PRACHI GUPTAPh.D. Chemical Engineering

University of Kentucky, Lexington, KYwww.linkedin.com/in/prachigupta1 | guptprachi@gmail.com | (402)-547-6534

OBJECTIVE: Research Scientist Result oriented and applied research projects, towards product development, material performance optimization, and

efficient design of experiment (DOE) including statistical data analysis. Cross cultural translational research towards the best possible results and application with a strong and growth

oriented professional environment.

EDUCATION Doctor of Philosophy (Ph.D.), Chemical and Material Engineering Expected August

2015University of Kentucky, Lexington, KY GPA: 3.4/4.00Thesis Topic: Synthesis and characterization of anti-oxidant conjugated poly (β-amino ester) micro/nanoparticles to suppress oxidative stress.

Bachelor in Chemical Engineering Graduated May 2010Institute of Chemical Technology (Formerly UDCT), Mumbai, India (1st class with distinction)

Summer Intern, Hindalco Industries (Aditya Birla Group), Renukoot, UP, India May - July 2009 Leaching efficiency in the purification process of aluminum extraction.

Summer Intern, Indian Institute of Technology, Chemical Engineering, Delhi, May-July 2008Extraction of metals from spent catalysts with application of digestion and reflux techniques to maximize extraction efficiencies.

PROFESSIONAL EXPERIENCEResearch assistant, University of Kentucky, Lexington, KY Jan 2011 – Present

Slow and steady drug release antioxidant conjugated pro-drug nanoparticles/nanogel formulation with other cross-linked systems towards prevention/ treatment of oxidative stress induced disorders including oral mucositis, skin cancer, Alzheimer’s, EPFR induced disorders.

Injection based casting of bulk polymeric gel systems with control over the thickness and mechanical and chemical properties based on material properties and compositions and terminal functionality.

Formulation of cross-linked antioxidant conjugated polymeric nanogels suspension with optimized size, degradation rate withincreased stability of hydrophobic pro-drug nano systems in aqueous systems.

Coordination of collaborative projects with different research groups to carry out translational research towards NIH Superfund Research Program

Extrusion based 3D printing including PLA/ABS based blend filament molding followed by structure printing.

Research assistant, Bluegrass Advanced Materials LLC, Lexington, KY Jan 2013-Present

Development, optimization and testing of pro-drug polymeric systems for commercial oral and topical cosmetic applications.

Research consultant, EZPrint LLC dba Geckotek May 2014-15

Contributed in Geckotek building plate via application based testing, present market requirement from personal to medically commercial needs.

Page 1

TECHNICAL EXPERIENCE Analytical: NMR, FTIR, HPLC, GPC, DLS, UV/VIS, DSC, tablet dissolution testing, Mass spectroscopy (LC-MS),

Electrophoresis, microparitcle size analyzer Microscopy: Optical, Fluorescence, SEM, TEM Proteins: Antibody production, radiolabeling, storage, stability, protein-carbonyl assay, Bradford, BCA Cell Culture: Human cell line culturing, cell material interactions, in vitro assays, radiolabeling and radiotracing,

staining, endotoxin detection, sterile and aseptic techniques, Seahorse XF analyzer (monitors real-time mitochondrial respiration), histological staining

Organic Chemistry: Protein conjugations, dye conjugations Software: CAD, LabVIEW, Aspen, Microsoft Office, ChemBioOffice, 3-D printing, Statistical analysis: SigmaPlot, Prism, graduate level course on Biostatistics with experience in Minitab. In vivo experiments: Experience with hamsters, cheek pouch treatment with drugs, scoring, post analysis of the

tissues including histology.

PUBLICATIONS Prachi Gupta, J. Zach Hilt, Thomas D. Dziubla. Quercetin conjugated Poly (β-Amino Esters) Nanogels for the

Treatment of Cellular Oxidative Stress (Acta Biomaterialia) (Submitted) Prachi Gupta, Mihail Mitov, J. Zach Hilt, Thomas D. Dziubla. Sustained Suppression of Mitochondrial Oxidative

Stress using Curcumin conjugated Poly (β- Amino Esters) Nanogels (Journal of Free Radical Biology and Medicine) (In process)

Prachi Gupta, Sandeep Ramineni, J. Zach Hilt, Thomas Dziubla, Joseph Wyse, Nihar Shah, Curcumin conjugated Poly (β- Amino Esters) gel microparticles to treat oral mucositis (Biomaterials) (In process)

Rohit Bhandari, Prachi Gupta, Thomas Dziubla, James Z. Hilt, Single Step Synthesis and Characterization of Curcumin functionalized Magnetic Iron Oxide Nanoparticles (Chemical Communication) (In process)

PATENT In process of submitting provisional patent for ‘Antioxidant conjugated biodegradable polymer microparticle

systems for the treatment of radiation induced injuries’ in co-authorship with Dr. Nihar Shah, Dr. Thomas D. Dziubla, Dr. J. Zach Hilt, Dr. Joseph Wyse

HONORS AND AWARDS 2nd position, Oral Presentation Competition, Biomaterials Day, Vanderbilt University, 2015 Pre-doctoral trainee: NSF-Superfund Research Project

CONFERENCE PROCEEDINGS Synthesis and Characterization of Curcumin Based Poly (β-Amino Ester) Antioxidant Nanoparticles to Control

Cellular Oxidative Stress, Prachi Gupta, Dr. J. Zach Hilt, Dr. Thomas Dziubla, AICHE, 2011, Minneapolis, MN Single Phase Reaction-Precipitation Systems for the Synthesis of Poly (β-Amino Esters) Nanogels, Prachi Gupta,

Dr. J. Zach Hilt, Dr. Thomas Dziubla, AICHE 2013, San Francisco, CA Sustained Suppression of Mitochondrial Oxidative Stress using Curcumin conjugated Poly (β- Amino Esters)

Nanogels, Prachi Gupta, Dr. Mihail Mitov, Dr. Allan D. Butterfield, Dr. J. Zach Hilt, Dr. Thomas D. Dziubla, Society for Biomaterials 2015, Charlotte, NC

LEADERSHIP EXPERIENCE Vice President, Society for Biomaterials, Local Chapter, University of Kentucky Served as secretary, event coordinator for non-techincal associations: Indian Student Association, Graduate Student

Council Representative, CMEGSA, International Student Council at University of Kentucky

TEACHING and MENTORING Teaching Assistant, University of Kentucky, Lexington, KY

Taught courses: Chemical Engineering Thermodynamics, Chemical Engineering Lab (junior and senior year students)

Mentored 2-3 undergraduate students each semester towards their undergraduate research projects and courses.

EXTRACURRICULAR

Page 2

Active member of a student band ‘KOSHISH’, Keyboard player. Active participant as a dancer in culture festivals with a 3rd year diploma degree in classical dancing. Editor of the award winning short film ‘PHASES’ screened at Diwali festival 2012, University of Cincinnati Website designer for our lab website: http://dziublalab.engineering.uky.edu/

Page 3