SUMMARY

CORE COMPETENCIES

SUMMARY of QUALIFICATION

• Lead responsible for all activities in Analytical department.

• Effective Communicator with excellent relationship management skills; possess a result oriented

attitude with analytical skills. Responsible for coordinating with global counterparts.

• To develop robust Analytical methods for raw materials, synthetic intermediates, drug substances

using chromatographic and spectroscopic techniques.

• Provide guidance to accomplish method validation for assays, related substances and residual solvents

by chromatographic (LC/GC) and spectroscopic (NMR) techniques for drug substances.

• Method development for quantification of Genotoxic/Potential genotoxic and organic volatile

impurities by using LC-MS, MS/MS, GC-MS, GC-HS-MS and NMR techniques at trace levels.

• Review of analytical method development documents, validation protocols and reports.

• Provide guidance on analysis of residual metals for the quantification at trace levels (ICP-MS/AAS).

• Involvement in isolation of impurities by preparative LC and characterization using spectroscopic

techniques.

• To carry out stability studies for Active Pharmaceutical Ingredients in obedience to ICH guidelines.

• Analytical technical expertise involving Tech transfer/Technical Stewardship activities of commercial

products for regulatory market (US and European).

• Responsible for ensuring delivery time-lines and adherence to customer quality and standards and

customer Relationship management.

• To ensure GLP and safety in analytical labs.

SANTOSH RANGRAO PATILI-302, Skyline apartment,

Sun pharma road, Atladara,

Vadodara-390012, Gujarat

Mobile No. 07574833724, 09886908610

Email ID : srp_sathi@yahoo.co.in

A Manager with extensive experience in the analytical development, method validation and

characterization of drug substances, intermediates, impurities and raw materials. Leading and managing a

team of scientists and research associates, focusing on analytical method development on Drug Substance,

intermediates etc. Writing and reviewing technical documents and develops analytical strategy,

communicate technical information to collaborating groups and manage the performance and career

development of direct reports/team members.

Technical Skills: Analytical method development, Analytical method validation, Technology transfer &

stability study.

Soft Skills: Team management, Coaching and talent development & management.

Master of Science (Analytical Chemistry) from Bharati University, Pune (2004)

Bachelor of Science from Shivaji University, Kolhapur. (2002)

RESPONSIBILITIES

EMPLOYMENT GRAPH- (Total ~12 yrs experience)

PUBLICATIONS

Detection and Quantification of Trace Level of Ethylenediamine in Morpholine and its Impact on the Quality of

a Pharmaceutical Candidate. International journal of pharmaceutical sciences Int. J. Pharm. Sci. Rev. Res., 33(2),

July – August 2015; Article No. 50, Pages: 242-247, Sajan P G, Rohith T, Santosh Patil, Kumara M N

Rapid, highly efficient and stability indicating RP-UPLC method for the quantitative determination of potential

impurities of carvedilol active pharmaceutical ingredient. International journal of pharmacy and pharmaceutical

sciences Sajan P G, Rohith T, Santosh Patil, Mantelingu K, Rangappa K S, Kumara M N

• Responsible for an Analytical team involved in Method development, Method Transfer and Validation

for various stages of drug development. Effective method development ensures that laboratory

resources are optimized, while methods meet the objectives required at each stage of drug

development.

• Facilitating scientific and technical discussions with team members and external collaborators to resolve

issues and communicating conclusions from stability studies.

• Participating with group members to explore innovative and improved ways for meeting the groups

deliverables while contributing to the scientific depth of the group.

• Build a highly talented team to drive successful integration of objectives.

• Mentor and coach the existing team and developing a pipeline of high caliber and talented professionals

with right skillsets. Drive career advancement plans, objective / goal setting, deciding on the Goals.

• Active participation in internal forums involving senior management to discuss and resolve issues

related to facility, instrumentation, capabilities and other areas. Participate in formulating and

reshaping strategies that affect to organizations growth, operations and future plans.

• Active involvement in Investigating OOS’s from R&D perspective.

• Setting up in-process control criteria for chemical reactions, specification for raw materials,

intermediates and Drug substances.

• Leading, managing & monitoring performance of team to ensure efficiency in various aspects.

• Manage analytical requirements for project delivery.

Onyx Scientific-IPCA Laboratory Ltd, Vadodara, Gujarat

Manager, Analytical Development (Oct 2014 to present)

Biocon Ltd, Bangalore, Karnataka

Deputy Manager, Analytical Development (Sep 2013 to Sep 2014)

AstraZeneca India Pvt Ltd, Bangalore, Karnataka

Associate Research Scientist-2, Analytical Sciences (Jul 2007 to Aug 2013)

Indoco Remedies Ltd, Navi Mumbai, Maharashtra

Research officer, Analytical Development (Sep 2005 to Jun 2007)

Sai Life Sciences, Hyderabad

Analyst, Analytical Development (Mar 2005 to Aug 2005)

Glenmark Research Centre, Navi Mumbai, Maharashtra

Reseach associate, Analytical Development (Aug 2004 to Feb 2005)

AWARDS & RECOGNITION

TRAINING & WORKSHOPS

INSTRUMENTS & TECHNIQUES

SOFTWARE KNOWLEDGE

PERSONAL

Permanent Address: 214, A/P -Khochi, Tal-Hatkanangle, Dist-Kolhapur, 416110, Maharashtra

HPLC - Agilent, Waters and Shimadhzu

UPLC, UHPLC - Agilent, Waters

NMR - Bruker Topspin (300, 400 MHz)

GC/MS - Agilent, Perkin Elmer

GC - Agilent, Perkin Elmer

GC/HS - Agilent, Perkin Elmer

GC-LTM - Agilent

LC/MS, LCMSMS, UHPLCMS - Agilent Single &

Triple quardupole, Thermo

Date of birth : 07/10/1981

Language known : English, Hindi and Marathi

Hobbies : Drawing, sketching, playing cricket, volleyball, chess

• ACD LABS – MS Fragmentor, NMR Predictor/Processor

• Structure Elucidator, ChemSketch and ISIS Chem Draw

• Sci Finder

• Electronic Lab Note Book, ADMS and LDMS

Best Scientific project award - 2008, AstraZeneca, Bangalore.

Best Scientific project award - 2011, AstraZeneca, Bangalore.

Best Science award – Nomination - 2011, AstraZeneca, Bangalore.

Safety Poster competition awards - 2nd prize (2009), 1st prize (2010).

Best project award - 2013, AstraZeneca, Bangalore

Special award for project LEOPARD - 2013, AstraZeneca, Bangalore.

E-Magazine Sameeksha Award, AstraZeneca, Bangalore.

Safety Award, AstraZeneca, Bangalore.

Polarimeter - Rudolph

KF Titrator - Metrohm, Metler Toledo

Autotitrator - Metrohm, Metler Toledo

UV Visible Spectrophotometer - Perkin Elmer

Preparative HPLC - Waters

IR - Perkin Elmer

AAS - PerkinElmer AA-800

MS-QTOF - Agilent

LCMS school 3 days workshop held by Water’s – AstraZeneca, Bangalore

Structural Interpretation of Organic compounds by Mass Spectroscopy - AstraZeneca

Column Characterization 1 day workshop – Nobua Tanaka, LCGC Gurukul chromatography

Agilent HPLC trouble shooting training – Indoco Remedies

Leadership capabilities training – AstraZeneca, Bangalore

Communication and presentation skills – AstraZeneca, Bangalore

Negotiation and influencing skills – AstraZeneca, Bangalore

Time Management training – AstraZeneca, Bangalore