Dendreon Title Page - Xconomy | Business, Life Sciences ... · geq!=ea>me;!eo!>hmi!i>j

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! "!

TABLE OF CONTENTS

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-:$2':(&1'2!&$;-<",!"-!4(+4'2+"+=/!!!../! .9>(2,$+,!-,$,'9'+,-!$+1!=<"1$+4'!:$?'!(),'+!! 4(+)&"4,'1!;",:!2'$&",@!(2!4:$+='1!-"=+")"4$+,&@!!

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"+4'+,"?"F'1G!!H"=+")"4$+,!"+-"1'2!-$&'-A!$+1!='+'2(<-!="),-!()!-,(4B!$+1!(>,"(+-!-'+1!,:'!;2(+=!9'--$='!,(!"+?'-,(2-/!

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Issue #1

THE LAWSUIT SETTLEMENT

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! "!

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! "!

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

! "!

#$%&'(!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)!*&+,-&$+!./0!12!3$+4&-&+5&!3677!8-6+'5-)9%:!!;<6)76=7&!6%!>>>:?$-+)+@'%6-:5$?:!))!A%%9(BB&+:>)C)9&,)6:$-@B>)C)BD$-?ED*;EFG2!)))A%%9(BB4)7&':'A6-&A$7,&-:5$?B,$>+7$6,'B*#*#B"HH"I2"JGK0KLGH/0M0NM*0J!!NM*/2GB//0J22MB4)7)+@:9,4!)<A%%9(BB4)7&':'A6-&A$7,&-:5$?B,$>+7$6,'B*#*#B"HH"I2"JGK0KL//0J22MNM*/0NM*FIB//0J22MB4)7)+@:9,4!

! "!

Issue #2

MANAGEMENT’S GUIDANCE

! "!

#$$%&!'(!

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! "#!

Issue #3

NONDISCLOSURE OF MATERIAL INFORMATION

! "#!

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! "#!

Issue #4

SIGNIFICANT INSIDER SELLING

! "#!

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$%!&'(')*&*($+,!-%&.*(,'$/%(!,$01-$10*!'(2!3/44!.1$!$%!0*,$!'(5!,6'0*6%42*0!,7*.$/-/,&!/(!$6'$!0*)'028!!9$!/,!'!3/(:3/(!;%0!*<*05%(*!$6'$!3/44!'44%3!$6*!-%&.'(5!$%!&%<*!;%03'02!3/$6!-%(;/2*(-*8!!=6*0*;%0*>!9!$6/(7!$6/,!$%./-!'22,!;10$6*0!-0*2*(-*!$%!&5!</*3!$6'$!?*(20*%(!3%142!@*!3*44!,*0<*2!@5!-%(,/2*0/()!'22/()!'!(*3!&*&@*0!%0!$3%!$%!/$,!@%'02!%;!2/0*-$%0,8!!

! "#!

$%&'()!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!*!+,,!%-!&.'!-*/01'(!*2!&.*(!3%405'2&!.67'!8''2!4%59*,'3!-1%5!:'231'%2;(!<=>!-*,*2/(?!!@.'A!61'!676*,68,'!6&!BBB?3'231'%2?4%5?!**!.&&9)CC*27'(&%1?3'231'%2?4%5C('4-*,*2/?4-5D-*,*2/E:F##GHIIJK#GK"LM>ENF##GHIIJ!

! "#!

Issue #5

PUBLIC RELATIONS CHALLENGES

! "#!

$%%&'!()!!

*+,+-'*',.!%''*%!&,/0'/+0'1!.2!'33'4.$5'67!0'42-,$8'!+,1!+,%9'0!.:'!4:+66',-'%!3+4$,-!.:'!42*/+,7!.:+.!+0'!2&.%$1'!23!.:'!%4$',.$3$4!0'+6*;!!

!!

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! ""!

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! "#!

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! "#!

http://www.denverpost.com/frontpage/ci_16182491

Costly cancer drugs raise tough questions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! "#!

SUMMARY OF RECOMMENDATIONS

! "#!

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