Director of Undergraduate Studies: Bernadette Holdener ...examination of case studies in science,...

BIOCHEMISTRY (BCH) Fall 2020 Bulletin

Biochemistry (BCH)Major in Biochemistry

Department of Biochemistry and Cell Biology; College of Arts and Sciences

Chair: Aaron NeimanDirector of Undergraduate Studies: Bernadette HoldenerEmail: [email protected] to the Chair: Carol JulianoOffice: 450 Life Sciences Building Phone: (631) 632-8550 Website: http://www.stonybrook.edu/commcms/biochem/

Minors of particular interest to students majoring in Biochemistry: Biomaterials (BES), Bioengineering (BNG), Chemistry (CHE)

Departments of Biochemistry and Cell BiologyThe Biochemistry Program

The Biochemistry Undergraduate Major Program provides a challenging and exciting introduction to the chemical basis of biological phenomena.

The major is designed to prepare students who intend to pursue graduate study, attend health-related professional schools, pursue secondaryschool teaching careers, and fill entry-level positions in private, state, and federal laboratories or in pharmaceutical and biotechnical industries.

The undergraduate curriculum provides a fundamental background in biology, chemistry, genetics, cell biology, and biochemistry, with courses inmathematics and physics necessary for advanced understanding of this broad field. Students may not declare a double major among biochemistry,biology, and pharmacology majors.

Requirements for the Major in Biochemistry (BCH)

All courses offered for the major must be taken for a letter grade. A minimum grade of C must be obtained in all courses in requirements A, B,and C below. Completion of the major requires approximately 70 to 74 credits.Transfer students who wish to complete the requirements for the Biochemistry major must take Biochemistry I and II (BIO 361and BIO 362)and must complete at least a minimum of nine additional credits at Stony Brook in required upper-division Biology courses (BIO 310, BIO 320,or BIO 365) and/or approved upper-division Biology elective courses. A. Courses in Related Fields

1. CHE 129/CHE 130, CHE 132 General Chemistry IA, II or CHE 131, CHE 132 General Chemistry IB, II or CHE 152 Molecular Science I 2. CHE 133, CHE 134 General Chemistry Laboratory or CHE 154 Molecular Science Laboratory I3. CHE 321, CHE 322 Organic Chemistry I, II or CHE 331, 332 Molecular Science II and III (See Note 1)4. CHE 327 Organic Chemistry Laboratory A or CHE 383 Introductory Synthetic and Spectroscopic Laboratory Techniques 5. CHE 301 or CHE 312 Physical Chemistry6. MAT 125, MAT 126, MAT 127 Calculus A, B, C or MAT 131, MAT 132 Calculus I, II or MAT 141, MAT 142 or MAT 171 or AMS 151

and AMS 161 or level 9 on mathematics placement examination. If students do not place into MAT 125 or 131 on the basis of the mathplacement examination, MAT 123 (or MAT 119/MAT 123) is a required course for the major.

7. PHY 121, PHY 122 Physics for the Life Sciences and Labs or PHY 125, PHY 126/PHY 133, PHY 127/PHY 134 Classical Physics A, B, Cand labs or or PHY 131 / PHY 133, PHY 132/PHY 134 Classical Physics I, II and labs or PHY 141/PHY 133, PHY 142/PHY 134 ClassicalPhysics I, II: Honors and labs

B. Core Courses in Biology

1. BIO 201 Fundamentals of Biology: Organisms to Ecosystems2. BIO 202 Fundamentals of Biology: Molecular and Cellular Biology3. BIO 203 Fundamentals of Biology: Cellular and Organ Physiology4. BIO 204 Fundamentals of Scientific Inquiry in the Biological Sciences I5. BIO 205 Fundamentals of Scientific Inquiry in the Biological Sciences II or BIO 207 Fundamentals of Scientific Inquiry in the Biological

Sciences II or IIB

C. Advanced Courses in Biology

1. EBH 302 Human Genetics or BIO 320 General Genetics or BIO 321 Ecological Genetics (see Note 2)2. BIO 310 Cell Biology3. BIO 361, BIO 362 Biochemistry I,II (see Note 1)4. BIO 365 Biochemistry Laboratory (fall only) 5. Two additional courses, totaling at least five credits, chosen after consultation with an advisor from the following list. It is highly

recommended that students take more than the suggested minimum number of electives

Stony Brook University: www.stonybrook.edu/ugbulletin 1


• AMS 333 Mathematical Biology• BIO 312 Bioinformatics and Computational Biology• BIO 314 Cancer Biology• BIO 315 Microbiology• BIO 316 Molecular Immunology• BIO 317 Principles of Cellular Signaling• BIO 321 Introduction to Ecological Genetics and Genomics (see Note 3)• BIO 325 Animal Development• BIO 327 Developmental genetics lab• BIO 328 Mammalian Physiology• BIO 332 Computational Modeling• BIO 334 Principles of Neurobiology• BIO 335 Neurobiology Laboratory• BIO 337 Neurotransmission and Neuromodulation: Implications for Brain Function• BIO 338 From Synapse to Circuit: Self organization of the Brain• BIO 339 Molecular Development of the Nervous System• BIO 350 Darwinian Medicine• BIO 354 Evolution• BIO 358 Biology of Human Social and Sexual Behavior• BIO 364 Laboratory Techniques in Cancer Biology• BIO 367 Molecular Diversity Laboratory• BME 304 Genetic Engineering• CHE 346 Bio-molecular Structure and Activity• EBH 302 Human Genetics (formerly offered as BIO 302 Human Genetics)• EBH 380 Genomics (formerly offered as BIO 304 Genomics)

Note 1. BIO 361 and BIO 362 must be taken in order. A grade of C or higher in BIO 202 and CHE 321 & CHE 326 or CHE 322is required toenroll in BIO 361 and BIO 362.Note 2. BIO 321 or EBH 302 can be used to satisfy EITHER the upper division BIO elective or the Genetics requirement (not both).

D. Upper-Division Writing Requirement

The advanced writing component of the major in Biochemistry requires registration in the 0-credit BIO 459 and approval of either a BIO 365laboratory report, or a manuscript written for a readings or research course in biology or chemistry at Stony Brook. To obtain approval, theoriginal graded writing sample and the writing requirement registration form, signed by both the student and instructor, should be submitted tothe Undergraduate Biology office. The Writing Center will evaluate the submission and contact the student directly if remedial efforts are needed.Students are urged to submit appropriate materials in their junior year, or by the end of their next-to-last term, in order to allow for evaluation andpossible revision. Later submissions are considered, but may delay graduation. If material is rejected, the student will be instructed by the WritingCenter before resubmitting the writing sample.

Students should consult with the department advisor to ensure that their plan for completing the Upper Division Writing Requirement isconsistent with university graduation requirements for General Education. Students completing the Stony Brook Curriculum (SBC) mustcomplete a course that satisfies the "Write Effectively within One's Discipline" (WRTD) learning objective to graduate. The Upper DivisionWriting Requirement is consistent in most cases with the SBC learning outcomes for WRTD.Honors Program in Biochemistry

Graduation with Honors in Biochemistry requires the following:1. A cumulative g.p.a. of at least 3.50 in all courses required for the major.2. Presentation of an acceptable thesis based on laboratory research project. Students interested in graduation with Honors must contact theBiochemistry Honors Coordinator for more detailed information no later that the second week of classes during their last semester.Bachelor of Science Degree in Biochemistry/Master of Science Degree in Chemistry ProgramA student interested in this research intensive graduate program, intended to prepare students for professional employment in the chemicalor pharmaceutical industries, may apply for admission at the end of the junior year. The program leads to a Bachelor of Science Degree inBiochemistry at the end of the fourth year, followed by a Master of Science in Chemistry at the end of the fifth year. During the senior year thestudent is expected to take two 500-level CHE courses and begin research. In the fifth year, the student works full-time on research, earning24 credits in CHE 599. The two 500-level CHE courses taken during the senior year may be counted toward the two electives required by theBiochemistry major. Please visit the Chemistry website http://stonybrook.edu/chemistry for further information on the Chemistry graduatedegree.

Sample Course Sequence for the Major in Biochemistry



A course planning guide for this major may be found here. The major course planning guides are not part of theofficial Undergraduate Bulletin, and are only updated periodically for use as an advising tool. The UndergraduateBulletin supersedes any errors or omissions in the major course planning guides.

FRESHMAN

FALL Credits

First Year Seminar 101 1

WRT 101 3

CHE 131/CHE 133 5

MAT 125 or MAT 131 3-4

SBC 3

Total 15-16

SPRING Credits

First Year Seminar 102 1

WRT 102 3

BIO 201 or BIO 202 3

CHE 132/CHE 134 5

MAT 126 or MAT 132 3-4

Total 15-16

SOPHOMORE

FALL Credits

BIO 203 3

CHE 321 4

MAT 127 (if MAT 125, MAT 126, MAT 127 sequence taken) 3

BIO 204 2

BIO 458 0

SBC 3

Total 15

SPRING Credits


CHE 322 4

CHE 327 2


SBC 3

Total 14

JUNIOR

FALL Credits

BIO 361* 3

PHY 121 4

BIO 365 2

BIO 459 0



SBC 3

SBC 3

Total 15

SPRING Credits

BIO 362* 3

BIO 320 3

PHY 122 4

SBC 3

SBC 3

Total 16

SENIOR

FALL Credits

BIO elective*** 3

SBC or BIO elective*** 3

SBC 3

SBC 3

SBC 3

Total 15

SPRING Credits

BIO 310 3

CHE 312** 3

BIO elective*** 3

SBC 3

SBC 3

Total 15

*BIO 361 and 362 should be taken in sequence.

**Physical Chemistry I (CHE 301) or Physical Chemistry (short course) (CHE 312) may be taken to fulfill the one semester Biochemistry Majorphysical chemistry requirement. CHE 301 is offered only in the fall but has very limited enrollment capacity; CHE 312 is offered only in thespring.

***Two BIO electives are required for the major and must be chosen from the approved list.Electives not on the list must be approved by a Biochemistry major.


BIOCHEMISTRY (BCH) - COURSES Fall 2020 Bulletin

BIOBiology

BIO 103: Introduction to Biotechnology

Gene therapy, genetic modification, cloning,stem cells, and vaccines are covered in thiscourse. Lectures and four supplementallaboratory activities use modern equipmentand techniques to illustrate core conceptswhich class discussions relate to health,society, and public policy. Not for Biologymajor credit.

DEC: ESBC: SNW

3 credits

BIO 104: How Science Works

The course aims at expanding students'knowledge about the methods of the naturalsciences and to develop the critical thinkingabilities to understand scientific claimspresented by the media. Students willlearn about scientific discoveries as wellas the differences between science andpseudoscience. The course includes lecturesand discussions based on textbook material,examination of case studies in science, anddiscussion of items in the news. Not forBiology major credit.

DEC: ESBC: SNW

3 credits

BIO 113: General Ecology

A survey of the principles of ecology in thecontext of finding solutions to local, national,and global environmental problems. Not forBiology major credit.

DEC: ESBC: SNW

3 credits

BIO 114: Dinosaur Paleontology

A study of paleontology that includesevolution of dinosaurs, their classificationsystem, a study of the important dinosaurfamilies, dinosaur behavior, ecology,current controversies, hot topics and the KTextinction. Dinosaur paleontology will alsocover the excavation of dinosaurs and thecolorful history of the 'dinosaur hunters.'This course will emphasize the science andresearch involved in studying dinosaurs.Using dinosaurs as a vehicle, students will beexposed to the scientific method of inquiryand will leave this course with a betterunderstanding on how to evaluate science inthe real world. Not for Biology major credit.

Advisory prerequisite: Entry level biology

DEC: ESBC: SNW

3 credits

BIO 115: Evolution and Society

An introduction to the historical andtheoretical aspects of evolutionary biology,and also considers the implications ofevolution for current social and publicissues. The course examines both the originalDarwinian and Modern Synthetic argumentsfor evolution by natural selection, how todifferentiate scientific and non-scientifictheories, and how historical sciences arepracticed by scientists. Evolution is the key tounderstanding much of biology and influencesa number of issues that we as citizens will haveto consider in coming years. In particular, theevolutionary perspective and its implicationsfor the development of humans and othersocial systems, the advent of agriculture,and its integral role in human health areconsidered. Not for Biology major credit.

DEC: ESBC: SNW

3 credits

BIO 201: Fundamentals of Biology:Organisms to Ecosystems

An introduction to the major concepts inevolution, ecology, and biodiversity atthe genetic, organismal, community, andecosystem levels. Topics are presented inrelation to five overall themes: Nature andProcess of Science, Evolution, InformationFlow, Systems, and Structure-Function. Thiscourse has been designated as a High Demand/Controlled Access (HD/CA) course. Studentsregistering for HD/CA courses for the firsttime will have priority to do so.

Prerequisite: Level 4 or higher on themathematics placement examination orCorequisite MAT 123 or higherAdvisory Prerequisite: High School Biology

DEC: ESBC: SNW

3 credits

BIO 202: Fundamentals of Biology:Molecular and Cellular Biology

The fundamentals of cell biology,biochemistry, and genetics. The biochemicaland molecular bases of cell structure, energymetabolism, gene regulation, heredity, anddevelopment in living organisms from bacteriato man are discussed. This course has beendesignated as a High Demand/ControlledAccess (HD/CA) course. Students registering

for HD/CA courses for the first time will havepriority to do so.

Prerequisite: C or higher in CHE 129 or CHE131 or Corequisite CHE 152

DEC: ESBC: STEM+

3 credits

BIO 203: Fundamentals of Biology:Cellular and Organ Physiology

The fundamentals of cell and organ physiologyin mammalian and non-mammalian organisms.The structure and function of cell membranesand the physiology of cell to cell signaling,cellular respiration, and homeostasis oforgans and organisms are examined with anemphasis on the comparative physiology ofvertebrates and invertebrates. This course hasbeen designated as a High Demand/ControlledAccess (HD/CA) course. Students registeringfor HD/CA courses for the first time will havepriority to do so.

Prerequisite: C or higher in CHE 129 or CHE131 or Corequisite CHE 152Pre- or Corequisite: MAT 125 or higher orAMS 151

DEC: ESBC: STEM+

3 credits

BIO 204: Fundamentals of ScientificInquiry in the Biological Sciences I

First course in the foundational laboratorysequence for all biology students, and studentsin related fields. Students will experiencethe laboratory process, research process, awide range of laboratory tools, methods,skills, learn to read and write scientificpresentations, and collaborate in formalinquiry. This course has been designatedas a High Demand/Controlled Access (HD/CA) course. Students registering for HD/CAcourses for the first time will have priority todo so. This course has an associated fee. Pleasesee www.stonybrook.edu/coursefees for moreinformation. This course includes assignmentsthat can be used to satisfy the SBC objectiveSPK if co-registered for BIO 458.

Prerequisite: C or higher in CHE 129, CHE131, or Corequisite: CHE 152Pre- or Corequisite: BIO 201 or BIO 202 orBIO 203

2 credits

BIO 205: Fundamentals of ScientificInquiry in the Biological Sciences IIA

Second course in the foundational laboratorysequence for all biology students, and studentsin related fields. Students will experience thelaboratory process, research process, a wide



range of laboratory tools, methods, skills, learnto read and write scientific presentations, andcollaborate in formal inquiry. This course hasbeen designated as a High Demand/ControlledAccess (HD/CA) course. Students registeringfor HD/CA courses for the first time will havepriority to do so. Not for credit in addition toBIO 207. This course has an associated fee.Please see www.stonybrook.edu/coursefees formore information.

Prerequisite: BIO 204Pre- or Corequisite: BIO 201 or BIO 202 orBIO 203

2 credits

BIO 207: Fundamentals of ScientificInquiry in the Biological Sciences IIB

An alternative to BIO 205, this course focuseson a relatively narrow range of currentresearch topics but in greater depth. BIO207 is the second course in the foundationallaboratory sequence for all biology majorsand students in related fields. Students willexperience the laboratory process, researchprocess, a wide range of laboratory tools,methods, and skills, learn to read and writescientific works, and collaborate in formalinquiry. This course has been designatedas a High Demand/Controlled Access (HD/CA) course. Students registering for HD/CAcourses for the first time will have priority todo so. Not for credit in addition to BIO 205.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: BIO 204Pre- or Corequisite: BIO 201 or BIO 202 orBIO 203

2 credits

BIO 208: Cell, Brain, Mind

An introduction to the human brain andhow it is the target of diseases, drugs, andpsychological disturbances. The courseexplores these topics through a knowledge ofbasic cell neurobiology. The implications ofbrain science for human behavior in society arealso considered. Not for major credit.

Advisory Prerequisite: High school chemistry

DEC: HSBC: STAS

3 credits

BIO 211: Statistics and Data Analysis:A Conceptual Approach

A conceptually-focused introduction toprobability and data analysis emphasizingstatistical literacy and critical thinking. Topicswill include probability, t-tests, chi-squaredtests, correlation, regression, and Analysis ofVariance, as well as special topics of interest

to undergraduate Biology majors such ascase-control studies and meta-analysis. Thiscourse includes a one-hour recitation in whichstudents will do hands-on activities, discusspapers from the primary literature, and gainexperience with data analysis. May not betaken by students with credit for AMS 110,310, 311, 412, EBH 230, or ECO 320.

Pre- or Corequisite: MAT 123 or higher,or level 4 or higher on the mathematicsplacement examination. May not be taken bystudents with credit in AMS 110, 310, 311,412, EBH 230, or ECO 320

DEC: CSBC: STEM+

4 credits

BIO 231: Cannabis: History, Culture,Science & Medicinal Uses

Provide a sound background in all aspectsof cannabis, including the history ofuse worldwide, cannabis plant biology,the chemistry of cannabinoids andendocannabinoids, and the relationship topolitical, legal, and racism issues throughouthistory to the present. The purpose of thisbroad familiarization is to prepare students tocontribute knowledgeably to the discussionand debate regarding the present and futureuses of cannabis.

Advisory prerequisites: BIO 202

SBC: STAS

3 credits

BIO 299: Advanced Microbiology forNursing and Allied Health

This course will include lectures, laboratoryrecitations, and laboratory sessions focusedon fundamental clinical Microbiologytechniques. The lectures will cover Bacteria,Viruses, Helminths, and medically importantProtozoans. In the laboratory, students willlearn basic and applied clinical microbiologymethods, including microscopy; staining andquantitative analysis of bacteria; analysis ofthroat and urine cultures; and determinationof sensitivity to various antimicrobial agents.Priority for this course will be given toallied health, pre-nursing, and pre-veterinarystudents. May not be used for credit towardseither the Biology major or minor. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation. Formerly offered as BIO 266; notfor credit in addition to BIO 266.

Prerequisite: C or higher in BIO 202 and BIO204

4 credits

BIO 306: Principles of Virology

Covers the principles of virology, focusingmainly on animal and human viruses, but alsoincluding plant viruses and bacteriophage.Topics include the classification of viruses,virus entry, genome replication and assembly,and viral pathogenesis. Particular emphasisis placed on virus-host cell interactions andcommon features between different virusfamilies. Recommended for those planningto attend medical school, graduate schoolor Veterinary college, or anyone who isinterested in what viruses are and how theycause disease.

Prerequisite: C or higher in BIO 202

SBC: ESI, STEM+, WRTD

3 credits

BIO 310: Cell Biology

The cell is studied as the unit of structure,biochemical activity, genetic control, anddifferentiation. The principles of biochemistryand genetics are applied to an understanding ofnutrition, growth, and development.

Prerequisites: C or higher in BIO 202; C orhigher in BIO 203; CHE 321 or CHE 331 orCHE 341

3 credits

BIO 312: Bioinformatics andComputational Biology

This course uses computational methods toanalyze current problems and solutions inmolecular biology research. Students areexposed to algorithms and tools availablefor both single gene and larger scale genomeresearch. Emphasis is on practical application.Laboratories allow students to apply theirknowledge to real life molecular biologyproblems.

Prerequisites: C or higher in BIO 202; and Cor higher in BIO 204; and MAT 125 or higheror AMS 151Advisory Pre- or Corequisite: AMS 110, orBIO 211

SBC: ESI, TECH

3 credits

BIO 314: Cancer Biology

An examination of the biology of cancer.Emphasis is on molecular and cellularevents, such as regulation of gene expression,genome maintenance, cell growth and death,differentiation, cell-cell recognition, signalingand homeostasis that are frequently disruptedin cancer. Recent advances in diagnosis andtherapy will also be discussed.


3 credits

BIO 315: Microbiology



The organization, structure, energetics, andreproduction of microorganisms. Interactionsof bacteria and viruses are discussed.This course does not include a laboratorycomponent. Not for credit in addition to HBM320. This course has been designated as a HighDemand/Controlled Access (HD/CA) course.Students registering for HD/CA courses for thefirst time will have priority to do so.

Prerequisites: C or higher in BIO 202Advisory Pre- or Corequisite: BIO 201

3 credits

BIO 316: Molecular Immunology

Structure, function, and organization ofthe immune response at the molecular andcellular levels. Molecular mechanisms ofimmunological responses to microorganismsand various disease states are explored.

Prerequisites: BIO 202 and BIO 203Pre- or corequisite: CHE 322 or CHE 326 orCHE 332

3 credits

BIO 317: Principles of CellularSignaling

Basic principles of cellular signaling andmaintenance of cellular and organismichomeostasis through intra- and intercellularsignaling mechanisms. The roles of membraneand nuclear receptors, second-messengerpathways and gene regulation in controllingdiverse mammalian systems such as sensoryphysiology, organic metabolism, growthcontrol, and neuronal development arediscussed.

Prerequisite: C or higher in BIO 202Advisory Prerequisite: BIO 203

3 credits

BIO 319: Landscape EcologyLaboratory

A computer lab course focusing on spatialconcepts, methods, and tools for addressingecological and environmental problems.The course will be based on fundamentalconcepts in ecology and environmentalscience and extend that knowledge, as wellas teaching technical skills, including theuse of geographic information systems(GIS) software, image processing, spatiallyexplicit modeling, and spatial statistics.The lab exercises will introduce a varietyof spatial approaches addressing problemsin environmental protection, ecotoxicology,natural resource management, conservationbiology, and wildlife management.

Pre- or Corequisite: BIO 201Advisory Prerequisites: AMS 110 or BIO 211;BIO 351

SBC: ESI

3 credits

BIO 320: General Genetics

Integrates classical and molecular approachesto the transmission and expression ofbiological information. Topics include:Mendelian and non-Mendelian inheritance;linkage analysis; population genetics; DNAreplication, mutation and recombination;gene expression and its regulation; currentgenetic technology; developmental and cancergenetics, quantitative and complex traits, andrelevant ethical issues.

Prerequisite: C or higher in BIO 202; and Cor higher in MAT 125

3 credits

BIO 321: Ecological Genetics

An introduction to the concepts, researchquestions, and methods involved in modernecological genetics. The goal of the course isto provide a broad conceptual framework andan introduction to basic quantitative methodsfor students planning to engage in empiricalwork in conservation, management, ecology,and evolutionary biology. The course willcover basic Mendelian genetics, meiosis, andmating systems, standard population geneticsmethods for describing variation withinand between populations, basic quantitativegenetics, methods for molecular markergenotyping, informatic and genomic concepts,and organism-specific methods and casestudies.

Prerequisites: C or higher in BIO 201 and Cor higher in BIO 202Advisory Pre- or Corequisite: BIO 351

3 credits

BIO 325: Animal Development

An overview of animal embryonicdevelopment, emphasizing molecularmechanisms regulating embryonic growthand differentiation. General areas to bediscussed include: molecular basis of humanbirth defects, stem cells, identification ofdevelopmental genes, establishing polarityin Drosophila and vertebrates, regulation ofcell differentiation, morphogenesis and organdevelopment, development of cancer.


3 credits

BIO 327: Developmental GeneticsLaboratory

Exploration of the fundamental conceptsin developmental biology and geneticsthrough a combination of classical andmodern molecular genetic approaches.Experiments are conducted using Xenopus

and Drosophila, two important animalmodels for research in developmentalbiology and genetics. Students gain hands-on experience with the approaches used toinvestigate processes that control embryonicdevelopment on these two model systems,including the use of modern molecularmethods for examining the regulation of geneexpression during development. Exposure tothe genetic approaches that are available in theDrosophila system will include participationin a genetic screen for new mutations. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation. This course includes assignmentsthat can be used to satisfy the SBC objectiveSPK if co-registered for BIO 458.

Prerequisites: BIO major with DevelopmentalGenetics Specialization or departmentalpermission; C or higher in BIO 325; C orhigher in BIO 205 or BIO 207Pre- or Corequisite: BIO 320 or BIO 321

SBC: ESI

3 credits

BIO 328: Mammalian Physiology

A continuation of the fundamental principlesof cellular and organ physiology introducedin BIO 203. The subject matter includesadvanced topics covering the origins ofmembrane potentials, describing propertiesof synaptic transmission, identifying thegenetics and consequences of channelopathiesin cellular and organ cardiac physiology,and advanced treatment of selected topicsin endocrine, cardiac, respiratory, renal andnervous system physiology. The focus ison mammals in general and humans moreparticularly. May not be taken for credit inaddition to HBY 350.

Prerequisite: C or higher in BIO 203Advisory Prerequisite: CHE 132 or CHE 142or CHE 331

3 credits

BIO 332: Computational Modeling ofPhysiological Systems

Introduces students to the fundamentalprinciples underlying computational modelingof complex physiological systems. A majorfocus of the course will be on the processby which a model of a biological system isdeveloped. Students will be introduced tothe mathematical methods required for themodeling of complex systems (includingstochastic processes and both temporal andspatial dynamics) as well as to tools forcomputational simulation. Roughly one halfof the class will focus on models for generalcellular physiology, while the remaining halfwill focus on the development of higher-



level models of a particular physiologicalsystem (for example, the neurobiologicalsystems underlying learning). This courseis offered as both AMS 332 and BIO 332and is intended for STEM majors who havealready completed the foundational coursesin their major. Students who satisfy the pre-requisites but do not have a deeper backgroundin some STEM field may find the class verychallenging and should ask the instructor forguidance before registering.

Prerequisite: MAT 127 or MAT 132 or higherand any one of the following: BIO 202 or BIO203 or CHE 132 or CHE 331 or PHY 127 orPHY 132

3 credits

BIO 334: Principles of Neurobiology

The ionic basis of nerve potentials, thephysiology of synapses, sense organs andeffectors, and the integrative action of thenervous system are discussed.


3 credits

BIO 335: Neurobiology Laboratory

A laboratory course in physiology witha focus on neuromuscular function.Topics include acquisition and analysis ofelectrophysiological data; ion channels,electrical excitability and action potentials;synaptic transmission and muscularcontraction; development of physiologicalfunctions; central control of movement;sensory function and behavior; cardiacfunction and regulation; and ethical andpolitical issues of physiological relevance.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: BIO major with NeuroscienceSpecialization or departmental permission; Cor higher in BIO 203; C or higher in BIO 205or 207 and the following: PHY 122/PHY 124or PHY 127 or PHY 132

SBC: ESI

3 credits

BIO 336: Conservation Biology

Society and individual lives are increasinglyaffected by environmental degradation atdifferent scales. From the decline of localfisheries to global climate change, multiplecrises threaten the biodiversity and ecosystemsthat sustain us humans. This course introducesthe scientific foundations of conservationbiology, along with examples from real-world conservation. The course reviews thebiological concepts that underlie conservationincluding habitat requirements, populationdynamics, biogeography, and population

genetics. Analysis of case studies on theeffects of human activities on biologicaldiversity and ecosystem services will be usedto explore the interdisciplinary nature of thepractice of conservation. This course willprepare students for careers in environmentalsciences and ecology.

Prerequisite: C or higher in BIO 201Advisory Pre- or Corequisite: BIO 320 or BIO321; BIO 351

DEC: HSBC: STAS

3 credits

BIO 337: Neurotransmission andNeuromodulation: Implications forBrain Function

Exploration of fundamental concepts ofneurotransmission and neuromodulation ofsynaptic transmission. The subject matterincludes an overview of the basic principles ofneurotransmission and of the neuromodulatorysystems in the brain. The involvement of thesesystems in behavior and neurological disordersis emphasized. We will discuss how specificneurological disorders can be investigatedexperimentally and how experimental resultscan contribute to understanding and treatingthese disorders.


3 credits

BIO 338: From Synapse to Circuit: Self-organization of the Brain

Exploration of basic neural and synapticmechanisms and the operation ofrepresentative brain circuits, using boththeoretical approaches and experimentalevidence. Particular attention is givento Hebb's Rule, its cellular basis, itsconsequences for circuit selforganization,and its limits. A solid background in amathematical, physical, or biological scienceis desirable, but most relevant backgroundmaterial is covered in the course.

Prerequisite: Instructor permission and BIO203 or CHE 132 or CHE 331 or PHY 122Advisory Prerequisite: BIO 334

3 credits

BIO 339: Molecular Development of theNervous System

An introduction to the molecular events thatunderlie development and plasticity of both theperipheral and central nervous systems, with afocus on neuronal mechanisms. Molecular andgenetic approaches to the analysis of neuralinduction, neuronal differentiation, neuronaldeath and survival, neurotrophic factors,synapse formation and plasticity are presented.

Prerequisite: C or higher in BIO 202 or BIO203

3 credits

BIO 341: Plant Diversity

An introduction to the study of plants,especially green plants, including the originand evolution of land plants. Topics includecellular structure and function, photosynthesisand respiration, gross anatomy, taxonomyand the diversity of organisms, plant ecology,agriculture. Three hours of lecture andone three-hour laboratory per week. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisites: BIO 201; BIO 202; BIO 204

4 credits

BIO 342: Invertebrate Zoology

Aspects of the diversity, comparative andfunctional morphology, natural history,evolution, and water-land transitions ofinvertebrate animals. Three hours of lectureper week. Must be taken concurrently with theInvertebrate Zoology Laboratory, BIO 343.

Prerequisite: C or higher in BIO 201 or MAR104; BIO 204Corequisite: BIO 343

SBC: STEM+

3 credits

BIO 343: Invertebrate ZoologyLaboratory

Aspects of the diversity, comparative andfunctional morphology, natural history,evolution, and water-land transitionsof invertebrate animals. One three-and-one-half hour laboratory per week plus arecitation. Must be taken concurrently withthe Invertebrate Zoology lecture, BIO 342.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation

Prerequisites: C or higher in BIO 201 or MAR104; and BIO 204Corequisite: BIO 342

2 credits

BIO 344: Chordate Zoology

Introduction to the diversity, natural history,and evolution of chordates, emphasizing theliving vertebrates. Three hours of lecture ordiscussion and one three-hour laboratory perweek. This course has an associated fee. Pleasesee www.stonybrook.edu/coursefees for moreinformation.

Prerequisite: BIO 201

4 credits



BIO 347: Introduction to NeuralComputation

A broad introduction to neural computation.This course will discuss what counts as'computation' and in what sense the braincomputes, how it computes, and whetherthose computations look anything likethose performed by digital computers.These ideas and concepts will be introducedthrough examples of computation in thebrain, including the neural bases of sensoryperception, decision making, learning andmemory, and motor control. Students willlearn through in-class demonstrations andactivities, as well as homework assignmentsthat give students the opportunity to analyzereal neural recordings relevant to each of thetopic modules.

Prerequisite: MAT 126, MAT 132, or higher;BIO 211, AMS 110, or AMS 310; any oneof BIO 202, BIO 203, CHE 132, CHE 331,PHY 127 or PHY 132. It is recommended thatstudents take MAT 127.

SBC: STEM+

3 credits

BIO 348: Diversity and Evolution ofReptiles and Amphibians

The course will survey the diversity andnatural history of the major groups of reptilesand amphibians, including snakes, lizards,turtles, crocodilians, frogs, and salamanders.Extinct groups (such as dinosaurs andpterosaurs) will also be covered. Furthermore,the course will showcase how studies ofreptiles and amphibians have increased ourgeneral understanding of evolution andecology, and will illustrate how diverse aspectsof organismal biology (such as physiology,ecology, behavior, morphology) evolve and areinterconnected.

Prerequisite: BlO 201

3 credits

BIO 350: Darwinian Medicine

The ecology and evolution of disease,including evolution of human resistance toinfection by pathogens, pathogen evolutionin response to natural and technologicaldefenses, and the ecological context of disease.Evolutionary phenomena are treated frommolecular, organismal, population, andenvironmental perspectives.

Prerequisite: C or higher in BIO 201 and C orhigher in BIO 202

DEC: HSBC: STAS

3 credits

BIO 351: Ecology

An examination of the interactions of livingorganisms with their physical and biologicalenvironments. Special attention is given topopulation dynamics and the interactionsamong organisms that determine the structure,function, and evolutionary development ofbiological communities.

Prerequisite: C or higher in BIO 201 orpermission of instructor

DEC: HSBC: STEM+

3 credits

BIO 352: Ecology Laboratory

Stresses the collection, analysis, andinterpretation of ecological data, mostlyin terrestrial settings. Laboratory and fieldexercises demonstrate the operation ofgeneral ecological principles in specificpopulations and communities. One lecture,one three-hour field trip or laboratory,and one hour of recitation per week. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: BIO 205 or BIO 207Pre- or Corequisite: BIO 351 or permission ofinstructor

SBC: ESI

3 credits

BIO 353: Marine Ecology

A survey of biotic responses to ecologicalchallenges in different marine realms. Controlsof diversity and trophic structure in the marineecosystem, historical aspects of marine realms,productivity in the oceans, plankton, soft-bottom communities, intertidal habitats, coralreefs, deep-sea environments, and effects ofpollution in the ocean are discussed.

Prerequisite: C or higher in BIO 201 or MAR104Advisory Prerequisite: BIO 343

SBC: STEM+

3 credits

BIO 354: Evolution

A detailed discussion of the mechanisms ofevolution, focusing on the ways in whichgenetic changes in populations lead toadaptation, speciation, and historical patternsof evolutionary change.

Prerequisites: C or higher in BIO 201 and BIO202Advisory pre- or corequisite: BIO 320 or 321

3 credits

BIO 356: Applied Ecology andConservation Biology Laboratory

A computer laboratory course introducingstudents to ecological risk analysis andconservation biology. Laboratories are basedon interactive software. Computer simulationtechniques for addressing problems in appliedecology are emphasized.

Prerequisite: BIO 201, BIO 202, or BIO 203;BIO 204; MAT 126 or higher

SBC: ESI

2 credits

BIO 358: Biology and Human Socialand Sexual Behavior

Major features of human social and sexualbehavior are examined from a biologicalperspective. Insights from ethology,evolutionary biology, and neurobiology aresynthesized into a picture of human natureand behavior. Implications of this picturefor human sexual and social behavior areconsidered. This course has been designatedas a High Demand/Controlled Access (HD/CA) course. Students registering for HD/CAcourses for the first time will have priority todo so.

Prerequisites: U3 or U4 standing; and one ofthe following: ANP 101, BIO 115, BIO 201,BIO 202, or BIO 203

DEC: HSBC: ESI, STAS

3 credits

BIO 361: Biochemistry I

First course of an advanced two-semesterstudy of the major chemical constituents ofthe cell, including carbohydrates, lipids, andproteins. Emphasis is on enzyme structure,enzyme kinetics, reaction mechanisms, andmetabolic pathways.

Prerequisite: C or higher in BIO 202 and C orhigher in CHE 322 or 332 or 326

3 credits

BIO 362: Biochemistry II

Second course of an advanced two-semesterstudy of biochemistry. BIO 362 is theMolecular Biochemistry section that treatsnucleic acid structure, replication, andtranscription, both in vivo and in vitro. Themachinery and regulation of prokaryotic andeukaryotic protein synthesis is also covered,including amino acid activation; transfer RNA;ribosomes; the genetic code; and peptide chaininitiation, elongation, and termination.

Prerequisites: C or higher in BIO 361 or CHE346

3 credits

BIO 364: Laboratory Techniques inCancer Biology



This course will introduce contemporaryconcepts of cancer initiation, progression,metastasis and therapy. The lectures andrecitations will include discussions ofappropriate review articles, textbookreadings and research articles. In thelaboratory, students will be introduced toand recapitulate key techniques used in theselected research articles. This course willrequire significant work on computers outsideof class time (more than 3 hours per week).This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: BIO Major or departmentalpermission; C or higher in BIO 205 or BIO207Pre- or corequisite: BIO 314, C or higher ifused as a prerequisite

3 credits

BIO 365: Biochemistry Laboratory

Biochemistry 365 Laboratory is divided intofour modules. They include: (1) classicalbiochemistry techniques to extract andquantify cellular constituents such aschlorophyll, DNA, RNA and proteins inEuglena gracilis, (2) the study of bovinecatalase enzyme kinetics and the studentsdesign an experiment to measure their bloodcatalase, (3) the purification of a His-taggedprotein and the evaluation of its purity withSDS gel electrophoresis and western blotanalysis and (4) students' amplifying theirmitochondrial control region DNA by PCR forsequencing and comparing their sequence toknown sequences dating back to the earliesthominids, in terms of the evolutionary tree.These experiments are designed to teach basicbiochemistry techniques as well as developthe skills of problem solving and analyticalthinking. This course has an associated fee.Please see www.stonybrook.edu/coursefees formore information.

Prerequisite: BCH, BCP or BIO Major ordepartmental permission; C or higher in BIO205 or BIO 207Pre- or corequisite: BIO 310 or BIO 361

SBC: ESI

2 credits

BIO 366: Molecular MicrobiologyLaboratory

This course will include both lectures as welllaboratory sessions focused on conventionaland contemporary Molecular Microbiologicaltechniques. The lectures will cover a varietyof microorganisms; Bacteria, Fungi, Viruses,and Protozoans based on textbook readingsand current research articles. In the laboratory,students will learn fundamental and applied

microbiological methods, biochemicaland DNA profiling of microorganisms,and the molecular basis of physiologicalprocesses used for the identification ofunknown bacteria. This course will serve asan upper-division elective for BIO majors.The course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: BIO major; C or higher in BIO205 or 207; C or higher in BIO 315

4 credits

BIO 367: Molecular DiversityLaboratory

Hands-on experience with methods todetect and analyze molecular (DNA,RNA, protein) variation to study ecology,adaptation, and evolutionary history usingnatural populations of Drosophila, plankton,and other locally available species. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisites: C or higher in BIO 201; C orhigher in BIO 202; BIO 205 or BIO 207Advisory Pre- or Corequisite: One of thefollowing: BIO 320, BIO 321, BIO 351, or BIO354

3 credits

BIO 368: Food Microbiology

This course is designed to give students anunderstanding of subtle relationship betweenfood borne microorganisms and human health.Course will cover various topics focused onmicroorganisms involved in food processing,preservation, spoilage, and methods to controltheir growth in food items. The lectures willbe presented based on textbook readings andcurrent research articles and cover in depth therole of food borne microorganisms in illness aswell health promotion. This course will serveas an upper-division elective for BIO majors.


2 credits

BIO 371: Restoration of AquaticEcosystems

A field and laboratory course designedto introduce students to field methods inassessing the long-term effects of pollutionand restoration of aquatic and marsh systems.Students will work in teams to collaborate onmeasuring exchange of pollutants between arestored Superfund site and adjacent areas,the long-term effects of ecological restoration,habitat assessment, aquatic communitystructure in restored and adjacent systems,and long-term evolutionary effects on aquaticpollutants. Other restoration systems will be

compared. This course has an associated fee.Please see www.stonybrook.edu/coursefees formore information.

Prerequisites: BIO 201; BIO 202; BIO 204Advisory Prerequisite: BIO 353

DEC: HSBC: STAS

4 credits

BIO 380: Entomology

A survey of the anatomy, development,classification, biogeography, physiology,ecology, and evolution of the insects. Thelaboratory stresses a knowledge of insectdiversity and morphology. Three hours oflecture and three hours of laboratory per week.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisites: C or higher in BIO 201; BIO202; BIO 204

4 credits

BIO 385: Plant Ecology

Basic ecological principles as applied tothe biology of individual plants, plantpopulations, communities, and ecosystemsin relation to their environments. Examplesfrom Long Island pine barrens, tropical rainforests, beaches, deserts, and other plantcommunities are studied. Examination of theconnections between human societies and plantcommunities, which are rapidly being alteredor destroyed worldwide.

Prerequisite: C or higher in BIO 201Advisory Pre- or Corequisite: BIO 351

DEC: HSBC: STAS

3 credits

BIO 386: Ecosystem Ecology and theGlobal Environment

Ecosystem ecology with an emphasis onbiogeochemical cycling in oceans and onland, as well as on biosphere-atmosphereinteractions. Topics include earth systemprocesses such as climate and atmosphericcomposition, the hydrological cycle, cyclingof chemicals such as nutrients and metals inthe oceans, the soil cycle, and the fate andtransport of materials in the atmosphere.Natural and perturbed systems are discussed.This course is offered as both BIO 386 andENS 311.

Prerequisites: C or higher in BIO 201; CHE129 or CHE 131 or CHE 141 or CHE 152Advisory Prerequisite: MAR 104

DEC: HSBC: STAS



3 credits

BIO 444: Experiential Learning

This course is designed for students whoengage in a substantial, structured experientiallearning activity in conjunction with anotherclass. Experiential learning occurs whenknowledge acquired through formal learningand past experience are applied to a "real-world" setting or problem to create newknowledge through a process of reflection,critical analysis, feedback and synthesis.Beyond-the-classroom experiences thatsupport experiential learning may include:service learning, mentored research, fieldwork, or an internship.

Prerequisite: WRT 102 or equivalent;permission of the instructor andapproval of the EXP+ contract (http://sb.cc.stonybrook.edu/bulletin/current/policiesandregulations/degree_requirements/EXPplus.php)

SBC: EXP+

0 credit, S/U grading

BIO 446: Readings in Neurobiology andPhysiology

Tutorial readings in the biological sciences.These courses may be repeated, but not morethan two credits may be used toward biologymajor requirements. Limit of one topic persemester.

Prerequisite: Undergraduate Biology programapproval and permission of instructor

SBC: ESI

1-2 credits, S/U grading

BIO 447: Readings in Molecular,Cellular, and Developmental Biology



SBC: ESI


BIO 449: Readings in Ecology andEvolution



SBC: ESI


BIO 458: Speak Effectively Before anAudience

A zero credit course that may be takenin conjunction with any BIO course thatprovides an opportunity to achieve the learningoutcomes of the Stony Brook Curriculum'sSPK learning objective.

Corequisite: BIO 204 or BIO 311 or BIO 327or BIO 486 or BIO 487 or BIO 488 or BIO 489or departmental permission

SBC: SPK


BIO 459: Write Effectively in Biology

A zero credit course that is taken in associationwith a 300- or 400-level BIO course thatprovides opportunity to achieve the learningoutcomes of the Stony Brook Curriculum'sWRTD learning objective. For informationon approved co-requisite courses and theregistration form for Biology and Biochemistrymajors see: http://www.stonybrook.edu/commcms/biology/advising/Forms.php

Corequisite: BIO 311 or BIO 365 forBiochemistry majors; an approved upper-division Biology course for Biology BS majors;an approved upper-division course in Biologyor in the minor degree program of BIO BAmajors; or departmental permission

SBC: WRTD


BIO 475: Undergraduate TeachingPracticum in College Biology I

Study of the literature, resources, and teachingstrategies in a field of biology, coordinatedwith a supervised clinical experience ininstruction. Not for major credit. Students maynot serve as teaching assistants in the samecourse twice.

Prerequisite: Permission of instructor; andUndergraduate Biology Program approval

SBC: EXP+


BIO 476: Undergraduate TeachingPracticum in College Biology II

Study of the literature, resources, and teachingstrategies in a field of biology, coordinatedwith a supervised clinical experience ininstruction. Not for major credit. Students maynot serve as teaching assistants in the samecourse twice.

Prerequisite: BIO 475; permission ofinstructor; Undergraduate Biology ProgramApproval

SBC: EXP+


BIO 484: Research in Biology andSociety

Students work under the supervision of afaculty member in developing an individualproject that makes use of the knowledge andtechniques acquired in previous courses. Thestudent reports on the project in a formatagreed upon with their faculty sponsor thatallows reflection on learning outcomes. Thiscourse may be repeated, but no more than fourcredits of research may be used for Biologymajor requirements. With prior permissionfrom the faculty sponsor, this course couldinclude assignments that can be used to satisfythe SBC objective SPK if co-registered forBIO 458, and/or the SBC objective WRTD ifco-registered for BIO 459.


SBC: EXP+


BIO 486: Research in Neurobiology andPhysiology

Students work under the supervision of afaculty member in developing an individualproject that makes use of the knowledge andtechniques acquired in previous courses. Thestudent reports on the project in a formatagreed upon with their faculty sponsor thatallows reflection on learning outcomes. Thiscourse may be repeated, but no more than fourcredits of research may be used for Biologymajor requirements. With prior permissionfrom the faculty sponsor, this course couldinclude assignments that can be used to satisfythe SBC objective SPK if co-registered forBIO 458 and/or the SBC objective WRTD ifco-registered for BIO 459.


SBC: EXP+


BIO 487: Research in Molecular,Cellular, and Developmental Biology

Students work under the supervision of afaculty member in developing an individualproject that makes use of the knowledge andtechniques acquired in previous courses. Thestudent reports on the project in a formatagreed upon with their faculty sponsor thatallows reflection on learning outcomes. Thiscourse may be repeated, but no more than fourcredits of research may be used for Biologymajor requirements. With prior permissionfrom the faculty sponsor, this course couldinclude assignments that can be used to satisfythe SBC objective SPK if co-registered for



BIO 458 and/or the SBC objective WRTD ifco-registered for BIO 459.


SBC: EXP+


BIO 488: Internship in BiologicalSciences

Students work under the supervision of afaculty member or approved professionalsponsor to obtain a career-related experiencein the life sciences. The student reports onthe project in a format agreed upon with theirsponsor that allows reflection on learningoutcomes. Students must be accepted intoan internship program before registering forcredit. May be repeated up to a limit of 12credits. Not for biology major credit.

Prerequisite: Undergraduate Biology Programapproval and permission of sponsor

SBC: EXP+


BIO 489: Research in Ecology andEvolution

Students work under the supervision of afaculty member in developing an individualproject that makes use of the knowledge andtechniques acquired in previous courses. Thestudent reports on the project in a formatagreed upon with their faculty sponsor thatallows reflection on learning outcomes. Thiscourse may be repeated, but no more than fourcredits of research may be used for Biologymajor requirements. With prior permissionfrom the faculty sponsor, this course couldinclude assignments that can be used to satisfythe SBC objective SPK if co-registered forBIO 458 and/or the SBC objective WRTD ifco-registered for BIO 459.


SBC: EXP+


CHEChemistry

CHE 115: Chemistry, Life, andEnvironment

This survey course introduces chemicalprinciples by emphasizing the role chemistryplays in everyday life, the natural environment,the built environment, energy production,and in processes leading to environmentaldegradation. In addition, the role of chemistryin the development of alternative energy

sources, remediation technologies, and eco-friendly products is discussed. This coursefor non-science majors introduces chemicalprinciples using mostly qualitative approachesrather than quantitative approaches. Interactivetools and interactive visualization toolsare extensively used to illustrate concepts,reactions, and processes. May not be taken bystudents with credit for CHE 129, CHE 131, orCHE 152. This course is offered as both CHE115 and ENV 115.

DEC: ESBC: SNW

3 credits

CHE 125: Learning Strategies Essentialfor Success in Chemistry

Focuses on developing techniques, strategies,and advanced learning skills that are essentialfor success in college-level chemistry. Realworld contexts, issues, and problems areexplored from a chemistry perspective.Provides a bridge from high school to collegecourses and from CHE 131 to CHE 132. Agrade of C or higher in CHE 125 satisfies theprerequisite for entry into CHE 132, providedCHE 129 or CHE 131 have been completedwith a passing grade (D or higher).

3 credits, ABC/U grading

CHE 129: General Chemistry IA

This is the initial course of the four-semesterGeneral-Chemistry/Organic-Chemistrysequence CHE 129/132/321/322. Thissequence provides the necessary foundationfor students who wish to pursue furthercoursework in chemistry. The GeneralChemistry Courses provide a broadintroduction to the fundamental principles ofchemistry, including substantial illustrativematerial drawn from the chemistry ofinorganic, organic, and biochemical systems.The emphasis is on basic concepts, problem-solving, and factual material. Studentswill be placed into CHE 129 based ontheir performance in the Online ChemistryPlacement and Preparation (OCPP) process.Specifically, CHE 129 is for students withchemistry knowledge above the requiredOCPP minimum but who do not meet themath corequisite of CHE 131. The level andcontent of CHE 129 match that of CHE 131,but since the corequisite differs, studentsmust also attend a CHE 130 session eachweek. CHE 130 builds essential skills ininformation processing, critical and analyticalthinking, quantitative reasoning, and problemsolving. The CHE 129 four-semester sequenceis inappropriate for students who satisfythe corequisites of CHE 131. It is alsoinappropriate for students who have completed

an AP course in chemistry and received ascore of 4 or 5; such students must enrollin CHE 152. Three lecture hours, one 80-minute workshop, and one CHE 130 sessionper week. CHE 129 may not be taken forcredit in addition to CHE 131 or CHE 152.This course has been designated as a HighDemand/Controlled Access (HD/CA) course.Students registering for HD/CA coursesfor the first time will have priority to do so.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: Online Chemistry Placement andPreparation (OCPP) Process. For informationon the OCPP, copy and paste the followinglink into your browser. go.stonybrook.edu/ocppMandatory co requisites: MAT 123 and CHE130

DEC: ESBC: SNW

4 credits

CHE 130: Problem Solving in GeneralChemistry

This course provides a structured environmentfor completing CHE 129 homeworkassignments and helping students developthe quantitative reasoning and problemsolving skills needed in General Chemistry.Satisfactory/Unsatifactory grading only.Grading is based on attendance andparticipation. Required for students takingCHE 129 along with MAT 123.

Mandatory corequisites: CHE 129 and MAT123


CHE 131: General Chemistry IB

This is the initial course in the four-semester General-Chemistry/Organic-Chemistry sequence CHE 131/132/321/322.This sequence provides the necessaryfoundation for students who wish to pursuefurther coursework in Chemistry. TheGeneral Chemistry courses provide a broadintroduction to the fundamental principles ofchemistry, including substantial illustrativematerial drawn from the chemistry ofinorganic, organic, and biochemical systems.The emphasis is on basic concepts, problem-solving, and factual material. The principaltopics covered are stoichiometry, the states ofmatter, chemical equilibrium and introductorythermodynamics, electrochemistry, chemicalkinetics, electron structure and chemicalbonding, and chemical periodicity. Studentswill be placed into CHE 131 based ontheir performance in an Online ChemistryPlacement and Preparation (OCPP) process.



The four-semester sequence is inappropriatefor students who have completed an APcourse in chemistry and received a score of4 or 5; these students are placed into CHE152. Three lecture hours and one 80-minuteworkshop per week. May not be taken forcredit in addition to CHE 129 or CHE 152.This course has been designated as a HighDemand/Controlled Access (HD/CA) course.Students registering for HD/CA coursesfor the first time will have priority to do so.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: Online Chemistry Placement andPreparation (OCPP) Process. For informationon the OCPP, copy and paste the followinglink into your browser. go.stonybrook.edu/ocpp Corequisite: MAT 125 or higher

DEC: ESBC: SNW

4 credits

CHE 132: General Chemistry II

A continuation of either CHE 129 or 131,introducing the fundamental principles ofchemistry, including substantial illustrativematerial drawn from the chemistry ofinorganic, organic, and biochemicalsystems. The principal topics covered arestoichiometry, the states of matter, chemicalequilibrium and introductory thermodynamics,electrochemistry, chemical kinetics, electronstructure and chemical bonding, and chemicalperiodicity. The sequence emphasizes basicconcepts, problem solving, and factualmaterial. It provides the necessary foundationfor students who wish to pursue furthercoursework in chemistry. Three lecture hoursand one 80-minute workshop per week. Maynot be taken for credit in addition to CHE 152.This course has been designated as a HighDemand/Controlled Access (HD/CA) course.Students registering for HD/CA coursesfor the first time will have priority to do so.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: C or higher in CHE 129 or CHE131. Pre/Corequisite: MAT 125 for those whotook CHE 129 or 130 or BA BIO majors; allothers MAT 126 or higher

DEC: ESBC: SNW

4 credits

CHE 133: General ChemistryLaboratory I

Designed to familiarize students with (1)some chemical and physical properties ofsubstances, (2) techniques of quantitative

chemistry, and (3) scientific methodology.Three hours of laboratory or related activityper week. CHE 133 and CHE 134 may notbe taken for credit in addition to CHE 154.This course has been designated as a HighDemand/Controlled Access (HD/CA) course.Students registering for HD/CA coursesfor the first time will have priority to do so.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Pre- or Corequisite: CHE 129 or 131

1 credit

CHE 134: General ChemistryLaboratory II

Designed to familiarize students with (1)some chemical and physical properties ofsubstances, (2) techniques of quantitativechemistry, and (3) scientific methodology.Three hours of laboratory or related activityper week. CHE 133 and CHE 134 may notbe taken for credit in addition to CHE 154.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisites: CHE 133Pre- or Corequisite: CHE 132

1 credit

CHE 152: Molecular Science I

This is the initial course of the three-semester Molecular Science sequenceCHE 152/331/332. The topics covered inCHE 152 include atomic and molecularstructure, chemical bonding, thermodynamics,equilibrium and aqueous chemistry,electrochemistry, kinetics and basics oforganic chemistry. Students will be placed intoCHE 152 based on their performance in theOnline Chemistry Placement and Preparation(OCPP) process or upon receipt of a score of4 or 5 in AP chemistry. (Such students cannotenroll in any of the courses CHE 129/130, 131,or 132). May not be taken for credit in additionto CHE 129, 131, or 132. Three lecture hoursand one 80-minute workshop per week.

Prerequisite: AP Chem score of 4-5 &satisfactory score on the Online ChemistryPlacement & Prep Process (OCPP) orsatisfactory score on the OCPP (http://go.stonybrook.edu/ocpp); co-registration inMAT 131 (preferred), MAT 125, AMS 151 orhigher calculus

DEC: ESBC: SNW

4 credits

CHE 154: Molecular Science LaboratoryI

Designed to familiarize students with chemicaland physical properties of substances,techniques of quantitative chemistry, andaspects of scientific methodology. Fourhours of lab per week. CHE 154 may notbe taken for credit in addition to CHE 134.This course has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Corequisite: CHE 152

2 credits

CHE 301: Physical Chemistry I

This course is the first half of a two-semesteroverview of modern physical chemistry,introducing students to the quantitative studyof chemical systems. The fundamentals ofthermodynamics from both macroscopic andmicroscopic standpoints are covered, withapplications to chemical problems. May notbe taken for credit by students who havecompleted CHE 312.

Prerequisite: CHE 132 or 152; MAT 132 or142 or 127 or 171 or AMS 161Pre/Co Requisite: MAT 203 or MAT 211or AMS 210 or AMS 261; PHY 121, 125,131/133, or 141

SBC: STEM+

4 credits

CHE 302: Physical Chemistry II

Introduction to quantum theory and itsapplication to the study of chemicalbonding, molecular spectroscopy, statisticalthermodynamics, chemical kinetics andmolecular reaction dynamics.

Prerequisites: CHE 301; MAT 203 or MAT211 or AMS 210 or AMS 261Pre- or Corequisite: PHY 122 or 132/134 or142 or PHY 126/127

4 credits

CHE 303: Solution ChemistryLaboratory

Quantitative techniques of solution chemistry.Measurement: accuracy and precision,analysis, computation, and reporting.Spectrophotometry. Solution equilibria andkinetics. Use of computers is introduced.Six hours of laboratory and discussion. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: CHE 134 or CHE 154Corequisite: CHE 301

SBC: ESI, WRTD

2 credits

CHE 304: Chemical InstrumentationLaboratory



Electrochemical and thermochemicalmeasurements. Electronics in chemicalinstrumentation. Vacuum techniques.Electrical and magnetic properties ofmaterials. Data-handling methods. Sixhours of laboratory and discussion. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: CHE 303. Corequisites: CHE302 and 385Advisory Prereq: Knowledge of computerprogramming

SBC: TECH, WRTD

2 credits

CHE 310: Chemistry in Technology andthe Environment

Use of chemical principles in understandingprocesses that occur in the moderntechnological world and in the naturalenvironment. Certain ecological problems ofa chemical nature are analyzed. Methods ofcontrolling these problems are discussed. Notfor credit in addition to ENV 320.

Prerequisite: CHE 132 or CHE 152

DEC: HSBC: STAS

3 credits

CHE 312: Physical Chemistry for theLife Sciences

A one-semester treatment of fundamentalconcepts of physical chemistry, intendedprimarily for students of the biologicalsciences desiring an introduction to physicalchemistry. Topics include equations of state;classical thermodynamics and its applicationto chemical equilibrium in reaction systems,multiphase systems, and electrochemical cells;kinetic theory of gases; transport properties;chemical kinetics. May not be taken for creditby students who have completed CHE 301.Not for major credit.

Prerequisite: #CHE 132 or 152; MAT 132 or142 or 127 or 171 or AMS 161Pre- or Corequisite: PHY 121 or 125 or131/133 or 141

SBC: STEM+

3 credits

CHE 321: Organic Chemistry I

An introduction to the structure, reactivity, andproperties of organic compounds is presentedusing modern views of chemical bonding.These fundamental ideas are applied to topicsranging from synthetic chemistry to complexfunctional structures such as lipid bilayers.This course has been designated as a HighDemand/Controlled Access (HD/CA) course.

Students registering for HD/CA courses for thefirst time will have priority to do so.

Prerequisite: C or higher in CHE 132

SBC: STEM+

4 credits

CHE 322: Organic Chemistry IIA

Discussion of the structure, reactivity, andproperties of organic compounds introducedin CHE 321 is continued. The chemistry ofsubstances important in biology, medicine,and technology is emphasized. CHE 322 maynot be taken for credit in addition to CHE 326.This course has been designated as a HighDemand/Controlled Access (HD/CA) course.Students registering for HD/CA courses for thefirst time will have priority to do so.


4 credits

CHE 326: Organic Chemistry IIB

Similar to CHE 322 but providing a morefundamental view of organic compounds,reaction mechanisms, and synthesis, basedsomewhat more explicitly on thermodynamicsand kinetics. Especially for those who maymajor in chemistry, biochemistry, or anotherphysical science. CHE 326 may not be takenfor credit in addition to CHE 322. This coursehas been designated as a High Demand/Controlled Access (HD/CA) course. Studentsregistering for HD/CA courses for the firsttime will have priority to do so.


4 credits

CHE 327: Organic ChemistryLaboratory

Techniques of isolating and handling organicsubstances, including biological materials.A one-semester course that provides abasic organic laboratory experience. Itis recommended that students take CHE327 at the same time as or immediatelyfollowing CHE 322 or 332. Four laboratoryhours and one lecture hour per week. Notfor credit in addition to CHE 383. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: CHE 134 or CHE 154Pre- or Corequisite: CHE 321 or CHE 331

2 credits

CHE 328: Synthetic and SpectroscopicLaboratory Techniques

Application of fundamental laboratorytechniques to organic and inorganic problemsincluding multistep syntheses and structuraland mechanistic determinations. Lectures

cover material pertaining to the experimentalwork, with an emphasis on spectroscopy.Not for credit in addition to CHE 384. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: CHE 327Pre- or corequisite: CHE 322

SBC: TECH

3 credits

CHE 331: Molecular Science II

Topics include the structural, mechanisticand synthetic aspects of organic chemistry,transition metal chemistry, catalysis,supramolecular chemistry, and polymerchemistry. This is the second course in athree semester sequence. Students witha strong background prior to enteringthe University can take the 152-331-332sequence, which covers the same material as131-132-321-322. Three lecture hours and one80-minute workshop per week. The laboratorycomponent, CHE 383, must be taken the samesemester as the CHE 331 lecture. May not betaken for credit in addition to CHE 321.

Prerequisite: C or higher in CHE 152Corequisite: CHE 383

SBC: STEM+

4 credits

CHE 332: Molecular Science III

Topics include advanced structural,mechanistic and synthetic aspects of organicchemistry, the organic chemistry of biologicalpathways and biosynthesis. This is the finalcourse in a three semester sequence. Studentswith a strong background prior to enteringthe University can take the 152-331-332sequence, which covers the same material as131-132-321-322. Three lecture hours and one80-minute workshop per week. May not betaken for credit in addition to CHE 322.


4 credits

CHE 341: Organic Chemistry HonorsSeminar I

Advanced topics in organic chemistry withinthe scope but beyond the reach of CHE 321(Organic Chemistry I) will be discussed alongwith an introduction to contemporary researchtopics. Permission to enroll will be granted tostudents who have demonstrated excellence intheir General Chemistry courses.

Prerequisites: CHE 132 or 142; permission ofinstructorCorequisite: CHE 321

SBC: ESI, SPK

1 credit



CHE 342: Organic Chemistry HonorsSeminar II

Advanced topics in organic chemistry withinthe scope but beyond the reach of CHE 322and CHE 326 (Organic Chemistry II) will bediscussed along with topics in contemporaryresearch. Permission to enroll will be grantedto students who have demonstrated excellencein CHE 321.

Prerequisites: CHE 321; permission ofinstructorCorequisite: CHE 322 or 326

SBC: ESI, SPK

1 credit

CHE 345: Structure and Reactivity inOrganic Chemistry

Electronic and stereochemical theories relatingto organic structure and reactions. Topics suchas bonding, strain, aromaticity, MO theory,molecular rearrangements, pericyclic reactions,and photochemistry are covered.

Prerequisite: CHE 322, CHE 326, or CHE 332Pre- or Corequisite: CHE 301 or 312

3 credits

CHE 346: Biomolecular Structure andReactivity

The reactivity and physiological functionof biological macromolecules and theirmonomeric constituents are described atthe chemical level. The course reflects themost recent advances at the interface oforganic chemistry and biochemistry. Specifictopics include catalysis, biomimicry, proteinand DNA modification, binding and targetrecognition, and correlation between three-dimensional structure and reactivity.

Pre- or Corequisites: CHE 322, CHE 326, orCHE 332; CHE 301 or CHE 312

3 credits

CHE 348: Reaction Mechanisms inOrganic Chemistry

Important classes of mechanisms of reactionsuseful in synthesis are explored. The kineticsand thermodynamics of these reactions areanalyzed using modern structural theories.Examples of reaction types are substitutions,rearrangements, additions, eliminations, andselected organometallic reactions.

Prerequisite: CHE 322, CHE 326, or CHE 332

3 credits

CHE 351: Quantum Chemistry

Concepts of quantum theory, Schrodingerwave mechanics, and related mathematicaltechniques illustrated by application to systemsof chemical bonding, spectroscopy, molecularstructure, and molecular collision phenomena.

Prerequisites: CHE 302; MAT 203 or 205

3 credits

CHE 353: Chemical Thermodynamics

A rigorous development of thermodynamicsand its application to systems of interest tochemists, including electrochemical cells,gases, polymers, and homogeneous andheterogeneous equilibrium. An introduction tostatistical mechanics is included.

Prerequisites: CHE 302; CHE 321

3 credits

CHE 357: Molecular Structure andSpectroscopy Laboratory

Optical and magnetic resonance spectroscopyare used to investigate the structural, dynamic,and quantum mechanical properties of somebasic chemical systems. Emphasis is onthe quantitative measurement of molecularparameters and transformations. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisites: CHE 304 and 383

2 credits

CHE 358: Computing in Chemistry

The basic elements of scripting, design ofcomputer programs, and numerical analysis arediscussed within the framework of solving avariety of exciting problems chosen from allareas of chemistry. Topics include automationof repetitive tasks, fitting of data, numericalintegration of rate equations, signal and imageanalysis, and quantum chemistry. No previousknowledge of computer programming isassumed.

Prerequisite: CHE 302 and CHE 304

3 credits

CHE 361: Nuclear Chemistry

Properties of radioactive substances and theiruse in the study of chemical problems, nuclearstability and structure, nuclear reactions,radioactive decay, interactions of radiationwith matter, nuclear medicine, isotopeapplications, and environmental control.Offered in summer only.

Prerequisites: Four semesters of chemistry;PHY 126 and 127, or 132/134 or 142 or171; AMS 161 or MAT 127 or 132 or 142;permission of department through applicationby January 30; permission of instructorCorequisite: CHE 362

3 credits

CHE 362: Nuclear ChemistryLaboratory

Detection and measurement of radiation,electronic instrumentation, radiation safety,and application of radioactivity to chemicalproblems. Offered in summer only.

Corequisite: CHE 361

3 credits

CHE 375: Inorganic Chemistry I

A survey of inorganic chemistry coveringvarious classes of inorganic compounds andreactions with emphasis on the structuralaspects. Wherever possible, the subject istreated on the basis of modern concepts ofchemical bonding. Thermodynamic and kineticaspects of inorganic reactions are included.

Prerequisite: CHE 322, CHE 326, or CHE 332

3 credits

CHE 376: Inorganic Chemistry II

The chemistry of the elements with anemphasis on the transition metals. Reactionmechanisms, synthesis, and structure arecovered. Specific areas of concern includecoordination chemistry, organometallicchemistry, bioinorganic chemistry, andselected topics from solid-state and non-transition metal chemistry.

Prerequisite: CHE 375

3 credits

CHE 378: Materials Chemistry

Our high-technology world is driven forwardby advances in materials chemistry. Thisclass will discuss some of the materials thatunderpin these technologies, as well as someof the novel classes of materials that arebeing developed for future applications. Thecourse will cover the synthesis, structures,and properties of advanced materials,focusing on a range of topics with currentsocietal importance (e.g. energy, computers,nanoscience, etc.). Specific topics mayinclude batteries, fuel cells, catalysts, metals,semiconductors, superconductors, magnetism,and polymers.

Prerequisite: CHE 375 or ESG 332

3 credits

CHE 383: Introductory Synthetic andSpectroscopic Laboratory Techniques

Fundamental laboratory techniques includingmethods of separation, purification, synthesis,and analysis. Emphasis is on organic withan introduction to inorganic problems. Forstudents in the Molecular Sciences sequence.Not for credit in addition to CHE 327. Threelecture hours and one 80-minute workshop perweek. The lecture component, CHE 331, mustbe taken the same semester as the CHE 383laboratory. This course has an associated fee.



Please see www.stonybrook.edu/coursefees formore information.

Prerequisite: CHE 154Corequisite: CHE 331

SBC: ESI

2 credits

CHE 384: Intermediate Synthetic andSpectroscopic Laboratory Techniques

Application of fundamental laboratorytechniques to organic and inorganic problemsincluding multistep syntheses and structuraland mechanistic determinations. Lecturescover material pertaining to the experimentalwork, with an emphasis on spectroscopy.Not for credit in addition to CHE 328. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisite: CHE 383Corequisite: CHE 332

SBC: TECH, WRTD

3 credits

CHE 385: Tools of Chemistry

A seminar course covering topics commonto all areas of chemistry: scientific ethics,chemical literature and information retrieval,scientific writing, and oral presentation. Athrough C/Unsatisfactory grading only.

Pre- or corequisite: CHE 327 or CHE 383

SBC: CER, SPK

1 credit, ABC/U grading

CHE 386: Professional Skills

Development and refinement of theprofessional skills used by scientists. Theexploration of more sophisticated presentationskills used in oral and poster presentations.The incorporation of collaborative problemsolving that mimics real world situations,including simple proposal writing. Anexposure to professional societies andmeetings. An exploration of career optionsand employment resources. Tips forresume preparation, and interviews will bepresented. Recommended for upper divisionundergraduates and Masters students.

Prerequisite: CHE 385 or permission ofinstructor

2 credits, S/U grading

CHE 444: Experiential Learning

This course is designed for students whoengage in a substantial, structured experientiallearning activity in conjunction with anotherclass. Experiential learning occurs whenknowledge acquired through formal learningand past experience are applied to a "real-

world" setting or problem to create newknowledge through a process of reflection,critical analysis, feedback and synthesis.Beyond-the-classroom experiences thatsupport experiential learning may include:service learning, mentored research, fieldwork, or an internship.


SBC: EXP+


CHE 459: Write Effectively in Chemistry

A zero credit course that may be taken inconjunction with any 300- or 400-level CHEcourse, with permission of the instructor. Thecourse provides opportunity to practice theskills and techniques of effective academicwriting and satisfies the learning outcomes ofthe Stony Brook Curriculum's WRTD learningobjective.

Prerequisite: WRT 102; permission of theinstructor

SBC: WRTD


CHE 461: Selected Topics in Chemistry

Semester supplements to this Bulletin containspecific description when course is offered.May be repeated as the topic changes.

Prerequisite: Varying with topic

1-3 credits

CHE 475: Undergraduate TeachingPracticum I

Work with a faculty member as an assistantin one of the faculty member's regularlyscheduled classes. The student is requiredto attend all the classes, do all the regularlyassigned work, and meet with the facultymember at regularly scheduled times to discussthe intellectual and pedagogical mattersrelating to the course. Students may participateonly in courses in which they have excelled.

Prerequisite: Permission of department

SBC: EXP+


CHE 476: Undergraduate TeachingPracticum II

Work with a faculty member as an assistantin one of the faculty member's regularlyscheduled classes. Students assume greaterresponsibility in such areas as leadingdiscussions and analyzing results of tests

that have already been graded. Students mayparticipate only in courses in which they haveexcelled. The course in which the student ispermitted to work as a teaching assistant mustbe different from the course in which he or shepreviously served.

Prerequisite: Permission of department

SBC: EXP+


CHE 477: Undergraduate TeachingPracticum III

Work with a faculty member as an assistantin one of the faculty member's regularlyscheduled classes. Students may participateonly in courses in which they have excelled.May be repeated.

Prerequisites: CHE 476; permission ofinstructor and department

SBC: EXP+


CHE 487: Research in Chemistry

Students pursue research or tutorial studyin specialized areas of chemistry. May berepeated.

Prerequisites: Permission of instructor anddepartment

SBC: EXP+

0-6 credits

CHE 488: Internship

Research participation in off-campuslaboratories. Students are required to submitto the department a proposal at the time ofregistration and a research report at the end ofthe semester. May be repeated up to a limit of12 credits.

Prerequisites: CHE 384; permission ofinstructor and department

SBC: EXP+


CHE 495: Senior Research

First course of a two-semester researchprogram to be carried out under thesupervision of a staff member. The results ofthis work are to be submitted to the departmentin the form of a senior research report. Thestudent is given an oral examination in Mayby a faculty committee consisting of thestudent's supervisor and three other facultymembers. Students receive only one gradeupon completion of the sequence CHE495-496.

Prerequisite: U4 standing; permission ofinstructor and department

SBC: EXP+



3 credits

CHE 496: Senior Research

Second course of a two-semester researchprogram to be carried out under thesupervision of a staff member. The results ofthis work are to be submitted to the departmentin the form of a senior research report. Thestudent is given an oral examination in Mayby a faculty committee consisting of thestudent's supervisor and three other facultymembers. Students receive only one gradeupon completion of the sequence CHE495-496.

Prerequisite: U4 standing; permission ofinstructor and department

SBC: ESI, EXP+, SPK

3 credits

BCPPharmacology

BCP 111: American Drug Use andAbuse: Biomedical, Socio-economicand Political Factors

This course, to be offered primarily online,introduces beginning students to the currentpharmacology landscape, both in the UnitedStates and abroad. New drug discovery andthe US drug approval process, for both over-the-counter and prescription pharmaceuticals,will be considered in detail and will becompared with comparable processes in otherparts of the world. The ethics of Americandirect-to-consumer marketing of prescriptionpharmaceuticals will be presented anddiscussed.

DEC: HSBC: STAS

3 credits

BCP 201: Introduction toPharmacology: Drug Use & ItsMolecular Basis

This course, to be offered primarilyface-to-face, introduces scientificallysophisticated students to all aspects of modernpharmacology including pharmacodynamics(how drugs elicit biological responses)and pharmacokinetics (drug absorption,distribution, metabolism, and excretion). Wewill discuss major classes of drugs commonlyused to treat illness in modern medical andveterinary practice. Agents considered willinclude those acting on the nervous system, theimmune system, the cardiovascular, respiratoryand gastrointestinal systems, and those usedin treating cancer and infectious diseases.

We will also consider vaccination to preventillness.

Prerequisite: BIO 202 and CHE 132Advisory Prerequisite: BCP 111

DEC: ESBC: STEM+

3 credits

BCP 400: Writing in Pharmacology

See requirements for the major inpharmacology, upper-division writingrequirement.

Prerequisites: Pharmacology major; U3 or U4standing; permission of instructor

SBC: WRTD


BCP 401: Principles of Pharmacology

Basic principles and mechanisms of drugdistribution, absorption, metabolism,and elimination. Principles of chemicalcarcinogenesis and tumor promotion.Autonomic, smooth-muscle, and CNSpharmacology. Pharmacology of specificdrugs of historical interest including alcohol,antibiotics, aspirin, nicotine, and morphine.Review of anticoagulants and thrombolyticagents, antiparasitics, and drugs for thetreatment of allergic conditions and gout.

Prerequisites: BIO 362; CHE 322 and 327; ag.p.a. of 3.00 or higher in these courses andtheir prerequisites.Corequisite for pharmacology majors: BCP403

4 credits

BCP 402: Advanced Pharmacology

Advanced concepts of drug metabolism,pharmacokinetics, biochemical, andmolecular mechanisms of drug action, anddrug resistance in human disease states.Toxicological agents and environmentalpollutants. The pharmacology of autocoids,anti-inflammatories, immunosuppressants, andantiasthmatics. Rational drug design and drugreceptor interactions using computer molecularmodeling techniques.

Prerequisites: BCP 401 and 403; minimum ofB- in BCP 401Corequisite: BCP 404

4 credits

BCP 403: Principles of PharmacologyLaboratory

The use of molecular modeling softwarefor the understanding of structure activityrelationships. In vivo studies to demonstratethe pharmacological mechanism of action ofdrugs acting on the autonomic, cardiovascular,and renal systems. Pharmacokinetic studies,

using HPLC, to determine the rate ofabsorption, distribution, and excretion oftherapeutic agents. Radio- and enzyme-immunoassays for the detection of circulatinghormones. Cell culture techniques for drugdetermination and evaluation.

Prerequisite: Permission of instructorCorequisite: BCP 401

SBC: ESI

2 credits

BCP 404: Advanced PharmacologyLaboratory

The use of molecular modeling softwarefor the understanding of structure activityrelationships. In vivo studies to demonstratethe pharmacological mechanism of action ofdrugs acting on the autonomic, cardiovascular,and renal systems. Pharmacokinetic studies,using HPLC, to determine the rate ofabsorption, distribution, and excretion oftherapeutic agents. Radio- and enzyme-immunoassays for the detection of circulatinghormones. Cell culture techniques fordrug determination and evaluation. Thiscourse has an associated fee. Please seewww.stonybrook.edu/coursefees for moreinformation.

Prerequisites: BCP 401 and 403; permissionof instructorCorequisite: BCP 402

SBC: ESI

2 credits

BCP 405: Pharmacology to Pharmacy:Practical Clinical Aspects for Non-Clinicians (Didactic)

This course, to be offered exclusively online,is designed for undergraduates interested inhealth care (either basic medical science-oriented or clinical). The class introducesmany aspects of clinical pharmacology, butis geared toward non-clinicians. Clinicalvignettes and case discussions will bepresented. Several medical procedures willbe first described and then demonstrated.Understanding these procedures will beintegral to appreciating the vignettes andclinical case discussions. The multidisciplinarycourse faculty will include physicians,scientists, educators, nurses and pharmacists.Enrolled students will have the opportunity toask questions directly through online chats.

Prerequisite: U3 or U4 status or permission ofthe instructor

SBC: ESI

3 credits

BCP 406: Pharmacology Colloquium



Seminars on research in pharmacologyand toxicology presented by faculty anddistinguished scientists from academic andindustrial institutions. Students are expectedto develop an understanding of the scientificprinciples presented in the colloquium.Speakers meet with the students after theseminar to discuss research concepts and toanswer questions. One hour Journal Club/Discussion followed by one hour seminar. Maybe repeated.

Prerequisites: BIO 202 and 203; CHE 322;a g.p.a. of 3.00 in these courses and theirprerequisites

SBC: SPK

2 credits

BCP 444: Experiential Learning

This course is designed for students whoengage in a substantial, structured experientiallearning activity in conjunction with anotherclass. Experiential learning occurs whenknowledge acquired through formal learningand past experience are applied to a "real-world" setting or problem to create newknowledge through a process of reflection,critical analysis, feedback and synthesis.Beyond-the-classroom experiences thatsupport experiential learning may include:service learning, mentored research, fieldwork, or an internship.


SBC: EXP+


BCP 475: Undergraduate TeachingPracticum in Pharmacology

Prerequisites: Pharmacology major; U4standing; permission of department

SBC: EXP+


BCP 480: Introduction to ResearchTopics in Pharmacology

Introduces undergraduate students to theresearch that is occurring in the laboratoriesof Pharmacology faculty. We will discussexperimental techniques and how they areutilized to investigate scientific questionswithin the various fields under the umbrellaof Pharmacological Sciences. Areas coveredwill include immunology, neuroscience,cancer, development, structural biology, cellsignaling, and stem cells. Students will berequired to prepare a presentation on research

actively occurring within the Pharmacologydepartment.

Prerequisite: BCP 201 or BCP 401 or BIO310 or BIO 361

SBC: TECH

1 credit

BCP 487: Research in Pharmacology

Completion of an individual student researchproject under the supervision of a facultymember. Previously acquired laboratory coursetechniques and new procedures are utilized.Experimental results must be submitted to thedepartment for grade evaluation in the formatof a research report. Not for credit in additionto HBH 396, 398, and 399. May be repeated.

Prerequisites: BIO 202 and 203; CHE 322 and327; a g.p.a. of 3.00 in these courses and theirprerequisites; permission of instructor anddepartment

SBC: EXP+

0-6 credits

BCP 488: Internship

Research participation in off-campuslaboratories, the pharmaceutical industry,and other academic and public agencies.Repeatable up to 12 credits.

Prerequisites: BIO 361; CHE 322; g.p.a.of 3.00 or higher in these courses and theirprerequisites; permission of department

SBC: EXP+


HBHPharmacology

HBH 398: Research Project inPharmacology

An independent research project under facultysupervision, with emphasis on the principlesof experimental design, data collection,evaluation of findings, and reporting of results.The student is expected to prepare a report onthe project. May be repeated. May not be takenfor credit in addition to BCP 487.

Prerequisite: Junior or Senior Standing

1-6 credits


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