Dementia Current Awareness

Newsletter

February 2015

Contents Your Friendly Local Librarian… ........................................................................................................... 2

New Cochrane Library Systematic Reviews on Dementia ................................................................... 3

New from NICE .................................................................................................................................. 4

New from Department of Health ....................................................................................................... 4

New from Public Health England ....................................................................................................... 4

NHS Behind the Headlines ................................................................................................................. 5

Recent Literature Searches on Dementia ........................................................................................... 5

Current Awareness Database Articles on Dementia ........................................................................... 5

Dementia caring ............................................................................................................................ 5

Medical ....................................................................................................................................... 12

Therapies..................................................................................................................................... 18

Other ........................................................................................................................................... 20

Journal Tables of Contents............................................................................................................... 22

Alzheimer’s and Dementia ........................................................................................................... 22

Dementia: The International Journal of Social Research and Practice ........................................... 22

Age and Ageing ............................................................................................................................ 23

Journal of the American Geriatrics Society ................................................................................... 25

Your Friendly Local Librarian… Whatever your information needs, the library is here to help. As your outreach librarian I offer

literature searching services as well as training and guidance in searching the evidence and critical

appraisal – just email me at bennet.jones@uhbristol.nhs.uk

Outreach Your Outreach Librarian can help facilitate evidence-based practise for all in the dementia team, as

well as assisting with academic study and research. We can help with literature searching, obtaining

journal articles and books, and setting up individual current awareness alerts. We also offer one-to-

one or small group training in literature searching, accessing electronic journals, and critical

appraisal. Get in touch: bennet.jones@uhbristol.nhs.uk

Literature Searching We provide a literature searching service for any library member. For those embarking on their own

research it is advisable to book some time with one of the librarians for a 1 to 1 session where we

can guide you through the process of creating a well-focused literature research and introduce you

to the health databases access via NHS Evidence. Please email requests to

bennet.jones@uhbristol.nhs.uk

New Cochrane Library Systematic Reviews on

Dementia

Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies

Jenny McCleery, Shirlony Morgan, Kevin M Bradley, Anna H Noel-Storr,Olaf Ansorge, Chris Hyde

Published 30th Jan 2015

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010633.pub2/abstract

Dementia with Lewy bodies (DLB) is a common cause of neurodegenerative dementia of old age. Its

accurate recognition can be important in clinical management and is essential for the development

of disease-modifying treatments. The current clinical diagnostic criteria are limited particularly by

relatively poor sensitivity. Dopamine transporter (DAT) imaging using single-photon emission

computed tomography (SPECT) is the most highly developed supplementary test for DLB, and is now

incorporated as a suggestive feature in the consensus diagnostic criteria. However, there is

uncertainty about its accuracy and its place in clinical practice. It is most commonly used in people

who are already suspected of having DLB.

Objectives: We had two objectives in this review: (A) to estimate the accuracy of DAT imaging for

the diagnosis of DLB in people with dementia in secondary care (specialist dementia services), and

(B) to estimate the accuracy of DAT imaging for the diagnosis of DLB in people with dementia in

secondary care who are already suspected of having DLB on the basis of a prior clinical work-up.

18F-FDG PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people

with mild cognitive impairment (MCI)

Nadja Smailagic, Marco Vacant, Chris Hyde, Steven Martin, Obioha Ukoumunne, Christos

Sachpekidis

Published 28th Jan 2015

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010632.pub2/abstract

¹⁸F-FDFG uptake by brain tissue as measured by positron emission tomography (PET) is a well-

established method for assessment of brain function in people with dementia. Certain findings on

brain PET scans can potentially predict the decline of mild cognitive Impairment (MCI) to Alzheimer’s

disease dementia or other dementias.

Objectives: To determine the diagnostic accuracy of the ¹⁸F-FDG PET index test for detecting people

with MCI at baseline who would clinically convert to Alzheimer’s disease dementia or other forms of

dementia at follow-up.

Case management approaches to home support for people with dementia

Siobhan Reilly, Claudia Miranda-Castillo, Reem Malouf, Juanita Hoe, Sandeep Toot, David

Challis, Martin Orrell

Published 5th Jan 2015

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008345.pub2/abstract

Over 35 million people are estimated to be living with dementia in the world and the societal costs

are very high. Case management is a widely used and strongly promoted complex intervention for

organising and co-ordinating care at the level of the individual, with the aim of providing long-term

care for people with dementia in the community as an alternative to early admission to a care home

or hospital.

Objectives: To evaluate the effectiveness of case management approaches to home support for

people with dementia, from the perspective of the different people involved (patients, carers, and

staff) compared with other forms of treatment, including ‘treatment as usual’, standard community

treatment and other non-case management interventions.

New from NICE

Low-dose antipsychotics in people with dementia (NICE Advice)

New from Department of Health

Policy: Improving care for people with dementia

New from Public Health England

Press release: Recommendation against national dementia screening

NHS Behind the Headlines

Exposing the evidence behind the lurid newspaper headlines and how the media has

(mis)reported health news:

Media dementia scare over hay fever and sleep drugs

'Hibernation protein' could help repair dementia damage

Recent Literature Searches on Dementia

Below is a sample of literature searches carried out by librarians for UH Bristol members of staff

on the subject of Dementia. For further details get in touch: bennet.jones@uhbristol.nhs.uk

Dementia and “errorless learning”

Current Awareness Database Articles on

Dementia

Below is a selection of articles on dementia recently added to the healthcare databases, grouped

in the following categories:

Dementia caring

Medical

Therapies

Other

If you would like any of the following articles in full text, or if you would like a more focused

search on your own topic, then get in touch: bennet.jones@uhbristol.nhs.uk

Dementia caring

Title: Awareness of dementia by family carers of nursing home residents dying with dementia: A

post-death study.

Citation: Palliative Medicine, January 2015, vol./is. 29/1(38-47), 0269-2163;1477-030X (Jan 2015)

Author(s): Penders, Yolanda W. H, Albers, Gwenda, Deliens, Luc, Vander Stichele, Robert, Van den

Block, Lieve, EURO IMPACT

Abstract: Background: High-quality palliative care for people with dementia should be patient-

centered, family-focused, and include well-informed and shared decision-making, as affirmed in a

recent white paper on dementia from the European Association for Palliative Care. Aim: To describe

how often family carers of nursing home residents who died with dementia are aware that their

relative has dementia, and study resident, family carer, and care characteristics associated with

awareness. Design: Post-death study using random cluster sampling. Setting/participants: Structured

questionnaires were completed by family carers, nursing staff, and general practitioners of deceased

nursing home residents with dementia in Flanders, Belgium (2010). Results: Of 190 residents who

died with dementia, 53.2% of family carers responded. In 28% of cases, family carers indicated they

were unaware their relative had dementia. Awareness by family carers was related to more

advanced stages of dementia 1 month before death (odds ratio = 5.4), with 48% of family carers

being unaware when dementia was mild and 20% unaware when dementia was advanced. The

longer the onset of dementia after admission to a nursing home, the less likely family carers were

aware (odds ratio = 0.94). Conclusion: Family carers are often unaware that their relative has

dementia, that is, in one-fourth of cases of dementia and one-fifth of advanced dementia, posing

considerable challenges for optimal care provision and end-of-life decision-making. Considering that

family carers of residents who develop dementia later after admission to a nursing home are less

likely to be aware, there is room for improving communication strategies toward family carers of

nursing home residents. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal

abstract)

Title: The comparison of quality of life among people with mild dementia in nursing home and

home care-a preliminary report.

Citation: Dementia: The International Journal of Social Research and Practice, January 2015, vol./is.

14/1(114-125), 1471-3012;1741-2684 (Jan 2015)

Author(s): Nikmat, Azlina W, Hawthorne, Graeme, Al-Mashoor, Syed H

Abstract: Background: Living arrangements play an important role in determining the quality of life

(QoL) of people with dementia. Although informal care (home-based) is favored, the transition to

formal (institutional) care often becomes necessary, especially in the later stages of dementia.

Nevertheless, there is currently no definitive evidence showing that informal or formal care provides

a higher QoL for those with dementia. Objective: To compare the QoL of people with dementia in

the nursing home and home care, and identify factors that differentiate their QoL. Design and

methods: This was a cross-sectional survey. A total of 49 people with dementia >60 years old were

recruited from government nursing homes and hospitals (home care). Consenting participants were

assessed on cognitive severity, QoL, activities of daily living (ADLs), depression, and social

isolation/connectedness by the Short Mini Mental State Examination (SMMSE), the WHO-8 (the

EUROHIS-QOL), Short Assessment of Quality of Life (AQoL-8), Barthel Index (BI), Cornell Scale for

Depression (CSDD), and Friendship Scale (FS). Results: There were significant differences in QoL,

HRQoLs, ADLs, and social connectedness among people with dementia in home care (n = 19) and

those in nursing homes (n = 30) (p < 0.01). No significant differences were found by socio-

demographic factors, cognitive severity, or depression between the study cohorts. Conclusions Older

adults with dementia who were living at home experienced higher QoL, ADLs, and social

connectedness compared with those living in institutional care. Support should be provided enabling

home care and empowering caregivers to provide better care for people with dementia. (PsycINFO

Database Record (c) 2015 APA, all rights reserved) (journal abstract)

Title: Personality and dementia caring: A review and commentary.

Citation: Current Opinion in Psychiatry, January 2015, vol./is. 28/1(57-65), 0951-7367;1473-6578

(Jan 2015)

Author(s): Orgeta, Vasiliki, Leung, Phuong

Abstract: Purpose of review: Carers of people with dementia are at increased risk of experiencing

psychological distress. This article reviews recent findings on the role of personality traits for

psychological outcomes for carers of people with dementia. Recent findings: Several studies have

now established that personality influences the caregiving experience, carer wellbeing and outcomes

such as coping ability, burden and caregiving style. Several moderators of these associations have

also been identified such as the effect of kinship and type of dementia. There is consistent evidence

that carer personality characteristics influence the progression of the disease such as cognitive

decline and severity. Most of the recent studies identified in this review are cross-sectional.

Summary: Taken together, these results indicate that personality is an important psychological

resource for carers. Recent findings indicate that personality traits are associated with and influence

both carer and patient outcomes. Future research is necessary to guide interventions and to expand

further on our understanding of how personality factors shape adjustment to the caregiving role and

how these impact on the progression of the disease. (PsycINFO Database Record (c) 2015 APA, all

rights reserved) (journal abstract)

Title: Literature review: Use of respite by carers of people with dementia.

Citation: Health & Social Care in the Community, January 2015, vol./is. 23/1(51-63), 0966-

0410;1365-2524 (Jan 2015)

Author(s): Neville, Christine, Beattie, Elizabeth, Fielding, Elaine, MacAndrew, Margaret

Abstract: Respite care is a cornerstone service for the home management of people with dementia.

It is used by carers to mitigate the stress related to the demands of caring by allowing time for them

to rest and do things for themselves, thus maintaining the caring relationship at home and perhaps

forestalling long-term placement in a residential aged care facility. Despite numerous anecdotal

reports in support of respite care, its uptake by carers of people with dementia remains relatively

low. The aim of this paper was to examine the factors that constitute the use of respite by carers of

people with dementia by reviewing quantitative and qualitative research predominantly from the

years 1990 to 2012. Seventy-six international studies of different types of respite care were included

for this review and their methods were critically appraised. The key topics identified were in relation

to information access, the barriers to carers realising need for and seeking respite, satisfaction with

respite services including the outcomes for carers and people with dementia, the characteristics of

an effective respite service and the role of health workers in providing appropriate respite care.

Finally, limitations with considering the literature as a whole were highlighted and recommendations

made for future research. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal

abstract)

Title: Activities of daily living and quality of life across different stages of dementia: A UK study.

Citation: Aging & Mental Health, January 2015, vol./is. 19/1(63-71), 1360-7863;1364-6915 (Jan

2015)

Author(s): Giebel, Clarissa M, Sutcliffe, Caroline, Challis, David

Abstract: Objectives: People with dementia (PwD) require an increasing degree of assistance with

activities of daily living (ADLs), and dependency may negatively impact on their well-being. However,

it remains unclear which activities are impaired at each stage of dementia and to what extent this is

associated with variations in quality of life (QoL) across the different stages, which were the two

objectives of this study. Methods: The sample comprised 122 PwD, and their carers, either living at

home or recently admitted to long-term care. Measures of cognition and QoL were completed by

the PwD and proxy measures of psychopathology, depression, ADLs and QoL were recorded. Using

frequency, correlation and multiple regression analysis, data were analysed for the number of ADL

impairments across mild, moderate and severe dementia and for the factors impacting on QoL.

Results: ADL performance deteriorates differently for individual activities, with some ADLs showing

impairment in mild dementia, including dressing, whereas others only deteriorate later on, including

feeding. This decline may be seen in the degree to which carers perceive ADLs to explain the QoL of

the PwD, with more ADLs associated with QoL in severe dementia. Results of the regression analysis

showed that total ADL performance however was only impacting on QoL in moderate dementia.

Conclusion: Knowledge about performance deterioration in different ADLs has implications for

designing interventions to address specific activities at different stages of the disease. Furthermore,

findings suggest that different factors are important to consider when trying to improve or maintain

QoL at different stages. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal

abstract)

Title: Quality of life in dementia: A systematically conducted narrative review of dementia-specific

measurement scales.

Citation: Aging & Mental Health, January 2015, vol./is. 19/1(13-31), 1360-7863;1364-6915 (Jan

2015)

Author(s): Bowling, Ann, Rowe, Gene, Adams, Sue, Sands, Paula, Samsi, Kritika, Crane, Maureen,

Joly, Louise, Manthorpe, Jill

Abstract: Objectives: Ascertaining the quality of life (QoL) in people with dementia is important for

evaluating service outcomes and cost-effectiveness. This paper identifies QoL measures for people

with dementia and assesses their properties. Method: A systematic narrative review identified

articles using dementia QoL measures. Electronic databases searched were AMED, CINAHL, EMBASE,

Index to Theses, IBSS, MEDLINE, PsycINFO, Sociological Abstracts, and Web of Science. All available

years and languages (if with an English language abstract) were included. Results: Searches yielded

6806 citations; 3043 were multiple duplicates (759 being true duplicates). Abstracts were read; 182

full papers were selected/obtained, of which 126 were included as relevant. Few measures were

based on rigorous conceptual frameworks. Some referenced Lawton's model (Dementia Quality of

Life [DQOL] and Quality of Life in Alzheimer's Disease [QOL-AD]), though these tapped part of this

only; others claimed relationship to a health-related QoL concept (e.g. DEMQOL), though had less

social relevance; others were based on limited domains (e.g. activity, affect) or clinical opinions

(Quality of Life in Late-Stage Dementia [QUALID]). Many measures were based on proxy assessments

or observations of people with dementia's QoL, rather than their own ratings. The Bath Assessment

of Subjective Quality of Life in Dementia (BASQID) was developed involving people with dementia

and caregivers, but excluded some of their main themes. All measures were tested on selective

samples only (ranging from community to hospital clinics, or subsamples/waves of existing

population surveys), in a few sites. Their general applicability remains unknown, and predictive

validity remains largely untested. Conclusion: The lack of consensus on measuring QoL in dementia

suggests a need for a broader, more rigorously tested QoL measure. (PsycINFO Database Record (c)

2015 APA, all rights reserved) (journal abstract)

Title: Coming to grips with challenging behaviour: A cluster randomised controlled trial on the

effects of a new care programme for challenging behaviour on burnout, job satisfaction and job

demands of care staff on dementia special care units.

Citation: International Journal of Nursing Studies, January 2015, vol./is. 52/1(68-74), 0020-7489 (Jan

2015)

Author(s): Zwijsen, S. A, Gerritsen, D. L, Eefsting, J. A, Smalbrugge, M, Hertogh, C. M. P. M, Pot, A. M

Abstract: Background: Caring for people with dementia in dementia special care units is a

demanding job. Challenging behaviour is one of the factors influencing the job satisfaction and

burnout of care staff. A care programme for the challenging behaviour of nursing home residents

with dementia might, next to diminishing the challenging behaviour of residents, improve job

satisfaction and reduce the care staff's feelings of burnout. Objectives: To determine the effects of a

care programme for the challenging behaviour of nursing home residents with dementia on the

burnout, job satisfaction and job demands of care staff. Design: The care programme was

implemented according to a stepped wedge design in which care units were randomly divided over

five groups with different time points of starting with implementation. Setting: 17 Dutch dementia

special care units. Participants: Care staff members of the 17 units. Intervention: The care

programme consists of an education package and of various structured assessment tools that guide

professionals through the multidisciplinary detection, analysis, treatment and evaluation of

treatment of challenging behaviour. Methods: Burnout, job satisfaction and job demands were

measured before implementation, halfway through the implementation process and after all the

care units had implemented the care programme. Burnout was measured with the Dutch version of

the Maslach burnout inventory (UBOS-C, three subscales); job satisfaction and job demands were

measured with subscales of the Leiden Quality of Work Questionnaire. Mixed model analyses were

used to determine effects. Care staff could not be blinded for the intervention. Results: Of the 1441

questionnaires, 645 were returned (response 45%, 318 control measurements, 327 intervention

measurements) by 380 unique care staff members. Significant effects were found on job satisfaction

(0.93, 95% CI 0.48-1.38). On the other outcomes, no significant changes in the scores were found.

Conclusion: Positive effects of using the Grip on Challenging behaviour care programme were found

on job satisfaction, without an increase in job demands. (PsycINFO Database Record (c) 2015 APA, all

rights reserved) (journal abstract)

Title: Self and carer perspectives of quality of life in dementia using the QoL-AD.

Citation: International Journal of Geriatric Psychiatry, January 2015, vol./is. 30/1(97-104), 0885-

6230;1099-1166 (Jan 2015)

Author(s): Orgeta, Vasiliki, Orrell, Martin, Hounsome, Barry, Woods, Bob

Abstract: Objective: Quality of life (QoL) is one of the most important outcomes in improving well-

being in people with dementia (PwD). The primary aim of the present study was to compare self and

carer ratings of QoL in PwD and to identify the most important factors influencing self and carer

ratings. Methods: We conducted a cross-sectional analytic study of 488 dyads using the Quality of

Life in Alzheimer's Disease scale, demographics, data on self-rated health, and clinical

characteristics. Results: Higher levels of self-rated health in PwD were associated with higher self-

rated QoL after controlling for depression and activities of daily living. When the carer experienced

less stress related to caregiving, the PwD reported better QoL. Higher carer-rated QoL was

associated with less carer stress, better health for the family carer, and the PwD being of younger

age. When carers lived with the PwD, and reported lower levels of depression and better functional

ability for their relative, carer-rated QoL was higher. Conclusions: The self-rated health of PwD and

carers influences the ratings they make of the QoL of the PwD indicating that it is an important

influence on QoL in this population. (PsycINFO Database Record (c) 2015 APA, all rights reserved)

(journal abstract)

Title: Assisted dying in dementia: A systematic review of the international literature on the

attitudes of health professionals, patients, carers and the public, and the factors associated with

these.

Citation: International Journal of Geriatric Psychiatry, January 2015, vol./is. 30/1(10-20), 0885-

6230;1099-1166 (Jan 2015)

Author(s): Tomlinson, Emily, Stott, Joshua

Abstract: Background: Assisted death and dementia is a controversial topic that, in recent years, has

been subject to considerable clinical, ethical and political debate. Objective: This paper reviews the

international literature on attitudes towards assisted dying in dementia and considers the factors

associated with these. Design: A systematic literature search was conducted in Cumulative Index to

Nursing and Allied Health Literature, Excerpta Medica Database, PsychINFO and Web of Science

between 1992 and August 2013. Electronic and hand searches identified 118 potential relevant

studies. Eighteen studies met the full inclusion criteria and were screened using a quality assessment

tool. Results: Health professionals hold more restrictive views towards assisted dying, which appear

less affected by their cultural background, than the public, patients and carers. However, opinions

within each population vary according to dementia severity and issues of capacity, as well as

differing according to factors such as age, ethnicity, gender and religion of those surveyed. There

also appears to be a trend towards more accepting attitudes over time. Conclusions:

Sociodemographic factors can influence attitudes towards assisted dying. The impact of these,

however, may also differ according to the population surveyed. The findings from this review can

contribute to current debates and inform clinical practice and future research in this area. (PsycINFO

Database Record (c) 2015 APA, all rights reserved) (journal abstract)

Title: Help yourself: Perspectives on self-management from people with dementia and their

caregivers.

Citation: Qualitative Health Research, January 2015, vol./is. 25/1(87-98), 1049-7323;1552-7557 (Jan

2015)

Author(s): Toms, Gill R, Quinn, Catherine, Anderson, Daniel E, Clare, Linda

Abstract: Self-management interventions are increasingly offered to people with chronic health

conditions. However, there has been limited exploration of how applicable such an approach is in

early stage dementia. In this study we explored the views of people with dementia and family

caregivers on the use of self-management in dementia. We conducted semistructured interviews

with 13 people with early stage dementia and 11 caregivers. We analyzed transcripts using thematic

analysis. We found eight themes in the analysis, and they indicated that self-management occurs in

the context of peoples' family and social relationships as well as relationships with professional

services. Six of the themes involved barriers to and facilitators of self-management. It is evident from

these findings that people with dementia and caregivers use self-management techniques. Their use

of such techniques could be enhanced by the development of interventions designed to help people

with dementia to develop their self-management skills. (PsycINFO Database Record (c) 2014 APA, all

rights reserved) (journal abstract)

Title: A chronic grief intervention for dementia family caregivers in long-term care.

Citation: Western Journal of Nursing Research, January 2015, vol./is. 37/1(6-27), 0193-9459;1552-

8456 (Jan 2015)

Author(s): Paun, Olimpia, Farran, Carol J, Fogg, Louis, Loukissa, Dimitra, Thomas, Peggy E, Hoyem,

Ruby

Abstract: Dementia caregivers do not relinquish their role after placing family members in long-term

care and they experience increased chronic grief. The Chronic Grief Management Intervention

(CGMI) is a12-week group-based program that uses guided discussion to deliver knowledge of

Alzheimer's or a related dementia and teach skills in communication, conflict resolution, and chronic

grief management in dementia caregivers who placed their family members in long-term care. Using

a quasi-experimental design, 83 caregivers from 15 long-term care facilities received either the CGMI

(n = 34) or a comparison condition consisting of two check-in calls (n = 49). In this pilot study, we

examined the feasibility of implementing the CGMI and evaluated the effects of the intervention on

caregivers' knowledge and skill and their chronic grief and depression. The intervention was feasible

and resulted in significant improvement in caregivers' heartfelt sadness and longing at 3 months and

a significant drop in their guilt at the 6-month follow-up. (PsycINFO Database Record (c) 2014 APA,

all rights reserved) (journal abstract)

Medical

Title: Delirium and dementia with Lewy bodies: Distinct diagnoses or part of the same spectrum?

Citation: Journal of Neurology, Neurosurgery & Psychiatry, January 2015, vol./is. 86/1(50-59), 0022-

3050 (Jan 2015)

Author(s): Gore, Rachel L, Vardy, Emma R. L. C, O'Brien, John T

Abstract: Dementia with Lewy bodies (DLB) is recognised as the second most common form of

dementia in older people. Delirium is a condition of acute brain dysfunction for which a pre-existing

diagnosis of dementia is a risk factor. Conversely delirium is associated with an increased risk of

developing dementia. The reasons for this bidirectional relationship are not well understood. Our

aim was to review possible similarities in the clinical presentation and pathophysiology between

delirium and DLB, and explore possible links between these diagnoses. A systematic search using

Medline, Embase and Psychinfo was performed. References were scanned for relevant articles,

supplemented by articles identified from reference lists and those known to the authors. 94 articles

were selected for inclusion in the review. Delirium and DLB share a number of clinical similarities,

including global impairment of cognition, fluctuations in attention and perceptual abnormalities.

Delirium is a frequent presenting feature of DLB. In terms of pathophysiological mechanisms,

cholinergic dysfunction and genetics may provide a common link. Neuroimaging studies suggest a

brain vulnerability in delirium which may also occur in dementia. The basal ganglia, which play a key

role in DLB, have also been implicated in delirium. The role of Cerebrospinal fluid (CSF) and serum

biomarkers for both diagnoses is an interesting area although some results are conflicting and

further work in this area is needed. Delirium and DLB share a number of features and we

hypothesise that delirium may, in some cases, represent early or 'prodromal' DLB. Further research

is needed to test the novel hypothesis that delirium may be an early marker for future DLB, which

would aid early diagnosis of DLB and identify those at high risk. (PsycINFO Database Record (c) 2015

APA, all rights reserved) (journal abstract)

Title: Neuropsychiatric symptoms of dementia: Are pharmacological treatments effective and

safe?

Citation: Journal of Neurology, Neurosurgery & Psychiatry, January 2015, vol./is. 86/1(4), 0022-3050

(Jan 2015)

Author(s): Ford, Andrew H

Abstract: Comments on an article by Jun Wang et al. (see record 2014-56457-019). Wang et al.

systematically review available randomized clinical trials of pharmacological agents for the

treatment of neuropsychiatric symptoms in Alzheimer's dementia. This is the first attempt to

quantitatively analyze in one review paper the efficacy and tolerability of multiple medication

classes for these symptoms. The prevalence of neuropsychiatric symptoms associated with dementia

will inevitably increase as the population ages and clear evidence-based treatment is essential. This

review is a valuable and contemporary addition to this area of medicine and will hopefully help

guide clinical practice in this area. (PsycINFO Database Record (c) 2015 APA, all rights reserved)

Title: 'Rydym Eisiau Gwybod': The dementia diagnosis disclosure preferences of people in North

Wales.

Citation: International Journal of Geriatric Psychiatry, January 2015, vol./is. 30/1(108-110), 0885-

6230;1099-1166 (Jan 2015)

Author(s): Page, Sean, Davies-Abbott, Ian, Ingley, Sanjay, Bee, Penny

Abstract: Presents a study aims to reports a clinical audit regarding the preferences of 253 people

with dementia, attending Memory Assessment Services across North Wales, in relation to the

disclosure and sharing of their diagnoses. Twenty one participants (8.3%) preferred to receive their

diagnosis alone. Of those who did not want to be made aware of their diagnosis (n = 12, 4.8%), all

but one asked for their relative to be informed. Patients expressing a preference for non-disclosure

were 5.74 times more likely not to have their preferences actioned than those who requested

disclosure (95% CI 1.392 to 23.664). Female gender and a diagnosis of vascular or other type of

dementia marginally reduced the likelihood that patient preferences would not be actioned. People

from across North Wales who attend Memory Assessment services overwhelmingly want to know

the diagnosis that is made. We do not believe that our cohort are unique and see no reason why a

similar result would not be obtained in any Memory Service in the UK or beyond. These preferences

are important and disclosers need to be sufficiently experienced, confident and psychologically

prepared to not only say the words but to respond to the impact they have. (PsycINFO Database

Record (c) 2015 APA, all rights reserved)

Title: Medication management concerns of ethnic minority family caregivers of people living with

dementia.

Citation: Dementia: The International Journal of Social Research and Practice, January 2015, vol./is.

14/1(47-62), 1471-3012;1741-2684 (Jan 2015)

Author(s): Gillespie, Robyn J, Harrison, Lindsey, Mullan, Judy

Abstract: This qualitative study explored the medication management experiences of Australian

ethnic minority family caregivers of people living with dementia. From the perspective of this group

of caregivers, medication management was a source of stress resulting from the progressive loss of

ability of care recipients to manage their own medications; the complexity of the medication regime

and the caregiver's lack of trust of the care recipient to safely and effectively manage medications.

Caregivers used various strategies to manage medications and avoid conflict with care recipients

including being watchful and involving other family members in medication management tasks.

Family caregivers indicated that a lack of information and access to support to inform their

medication management role added to their stress, which was exacerbated in some cases by limited

English proficiency. Supportive factors noted by caregivers included a well-established relationship

with a community pharmacist, involvement of a geriatrician, family support and caregiver support

group participation. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract)

Title: Impairment of both languages in late bilinguals with dementia of the Alzheimer type.

Citation: Bilingualism: Language and Cognition, January 2015, vol./is. 18/1(90-100), 1366-7289;1469-

1841 (Jan 2015)

Author(s): Manchon, Melanie, Buetler, Karin, Colombo, Francoise, Spierer, Lucas, Assal, Frederic,

Annoni, Jean-Marie

Abstract: Neuropsychological theories raise the question if in late bilinguals with dementia of the

Alzheimer type (DAT), the second language (L2) may be more impaired than the first (L1). We

compared language performance in different tasks of oral comprehension (semantic and syntactic)

and production (naming, repetition and fluency) in L1 and L2 in a group of 13 late proficient

bilinguals wit DAT immersion, and a matched control group of 12 healthy late bilinguals. Two-way

mixed repeated-measure ANOVAs with factors Language and Group revealed main effects of Group

(p < .05) indicating that DAT affects all aspects of language. There was no Group x Language

interaction, suggesting that DAT affects both languages similarly. Our study thus shows that

neurodegenerative diseases affect L1 and L2 in a parallel manner, particularly at the levels of

semantic, lexical and syntactic processing. These results speak in favour of a shared L1 and L2

network in late bilinguals. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal

abstract)

Title: A systematic review and meta-analysis examining pneumonia-associated mortality in

dementia.

Citation: Dementia and Geriatric Cognitive Disorders, 2015, vol./is. 39/1-2(52-67), 1420-8008;1421-

9824 (2015)

Author(s): Foley, Norine C, Affoo, Rebecca H, Martin, Ruth E

Abstract: Background: Although it is generally accepted that deaths associated with pneumonia are

more common in patients with dementia, no comprehensive reviews on the subject have previously

been published. Summary: Relevant studies were identified through a literature search of the

PubMed, EMBASE, Scopus, and ISI Web of Science databases for publications up to August 2013.

Studies were included if (1) a group of adult subjects with dementia and a (comparison) group

composed of subjects without dementia were included, (2) the cause(s) of death was/were

reported, and (3) pneumonia was identified as one of the possible causes of death. The occurrence

of death due to pneumonia associated with dementia was expressed as an odds ratio (OR) with 95%

confidence interval (CI). Thirteen studies were included. The odds of death resulting from

pneumonia were significantly increased for persons with any form of dementia compared with those

without dementia (OR = 2.22, 95% CI 1.44-3.42, p < 0.001). In a subgroup analysis, using the results

from 8 studies that restricted inclusion to persons with Alzheimer's disease, the odds of death

resulting from pneumonia were also significantly higher (OR = 1.70, 95% CI 1.12-2.58, p = 0.013).

(PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract)

Title: The Mini-Addenbrooke's Cognitive Examination: A new assessment tool for dementia.

Citation: Dementia and Geriatric Cognitive Disorders, 2015, vol./is. 39/1-2(1-11), 1420-8008;1421-

9824 (2015)

Author(s): Hsieh, Sharpley, McGrory, Sarah, Leslie, Felicity, Dawson, Kate, Ahmed, Samrah, Butler,

Chris R, Rowe, James B, Mioshi, Eneida, Hodges, John R

Abstract: Background/Aims: We developed and validated the Mini-Addenbrooke's Cognitive

Examination (M-ACE) in dementia patients. Comparisons were also made with the Mini Mental State

Examination (MMSE). Method: The M-ACE was developed using Mokken scaling analysis in 117

dementia patients [behavioural variant frontotemporal dementia (bvFTD), n = 25; primary

progressive aphasia (PPA), n = 49; Alzheimer's disease (AD), n = 34; corticobasal syndrome (CBS), n =

9] and validated in an independent sample of 164 dementia patients (bvFTD, n = 23; PPA, n = 82; AD,

n = 38; CBS, n = 21) and 78 controls, who also completed the MMSE. Results: The M-ACE consists of

5 items with a maximum score of 30. Two cut-offs were identified: (1) < 25/30 has both high

sensitivity and specificity, and (2) < 21/30 is almost certainly a score to have come from a dementia

patient regardless of the clinical setting. The M-ACE is more sensitive than the MMSE and is less

likely to have ceiling effects. Conclusion: The MACE is a brief and sensitive cognitive screening tool

for dementia. Two cut-offs (25 or 21) are recommended. (PsycINFO Database Record (c) 2015 APA,

all rights reserved) (journal abstract)

Title: Memantine improves attention and episodic memory in Parkinson's disease dementia and

dementia with Lewy bodies.

Citation: International Journal of Geriatric Psychiatry, January 2015, vol./is. 30/1(46-54), 0885-

6230;1099-1166 (Jan 2015)

Author(s): Wesnes, Keith A, Aarsland, Dag, Ballard, Clive, Londos, Elisabet

Abstract: Objective: In both dementia with Lewy bodies (DLB) and Parkinson's disease dementia

(PDD), attentional dysfunction is a core clinical feature together with disrupted episodic memory.

This study evaluated the cognitive effects of memantine in DLB and PDD using automated tests of

attention and episodic memory. Methods: A randomised double-blind, placebo-controlled, 24-week

three centre trial of memantine (20 mg/day) was conducted in which tests of attention (simple and

choice reaction time) and word recognition (immediate and delayed) from the CDR System were

administered prior to dosing and again at 12 and 24 weeks. Although other results from this study

have been published, the data from the CDR System tests were not included and are presented here

for the first time. Results: Data were available for 51 patients (21 DLB and 30 PDD). In both

populations, memantine produced statistically significant medium to large effect sized

improvements to choice reaction time, immediate and delayed word recognition. Conclusions: These

are the first substantial improvements on cognitive tests of attention and episodic recognition

memory identified with memantine in either DLB or PDD. (PsycINFO Database Record (c) 2015 APA,

all rights reserved) (journal abstract)

Title: Genetics and underlying pathology of dementia.

Citation: Neuropsychology Review, January 2015(No Pagination Specified), 1040-7308;1573-6660

(Jan 8, 2015)

Author(s): Ferencz, Beata, Gerritsen, Lotte

Abstract: As the population steadily ages, dementia, in all its forms, remains a great societal

challenge. Yet, our knowledge of their etiology remains rather limited. To this end, genetic studies

can give us insight into the underlying mechanisms that lead to the development of dementia,

potentially facilitating treatments in the future. In this review we cover the most recent genetic risk

factors associated with the onset of the four most common dementia types today, including

Alzheimer's disease (AD), Vascular Dementia (VaD), Frontotemporal Lobar Degeneration (FTLD) and

Lewy Body Dementia (LBD). Moreover, we discuss the overlap in major underlying pathologies of

dementia derived from their genetic associations. While all four dementia types appear to involve

genes associated with tau-pathology and neuroinflammation only LBD, AD and VaD appear to

involve amyloid genes while LBD and FTLD share alpha synuclein genes. Together these findings

suggest that some of the dementias may exist along a spectrum and demonstrates the necessity to

conduct large-scale studies pinpointing the etiology of the dementias and potential gene and

environment interactions that may influence their development. (PsycINFO Database Record (c)

2015 APA, all rights reserved) (journal abstract)

Title: A systematic review of interventions to detect dementia or cognitive impairment.

Citation: International Journal of Geriatric Psychiatry, January 2015, vol./is. 30/1(32-45), 0885-

6230;1099-1166 (Jan 2015)

Author(s): Mukadam, Naaheed, Cooper, Claudia, Kherani, Nishin, Livingston, Gill

Abstract: Background: Memory services have been implemented nationally to increase early

dementia diagnosis, and further evaluation of their impact and other strategies to increase timely

dementia diagnosis are needed. Aims: To systematically review the literature for interventions

intended to increase the detection of dementia or suspected dementia or people presenting with

memory complaints. Method: We searched electronic databases, hand searched references and

contacted authors of included papers, contacted field experts and UK charities and councils for data

about their dementia awareness programmes. Results: We included 13 studies, of which four were

randomised controlled trials (RCT). Two RCTs found that general practitioner (GP) education

increased suspected dementia cases. One RCT found up to six home visits from a specialist geriatric

nurse over 30 months increased the rate of accurately diagnosed dementia. There was preliminary

evidence from non-randomised studies that memory clinics increase timely diagnosis, but no

evidence they increase the overall diagnosis rate. Conclusions: There is good quality evidence that

GP education increases the number of suspected dementia cases but not accurate or earlier

dementia diagnoses. One RCT reported that multiple visits from a trained nurse increase the

diagnosis rate. There is no cost effectiveness evidence. Our findings suggest good quality RCTs are

needed to test the effectiveness and cost-effectiveness of interventions to increase dementia

detection. (PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract)

Title: Translating cognitive and everyday activity deficits into cognitive interventions in mild

dementia and mild cognitive impairment.

Citation: International Journal of Geriatric Psychiatry, January 2015, vol./is. 30/1(21-31), 0885-

6230;1099-1166 (Jan 2015)

Author(s): Giebel, Clarissa, Challis, David

Abstract: Objective: Mild dementia is marked by deficits in cognition and everyday activities.

However, few studies have translated findings from both areas of functioning into effective cognitive

rehabilitation. The purpose of this review was to critically evaluate the existing literature on the type

and success of interventions and on their extent of use of cognitive theory. Given the limited

evidence base in this population, further insights were obtained from studies on mild cognitive

impairment (MCI), which involves fewer cognitive and everyday functioning problems than

dementia. Methods: From the literature searches, 11 studies on mild dementia and three studies on

MCI were obtained. Studies were only included if the interventions either targeted instrumental

activities of daily living or activities of daily living directly or as an outcome measure or if the

interventions focused on real-life aspects not captured in the standardised daily activities. For

inclusion, patients needed a diagnosis of dementia or MCI, and Mini-Mental State Examination

scores had to be above 17 for mild dementia. Results: The majority of interventions indicated

improved everyday activity performance in early dementia and MCI. Focusing on individual, as

opposed to global, daily activities appeared to be an important determinant of intervention success

in mild dementia but not in MCI. However, few attempts had been made to develop interventions

grounded in evidence-based models. Conclusions: This review highlights the need for further

translation of the understanding of cognitive and everyday activity deficits into successful

interventions for daily activities in MCI and early dementia. Hence, research is first required to link

individual activities with cognitive domains. (PsycINFO Database Record (c) 2015 APA, all rights

reserved) (journal abstract)

Therapies

Title: Creativity and dementia: Does artistic activity affect well-being beyond the art class?

Citation: Dementia: The International Journal of Social Research and Practice, January 2015, vol./is.

14/1(27-46), 1471-3012;1741-2684 (Jan 2015)

Author(s): Gross, Susan M, Danilova, Deana, Vandehey, Michael A, Diekhoff, George M

Abstract: The Alzheimer's Association's Memories in the Making (MIM) art activity program is

intended to enhance the well-being of individuals who are living with dementia. Previous evaluations

of MIM have found that participants show benefits on several well-being domains measured by the

Greater Cincinnati Chapter Well-Being Observation Tool. The current study extended those findings

by looking for evidence of carry-over effects beyond the temporal boundaries of MIM sessions.

Additionally, this study evaluated key psychometric qualities of the assessment instrument. Seventy-

six MIM participants with middle- to late-stage dementia were evaluated by interns and care facility

staff at the beginning, middle and end of a 12-week MIM program. Interns focused on behavior

within MIM sessions and staff rated functioning outside MIM sessions. Staff reported no significant

changes in resident well-being across the 12-week program. Interns reported significant

improvements from the beginning to middle and end of the program on five well-being domains.

Psychometric analyses of the Greater Cincinnati Chapter Well-Being Observation Tool identified

weaknesses in inter-rater reliability and found that the instrument measures two orthogonal factors-

interpreted as 'Well-Being' and 'Ill-Being'-not the seven domains claimed. Quantitative evidence for

the effectiveness of MIM is ambiguous, but anecdotal observations indicate that the program is

beneficial for some participants, if only fleetingly. (PsycINFO Database Record (c) 2015 APA, all rights

reserved) (journal abstract)

Title: A narrative analysis of poetry written from the words of people given a diagnosis of

dementia.

Citation: Dementia: The International Journal of Social Research and Practice, January 2015, vol./is.

14/1(9-26), 1471-3012;1741-2684 (Jan 2015)

Author(s): Clark-McGhee, Kitty, Castro, Maria

Abstract: This study is underpinned by social constructionist epistemology, which points to the

socially constructed character of our worlds, in that we co-create and are co-created by (including

experience and identity) our social realities. Through narrative analysis of some poems from the

words of people given a diagnosis of dementia, this study engaged in the process of meaning-making

in relation to Self-construct and the wider social world. Some narratives evidenced speakers' lack of

agency over their experiences, not because of the 'dementia' but due to treatment and care

contexts. Some narratives provided instances in which others positioned speakers into identity

constructions contradictory to their life-long Self-constructs. Other narratives demonstrated that,

through acknowledging and supporting 'personhood', speakers retained a sense of well-being and

purpose in their social worlds. It is hoped that focusing on the words of individuals given dementia

diagnoses, away from predominant bio-medical discourses, may facilitate professionals' continuous

reflection and person-centred practice. (PsycINFO Database Record (c) 2015 APA, all rights reserved)

(journal abstract)

Title: The effect of reminiscence therapy on depression, quality of life, ego-integrity, social

behavior function, and activies of daily living in elderly patients with mild dementia.

Citation: Educational Gerontology, January 2015, vol./is. 41/1(1-13), 0360-1277;1521-0472 (Jan

2015)

Author(s): Jo, HaeKyung, Song, Eunju

Abstract: This study investigated the effects of reminiscence therapy work on depression, quality of

life, ego-integrity, social behavior function, and activities of daily living. This study was a

quasiexperimental study using a single-group pretest/posttest design. This therapy consists of eight

sessions of 2.5 hours with a specific theme. A total of 19 patients with mild dementia who registered

at a mental health center in community-dwelling participated in this study. Hypotheses were

supported by quality of life, ego-integrity, and social behavior function. But depression and activities

of daily living were not supported. Although all the hypotheses were not supported, a reminiscence

therapy was beneficial. Patients with mild dementia can talk to each other naturally without feeling

a psychological burden, and they are provided the opportunity to look back on their life. (PsycINFO

Database Record (c) 2015 APA, all rights reserved) (journal abstract)

Title: Social support group interventions in people with dementia and mild cognitive impairment:

A systematic review of the literature.

Citation: International Journal of Geriatric Psychiatry, January 2015, vol./is. 30/1(1-9), 0885-

6230;1099-1166 (Jan 2015)

Author(s): Leung, Phuong, Orrell, Martin, Orgeta, Vasiliki

Abstract: Objectives: Despite the large number of studies evaluating social support groups for

people with dementia, there are no systematic reviews of current evidence. The aim of this study

was to evaluate the effectiveness of social support group interventions for people with dementia

and mild cognitive impairment. Methods: A systematic review was performed. We searched

electronic databases for randomised controlled trials. Two reviewers worked independently to select

trials, extract data and assess risk of bias. Results: A total of 546 studies were identified of which two

met the inclusion criteria. We were not able to pool data for further analyses, as the interventions

tested in the studies meeting the inclusion criteria were too dissimilar in content. The first trial (n =

136) showed a benefit of early-stage memory loss social support groups for depression and quality

of life in people with dementia. The second trial (n = 33) showed that post-treatment self-reported

self-esteem was higher in the group receiving a multicomponent intervention of social support

compared with that in the no intervention control group. Conclusions: Limited data from two studies

suggest that support groups may be of psychological benefit to people with dementia by reducing

depression and improving quality of life and self-esteem. These findings need to be viewed in light of

the small number, small sample size and heterogeneous characteristics of current trials, indicating

that it is difficult to draw any conclusions. More multicentre randomised controlled trials in social

support group interventions for people with dementia are needed. (PsycINFO Database Record (c)

2015 APA, all rights reserved) (journal abstract)

Other

Title: Learning to give voice in ministry to persons with dementia: Student monologues.

Citation: Journal of Religion, Spirituality & Aging, January 2015, vol./is. 27/1(34-47), 1552-

8030;1528-686X (Jan 2015)

Author(s): Harris, Helen Wilson, Scheibner, Alex

Abstract: As the population of older adults increases, the need for clergy and other professionals to

work with older adults increases as well. Students are often unfamiliar with the challenges faced by

persons with dementia and can benefit from opportunities to hear narratives that give voice to the

dementia experience. Monologues are an effective learning methodology to engage students and

ministers to prepare to work with older adults with dementia, sensitizing them to the struggles of

this challenging illness. This article includes rationale and a brief examination of practice literature

related to learning applications using monologue and guidelines for classroom application in

preparing students, ministers, and others for work with older adults with dementia. (PsycINFO

Database Record (c) 2015 APA, all rights reserved) (journal abstract)

Title: Comparison of general population, patient, and carer utility values for dementia health

states.

Citation: Medical Decision Making, January 2015, vol./is. 35/1(68-80), 0272-989X;1552-681X (Jan

2015)

Author(s): Rowen, Donna, Mulhern, Brendan, Banerjee, Sube, Tait, Rhian, Watchurst, Caroline,

Smith, Sarah C, Young, Tracey A, Knapp, Martin, Brazier, John E

Abstract: Utility values to estimate quality-adjusted life years (QALYs) for use in cost-utility analyses

are usually elicited from members of the general population. Public attitudes and understanding of

dementia in particular may mean that values elicited from the general population may differ from

patients and carers for dementia health states. This study examines how the population impacts

utility values elicited for dementia health states using interviewer-administered time tradeoff

valuation of health states defined by the dementia-specific preference-based measures DEMQOL-U

(patient-report) and DEMQOL-Proxy-U (carer-report). Eight DEMQOL-U states were valued by 78

members of the UK general population and 71 patients with dementia of mild severity. Eight

DEMQOL-Proxy-U states were valued by 77 members of the UK general population and 71 carers of

patients with dementia of mild severity. Random-effects generalized least squares regression

estimated the impact of population, dementia health state, and respondent sociodemographic

characteristics on elicited values, finding that values for dementia health states differed by

population and that the difference varied across dementia health states. Patients with dementia and

carers of patients with dementia gave systematically lower values than members of the general

population that were not due to differences in the sociodemographic characteristics of the

populations. Our results suggest that the population used to produce dementia health state values

could impact the results of cost-utility analyses and potentially affect resource allocation decisions;

yet, currently, only general population values are available for usage. (PsycINFO Database Record (c)

2015 APA, all rights reserved) (journal abstract)

Journal Tables of Contents

The most recent issues of the following journals:

Alzheimer’s and Dementia

Dementia: The International Journal of Social Research and Practice

Age and Ageing

Journal of the American Geriatrics Society

Click on the links for abstracts. If you would like any of these papers in full text then get in touch:

bennet.jones@uhbristol.nhs.uk

Alzheimer’s and Dementia

Vol. 11, iss.1, January 2015 The Centiloid Project: Standardizing quantitative amyloid plaque estimation by PET Risk factors for incident dementia after stroke and transient ischemic attack Adverse events and dropouts in Alzheimer's disease studies: What can we learn? Brain tocopherols related to Alzheimer's disease neuropathology in humans Resolution of inflammation is altered in Alzheimer's disease Potential role of antimicrobial peptides in the early onset of Alzheimer's disease Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease At the interface of sensory and motor dysfunctions and Alzheimer's disease A new way to produce hyperketonemia: Use of ketone ester in a case of Alzheimer's disease Alzheimers Association Update

Dementia: The International Journal of Social Research and Practice

Vol. 14, iss. 1, January 2015

Dementia and Prescribed Disengagement™;

Editorial note

A narrative analysis of poetry written from the words of people given a diagnosis of dementia

Creativity and dementia: Does artistic activity affect well-being beyond the art class?

Medication management concerns of ethnic minority family caregivers of people living with

dementia

Caregivers' willingness-to-pay for Alzheimer's disease medications in Canada

A technology roadmap of assistive technologies for dementia care in Japan

From evidence to practice: Using the RE-AIM framework to adapt the REACHII caregiver

intervention to the community

The comparison of quality of life among people with mild dementia in nursing home and home

care--a preliminary report

Changes in daily cognition and behavior of Alzheimer's patients over time: A three-year evaluation

using a daily cognition and behavior for Alzheimer's disease scale

Book review: Editorial

Karen Watchman (ed.), Intellectual disability and dementia research into practice

Amanda Alders Pike, Improving memory through creativity

Susannah Howard and Julia Miranda (eds), The things between us. Living words: anthology 1

Age and Ageing

Vol.44, iss. 1, January 2015

Editor's view

Bournewood revisited--do recent changes to the law regarding Deprivation of Liberty Safeguards

represent an opportunity or an opportunity cost?

Is blood leptin a biomarker for dementia development?

Death: a foe to be conquered? Questioning the paradigm

The contribution of geriatric medicine to integrated care for older people

Physical therapies for improving balance and reducing falls risk in osteoarthritis of the knee: a

systematic review

Systematic review of recent dementia practice guidelines

Assessment and management of fracture risk in patients with Parkinson's disease

A prospective observational study to investigate the association between abnormal hand

movements and delirium in hospitalised older people

Much more medicine for the oldest old: trends in UK electronic clinical records

Plasma leptin levels are not predictive of dementia in patients with mild cognitive impairment

Cognitive consequences of overweight and obesity in the ninth decade of life?

Glycaemia is associated with cognitive impairment in older adults: the Guangzhou Biobank Cohort

Study

How does additional diagnostic testing influence the initial diagnosis in patients with cognitive

complaints in a memory clinic setting?

Dementia prediction for people with stroke in populations: is mild cognitive impairment a useful

concept?

Alcohol consumption and physical functioning among middle-aged and older adults in Central and

Eastern Europe: Results from the HAPIEE study

Polypharmacy including falls risk-increasing medications and subsequent falls in community-

dwelling middle-aged and older adults

Association of vegetables and fruits consumption with sarcopenia in older adults: the Fourth

Korea National Health and Nutrition Examination Survey

Under-reporting of food intake and body fatness in independent older people: a doubly labelled

water study

Reactive stepping behaviour in response to forward loss of balance predicts future falls in

community-dwelling older adults

Effects of vertical and side-alternating vibration training on fall risk factors and bone turnover in

older people at risk of falls

Is socioeconomic status a predictor of mortality in nonagenarians? The vitality 90+ study

No relation between CMV infection and mortality in the oldest old: results from the Belfrail study

Non-linear associations between serum 25-OH vitamin D and indices of arterial stiffness and

arteriosclerosis in an older population

Economic evaluation of the differential benefits of home visits with telephone calls and telephone

calls only in transitional discharge support

Diagnostic test accuracy of simple instruments for identifying frailty in community-dwelling older

people: a systematic review

Association of gait speed with mortality among the Japanese elderly in the New Integrated

Suburban Seniority Investigation Project: a prospective cohort study

Safety of intravenous thrombolysis for ischaemic stroke in Asian octogenarians and nonagenarians

Prevalence of frailty and disability: findings from the English Longitudinal Study of Ageing

Towards an understanding of why undergraduate teaching about delirium does not guarantee

gold-standard practice--results from a UK national survey

A case of painless acute Type-A thoracic aortic dissection

FDG-PET in a myocardial tuberculoma

Corrigendum to 'Validation of the 4AT, a new instrument for rapid delirium screening: a study in

234 hospitalised older people'

Journal of the American Geriatrics Society

Vol. 63, iss. 1, January 2015 A Prospective Study of the Use and Effects of Screening Mammography in Women Aged 70 and Older (pages 1–7) Depressive Symptoms, Cardiovascular Disease Severity, and Functional Status in Older Adults with Coronary Heart Disease: The Heart and Soul Study (pages 8–15) Impaired Olfaction and Risk of Delirium or Cognitive Decline After Cardiac Surgery(pages 16–23) Factors that Affect Quality of Life from the Perspective of People with Dementia: A Metasynthesis (pages 24–38) Predictors of Admission After Emergency Department Discharge in Older Adults(pages 39–45) Visual Impairment and Incident Mobility Limitations: The Health, Aging and Body Composition Study (pages 46–54) Hospital-Associated Functional Decline: The Role of Hospitalization Processes Beyond Individual Risk Factors (pages 55–62) Effect of a Falls Quality Improvement Program on Serious Fall-Related Injuries(pages 63–70) Underuse of Oral Anticoagulation for Individuals with Atrial Fibrillation in a Nursing Home Setting in France: Comparisons of Resident Characteristics and Physician Attitude (pages 71–76) Epidemiology of Drug–Disease Interactions in Older Veteran Nursing Home Residents (pages 77–84) Comparison of Anticholinergic Risk Scales and Associations with Adverse Health Outcomes in Older People (pages 85–90) Tooth Loss Associated with Physical and Cognitive Decline in Older Adults (pages 91–99) Associations Between Oral Health and Risk of Dementia in a 37-Year Follow-Up Study: The Prospective Population Study of Women in Gothenburg (pages 100–105)

Frailty Prevalence and Neighborhood Residence in Older Mexican Americans: The San Antonio Longitudinal Study of Aging (pages 106–111) Lower Blood Pressure and Apathy Coincide in Older Persons with Poorer Functional Ability: The Discontinuation of Antihypertensive Treatment in Elderly People (DANTE) Study Leiden (pages 112–117) Self-Reported Walking Difficulty Predicts Late-Life Mortality in Finnish War Veterans: Results from the Veteran 1992 Project Survey (pages 118–123) Statin Use and Decline in Gait Speed in Community-Dwelling Older Adults (pages 124–129) The Pittsburgh Fatigability Scale for Older Adults: Development and Validation(pages 130–135) Comparative Study of Four Physical Performance Measures as Predictors of Death, Incident Disability, and Falls in Unselected Older Persons: The Insufficienza Cardiaca negli Anziani Residenti a Dicomano Study (pages 136–141) American Geriatrics Society Abstracted Clinical Practice Guideline for Postoperative Delirium in Older Adults (pages 142–150) Significant Unmet Oral Health Needs of Homebound Elderly Adults (pages 151–157) High Rates of Native Hawaiian and Older Japanese Adults Hospitalized with Dementia in Hawai‘i (pages 158–164) The Optimizing Patient Transfers, Impacting Medical Quality, and Improving Symptoms: Transforming Institutional Care Approach: Preliminary Data from the Implementation of a Centers for Medicare and Medicaid Services Nursing Facility Demonstration Project (pages 165–169) Mammography Screening for Women Aged 70 and Older: At a Crossroads (pages 170–172) Coordinated Care of Medically Complex Individuals in an Individual-Centered Medical Home: The Surprising Case of Mr. and Mrs. W (pages 173–174) Cinderella's Lifetime Abuse (page 175) Effects of Tai Chi Ball on Balance and Physical Function in Older Adults with Type 2 Diabetes Mellitus (pages 176–177) Physical Fitness and Sociocognitive Engagement are Associated with Different Aspects of Cognition in Older Adults (pages 177–179) Proton Pump Inhibitors and Hypomagnesemia in Polymorbid Elderly Adults (pages 179–180) Insight Into Elder Abuse Among Urban Poor of Kuala Lumpur, Malaysia—A Middle-Income Developing Country (pages 180–182) Lower Glomerular Filtration Rate Associated with White Matter Hyperintensities More in Vascular Dementia Than in Alzheimer's Disease (pages 182–183)

Cessation of Driving is Rare in Older Drivers Seen in the Emergency Department After a Motor Vehicle Collision: A Prospective Cohort Study (pages 183–185) Association Between Potentially Inappropriate Medication Use in Elderly Adults and Hospital-Related Outcomes (pages 185–186) Development of an Age-Dependent Antibiogram in a Veterans Affairs Community(pages 186–188) Cutaneous Surgery Complications in Individuals Aged 80 and Older Versus Younger Than 80 After Excision of Nonmelanoma Skin Cancer (pages 188–190) Effect of Early Diagnosis and Lifestyle Modification on Functional Activities in Community-Dwelling Elderly Adults with Glucose Intolerance: 5-Year Longitudinal Study (pages 190–192) High Prevalence of Undiagnosed Eye Diseases in Individuals with Dementia (pages 192–194) Online Administration of a Quantified Self-Questionnaire for Elderly People: A User Satisfaction Survey (pages 194–195) The Need for Uniform Quality Reporting Across Post-Acute Care Rehabilitation Settings: An Examination of Accidental Falls (pages 195–197) Persistent Dizziness (pages 197–198) Sarcoidosis Presenting As Late-Onset Dementia: Are Cerebrospinal Fluid Biomarkers Analyses Helpful? (pages 198–200) Response to Thomas E. Finucane, MD (pages 203–204) Learning From Experience and Making Plans? (page 204) Televideo Clock Drawing Test to Reach Rural Veterans: Feasibility in Community-Based Outpatient Clinics in the Department of Veterans Affairs (pages 205–206) Testosterone Levels and Bone Mineral Density in Healthy Elderly Men (pages 206–207) Establishing Code Status: Are People's Decisions Truly Informed? (pages 207–208) Morley-JAGS Link to Perspectives of Geriatrics Paper (page 208) Erratum (page 209) Notices (page 210)

Library Opening Times

Staffed hours: 8am-5pm, Mon-Fri

Swipe-card access: 7am-11pm 7 days a week

Level 5, Education and Research Centre

University Hospitals Bristol

Contact your outreach librarian:

Bennet Jones, outreach librarian

bennet.jones@uhbristol.nhs.uk

Ext. 20103