DNMTsLungLiverKidneyHeartPlacenta Gene nameAccession number -1,88-2,001,55-1,07-1,23...
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DNMTs Lung Liver Kidney Heart Placenta Gene name Accession number -1,88 -2,00 1,55 -1,07 -1,23 Dnmt3a-ps2 AB191343 -11,33 -7,02 1,10 1,21 1,15 Dnmt3a BC089916 -1,32 -1,71 1,15 -1,14 1,44 Dnmt3a NM_001003957 -3,14 -3,16 -1,19 1,17 -1,04 Dnmt3b NM_001003959 2,36 2,17 -1,74 1,05 -1,47 Dnmt3l NM_001003964 -3,38 -2,09 1,83 1,02 1,73 Dnmt2 NM_001031643 -1,82 -1,14 -1,05 -1,01 -1,04 Dnmt1 NM_053354 -1,58 -1,34 1,39 1,19 1,78 similar to Dnmt3a XM_001069495 -1,45 -2,38 1,03 -1,37 2,58 Grhl1 XM_234006 HDACs Lung Liver Kidney Heart Placenta -1,59 -1,11 1,15 -1,15 1,25 Hdac3 BC061988 -1,66 -1,10 1,08 1,02 -1,25 Hdac5 BC086431 -4,86 -2,20 1,29 -1,10 1,11 Hdac10 BC092573 -1,16 1,00 -1,08 -1,09 1,30 Hdac1 BC107476 -1,12 1,07 -1,09 -1,05 1,30 Hdac1 NM_001025409 -1,51 -1,14 1,06 -1,19 1,36 Hdac3 NM_053448 -2,12 -1,70 1,04 -1,08 1,08 Hdac7a XM_001054796 -4,27 -1,88 1,25 -1,14 1,10 Hdac10 XM_001073452 -1,95 -1,36 -1,01 -1,10 1,30 Hdac6 XM_228753 -2,92 -1,88 1,22 -1,06 -1,09 Hdac11 XM_238362 1,84 1,00 1,04 1,16 -1,01 Hdac2 XM_342149 -2,80 1,08 1,20 -1,35 2,23 Hdac4 XM_343629 -2,95 -1,22 1,40 -1,19 1,65 Hdac8 XM_343804 1,88 1,52 -1,07 1,15 1,06 Hdac1 XM_576595 CHD Lung Liver Kidney Heart Placenta -1,81 2,10 -1,14 -1,11 7,09 Chd8 AF169825 -1,29 -1,08 1,96 -1,48 2,14 similar to testis-specific chromodomain Y-like protein NM_001014145 -1,60 -1,17 -1,24 -1,00 1,53 Chd4 XM_001067862 2,36 3,59 -1,58 1,24 1,37 similar to chromodomain helicase DNA binding protein 5 XM_001078944 3,00 5,25 -1,21 2,02 -1,32 similar to Probable chromodomain-helicase-DNA- binding protein KIAA1416 XM_001079582 -1,07 3,61 -1,05 1,02 2,88 Chd2 XM_218790 -1,57 -1,46 1,15 -1,23 -1,18 Chd3 XM_220602 2,00 -1,42 -1,29 1,09 -1,86 similar to Chromodomain-helicase-DNA-binding protein 1 XM_220804 -1,74 -2,51 1,09 -1,09 1,28 Cdyl2 XM_226510 e I: list of epigenetic regulators and their degree of alterations by induced IUGR
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Transcript of DNMTsLungLiverKidneyHeartPlacenta Gene nameAccession number -1,88-2,001,55-1,07-1,23...
DNMTs Lung Liver Kidney Heart Placenta Gene name Accession number
-1,88 -2,00 1,55 -1,07 -1,23 Dnmt3a-ps2 AB191343
-11,33 -7,02 1,10 1,21 1,15 Dnmt3a BC089916
-1,32 -1,71 1,15 -1,14 1,44 Dnmt3a NM_001003957
-3,14 -3,16 -1,19 1,17 -1,04 Dnmt3b NM_001003959
2,36 2,17 -1,74 1,05 -1,47 Dnmt3l NM_001003964
-3,38 -2,09 1,83 1,02 1,73 Dnmt2 NM_001031643
-1,82 -1,14 -1,05 -1,01 -1,04 Dnmt1 NM_053354
-1,58 -1,34 1,39 1,19 1,78 similar to Dnmt3a XM_001069495
-1,45 -2,38 1,03 -1,37 2,58 Grhl1 XM_234006
HDACs Lung Liver Kidney Heart Placenta
-1,59 -1,11 1,15 -1,15 1,25 Hdac3 BC061988
-1,66 -1,10 1,08 1,02 -1,25 Hdac5 BC086431
-4,86 -2,20 1,29 -1,10 1,11 Hdac10 BC092573
-1,16 1,00 -1,08 -1,09 1,30 Hdac1 BC107476
-1,12 1,07 -1,09 -1,05 1,30 Hdac1 NM_001025409
-1,51 -1,14 1,06 -1,19 1,36 Hdac3 NM_053448
-2,12 -1,70 1,04 -1,08 1,08 Hdac7a XM_001054796
-4,27 -1,88 1,25 -1,14 1,10 Hdac10 XM_001073452
-1,95 -1,36 -1,01 -1,10 1,30 Hdac6 XM_228753
-2,92 -1,88 1,22 -1,06 -1,09 Hdac11 XM_238362
1,84 1,00 1,04 1,16 -1,01 Hdac2 XM_342149
-2,80 1,08 1,20 -1,35 2,23 Hdac4 XM_343629
-2,95 -1,22 1,40 -1,19 1,65 Hdac8 XM_343804
1,88 1,52 -1,07 1,15 1,06 Hdac1 XM_576595
CHD Lung Liver Kidney Heart Placenta
-1,81 2,10 -1,14 -1,11 7,09 Chd8 AF169825
-1,29 -1,08 1,96 -1,48 2,14 similar to testis-specific chromodomain Y-like protein NM_001014145
-1,60 -1,17 -1,24 -1,00 1,53 Chd4 XM_001067862
2,36 3,59 -1,58 1,24 1,37
similar to chromodomain helicase DNA binding
protein 5XM_001078944
3,00 5,25 -1,21 2,02 -1,32
similar to Probable chromodomain-helicase-DNA-
binding protein KIAA1416XM_001079582
-1,07 3,61 -1,05 1,02 2,88 Chd2 XM_218790
-1,57 -1,46 1,15 -1,23 -1,18 Chd3 XM_220602
2,00 -1,42 -1,29 1,09 -1,86
similar to Chromodomain-helicase-DNA-binding
protein 1XM_220804
-1,74 -2,51 1,09 -1,09 1,28 Cdyl2 XM_226510
-2,26 -1,47 1,05 -1,10 1,36 similar to chromodomain Y-like protein 2 XM_226511
-1,54 -1,15 1,41 -1,06 1,44 Chd1l XM_227510
-1,26 -1,20 1,14 1,07 -1,01 Chd6 XM_230814
-2,37 -1,44 -1,07 -1,21 1,04
similar to chromodomain protein, Y chromosome-like
isoform a XM_231456
-3,40 -1,38 1,07 -1,17 1,94 Chd7 XM_232671
-1,06 2,98 -1,23 1,11 7,99 Chd1 XM_238731
-1,18 -1,13 -1,09 1,14 1,55 Chd8 XM_573762
BRD Lung Liver Kidney Heart Placenta
-1,79 -1,18 -1,94 1,85 -1,83 Brdt BC078999
-1,91 -1,62 1,31 -1,02 1,62 Brd8 NM_001008509
-1,18 -1,05 -1,06 -1,02 1,15 Brd2 NM_212495
-1,38 -1,15 1,02 1,03 1,28
similar to bromodomain and PHD finger-containing
protein 1 isoform 1XM_001054156
-1,09 -2,05 1,38 1,19 1,95 Brd4 XM_001065925
-1,69 -1,21 1,25 -1,08 1,51 Brd9 XM_217740
-2,10 -1,54 1,45 -1,15 2,85
similar to bromodomain and WD repeat domain
containing 2XM_219377
-1,13 1,04 1,13 -1,02 1,79 Brwd1 XM_221627
-2,64 -1,50 -1,33 -1,05 1,97 Baz2a XM_222315
-3,20 -1,15 1,13 -1,22 1,19 Brpf3 XM_228039
-2,92 -1,22 1,15 -1,05 3,25 Brwd3 XM_228518
-1,94 -2,35 1,75 1,11 4,69 Baz2b XM_229225
-1,58 -1,33 -1,03 -1,04 2,08 Baz1a XM_234156
-2,66 -1,08 -1,01 -1,14 1,67 Brd1 XM_235552
-1,02 -1,20 1,16 -1,03 1,29 Brd7 XM_341653
-1,10 -1,25 1,53 1,11 1,28 Brd3 XM_342396
-1,45 -1,12 1,01 -1,01 1,30 Baz1b XM_347166
3,55 1,50 -1,19 1,15 1,07 Brdt XM_573544
Histone
methyl/acetyl
transferase Lung Liver Kidney Heart Placenta
-1,23 2,00 -1,04 -1,07 2,56 Myst2 AY241457
1,69 1,02 1,39 1,19 1,69 Hat1 NM_001009657
-1,63 -1,10 1,31 -1,00 1,67 Myst1 NM_001017378
-1,31 -1,29 1,06 -1,08 1,48 Myst2 NM_181081
-1,74 -1,19 1,15 -1,22 -1,01 Ehmt2 NM_212463
-1,88 -1,16 1,12 1,04 1,91 similar to Histone acetyltransferase MYST4 XM_001067699
1,66 3,64 -1,33 1,21 -1,20
similar to Histone-lysine N-methyltransferase, H3
lysine-9 specific 4XM_001072340
1,14 2,86 -1,15 -1,15 4,09
similar to Histone-lysine N-methyltransferase, H3
lysine-9 specific 4 XM_001072375
-3,22 -1,72 -1,03 -1,26 1,59
similar to Histone-lysine N-methyltransferase, H3
lysine-4 specific SET7XM_001072672
-1,16 1,45 1,03 1,03 1,72 Myst3 XM_225008
-2,21 1,00 -1,01 -1,05 1,46 Ehmt1 XM_342379
-2,34 -1,15 -1,08 -1,09 1,42 Dot1l XM_343159
Supplementary Table I: list of epigenetic regulators and their degree of alterations by induced IUGR in the rat model.
