Cyberinfrastructure for CHOIS a Global Health initiative for obesity surveillance and control

National University Community Research Institute (NUCRI)

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Cyberinfrastructure for CHOIS a Global Health initiative

for obesity surveillance and control

Arun K. Datta1, Victoria Jackson2, Radha Nandkumar3, and Weimo Zhu4

1National University2Illinois Department of Human Services3National Center for Supercomputing Applications4University of Illinois at Urbana-Champaign


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NU Community Research Institute (NUCRI)

• National School Board (NCC/FRC)

• HASTAC (higher education)/HASS grid

• UC Humanities Research Institute

• K12 (AmeriCorps)• ARTCA• Illinois Department of Public

Health• NCSA/University of Illinois at

Urbana-Champaign• SmileHealthy, SIU, SALTRA, etc.focused on digital technology need based

Research for the community

NUCRI is an outreach to the Community for National University

(http://nucri.nu.edu)


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NU Community Research Institute (NUCRI)

(http://nucri.nu.edu)

i-Dataware – web based integrated database system for providing social services

ezSRB – web based interface for managing data through Storage Resource Broker (SRB) middleware; used in HASSgrid deployment

VCMSS – virtual collaboratory tool for working on collaborative projects

FastApps – web based software system for grant management

CyberEdWorld – immersive 3D space for virtual classroom

Open source software technologies (Portal Technology, Content management Software/Drupal, audio/video communication software/Access Grid, PHP, MySQL…)

Tools and Technologies


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https://ncc.nu.edu/


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CHOIS

Electronic Medical Record System

Supported by CI

Childhood Obesity Informatics System


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Electronic Medical Record

By 2014, all the citizens should have an access to his/her Electronic Medical Record.

Communications of the ACM, Nov 2009, Vol 52 (11), 18-20.

EMR are widespread in Europe, Australia, and elsewhere, but only 4% of American doctors have a fully functional system.

New England J. med., 356, 24, June 14, 2007, 2527 – 34.


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Information flow commonly present


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Implementing Electronic Medical Record

• Benefits are obvious• Reduction of clerical errors • Clinical-decision support• Furthering medical research

• Economic Incentives to doctors• Economic Incentives to Hospitals

• Regulations – HIPAA, FERPA• Standards (HL 7, ISO, DICOM, etc.)• Data Integration• Data exchange

Communications of the ACM, Nov 2009, Vol 52 (11), 18-20.


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Data Integration

CT finding, Epithelial carcinoma of the ovary

X-ray

HematologyElectronic Medical Record Electronic Healthcare RecordOral Pathology HistopathologyBlood tests

Image of acute arterial embolism

Microarray

Scanning Tunneling Microscopy

Transmission electron microscopy

Atomic force microscope (AFM)

Heart surgery

http://en.wikipedia.org/wiki/Image:Microarray2.gif

http://upload.wikimedia.org/wikipedia/en/e/e9/TEM.jpg

http://www.newmediamedicine.com/videos/

http://mybaby4d.com/4dultrasoundvideos.html

http://www.youtube.com/watch?v=hc0DtR-qW7E


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Echocardiography (EKG)

Tablet-PC

Smart Phone

Electronic Devices for capturing the data


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• EHR will be in place by 2014

• Health information exchange policy will be in place

• Medical devices will be standardized to send the data to the EHR and ‘connect’ to each other

• Patient will have a greater control over his/her health data

• Patients will have more control over surveillance system

• More meaningful reports can be generated using CI

• Users needs to be trained for appropriate use of EHR

CI in Healthcare Management


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Obesity – a Global Concern

U.S. National Health and Nutrition Examination Survey suggests almost 1/3 of children and adolescents are overweight or obese and 11.3% of children and adolescents are very obese.

Since last two decades, it has become so common that in 1997 the World Health Organization (WHO) formally recognized it as a global epidemic.


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The economic impact of this condition is staggering: in 2008, it has been estimated that more than 147 billion dollars were spent just in the United States for medical costs related to obesity and this estimation does not include the time lost from work. If this trend continues, it has been projected that nearly one-fifth of the healthcare budget in US alone may have to be used for obesity control [1,2]. Due to all these, obesity has become a major concern in US.

The present administration under President Obama has recently established a task force on childhood obesity (White house, February 09, 2010).

1. Wang Y, Beydoun MA, Liang L, Caballero B, Kumanyika SK. Obesity, 16 (2008), 2323-30

2. Hammond RA. Prev Chronic Dis. 6 (2009). Retrieved on February 14, 2010 from http://www.cdc.gov/pcd/issues/2009/jul/09_0017.htm.


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A 2006 review identified ten possible contributors to the recent increase of obesity [1]. Obesity is the result of interplay between genetic and environmental factors. Polymorphisms in various genes controlling appetite and metabolism predispose to obesity when sufficient calories are present. As of 2006, more than 41 of these sites have been linked to the development of obesity when a favorable environment is present [2].

A sedentary lifestyle obviously plays a significant role in obesity.

1. Keith, T. Genetic Engineering and Biotechnology News, 27 (2), Jan 15 20072. Poirier P, Giles TD, Bray GA, et al. Arterioscler. Thromb. Vasc. Biol. 26 (2006), 968–76.


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http://nucri.nu.edu/obesity/index.php


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Por

tal U

ser

Inte

rface

Grid ResourceBroker Service

Grid and Web

Protocols

Informationand

Data Services

DatabaseService Database

HPCor

Compute Cluster

Grid InformationServices, SRB

PortalClientStub

PortalClientStub

PortalClientStub

JDBC,Local, orRemote

Connection

Three-tiered service oriented architecture is accepted standard for accessing Grid and other services

Three-Tier Architecture


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Grid Portals

Launch, configureAnd control Application Interface

Workflow service

Open Grid Service Architecture Layer

Open Grid Service Infrastructure (web service component model) Resource layer

(slide by Dennis Gannon, modified)

Distributed Grid and Web Services

Registries and Name Binding

Reservations and Scheduling

Policy

Event/Mesg Services

security

Administrating & Monitoring

logging

Data Management services

Account services

Grid Orchestration

App InstanceApp InstanceApp Instance


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Data grid deployment


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Visualization of SRB

Mainframes

Supercomputers

Any platformDistributed Server

SQL server/Oracle/MySQL


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http://nucri.nu.edu/DHS/login.php

CHOIS – Childhood Obesity Informatics System


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CHOIS – Childhood Obesity Informatics System

Features of CHOIS- Web based forms

* BMI, Asthma, etc* Genomic info

- Combination of federated and central databases- Reports are available from anywhere anytime- Role based accessibility- Regulatory compliance (HIPAA, FERPA)- Mobile version is available- CMS, Drupal- Data integrator & DSS

Cyberintegrator, MotifNetwork, etc.- Alert system- Cyberenvironments

http://nucri.nu.edu/DHS/drupal/


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CHOIS

Web application Tools

DSS

Alert systemCyberIntegrator

NutrigramActivitygram

Training materials

Research International Collaboration

Immersive 3D Space

*Accessible through computers and smart phones

Child Health and Obesity Informatics System


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demo


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CHOIS – Child Health and Obesity Informatics System

Incorporating Genomic Information


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CHOIS – Content Management System, Drupal

http://nucri.nu.edu/DHS/drupal/


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CHOIS

Thank You

Cyberinfrastructure for CHOIS a Global Health initiative for obesity surveillance and control

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