CV 2019 updated - Neoscriber Anna Nazarenko Kashfi K, and Nazarenko A. (2006) Nitric oxide-releasing

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Transcript of CV 2019 updated - Neoscriber Anna Nazarenko Kashfi K, and Nazarenko A. (2006) Nitric oxide-releasing

  • Page 1 of 27

    CURRICULUM VITAE Name: Khosrow Kashfi, PhD, MSc, FRSC Home Address 3 Bonaire Drive, Dix Hills, NY 11746 and Phone: 516-413-5450 Work Address Department of Molecular, Cellular and Biomedical Sciences and Phone: The Sophie Davis School of Biomedical Education City University of New York School of Medicine 160 Convent Avenue, Harris Hall, Suite 205C

    New York, NY 1003, USA Tel: 212-650-6641 FAX: 212-650-7692 email: Kashfi@med.cuny.edu Education: High School: Seaford College, Petworth Sussex, England, Graduated 1971

    Undergraduate: Kingston Polytechnic, Surrey, England, B.Sc. (Hon.) in Chemistry, 1974

    Postgraduate: Cranfield Institute of Technology, Bedford, England, M.Sc. in Polymer Physics and Engineering, 1976

    University of Tennessee, Memphis TN Ph.D. in Pharmacology, 1992

    Postdoctoral: Cornell University Medical College (1993-1995) Rockefeller University (1995-1997) Societies, Honors and Awards: 1974-1976 Full Scholarship for M.Sc. degree

    1985 Licentiate of The Royal Society of Chemistry, England

    1993 Full member, Biochemical Society, England

    1996 Sigma Xi

    1996 Regular member, Society for Experimental Biology and Medicine

    1997 Member, American Chemical Society

    2006 Instructor of the year award by the 2006 graduating class of The City University of New York Medical School

    2010 Elected Fellow of The Royal Society of Chemistry, England

    2011, 2012 Minority-Serving Institution Faculty Scholar in Cancer Research 2014 Award from The American Association for Cancer Research

  • Page 2 of 27

    Employment:

    1999-Present City University of New York School of Medicine, The Sophie Davis School of Biomedical Education,

    Associate Medical Professor, Department of Cellular, Molecular, Medical Sciences Tenure, 2007

    1999-2018 City University of New York Medical School, The Sophie Davis School of Biomedical Education,

    Chemistry Program Director,

    2009-2013 Director, Medical and Physician Assistant Pharmacology Courses

    2002-2006 Director, Medical Biochemistry Program

    2003-Present State University of New York at Old Westbury Adjunct Full Professor of Organic Chemistry & Biochemistry

    2006-Present State University of New York at Stony Brook Adjunct Associate Professor, Department of Medicine Division of Cancer Prevention 1997-2005 The Rockefeller University, Laboratory of Clinical Microbiology and

    Immunology, Adjunct Faculty 1997-1999 Department of Physical Sciences, Kingsborough Community College of The City University of New York, Assistant Professor 1995-1997 Bronx Lebanon Hospital, Bronx, New York, Course Coordinator in Pharmacology for The Physician Assistant Program 1994-1997 Department of Natural and Applied Sciences, LaGuardia Community College of The City University of New York, Adjunct Assistant Professor 1993-1995 Department of Medicine, Division of Digestive Diseases, The New York Hospital-Cornell Medical Center,

    Postdoctoral Fellow in Medicine 1987-1992 Department of Pharmacology, College of Medicine, University of Tennessee, Memphis, Teaching Assistant 1985-1986 Department of Medicinal Chemistry, University of Tennessee, Memphis, H.S. Van Vleet Research Fellow in Medicinal Chemistry 1984-1985 Christian Brothers University, Memphis, Tennessee, Lecturer in Chemical Engineering 1980-1984 Loxdent Chemical Company, Ltd., England, Processing Engineer

    1976-1980 Department of Mechanical Engineering, Imperial College of Science and Technology, London University, England, Research Assistant

  • Page 3 of 27

    Teaching Experience: A. The following courses have been taught by me at various times: 1. Organic chemistry I & II 6. Medicinal organic chemistry II 2. Chemistry for Allied Health Students 7. Physiology 3. General Chemistry I & II 8. Thermodynamics I & II 4. Biochemistry 9. Polymer science 5. Pharmacology (Entire PA Program, 10. Material selection course director) B. Courses and topics taught at CUNY Medical School 1999- current General Chemistry, entire course

    Organic Chemistry, selected topics As Program Director, I reorganized the courses and introduced small group study sessions, “Peer-Led Team Learning”. This has proved to be very successful. Also, students get periodic Progress Reports, which informs them of how they are doing in class and what steps are needed to improve standing. 2000-current GI Pharmacology (entire unit) 2000-2004 GI Physiology (entire unit) 2000-2002 Neuropharmacology 2002, 2005- Cardiovascular Pharmacology present Drugs used in the treatment of heart failure, hypertension,

    hypercholesterolemia 2000-2008 Conducted 10 PBL sessions each year in pharmacology, and the only PBL session in GI physiology 2002-2004 Biochemistry: Cytochrome P450s, Gluconeogenesis,

    Metabolic Interrelationships

    As Program Director, I introduced genetic disease presentations by all students, worked very closely with our own faculty and faculty from Cornell University Medical College to ensure a course that met all expectations of the National Board of Medical Examiners. I also introduced 6 PBL sessions (conducted by myself), the cases for which were purchased from Harvard Medical School. In 2003 mini-boards in biochemistry, 20% of the class scored above the 90th percentile. 2004-2009 Molecules-to-Cells: This is a new course in which I have taught the

    following topics: Protein-Ligand interactions; Receptors; Enzymes, enzyme kinetics, enzyme regulation; Glycolysis; Fatty acid synthesis, Gluconeogenesis, Major Lipids: Fatty acids, Eicosanoids; Cholesterol and its derivatives; Liporproteins and cholesterol transport, Reactive oxygen species.

    As Chair of our Curriculum Committee, I was intimately involved in the formulation of this course and its implementation. 2005- 2018 Bio-Organic Chemistry

    This is a new one-semester course which I introduced in 2005. This course integrates organic and biochemistry, diffusing the boundary between the two areas which should help better prepare our students for entry into our Molecules-to-Cells course.

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    Faculty Development Workshops 1) October 1999--Ovid Medline for Efficient, Research-Targeted Medical Literature Searching. Instructor, CCNY Assistant Professor Claudia Lascar, Science Engineering Librarian. 2) November 1999--Deborah Danoff, M.D., AAMC, Assistant Vice-President in Medical Education 3) February 2000--˜Writing Clincial Vignettes and USMLE-Type Examination Questions. Workshop Leaders, Susan M. Case and David. B. Swanson, Ph.D. Association of American Medical Colleges 4) March 2000--Guidelines for Creating Teaching Portfolios, Ellen Smiley, Ph.D., CCNY Assistant Provost 5) November 2000--CurrMit (Curriculum Management Information Tool) Al Salas, Project Director/Senior Staff Associate, Division of Medical Education 6) December 2000—CCNY Anti-sexual Harassmant Student Supervision: The following students have been mentored by me (1999-present): Master’s Thesis:

    Nicole E. Neptune, Department of Chemistry, City College of CUNY (2000).

    Title: Comparative Effects of Hemipalmitoylcarnitinium Stereoisomers on Hepatic Mitochondrial Carnitine Palmitoyltransferases.

    PhD Thesis:

    Member of PhD dissertation committees: Ms. Phyllis J. Langone, Department of Biochemistry, College of Staten Island, City University of New York (2008-2010)

    Title: Inhibiting brain tumor progression via strategically targeted curcumin.

    Ms. Mihwa Na, Department of Chemistry, City College of New York, City University of New York (2011-2017)

    Title: Pharmacological Antagonism And The Olfactory Code.

    Mr. Sumit Mukerjee, Department of Biochemistry, College of Staten Island, City University of New York (2008-2018)

    Title: Strategies involving the food-derived agent curcumin to eliminate brain cancer

  • Page 5 of 27

    McLipkin Fellowship:

    Preeti Parhar, (2000).

    Title: Left Ventricular Hypertrophy: An Independent Risk Factor For Cardiovascular disease Beena Mathaikutty (2004)

    Title: Mycobacterium ulcerans effects on the immune response via quantitative data of TLR2, TLR3, TLR4 and TLR 9

    Galina Borodulina, (2006).

    Title: Development of a method to measure T-cell activation in vivo

    Barry Ladizinski, (2006).

    Title: Modified Urinary Nucleosides as Monitors of Metabolism & Disease

    Postdoctoral Fellows Trained:

    Niharika Nath, PhD Gao J, PhD

    Ravinder Kodela, PhD Liu X, PhD

    Mitali Chattopadhyay, PhD

    Independent Study: The following students have worked in my lab (2002-current) Georges Labaze

    Nath N, Labaze G, Rigas B, and Kashfi K. (2004) NO-donating aspirin (NO-ASA) modulates ß-catenin expression in cultured human leukemia cells. Biochem. Biophys. Res. Comm 326, 93-99.

    Rashida Vassell

    Nath N, Vassell R, Rigas B, and Kashfi K. (2004) NO-ASA strongly inhibits Wnt/ß-catenin signaling in breast cancer MCF-7 cells. Abstract presented at AACR: Third Annual International Conference on Frontiers in Cancer Prevention Research, Seattle, Washington.

    Anna Nazarenko

    Kashfi K, and Nazarenko