Veterinärmedizinische Universität Wien

Dermatologic cases for Riga

MVDr. Lucia Panakova, Dipl.ECVD

1

Lucky, Posavacki gonic, 2y,

castrated male

2

Lucky’s history

3

Referred to

dermatology for

allergic skin tests

On elimination diet

(Hypoallergenic RC)

for eight weeksno

improvement

poor compliance

suspected by the vet

Main complaint

Extremely severe

chewing feet

(pawpads and

nailbeds)

Also itchy on his

ventral abdomen

4

Rescued from Serbia

In the new family in

Austria since 4M

Found in a well

Treated with

Stronghold three

times no

improvement

After prednisolon

reduction of pruritus

by 50% for short

time 5

Lucky’s history

Lucky’s history

Any additional Qs?

6

Physical examination

No patological findings

7

Dermatologic examination

8

Hyperkeratotic, fissured pawpads on all digits,

erythematous interdigital pododermatitis, brown

discolored claws and some erythematous macules

and papules on the ventral chest and abdomen

9

Dermatologic examination

Problem lists

10

Problem lists

Severe pedal pruritus

Hyperkeratotic pawpads

Maculo-papular itchy rash on the abdomen

11

Differential diagnoses-pedal pruritus

12

Malassezia pododermatitis

Staphylococcal pododermatitis

Food induced allergic pododermatitis

Atopic dermatitis

Autumn mites (Neotrombicula autumnalis)

Pedal Demodicosis

Ancylostoma et uncinaria pododermatitis

13

Differential diagnoses-pedal pruritus

14

Differential diagnoses

pawpad hyperkeratosis

Differential diagnoses

pawpad hyperkeratosis

Keratinization problem due to metabolic

disease (Hepatocutaneous syndrome/ Zinc

responsive dermatoses)

Keratinization problem (primary/ genetic)

Keratinization problem by abnormal

environment

Orthopedic problem

Ancylostoma et uncinaria pododermatitis

Distemper

Pemphigus foliaceus

15

Differential diagnoses for

maculopapular rash

16

Differential diagnoses for

maculopapular rash

Pyoderma

Malassezia dermatitis

Scabies

Parasitic dermatitis (endoparasites)

Contact dermatitis

(Allergy)

17

Suggested approach

18

19

20

Skin scrapings

negative

21

Treatment

Cefalexine 20mg/kg BID

Malaseb every other day

22

11 days after the beginning of the

treatment- no improvement of the itch

23

What would you do now?

24

Parasitological fecal

flotation

Positive for eggs from

Ancylostoma/ Uncinaria

eggs

Ancylostoma et uncinaria

dermatitis

Treatment with fenbendazol

(Panacur®) pills

25

Four weeks later

26

27

7 weeks later

28

Ancylostoma et uncinaria

dermatitis

29

Ancylostoma et uncinaria dermatitis/

hookworm dermatitis

Rare parasitic disorder caused by L3 larvae from

the hookwoms- Ancylostoma or Uncinaria

Severe pruritus in the areas of larval migration

(pawpads and abdomen)

Dogs from poor hygienic conditions are diseased

Feces with worm eggs in the premises

transdermal migration of L3 larvae pruritus,

maculopapular rash and pedal hyperkeratosis

30

Approach to the dermatoses on the paws

31

History

Breed, age of onset, onset of clinical signs, lesions development

Clinical examination

Pawpads involvement Other skin

lesions Systemic signs

fever, hepatic,

Ocular, renal,

ophtalmic

hepatocutaneous sy,

PF, SEBD,

Leishmaniosis, VKH,

paraneoplastic,

vasulitis

Additional

diagnostic tests

Hematology,

Biochemistry,

Urinalysis, ANA…

Other

cutaneus

lesions

Vasculitis

Leishmaniasis

PF

CLE, SLE

Hepatocutane

ous

Allergies,

demodex

Pads

PF, Vasculitis

SEBD

Cong.Keratinization

Split pawpads

Hepatocutaneos

Zinc

resp.dermatosis

FB, endoparasites

Interdigital

space

Allergies,

Malassezia

and bacteria

FB

Demodicosis

Interdigital

cysts

endoparasites

Skin biopsies

Cytology,

scrapings, biopsy Cytology, serology,

scrapings, cultures,

biopsy

Bara, bordercollie, 2y, f

33

Cause of presentation

34

History

Skin disease for the last 2 months

Father of Bara euthanised because of

„devastationg skin disease“ few years ago

Therapy: (Amoxycillin- clavulanate)

Fluconazol syst. 2 t., different local antiseptics

Severe deterioration of the skin in the last two

weeks (june)

35

Clinical examination

T40,3°C

Other parameters- normal

36

Dermatologic

examination

37

38

39

40

Problem list

41

Problem list

Predominantly ventral symmetric ulcerative-

vesicular dermatitis

Confluent serpiginous areas of ulceration

ventrally

Ulceration and vesicles of buccal mucosa,

ulceration of anal mucucutaneous involvement

Fever

42

Differential diagnoses

43

Differential diagnoses

VCLE of shelties and collies

Pemphigus vulgaris

DE (drug eruption)

SEVBD (subepidermal vesiculobulous diseases)

Vasculitis

(Secondary pyoderma)

44

Suggested approach

45

46

47

48

Dermatohistopathology

Cell poor interface dermatitis with vaculolisation of

basal cells, multiple apoptoses and pigmentary

incontinence

51

Diagnosis

52

Diagnosis

VCLE

Superficial pyoderma

53

Therapy

54

Therapy

Ciclosporin A 5mg/kg SID

Prednisolon 2mg/kg/SID

Cefalexin 25mg/kg BID

Chlorhexidine Shampoo every day

55

56

57

58

59

60

Vesicular Cutaneous Lupus

Erythematosus in collies and shelties

Cutaneous ulcerative autoimmune disesae

with predominant ventral involvement

Collies and shelties

Originally mistaken for dermatomyositis

Middle old to old dogs

61

Vesicular Cutaneous Lupus

Erythematosus in collies and shelties

Serpiginous, ulcerative to confluent ulcerated

lesions of the ventral abdomen and inguinal

intertriginous skin

Vesicles of the oral buccal mucoses

Exacerbation in the summer months

62

ANA tests are negative

Secondary pyoderma

Potential life- threatening skin disease

Diagnosis: based on histopathology

Therapy: Combination of immunomodulatory and

immunosupressive drugs (glucocorticoids,

ciclosporin, and doxycyclin, tacrolimus/ topical/

63

Vesicular Cutaneous Lupus

Erythematosus in collies and shelties

Annual meeting ESVD-ECVD

Lausanne 7-9/09/2017

64

The ESVD jointly organizes an Annual Congress in conjunction

with

the European College of Veterinary Dermatology (ECVD) and

the LONG-TERM PARTNERS