometers

RBC size is 1000 times more than our particle size of our tincture

Let potentize and see what happens to the particle size so at least we will know what we are doing by potency.

Role of Succession

T Arjuna 2XPotency = DLS study

PARTICLE SIZE = 3.9NM

IX- I prepared particle size became 5.8 from 7.2, when I went to 2X it became 3.9

64 | P a g e

Holarrhena 1X 2675nm

65 | P a g e

When I went to 3X it became 1 nanometer (NM). This was the particle size at 3XPotency = 1NM

So question now is what will happen at 4X. The answer is I don’t know because whatever instruments are available today we can measure only up to 1NM; below one nanometer we don’t have any instruments available up till now so we cannot measure below one nanometer.

But what are we doing with succession is shown.

66 | P a g e

Why to SUCCUSS:

Is progressive reduction in particle size if we go in Sequence?

difference between could not achieve with dilution & succession is required

So now 1 experiment cannot prove everything

They say it happened only once- So not a Big deal or a great achievement.

This was done in the University of Mumbai Kalina University.

So they were helpful enough to allow me to do this because I can’t handle these instruments.

MALWEN AMIL is a No. 1 famous British Company World Wide; they supply instruments to all premium institutes like IIT, DIFR.

These Institutes don’t allow us to use these instruments. They have no gain in Homeopathy. So we could not get appointment with them.

Special case was considered & called to Baroda to utilize instruments with charges ofcourse.

67 | P a g e

Holarrhena IX 267nm 2.6 microns

Let see what happens at 2X1000nm

Less than ½ sizes

Now same result with Bombay instrument experiment & this Baroda Instrument experiment.

Now we have same result 2 experiments consistently we are reducing particle size by Succession.

I am biggest skeptic.

HOMEOPATHIC TINCTURE

PART OF THE PLANT/WHOLE PLANT

TANNINS, SAPONINS, FLAVENOIDS

CELLULOSE STARCH

MUCILAGE

Ca, Mg, Zn, Cu.

Soluble and insoluble

Colloidal solution

Scientists are Skeptic of all

68 | P a g e

They asked me a Question you are reducing size of what because you take a plant extract, plant extract doesn’t mean only Alkaloid, you will have cell, cellular protein, cellular debris, Dura-matrix, trace element will have together in tincture, and you are reducing size of what.

No answer

Then approached to Indo German Company.

Dr. Rabram Patani Owner is a Pharmacist, educated in Germany.

Recently Awarded for His Manufacturing Unit.

COLCHICIN ALKALOID (POWDER) INDO GERMAN

ALKALOIDS

69 | P a g e

Sir approached him- I said I want your product for Homeopathic drug experiments- So he was very curious!

Why he wants?

Because no one sells Alkaloids- Because people are very skeptical to give alkaloids directly.

So wrote an application for the purpose of requirement & gave original alkaloid & was very helpful.

Gout Nil is- Colchicine & we have a drug colchicum, but we have whole extract of it- Alkaloid in it is a Colchicine.

s

70 | P a g e

Role of Succession

T Arjuna 2XPotency = DLS study

PARTICLE SIZE = 3.9NM

IX- I prepared particle size became 5.8 from 7.2, when I went to 2X it became 3.9

In order to avoid confusion of particle size

I prepared at home from alkaloid- Colchicine tincture not Colchicum tincture- particle size reduced even from alkaloid not only whole plant. Consistently same results

Now we have proved it 3RD TIME:

1. Bombay institute

2. Baroda institute

3.Now at Home

Now all the Nano-particles have disappeared because we have gone beyond 1 nanometer D.L.S cannot accept anything below 1 nanometer.

Now we are getting Alcohol & water mixture patterns.

All the particles have gone beyond that level we are not measuring it.

71 | P a g e

CONCLUSION: We are reducing particle size by Potentization

Trituration and succession lead to progressive reduction in size of drug particle.

Trituration and succession is much more than just dilution.

Particle size of tincture & lower potencies is in the range of few microns nanometers.

Nano size particles will form colloidal solution & will not settle down- property of Nano-particle.

SOLUTION, COLLOID, SUSPENSION

SOLUTION: MIXTURE WITH PARTICLE SIZE AT MOLECULAR OR IONIC LEVEL 0.1 TO 2MM, HOMOGENEOUS

COLLOID: MIXTURE WITH PARTICLE SIZE 2 TO 1000NM, HOMOGENOUS.

SUSPENSION: HOMOGENOUS MIXTURE WITH PARTICLE SIZE GREATER THAN 10000NM.

72 | P a g e

Our Standard Criteria should be:

When we prepare tincture it should be colloid or solution not Suspension- But until now so such criteria’s are introduced. So we have to introduce.

Ex: Calendula Mother tincture, if you keep it for some time it settles down.

Why it happens?

1. One is practice size.

2. Every solution has a capacity to accommodate soluble & insoluble compounds.

3. When you change or exceed that capacity either solute is more & solvent is more the soluble compounds will become cob web.

If you add alcohol to that solution cob web will disappear.

73 | P a g e

Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 pm

Part 7

Calendula is a fresh plant.

It is drug strength ½.

Tincture when prepared alcohol concentration is only 96% or less than 46% water is more. So substances which are not soluble in water will form cobwebs

So rather than calculating or preparing tincture, depending on moisture content, we should prepare depending on the stability of the product. So will have to design a new way of producing new way of preparing tincture rather than depending on moisture contents.

74 | P a g e

NANO PARTICLES

K.ERIC DREXLER, 1980

NANO TECHNOLOGY

NANO MACHINES

NANO ROBOTS

1NM = 0.0000000001MT

1 MICRON = 0.0000001MT, 1 MICRON = 1000NM

1NM = 10HYDROGEN ATOMS IN LINE. So we reach this level at 3Xpotency.

75 | P a g e

RELATIVE SIZES

RBC SIZE = 6.8 MICRONS, 6000-8000NM

WBC SIZE = 7.21 MICRONS, 7000-21000NM

CELL WALL = 10NM, CELL MEMBRANCE 7-10NM

HAIR = 70 MICRONS, AEROSOLS= 7-10 MICRONS

We have better penetrability of the drug because of the size. It can even penetrate the viral wall, the cell wall forget about the human being.

So many of the Antibiotics size is larger than that, they don’t penetrate.

That is why Research has to be in time. At Hahnemann’s time, this material was not available. This technology & details & physical details were not available- so he was not able to make understood that how all this is happening.

Now we have all this material available so now we can explain our processes better so time is right to explain it now.

76 | P a g e

NANO PARTICLES

Reduction in size brings about changes in the properties.

Size determines the properties.

Change in Physical, electrical, optional properties.

Increase in surface area to Volume Ratio.

Show faster Reaction, Diffusion Or Ionic Transport (Nano Ionics).

If you change particle size properties will change.

Macro to Nano, Change in Properties.

Absorption of Solar radiation is better.

Smaller the particles better the Absorption.

Opaque Substance becomes transparent- Copper.

Stable material becomes combustible- Aluminum- harmless metal

We could never dream of it.

Gold becomes- RED- Black.

Gold Silica- Red.

Gold melts at lower temperature- 300C.

Insoluble gets soluble- Gold- Platinum met, Aur. Met, cup. Met potencies.

Insert Gold- Potent Chemical Catalyst.

77 | P a g e

Nano Particles form stable suspensions/ Colloids.

Colloidal solution (solid + liquid).

Overcome the Destiny (Otherwise will Sink).

No Expiry Date??

Colloidal Gold

Gold has no expiry date.

78 | P a g e

Change in Colour of Gold

Change in color of Gold

79 | P a g e

Size Determines Properties

Uniform, transparent and no sediments.

80 | P a g e

POTENTIZATION

Insoluble substance Metals- Pb, Cu, Au.

CoLLoidal Copper.

81 | P a g e

Trituration- Grinding- Progressive reduction in size of Particles- 6X

Less than 100nm size approx. can be converted now to Colloidal liquid form. And further Potencies can be Liquids.

82 | P a g e

Silica 6X- Nano Silica- No more Insert

Natrum Mur- Change in Properties- Acts Differently

83 | P a g e

So you can prescribe Coffea Cruda to Coffee drinker Natrum Mur as well as we eat salt everyday.

ROLE OF SUCCESSION

Potentization is not Dilution

There is Progressive Reduction on in size of Particles? With succession

Less the SIZE = More the Stability of Colloidal Solution

Longer shelf life

?? no Expiry Date

Achievements

Nano particles in Tincture & Lower Potencies Confirmed

Role of trituration

Liquid Potency after 6X

Change in Properties of Crude & Potentised

Drug

84 | P a g e

EFFECT OF SUCCESSION ON SIZE OF PARTICLES IN SUCCESSIVE POTENCIES

NANO-PARTICLES ARE IN EVERY DRUG

H.P.I. STANDARD

1 LITER OF TINCTURE 100 GMS OF SOLIDS

1 ML (12 DROPS) 0.1 GMS

1 DROP 0.0083 GMS

HOMEOPATHIC DOSE USED FOR TRIAL

10 DROPS- 0.083 GMS

Quantification METRIC Conversions Org.

85 | P a g e

CALCULATION OF NO. OF NANO PARTICLES PER 10 DROPS OF TINCTURE: NANO PARTICLE SIZE 7.2 NM

VOLUME = 4/3X3.14X7.2X7.2X7.2= 1562.66NM

3 = 0.156266X10. ^8 LITERS

VOLUME OF 10GM OF NANO PARTICLES = 14.49 CM3

= 0.01449 LITERS

NO. OF PARTICLES IN 10% SOLUTION HAVING 10GM NPS

= 0.01449/0.156266X1/10. ^8

=9272650.48NP IN 100 ML

VOLUME OF 10 DROPS = 0.35ML

100ML CONTAINS 9272750NPS

0.35ML CONTAINS 32454NPS

10 DROPS OF TERMINALIA ARJUNA TINCTURE CONTAINS 32454NPS COUNTABLE PARTICLES,

AS THERE ARE UNCOUNTABLE PARTICLES AS WELL.

Unanswered Questions

WHAT HAPPENS AFTER SIZE OD 1NM.86 | P a g e

WHAT HAPPENS AFTER POTENCY OF 24X.

HOW MEDICINAL PROPERTIES ARE RETAINED.

IS POTENTIZATION ENDLESS.

WHAT IS DYNAMIC POWER OF DYNAMIC ACTION.

What is dynamic?

-Spirit

Force

-Energy

-Could not be seen

That is what the definition:

Hahnemann also gave examples what is Dynamic

Gravity of Moon & Earth, Moon & Sun

Now Scientists are working on what particles are responsible for gravitational energy—Graviton.

Mass & energy & interconvertible.

Date: 19th January 14

87 | P a g e

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 pm

Part 8

It is said by Hahnemann Measles transmission is Dynamic Measles & Chicken pox is a transmission of virus = 20nm.

So what was dynamic to Hahnemann may not be Dynamic to me now.

Magnet & Iron Relationship.

Every remedy can produce all type of symptoms what is Deep acting & superficial Actions.

Indicated remedy is indicated remedy.

Definitive idea is symptoms rest all are our assumptions.

It is if give Constitutional medicine- than there won’t happen any changes!?!??

Why to make things Complicated??

Why do we make theoretical assumptions??88 | P a g e

Let us keep everything simple

Question is a good sign that you may do research

A Case: of Infarct with triple vessel disease

Terminalia Arjuna- Patient was much better

DOSE: 1-2 gms/day

<50 MIRCRON SIZE

ALLOCHOLIC EXTRACT

Arjunarista

300gms Arjunsal/1000 ml

Counter Product/Homeopathic Tincture

Drug strength 1/10

100 Gms Solids/1000 ml

TRITURATION, MACERATION, PERCOLATION

Crude Drug- Bark

89 | P a g e

Powdered- 10.50 microns

Maceration, PERcolation

Filtration

Tincture : 50-60 nm

10-100 nm

TERMINATION TINCTURE

100 gms SOLIDS/LIT (H.P.I. STD)

100 DROPS OF TINCTURE- 0.003 gms

AV Particle size 23 nm

D.L.S- Study was shown graphically

METHODOLOGY

BAKSON DRUGS INDIA 450 ml

90 | P a g e

Manufacturing Date: Aug.2008

Lot- 688

32 Patients: Lipid Profile, Work, Diet P/H, F/H, Habits, Stress Associated S/S

No other Antilipid Drug

Patients selected randomly

CLINICAL TRIAL

Short term- Less than 2 months

Longer term- more than 2 months

Dose- 10 drops with water at night

CASE NO. 4 MRS.S HIRLEKAR, F/70

130/80, HOUSE WIFE DM, OA KNEE JOINT, ADHESIVE CAPSULITIS SHOULDER HYPOTHYROID, CERVICAL & LUMBAR SPONDYLOSIS91 | P a g e

NON-VEG, DESPAIR

2/11/2009 4/12/2009

CHOL 244 228 6.50%

LDL 167 146 12.50%

VLDL 36 33 8.30%

TG 180 165 8.30%

HDL 40 48 20%

Which is Cardio protective

In Allopathic Literature there is hardly any drug to increase HDL

Literature only says Exercise, Veg Diet & Alcohol in small quantity.

Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology92 | P a g e

Time: 10.00 am – 5.00 pm

Part 9

No Indian Journal accepted this for Publication- because they said this is not Homeopathy- where is law of Similars here??

You are giving tincture not homeopathic base.

This was finally published.

By Scientific American Publishers readily

Case No. 1 MR. S.B PALEKAR, M/57

DESK JOB H.T ALLERGIC COLD AND COUGH, ACIDITY, GASES, CERVICAL SPONDYLOSIS SLEEPLESSNESS, NON-VEG, 170/100

93 | P a g e

11/09/2009 6/12/2009

CHOL 268 197 27%

LDL 192 123 35%

VLDL 32 20 45%

TG 186 100 46%

HDL 38 52 36 %

No one can does it, no Pathy can do this

It’s a good Anti-lipid drug

More than 2 months

94 | P a g e

PATIENT NUMBER

CHOL REDUCTION %

HDL INCREASE %

LDL REDUCTION %

VLDL REDUCTION %

TG REDUCTION %

1 27 36 35 45 46

5 25.8 -- 41.8 19 18.9

8 37 50 30 - 23.2

11 42 21 37 - 5.2

13 23 5 26.1 24.2 23.9

20 28 7.1 39 10 31.5

25 15.6 14.2 25.2 50 46.9

27 13.8 33.3 24.8 41.6 41.6

29 25.4 21 46.2 33.3 12.2

30 17.7 4.6 11.1 42.3 48.7

-

95 | P a g e

AVERAGECHDL

REDUCTION %

HDL INCREASE %

LDL REDUCTION %

VLDL REDUCTION %

TG REDUCTION %

MEAN (GRI+GRII)

16.7 8.1 20.7 16.2 19.3

MEAN (GR.1)

12.54 1.86 15.7 9.4 14.27

MEAN (GR.2)

25.53 21.3 31.6 33.1 29.8

TERMINALIA HUMAN TRIAL

Dose: 0.083 gms

Size of Tincture Particle: 23 nm

Increase in H.D.L

Optimum period: 8 WKS or more96 | P a g e

Oral Route

Our size of the tincture is much less than Ayurvedic System.

Applications of Nanomaterial

SILIBININ, SILYMARIN

140 MG SILYMARIN TABLET CARDUS MAR

97 | P a g e

-

Is introduced to control Liver Cirrhosis, Fatty liver- only drug in Allopathy.

Allopathy people had made a huge market from our patients

83mg of whole plant extract- 1 or 2mg or less than 4mg every day to cure Jaundice,Liver Cirrhosis, etc. this what we need- Allopathic give 140mg/day.

Best Example Particle size

TROPICAL DIARRHOEA AND DYSENTERY

E COLI AND PROEUS

98 | P a g e

HOSPITAL ACQUIRED RESISTANCE STRAINS

AGLE FOLIA TINCTURE

HOLARRHENA ANTIDYSENTRICA TINCTURE

10-15 DROPS WITH WATER

METHODOLOGY

E COLI AND PROTEUS COLONIES GROWN ON AGAR PLATES

PLATES INOCULATED WITH 0.1 ML OF TINCTURE (WELL METHOD, STERILE DISC)

RESULTS COMPARED WITH CIPROFLOXICILIN (WHICH HAD SHOWN HIGHEST SENSITIVITY)

ZONE OF INHIBITION WAS COMPARED

E COLI CULTURE

AEGLE FOLIA TINCTURE

17MM ZONE OF INHIBITION99 | P a g e

ZONE OF CIPROFLOXICILIN COMPARED TO AEGLE FOLIA

HOLARRHENA TINCTURE, ECOLI

100NM SIZE PARTICLES

HOLARRHENA, ECOLI

MICRON SIZE TINCTURE NANO SIZE TINCTURE

ZONE OF INHIBITION MM ZONE OF INHIBITION MM

ALCOHOL 13 ALCOHOL 13

E.COLI 11105 22 E.COLI 11105 25

E.COLI 10536 24 E.COLI 10536 26

E.COLI M200 24 E.COLI M200 25

HOLARRHENA, ECOLI

100 | P a g e

2.6 MICRONE,

1000Nano

No ZONE, 6-7mm Zone of Inhibition

101 | P a g e

Drug Sensitivity problem could also be tackled with Allopathy.

When this was published this was mostly accepted by the Allopaths readily so only change the particle size- Antibiotic resistance.

THIS WAS PUBLISHED IN JOURNAL OF NANO- STRUCTURES

102 | P a g e

INTERNATIONAL JOURNAL OF NANOPARTICLES

2010, 3,280-296

R. RAVICHANDRAN

Producing Nano Crystals can allow the Medication to be absorbed by Govt.

Even if Drug is not soluble in water.

Nano crystals can make drug soluble in water. Even if bulk Drug is not.

Adding Small Quantity of Organic Solvent such as Ethanol, Coupling with charged ion to increase Bioavailability .

TINCTURE, NANO SUSPENSION

ENHANCED ANTIMATERIAL ACTIVITY OF LUMEFANTRINE NANO POWDER PREPARED BY WET MILLING, DYNOMILL

103 | P a g e

TECH.0.231 MICRON,

SINGHANIA UNIVERSITY, RAJASTHAN

IBUPROFEN NANOPARTICLES 270 NM

NANO SUSPENSION

INSTITUTE OF PHARMA

INNOVATIONS, BRADFORD, UK

Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

104 | P a g e

Time: 10.00 am – 5.00 am

Part 10

University of Jerusalem

Water Dispersible Powder Composed of Nano Particles of Insoluble organic compounds with Micro/Nano emulsions

Dose required is less, More Bioactive

Longer shelf life

Simvotin, Celecoxib

-Same logic Reduce Particle size

This is what we are doing, since 200 years back,

but since we could not explain all this we could not take the credit.

BOEHRINGER- INGELHEIM PHARMACEUTICALS, USA

Preparation of Nano particles of water Insoluble compounds by Wet Milling & High Pressure HOMOGENIZATION.

Nano Suspension.105 | P a g e

250-400 nm.

Danarole, Mebendazole.

NALAILAK UNIVERSITY OF THAILAND

Nano Suspensions, Sub Micron Colloidal Dispersions.

Poorly Water Soluble Compounds.

Albendazole, Omeprazole GLUCOCORTICOIDS.

Summary

Less Soluble- Less Absorption

Larger Molecule- Less Cellular Diffusion

Reduction of Size- More Bioavailability106 | P a g e

Lesser Dose Required- Less Side Effects

Similarity Between this Concept & Homeopathic Tinctures, Ayurvedic Extracts and NANO Technology

Now these 2 sciences are come close together now, same Principle Ultimately Allopathy is coming closer to our Science Principles

ALOE VERA TINCTURE

Prepared by Dr. R.S Barve

MICRON SIZE AND NANO SIZE

-

There are various methods for reducing sizes of the particles:

1. Grinding

2. Homogenization

3. Sonication

Advantage: Standardization in Preparation.

107 | P a g e

Nano medicine only supports Lower Potencies to Tincture not High Potencies.

Investigations of patients were shown before & After Terminale Arjuna given.

Acute Lumbar Disc

Surgical? / Medical?

Shifted from Goa to Mumbai for treatment.

Fainted with sudden pain after Lifting.108 | P a g e

ACUTE LUMBAR DISC WITH RADICULOPATHY.

NEXT DAY- Acute Retention of Urine.

NEUROGENIC BLADDER

Due to Massive Disc Compressing on L5, S1 N.Roots.

Neurosurgeon planned for Spinal Decompression Next Morning.

Restless & Irritable with pain while Lying Down.

Unable to Lie Down, Sits up frequently.

Shooting pain, Back--- (L) Leg up to Foot.

Pain with Numbness, Neuralgic Pain.

Unable to Lift (L) Leg with pain.

With new Development of Neurogenic Bladder and impending surgery.

Anxiety, Hopelessness, Irritability.

Kept Complaining about Staff--- Chatting and making Noise.

Jerk or Touch to the bed- Screaming.

Businessman from Goa, Mining.

Had been through difficult & Rough times.

Withstood All Odds.

Hard Working, Obstinate, irritable.109 | P a g e

No one can Question him if he is Angry.

Difficult to keep him in bed even for one day.

When the Ambulance reached the Hospital-----

----- ------.

Difficult to Argue with.

Abusive at times.

Impulsive.

Recurrent Acidity, G.I. upsets due to Stress & strains of Business.

Obstinate- Not to Listen to anyone.

Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 am

Part 11

SECTORAL TOTALITY110 | P a g e

11/3 10/5 9/5 8/4 6/4

SULPH BELL NUX V SEP LYCO

1 BACK PAIN SITTING >

4 1 1 1 1

2 BACK PAIN LYING <

4 3 3 3 3

3 BACK PAIN JAR<

3 4 1 3

4 BACK PAIN TOUCH <

1 3 1 1

5 BLABBER RETENTION PARALYSIS

1 1 1

O/E: (L) S.L.R----- O DEGREE, UNABLE TO LIFT

(L) E.H.L- - Weak

Numbness of Lateral Border of Foot (L)

P.S.M.S. ++++

Retention of Urine

M.R.I: L4-L5, L5-S1

Postero Lateral Disc Herniation111 | P a g e

List of entities to:

Acute Lumbar Disc Prolapse

Neurogenic Bladder

Weak E.H.L

S1 Sensory Loss

Motor & Sensory Deficit

Posted for Surgery

Surgery OR Complications

Acute Retention, Paralysis of Bladder

Compression of Nerve Root

Neuralgic Pain, Shooting Pain

Pain with Numbness

Fainting with Pain

Pain (Touch, Jar, Noise)

Unable to Lie, has to Sit up, CLying

Irritable with pain

-Unfortunate we lack Hospitalization set up where patient could be under observation

112 | P a g e

Sectorial totality/ only Presenting Symptoms

Businessman

Obstinate, Haughty

Hard working

Irritable, Abusive

Impulsive

Difficult to Argue

H/O Gastric & Hepato Biliary Complaints

Drug: Nux Vomica

Risky Case as he was posted for Surgery

Nux Vomica 1000

In Deviated Doses 2 Hourly. On 2/3/2001

Took Discharge against Medical Advice

Restlessness, Irritability> by evening

3/3/2001 :

P.S.M.S. ++>

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Pain+>

SLR.Q, Sensory S.Q

Slept well

Nux Vom. 1000 in Deviated Doses 2 Hourly

Now Patients relatives started Bothering

4/3/2001:

Overflow of Urine with Catheter- 1st sign of good improvement

2 hourly Bladder Training

Sensory SQ

SLR SQ

Nux Vom 1M CT

5/3/2001:

Catheter Removed

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SLR 10-15 Degree

Sensory SQ

PSMS >>

Pain>>

S.L. 2 hourly

Now at least relatives are happy as the bladder is improving.

S.L.R improving to 60 degree in 2 weeks.

Painless S.L.R & Walking in 4-5 weeks.

Sensory symptoms took 2 months to improve.

Retrospectively we can say we have treated a surgical case

Acute Disc: Medical OR Surgical?

Limitations

Scope of Homeopathy

Management: Rest, Position

Local Heat or Cold Exercises, Physiotherapy Posture

Those who have slip disc

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They should lie down completely

CASE: Recent case last week

Presentation

M/30, fever since 2 days

100F on day one, today 103F

Occipital pain fever with, throbbing

No GI upset, thirst increased+

Urine: n, Stool : n

Took p. cimol, felt better

Necessity to Examine

Pain abdomen, walking with bending double

Sitting restless, bending forward

Was sleeping on abdomen at night

O/E: Pulse: 130, temp: 103F

Pain (R) iliac fossa, guarding, rebound pain

<pressure, C extending legs

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Tongue white in center

So it is a case of Acute Appendicitis

??whether to refer for Surgery or not

WBC: 19200, N80, L12

Urine: RBC+, 4-5

Occ. Blood: +

Pus Cells: 1-2

USG: Probe tenderness (r) iliac fossa, fatty Live

Micro-hematuria confirms Appendicitis infact

Diagnosis is confirmed for Acute Appendicitis

Date: 19th January 14

Name of the Speaker: Dr. R.S. Barve

Topic : Research Methodology

Time: 10.00 am – 5.00 pm

Part 12

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These dilemma you have to solve on your own, here no one can help you.

You should instruct your patient that you have to give feedback everyday.

Inform him thought I am treating you I may refer you for surgery.

Acute totality

Pain abdo: > bending double, > sitting bend forward

Pain < extending legs, > lying on abdomen <pressure

Headache, occipital, throbbing

Thirsty fever with Tongue: white center

Acute appendicitis

Earlier patient was given Lycopodium as a Constitutional remedy 118 | P a g e

Totality is covered by Belladonna- when symptoms agree give it, do not think about acute, superficial, deep etc., etc.

Now what to give the drug which covers more number of rubrics more number of rubrics or which is 1st in the list to tackle this there is a function which is called as 1 mark—

Click it- so all this gradation disappears & every drug is only 1 mark so only drug which covers most number of rubrics with come ahead.

Than we get real picture.

Surgical opinion- Keep all the options open.

Belladonna O/1 in deviated doses.

2 hourly X one day

Liquid diet

Surgical opinion: adv. To operate appending next day

Temp: 100F

No Guarding119 | P a g e

No Rebound Pain

Pain (R) iliac Fossa on Deep Palpation

Patient decides not to go for Surgery because I am already better

Organic Pathological Case.

LM potency is low potency.

This prescription is Sectorial, local & pathological.

As Acute phase goes reduce repetition & increase the potency.

Strychnine- never give in low potency as it is poisonous- Nux Vom

0/3 is given on follow up.

This is on the contrary if patient improves I increase the potency

Case of OA:

I advise knee replacement in the patients whose range of movement is less than the artificial joint.

Artificial a replaced joint has a range of movement average 0 to 90o. Most of than cannot move more than 90o.

Practical problems are to be considered- Commode facility.

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I won’t refer patient of 90 years old for joint replacement.

Cure, Palliation, Compensation

Cure: Stage IA, IB

Palliation: Stage III

Stage II: Partial Cure Structural Changes Compensated

Classification of OA

Management: Medical or Surgical

ROM: Range of Movement

Deformity

Pain

Work type

Cost

Age

Quality of life

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Management of Osteoarthritis

Medicines

Physical Measures: Exercises, Physiotherapy, Heat, Diathermy, Cold Qceps, HAM, Exercises

Diet

Vitamins? Calcium?

Local Applications?

Education: Change in Life Style

Shoes, Wt. Loss, Posture Work

GENU VALGUS

GENU VARUS

Pattelo Femoral Changes

We can’t regenerate the Cartilage

Osteo-arthritis

Clinical:

o Pain

o Swelling

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o Restricted Movement

o Widening of Joint

o Grating, Locking

Radiological:

o Change in Alignment

o Reduction Jt. Spaces

o Osteoarthritis

o Erosions, Cysts subchondrial

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