DIAGNOSTICS-IMPACT ON THE PREMIUM CHANNEL – TearLab
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Transcript of DIAGNOSTICS-IMPACT ON THE PREMIUM CHANNEL – TearLab
Slide #2
LASIK & Cataract Surgery Technology Have Never Been Better
Slide #3
Ocular Surface is a Rate Limiting Step for Surgical Outcomes
The ocular surface affects:•IOL calculations•Topographic and wavefront ablations•Postoperative healing •Quality of vision and patient satisfaction
Slide #4
Sometimes it’s obvious. Sometimes it’s not.
Diagnosing the severe dry eye patient is easy.
The mild-moderate dry eye patient may look similar to normals
Slide #5
Using Diagnostics to ‘See’ Before We See
Kam W, et al. Invest Opthalmol Vis Sci. 2016; 57:E-abstract 6181.
Abnormal osmolarity can reveal a compromised ocular surface earlier
Slide #6
Effect of Hyperosmolarity on Keratometry Readings
Epitropoulos AT et al. J Cataract Refract Surg 2015 Aug;41(8)1672–7.
• 17% of hyperosmolar eyes had more than 1 D of change in keratometry cylinder values (Kcyl) between two visits
Slide #7
Future of Tear Biomarker Analysis
Osmolarity is important, but it’s not the only biomarker•Inflammatory markers•Allergic markers•DED subtyping markers
IL1-raIgE
Lactoferrin
Slide #8
Leading the Future of Diagnostics
TearLab Next Generation Platform•Quantitative•Rapid testing (< 2 minutes)•Multiplexed biomarkers•EHR Integration
Clinical Application•Normalization using osmolarity•Customized chips with designed sensitivity & specificity
Slide #9
• CE Mark by end of 2016• 510k submission in early 2017
– First test will have osmolarity + 1 or 2 additional markers– Likely to be focused on inflammation– New iterations possible every 6 months
When?