cutting edge research on “TheWednesday 21, December, 2016 Main Hall Class 1 Workshop 8:30- 9:00...

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Transcript of cutting edge research on “TheWednesday 21, December, 2016 Main Hall Class 1 Workshop 8:30- 9:00...

  • Dear Colleagues,

    It is an honor to serve as the president of the 12th Annual Meeting of the Iranian

    Division of the International Association for Dental Research (IADR). It is a pleasure

    to have such a large group of researchers from different domains, including

    Craniofacial Biology, Biomaterials, Caries and Epidemiologic researches,

    Prosthodontics and Restorative Dentistry, Implants, Pathology, Biology and

    Regeneration of the Pulp, Periodontics, Pedodontics, Stem Cells and Laser. All

    presentations and workshops will be held at the Imam Ali (PBUH) Cultural Center and

    are open for all to attend.

    Each scientific group has the option to invite a keynote speaker to give an overview of

    their research in their area of expertise. Delegates can benefit from these presentations

    by getting an overall understanding of what is currently being done in other disciplines.

    The meeting will enable participants and researchers to expand their national and

    international collaborations and will also provide an opportunity for sharing their

    valuable knowledge and experiences.

    During the opening ceremony, we will have honor of presenting a video clip from the

    outstanding icon and father of the modern orthodontics of Iran, Professor Ali A.

    Bahreman.

    Our distinguished lecturer and keynote speaker Professor Lobat Tayebi will present her

    cutting edge research on “The Application of Microfluidic Approach in VEGF

    Delivery for Treatment of Critically-Sized Craniofacial Defects” and from the

    Periodontal scientific group, keynote speaker Professor Gholamali Gholami will

    present his innovative research on “Clinical Concepts in Peri-Implant Plastic Surgery”.

    I would like to express my gratitude to the vice-chair, Dr. Behnaz, the head of the

    scientific committee, Dr. Mashhadi-Abbas, the head of the executive committee, Dr.

    Torkaman, and the head of the student committee, Dr. Malekmohammadi. We would

    also like to thank the President of the Iranian Division of IADR, Dr. Banava, our

    Golden Sponsors including Parseh Ettekal Co., Diba Teb Pars Co. and many other

    friends whom we were not able to mention here.

    Best regards

    Massoud Seifi DDS, MSD, MS Med Edu

    President of the 12th Annual Meeting, Iranian Division of IADR

  • Prof. Sepideh Banava Prof. Massoud Seifi

    President of iran division of IADR Congress President

    Dr. Fatemeh Mashhadiabbas Dr. Mohammad Behnaz Dr. Mahnaz Torkaman

    Head of Scientific Committee Congress Vice President Head of Executive Committee

  • Organizing Committee:

    Congress President: Prof. Massoud Seifi

    Congress Vice President: Dr. Mohammad Behnaz

    Head of Scientific Committee: Dr. Fatemeh Mashhadiabbas

    Head of Executive Committee: Dr. Mahnaz Torkaman

    Vice Executive Director: Dr. Azam Torabi

    Congress Advisors: Dr. Ghasem Ansari, Dr. Sepideh Banava, Dr. Mahtab Nouri

    Poster Committee: Dr. Mahsa Malekmohammadi, Dr. Tayebeh Rojhanian

    Workshop Committee: Dr. Mahnaz Torkaman , Dr. Azam Torabi

    Registration Committee: Mr. Majid Nouri, Ms. Farzaneh Firouz, Ms. Jamileh Toghi, Ms. Hormat Nilchian

    Graphic & Design: Dr. Azam Torabi, Dr. Mahsa Malek moahammdi, Dr. Tayebeh Rojhhanian, Ms. Fatemeh Rafati ,

    Ms Masoomeh Hadadi , Mr. Javad Sabbagh

    Publication Committee: The General Office For Health of Tehran Municipality

    Ceremonial Committee: Dr. Ardavan Parhizkar

    Audio-Visual & Media Committee: Mr. Babak Geranmaye

    English Editors: Ms. Sorayya Sedigh, Ms. Kiana Gashas

    Student Executive Members:

    Dr. Saeedreza Motamedian, Dr. Golnaz Nahvi, Dr. Zahra Tehrani, Dr. Setareh Sohrabi, Dr. MohammadHossein Farahani,

    Dr. Nazanin Sanagou, Dr. Shiva Safari, Dr. Arezoo Mahdian, Ms. Afshin Hosseinzadeh, Ms. Orkideh Alavi, Ms. Shalale

    Nourshad, Mr. Hamidreza Moslemi, Mr. Masih Lazar, Ms. Aida Kheiri, Ms. Samira Hosseini, Ms. Mobina Kamani, Ms.

    Maryam Zohari, Ms. Fatemeh Alirezaei, Ms. Lida Kheiri, Mr. Hossein Mohammad Rahimi, Mr. Shervin Shafiee, Mr.

    Ahmad Soufi, Ms. Hananeh Safiaghdam, Mr. Amirreza Hashemi, Mr. Amir Fahimipour, Dr. Kiana Kroupi, Mr. Bahram

    Ardalani, Mr. Rastin Ivani, Mr. Amirhossein Ardani, Ms. Shirin Etminani, Mr. Shervin Hejazi, Mr. Mahmoud Dashti, Ms.

    Melika Goudarzi, Ms. Farnaz Mobini, Ms. Sooreh Masoumi, Mr. Sajad Haghi, Mr. Mohammad Payami, Ms. Nikta Jafari

    pour, Ms. Faeze Salehabadi, Ms. Nika jafaripour,

    Iranian IADR Officers:

    President: Dr. Sepideh Banava

    President-Elect: Dr. Fatemeh Mashhadiabbas

    Treasurer: Dr. Ghasem Ansari

    Councilor: Dr. Sepideh Banava

    Immediate Past President: Dr. Ghasem Ansari

    Secretary: Mr. Sepanta Hosseinpour

  • Scientific Committee & Abstracts Reviewers (in alphabetic order):

    Dr. Ghasem Ansari, Dr. Saranaz Azari, Dr. Ali Baghalian, Dr. Mohammad Behnaz, Dr.Somayeh Dastanpour,

    Dr. Narges Ghaazi, Dr. Hadi Ghasemi, Dr. Jamile Ghoddousi, Dr. Sareh Habibzadeh, Dr. Haleh Heshmat, Dr.

    Tabasom Hooshmand, Dr. Mozhgan Izadi, Dr. Taherehsadat Jafarzadeh Kashi, Dr. Kambiz Kamyab, Dr.

    Mohhamadreza Khami, Dr. Haleh Kazemi, Dr. Abbasali Khademi, Dr. Leila Nasiri Khanlar, Dr. Arash

    Khojasteh, Dr. Masoud Falahinejad, Dr. Mina Matlabnejad, Dr. Azita Mazaheri, Dr. Masoumeh Mehdipour,

    Dr. Mahshid Mohammadi Basir, Dr. Simin Mohebi, Dr. Ahmad Moghareh Abad, Dr. Noushin Mohtasham,

    Dr. Masoud Parirokh, Dr. Narges Naghsh, Dr. Reza Nahidi, Dr. Rouhollah Naseri, Dr. Ali Rashidian, Dr.

    Monireh Rashidan,Dr. Massoud Seifi, Dr. Masoud Saatchi, Dr. Nosratollah Saghravanian, Dr. Katayoun

    Sargeran, Dr. Sima Shahabi, Dr. Kaveh Seyedan, Dr. Fahimesadat Tabatabaei, Dr. Soodeh Tahmasbi.

  • Wednesday 21, December, 2016

    Main Hall Class 1 Workshop

    8:30-

    9:00 Registration

    9:00-

    10:30

    Opening Ceremony

    Keynote Lecture

    Prof. Aliakbar Bahreman- video conference Dr. Gholamali Gholami

    10:30-

    11:00

    Coffee Break

    11:00 –

    13:00

    Endo_LASER

    Poster Presentation Workshop

    -

    Chairman Dr.Mohammad Asnaashari,

    Dr.Payam Peimanpour, Dr.Katayoun Kalhori

    Chairman Dr.Zahra Ghorbani

    Moderator: 1. Dr.Nahid mohmmadzadeh Akhlaghi 2. Dr. Maziar Mir 3. Dr.Ardavan Parhizkar 4. Dr. Pegah Khzaei 5. Dr. Amirreza Beglou 6. Dr. Samira Hosseini

    1. Dr.Mahsa Malekmohammadi 2. Dr.Mitra Ghazizadeh Ahsaie 3. Dr.Hoda Bahramian 4. Dr.Zahra Momeni 5. Dr.Sajad Ansari Fard 6. Dr. Zahra Yaghoubi 7. Dr. Ayda Kheyri 8. Dr. Fatemeh sharifi

    -

    13:00 –

    14:00 Lunch

    14:00-

    16:00

    Oral Health

    Poster Presentation

    Workshop Chairman Dr. Hadi Ghasemi, Dr.Mehdi Nasibi, Dr.

    Fariborz Bayat

    Chairman Dr.Nazanin Mahdavi

    [

    1. Dr. Marzieh Deghatipour

    2. Dr. Baharak Amanzadeh

    3. Dr. Maryam Sadeghipour

    4. Dr. Mahdia Gholami

    5. Dr. Zahra Ghorbani

    6. Dr. Azim M.

    7. Dr. Homa Fathi

    1. Dr. Navid Saadatfar 2. Dr. Mahnaz Torkaman 3. Dr. Bahareh Tahani 4. Dr. Lina Zarifpour 5. Dr. Fatemeh Hosseini 6. Dr. Arghavan Tonkaboni 7. Dr. Mohammad Noruzian 8. Dr. Saranaz Azari-Marhabi 9. Dr. Hamidreza Moslemi

    Dr. Shahriar

    Shahab &

    Dr.Soodeh

    Sarikhani

    16:00 –

    16:30

    Coffee Break

    Dr.Jamile

    Ghodousi

    Craniofacial Biology & Stem

    Cells Dental Material

    16:30 –

    18: 30

    Chairman Dr.Maryam Yeganeh,

    Dr.Maryam Rezaei Ra

    Chairman Dr.Tabatabaei,

    Dr.Mostafa Fatemi,

    Dr.Soulmaz Eskandarion

    1. Dr. Pantea Nazeman

    2. Dr. Hamidreza Moslemi

    3. Dr. Zahra Aghamohammadi

    4. Dr. Sepanta Hosseinpour

    5. Dr. Masih Lazar

    1. Dr. Alireza Hadi

    2. Dr. Niloofar Kianvashrad

    3. Dr. Setareh Sohrabi

    4. Dr. Manijeh Mohammadian

    5. Dr. Mohammad-Ali Keshvad

  • Thursday 22, December, 2016

    Main Hall Class 1 Workshop

    8:30 -

    10:30

    Oral Health

    Poster Presentation

    Chairman Dr.Mohammadreza Khami, Dr. Afsaneh

    Pakdaman,, Dr.Hossein Hesari

    Chairman Dr.Dianat, Dr.Haeri

    d

    1. Dr. Mohammad Khoshnevisan

    (Keynote)

    2. Dr. Hamid Zafarmand 3. Dr. Hadi Ghasemi 4. Dr. Ali Kazemian 5. Dr. Sara Hajian 6. Dr. Shervan Shoaee 7. Dr. Hediyeh Toutouni

    1. Dr. Elham Fakhari 2. Dr. Fateme Mohammadian 3. Dr. Parishad Bahmani 4. Dr. Mamak Adel 5. Dr. Melika Ghandehari 6. Dr. Farshad Dehnavi 7. Dr.Farnoush Fotovat 8. Dr. Samin Karimi Yeganeh 9. Dr. Amineh Ghaznavi

    Dr.Kaveh

    Seyedan

    10:30-

    11

    Coffee Break

    11:00-

    13:00

    Oral Surgery Poster Presentation Workshop

    Dr. Omid Moghadas

    Chairman

    Dr.Mir Mohammad Sadeghi, Dr.Reza Tabrizi

    , Dr.Abbas Karimi

    Chairman Dr.Zahra Ghorbani

    1. Dr. Lobat Tayebi (Keynote)

    2. Dr.Amir Mansour Shirani

    3. Dr.Behzad Salari

    4. Dr.Tayebe Rojhanian

    5. Dr.Pooneh Mohebbi

    6. Dr.Negar Razzaghi

    1. Dr. Nassim Hashemi 2. Dr.Maryam Elyasi 3. Dr.Farnaz Bagheri Taddi 4. Dr. Sara Hajian 5. Dr.Mohammad Mehdi Naghibi Sistani 6. Dr.Hajar Shekarchizadeh 7. Dr.Danoosh Dehghanian 8. Dr.Marzieh Ghaiour 9. Dr.Mahsa Malekmohammadi 10. Dr.Sediqe Shafiei

    13- 14 Lunch

    Pathology & Oral Medicine Dental Materials

    14:00-

    16:00

    Chairman Dr.Soudabeh Sargolzaei, Dr.Pouria Motahari ,

    Dr.Nasim Taghavi

    Chairman Dr. Amir Ghasemi, Dr.Noje Dehian,

    Dr.Marjan Behrouzimanesh

    Workshop

    Dr.Kaveh

    Saati 1. Dr. Muhammad.Shahzad 2. Dr. Arghavan Etebarian 3. Dr. Somayyeh Azimi 4. Dr. Masoume Fayazi Boroujeni 5. Dr. Mobina Najafifard 6. Dr. Soofieh Moallemi Pour 7. Dr. Reihaneh Nikseresht

    1. Dr. Zahra Namazi 2. Dr. Fateme Razazpour 3. Dr. Parisa Amdjadi 4. Dr. Taraneh Faghihi 5. Dr. Mehrsima Ghavami Lahiji

    16 -

    16:30 Coffee Break

    16:30-

    Restorative – Cariology Orthodontics-Pediatrics

    Chairman

    Chairman

    Dr.Torab zadeh, Dr.Najafi,

    Dr.Shahin Kasraei

    Dr.Mahtab Nouri, Dr.Shokatbakhsh,

    Dr.Mohammad Behnaz

  • 18: 30 1. Dr. Maryam Koopaie 2. Dr. Hossein Bagheri 3. Dr. Deepak Roy 4. Dr. Amir Fahimipour 5. Dr. Ab.Tabatabaei 6. Dr. Reza Eftekhar Ashtiani

    1. Dr. Negin Matini 2. Dr. Hosein Mohammad Rahimi 3. Dr. Mohammad Norouzian 4. Dr. Sara Eslami 5. Dr. Nazanin Bahrololumi 6. Dr. Shiva Shekarian

    Friday 23, December, 2016

    Main Hall Class 1 Workshop

    8:30 -

    10:30

    Ortho-Pediatrics Poster Presentation

    Chairman Dr.Masoud Falahi nejad,

    Dr.Tahereh Hossein zadeh,

    Dr.Fariborz Amini

    Chairman Dr.Ardavan Parhizkar,

    Dr.Zahra Yagdari

    Dr. Kazem Dalaei

    &

    Dr. Mohammad

    Behnaz

    1. Dr. Ghasem Ansari (Keynote) 2. Dr. Azita Tehranchi 3. Massoud Seifi 4. Alireza Jafari-Naeimi 5. Ali Baghalian

    6. Sarvin Sarmadi

    1. Dr. Azam Torabi 2. Dr.Golnaz Nahvi 3. Dr. Hannaneh Safiaghdam 4. Dr. Ehsan Esnaashari 5. Dr. Saba Sefidabi

    6. Dr. Maryam Pirmoradian-Najafabadi

    10:30-

    11

    Coffee Break

    11:00-

    13:00

    Periodontics And Implantology Poster Presentation Workshop

    Dr. Shahram Azimi

    Chairman

    Dr.MohammadrezaTalebi,

    Dr.Behzad Houshmand,

    Dr.Mansour Meimandi

    Chairman Dr.Kazem Dalaei,

    Dr.Soudeh Tahmasebi

    1. Dr. Omid Moghaddas 2. Dr. Shervin Shafiei 3. Dr. Nasrin Esfahanizadeh 4. Dr.Ghazaal Kamyabjou 5.Dr. Maryam Rabbani

    1. Dr. Reza Yarmohammadi 2. Dr. Reza Lotfi 3. Dr. Saeedeh Akhoundan 4. Dr. Lida Kheiri 5. Dr. Reza Yazdani 6. Dr. Bahram Ardalani

    7. Dr. M. Pakkhesal

    13-

    13:30 Closing Ceremony

  • Keynote Lectures

    Clinical Concepts in Peri-Implant Plastic Surgery

    G.Ali.Gholami, DDS, MS, Periodontist1,2,3

    1. Professor of Periodontics, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Founder of Perio Implant Fellowship, Shahid Beheshti University of Medical Sciences, Tehran, Iran 3. Director of Perio - implant fellowship program, Shahid Beheshti University of Medical Sciences, Tehran, Iran 4. Founder of the Iranian osteology symposiums

    Objectives: To our knowledge, there has been no report of bone-added periodontal plastic surgery for root coverage procedures in humans. The aim of the present investigation was to present a technique with a combination of bone substitute, CTG, and CPF to create some space for osteoconduction and soft tissue coverage over denuded roots.

    Methods: A 23 year-old female was referred to our private clinic with a severe class II Miller recession and a lack of attached gingiva. The suggested treatment plan comprised of root coverage combined with xenograft bone particles.

    Results: The grafted area healed well and full coverage was achieved at the 12-month follow-up visit. Bone-added periodontal plastic surgery can be considered as a practical procedure for management of deep gingival recession without buccal bone plate.

    Conclusions: The main advantages of RPC graft can be summarized as follows: achieving a stable primary closure during bone remodeling, saving or creating sufficient vestibular depth, making adequate keratinized gingiva on the buccal surface, and being aesthetically pleasing.

  • Dental Public Health: The Past, Present and Future

    Mohammad H. Khoshnevisan, DMD, DPHDent, DrPH, PhD, ADI Fellow 1, 2, 3

    1 Director, Preventive Dentistry Research Center, Dental Research Institute, School of Dentistry, Shahid Beheshti

    University of Medical Sciences (SBMU), Tehran, Iran. 2 Associate Professor and Chair, Dental Public Health Program,

    Community Oral health Department, School of Dentistry, SBMU, Tehran, Iran. Director, WHO Collaborating Center for

    Training and Research in Dental Public Health, School of Dentistry, SBMU, Tehran, Iran

    The history of mankind starts with fight for life when he was at the mercy of nature with no effective means

    of protection. It took ages for ancient people to come up with traditional remedies. Efforts on preventive care

    dates back to Hippocrates time (480 BC). Although, many writings dealt with tooth and gum diseases, it was

    not until 9th century that “Siwak” or “Miswak” the ecological toothbrush was introduced and highly

    recommended by scientific and religious sources for oral hygiene and better dental care. By enhancing the

    process of learning and improvement of research; gradually, the health knowledge was greatly intensified.

    Yet, conventional dentistry has traditionally been curative rather than being preventive oriented with no

    attention to general public.

    Dental Public Health as a recognized dental specialty is mainly focused on prevention and control of dental

    diseases, promotion of oral as well as overall health and quality of life for entire communities on a group by

    group basis. Currently, oral diseases are highly prevalent and dental care expenditure is escalating despite the

    fact that they are preventable. Population-based improvements in oral health outcomes are possible through

    multiple costs-saving interventions. To achieve this, Dental Public Health leadership and infrastructure is

    absolutely needed to improve and protect the public’s oral health. Nevertheless, this discipline with high

    impact on the health of entire population is still under-supported and facing numerous challenges.

    Governments and academia play central role in improving the current situation and planning for the brightest

    future oral health. In part of the governments, strong policy development is expected in order to guarantee

    the effective continuation of the population-based preventive programs. In part of academia, serious

    consideration is needed on the quality and quantity of the future dental workforce which should be extended

    beyond professional and national boundaries.

  • Application of Microfluidic Approach in VEGF Delivery for Treatment of Critically-Sized Craniofacial Defects

    Lobat Tayebi1

    1. Marquette University School of Dentistry, Wisconsin, USA

    Objectives: Using growth factors in treatment of critically-sized oral and carniomaxillofacial defects has

    generated great enthusiasm and an intensive research effort leading to recent clinical trials, many of which

    have yielded unsatisfactory outcomes. Interestingly, the trials with the most satisfactory results have shared

    a common denominator: the presence of a vehicle for controlled growth factor delivery.

    Methods: VEGF (Vascular Endothelial Growth Factor) is a vital angiogenic agent that can be used in

    combination with other growth factors, such as BMP-2, to enhance bone regeneration. VEGF, when injected

    into the body, has a short half-life of 90 minutes. Bolus injection of VEGF can induce inappropriate

    neovascularization in avascular areas and excess exposure to VEGF may promote vascularization in unwanted

    sites and enhance the risk of tumor growth. Moreover, due to the short half-life, the vasculature formed is

    usually transient and disappears over time. Thus, localized and sustained delivery of VEGF is extremely

    important for bone regeneration.

    Results: Currently, delivery systems are imperfect and limited technologies exist for precise encapsulation of

    VEGF and its sustained and controlled release. Although a variety of vehicles have been investigated for VEGF

    delivery, a robust predictive method has yet to be achieved. Current methods for fabrication of particle

    vehicles such as conventional bulk mixing methods result in extremely polydisperse particles that exhibit

    various physicochemical properties that are difficult to control. Moreover, these methods require further,

    and often complicated, post-processing steps.

    Conclusions: This presentation reviews the applications of microfluidic approach and its innovations in

    biomanufacturing and discusses the potential this approach may offer to develop a method that creates

    precise customized encapsulated VEGF particles with well-regulated release rates. There are specific

    challenges in using microfluidic platform for this purpose due to the large size of VEGF and other limitations,

    which will be elaborated in this presentation. Such precise VEGF-loaded particles can be embedded in

    scaffolds and implants designed for critically sized defects and used along with other growth factors to

    promote tissue regeneration and repair in oral and craniomaxillofacial injuries.

  • Safety and complications in pediatric dental sedation

    Ghassem Ansari DDS, MSc, PhD (Glasgow), FHD (UCLA)1

    1. Professor, Head of Sedation & Hospital Dentistry Unit, Dept of Pediatric Dentistry, Dental School, Shahid Beheshti Medical University, Tehran, Iran

    Objectives: Various levels of sedation have been employed by clinicians to help treating uncooperative individuals. The aim of this article is to discuss safe guard and complications when sedating children for dental procedures.

    Methods: Data were collected from 20 studies carried out at the Fellowship Unit, Department of Pediatric Dentistry at SBMU, Tehran, between 2008 to 2016. International guidelines which are implemented in US hospital, and in particular the state of California, were used. Appropriate, efficient and reliable monitoring procedures were adopted in order to evaluate the potential closer evaluation reducing the risks involved.

    Results: Clearly, a fully equipped clinic along with well-trained operators will dramatically reduce the risks of complications following the induction of various levels of sedation. Management of such complications is considered as another important task which requires appropriate training and preparedness. Confidence in the management of complications like laringospasm or bronchospasm is a must for anyone who is licensed to treat patients under sedation. The use of a pretracheal stethoscope and its proper clinical application has substantially increased the safety of this procedure.

    Conclusions: The safety of any procedure is the priority with sedation being at the forefront of the dental procedures for safety of the patients treated.

  • Oral presentations

  • Endo-LASER

    Incidence of Dentinal Crack Formation

    PRESENTER: Nahid Mohammadzadeh Akhlaghi

    AUTHORS: N. S. Mohammadzadeh Akhlaghi2, 1, A. Delvarani2, V. Noroozi2, Mohebbi2

    1. Endodontics,Islamic Azad University,Dental Branch,Tehran, Iran

    Objectives: This study aimed to compare the frequency of dentinal micro-cracks following root canal preparation using ProTaper Universal and WaveOne rotary systems in straight and curved root canals.

    Methods: One hundred mesiobuccal straight and curved canals of mandibular molars with including criteria were divided into two control (n=10) and four experimental groups (n=20). All the canals were coronally flared using Gates- Glidden drills # 3 and 2 respectively. All the groups were instrumented in the full working length using ProTaper files (Sx, S1, S2, F1, F2), and Primary WaveOne (#25.08)(Dentsply, Maillefer, Ballaigues, Switzerland). All the roots were horizontally sectioned at 2, 4, and 6 mm from the apices, and then evaluated under a microscope at × 25 magnification to determine the presence of cracks. The number and types of cracks in straight and curved root canals were analyzed with Chi Square and Kruskal-Wallis tests. The significance level was set at P < 0.05.

    Results: The control groups showed no cracks. However, both rotary systems produced significantly less cracks compared to the specimens without any cracks. There was no significant difference between the two systems in the straight root canals (p>0.05). But in the curved root canals, ProTaper produced significantly more cracks (p

  • The effect of low level laser irradiation on speed of dentinal bridge formation in

    dental pulp exposure

    PRESENTER: Maziar Mir

    AUTHORS: M. Mir1, 2, M. Mazandarani1, M. Shabani1

    1. RWTH Aachen Conservative Dentistry

    Objectives: The aim of this study was to evaluate the effects of low level laser on dentinal bridge construction in hamsters after the creation of bur-induced pulp exposure.

    Methods: After administering inhalation anesthesia in hamsters, a pulp exposure (~0.5mm diameter) was made using a rotary machine with water spray in the lower anterior teeth. MTA dressing was used in the control teeth and MTA dressing combined with low level laser (1365 nm, 150 mw, 30 s) were applied in the experimental teeth. Dentinal bridge formation in both groups were imaged and the diameter of the dentinal bridges were measured using LSI(laser speckle imaging) with the aid of AMIRA software.

    Results: The application of MTA combined with low level laser showed faster dentinal bridge formation during the 72 hours after intervention than MTA alone.

    Conclusions: The Low-level laser irradiation accelerates dentinal bridge formation. However, further studies are recommended to evaluate the effectiveness of using low power laser for the rapid formation of dentinal bridges.

  • Triple Antibiotic Paste & Radicular Dentin; Pros and Cons

    PRESENTER: Ardavan Parhizkar

    AUTHORS: A. Parhizkar1, S. Asgary2, H. Nojeh - Dehyian1

    1. Dept. of Dental Bio-Materials, School of Dentistry - Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Objectives: To investigate the advantages and problems in the application of the recently focused Endodontic "Triple Antibiotic Paste", its possible effects on the radicular dentin, and the consequences when used as an intracanal medication in open - apex necrotic teeth with short roots and thin dentinal walls.

    Methods: After managing a proper tooth preparation in order to have complete access to the coronal pulp and radicular area, cleaning and shaping of the pulp chamber and root canal system were performed. To provide intracanal bleeding, an over-instrumentation was deemed necessary. For better disinfection of the canal and removal of the bacteria, "Triple Antibiotic Paste (TAP) was used. To use the antibiotic combination, Ciprofloxacin, Metronidazole, Minocycline were mixed (1:1:1) to a final concentration of 0.1-1.0 mg/ml and the tooth was followed periodically.

    Results: Nearly, all the open - apex necrotic teeth treated by TAP showed thickening of radicular walls, increased root length and closure of apical foramen. However, higher surface loss and roughness in the radicular dentin - in comparison with the untreated dentin with the medicament - were observed. The higher the concentration of TAP, the greater the extent of loss and roughness seen in the hard tissue. Also, significant reductions in the microhardness of the dentin following the use of TAP as the intracanal medication was noted.

    Conclusions: Recent studies and investigations regarding “Endodontic Regenerative Protocol (ERP)” and the diverse applications of TAP in the radicular space have revealed that, in a number of cases, ERP will end not only in the lengthening of the root canal but in the thickening of the dentinal walls; a phenomenon which can be deemed as a crucial advancement and unprecedented improvement in dealing with open – apex necrotic teeth, especially when TAP is compared with other medications. Nevertheless, next to these promising outcomes, there seems to be consequences for using TAP in the root canal area, some of which can turn out to affect the chemo - mechanical properties of the remaining dentin in the canal.

  • Desensitizing Efficacy of Diode Laser, Nd:YAG Laser and Dentin Bonding

    PRESENTER: Pegah Khazaei

    AUTHORS: P. Khazaei1, L. Ranjbar Omrani2, M. Hasani Tabatabaei2

    1. Tehran University of Medical Sciences

    Objectives: The aim of this study was to compare the clinical efficacy of the Diode laser, Nd:YAG laser and dentin bonding agent in the treatment of dentin hypersensitivity.

    Methods: This clinical trial was conducted on 135 teeth of 22 patients diagnosed with dentin hypersensitivity. Teeth were divided into three groups. In group 1, 45 teeth were irradiated for 1 minute with Diode laser (1W/cm2; λem =810nm). In group 2, 53 teeth were irradiated for 40 seconds with Nd:YAG laser (1W/cm2; λem =1064 nm). In group 3, 37 teeth were treated with CLEARFIL SE BOND. Laser Treatment was carried out in 3 sessions, at 7 days intervals during a 3 week period. Sensitivity was assessed by cold tests, measured using the criteria proposed by Uchida at baseline and at 1, 3 and at 6 months after treatment. Data analysis was performed using One Way Anova and T-Test.

    Results: The reduction of dentin hypersensitivity was observed in immediately post- treatment in each group. Statistically significant differences in the level of dentin hypersensitivity between groups were found only at 3 and 6 months after treatment (P

  • Root Taper Effect on Fracture Resistance

    PRESENTER: Amirreza Beglou

    AUTHORS: O. Dianat2, A. Beglou1, M. Sabeti4, M. Kazem3

    1. Dental School, Shahid Beheshti University of Medical Sciences

    Objectives: Endodontically treated teeth are susceptible to increased risk of fracture, mainly associated with loss of tooth structure, due to different steps of endodontic therapy including access cavity and root canal preparation. The aim of this study was to assess the effect of root tapering on the fracture resistance of root.

    Methods: In this in vitro study, 30 extracted single rooted premolars were decoronated using a diamond-coated bur, leaving the root 13 mm in length. The roots were assigned to 4%, 6% and 8% tapering groups (n = 10). Canals were prepared with rotary Twisted Files (SybronEndo, Orange, CA, USA) using 1.25% sodium hypochlorite. For root embedment, the roots were covered with additive silicone, for simulation of the periodontal ligament around the tooth, and placed in tubes filled with self-curing acryl. Roots were loaded to fracture in the Instron Universal Testing machine (Instron, Canton, MA) (1 mm/min), and the data was analyzed with One-way ANOVA and Tukey HSD tests.

    Results: In assessing the effect of root canal preparation taper on fracture resistance of teeth, 4% taper showed the highest (259.61 N) and 8% taper showed the lowest (168.43 N) fracture resistance values, and the value for the 6% taper was in between the two (251.82 N). No significant difference was observed between the 4% and 6% groups (P > 0.05); however, they both differed significantly from the 8% group (P = 0.001 and 0.003 respectively).

    Conclusions: Despite leading to superior canal debridement and decreasing the concerns regarding microbial removal of root canal walls, the results of the present study did not support the notion of using 8% tapering in endodontically treated teeth, as it had an adverse effect on tooth resistance compared to 4% and 6% tapering.

  • Comparative effect of "Light-Emitting-Diode" and "Low-level laser therapy" on root

    resorption

    PRESENTER: Samira Hosseini

    AUTHORS: S. hosseini1

    , M. Kamani1

    1. Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Objectives: The aim of this study was to compare the preventive and/or reparative effects of light emitting

    diode (LED) and low-level laser therapy (LLLT) on orthodontically induced inflammatory root resorption

    (OIIRR) in animals. Methods: An electronic search was performed using Google Scholar, PubMed and

    ScienceDirect based on PRISMA statement for systematic review and Meta-Analysis. Studies in animal in

    which LLLT or LED were applied to increase the dental movement were reviewed. The reviewed studies were

    subjected to meta-analysis for quantifying the differences. Two reviewers selected the articles. The resulting

    studies were analyzed according to the parameters used in the application of laser, LED and existing changes

    clinically and histopathologically.

    Results: The researches retrieved 26 unique citations from which 5 remained after considering the abstracts.

    Evidence suggests that the comprehensive orthodontic treatment causes increased root resorption (RR).

    According to researched data LED therapy improved periodontal tissue repair and decreased inflammation

    and RR after the application of orthodontic force .Also, LED-mediated photobiomodulation method has the

    potential of accelerating tooth movement and inhibitory effects on OIIRR. The reparative and resorptive

    processes were increased by LLLT applied during orthodontic force load. LLLT has significant reparative

    effects on OIIRR while it is not possible to say that it definitely has a preventive effect. Moreover, LLLT can

    accelerate induced tooth movement by increasing the activity of osteoclastic cells and reduction in RR

    lacunaes. The laser beam irradiation in combination with alloplastic materials used for socket preservation

    could reduce the degree of RR. LED therapy has certain advantages over LLLT, such as the low cost, large

    application areas, and no generated heat.

    Conclusions: All data suggested that LED decreases the OIIRR while there is conflict about the effect of LLLT

    on OIIRR and more researches particularly clinical attachments are needed.

  • Oral Health 1

    Oral Health Status and Behaviors of pregnant mother

    PRESENTER: Marzieh Deghatipour

    AUTHORS: M. Deghatipour1

    , Z. Ghorbani2

    , R. taheri3

    , F. ehdayivand4

    1. Community Oral Health Department, School of Dentistry, Shahid Beheshti University of Medical Sciences

    Objectives: The aim of this study was to assess the oral health status and associated factors in pregnant

    women.

    Methods: A cross-sectional study was conducted amongst pregnant women in the second and third of

    pregnant women in Varamin, Iran. The participants compromised 313pregnant women whose oral health

    was examined in the study. Demographic, socioeconomic status, and health behavior data were determined

    by using a standard questionnaire. Oral health examination included studying pocket depth, bleeding on

    probing (BOP) and dental caries. Data analysis was done using SPSS (version 21) and STATA (SE 11).

    Regression analysis was used to study the association between demographic, oral health behaviors indicators

    and BOP, DMFT, D, M, F indices.

    Results: The mean age of the 313 pregnant women was 27.7(sd=5.7, range=15-44 years). More than half of

    the participants (61.7%) brush their teeth daily, but only 38.3% of mothers had daily flossing habit. Mean (sd)

    of DMFT, D, M, F were 9.97(5.18), 6.54(4.37), 2.18(2.64), 1.25(2.34), respectively. Approximately 70% of

    women had BOP. A significant relationship between BOP during pregnancy and using dental floss was

    observed (P

  • The implications of a study on food, drink and snacks advertisements in El Salvador

    for the developing countries

    PRESENTER: Baharak Amanzadeh

    AUTHORS: B. Amanzadeh1

    1. Preventive and Restorative Dentistry, University of California San Francisco, USA

    Objectives: Analyse the root causes of the "nutrition transition" and the role of globalization and increased marketing of nonnutrotious foods and beverages and its impact on the health of the populations in developing countries. Describe the strategies and messages used to promote consumption of highly processed, commercialized products. Methods: Digital photographs of billboard and wall advertisements recorded a convenience sample of 100 advertisements, including 53 from rural areas and 47 from urban areas in El Salvador. Advertisements were coded for location, type of product, visual details, placement and context. Qualitative methods were used to identify common themes used to appeal to consumers. Results: Advertisements depicted "modern" fast foods, processed snacks and sugary beverages. Overall, the most prominent themes were: Cheap Price, Fast, Large Size, and Modern. Other themes used frequently in combination with these were Refreshment, Sports/Nationalism, Sex and Gender Roles, Fun/Happy Feelings, Family, Friendship and Community, and Health. In rural areas, beverage and snack food ads with the themes of cheap price, fast, and large size tended to predominate; in urban areas, ads for fast food restaurants and the theme of modernity tended to be more prominent. Conclusions: Global food and beverage industries must be held accountable for the adverse public health effects of their products, especially in low-middle income countries where there are fewer resources to prevent and treat the health consequences. In addition, public health and governmental authorities should learn from the advertising strategies to promote social marketing of public health messages, and enact and enforce regulations to limit the advertisement and sale of unhealthy products, particularly for children in and around schools. This will create healthier social norms and environments for the entire population. Even though this study has been done in El Salvador, but the results and conclusion can be used to undrestand the similarities in other developing countries and to inform effective policies and practices.

  • Agent Based Modeling: Effect of friendship network on dental brushing behavior of

    high school students

    PRESENTER: Maryam Sadeghipour

    AUTHORS: M. Sadeghipour1

    1. Community Oral Health Department, School of Dentistry, SBMU

    Objectives: Given the state of oral diseases epidemics, there is a great need for innovative and more cost-

    effective interventions. Developing a model for dynamics of dental health behavior through student

    friendship networks in a high school setting was the main objective of this investigation.

    Methods: By using a standard questionnaire, the level of dental brushing frequency was assessed twice with

    5 months interval, among 201 adolescent girls in a high school setting. Logistic Regression analysis was used

    to evaluate the correlation among individuals’ dental health behavior in their social network. Agent Based

    Modeling was used to model the dynamics of dental brushing frequency level within the student friendship

    network. Three different educational scenarios were compared using simulation results to identify some

    aspects of policy implication of the model

    Results: A significant correlation on dental brushing habits was detected among groups of friends. This correlation defuses through the network in 5 months period. Furthermore, it was identified that, the level of brushing was improved among the target student population within the study period. It was identified that, there was a significant correlation between nodes’ with more popularity, within the social network as well as brushing level. It was therefore suggested that, the improvement is partially due to the more popularity of individuals with better tooth brushing.

    Conclusions: The Agent Based Modeling proved to be a useful means of choosing the most cost- effective oral health promotion programs by policy makers after testing different potential oral health promotion scenarios

  • The impact of two educational interventions regarding dental trauma on knowledge

    of primary school teachers in Arak, Iran.

    PRESENTER: Mahdia Gholami

    AUTHORS: S. Razeghi1

    , M. Mashayekh3

    , M. Gholami2

    2.

    Community Oral Health, Tehran University of Medical Sciences

    Objectives: To compare the impact of two educational interventions about dental trauma on knowledge of

    primary school teachers in Arak.

    Methods: We conducted an interventional study among primary school teachers in Arak in 2015. An

    anonymous questionnaire including demographic characteristics and knowledge regarding emergency

    management of TDIs was developed. At baseline, the data was collected by the questionnaire on voluntary

    basis. Afterward the participants were randomly divided into two interventional groups including lecture and

    pamphlet. In the lecture group, the teachers participated in a 45-minute meeting that was conducted by one

    of the researchers. In the pamphlet group, the pamphlets, having the same content of the lecture, were

    distributed among the participants. One month and six months after the intervention, the same

    questionnaires were filled out by the respondents. The score of knowledge with range of 0 to 10 and its

    changes were calculated and were evaluated using statistical analyses in order to examine the impact of the

    interventions.

    Results: In all, 154 individuals participated in the pamphlet group and 138 individuals responded in the

    lecture group. Among demographic variables, the baseline knowledge was significantly associated with the

    level of education (p

  • Patients' non-clinical satisfaction from dental visit in Tehran, Iran

    PRESENTER: Zahra Ghorbani

    AUTHORS: Z. Ghorbani1

    , M. Pakkhesal2

    , M. Namdari2

    1. Community Oral Health Department, School of Dentistry, SBMU

    Objectives: The aim of this study was study the non-clinical satisfaction with dental care among adults in

    Tehran, Iran.

    Methods: Self-report data were obtained from the 2010 dental telephone interview survey. A stratified

    random sample of 1,100 adults aged 18–84 years living in Tehran was studied (response rate=73%). The

    patients who had visited a dentist in the previous year determined the degree of their satisfaction, ranging

    between 0-10, regarding the reception's and dentists respectful behavior, the dental clinic facilities and

    cleanness, the waiting time, and the oral hygiene instructions received in their last dental visit.

    Socioeconomic status (SES) was measured by both education and asset index. Satisfaction scores were highly

    skewed with approximately 50% of participants ranking 10 (fully satisfied). Unadjusted and adjusted tobit

    models were used to study the association between SES and patients' satisfaction. The Iran Centre for Dental

    Research granted ethical approval for the original study.

    Results: From the 1,100 participants, 597 (53.8%) had visited a dentist in the previous 12 months. Higher

    satisfaction in all aspects was reported among those in the wealthiest quintile and those seeking care from

    private dental clinics. Satisfaction scores were not different among age, gender and education groups.

    Conclusions: Non-clinical satisfaction with dental care was associated with wealth but not with education.

    Private dental clinics provided patients with more satisfaction of non-clinical aspects of dental care.

  • Epidemiologic survey of traumatic dental injuries among Iranian children: INOHS-

    2012

    PRESENTER: Mona Azim

    AUTHORS: Azim M1, Ghasemianpour M 2, Khoshnevisan MH 2,3

    1 Dental Resident, Department of Periodontology. School of Dentistry, Shahid Beheshti University of Medical Sciences,

    Tehran, Iran. 2 Preventive Dentistry Research Center, Dental Research Institute, School of Dentistry, Shahid Beheshti

    University of Medical Sciences, Tehran, Iran. 3 Associate Professor of Dental Public Health; Chair, Community Oral health

    Department, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    Objectivees: Dental traumas are common among children and adolescents constituting one-fifth of total

    trauma among children in many societies and considered a public health problems. A large percentage of

    children may experience some type of injury to a tooth that occurs in accidents or sports-related injuries

    during childhood, many of which are preventable. The aim of this study was to determine the prevalence of

    traumatic dental injuries in 3 age groups of Iranian children.

    Methods: Stratified random sampling method was used to recruite samples according to WHO

    recommended survey methodology (2013). Total of 26407 children in 3 WHO recommended age groups were

    recruited to this study from all provinces in Iran. The children were screened using WHO criteria. Calibration

    of examiners and recorder were conducted in order to improve the quality of data. Statistical analysis was

    conductd after data clean up and quality check.

    Results: The results showed that, overall prevalence was 4.1%, with 5.4% in boys and 3.1% in girls. Group

    comparison showed the highest prevalence among 15 year old agegroup (6%). When comparing provinces,

    Kohkiloyeh and Boyrahmad demonstrated the highest prevalence of disease in 12 and 15 year old agegroups.

    The higher the parental education level, the lower the prevalence of dental trauma (father: p=0.06; mother:

    p

  • Standard questionnaire for electronic oral health information system analysis in Iran

    PRESENTER: Homa Fathi

    AUTHORS: H. Fathi2

    , E. Maserat3

    , F. Boroumand4

    , M. Nouri1

    2. School of Dentistry, SBMU

    Objectives: Conducting oral health information system analysis and need engineering before developing

    information systems has been of little concern in Iranian dental schools. In this research we designed a

    questionnaire for analysis of available systems and tested its validity and reliability.

    Methods: In this descriptive study a questionnaire was designed to analyze clinical and educational software

    in Iranian dental schools. Articles were extracted from different databases including Pub Med, Science Direct,

    Iran Medex, EMBASE and Scopus. Relative key words including “electronic health system”, “electronic health

    record”, “analysis”, “barriers”, ”priorities” and “infrastructures” were used . Primary questionnaire comprised

    of 72 questions in 9 aspects including: Prioritizing administrational and organizational infrastructures, barriers

    to administrational and organizational infrastructures, prioritizing educational infrastructure, barriers to

    educational infrastructure, prioritizing technical infrastructure, barriers to technical infrastructure, prioritizing

    security, privacy and legal infrastructures, barriers to security, privacy and legal infrastructures, prioritizing

    infrastructure standards. Questionnaire was surveyed by 20 experts in these 9 fields. Reliability of

    questionnaire was estimated by Cronbach's alpha test.

    Results: Validity and reliability of the questionnaire was estimated and confirmed through experts’ opinions

    and Cronbach's alpha test. All the questions with final reliability scores of less than 0.55 were dismissed. This

    led to dismissal of 12 questions.

    Conclusions: A 60 item standard questionnaire was developed. This questionnaire could be used as an

    appropriate tool for analyzing clinical and educational software of dental faculties in Iran

  • Craniofacial biology & stem cells

    Local and systemic administration of mesenchymal stem cells in regeneration of mandibular defects: an experimental study

    PRESENTER: Pantea Nazeman

    AUTHORS: A. Khojasteh2

    , M. Dehghan3

    , S. Motamedian4

    , P. Nazeman1

    , M.Alikhasi5

    , M. Soleimani6

    , S.

    Mohajeri3

    1. Dental Research Center, School of Dentistry, SBMU

    Objective: Mesenchymal stem cells (MSCs) have been utilized as an aid in regeneration of bone defects

    however due to the poor homing ability via systemic injection, local administration and genetic manipulation

    have been used more widely. The present study aimed to compare local and systemic application of MSCs in

    regeneration of bone defects.

    Methods: Sixty Wistar male rats were used in this study. Circular 5×5 mm bone defects were created in the

    angle of the mandibles. Autogenous bone marrow mesenchymal stem cells (BMMSCs) were obtained and

    culture expanded. The cells were labeled by red fluorescent for detection of the cells in the healed bone. The

    rats were randomly treated in four groups; 1. β-TCP scaffold seeded with MSC (β-TCP+MSC), 2. Intravenous

    MSC injection with β-TCP scaffold in the defect (MSC), 3. β-TCP without cell therapy (β-TCP) and 4. Control

    defects which were left empty. The rats were euthanized after 8 weeks. New bone formation (BF) were

    investigated by hematoxylin and eosin staining on decalcified 5 micrometer sections.

    Results: Localized cell therapy (β-TCP+MSC group) showed the highest healing rate (BF=%54.05±2.39)

    followed by MSC systemic injection (BF=%22.69±3.87). Immunofluourescent analysis demonstrated presence

    of MSCs at the defects in MSC and β-TCP+MSC groups.

    Conclusions: It is demonstrated that local application of the MSCs with synthetic scaffold had better results

    than intravenous administration of MSCs in treatment of rat mandibular bone defects.

  • Growth and Characterization of Dental Pulp's Stem Cells of Deciduous Versus

    Permanent Teeth, an in vitro study

    PRESENTER: Hamidreza Moslemi

    AUTHORS: S. Vahabi1

    , M. Baghban eslami3

    , M. shariati4

    , H. Nazarian4

    , H.Moslemi2

    1. School of Dentistry, SBMU

    Objectives: Presence of stem cells within the pulp tissue has been indicated in both temporary and

    permanent human teeth so far. In the present study, these stem cells were compared in terms of their

    growth kinetics and culture requirements.

    Methods: Stem cells within the pulp of the deciduous incisor (temporary tooth) and Adult third molar

    (wisdom tooth) were isolated, culture-expanded and characterized according to the standard protocol. Then

    the potentials of the proliferation of the cells were compared using multiple cell growth indices as Population

    doubling time (PDT), colonogenic activity and growth curve. Furthermore, the cultures of both cells were

    optimized for maximal proliferation. The alpha error was set at 0.05 for all tests.

    Results: Stem cells of either pulp tissue appeared as fibroblastic cells capable of differentiating into

    osteoblastic, chondrocytic, odontoblastic and adipocytic cell lineages. Stem cells from incisor tooth expressed

    neurogenic markers of ßIII Tubulin and Tau just in contrast of molar stem cells. Based on in vitro growth data,

    the cells from third molar tended to have a lower PDT value (20.79, sd=2.8 vs. 25.55, sd=2.9 hours), higher

    colonogenic activity and better growth curve than those from the deciduous incisor (P

  • Different methods of isolating periodontal ligament stem cells and CD markers

    PRESENTER: Zahra Aghamohammadi

    1) AUTHORS: Z. Aghamohammadi1

    , F. S. Tabatabaei1

    1. Dental Bio Material , Shahid Beheshty University of Medical Sciences

    Objectives: Human periodontal ligament stem cells (PDLSCs) are a unique population of mesenchymal stem

    cells (MSCs) which possess an immense capacity to generate cementum- and periodontal ligament-like

    structures. Herein we summarize the latest findings regarding the methods of isolation and CD markers of

    PDLSCs.

    Methods: A review of the literature was performed using PubMed, using keywords like “PDL stem cells”,

    “isolation”, “CD markers”. The search was limited to articles published over the last 10 years in English.

    Results: In 2004 the first report on isolation and identification of stem cells in PDL was published. Since then,

    Improvements have been made in isolation and culture of PDLSCs, however tooth extraction for PDLSC

    isolation is an obstacle for using these cells in patients who do not need tooth extraction. In vitro, PDLSCs

    may be isolated using CD markers. PDLSCs express CD146, STRO-1, CD105, CD29, CD44, CD133, CD106,

    CD166, CD90, CD73, SCX (Scleraxis/tendon-specific marker), but lack the expression of CD45, CD34, CD14,

    CD11b, CD79a, or CD19 and HLA class II.

    Conclusions: PDLSCs may hold a promise as the very basis for practical cellular-based treatment in

    periodontal regeneration.

  • Establishment and characterization of human oral squamous cell carcinoma cell line

    PRESENTER: Sepanta Hosseinpour

    AUTHORS: F. Mashhadiabbas 1

    , Yousef Janbaz1, Hamid Nazarian2, Hasan Mirmohammad Sadeghi3,

    Fereydoun Pourdanesh3, S. Hosseinpour4

    1. Oral and Maxillofacial Pathology Department, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    2. Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    3. Oral and maxillofacial Surgery Department, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    4. Student’ Research Office, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    Objectives: Nowadays, cell culture and cell line establishment is one of the main parts of laboratory research

    in cancer centers. Human oral squamous cell carcinoma is one of the most common types of cancer in head

    and neck area and unfortunately there is no improvement in survival rate of patients in the past four

    decades. We must use cancer cell line to study tumor behavior in laboratory condition to directly link it to

    clinical manifestation of cancer.

    Methods: In this research, three fresh tissue of human oral squamous cell carcinoma were obtained with

    excisional biopsy and then were delivered and cultured in Shahid Beheshti dental research center. We used

    flow cytometry analysis for CD34 and E-cadherin for evaluating cells and extracted the flow cytometry data's

    with Flowjow software which then analyzed by T-test.

    Results: Flow cytometry analysis showed significant positivity for epithelial marker for each specimen. In

    comparison with IgG1 isotype, p-value for CD34 specimen is 0.05 while for E-cadherin specimen the p-value is

    0.0005. All of three cultured cell lines demonstrated significant positivity for epithelial marker.

    Conclusions: This study is the baseline for other cancer research like detecting other markers and methods

    for cell line establishment, animal's cell line studying, and designing new clinical surgical procedures.

  • The effect of Emdogain and Simvastatin on periodontal ligament stem cells

    differentiation to osteoblasts: An in vitro study

    PRESENTER: Masih Lazar

    AUTHORS : B. Houshmand2

    , I. Amiri3

    , M. Hajilooi4

    , M. Dalband5

    , S. Soheilifar6

    ,M. Lazar1

    1. Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    Objectives: Regeneration of periodontium is one of the main goals of periodontal treatment. This may be

    achieved by differentiation of stem cells to periodontal tissue cells.This study sought to assess the

    differentiation of human periodontal ligament stem cells (PDLSCs) cultured in osteogenic medium

    supplemented with Emdogain or Simvastatin.

    Methods: After teeth extraction, the PDL attached to the middle third of the root surface was removed. Cells

    were expanded in culture medium and used for osteogenic differentiation and added to the test materials

    (different combinations of the basic medium, dexamethasone [DEX], Simvastatin and Emdogain). Osteogenic

    differentiation was evaluated using Alizarin Red staining (ARS), alkaline phosphatase (ALP) activity and

    calcium content tests.Statistical analysis was performed using SPSS version 17 software. Deliberation was

    done with 6 × 3 factorial (six groups × three periods). Then, the data were submitted to ANOVA, and the

    differences between the groups were compared using Tukey post-hoc test

    Results: Quantitative analysis of ARS demonstrated that the frequency of mineralized nodule formation was

    the highest in the enamel matrix protein derivatives (EMD) + DEX group. The highest ALP activity on day 7

    was in DEX + Simvastatin group. Calcium content was the lowest in the control group and the highest in EMD

    + DEX group at all tested time points

    Conclusions: This study showed that 100 μg/ml Emdogain had a significant effect on osteogenic

    differentiation of human PDLSCs to osteoblasts and 10−8

    M Simvastatin had an effect comparable to that of

    DEX.

  • Dental material 1

    The effect of post material ( Ni-Cr and NPG ) and cement type on the fracture

    strength of endodontically treated teeth and restored with cas post-core

    PRESENTER: Alireza Hadi

    AUTHORS: Alireza Hadi1

    1. Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    Objectives: Today, NPG (Non Precious Gold ) post casting alloys which have a very similar MOE to dentin ,

    have been introduced to dental market. It is claimed that it is possible to increas fracture strength of

    endodontically treated teeth, by using NPG alloys. We decided to evaluate the effect of casting alloys with

    similar MOE to dentin on the fracture strength of endodontically treated teeth.

    Methods: Materials and methodes :This is an invitro-experimental study on 40intact extracted mandibular

    one-canal pre molares.the teeth were decoronated and endodontically treathed , then post space were

    preparated.specimens were randomely devided to 4 groups :groupA: Ni-Cr alloy +zinc phosphate cement ,

    group B: : Ni-Cr alloy +Panavia F2 cement, group C:NPG alloy +zinc phosphate cement, group D:NPG alloy

    +Panavia F2 cement. fracture strength of the specimens were tested in Universal testing machin and ftacture

    patterns were observed with eye and recorded.

    Results: according to the resultes ,there was a significant fracture stength differece between also the two

    alloy type (P

  • Microshear Bond Strength of Universal Adhesives to Dentin

    PRESENTER: Niloofar Kianvashrad

    AUTHORS: N. Kianvashrad1

    1. Cosmetic and Operative Dentistry , Semnan University of Medical Science

    Objectives: Durability of adhesive bonds is an important factor in success of adhesive restorations. Micro-

    shear bond strength test is extensively used for assessment of bond strength. This study aimed to compare

    the microshear bond strength of three universal adhesives to dentin at 24 hours and six and 12 months.

    Methods: This in vitro, experimental study was conducted on 144 permanent premolar teeth. Their crowns

    were sectioned into 2mm-thick slices. The samples were divided into three groups (n=48) for testing at 24

    hours and six and 12 months. Each group was divided into three subgroups for application of All-Bond

    Universal (ABU), Single Bond Universal (SBU) and Peak Universal Bond (PUB) adhesives. Composite cylinders

    were fabricated on each sample and light cured. The samples were subjected to microshear bond strength

    test and the mode of failure was determined under a stereomicroscope. The data were analyzed using two-

    way ANOVA and Tukey’s post-hoc test.

    Results: The mean microshear bond strength at 24 hours and six and 12 months was 56.84, 44.60 and

    28.46MPa for SBU, 38.69, 29.74 and 11.32MPa for ABU, and 28.83, 20.32 and 11.65MPa for PUB,

    respectively. Mixed fracture had the highest frequency in all groups. The frequency of mixed fractures

    decreased while the frequency of adhesive fractures increased over time.

    Conclusions: Bond strength of universal adhesives decreases over time. The bond strength of ABU and SBU

    was higher than that of PUB.

  • Effects of Anbarnesa solution on the incisional wound healing in male rats

    PRESENTER: Setareh Sohrabi

    AUTHORS: H. Shafiee 2

    , J. B. Taheri3

    , K. Joharchi4

    , S. Anaraki 5

    , F. Mashhadiabbas1

    2. Shahid Beheshti University of Medical Sciences, Tehran, Iran.

    Objectives: The purpose of this study was to evaluate the effects of Anbarnesa solution on healing of

    incisional wound in male rats.

    Methods: In the main study, 16 rats weighing 180-250 g were selected and sacrificed at 14 and 21 days of

    treatment with Anbarnesa (ANNAS1) or propylene glycol.Two full-thickness wounds 5mm in diameter were

    created on the back of the neck one served as the case and the other as the control group. The rats were

    divided into four groups of one. ANNAS1 was applied to the case and propylene glycol to the control wounds

    daily. Specimens were taken and stained and the slides were histologically analyzed under a light microscope.

    On each section, three areas were randomly chosen and number of myofibroblasts was counted at deep and

    superficial areas of the wounds. Data were analyzed using SPSS version 18.

    Results: Based on the results, both 14 and 21 days, number of myofibroblasts on the wound surface in

    ANNAS1 group was significantly less than that in the control groups. No significant difference was noted in

    terms of the number of myofibroblasts in the superficial compared to deep areas of wounds treated with

    ANNAS1. At 14 and 21 days, the mean number of myofibroblasts in both deep and superficial areas of

    wounds in ANNAS1 group was significantly lower than that in the control/control wounds.

    Conclusions: The Anbarnesa solution had positive effects on decreasing scar formation in the process of

    wound healing

  • Evaluation of Drug Adsorption on the synthesized silica aerogel

    PRESENTER: Manijeh Mohammadian

    AUTHORS: M. Mohammadian1

    , T. S. jafarzadeh kashi1

    , M. Erfan2

    , M. Tahriri4

    , F. Pashaei Sorbaghi3

    , S.

    Heidari1

    1. Tehran University of Medical Science, Tehran, Iran

    Objectives: Silica based materials are widely used in medical fields. Silica aerogels are new biomaterials with

    special properties for applying in tissue engineering as drug carriers. Recent studies have shown that the

    silica aerogels are appropriate biomaterials to be used in drug delivery systems due to their excellent

    characteristics including low density, high porosity and surface area and special nanostructure. In this work,

    the adsorption of ketoprofen on the synthesized silica aerogel was evaluated.

    Methods: In this study, silica gel was prepared by sol-gel method using tetramethyl orthosilicate (TMOS) as a

    precursor. Supercritical carbon dioxide was used for drying process and drug (Ketoprofen) loading in

    synthesized aerogel through the adsorption from liquid phase. The characterization of the silica aerogel was

    performed by XRD (X- ray diffraction), SEM (scanning electron microscope) and BET (Brunauer–Emmett–

    Teller) analysis. The cytotoxicity was evaluated by MTT assay. Drug loading was investigated by UV–visible

    absorbance spectroscopy and FTIR (fourier transform infrared) spectroscopy.

    Results: The silica aerogel had a specific surface area of 500 m2/g. XRD showed amorphous and crystalline

    structures for silica aerogel and Ketoprofen, respectively. The nano-sized particles of silica and “string of

    pearls” morphology were observed by SEM. Drug loading was confirmed by UV- visible and FTIR

    spectroscopy. MTT assay proved high biocompatibility for silica aerogel.

    Conclusions: The porous structure, large surface area and high affinity of an anti-inflammatory drug such as

    Ketoprofen to silica aerogel, makes this material a good candidate for drug delivery systems.

  • Fracture Toughness of Self-adhesive Composite to Dentin using Different Pretreatments

    PRESENTER: Mohammad-ali Keshvad

    AUTHORS: T. Hooshmand1

    , M. Behroozibakhsh1

    , M. keshvad2

    , S. Davaie1

    2. Tehran University of Medical Science, Tehran, Iran

    Objectives: To evaluate the effect of different surface pretreatments on the interfacial fracture toughness of

    a self adhesive flowable composite to dentin.

    Methods: Fifty-three human molars were embebded in acrylic resins and sectioned to expose the underlying

    dentin. Bonding area of 4 mm in diameter with a 90 degree chevron shape was produced on a PTFE tape

    using a custom- made punch and then the specimens were divided into 4 subgroups based on their surface

    treatments: Group 1: control (no surface pretreatment), Group 2: self-etching adhesive, Group 3:

    chlorohexidine gluconate 2%, Group 4: oxalate dentin desensitizer. After surface treatments, the self-

    adhesive flowable composite was built up with the height of 10 mm by a cylindrical transparent tube.

    Specimens were incubated in distilled water and then thermocycled for 3500 cycles. Specimens were then

    submitted to the force at cross-head speed of 1 mm\min using universal testing machine. The modes of

    failure were evaluated by a stereomicroscope. Data were analyzed using Chi-square followed by Kruskal–

    Wallis test.

    Results: Statstical analysis revealed that the interfacial fracture toughness for the self etching adhesive was

    siginficantly higher than that of other groups (p0.05). Adhesive fracture was the most prevelant mode of failure for

    all groups.

    Conclusions: The self-adhesive flowable composite with no bonding system had lower bonding efficacy when

    compared with the combination use of a self-etching adhesive.

  • Poster

    presentation

  • Session 1

    Oral Health Literacy Among Adults in Kerman

    PRESENTER: Mahsa MalekMohammadi

    AUTHORS: M. MalekMohammadi1

    , T. Malekmohammadi2

    1. Shahid Beheshti University of Medical Scineces, Tehran, Iran

    Objectives: promoting oral health in 21st century needs a variety of abilities and competencies which one of

    them is titled oral health literacy. This competency includes interaction with culture and society, educational

    system, and health system to access and appraise information as a basis for appropriate oral health decisions.

    The present studywas aimed to assess oral health literacy level and its related factors among adult patients

    visiting Kerman dental school.

    Methods: This cross sectional study was conducted in Kerman Dental School clinic, among first time adult

    visitors. Individuals were selected randomly among volunteers who signedconsent form during the study

    period. Background information, socio-economic status, self-reported oral health and behavior, oral health

    information resources, and oral health literacy level were acquired by OHL-AQ. In addition to descriptive

    statistics, several analyzes including chi- square tests, ANOVA and independent T-Test served for statistical

    evaluation of study data.

    Results: Study participants including 264 adults were consisted of 72.3% women. Most had a diploma with a

    mean age of 37±8 years old. About half of the participants brushed daily. The most common oral health

    information sources which was used by 44.4% of respondents were dentists. Mean oral health literacy score

    was 12.07(out of 17) and of the whole participants 62.5% had adequate oral health literacy level. There was a

    significant relationship between oral health literacy scores with gender, high level of education and oral

    health behavior.

    Conclusions: The study participants had a good level of oral health literacy which can be correlated with their

    educational status and oral health information sources. An oral health educational program for less educated

    people is recommended. oral health literacy score was 12.07(out of 17) and of the whole participants 62.5%

    had adequate oral health literacy level. There was a significant relationship between oral health literacy

    scores with gender, high level of education and oral health behavior.

  • Dental caries prevalence and associated factors in Iranian three years old children- a

    cross sectional study

    PRESENTER: Mitra Ghazizadeh Ahsaie

    AUTHORS: M. Ghazizadeh Ahsaie1

    , F. Ehdaivand4

    , M. Deghatipour3

    , M.Eghbal1

    , Z. Ghorbani2

    1. Shahid Beheshti University of Medical Scineces, Tehran, Iran

    Objectives: The aim of this paper was to study dental caries experience and associated factors in children

    aged 3 years old living in Varamin, Iran.

    Methods: eight hundred and fifteen [zg1] three year old children were recalled randomly through the records

    existing in healthcare centers of Varamin, Iran. Two hundred and three mothers were also examined to study

    the relationship between mothers’ and children oral health. Dental examinations were performed by

    calibrated senior dental students using decayed missed filled teeth (dmft/DMFT) indices. Demographic and

    oral-healthcare behavior data were gathered using a standard questionnaire.

    Results: The mean dmft was 2.69 (sd=3.492, range 0-19). The mean dmft in girls was 2.54

    (Std.Deviation=3.39), and the mean dmft in boys was 2.86 (Std. Deviation=3.59[zg1] ). No significant

    difference was seen between the dmft of two genders. No significant difference was seen in dental care

    behavior such as frequency of eating sweets, brushing, flossing and dental visit between the two gender

    (p>0.05). A positive correlation was detected between mother’s DMFT and child’s dmft ( r = 0.27, p

  • Social Capital as Facilitator of Dental Visit During Pregnancy

    PRESENTER: Hoda Bahramian

    AUTHORS: H. Bahramian1

    , S. Z. Mohebbi1

    , M. R. Khami1

    1. Tehran University of Medical Scineces, Tehran, Iran

    Objectives: Time constraints and crowded family sometimes prevent women from attending dental clinics.

    Social capital may improve pregnant women oral health by a positive impact on pattern of their attending

    dental services. This study aimed to explore pregnant women’ perspectives on dental attendance during

    pregnancy and role of social capital to facilitate it.

    Methods: In this qualitative study, ten in-depth individual semi-structured interviews and two organized

    focus group discussions were conducted by a dentist as moderator and a midwife as facilitator. Participants

    (n=22) were selected purposefully from those attending public health centers, in two socioeconomically

    different districts of Tehran, Iran, for their routine prenatal checkups, in February 2015. A topic guide was

    used on demographic and pregnancy related questions, their history of attending dental clinics and its social

    capital barriers. By saturation of data, the interviews were audiotaped and transcribed with the permission of

    the participants and then coded for content analysis using MAXQDA10 software.

    Results: The mean age of the pregnant women were 30.4 ± 7.5 years with a mean gestational stage of 25.3 ±

    6.4 weeks. Thirty-two percent of pregnant women had academic education and half of them were employed.

    Of 350 extracted codes, the major findings as reasons of low dental attendance among those pregnant

    women who were aware about importance of dental visit during pregnancy and could afford dental expenses

    were categorized within three main themes of difficulty to arrange time off from work, having large family

    size and household responsibilities, and problem of finding care for elder children when seeking dental care.

    Conclusions: This study emphasized the role of social and family support to manage time and family

    conditions of pregnant women for making regular dental visits possible during pregnancy.

  • Iranian mothers’ views regarding causes of halitosis: a Qualitative Study

    PRESENTER: Zahra Momeni

    AUTHORS: Z. Momeni1

    , K. Sargeran2

    , R. Yazdani2

    1. Community Oral Health Department, School of Dentistry, Tehran University of Medical Sciences (TUMS)

    Objectives: Halitosis, an unpleasant breath/ mouth odor, is a very common condition in general population

    and described as a serious social handicap. The aim of the present study was to explore Iranian mothers’

    perceptions about the causes of halitosis.

    Methods: In the present qualitative study, participants were mothers (n = 58) who had a primary school child

    in Tehran, 2015. They were selected purposively from eight primary schools in different districts of Tehran,

    the capital of Iran. Ten focus groups and semi-structured interviews were used to explore their views on

    halitosis and its causes. Interviews were audio-recorded, transcribed verbatim and analyzed using a

    conventional content analysis method.

    Results: The majority of the participants mentioned role of poor oral hygiene, malnutrition and poor

    digestion as well as intra-oral diseases such as dental caries and periodontal diseases, as etiologic factors of

    halitosis. Also, they recommended oral hygiene instructions such as toothbrushing, flossing, cleaning the

    tongue and using mouth rinse for malodor control. Mothers highlighted negative effects of oral malodor on

    children’s social interactions.

    Conclusions: The present findings affirm acceptable knowledge of Iranian mothers regarding halitosis.

    Malodor influences social interactions and consequently, creates detachments among people. Management

    of halitosis has the potential to improve social interactions.

  • Dentists knowledge of antibiotic prophylaxis in Bandar Abbas city

    PRESENTER: Sajad Ansari Fard

    AUTHORS: S. Sadr1

    , S. Ansari Fard2

    , M. Vakilinezhad1

    1. Hormozgan University of Medical Sciences

    Objectives: The aim of this study was to determine Bandar Abbas's dentist’s knowledge of antibiotics

    prophylaxis in 2015. This descriptive- analytic cross-sectional study involved dentists in Bandar Abbas in 2015.

    Methods: All dentists 137 in the city were invited to take part in the study. A piloted questionnaires with 53

    questions on the topics of the need for antibiotic prophylaxis and prophylaxis regimes and an explanatory

    note were handed out to the dentists and collected in the same day. Multi- variant regression was used for

    data analysis

    Results: One hundred and twenty six dentists completed the questionnaire of whom 69 (53%) were men and

    57 (47%) were women. The mean age of participants was 44.9 years. Mean time spent from graduation as a

    dentist was 11 years. Mean score for correct answers to questions on when and why to provide antibiotic

    prophylaxis was 72.9 (of a maximum score 104). Sixty three dentists (50%) scored less than 63 (50%).

    Conclusions: In the sample of dentists, who replied to the questionnaire, 50% showed poor knowledge of

    when and why to prescribe prophylactic antibiotics. If this is also true for other dentists in Iran there is a need

    for a national educational program on this topic.

  • Assessing the questionnaires on perceived oral health care need, a systematic

    review

    PRESENTER: Zahra Yaghoubi

    AUTHOR: Zahra Yaghoubi1

    1. Dental public health, Dental school of Kerman university of medical sciences

    Objectives: Perception of need for oral health care plays a key role in creating motivation and demand for

    utilization of oral health care services. Also, while the lack of resources, people with perceived needs to oral

    health care, due to higher profit potential of services, will be on higher priority for services. The aim of this

    study was to undertake a systematic review of the existing literature about questionnaires used for analyzing

    the perceived oral health care needs.

    Methods: The search was conducted in PubMed, ISI and Scopus databases on March 2016. Papers were

    potentially suitable for inclusion which were questionnaire-base and aimed to determine perceived need for

    any types of oral health care and dental treatment. After determining related papers, each paper data was

    extracted and all the questions and responses were reviewed.

    Results: Of 7069 records found, 192 questionnaire-base papers were included in the review. 94 papers were

    related to overall evaluation of oral health care need, which did not ask the need for types of oral health care

    service. 66 papers studied need for a specified dental service, and 32 records the types of oral health care

    service were asked in open or multiple choices question. There was not comprehensive and standard

    questionnaires which covers all the common types of oral health care services.

    Conclusions: Differences in the available questionnaires showed despite the importance and necessity of

    considering perception of needs for oral health care, there is a lack of the comprehensive and standard

    questionnaires. Studies that aimed to assess perceived oral health care needs should use standard and

    comprehensive questionnaires which included appropriate items on common types of oral health care

    services based on the characteristics of the target group. Accordance with perceived and normative need is

    matters that should be addressed in future research.

  • Dental care utilization in Tehran, Iran

    PRESENTER: Aida Kheiri

    AUTHORS: A. Kheiri2, 3

    , Z. Ghorbani1

    2. Shahid Beheshti University of Medical Scineces, Tehran, Iran

    Objectives: The aim of the study was to assess dental care utilization in adult citizens of Tehran.

    Methods: A cross-sectional telephone survey was performed on a stratified random sample of 1,100 adults

    aged 18–84 years living in Tehran. The interviews were carried out using a structured questionnaire covering

    dental care utilization in the past 12 months, dental insurance, received dental care in last dental visit,

    demographics, and socioeconomic status (SES). Data were analyzed using SPSS version 16.

    Results: Of the 1100 participants, 51% were men with the mean age of 39. A total of 53% of participants had

    visited a dentist in the past 12 months. The top 20% SES group had visited a dentist more frequently than

    people from the lowest 20% SES with an odds ratio (C1)=2.16(1.47,3.18). Sixty-four percent of participants

    went to private dental offices, 16% to their insurance clinics and 15% to public facilities. A total of 30% had

    complementary health. Only 10% visited a dentist for checkups and the majority of people visited a dentist

    because of dental problems. People from lower socioeconomic classes had used public dental facilities more

    frequently than those from higher socioeconomic classes (p

  • The effect of an informative leaflet on the knowledge regarding dental trauma among referral mothers to dental university

    PRESENTER: Fateme Sharifi

    AUTHORS: F. Molla Asadollah1, Z. Ghorbani2, M. Bargrizan1, F. sharifi3

    1. Shahid Beheshti University of Medical Scineces, Tehran, Iran

    Objectives: The aims of this study was to evaluate knowledge level among mothers admitted to the Shahid

    Beheshti's school of dentistry regarding dental trauma and to evaluate a simple leaflet as an measuring tool

    to enhance this knowledge.

    Methods: One hundred and fifty mothers of children receiving dental care at Shahid Beheshti Dental School,

    took part in this study. Before any intervention, questionnaires were distributed among all mothers(time 0).

    The level of knowledge of parents was measured in the three main categories: crown fracture, luxation and

    avulsion. After receiving the completed questionnaires, leaflets were distributed among case group(n=75)

    and immediately after reading the leaflet, the knowledge level of mothers in case group was examined with

    the same questionnaire(time 1). Finally, the Knowledge of mothers in both groups was evaluated three

    months later(time 2).

    Results: By scoring the questions, the level of knowledge was calculated. The mean of mothers' overall

    knowledge was 6.5(sd=1.9)at the time0. The mean of knowledge in the case group was 6.2 at the time 0 , 9.2

    at the time 1 and 8.5 at the time 2. The mean knowledge in control group was 6.8 at the time 0 and 7.6 at the

    time2. Increase in the knowledge score was seen in both groups, but the difference in knowledge score

    between two groups was significant. Improvements were seen in all the categories of knowledge as a result

    of reading the informative leaflet.

    Conclusions: Use of an informative leaflet enhanced the knowledge of mothers. Use of leaflets is an effective

    way to inform mothers about the management of traumatic dental injuries.

  • Session 2

    Calcium lactate pre-rinse effect on fluoride and calcium concentration in saliva and

    dental plaque after fluoride mouthwash

    PRESENTER: Navid Saadatfar

    AUTHORS: N. saadatfar1

    1. Shahid Beheshti University of Medical Scineces, Tehran, Iran

    Objectives: The amount of plaque calcium is depended on the use of calcium compounds.the aim of this

    study was to evaluate the calcium pre-rinse effect on salivary and dental plaque fluoride and calcium

    concenteration after the use of 0.2% sodium fluoride mouthwash.

    Methods: 30 subjects completed this double blind crossover trial.after prophylaxis and two weeks oral

    hygiene practice using non-fluoride and 15 subjects rinsed calcium lactate/sodium fluoride.one h and 12 h

    later,salivary and plaque samples were collected.after another prophylaxis and elapsing two weeks washout

    period with previous conditions,the participants rinsed the treatment not previously used.sampling was done

    at 1 and 12 hours.[f] and [ca] were analyzed using fluoride selective electrode and atomic absorption

    spectrometry.the data was analyzed using repeated measures ANOVA at the significant level of 5%.

    Results: There was significantly higher 1 h and 12 salivary [f] after calcium and fluoride rinses (p0.05).

    Conclusions: Salivary [f] increased by calcium and fluoride rinsing.however,our attempts to increase salivary

    [ca] and plaque [f] and [ca] had met with no success.

  • Oral Manifestations and Salivary Alterations in Patients with End-Stage Renal

    Disease (ESRD)

    PRESENTER:Mahnaz Torkaman

    AUTHORS: M. Torkaman1

    1.

    Dentistry, Iranian Ministry of Petroleum

    Objectives: To determine oral manifestations and salivary alterations in patients with ESRD.

    Methods: This case control study was performed on 20 ESRD patients undergoing hemodialysis and 20

    control subjects. Salivary concentrations of urea, calcium, and PH level measured for all subjects. Moreover,

    paleness of the skin and oral mucosal, symptoms of xerostomia, halitosis, uremic stomatitis, taste sensitivity,

    and radiographic changes were studied.

    Results: There was a significant difference (p < 0.05) in the average value of salivary urea concentration

    between two groups. Likewise, a meaningful statistical difference (p < 0.05) was noted while comparing the

    level of salivary PH between two groups. Statistically, no significant difference for calcium concentration

    between two groups was found. The majority of patients (95%) had signs of skin and mucosal paleness and

    80% complained of xerostomia while there was no sign of such symptoms in control group. Furthermore,

    there were meaningful differences in intensity of halitosis and uremic stomatitis between the two groups (p

  • Assessment of 5 and 10-years survival rate of oral cancer patients in Isfahan and

    determining the affecting factors.

    PRESENTER: Bahareh Tahani

    AUTHORS: B. Tahani1

    , S. razavi2

    , G. Yadegarfard3

    , M. Azari Rad4

    1.

    Department of Oral Public Health, School of Dentistry, Isfahan University of Medical Sciences

    Objectives: Oral cancer is considered as one of the few life-threatening oral diseases. The survival rate of this

    malignancy is affected by different patient and tumor related factors. The aim of this study is to evaluate the

    5 and 10 year survival of patients with oral cancer registered in dental school of Isfahan university and seyed

    al shohada hospital.

    Methods: Patients (240) who attended these two centers during the period 2004-2009 were included.

    Demographic data of patients and data about tumor characteristics including site, histologic type, staging and

    treatment type were obtained. Survival curves were generated using Kaplan-Maier curves. Univariate and

    multivariate analyses of the relations between survival and the mentioned factors were made using the log-

    rank test and Cox’s regression analysis. The statistical significance of the coefficients in the statistical analyses

    was tested at the 0.05 (α=0.05) level.

    Results: The overall survival rate was 57.6% and 24.7% for 5 and 10 years survival, respectively. Sex and

    staging of tumor were not in correlation to the survival. Age under 60 (OR= 0.089, P-value= 0.017),

    involvement of sites rather than tongue (OR=0.24, P-value=0.03) and combined treatment versus surgery

    (OR=0.073, P-value=0.004) were significantly in correlation to lower death rate.

    Conclusions: Among the probable factors, both demographic (age) and tumor related factors and treatments

    were effective in survival of patients. Therefore, survival of patients is a complicated factor and needs to be

    considered by both the patients and the care providers for early detection and diagnosis.

  • The Effect of Saliva's PH on the Fasting Students

    PRESENTER: Lina Zarifpour

    AUTHORS: L. Zarifpour1

    , A. Torabi1

    Objectives: This research is proposed to discover the line of PH level in the mouth of fasting students.

    Methods: The researchers used the experimental method which this involves manipulating conditions and

    studying effects to determine the PH level change which is based on the outcome of the study.

    Results: Based on the research conducted, the following findings have been noted: 1. 90% of the results were

    with in normal range of salivary PH level (6.4 - 7) Which indicates the accuracy of the hypothesis. Less than

    10% of the results were not with in normal PH level range There was an increase by 0.1 of the PH level every

    4hours and total of 0.2 form the first interval to the end . 2. General change of PH level in intervals was

    tendency to increase 0.2 in ph level with in normal range of 6,4 – 7 . PH level of the 83.33% of practitioners

    showed slight increase in level toward alkalinity during the experiment which is considered to be healthy and

    good and 15% showed decrease in the level of PH and 1.66% showed no change in the evel of the ph. The

    diversed results were in close approximity with normal range and were not very distinct to be worried about.

    Conclusions: Based on the above findings, following have been concluded: 1. The incidence of threatening

    issue concerning oral environment upon fasting for 12 hours is very low (less than

    10%). 2. Acceptable oral hygiene can be maintained through fasting easily. 3. Fasting can maintain alkaline

    environment which is reducing the incidence of dental caries (more thn 90%).

  • Trends of oral cavity, laryngeal and oropharyngeal hard and soft tissue cysts, tumors

    and cancers incidence in Iranian population (1991-2015)

    PRESENTER: Fatemeh Hosseini

    AUTHORS: F. Mashhadiabbas1, 2

    , F. Hosseini1

    , H. Ramezani1

    1. Shahid Beheshti University of Medical Scineces, Tehran, Iran

    Objectives: Head and neck lesions are one of the recurrent lesions in the body including odontogentic cysts

    and tumors, hard and soft tissue tumors, salivary gland and epithelial malignancies. The prevalence of these

    lesions has differently reported in the racial groups and populations. The present study assessed the

    incidence of the lesions of the head and neck in patients referred to Shahid Beheshti Dental School during

    1991-2015 for twenty four years.

    Methods: We obtained all diagnosed cases of head and neck cancer on the pathology Department of Shahid

    Beheshti University Dental School during 1991-2015 estimat