Homayoun H. Zadeh, DDS, PhD

CURRICULUM VITAE

2019

Personal information

Work Address Brighton Periodontal & Implant Dental Group6325 Topanga Canyon Blvd Suite 433Woodland Hills, CA 91367

VISTA Institute for Therapeutic Innovations6325 Topanga Canyon Blvd Suite 305Woodland Hills, CA 91367

Work Telephone No. Voice: (818) 703-7733

Fax: (818) 703-8106

E-mail homazadeh@gmail.com

Citizenship U.S.A.

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UNIVERSITY EDUCATION

1987- 1992 University of Connecticut Health Center, School Medicine, Dept. of Pathology: Graduate Training in Immunology (Ph.D.)

1987- 1992 University of Connecticut Health Center, School of Dental Medicine, Dept. of Periodontology: Certificate of Clinical Training in Periodontology

1983 - 1987 University of Southern California, School of Dentistry (D.D.S.)

1980 - 1983 University of California, Los Angeles: Biology (B.S.)

1978 - 1980 College of Notre Dame, Belmont, CA: Biology

ACADEMIC APPOINTMENTS

2012-2019 Director, Post-doctoral Periodontology Program: University of Southern California, Herman Ostrow School of DentistryDivision of Periodontology

2003-2006 Chair, Periodontology Section: University of Southern California, Herman Ostrow School of Dentistry

Division of Primary Oral Health Care

2003-2019 Associate Professor: University of Southern California, Herman Ostrow School of DentistryDivision of Periodontology

2004-2019 Director: USC Annual Periodontal & Implant Symposium

2001-2003 Assistant Professor: University of Southern California, School of Dentistry Division of Diagnostic Sciences

1994-2001 Assistant Professor: University of Southern California, School of Dentistry Department of Periodontology

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1993-1994 Clinical Assistant Professor: University of Southern California, School of Dentistry Department of Periodontology

1992-1993 Clinical fellow: University of Connecticut Health Center, School of Dental Medicine, Department of Periodontology

1988-1992 Clinical Preceptor, University of Connecticut Health Center, School of Dental Medicine, Department of Periodontology

RESEARCH EXPERIENCE

2007-2019 Clinical trial of implant outcomes: multi-center trial in collaboration with the University of Gothenburg, Sweden; Apeldoorn, The Netherlands; Balwyn, Australia and King’s College, London, UK; entitled: “An open, prospective, randomized, multicenter study comparing Osseospeed™ implant 6 mm with Osseospeed™ implant 11 mm in the posterior maxilla and mandible. A 5-year follow-up study”

2004-2019 Tissue engineering application of stem cells and growth factors

1993-2019 Mechanisms of immunoregulation in response to oral bacteria

1997–2003 Utilizing psychoneuroimmunology in understanding

the host response to periodontal bacteria

1989 -1992 Graduate Thesis Research: supervised by Dr. Irving Goldschneider, Professor, Department of Pathology, University of Connecticut, School of Medicine. Thesis title: Recent thymic emigrants in normal and cyclosporine-treated rats

1988-1989 Laboratory Rotation supervised by Dr. Donald Kreutzer, University of Connecticut, School of Medicine, Department of Pathology: The effects of fibronectin synthetic peptides on human neutrophil locomotion.

1984-1987 Directed Research supervised by Dr. Steven Schonfeld, University of Southern California, School of Dentistry, Department of Periodontics: The role of L-form bacteria in periodontal disease.

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EDITORIAL EXPERIENCE

ad hoc reviewer, International Journal of Maxillofacial Implants

ad hoc reviewer, Clinical Implant Dentistry and Related Research

ad hoc reviewer, Clinical Oral Implant Research

ad hoc reviewer, Bone

ad hoc reviewer, Materials Science & Engineering C

ad hoc reviewer, Journal of Tissue Engineering

ad hoc reviewer, Journal of Periodontology

ad hoc reviewer, Journal of Clinical Periodontology

ad hoc reviewer, Clinical Oral Implant Research

ad hoc reviewer, Clinical Implant Dentistry & Related Research

ad hoc reviewer, Infection and Immunity

ad hoc reviewer, Archives of Oral Biology

ad hoc reviewer, Journal of Dental Research

ad hoc reviewer, Journal of Periodontal Research

ad hoc reviewer, Oral Microbiology and Immunology

GRANT SCIENTIFIC REVIEW EXPERIENCE

2004-2010 Chartered member of the Oral, Craniofacial and Dental Sciences Study Section, National Institutes of Health, Center for Scientific Review (CSR)

2010-present ad hoc reviewer, Oral, Craniofacial and Dental Sciences Study Section, National Institutes of Health, Center for Scientific Review (CSR)

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2006 Acting Chair, Oral, Craniofacial and Dental Sciences Study Section, National Institutes of Health, Center for Scientific Review (CSR)

2002-present Infection & Immunity PanelThe Wellcome Trust

HONORS, AWARDS & FELLOWSHIPS

1987-1992 Recipient of National Research Service Award (NRSA) postdoctoral training grant fellowship

1987 Periodontology Award, University of Southern California, School of Dentistry

1996 Zumberg Fellowship Award, University of Southern California

1998 Travel grant to attend NIH-spnosored “Interdisciplinary workshop on Psychoneuroimmunology”: University of Misouri-Kansas City, MO

2001 Teaching Excellence Award: presented by the Associated Student Body

2003 Clark L. Hull Award for Scientific Excellence in Writing on Experimental Hypnosis from the American Society of Clinical Hypnosis

2006 Faculty Contribution Award, University of Southern California

RESEARCH GRANTS

2014-2015 Antibody mediated osseous regenerationRole: Principal investigatorAgency:Osteology Foundation

2013-2014 Antibody mediated osseous regenerationRole: Principal investigatorAgency:Academy of Osseointegration Foundation

2012-2017 Novel clone-specific virulence determinants of Actinobacillus actinomycetemcomitansRole: Co-Principal investigatorAgency: National Institute of Dental and Craniofacial Research

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Type: R01 (R01-DE012212, Years -11-16) competitive renewal

2008-2013 Role: Principal investigatorSponsor: Astratech AB “An open, prospective, randomized, multicenter study comparing Osseospeed™ implant 6 mm with Osseospeed™ implant 11 mm in the posterior maxilla and mandible. A 5-year follow-up study”

2003-2009 Subversion of T Cell Response to Actinobacillus actinomycetemcomitansRole: Principal investigatorAgency: National Institute of Dental and Craniofacial Research Type: R01 (R01-DE010861, Years 6-10) competitive renewalGoals: The major objective of this project is to test the hypothesis that Actinobacillus actinomycetemcomitans evades the host immune response, thereby contributing to the pathology of oral infections.Total costs: $1,422,312.

1996-2002 Superantigens in Periodontal DiseasesRole: Principal investigatorAgency: National Institute of Dental and Craniofacial Research Type: R29 (R29-DE10861, Years 1-5)Goals: The major objective of this project is to test the hypothesis that periodontal pathogenic bacteria produce superantigens that may compromise the antigen-specific response Total costs: $572, 250

2000-2002Stress Management and T Cell Responses in PeriodontitisRole: Co-investigator Principal Investigator: Gary WoodAgency: National Institute of Dental and Craniofacial ResearchType: R03 (DE13271, Years 1-2)Total costs: $81, 458 Goals: The focus of this study is to test the hypothesis that a non-pharmacological stress management intervention can induce alterations in the psychologic, neuroendocrine and T cell cytokines in periodontal disease.

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1999-2000 Principal investigator: “The effects of periodontal infections on the systemic immune response”: Jewish Community Endowment Research AwardTotal costs: $25, 000/year

1999-2000 Principal investigator: “Apoptosis of T lymphocytes by Actinobacillus actinomycetemcomitans” Research Small Initiative Grant USCTotal costs: $5, 000

1995-1996 Principal investigator: “ Superantigenic properties of Periodontitis-associated bacteria”: Zumberg Award, University of Southern CaliforniaTotal costs: $25, 000

LEADERSHIP ROLES

2018 Board member: Western Society of Periodontology

2017 President: Western Society of Periodontology

2016 President-Elect: Western Society of Periodontology

2015 Treasurer: Western Society of Periodontology

2002-2003 President: Iranian-American Dental Association

PROFESSIONAL ORGANIZATIONS

American Academy of Periodontology

American Academy of Esthetic Dentistry

Academy of Osseointegration

Western Society of Periodontology

California Society of Periodontists

American Academy of Implant Dentistry

American Dental Association

California Dental Association

Santa Barbara/Ventura County Dental Society

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BOARD CERTIFICATION AND LICENSURE

California Dental License (# 035503)National Dental BoardDiplomate, American Board of Periodontology

RESEARCH CERTIFICATION

Human Subjects CertificationAnimal Research Certification

CLINICAL EXPERIENCE

1993- Present Private practice limited to periodontology and implant dentistry

PUBLICATIONS IN REFEREED JOURNALS

Accepted and in press

Gil A, Bakhshalian N, Min S, Zadeh HH. Three-Dimensional Volumetric Analysis of Multiple Gingival Recession Defects Treated by Vestibular Incision Subperiosteal Tunnel Access (VISTA). Int J Periodontics Restorative Dent. 2019 (in press)

Hameed S, Alwazan E, Bakhshalian N, Wallace S, Zadeh HH. Maxillary sinus floor and alveolar crest alterations following extraction of maxillary molars: A retrospective CBCT analysis. Int J Periodontics Restorative Dent. 2019 (in press)

Kim JS, Ahn JP, Kim YH, Seo KW, Zadeh H, Kim SH. Atomic layout of anorthodontic titanium mini-implant in human tissue: Insights into the possiblemechanisms during osseointegration. Angle Orthod. 2019 Mar;89(2):292-298. doi:10.2319/051418-354.1. Epub 2018 Nov 28. PubMed PMID: 30484324.

Published

1: Khojasteh A, Hosseinpour S, Rezai Rad M, Alikhasi M, Zadeh HH. Buccal fatpad-derived stem cells with anorganic bovine bone mineral scaffold foraugmentation of atrophic posterior mandible: An exploratory prospective clinical study. Clin Implant Dent Relat Res. 2019 Mar 1. doi: 10.1111/cid.12729. [Epubahead of print] PubMed PMID: 30821120.

2: Wu IH, Bakhshalian N, Galaustian R, Naini RB, Min S, Freire M, Zadeh HH.Retrospective Analysis of the Outcome of Ridge Preservation with Anorganic BovineBone Mineral: Marginal Bone Level at Implants Placed Following Healing of Grafted

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Extraction Sockets. Int J Periodontics Restorative Dent. 2019Jan/Feb;39(1):131-140. doi: 10.11607/prd.3308. PubMed PMID: 30543734.

3: Kim JS, Ahn JP, Kim YH, Seo KW, Zadeh H, Kim SH. Atomic layout of anorthodontic titanium mini-implant in human tissue: Insights into the possiblemechanisms during osseointegration. Angle Orthod. 2019 Mar;89(2):292-298. doi:10.2319/051418-354.1. Epub 2018 Nov 28. PubMed PMID: 30484324.

4: Gil A, Bakhshalian N, Min S, Zadeh HH. Treatment of multiple recession defectswith vestibular incision subperiosteal tunnel access (VISTA): A retrospectivepilot study utilizing digital analysis. J Esthet Restor Dent. 2018 Nov;30(6):572-579. doi: 10.1111/jerd.12434. Epub 2018 Oct 27. PubMed PMID:30367715.

5: Zadeh HH, Guljé F, Palmer PJ, Abrahamsson I, Chen S, Mahallati R, Stanford CM.Marginal bone level and survival of short and standard-length implants after 3years: An Open Multi-Center Randomized Controlled Clinical Trial. Clin OralImplants Res. 2018 Aug;29(8):894-906. doi: 10.1111/clr.13341. Epub 2018 Jul 12.PubMed PMID: 30003598.

6: Min S, Freire M, Bakshallian N, Wu I, Zadeh HH. A Histologic andHistomorphometric Retrospective Analysis of the Outcomes of Ridge PreservationUsing Anorganic Bovine Bone Minerals and a Nonresorbable Membrane. Int JPeriodontics Restorative Dent. 2018 September/October;38(5):637–644. doi:10.11607/prd.3313. Epub 2018 Jun 12. PubMed PMID: 29897354.

7: Bakhshalian N, Abdelhamid A, Park YJ, Zadeh HH. Histological andHistomorphometric Response to SocketKAP™ and SocketKAGE™ Used for RidgePreservation and Repair: Results From a Randomized Controlled Clinical Trial. JOral Maxillofac Surg. 2018 Sep;76(9):1884-1892. doi: 10.1016/j.joms.2018.04.007. Epub 2018 Apr 12. PubMed PMID: 29738746.

8: Khojasteh A, Hosseinpour S, Dehghan MM, Mashhadiabbas F, Rezai Rad M, AnsariS, Farzad Mohajeri S, Zadeh HH. Antibody-Mediated Osseous Regeneration for BoneTissue Engineering in Canine Segmental Defects. Biomed Res Int. 2018 Feb28;2018:9508721. doi: 10.1155/2018/9508721. eCollection 2018. PubMed PMID:29682573; PubMed Central PMCID: PMC5851338.

9: Hosseinpour S, Rad MR, Khojasteh A, Zadeh HH. Antibody Administration for BoneTissue Engineering: A Systematic Review. Curr Stem Cell Res Ther. 2018;13(4):292-315. doi: 10.2174/1574888X13666180207095314. Review. PubMed PMID: 29412118.

10: Xie Y, Su Y, Min S, Tang J, Goh BT, Saigo L, Ansari S, Moshaverinia A, Zhang

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C, Wang J, Liu Y, Khojasteh A, Zadeh HH, Wang S. Erratum to "Collagen SpongeFunctionalized with Chimeric Anti-BMP-2 Monoclonal Antibody Mediates Repair ofCritical-Size Mandibular Continuity Defects in a Nonhuman Primate Model". Biomed Res Int. 2017;2017:3689716. doi: 10.1155/2017/3689716. Epub 2017 Dec 3. PubMedPMID: 29333440; PubMed Central PMCID: PMC5733217.

11: Bakhshalian N, Freire M, Min S, Wu I, Zadeh HH. Retrospective Analysis of theOutcome of Ridge Preservation with Anorganic Bovine Bone Minerals: Microcomputed Tomographic Assessment of Wound Healing in Grafted Extraction Sockets. Int JPeriodontics Restorative Dent. 2018 Jan/Feb;38(1):103-111. doi:10.11607/prd.3309. PubMed PMID: 29240211.

12: Zhang W, Zhou L, Dang J, Zhang X, Wang J, Chen Y, Liang J, Li D, Ma J, YuanJ, Chen W, Zadeh HH, Olsen N, Zheng SG. Human Gingiva-Derived Mesenchymal Stem Cells Ameliorate Streptozoticin-induced T1DM in mice via Suppression of Teffector cells and Up-regulating Treg Subsets. Sci Rep. 2017 Nov 10;7(1):15249.doi: 10.1038/s41598-017-14979-5. PubMed PMID: 29127315; PubMed Central PMCID:PMC5681565.

13: Guo L, Min S, Su Y, Tang J, Du J, Goh BT, Saigo L, Wang S, Ansari S,Moshaverinia A, Zadeh HH, Liu Y. Collagen sponge functionalized with chimericanti-BMP-2 monoclonal antibody mediates repair of nonunion tibia defects in anonhuman primate model: An exploratory study. J Biomater Appl. 2017Oct;32(4):425-432. doi: 10.1177/0885328217733262. PubMed PMID: 28992803.

14: Rojas-Vizcaya F, Zadeh HH. Minimizing the discrepancy between implantplatform and alveolar bone for tilted implants with a sloped implant platform: A clinical report. J Prosthet Dent. 2018 Mar;119(3):319-324. doi:10.1016/j.prosdent.2017.04.004. Epub 2017 Jun 23. PubMed PMID: 28652075.

15: Ansari S, Chen C, Hasani-Sadrabadi MM, Yu B, Zadeh HH, Wu BM, Moshaverinia A. Hydrogel elasticity and microarchitecture regulate dental-derived mesenchymalstem cell-host immune system cross-talk. Acta Biomater. 2017 Sep 15;60:181-189.doi: 10.1016/j.actbio.2017.07.017. Epub 2017 Jul 12. PubMed PMID: 28711686;PubMed Central PMCID: PMC5581234.

16: Mahabady S, Tjokro N, Aharonian S, Zadeh HH, Chen C, Allayee H, SedghizadehPP. The in vivo T helper type 17 and regulatory T cell immune responses toAggregatibacter actinomycetemcomitans. Mol Oral Microbiol. 2017 Dec;32(6):490-499. doi: 10.1111/omi.12187. Epub 2017 Jun 27. PubMed PMID: 28544588; PubMed Central PMCID: PMC5842142.

17: Su Y, Tang J, Min S, Guo L, Liu Y, Xie Y, Xiong J, Wang S, Araújo MG, ZadehHH, Liu Y. Alveolar ridge dimensional changes following ridge preservation

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procedure with novel devices: part 3 - histological analysis in non-human primatemodel. Clin Oral Implants Res. 2017 Nov;28(11):e252-e261. doi: 10.1111/clr.13010.Epub 2017 Apr 19. PubMed PMID: 28422326.

18: Xie Y, Su Y, Min S, Tang J, Goh BT, Saigo L, Ansari S, Moshaverinia A, Zhang C, Wang J, Liu Y, Khojasteh A, Zadeh HH, Wang S. Collagen Sponge Functionalizedwith Chimeric Anti-BMP-2 Monoclonal Antibody Mediates Repair of Critical-SizeMandibular Continuity Defects in a Nonhuman Primate Model. Biomed Res Int.2017;2017:8094152. doi: 10.1155/2017/8094152. Epub 2017 Mar 16. Erratum in:Biomed Res Int. 2017;2017:3689716. PubMed PMID: 28401163; PubMed Central PMCID: PMC5376406.

19: Hadavi M, Hasannia S, Faghihi S, Mashayekhi F, Zadeh HH, Mostofi SB. Novelcalcified gum Arabic porous nano-composite scaffold for bone tissue regeneration.Biochem Biophys Res Commun. 2017 Jul 8;488(4):671-678. doi:10.1016/j.bbrc.2017.03.046. Epub 2017 Mar 14. PubMed PMID: 28302485.

20: Huang F, Chen M, Chen W, Gu J, Yuan J, Xue Y, Dang J, Su W, Wang J, Zadeh HH,He X, Rong L, Olsen N, Zheng SG. Human Gingiva-Derived Mesenchymal Stem Cells Inhibit Xeno-Graft-versus-Host Disease via CD39-CD73-Adenosine and IDO Signals. Front Immunol. 2017 Feb 2;8:68. doi: 10.3389/fimmu.2017.00068. eCollection 2017. PubMed PMID: 28210258; PubMed Central PMCID: PMC5288353.

21: Khojasteh A, Motamedian SR, Sharifzadeh N, Zadeh HH. The influence of initialalveolar ridge defect morphology on the outcome of implants in augmented atrophicposterior mandible: an exploratory retrospective study. Clin Oral Implants Res.2017 Oct;28(10):e208-e217. doi: 10.1111/clr.12991. Epub 2016 Nov 2. PubMed PMID: 27804178.

22: Ansari S, Chen C, Xu X, Annabi N, Zadeh HH, Wu BM, Khademhosseini A, Shi S,Moshaverinia A. Muscle Tissue Engineering Using Gingival Mesenchymal Stem CellsEncapsulated in Alginate Hydrogels Containing Multiple Growth Factors. Ann BiomedEng. 2016 Jun;44(6):1908-20. doi: 10.1007/s10439-016-1594-6. Epub 2016 Mar 23.PubMed PMID: 27009085; PubMed Central PMCID: PMC4880526.

23: Freire MO, Devaraj A, Young A, Navarro JB, Downey JS, Chen C, Bakaletz LO,Zadeh HH, Goodman SD. A bacterial-biofilm-induced oral osteolytic infection canbe successfully treated by immuno-targeting an extracellular nucleoid-associated protein. Mol Oral Microbiol. 2017 Feb;32(1):74-88. doi: 10.1111/omi.12155. Epub2016 Apr 5. PubMed PMID: 26931773; PubMed Central PMCID: PMC5010536.

24: Ryu KH, Min S, You HK, Sin YW, Lee W, Lee J, Kiss A, Almohaimeed M, Zadeh HH.Alveolar ridge dimensional changes following ridge preservation procedure using

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SocketKAP(™) : exploratory study of serial cone-beam computed tomography andhistologic analysis in canine model. Clin Oral Implants Res. 2016Sep;27(9):1144-51. doi: 10.1111/clr.12711. Epub 2015 Dec 13. PubMed PMID:26660705.

25: Zadeh HH, Abdelhamid A, Omran M, Bakhshalian N, Tarnow D. An open randomized controlled clinical trial to evaluate ridge preservation and repair usingSocketKAP(™) and SocketKAGE(™) : part 1-three-dimensional volumetric soft tissue analysis of study casts. Clin Oral Implants Res. 2016 Jun;27(6):640-9. doi:10.1111/clr.12714. Epub 2015 Nov 2. PubMed PMID: 26521754.

26: Abdelhamid A, Omran M, Bakhshalian N, Tarnow D, Zadeh HH. An open randomized controlled clinical trial to evaluate ridge preservation and repair usingSocketKAP(™) and SocketKAGE(™) : part 2 - three-dimensional alveolar bonevolumetric analysis of CBCT imaging. Clin Oral Implants Res. 2016 Jun;27(6):631-9. doi: 10.1111/clr.12687. Epub 2015 Oct 31. PubMed PMID: 26518980.

27: Omran M, Min S, Abdelhamid A, Liu Y, Zadeh HH. Alveolar ridge dimensionalchanges following ridge preservation procedure: part-2 - CBCT 3D analysis innon-human primate model. Clin Oral Implants Res. 2016 Jul;27(7):859-66. doi:10.1111/clr.12701. Epub 2015 Oct 25. PubMed PMID: 26498407.

28: Ansari S, Phark JH, Duarte S Jr, Paulino da Silva M, Sharifzadeh N,Moshaverinia A, Zadeh HH. Biomechanical analysis of engineered bone withanti-BMP2 antibody immobilized on different scaffolds. J Biomed Mater Res B Appl Biomater. 2016 Oct;104(7):1465-73. doi: 10.1002/jbm.b.33492. Epub 2015 Aug 7.PubMed PMID: 26252572; PubMed Central PMCID: PMC4744810.

29: Diniz IM, Chen C, Ansari S, Zadeh HH, Moshaverinia M, Chee D, Marques MM, ShiS, Moshaverinia A. Gingival Mesenchymal Stem Cell (GMSC) Delivery System Based on RGD-Coupled Alginate Hydrogel with Antimicrobial Properties: A Novel TreatmentModality for Peri-Implantitis. J Prosthodont. 2016 Feb;25(2):105-15. doi:10.1111/jopr.12316. Epub 2015 Jul 27. PubMed PMID: 26216081; PubMed CentralPMCID: PMC4729657.

30: Ansari S, Freire M, Choi MG, Tavari A, Almohaimeed M, Moshaverinia A, ZadehHH. Effects of the orientation of anti-BMP2 monoclonal antibody immobilized onscaffold in antibody-mediated osseous regeneration. J Biomater Appl. 2015Nov;30(5):558-67. doi: 10.1177/0885328215594704. Epub 2015 Jul 15. PubMed PMID: 26184354; PubMed Central PMCID: PMC4670793.

31: Moshaverinia A, Chen C, Xu X, Ansari S, Zadeh HH, Schricker SR, Paine ML,Moradian-Oldak J, Khademhosseini A, Snead ML, Shi S. Regulation of the StemCell-Host Immune System Interplay Using Hydrogel Coencapsulation System with an

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Anti-Inflammatory Drug. Adv Funct Mater. 2015 Apr 15;25(15):2296-2307. PubMedPMID: 26120294; PubMed Central PMCID: PMC4478611.

32: Kim SH, Ahn JP, Zadeh HH, Liou EJ. Osteogenic biomaterials in contemporarydentistry. Biomed Res Int. 2015;2015:945320. doi: 10.1155/2015/945320. Epub 2015 Apr 8. PubMed PMID: 25950004; PubMed Central PMCID: PMC4407404.

33: Diniz IM, Chen C, Xu X, Ansari S, Zadeh HH, Marques MM, Shi S, MoshaveriniaA. Pluronic F-127 hydrogel as a promising scaffold for encapsulation of dental-derived mesenchymal stem cells. J Mater Sci Mater Med. 2015 Mar;26(3):153. doi: 10.1007/s10856-015-5493-4. Epub 2015 Mar 15. PubMed PMID: 25773231; PubMedCentral PMCID: PMC4477746.

34: Freire M, Choi JH, Nguyen A, Chee YD, Kook JK, You HK, Zadeh HH. Application of AMOR in craniofacial rabbit bone bioengineering. Biomed Res Int. 2015;2015:628769. doi: 10.1155/2015/628769. Epub 2015 Jan 29. PubMed PMID:25705677; PubMed Central PMCID: PMC4325208.

35: Min S, Liu Y, Tang J, Xie Y, Xiong J, You HK, Zadeh HH. Alveolar ridgedimensional changes following ridge preservation procedure with novel devices:Part 1--CBCT linear analysis in non-human primate model. Clin Oral Implants Res. 2016 Jan;27(1):97-105. doi: 10.1111/clr.12521. Epub 2015 Feb 6. PubMed PMID:25655480; PubMed Central PMCID: PMC5024076.

36: Tatakis DN, Chambrone L, Allen EP, Langer B, McGuire MK, Richardson CR,Zabalegui I, Zadeh HH. Periodontal soft tissue root coverage procedures: aconsensus report from the AAP Regeneration Workshop. J Periodontol. 2015 Feb;86(2Suppl):S52-5. doi: 10.1902/jop.2015.140376. Epub 2014 Oct 15. PubMed PMID:25315018.

37: Block MS, Clem D, Jensen OT, Le B, Lozada J, Moy PK, Norton MR, Testori T,Valentini P, Wallace SS, Zadeh HH. Letter to the Editor Re: Kim, Nowzari, andRich (2013). Clin Implant Dent Relat Res. 2016 Feb;18(1):5-7. doi:10.1111/cid.12241. Epub 2014 Sep 2. PubMed PMID: 25181486.

38: Ansari S, Freire MO, Pang EK, Abdelhamid AI, Almohaimeed M, Zadeh HH.Immobilization of murine anti-BMP-2 monoclonal antibody on various biomaterialsfor bone tissue engineering. Biomed Res Int. 2014;2014:940860. doi:10.1155/2014/940860. Epub 2014 Jul 23. PubMed PMID: 25147826; PubMed CentralPMCID: PMC4132312.

39: Moshaverinia A, Xu X, Chen C, Ansari S, Zadeh HH, Snead ML, Shi S.Application of stem cells derived from the periodontal ligament or gingival

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tissue sources for tendon tissue regeneration. Biomaterials. 2014Mar;35(9):2642-50. doi: 10.1016/j.biomaterials.2013.12.053. Epub 2014 Jan 4.PubMed PMID: 24397989; PubMed Central PMCID: PMC3929697.

40: Borzabadi-Farahani A, Zadeh HH. Adjunctive Orthodontic Applications in DentalImplantology. J Oral Implantol. 2015 Aug;41(4):501-8. doi:10.1563/AAID-JOI-D-13-00235. Epub 2013 Oct 31. PubMed PMID: 24175964.

41: Moshaverinia A, Chen C, Xu X, Akiyama K, Ansari S, Zadeh HH, Shi S. Boneregeneration potential of stem cells derived from periodontal ligament orgingival tissue sources encapsulated in RGD-modified alginate scaffold. TissueEng Part A. 2014 Feb;20(3-4):611-21. doi: 10.1089/ten.TEA.2013.0229. Epub 2013Nov 6. PubMed PMID: 24070211; PubMed Central PMCID: PMC3926152.

42: Ansari S, Moshaverinia A, Pi SH, Han A, Abdelhamid AI, Zadeh HH.Functionalization of scaffolds with chimeric anti-BMP-2 monoclonal antibodies forosseous regeneration. Biomaterials. 2013 Dec;34(38):10191-8. doi:10.1016/j.biomaterials.2013.08.069. Epub 2013 Sep 19. PubMed PMID: 24055525;PubMed Central PMCID: PMC3838877.

43: Manrique P, Freire MO, Chen C, Zadeh HH, Young M, Suci P. Perturbation of theindigenous rat oral microbiome by ciprofloxacin dosing. Mol Oral Microbiol. 2013 Oct;28(5):404-14. doi: 10.1111/omi.12033. Epub 2013 Jul 12. PubMed PMID:23844936; PubMed Central PMCID: PMC3767763.

44: Moshaverinia A, Ansari S, Chen C, Xu X, Akiyama K, Snead ML, Zadeh HH, Shi S.Co-encapsulation of anti-BMP2 monoclonal antibody and mesenchymal stem cells inalginate microspheres for bone tissue engineering. Biomaterials. 2013Sep;34(28):6572-9. doi: 10.1016/j.biomaterials.2013.05.048. Epub 2013 Jun 14.PubMed PMID: 23773817; PubMed Central PMCID: PMC3715959.

45: Freire MO, Kim HK, Kook JK, Nguyen A, Zadeh HH. Antibody-mediated osseousregeneration: the early events in the healing response. Tissue Eng Part A. 2013May;19(9-10):1165-74. doi: 10.1089/ten.TEA.2012.0282. Epub 2013 Jan 8. PubMedPMID: 23190409.

46: Atieh MA, Zadeh H, Stanford CM, Cooper LF. Survival of short dental implants for treatment of posterior partial edentulism: a systematic review. Int J OralMaxillofac Implants. 2012 Nov-Dec;27(6):1323-31. Review. PubMed PMID: 23189281.

47: Wallace SS, Tarnow DP, Froum SJ, Cho SC, Zadeh HH, Stoupel J, Del Fabbro M,Testori T. Maxillary sinus elevation by lateral window approach: evolution oftechnology and technique. J Evid Based Dent Pract. 2012 Sep;12(3 Suppl):161-71.

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doi: 10.1016/S1532-3382(12)70030-1. Review. PubMed PMID: 23040346.

48: Guljé F, Abrahamsson I, Chen S, Stanford C, Zadeh H, Palmer R. Implants of 6 mm vs. 11 mm lengths in the posterior maxilla and mandible: a 1-year multicenter randomized controlled trial. Clin Oral Implants Res. 2013 Dec;24(12):1325-31.doi: 10.1111/clr.12001. Epub 2012 Sep 3. PubMed PMID: 22938573.

49: Kim BS, Kim HJ, Kim JS, You YO, Zadeh H, Shin HI, Lee SJ, Park YJ, Takata T, Pi SH, Lee J, You HK. IFITM1 increases osteogenesis through Runx2 in humanalveolar-derived bone marrow stromal cells. Bone. 2012 Sep;51(3):506-14. doi:10.1016/j.bone.2012.05.012. Epub 2012 May 23. PubMed PMID: 22634173.

50: Zadeh HH. Minimally invasive treatment of maxillary anterior gingivalrecession defects by vestibular incision subperiosteal tunnel access andplatelet-derived growth factor BB. Int J Periodontics Restorative Dent. 2011Nov-Dec;31(6):653-60. PubMed PMID: 22140667.

51: Kim SH, Kim I, Jeong DM, Chung KR, Zadeh H. Corticotomy-assisteddecompensation for augmentation of the mandibular anterior ridge. Am J OrthodDentofacial Orthop. 2011 Nov;140(5):720-31. doi: 10.1016/j.ajodo.2009.12.040.PubMed PMID: 22051493.

52: Freire MO, You HK, Kook JK, Choi JH, Zadeh HH. Antibody-mediated osseousregeneration: a novel strategy for bioengineering bone by immobilized anti-bonemorphogenetic protein-2 antibodies. Tissue Eng Part A. 2011 Dec;17(23-24):2911-8.doi: 10.1089/ten.tea.2010.0584. Epub 2011 Aug 26. PubMed PMID: 21870943.

53: Kim BS, Kim YC, Zadeh H, Park YJ, Pi SH, Shin HS, You HK. Effects of thedichloromethane fraction of Dipsaci Radix on the osteoblastic differentiation of human alveolar bone marrow-derived mesenchymal stem cells. Biosci BiotechnolBiochem. 2011;75(1):13-9. Epub 2011 Jan 7. PubMed PMID: 21228489.

54: Freire MO, Sedghizadeh PP, Schaudinn C, Gorur A, Downey JS, Choi JH, Chen W, Kook JK, Chen C, Goodman SD, Zadeh HH. Development of an animal model forAggregatibacter actinomycetemcomitans biofilm-mediated oral osteolytic infection:a preliminary study. J Periodontol. 2011 May;82(5):778-89. doi:10.1902/jop.2010.100263. Epub 2011 Jan 11. PubMed PMID: 21222546; PubMed Central PMCID: PMC3496747.

55: Zadeh HH, Daftary F. Minimally invasive surgery: an alternative approach for periodontal and implant reconstruction. J Calif Dent Assoc. 2004Dec;32(12):1022-30. Review. PubMed PMID: 15715379.

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56: Zadeh HH. Implant site development: clinical realities of today and theprospects of tissue engineering. J Calif Dent Assoc. 2004 Dec;32(12):1011-20.Review. PubMed PMID: 15715378.

57: Zadeh HH, Daftary F. Implant designs for the spectrum of esthetic andfunctional requirements. J Calif Dent Assoc. 2004 Dec;32(12):1003-10. PubMedPMID: 15715377.

58: Nalbant A, Chen C, Wang Y, Zadeh HH. Induction of T-cell apoptosis byActinobacillus actinomycetemcomitans mutants with deletion of ltxA and cdtABCgenes: possible activity of GroEL-like molecule. Oral Microbiol Immunol. 2003Dec;18(6):339-49. PubMed PMID: 14622339.

59: Wood GJ, Bughi S, Morrison J, Tanavoli S, Tanavoli S, Zadeh HH. Hypnosis,differential expression of cytokines by T-cell subsets, and thehypothalamo-pituitary-adrenal axis. Am J Clin Hypn. 2003 Jan;45(3):179-96. PubMedPMID: 12570090.

60: Nalbant A, Zadeh HH. Actinobacillus actinomycetemcomitans induces apoptosisof T lymphocytes by the Fas and Fas ligand pathway. Oral Microbiol Immunol. 2002 Oct;17(5):277-84. PubMed PMID: 12354208.

61: Stewart JE, Wager KA, Friedlander AH, Zadeh HH. The effect of periodontaltreatment on glycemic control in patients with type 2 diabetes mellitus. J ClinPeriodontol. 2001 Apr;28(4):306-10. PubMed PMID: 11314885.

62: Zadeh HH, Nalbant A, Park K. Large-scale early in vitro response toactinobacillus actinomycetemcomitans suggests superantigenic activation ofT-cells. J Dent Res. 2001 Jan;80(1):356-62. PubMed PMID: 11269729.

63: Nalbant A, Zadeh HH. Evidence for apoptosis of the majority of T cellsactivated in vitro with Actinobacillus actinomycetemcomitans. Oral MicrobiolImmunol. 2000 Oct;15(5):290-8. PubMed PMID: 11154419.

64: Zadeh HH, Tanavoli S, Haines DD, Kreutzer DL. Despite large-scale T cellactivation, only a minor subset of T cells responding in vitro to Actinobacillus actinomycetemcomitans differentiate into effector T cells. J Periodontal Res.2000 Jun;35(3):127-36. PubMed PMID: 10929867.

65: Karimzadeh K, Morrison J, Zadeh HH. Comparison of gingival and peripheralblood T cells among patients with periodontitis suggests skewing of the gingival

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T cell antigen receptor V beta repertoire. J Periodontal Res. 1999Nov;34(8):445-56. PubMed PMID: 10697801.

66: Wood GJ, Zadeh HH. Potential adjunctive applications of hypnosis in themanagement of periodontal diseases. Am J Clin Hypn. 1999 Jan;41(3):212-25.Review. PubMed PMID: 10554383.

67: Contreras A, Zadeh HH, Nowzari H, Slots J. Herpesvirus infection ofinflammatory cells in human periodontitis. Oral Microbiol Immunol. 1999Aug;14(4):206-12. PubMed PMID: 10551163.

68: Zadeh HH, Nichols FC, Miyasaki KT. The role of the cell-mediated immuneresponse to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontitis. Periodontol 2000. 1999 Jun;20:239-88. Review. PubMed PMID:10522228.

69: Zadeh HH, Kreutzer DL. Evidence for involvement of superantigens in humanperiodontal diseases: skewed expression of T cell receptor variable regions bygingival T cells. Oral Microbiol Immunol. 1996 Apr;11(2):88-95. PubMed PMID:8941759.

70: Zadeh HH, Greiner DL, Wu DY, Tausche F, Goldschneider I. Abnormalities in theexport and fate of recent thymic emigrants in diabetes-prone BB/W rats.Autoimmunity. 1996;24(1):35-46. PubMed PMID: 8937686.

71: Zadeh HH, Goldschneider I. Demonstration of large-scale migration of corticalthymocytes to peripheral lymphoid tissues in cyclosporin A-treated rats. J ExpMed. 1993 Jul 1;178(1):285-93. PubMed PMID: 8315384; PubMed Central PMCID:PMC2191078.

72: Hosseinzadeh H, Goldschneider I. Recent thymic emigrants in the rat express a unique antigenic phenotype and undergo post-thymic maturation in peripherallymphoid tissues. J Immunol. 1993 Mar 1;150(5):1670-9. PubMed PMID: 8094727.

73: Goldschneider I, Hosseinzadeh H, Chen-Woan M. Short-term treatment of ratswith cyclosporin A causes the appearance of lymph node T cells that resemblecortical thymocytes. Transplant Proc. 1991 Feb;23(1 Pt 1):122-5. PubMed PMID:1990495.

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BOOK CHAPTERS

1. Zadeh, H. H. and Gil A. Coronally Positioned Flaps and Tunneling. In. Naris: Advances in Periodontal Surgery. Springer International Publishing AG 2019 ISBN:978-3-030-12309-3

2. Avila-Ortiz G. and Zadeh, H. H. Management of the Extraction Site: Socket Grafting. In: Nevins and Wang. Quintessence Publishing Co. 2019.

3. Zadeh, H. H., Anthony-Costandi, D., Sharifzadeh, N. Peri-implant Soft Tissue Augmentation. In. Fonseca: Oral and Maxillofacial Surgery. Elsevier Publishing. 2017.

4. Cooper, L and Zadeh H.H. Recognition of Risk Factors and Patient Assessment. In. Implant Esthetics. Springer International Publishing AG 2017

5. Borzabadi-Farahani A, Zadeh HH. ORTHODONTIC THERAPY IN IMPLANT DENTISTRY: ORTHODONTIC IMPLANT SITE DEVELOPMENT. Vertical Alveolar Ridge Augmentation in Implant Dentistry: SurgicalManual, First Edition. Edited by Len Tolstunov. 2016 JohnWiley & Sons, Inc. Published 2016 by John Wiley & Sons, Inc.

6. Zadeh HH. Image-Based Implant Therapy: Current Status and Future Perspectives. Osseointegration and Dental implants. 2008. Wiley-Blackwell.

7. Zadeh HH. Ästhetische Zahnmedizin. Edited by Josef Schmidseder. Georg Thieme Verlag. 2008. Ästhetische Zahnmedizin Ästhetik in der Implantologie. Page 281-314.

8. Slots J, Chen C, Zadeh HH. Microbial specificity and virulence factors in periodontitis. Quintessence, 2003.

ABSTRACT PUBLICATIONS

1. Zadeh, H., Chen-Woan, M., Goldschneider, I. 1991. Kinetics of appearance of T lymphocytes expressing cortical thymocyte markers in the lymph node of cyclosporin A-treated rats. FASEB J. 5(4):A731.

2. Zadeh, H., Goldschneider, I. 1992. Recent thymic emigrants express Thy1 and undergo postthymic maturation in the rat. FASEB J. 6(5):A1700.

3. Zadeh, H.H., Kreutzer, D.L. 1993. Analysis of Gingival T Cell Subsets Suggests Expansion by Superantigens. J. Dent. Res.

4. Zadeh, H.H., Peneguy, M., Minkin, C. 1994. Osteoclast enrichment of mouse bone marrow preparations with mAb 12F-magnetic beads. Am. Soc. Bone and Mineral Res. (Abstract #1765).

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5. Zadeh, H.H., Slots, J., Karimzadeh, K. and Kreutzer, D.L. 1995. A.actinomycetemcomitans stimulated T cells express dominance of a limited number of TCR V regions, akin to superantigen. J. Dent. Res. 74:125.

6. Kiai, K., Wager, K.A., Kreutzer, D.L. and Zadeh, H.H. 1995. Gingival T cells express the integrin CD103 identified with the monoclonal antibody HML-1. Int. Congress Immunol. (Abs # 3205).

7. Dersarkissian, C., Wager, K.A., Kreutzer, D.L., Slots, J. and Zadeh, H.H. 1995. Superantigenic properties of porphyromonas gingivalis: dominant expression of a limited number of TCR V regions by in vitro stimulated T cells Int. Congress Immunol. (Abs # 4276).

8. Karimzadeh, K. and Zadeh, H.H. 1995. Local perturbation of T cell receptor V repertoire among functional subsets of isolated gingival T cells in periodontitis suggests involvement of Superantigens. J. Dent. Res. 74:157.

9. Zadeh, H.H., Slots, J., and Kreutzer, D.L. 1996. Analysis of early responding T cells suggests expression of a superantigen by A.actinomycetemcomitans. J. Dent. Res. 75:157.

10. Park, K.E., Slots, J., Kreutzer, D.L. and Zadeh, H.H. 1996. A novel culture system for detecting early activation of responding T cells to superantigens. J. Dent. Res. 75:157.

11. Karimzadeh, K. and Zadeh, H.H. 1996. Local perturbation of T Cell receptor V repertoire among functional subsets of isolated gingival T cells in periodontitis suggests involvement of Superantigens. J. Dent. Res. 75:157.

12. Zadeh, H.H. and Wager, K. 1997. Expression of human mucosal-associated lymphocyte antigen (CD103) on gingival T cells suggests unique coming and/or differentiation. J. Dent. Res. 76: 350.

13. Nalbant, A. and Zadeh, H.H. 1998. Purification and characterization of superantigen(s) expressed by A.actinomycetemcomitans.. FASEB J. 12:LB129.

14. Wood, G., Tanavoli, S., Bughi, S. and Zadeh, H.H. 1998. Circadian rhythms of cytokine expression: possible regulatory role of cortisol and -endorphin. FASEB J. 12: LB130.

15. Tanavoli, S., Wood, G., Bughi, S. and Zadeh, H.H. 1998. The cytokine response of T cells to periodontal pathogens follows circadian rhythms: possible role of cortisol and -endorphin. J. Dent. Res. 77:982.

16. Daneshmand, N. Mercer, B. Minkin, C. and Zadeh, H.H. 1999. Soluble mediators released by mononuclear leukocytes in response to A.actinomycetemcomitans regulate osteoclast activity. J. Periodontol. 70:106.

17. Karimzadeh, K. and Zadeh, H.H. 1999. Skewing of the T cell receptor V repertoire in gingiva of periodontitis patients suggests the involvement of specific T cell subsets in periodontitis. J. Periodontol. 70:338.

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18. Moshrefi, A. and Zadeh, H.H. 1999. The kinetics of expression of T cells stimulatory molecule(s) by Actinobacillus actinomycetemcomitans J. Periodontol. 70:106.

19. Raschkovsky R. and H. H. Zadeh. 1999 Phenotypical Characterization of Intraepithelial Gingival T-Lymphocytes Suggests Their Active Involvement in Local Immune Response. J. Dent. Res. 78: 350.

20. Zadeh, H.H., Nalbant, A. and Tanavoli, S. 2000. In vitro activation of T cells with A. actinomycetemcomitans leads to apoptosis or anergy of most and differentiation into effectors of only a minor subset. J. Dent. Res. 79: 256.

21. Raschkovsky R. and H. H. Zadeh. 2000. Phenotypic and morphologic characterization of gingival intraepithelial T-lymphocytes (IEL). J. Periodontol. 71: 1915.

22. Zadeh, H.H. and Karimzadeh, K. 2000. T cell receptor V repertoire of individuals with and without periodontitis suggests developmental influences. J. Periodontol. 71: 1926-1927.

23. Nalbant, A. and Zadeh, H.H. 2001. Cellular and molecular mediators of Actinobacillus actinomycetemcomitans-induced T cells apoptosis. J. Dent. Res. 80: 532.

24. Nalbant, A. and Zadeh, H.H. 2001. Actinobacillus actinomycetemcomitans induces T cell apoptosis via Fas/FasL signaling pathway. J. Dent. Res. 80: 138.

25. Mena, J. and Zadeh, H.H., Chen, C. Identification of genotypic differences in two strains of Actinobacillus actinomycetemcomitans. J. Dent. Res. 81:A197.

26. Nalbant, A., Haghighatpour, M. and Zadeh, H.H. 2002. Activation of regulatory T cells by Actinobacillus actinomycetemcomitans is responsible for impaired cytokine expression. J. Dent. Res. 81:A312.

27. Zadeh, H.H. and Nalbant, A. 2003. Apoptotic activity of the GroEL-like protein isolated from Actinobacillus actinomycetemcomitans. J. Dent. Res.

28. Nalbant, A. and Zadeh, H.H. 2003. Actinobacillus actinomycetemcomitans-Induced T Cell Apoptosis Independent of Cytolethal Distending Toxin and Leukotoxin. J. Dent. Res.

29. You, HK, Zadeh, HH. Neural trans-differentiation of Mesenchymal Stem Cells Derived from Alveolar Bone. Astra World Congress. 2006 

30. Campos, M. Zadeh, HH. Microarray analysis of T-Cell function related gene expression in periodontal disease. J. Periodontol. 2006 

31. Owyoung, J., Zadeh, HH. Microarray analysis of apoptosis-related gene expression in periodontal disease. J. Periodontol. 2006o

32. Jamsheed, A., Zadeh, HH. Differences between peripheral blood gene expression by microarray in periodontal disease and healthy patients. Periodontol. 2006  

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