M.R. Abbaszadegan Page 1 of 26

CURRICULUM VITAE

MOHAMMAD R. ABBASZADEGAN, MT (ASCP), Ph.D.

Professor

Head, Medical Genetic Research Center (MGRC), School of Medicine,

Mashhad University of Medical Sciences

&

Director, Division of Human Genetics

Avicenna Research Institute

&

Adjunct Faculty at the Arizona State University & George Mason University

Address: Division of Human Genetics, Avicenna Research Institute

Mashhad University of Medical Sciences

Ferdosi Square, Bu-Ali Sq., Mashhad, Khorasan, Iran Postal Code: 9196773117

(98-511) 7112343, Fax: (98-511) 7112343, Email: abbaszadeganmr@mums.ac.ir

CERTIFICATION

Medical Geneticist: American Board of Medical Genetics, Board Eligible

Clinical Molecular Geneticist, National Human Genome Research Institute, NIH

Medical Technologist: American Society of Clinical Pathologist (ASCP)

Medical Laboratory Scientist: National Certifying Agency (NCA)

EDUCATION

8/90-5/95 Ph.D. in Pharmacology & Toxicology – Cancer Genetics

University of Arizona Medical Center, Tucson, Arizona 85721

Minor: Microbiology & Immunology

Major Advisor: William S. Dalton, M.D., Ph.D.

Dissertation: Molecular Mechanisms of Drug Resistance in Human Malignancies.

1/87-12/90 Master of Science in Applied Microbiology

Northern Arizona University, Flagstaff, Arizona 86011

Major Advisor: Emmanuel T. Akporiaye, Ph.D.

Thesis: Tumoricidal Activity of Tumor Infiltrating T-lymphocytes Against EMT6

(mammary carcinoma) Tumor Cells, Following the Injection of Viable or Irradiated

Tumor Cells

9/81-6/85 Bachelor of Science in Microbiology

University of Montana, Missoula, Montana 59801

PROFESSIONAL EXPERIENCE

M.R. Abbaszadegan Page 2 of 26

8/09-7/10 Adjunct Faculty at TGen and The Arizona State University (Sabbatical), The Translational

Genomics Research Institute (TGen), Phoenix, AZ 85004, Director: Jeff Trent, Ph.D.

7/03- 10/03 Fellowship –Diagnosis of Rare Genetic Diseases & their Prenatal Genetic Diagnosis,

GeneDx, Inc. DNA Diagnostic Institute affiliated with NIH, Director: Sherri Bale, Ph.D.,

FABCG.

1/98- 1/2000 Fellowship – Clinical Molecular Genetics, The American Board of Medical Genetics

NIH/ Georgetown / Children’s Medical Center Joint fellowship program

Program Director: Clair A. Francomano, M.D.

6/95- 11/97 Postdoctoral Fellow-Intramural Research Training Award (IRTA)

Diagnostic Development Branch

National Human Genome Research Institute, NIH, Bethesda, Maryland 20892

Advisor: Mark R. Hughes, M.D., Ph.D.

Project: Research and Development of new diagnostic assays for human genetic

diseases, Prenatal genetic diagnosis & Familial Breast Cancer

7/85-8/86 Medical Technology Internship Program

Bannock Regional Medical Center, Pocatello, Idaho 83204

Certificates: American Society of Clinical Pathologist (ASCP) & National Certifying

Agency (NCA)

RELEVANT WORK EXPERIENCE

8/2000-Now Assistant, Associate and now Professor, Medical Genetics

Head, Medical Genetics Research Center

Mashhad University of Medical Sciences

Mashhad, Iran

11/96- 8/98 Assistant Professor

Institute for Molecular & Human Genetics

Georgetown University Medical Center

3800 Reservoir Road, 4 Main, M4000

Washingtion D.C. 20007

6/95- 11/96 Postdoctoral Fellow

Diagnostic Development Branch

National Center for Human Genome Research, NIH, Bethesda, Maryland 20892

Principal investigator: Mark R. Hughes, M.D., Ph.D.

Project: Research and Development of new diagnostic assays for human

genetic diseases, Prenatal & Preimplantation genetic diagnosis & Familial

Breast Cancer

1/90-8/90 Research Assistant II

University of Arizona Medical Center, Tucson, Arizona 85721

Internal Medicine/Gastroenterology

Principal investigator: David Earnest, M.D.

M.R. Abbaszadegan Page 3 of 26

Project: Studying the mechanism of vitamin A potentiation of xenobiotic hepatotoxicity;

vitamin A activation of Kupffer cells in vitro and in vivo.

6/88-3/89 Medical Technologist

Public Health Service Indian Hospital, Tuba City, Arizona 86045 Laboratory Services

Laboratory Manager: Bruce Gardner

TEACHING EXPERIENCES

Courses taught:

Medical Genetics, Genetic Counseling Training Courses, Molecular and Cellular Biology, NIH training

courses for summer students and fellows, Laboratory Sciences, Immunobiology, General Biology, and

Bacteriology

AWARDS

6/1988 Sigma Xi, the Scientific Research Society

6/1995 National Institute of Health Intramural Research Training Award (IRTA)

3/1996 NIH Fellows Award for Research Excellence

12/2005 Khwarizmi First Award for Applied Medical Protocols (Congenital Adrenal Hyperplasia)

2013 3rd rank of the 19th Razi research festival on medical sciences

PROFESSIONAL SOCIETIES

American Society of Human Genetics

American Association for the Advancement of Science

Associate Member, American Association for Cancer Research

Student/Fellow Member, American Society for Microbiology

American Society of Medical Technologists

The Academy of Medical Sciences, I.R. of IRAN

SERVICE ACTIVITIES

Reviewer for the following Peer-Reviewed Journals:

World Journal of Gastroenterology, International Journal of Cancer, Archives of Iranian Medicine,

Eastern Mediterranean Health Journal, Genetic Testing, Iranian Journal of Public Health, Journal of

Research in Medical Sciences, Tumor Biology

Cancer therapeutics:

Preparation of DC-mRNA vaccine for treatment of Esophageal Squamous Cell Carcinoma (ESCC)

patients, DC-mRNA vaccine against gastric cancer stem cells, shRNA against MAML1, a notch

transactivation factor, master switch.

Biotechnology:

Designing, production and evalution of HTLVI, II diagnostic kit for detection of antibody against

HTLV virus, using HTLV recombinant Envelope proteins

Consulting for the following Institutions:

M.R. Abbaszadegan Page 4 of 26

Georgetown University Medical Center, Washington D.C.

GeneDx Inc., Gaithersburg, MD

Panacea Inc., Gaithersburg, MD

InnodevTech Inc., Phoenix, AZ

Metrics Instruments Inc., Phoenix, AZ

Civil, Environmental & Sustainable Engineering, Arizona State University, Tempe, AZ

GRANTS & Licensing a Technology

Primary Investigator:

1/15-7/17 MUMS research council and Presidential research award, Isolation of Gastric Cancer

stem cells (CSC) and preparation of DC-cell therapy using CSC mRNA.

6/14-6/16 MUMS research council, Isolation of ESCC Cancer stem cells and treating with

shRNA against MAML1, a notch signaling pathway master transactivator.

5/12-5/14 World Health Organization, EMGEN. Designing Conditional Sleeping Beauty

Transposition System for Modeling Esophageal Squamous Cell Carcinoma in Mouse

2/12-2/14 World Health Organization, EMGEN. Role of MAML1 in esophageal squamous

cell carcinoma cell biology

01/11-10/12 Mashhad University of Medical Sciences (MUMS) research council Joint Grant

Approval; Chimeric super-antigen synthesis for preparation of immunogenetherapy of Esophageal

Squamous Cell Carcinoma (ESCC) patients.

2/07-02/11 Digestive Disease Research Center, Tehran University of Medical Sciences (TUMS)

& Mashhad University of Medical Sciences (MUMS) research council Joint Grant Approval;

Preparation of DC-mRNA vaccine for treatment of Esophageal Squamous Cell Carcinoma (ESCC)

patients.

8/08-11/09 MUMS research council Grant; Evaluation of GST1 polymorphisms as biomarkers in

screening of ESCC.

5/06-6/08 MUMS research council Grant; Evaluation of Long DNA and BAT-26 Markers in

detection of colorectal cancer (CRC) by molecular analysis of patient's stool DNA in comparison with

normal subjects.

7/03-9/06 MUMS research council Grant; Molecular Analysis of CYP21A2 gene in 21-

hydroxylase deficiency and CYP11B in 11-hydroxylase deficiency in congenital adrenal hyperplasia

patients.

2/04-3/05 MUMS research council Grant; Mutation detection of TCIRG1 Gene in patients with

osteopetrosis.

4/00-5/04 National Medical Biotechnology Network Grant, Ministry of Health & Public

Services; Designing, production and evalution of HTLVI, II diagnostic kit for detection of antibody

against HTLV virus using HTLV recombinant Envelope proteins.

6/97-7/99 Department of Defense, Army Breast Cancer Grant - A case controlled study of

somatic changes in primary breast tumors from BRCA1 & BRCA2 mutation carriers compared to

sporadic breast tumors.

5/97-7/98 Transfer of technology “5’ Nuclease Allelic Discrimination Assay” - License

Agreement between Institute for Molecular & Human Genetics, Georgetown University Medical

Center and Institute of Medical Molecular Genetics, Berlin, Germany.

Co-Investigator:

M.R. Abbaszadegan Page 5 of 26

10/96-10/98 National Institute of Health, Screening for mutations in Breast and Ovarian Cancer

Susceptibility Genes, BRCA1 and BRCA2, in high risk families and psyco-social behavioral aspects of

this genetic testing (C. Lerman, P.I.).

6/97-7/99 Department of Defense, Army Breast Cancer Grant - Study of chromosomal

imbalances in microdissected breast tumor cells from a heterogenous population of cells derived from a

breast tumor section (B. Haddad, P.I.).

Research Projects in Iran*

*The projects that funding not specified was all approved by MUMS research council

Division of Human Genetic, Immunology Research Center, MUMS

Cancer Genetics:

1. Preparation of DC-mRNA vaccine for treatment of Esophageal Squamous Cell Carcinoma

(ESCC) patients (Joint Approval by Digestive Disease Research Center, Tehran University of

Medical Sciences & MUMS research council).

2. Evaluation of exfoliative cytology and new serum biomarkers in screening of ESCC (Approved

by national medical research council).

3. Evaluation of GST1 polymorphisms as biomarkers in screening of ESCC.

4. Evaluation of Long DNA and BAT-26 Markers in detection of colorectal cancer (CRC) by

molecular analysis of patient's stool DNA in comparison with normal subjects.

5. Evaluation of frequency of changes in P14 & P16 genes in CRC patients.

6. Prognostic Significance of Germ-line E-Cadherin Mutation in Familial Gastric Cancer.

7. Molecular analysis of Wnt signaling pathway in Gastric cancer.

8. Microsatellite analysis in CRC patients.

9. Study of the association of HPV infection and P53 mutation with ESCC.

10. Microsatellite markers analysis in endometrial & ovarian cancer.

11. Assessment of P53 mutation in pathological staging and surgical margins in squamous cell

carcinoma of the head and neck.

Medical Genetics:

1. Molecular Analysis of CYP21A2 gene in 21-hydroxylase deficiency and CYP11B in 11-

hydroxylase deficiency in congenital adrenal hyperplasia patients in Iran.

2. Friedreich Ataxia: Molecular detection of FRDA GAA repeats in proband from a family in

province of Khorasan.

3. Preimplantation Genetics Diagnosis of - thalassemia using single cell PCR techniques.

4. Carrier detection and prenatal diagnosis of Hemophilia A and Finding of their Common mutation

by Molecular Genetics in Khorasan province

5. Mutation detection of TCIRG1 Gene in patients with osteopetrosis by PCR & RT-PCR.

M.R. Abbaszadegan Page 6 of 26

6. Evaluation of HTLV-I tax polymorphism as a probable risk factor for HAM/TSP in Khorasanian

patients.

Biotechnology:

1. Designing, production and evalution of HTLVI, II diagnostic kit for detection of antibody against

HTLV virus using HTLV recombinant Envelope proteins.

Funded by National Medical Biotechnology Network

***************************************

GenBank new sequence submissions:

1. Homo sapiens perforin gene, intron 1 (AY489286.1)

2. Human T-lymphotropic virus 1 isolate MTA-1 from Iran truncated envelope glycoprotein gene, partial

cds (DQ911752.1)

3. Homo sapiens isolate patient 1 steroid 21-hydroxylase (CYP21A2) gene, exons 9, 10 and partial cds.

(EU236681)

4. Homo sapiens isolate patient 2 steroid 21-hydroxylase (CYP21A2) gene, exons 9, 10 and partial cds.

(EU236682)

5. Homo sapiens mitochondrial 11beta-hydroxylase (CYP11B1) gene, exons 7, 8 and partial cds; nuclear

gene for mitochondrial product.(EU236683)

6. Homo sapiens adenomatous polyposis coli gene, partial cds. (EU681189)

7. Homo sapiens beta-catenin gene, partial cds.(EU681190)

8. Homo sapiens adenomatous polyposis coli gene, partial cds. (EU681276)

9. Homo sapiens beta-catenin gene, partial cds. (EU681277)

10. Tetraogallus caspius isolate CS1 cytochrome b (cytb) gene, partial cds; mitochondrial.(EU106676)

11. Homo sapiens potassium channel inwardly rectifing subfamily J member 11 (KCNJ11) gene, complete

cds (GU170814.1).

12. Homo sapiens truncated mitochondrial cytochrome P450 11B1 (CYP11B1) gene, exon 2 and partial cds;

nuclear gene for mitochondrial product (GU201906.1)

BOOKS

Tafazoli AR, Abbaszadegan MR. Next Generation Sequencing Technologies in Medical

Genetics, C. Alexander Valencia, et al. Translated to Farsi, 2017.

Abbaszadegan MR, Ghazaee S, Keify F, Mirzaee F. Clinical Cytogenetics: Classical, Molecular

advances. (Farsi), 2012.

Abbaszadegan MR, Gholamin M, Invited Book Chapter: Human T-Cell Lymphotropic Virus

(HTLV-1) and Adult T-Cell Leukemia. Editors: Babusikova O, Dovat S, Payne KJ,: T-Cell

Leukemia (chapter2), October 2011.

M.R. Abbaszadegan Page 7 of 26

Abbaszadegan MR, Ghayour M: Genetic and Nutrition Chapter, Harrison’s Principle of Internal

Medicine, 16th Edition, Supervisors in Translation to Farsi, 2006

Ghazvini K, Rezaee AR, Mohammadian-Roshan G, Rezaee-Talab GH, Abbaszadegan MR:

Diagnostic Virology (Farsi), 2008

PUBLICATIONS Articles

Ardalan Khales, S., Abbaszadegan, M.R., Majd, A., Forghanifard, M. M. Linkage between EMT

and stemness state through molecular association between TWIST1 and NY-ESO1 in esophageal

squamous cell carcinoma. BiochimieVolume 163, August 2019, Pages 84-93

Moghbeli, M., Mosannen Mozaffari, H., Memar, B., Gholamin, M., Abbaszadegan, M.R. Role of

MAML1 in targeted therapy against the esophageal cancer stem cells. Journal of Translational

Medicine. Volume 17, Issue 1, 16 April 2019, Article number 126

Tafazoli, A., Behjati, F., Farhud, D.D., Abbaszadegan, M.R. Combination of genetics and

nanotechnology for down syndrome modification: A potential hypothesis and review of the

literature. Iranian Journal of Public Health.Volume 48, Issue 3, 12 March 2019, Pages 371-378

Shariat Razavi, S.M., Forghanifard, M.M., Kordi-Tamandani, D.M., Abbaszadegan, M.R.

MAML1 regulates EMT markers expression through NOTCH-independent pathway in breast

cancer cell line MCF7. Biochemical and Biophysical Research Communications

510(3), pp. 376-382

Bagheri, V., Abbaszadegan, M.R., Memar, B., Mahmoudian, R.A., Gholamin, M. Induction of T

cell-mediated immune response by dendritic cells pulsed with mRNA of sphere-forming cells

isolated from patients with gastric cancer. Life SciencesVolume 219, 15 February 2019, Pages 136-

143

Keyfi, F., Abbaszadegan, M.R., Sankian, M., Alijanpour, M., Varasteh, A. Mutation analysis of

genes related to methylmalonic acidemia: identification of eight novel mutations. Molecular

Biology ReportsVolume 46, Issue 1, 1 February 2019, Pages 271-285

Ghaemi, N., Ghahraman, M., Noroozi Asl, S., (...), Moghbeli, M., Abbaszadegan, M.R. Novel

DNA variation of GPR54 gene in familial central precocious puberty. Italian Journal of Pediatrics.

Volume 45, Issue 1, 11 January 2019, Article number 10

Moghbeli, M., Makhdoumi, Y., Soltani Delgosha, M., Abdollahi, A., Abbaszadegan, M.R.

ErbB1 and ErbB3 co-over expression as a prognostic factor in gastric cancer. Biological

research.Volume 52, Issue 1, 8 January 2019, Page 2

Forghanifard, M.M., Abbaszadegan, M.R., Moghbeli, M. Role of SIZN1 in esophageal squamous

cell carcinoma. Middle East Journal of Cancer, Volume 10, Issue 1, 1 January 2019, Pages 37-42

M.R. Abbaszadegan Page 8 of 26

Forghanifard, M.M., Naeimi Khorasanizadeh, P., Abbaszadegan, M.R., Javdani Mallak,

A., Moghbeli, M. Role of DIDO1 in Progression of Esophageal Squamous Cell Carcinoma. Journal

of Gastrointestinal Cancer2019

Golyan, F.F., Moghaddassian, M., Forghanifard, M.M., Mahmoudian, R.A., Abbaszadegan, M.R.

Whole Exome Sequencing Reveals a Novel Damaging Mutation in Human Fibroblast Activation

Protein in a Family with Esophageal Squamous Cell Carcinoma. Journal of Gastrointestinal

Cancer2019

Khorasani, Z.M., Bagheri, R.K., Yaghoubi, M.A., (...), Abbaszadegan, M.R., Sahebkar, A.

The association between serum irisin levels and cardiovascular disease in diabetic patients.

Diabetes and Metabolic Syndrome: Clinical Research and Reviews Volume 13, Issue 1,

January - February 2019, Pages 786-790

Vojdani, S., Milanizadeh, S., Molaei, F., (...), Talee, M.R., Abbaszadegan, M.R. Mutation

Screening of KCNQ1 and KCNE1 Genes in Iranian Patients With Jervell and Lange-Nielsen

Syndrome. Fetal and Pediatric Pathology 2019

Abbaszadegan, M.R., Moghbeli, M .Genetic and molecular origins of colorectal Cancer

among the Iranians: Diagnostic Pathology. Volume 13, Issue 1, 22 December 2018, Article

number 97. e

Keyfi, F.a,b,Ebrahimzadeh-Vesal, R.d,Zhiyan, N.b,e, Nayebi, M.f,Nasseri, M.b,

Abbaszadegan, M.R.,c. The relationship between MTHFR polymorphisms and abortion in

Iranian women. Gene ReportsVolume 13, December 2018, Pages 130-133

Khorashad, B.S.aRoshan, G.M.a, Reid, A.G.b,Aghili, Z.a,Moghadam, M.D.c,Khazai,

B.a,Hiradfar, M.d,Afkhamizadeh, M.e,Ghaemi, N.c,Talaei, A.a,Abbaszadegan, M.R.f

,Aarabi, A.f,Dastmalchi, S.g,Van de Grift, T.C.h,i, Childhood Sex-Typed Behavior and

Gender Change in Individuals with 46,XY and 46,XX Disorders of Sex Development: An

Iranian Multicenter Study(Article) Archives of Sexual Behavior, Volume 47, Issue 8, 1

November 2018, Pages 2287-229

Kassner, U.fb, Klose, G.fc, König, C.fd, König, W.ez, Otte, B.fe, Parhofer, K.ff, Schatz,

U.fa, Schmidt, N.ev, Steinhagen-Thiessen, E.fb, Vogt, A.ff, Antza, C.fi, Athyros, V.fi, Bilianou,

E.fj, Boufidou, A.fk, Chrousos, G.fl, Elisaf, M.fg, Garoufi, A.fm, Katsiki, N.fn, Kolovou,

G.fo, Kotsis, V.fi, Rallidis, L.fp, Rizos, C.fg, Skalidis, E.fq, Skoumas, I.fr, Tziomalos, K.fs,

Shawney, J.P.S.fw, Abbaszadegan, M.R.a, Overview of the current status of familial

hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies

Collaboration (FHSC) AtherosclerosisVolume 277, 10 October 2018, Pages 234-255

Abbaszadegan, M.R.a,Riahi signaling pathways as activators for epidermal growth factor receptor

in esophageal squamous cell carcinoma, A.b,Forghanifard, M.M.c,Moghbeli, M.d WNT and

NOTCH . Cellular and Molecular Biology LettersOpen AccessVolume 23, Issue 1, 3 September

2018, Article number 42

M.R. Abbaszadegan Page 9 of 26

Motamedi Rad, N.a,Rezaeishahmirzadi, M.b, Shakeri, S.b, Abbaszadegan, M.Rc, Shekari, M.d

Association of IL-1B+3954 and IL-1RN polymorphisms in chronic gastritis and peptic

ulcer(Article)Iranian Journal of Public HealthOpen AccessVolume 47, Issue 9, 1 September 2018,

Pages 1363-1369

Abbaszadegan, M.R,b,Taghehchian, N.,br,Li, L.c,Aarabi, A.a, Moghbeli, M.d Contribution of

KCTD12 to esophageal squamous cell carcinoma(Article)(Open Access) BMC Cancer, Volume 18,

Issue 1, 29 August 2018, Article number 853

Abbaszadegan, M.R.a,b,Taghehchian, N.a,Aarabi, A.b,Moghbeli, M.cMAEL Cancer-

Testis Antigen as a Diagnostic Marker in Primary Stages of Gastric Cancer with

Helicobacter pylori Infection. Journal of Gastrointestinal Cancer,2018.

Khaleghizadeh M, Forghanifard MM, Rad A, Farshchian M, Hejazi Z, Gholamin M, Memar

B , Abbaszadegan MR. “Ectopic Expression of Human DPPA2 Gene in ESCC Cell Line

Using Retroviral System”. Avicenna journal of medical biotechnology 10, no. 2 (2018):75.

Bitaraf SM, Mahmoudian RA, Abbaszadegan MR, Mohseni Meybodi A, Taghehchian N,

Mansouri A, Forghanifard MM, Memar B, Gholamin M. “Association of Two CD44

Polymorphisms with Clinical Outcomes of Gastric Cancer Patients”. Asian Pacific Journal

of Cancer Prevention 19, no. 5 (2018):1313-8.

Molaei F, Forghanifard MM, Fahim Y, Abbaszadegan MR. “Molecular Signaling in

Tumorigenesis of Gastric Cancer”. Iranian biomedical journal 22, no.4 (2018):217-30.

Bagheri V, Memar B, Momtazi AA, Sahebkar A, Gholamin M, Abbaszadegan MR.

“Cytokine networks and their association with Helicobacter pylori infection in gastric

carcinoma”. Journal of cellular physiology 233, no.4 (2018): 2791-803.

Bagheri V, Memar B, Behzadi R, Aliakbarian M, Jangjoo A, Bahar MM, Talebi S, Gholamin M,

Abbaszadegan MR. “Isolation and identification of chemotherapy‐enriched sphere‐forming cells

from a patient with gastric cancer”. Journal of cellular physiology. Journal of Cellular Physiology

233(10), pp. 7036-7046

Farshchian M, Matin MM, Armant O, Geerts D, Dastpak M, Nakhaei-Rad S, Tajeran M,

Jebelli A, Shahriyari M, Bahrami M, Fallah A, Yaghoobi V, Mirahmadi M, Abbaszadegan

MR, Bahrami AR. “Suppression of dsRNA response genes and innate immunity following

Oct4, Stella, and Nanos2 overexpression in mouse embryonic fibroblasts”. Cytokine.

(2018); 106:1-1.

Ebrahimzadeh-Vesal R, Hosseini S, Moghaddassian M, Abbaszadegan MR. “Identification

of novel missense HEXB gene mutation in Iranian-child with juvenile Sandhoff disease”.

Meta Gene 30, no.12 (2017):83-7.

Khalilipour N, Baranova A, Jebelli A, Heravi-Moussavi A, Bruskin S, Abbaszadegan MR.

“Familial esophageal squamous cell carcinoma with damaging rare/germline mutations in

M.R. Abbaszadegan Page 10 of 26

KCNJ12/KCNJ18 and GPRIN2 genes”. Cancer Genetics. (2017); doi:

10.1016/j.cancergen.2017.11.011. Epub 2017

Bagerabad MB, Tavakolian S, Abbaszadegan MR, Kerachian MA. “Promoter

Hypermethylation of the Eyes Absent 4 Gene is a Tumor-Specific Epigenetic Biomarker in

Iranian Colorectal Cancer Patients”. Acta Medica Iranica 56, no.1 (2018):21-7.

Tafazoli A, Eshraghi P, Pantaleoni F, Vakili R, Moghaddassian M, Ghahraman M, Muto V,

Paolacci S, Golyan FF, Abbaszadegan MR. Novel mutations and their genotype-phenotype

correlations in patients with Noonan syndrome, using next-generation sequencing. Adv Med

Sci. 2017 Sep 26; 63(1):87-93. doi: 10.1016/j.advms.2017.07.001. [Epub ahead of print]

Karami Madani G, Rad A, Molavi M, Ardalan Khales S, Abbaszadegan MR, Forghanifard

MM. Predicting the Correlation of EZH2 and Cancer Stem Cell Markers in Esophageal

Squamous Cell Carcinoma. J Gastrointest Cancer. (2017) doi: 10.1007/s12029-017-9985-y.

[Epub ahead of print]

Abbaszadegan MR, Moghbeli M. “Role of MAML1 and MEIS1 in Esophageal Squamous

Cell Carcinoma Depth of Invasion”. Pathol Oncol Res. (2017) doi: 10.1007/s12253-017-

0243-1. [Epub ahead of print]

Houshmand M, Abbaszadegan MR, Kerachian MA. “Assessment of Bone Morphogenetic

Protein 3 Methylation in Iranian Patients with Colorectal Cancer.” Middle East J Dig Dis 9,

no.3 (2017):158-163.

Moghbeli M, Naghibzadeh B, Ghahraman M, Fatemi S, Taghavi M, Vakili R,

Abbaszadegan MR. "Mutations in HNF1A Gene are not a Common Cause of Familial

Young-Onset Diabetes in Iran." Indian Journal of Clinical Biochemistry (2017): 1-5.

Forouzanfar, Narjes, Ancha Baranova, Saman Milanizadeh, Alireza Heravi-Moussavi, Amir

Jebelli, Abbaszadegan MR. "Novel candidate genes may be possible predisposing factors

revealed by whole exome sequencing in familial esophageal squamous cell carcinoma."

Tumor Biology 39, no. 5 (2017): 1010428317699115.

Zeynalzadeh M, Tafazoli A, Aarabi A, Moghaddassian M, Ashrafzadeh F, Houshmand M,

Taghehchian N, Abbaszadegan MR. “Four novel mutations of the BCKDHA, BCKDHB

and DBT genes in Iranian patients with syrup urine disease”. Journal of Pediatric

Endocrinology and Metabolism 31, no.2 (2018):205-212.

Izadpanah MH, Abbaszadegan MR, Fahim Y, Forghanifard MM. “Ectopic expression of

TWIST1 upregulates the stemness marker OCT4 in the esophageal squamous cell carcinoma

cell line KYSE30”. Cellular & molecular biology letters 22, no.1 (2017):33.

Maroofian R, Riemersma M, Jae LT, Zhianabed N, Willemsen MH, Wissink-Lindhout WM,

Willemsen MA, de Brouwer AP, Mehrjardi MY, Ashrafi MR, Kusters B, Kleefstra T,

Jamshidi Y, Nasseri M, Pfundt R, Brummelkamp TR, Abbaszadegan MR, Lefeber DJ, van

Bokhoven H. “B3GALNT2 mutations associated with non-syndromic autosomal recessive

M.R. Abbaszadegan Page 11 of 26

intellectual disability reveal a lack of genotype–phenotype associations in the muscular

dystrophy-dystroglycanopathies”. Genome medicine. 9, no.1 (2017):118.

Tafazoli, Alireza, Peyman Eshraghi, Zahra Kamel Koleti, Abbaszadegan MR. "Noonan

syndrome–a new survey." Archives Med Science: AMS 13, no. 1 (2017): 215.

Bidokhti, Mahnaz Hashemi, Abbaszadegan MR, Noorieh Sharifi, Soodabeh Abbasi Sani,

Mohammad Mahdi Forghanifard. "Contribution of MAML1 in esophageal squamous cell

carcinoma tumorigenesis." Annals of Diagnostic Pathology 27 (2017): 79-82.

Sheibani, Shoaleh, Reihaneh Alsadat Mahmoudian, Abbaszadegan MR, Jamshidkhan

Chamani, Bahram Memar, Mehran Gholamin. "Expression analysis of matrix

metalloproteinase-13 in human gastric cancer in the presence of Helicobacter Pylori

infection." Cancer Biomarkers 18, no. 4 (2017): 349-356.

Shirkani, Afshin, Atena Mansouri, Abbaszadegan MR, Reza Faridhosseini, Farahzad

Jabbari Azad, and Mehran Gholamin. "GATA3 Gene Polymorphisms Associated with

Allergic Rhinitis in an Iranian Population." Reports of Biochemistry & Molecular Biology 5,

no. 2 (2017): 97.

Abbaszadegan MR, Bagheri V, Mahya Shariat Razavi, Amir Abbas Momtazi, Amirhossein

Sahebkar, Mehran Gholamin. "Isolation, identification, and characterization of cancer stem

cells: a review." J cellular physiology 8(232) (2016).

Khorashad, Behzad S., Ghasem M. Roshan, Alistair G. Reid, Zahra Aghili, Mehran

Hiradfar, Mozhgan Afkhamizadeh, Ali Talaei, Azadeh Aarabi, Nosrat Ghaemi, Negin

taghehchian, Hedieh Saberi, Nazanin Farahi, Abbaszadegan MR. "Sexual orientation and

medical history among Iranian people with Complete Androgen Insensitivity Syndrome and

Congenital Adrenal Hyperplasia." Journal of psychosomatic research 92 (2017): 55-62.

Moghbeli, Meysam, Somaye Chavoshi, Mahmud Tavallaie, Ezzat Dadkhah, Reza

Raeissosadati, Moein Farshchian, Mohsen Towliat Kashani, Abbaszadegan MR. "Guanylyl

Cyclase C as a tumor marker for detection of circulating tumor cells in the peripheral blood

of colorectal cancer patients." International Journal of Cancer Therapy and Oncology 4, no.

4 (2016).

Sahebi, Reza, Mahshid Malakootian, Baharak Balalaee, Alireza Shahryari, Masoud

Khoshnia, Abbaszadegan MR, Abdolvahab Moradi, and Seyed Javad Mowla. "Linc-ROR

and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell

carcinoma." Iranian journal of basic medical sciences 19, no. 10 (2016): 1131.

Najafi M, Abbaszadegan MR, Abolfazl Rad, Mahtab Dastpak, Samaneh Boroumand-

Noughabi, Forghanifard MM. "Crosstalk between SHH and stemness state signaling

pathways in esophageal squamous cell carcinoma." Journal of cell communication and

signaling 11, no. 2 (2017): 147-153.

Khorashad, Behzad S., Zahra Aghili, Baudewijntje PC Kreukels, Mehran Hiradfar, Ghasem

M. Roshan, Mozhgan Afkhamizadeh, Abbaszadegan MR, Nosrat Ghaemi, Behnaz Khazai,

M.R. Abbaszadegan Page 12 of 26

and P. T. Cohen-Kettenis. "Psychosexual Outcome among Iranian Individuals With 5α-

Reductase Deficiency Type 2 and its Relationship With Parental Sexism." The Journal of

Sexual Medicine 13, no. 11 (2016): 1629-1641.

Keyfi F, Abbaszadegan MR, Arndt Rolfs, Slobodanka Orolicki, Morteza Moghaddassian,

Abdolreza Varasteh. "Identification of a novel deletion in the MMAA gene in two Iranian

siblings with vitamin B12-responsive methylmalonic acidemia." Cellular & Molecular

Biology Letters 21, no. 1 (2016): 4.

Forghanifard MM, Abolfazl Rad, Moein Farshchian, Maryam Khaleghizadeh, Mehran

Gholamin, Meysam Moghbeli, Abbaszadegan MR. "TWIST1 upregulates the MAGEA4

oncogene." Molecular carcinogenesis 56, no. 3 (2017): 877-885.

Nariman-Saleh-Fam Z, Bastami M, Somi MH, Behjati F, Mansoori Y, Daraei A, Saadatian

Z, Nariman-Saleh-Fam L, Mahmoodzadeh H, Makhdoumi Y, Tabrizi FV, Ebrahimi-Sharif

B, Hezarian A, Naghashi S, Abbaszadegan MR, Tavakkoly-Bazzaz J. “miRNA-Related

Polymorphisms in miR-423 (rs6505162) and PEX6 (rs1129186) and Risk of Esophageal

Squamous Cell Carcinoma in an Iranian Cohort”. Genetic testing and molecular biomarkers

21, no. 6 (2017):382-90.

Rad, Abolfazl, Saeed Esmaeili Dizghandi, Abbaszadegan MR, Negin Taghechian, Maryam

Najafi, Forghanifard MM. "SOX1 is correlated to stemness state regulator SALL4 through

progression and invasiveness of esophageal squamous cell carcinoma." Gene 594, no. 2

(2016): 171-175.

Moghbeli, Meysam, Abolfazl Rad, Moein Farshchian, Negin Taghehchian, Mehran

Gholamin, Abbaszadegan MR. "Correlation between Meis1 and Msi1 in esophageal

squamous cell carcinoma." Journal of gastrointestinal cancer 47, no. 3 (2016): 273-277.

Nariman-Saleh-Fam, Ziba, Milad Bastami, Mohammad Hossein Somi, Naser Samadi,

Abbaszadegan MR, Farkhondeh Behjati, Hamid Ghaedi, Javad Tavakkoly-Bazzaz, Andrea

Masotti. "In silico dissection of miRNA targetome polymorphisms and their role in

regulating miRNA-mediated gene expression in esophageal cancer." Cell Biochemistry and

Biophysics 74, no 4 (2016): 483-497.

Moghbeli, Meysam, Abbaszadegan MR, Ebrahim Golmakani, and Mohammad Mahdi

Forghanifard. "Correlation of Wnt and NOTCH pathways in esophageal squamous cell

carcinoma." Journal of cell communication and signaling 10, no. 2 (2016): 129-135.

Moaven, Omeed, Hamid Raziee, Wilbur Bowne, Abbaszadegan MR, and Bryan C. Fuchs.

"Disease Biomarkers in Gastrointestinal Malignancies." Disease Markers 2016 (2016).

Aghdam, Maryam Nasiri, Abbaszadegan MR, Alireza Tafazoli, Mohammad Aslzare, and

Zohreh Mosavi. "Presence of the RET Cys634Tyr mutation and Gly691Ser functional

polymorphism in Iranian families with multiple endocrine neoplasia type 2A." Hormones

(Athens, Greece) 15, no. 1 (2016): 65.

M.R. Abbaszadegan Page 13 of 26

Sedighi, Maryam., Seyye Amir Aledavood, Abbaszadegan MR, Bahram Memar, Mahdi

Montazer, Mohammad Rajabian, and Mehran Gholamin. "Matrix Metalloproteinase-13-A

Potential Biomarker for Detection and Prognostic Assessment of Patients with Esophageal

Squamous Cell Carcinoma." Asian Pacific journal of cancer prevention: APJCP 17, no. 6

(2016): 2781.

Forghanifard, Mohammad Mahdi, Elham Emami Vahid, Ezzat Dadkhah, Mehran Gholamin,

Samaneh Broumand Noghabi, Martha Ghahraman, Mehdi Farzadnia, Abbaszadegan MR.

"Loss of heterozygosity and microsatellite instability as predictive markers among Iranian

esophageal cancer patients." Iranian Journal of Basic Medical Sciences 19, no. 7 (2016):

726-733.

Abbasi Sani Soodabeh, Mohammad Mahdi Forghanifard, Noorieh Sharifi, Mahnaz Hashemi

Bidokhti, Alireza Jian Bagherpoor, Abbaszadegan MR. "Investigation of melanoma-

associated antigen A4 cancer/testis antigen clinical relevance in esophageal squamous cell

carcinoma." Journal of Cancer Research and TherapeuticsOpen AccessVolume 14, Issue 5,

July-September 2018, Pages 1059-1064

Mahmoudian, Reihaneh Alsadat, Abbaszadegan MR, Mehran Gholamin. "Applying

Subtractive Hybridization Technique to Enrich and Amplify Tumor-Specific Transcripts of

Esophageal Squamous Cell Carcinoma." Pathology & Oncology Research 23, no. 2 (2017):

271-279.

Forghanifard MM, Sima Ardalan Khales, Moein Farshchian, Abolfazl Rad, Masoud

Homayouni-Tabrizi, Abbaszadegan MR. "Negative regulatory role of TWIST1 on SNAIL

gene expression." Pathology & Oncology Research 23, no. 1 (2017): 85-90.

Ghahraman M, Abbaszadegan MR, Vakili R, Hosseini S, Fardi Golyan F, Ghaemi N,

Forghanifard MM. "Identification of four novel mutations of the WFS1 gene in Iranian

Wolfram syndrome pedigrees." Acta diabetologica 53, no. 6 (2016): 899-904.

Moghbeli, Meysam, Ali Sadrizadeh, Mohammad Mahdi Forghanifard, Hooman Mosannen

Mozaffari, Ebrahim Golmakani, Abbaszadegan MR. "Role of Msi1 and PYGO2 in

esophageal squamous cell carcinoma depth of invasion." Journal of cell communication and

signaling 10, no. 1 (2016): 49-53.

Mallak, Afsaneh Javdani, Abbaszadegan MR, Pegah Naeemi Khorasanizadeh, and

Mohammad Mahdi Forghanifard. "Contribution of EVX1 in Aggressiveness of Esophageal

Squamous Cell Carcinoma." Pathology & Oncology Research 22, no. 2 (2016): 341-7.

Rad A, Farshchian M, Forghanifard MM, Matin MM, Bahrami AR, Dirk Geerts, A’rabi A,

Memar B, Abbaszadegan MR. "Predicting the molecular role of MEIS1 in esophageal

squamous cell carcinoma." Tumor Biology 37, no. 2 (2016): 1715-25.

Barooei, Roghayeh, Reihaneh Alsadat Mahmoudian, Abbaszadegan MR, Atena Mansouri,

and Mehran Gholamin. "Evaluation of thymic stromal lymphopoietin (TSLP) and its

correlation with lymphatic metastasis in human gastric cancer." Medical Oncology 32, no. 8

(2015): 217.

M.R. Abbaszadegan Page 14 of 26

Khaleghizadeh M, Abbaszadegan MR, Gholamin M, Forghanifard MM. "Isolation and

Cloning of Human Developmental Pluripotency Aassociated-2 Cancer Testis Gene." ژنتیک .در هزاره سوم

Moghbeli, Meysam, Mohammad Mahdi Forghanifard, Ali Sadrizadeh, Hooman Mosannen

Mozaffari, Ebrahim Golmakani, Abbaszadegan MR. "Role of Msi1 and MAML1 in

Regulation of Notch Signaling Pathway in Patients with Esophageal Squamous Cell

Carcinoma." Journal of gastrointestinal cancer 46, no. 4 (2015): 365-9.

Haghnejad L, Emamalizadeh B, Jamshidi J, Bidoki AZ, Ghaedi H, Ahmadi E, Abdollahi S,

Shahmohammadibeni N, Taghavi S, Fazeli A, Motallebi M, Zarneh AE,

Mohammadihosseinabad S, Abbaszadegan MR, Torkamandi S, Gavenaroudi MA, Pedram

N, Shahidi GA, Tafakhori A, Darvish H, Movafagh A. Variation in the miRNA-433 binding

site of FGF20 is a risk factor for Parkinson's disease in Iranian population. J Neurol Sci. 15;

355(2015):72-4.

Masoud Homayouni-Tabrizi, Ahmad Asoodeh, Abbaszadegan MR, Khadijeh

Shahrokhabadi, and Mahboobeh Nakhaie Moghaddam. "An identified antioxidant peptide

obtained from ostrich (Struthio camelus) egg white protein hydrolysate shows wound

healing properties." Pharmaceutical biology 53, no. 8 (2015): 1155-62.

Saeedeh Ghazaey, Fatemeh Keify, Farzaneh Mirzaei, Masumeh Maleki, Semiramis Tootian,

Mitra Ahadian, Abbaszadegan MR. "Chromosomal analysis of couples with repeated

spontaneous abortions in northeastern Iran." International journal of fertility & sterility 9,

no. 1 (2015): 47.

Mahmoudian, Reihaneh, Abbaszadegan MR, Atena Mansouri, and Mehran Gholamin.

"Amplification of Tumor Transcripts from Limited Quantity of Esophageal Squamous Cell

Carcinoma Tissue Samples." American Journal of Cancer Science 4, no. 1 (2015): 54-62.

Mehran Gholamin, Ali Bazi, Abbaszadegan MR. "Idiopathic lymphocytopenia." Current

opinion in hematology 22, no. 1 (2015): 46-52.

Forghanifard MM, Taleb S, Abbaszadegan MR. "Notch Signaling Target Genes are

Directly Correlated to Esophageal Squamous Cell Carcinoma Tumorigenesis." Patholgy &

Oncology Research. 21, no. 2 (2015):463-7.

Atena Mansouri, Foroughmand AM, Abbaszadegan MR, Bahram Memar, Reyhaneh

Mahmoodian, Mehran Gholamin; Expression analysis of CD44 isoforms S and V3, in

patients with esophageal squamous cell carcinoma. Iran J Basic Med Sci. 18, no. 4 (2015):

380-4.

Homayouni-Tabrizi, Masoud, Ahmad Asoodeh, Abbaszadegan MR, Khadijeh

Shahrokhabadi, Mahboobeh Nakhaei Moghaddam. “Identification of New Angiotansin-1

Converting Enzyme Inhibitory Peptide from Ostrich Egg White Protein Hydrolysate.”

Journal of Isfahan Medical School 32, no 301 (2014): 1-13

M.R. Abbaszadegan Page 15 of 26

Torkamandi S, Meysam Moghbeli, Moein Farshchian, Abolfazl Rad, Abbaszadegan MR.

"Role of Brg1 in progression of esophageal squamous cell carcinoma." Iranian journal of

basic medical sciences 17, no. 11 (2014): 912.

Zand-Karimi MR, Reza Faridhosseini, Abbaszadegan MR, Afshin Shirkani, Anali Riyahi,

Mehdi Montazar, Gholamin M. "Association of ADAM33 gene polymorphisms with

allergic asthma." Iranian Journal of Basic Medical Sciences 17, no. 9 (2014): 716-721.

Mansouri A, Abbaszadegan MR, Jamshid Sorouri Khorashad, Bahram Memar and Mehran

Gholamin. “The expression levels of CD44V6 are correlated with tumor invasion in

esophageal squamous cell Carcinoma patients.” afinidad 80, no. 574 (2014): 1186-1190.

Mansouri A, Abbaszadegan MR, Mehran Gholamin. "A Review on the Biology of Cancer

Stem Cells." Stem Cell Discovery 4, no. 04 (2014): 83.

Forghanifard MM, Mehran Gholamin, Omeed Moaven, Moein Farshchian, Martha

Ghahraman, Amir Aledavood, Abbaszadegan MR. "Neoantigen in esophageal squamous

cell carcinoma for dendritic cell-based cancer vaccine development." Medical Oncology 31,

no. 10 (2014): 191.

Sima Ardalan Khales, Abbaszadegan MR, Abbas Abdollahi, Reza Raeisossadati, Mohsen

Fallah Tousi, and Mohammad Mahdi Forghanifard. "SALL4 as a new biomarker for early

colorectal cancers." Journal of cancer research and clinical oncology141, no.2 (2014):229-35.

Taleb S, Abbaszadegan MR, Meysam Moghbeli, Nasim Hayati Roudbari, Forghanifard

MM. "HES1 as an Independent Prognostic Marker in Esophageal Squamous Cell

Carcinoma." Journal of gastrointestinal cancer 45, no. 4 (2014): 466-471.

Meysam Moghbeli, Faezeh Moghbeli, Mohammad Mahdi Forghanifard, Abbaszadegan

MR. "Cancer stem cell detection and isolation." Medical Oncology 31, no. 9 (2014): 69.

Kolsoum Rezaie Kahkhaie, Omeed Moaven, Abbaszadegan MR, Mehdi Montazer, and

Mehran Gholamin. "Specific MUC1 splice variants are correlated with tumor progression in

esophageal cancer." World Journal of surgery 38, no. 8 (2014): 2052-2057.

Mahdi Daliri, Abbaszadegan MR, Mostafa Mehrabi Bahar, Azadeh Arabi, Mona

Yadollahi, Azar Ghafari, Negin Taghehchian, and Seyed Rasoul Zakavi. "The role of BRAF

V600E mutation as a potential marker for prognostic stratification of papillary thyroid

carcinoma: a long-term follow-up study." Endocrine research 39, no. 4 (2014): 189-193.

Forghanifard MM, Ardalan Khales S, Javdani-Mallak A, Rad A, Farshchian M,

Abbaszadegan MM. "Stemness state regulators SALL4 and SOX2 are involved in

progression and invasiveness of esophageal squamous cell carcinoma." Medical Oncology

31, no. 4 (2014): 922.

Raeisossadati R, Abbaszadegan MR, Meysam Moghbeli, Alireza Tavassoli, Alexandre

Hiroaki Kihara, and Mohammad Mahdi Forghanifard. "Aberrant expression of DPPA2 and

M.R. Abbaszadegan Page 16 of 26

HIWI genes in colorectal cancer and their impacts on poor prognosis." Tumor Biology 35,

no. 6 (2014): 5299-5305.

Meysam Moghbeli, Mohammad Mahdi Forghanifard, Azadeh Aarabi, Akram Mansourian,

Abbaszadegan MR. "Clinicopathological sex-related relevance of Musashi1 mRNA

expression in esophageal squamous cell carcinoma patients." Pathology & Oncology

Research 20, no. 2 (2014): 427-433.

Moghaddasian M, Hamidreza Arab, Ezzat Dadkhah, Hamidreza Boostani, Azam Rezaei

Babak, Abbaszadegan MR. "Protein modeling of cathepsin C mutations found in Papillon–

Lefèvre syndrome." Gene 538, no. 1 (2014): 182-187.

Farzin Heravi, Abbaszadegan MR, Mohsen Merati, Nadia Hasanzadeh, Ezzat Dadkhah,

and Farzaneh Ahrari. "DNA Damage in Oral Mucosa Cells of Patients with Fixed

Orthodontic Appliances." Journal of dentistry (Tehran, Iran) 10, no. 6 (2013): 494.

Sahar Shekouhi, Fatemeh Baghbani, Mohammad Hasanzadeh Nazar-Abadi, Tayebeh

Hamzehloie, Abbaszadegan MR, Nafiseh Saghafi, Reza Raoofian et al. "Identification of

Xq22. 1-23 as a region linked with hereditary recurrent spontaneous abortion in a family."

Iranian Journal of Reproductive Medicine 11, no. 8 (2013): 659.

Moghbeli M, Moaven O, Memar B, Raziei HR, Aarabi A, Dadkhah E, Forghanifard MM,

Manzari F, Abbaszadegan MR. “Role of hMLH1 and E-cadherin promoter methylation in

the gastric cancer progression.” J Gastrointestinal cancer 45, no. 1 (2013):40-47.

Simin Mohseni, Abbaszadegan MR, Bahram Memar, Akram Mansourian, and Mehran

Gholamin. "Expression analysis of histidine decarboxylase in esophageal squamous cell

carcinoma patients." Annals of Biological Research, no. 4 (2013): 36-40

Saeedeh Ghazaey, Farzaneh Mirzaei, Mitra Ahadian, Fatemeh Keifi, Tootian Semiramis,

Abbaszadegan MR. "Pattern of chromosomal aberrations in patients from north East iran."

Cell Journal (Yakhteh) 15, no. 3 (2013): 258.

Hossein Naseh, Bahram Memar, Reza Bagheri, Mehdi Montazer, Abbaszadegan MR. "A

Cancer-Array Approach Elucidates the Immune Escape Mecha-nism and defects in the DNA

Repair System in Esophageal Squa-mous Cell Carcinoma." Archives of Iranian medicine 16,

no. 8 (2013): 463.

Moghbeli M, Abbaszadegan MR, Farshchian M, Montazer M, Raeisossadati R, Abdollahi

A, Forghanifard MM. "Association of PYGO2 and EGFR in esophageal squamous cell

carcinoma." Medical Oncology 30, no. 2 (2013): 1-9.

Forghanifard MM, Moghbeli M, Raeisossadati R, Tavassoli A, Javdani Mallak A,

Boroumand-Noughabi S, Abbaszadegan MR. "Role of SALL4 in the progression and

metastasis of colorectal cancer." J Biomed Sci 20, no. 6 (2013): 922.

Nosrat Ghaemi, Martha Ghahraman, Abbaszadegan MR, Alireza Baradaran-Heravi, and

Rahim Vakili. "Novel Mutation in the SLC19A2 Gene in an Iranian Family with Thiamine-

M.R. Abbaszadegan Page 17 of 26

Responsive Megaloblastic Anemia: A Series of Three Cases." Journal of clinical research in

pediatric endocrinology 5, no. 3 (2013): 199.

Meysam Moghbeli, Faezeh Moghbeli, Mohammad Mahdi Forghanifard, Ali Garayali,

Abbaszadegan MR. "Cancer stem cell markers in esophageal cancer." American Journal of

Cancer Science 2, no. 1 (2013): 37-50.

Abbaszadegan MR, Soolmaz Hassani, Rahim Vakili, Mohammad Reza Saberi, Alireza

Baradaran-Heravi, Azadeh A’rabi, Mahin Hashemipour et al. "Two novel mutations in

CYP11B1 and modeling the consequent alterations of the translated protein in classic

congenital adrenal hyperplasia patients." Endocrine 44, no. 1 (2013): 212-219.

Houshang Rafatpanah, Abdolrahim Rezaee, Mohammad Mehdi Etemadi, Reza Farid

Hosseini, Bita Khorram, Leila Afsahr, Graham Taylor, Naser Mokhber, Mahmoud

Mahmoudi, Abbaszadegan MR and et al. "The impact of interferon-alpha treatment on

clinical and immunovirological aspects of HTLV-1-associated myelopathy in northeast of

Iran." Journal of neuroimmunology 250, no. 1 (2012): 87-93.

Nosrat Ghaemi, Martha Ghahraman, Abbaszadegan MR, Alireza Baradaran, and Rahim

Vakili. "Novel mutation in the SLC19A2 gene in Thiamine-responsive megaloblastic

anemia (Rogers’ syndrome)." Iranian Journal of Neonatology 1, no. 3 (2012): 30-35.

Rahim Vakili, Martha Ghahraman, Nosrat Ghaemi, Batool Faraji, Mahin Hashemi poor, Elham

Ahmadi, Abbaszadegan MR, Masumeh Saeidi, and Bahram Naghibzadeh. "Clinical and

Molecular Genetic Analysis of Iranian Neonatal Diabetic Cases Demonstrating Mutations in

KCNJ11 gene." Iranian Journal of Neonatology Vol 3, no. 2 (2012): 85-90.

Nosrat Ghaemi, Rahim Vakili, Daniel Zamanfar, Abaszadegan MR, Marta Ghahraman, and

Benyamin Mohseni Saravi. "Roger’s Syndrome and Report of 3 Cases in Children." J

Mazandaran Univer Med Sciences, no. 89 (2012):27-31.

Nosrat Ghaemi, Samaneh Noroozi Asl, Abbaszadegan MR, Marta Ghahraman, and Rahim

Vakili. "GPR54 Gene Mutations in Iranian Girls with Central Familial Precocious Puberty."

Iranian Journal of Obstetrics, Gynecology & Infertility 15, no. 28 (2012): 31-33.

Forghanifard MM, Jafar Amani, Elaheh Gheybi, Abbaszadegan MR. "In silico analysis of

chimeric polytope of cancer/testis antigens for dendritic cell-based immune-gene therapy

applications." Gene Therapy and Molecular Biology 14 (2012): 87-96.

Ezzat Dadkhah, Masood Ziaee, Mohammad Hossein Davari, Toba Kazemi, Abbaszadegan

MR. "Informative STR Markers for Marfan Syndrome in Birjand, Iran." Iranian journal of

basic medical sciences 15, no. 5 (2012): 1020.

Shokoufeh Bonakdaran, Abbaszadegan MR, Ezzat Dadkhah, and Mohammad Khajeh

Dalouie. "Vitamin D receptor gene polymorphisms in type 1 diabetes mellitus: a new pattern

from Khorasan province, Islamic Republic of Iran." Eastern Mediterrian Health Journal, no.

18 (2012): 614-619

M.R. Abbaszadegan Page 18 of 26

Keify F, Narges Zhiyan, Farzaneh Mirzaei, Semiramis Tootian, Saeedeh Ghazaey,

Abbaszadegan MR. "Two novel familial balanced translocations t (8; 11) (p23; q21) and t

(6; 16) (q26; p12) implicated in recurrent spontaneous abortion." Archives of Iranian

Medicine 15, no. 4 (2012): 249.

Meysam Moghbeli, Mahmood Maleknejad, Azadeh Arabi, Abbaszadegan MR. "Mutational

analysis of uroporphyrinogen III cosynthase gene in Iranian families with congenital

erythropoietic porphyria." Molecular biology reports 39, no. 6 (2012): 6731-6735.

Forghanifard MM, Omeed Moaven, Moein Farshchian, Mehdi Montazer, Reza

Raeisossadati, Abbas Abdollahi, Meysam Moghbeli, Taher Nejadsattari, Kazem Parivar,

Abbaszadegan MR. "Expression analysis elucidates the roles of MAML1 and Twist1 in

esophageal squamous cell carcinoma aggressiveness and metastasis." Annals of surgical

oncology 19, no. 3 (2012): 743-749.

Moghbeli M, Moaven O, Dadkhah E, Farzadnia M, Roshan NM, Asadzadeh-Aghdaee H,

Mehrabi Bahar M, Raeisossadati R, Forghanifard MM, Bakhtiari, Baradaran Heravi A,

Abbaszadegan MR. "High frequency of microsatellite instability in sporadic colorectal

cancer patients in Iran." Genet Mol Res 10, no. 4 (2011): 3520-9.

Forghanifard MM, Gholamin M, Farshchian M, Moaven O, Memar B, Forghani MN,

Dadkhah E, Naseh H, Moghbeli M, Raeisossadati R, Abbaszadegan MR. "Cancer-testis

gene expression profiling in esophageal squamous cell carcinoma: identification of specific

tumor marker and potential targets for immunotherapy." Cancer biology & therapy 12, no. 3

(2011): 191-197.

Reza Raeisossadati, Moein Farshchian, Azita Ganji, Alieza Tavassoli, Arash Velayati, Ezzat

Dadkhah, Somaye Chavoshi, Mostafa Mehrabi Bahar, Bahram Memar, Mohammad Taghi

Rajabi Mashhadi, Hossein Naseh, Mohammad Mahdi Forghanifard, Meysam Moghbeli,

Omeed Moaven, Abbaszadegan MR. "Quantitative analysis of TEM-8 and CEA tumor

markers indicating free tumor cells in the peripheral blood of colorectal cancer patients."

International J colorectal disease 26, no. 10 (2011): 1265-1270.

Abbaszadegan MR, Fatemeh Keify, Farah Ashrafzadeh, Moein Farshchian, Khadivi Zand

Farhad, Mohammad Naser Teymoorzadeh, Faezeh Mojahedi, Mitra Ahadian and Reza

Ebrahimzadeh. "Gene dosage analysis of proximal spinal muscular atrophy carriers using

real-time PCR." Archives of Iranian medicine 14, no. 3 (2011): 188.

Amir Asnaashari, Mohammad Towhidi, Reza Farid-Hosseini, Abbaszadegan MR, Davood

Attaran, Seiedeh Sedigheh Fatemi, and Atefeh Amiri Darban. "Evaluation of Polymerase

Chain Reaction for Diagnosis of “Tuberculous Pleurisy”." Tanaffos 10, no. 1 (2011): 12.

Sahar Shekouhi, Majid Mojarrad, Hasanzadeh Nazar-Abadi M, Tayebeh Hamzeh-loui,

Abbaszadegan MR, Reza Raoofian, Nafiseh Saghafi, and Fatemeh Baghbani. "Tracking of

M.R. Abbaszadegan Page 19 of 26

involved loci in recurrent abortion located on X chromosome in women with X linked

idiopathic recurrent spontaneous abortion." Clinical Biochemistry 44, no. 13 (2011): 286.

Noushin Taghavi, Firouzeh Biramijamal, Masoud Sotoudeh, Omeed Moaven, Hooman

Khademi, Abbaszadegan MR, Malekzadeh R. "Association of p53/p21 expression with

cigarette smoking and prognosis in esophageal squamous cell carcinoma patients." World

journal of gastroenterology: World J Gastroent 16, no. 39 (2010): 4958.

Mehran Gholamin, Omeed Moaven, Moein Farshchian, Mahmoud Mahmoudi, Mojtaba

Sankian, Bahram Memar, Mohammad Naser. Forghani, Reza Malekzadeh, Mohammad

Taher Rajabi-Mashhadi, Abbaszadegan MR. "Induction of cytotoxic T lymphocytes

primed with tumor RNA-loaded dendritic cells in esophageal squamous cell carcinoma:

preliminary step for DC vaccine design." BMC cancer 10, no. 1 (2010): 261.

Noushin Taghavi, Masoud Sotoudeh, Firouzeh Biramijamal, Abbaszadegan MR, Hooman

Khademi, Masoud Sotoudeh, Shahrouz Khoshbakht, and Reza Malekzadeh. "P21

(waf1/cip1) gene polymorphisms and possible interaction with cigarette smoking in

esophageal squamous cell carcinoma in northeastern Iran: a preliminary study." Archives of

Iranian medicine 13, no. 3 (2010): 235.

Omeed Moaven, Hamid Reza Raziee, Hamid Reza Sima, Azita Ganji, Reza Malekzadeh,

Azadeh A’rabi, Abbas Abdollahi, Bahram Memar, Masoud Sotoudeh, Hossein Naseh,

Hamid Nekoui, Adeleh Razavipour, Mehran Gholamin, Ezzat Dadkhah, Moein Farshchian,

Abbaszadegan MR. "Interactions between Glutathione-S-Transferase M1, T1 and P1

polymorphisms and smoking, and increased susceptibility to esophageal squamous cell

carcinoma." Cancer epidemiology 34, no. 3 (2010): 285-290.

Noushin Taghavi, Firouzeh Biramijamal, Masoud Sotoudeh, Hooman Khademi, Reza

Malekzadeh, Omeed Moaven, Bahram Memar, Azadeh A'rabi, Abbaszadegan MR.

"P16INK4a hypermethylation and p53, p16 and MDM2 protein expression in esophageal

squamous cell carcinoma." BMC cancer 10, no. 1 (2010): 138.

Gholamin M, Moaven O, Farshchian M, Rajabi MT, Mahmoudi M, Sankian M, Sazgarnia

A, Ghahreman M, Abbaszadegan MR. "Highly efficient transfection of dendritic cells

derived from esophageal squamous cell carcinoma patient: optimization with green

fluorescent protein and validation with tumor RNA as a tool for immuno-genetherapy." Iran

J Biotechnol 8 (2010): 121-126.

Mitra Naseri, Gian Marco Ghiggeri, Gianluca Caridi, Abbaszadegan MR. "Five cases of

severe vesico-ureteric reflux in a family with an X-linked compatible trait." Pediatric

Nephrology 25, no. 2 (2010): 349-352.

Abbaszadegan MR, Hamid Asadzadeh Aghdayi, Forough Rastin, Ezzat Dadkhah, Maryam

Lotfalizadeh, Nema Mohamadian Roshan, Mahdi Farzadnia, Arash Velayati, and Azadeh

A'rabi. "Microsatellite Instability in Young Women with Endometrioid type Endometrial

Cancer." Iranian Journal of Public Health 38, no. 3 (2009): 24-30.

M.R. Abbaszadegan Page 20 of 26

Ameri, A., A. Alidousti, K. M. Sheibani, A. G. Motlagh, N. Valaei, M. H. Emranpour,

Abbaszadegan MR, Y. Hosseini, and M. Parvin. "Probing the relation between gene

promoters hypermethylation of RARB and p16 among patients with prostatic cancer of

different prognosis." Pejouhandeh 13, no. 6 (2009): 469-474.

Mohammad Reza Zali, Omeed Moaven, Hamid Asadzadeh Aghdaee, Kamran

Ghafarzadegan, Khadijeh Jami Ahmadi, K, Mehdi Farzadnia, Azadeh Arabi, Abbaszadegan

MR. “Clinicopathological significance of E-cadherin, beta-catenin and p53 expression in

gastric adenocarinoma.” J Res Med Sci 14, no. 4 (2009): 239-247.

Mehran Gholamin, Omeed Moaven, Bahram Memar, Moein Farshchian, Hossein Naseh,

Reza Malekzadeh, Masoud Sotoudeh, Mohammad Taghi Rjabi Mashhadi Mohammad Naser

Forghani, Farid Farokhi, Abbaszadegan MR. "Overexpression and interactions of

interleukin-10, transforming growth factor β, and vascular endothelial growth factor in

esophageal squamous cell carcinoma." World journal of surgery 33, no. 7 (2009): 1439-

1445.

Abbaszadegan MR, Omeed Moaven, Hamid Reza Sima, Kamran Ghafarzadegan, Azadeh

A'rabi, Mohammad Naser Forghani, Hamid Reza Raziee et al. "p16 promoter

hypermethylation: a useful serum marker for early detection of gastric cancer." World

journal of gastroenterology: WJG 14, no. 13 (2008): 2055.

Abbaszadegan MR, Alireza Modarresi, Farhad Khadivi-Zand, Arash Velayati: “Rare gross

deletion in T-cell immune regulator-1 gene in Iranian family with infantile malignant

osteopetrosis.” Saudi Med J 29, no 10, (2008): 1494-1496.

Abbaszadegan MR, Narges Jafarzadeh, Mojtaba Sankian, AbdolReza Varasteh, Mahmoud

Mahmoudi, Majid Sadeghizadeh, Fatemeh Khatami, and Neema Mehramiz. "Truncated

MTA-1: a pitfall in ELISA-based immunoassay of HTLV-1 infection." BioMed Research

International, (2008).

Mohammad Hassan Khazai, Jalil Tavakkol Afshari, Bahram Khazai, Javad Akbarzadeh,

Ladan Khazai, AbbaszadeganMR, Farhad Khadivizand. “IL-4 and interferon gama in

recently diagnosed type-1 diabetes, a case control study.” ARYA Atherosclerosis Journal 3,

no. 1, (2007): 1-7

Tooka Banaei, Darush Farrokh-Tehrani, Abbaszadegan MR. “The Genetics of Age Related

Macular Degeneration.” Bina J Ophthalmol 13, no. 1, (2007): 104-118

Alireza Baradaran‐Heravi, Rahim Vakili, Tiina Robins, Jonas Carlsson, Nosrat Ghaemi,

Azadeh A’rabi, Abbaszadegan MR. "Three novel CYP21A2 mutations and their protein

modelling in patients with classical 21‐hydroxylase deficiency from northeastern Iran."

Clinical endocrinology 67, no. 3 (2007): 335-341.

Abbaszadegan MR, Alireza Tavasoli, Arash Velayati, Hamid Reza Sima, Hassan

Vosooghinia, Mehdi Farzadnia, Hamid Asadzedeh, Mehran Gholamin, Ezzat Dadkhah, and

Azadeh Aarabi. "Stool-based DNA testing, a new noninvasive method for colorectal cancer

screening, the first report from Iran." World journal of gastroenterology: World J Gastr 13,

no. 10 (2007): 1528-1533.

M.R. Abbaszadegan Page 21 of 26

Abbaszadegan MR, Arash Velayati, Alireza Tavasoli, and Ezzat Dadkhah. "Rapid DNA

extraction protocol from stool, suitable for molecular genetic diagnosis of colon cancer."

Iranian Biomedical Journal 11, no. 3 (2007): 203-208.

Abbaszadegan MR, Masood Ziaee, Farhad Khadivi-zand, Zahra Badiee, Bahram Khazaei,

Zohreh Vahedian, Fahimeh Mehrabian and Ezzat Dadkhah. “Carrier detection of hemophilia

in Tyme A southern Khorasan using the 3 polymorphic sites of BclI, HindIII, and AlwNI.”

Blood 3, no. 4, (2007): 291-298.

Kamalidehghan B., Houshmand M., Panahi MS., Abbaszadegan MR, Ismail P., Shiroudi

MB.: TheY8.9 kb Deletion in Tumoral Cell mtDNA Is More Common than Other Deletions

in Gastric Cancer. Archives Med Res 37(7), 848-53 (2006).

Leyla Mostaan, Sefat, Abbaszadegan MR, Kamran Ghafarzadegan, Mohammad Seyedi,

Azadeh Aarabi, Maryam Salehi, and Monavar Afzal Aghaie. "Paper: Evaluationof E-

cadherin and its correlation with lymphatic metastasis and tumor grade in laryngeal SCC.” Ir

J. Otorhinolaryngology 18, no 44, (2006): 61-66

Mahdi Kahrom, Abbaszadegan MR, Hadi Kahrom, and Rahim Vakili. "Nager's acrofacial

dysostosis with hypertrophic cardiomyopathy." Saudi medical journal 27, no. 10 (2006):

1578-1581.

Abbaszadegan MR, Hamid Reza Raziee, Kamran Ghafarzadegan, Mohammad Taghi

Shakeri, Sima Afsharnezhad, and Mohammad Reza Ghavamnasiry. "Aberrant p16

methylation, a possible epigenetic risk factor in familial esophageal squamous cell

carcinoma." International journal of gastrointestinal cancer 36, no. 1 (2005): 47-53.

Rahim Vakili, Alireza Baradaran-Heravi, Babak Barid-Fatehi, Mehran Gholamin, Nosrat

Ghaemi, Abbaszadegan MR. "Molecular analysis of the CYP21 gene and prenatal

diagnosis in families with 21-hydroxylase deficiency in northeastern Iran." Hormone

research 63, no. 3 (2004): 119-124.

Houshang Rafatpanah, Vera Pravica, Reza Farid Hosseini, Abbaszadegan MR, Abbas

Tabatabaei, Abbas Goharjoo, Mohammed Mehdi Etemadi, and Ian V. Hutchinson.

"Association of a novel single nucleotide polymorphism in the human perforin gene with the

outcome of HTLV-I infection in patients from northeast Iran (Mash-had)." Human

immunology 65, no. 8 (2004): 839-846.

Ghaffarzadegan K, Zali MR, Jami Al-Ahmadi K, Hamid Asadzadeh, Abbaszadegan MR.

"Correlation of nuclear P53 Immunoreaction with the histopathologic features in gastric

carcinoma." Archives of Iranian Medicine 7, no. 4 (2004): 279-283.

Abbaszadegan MR, Hamid Reza Raziee, Kamran Ghafarzadegan, and Mohammad Reza

Ghavamnasiry. "p16/INK4a promoter hypermethylation in serum, blood and tumor of

patients with esophageal squamous cell carcinoma." IJBMS 6, no. 4 (2004): 4-9.

M.R. Abbaszadegan Page 22 of 26

Abbaszadegan MR, Omidi A, Niyazi A, Zoheidi MR, Gholamin M, Jami-Ahmadi K,

Ghaffarzadegan K: Prevalence of Human Papilloma Virus type 16 and 18 and expression of

mutant p53 in Esophageal Squamous Cell Carcinoma. Ir J. Basic Med Sci 4(6), 38-42 (2004)

Abbaszadegan MR, Mehran Gholamin, Abbas Tabatabaee, Reza Farid, Massoud Houshmand,

and Morteza Abbaszadegan. "Prevalence of human T-lymphotropic virus type 1 among blood

donors from Mashhad, Iran." Journal of clinical microbiology 41, no. 6 (2003): 2593-2595.

Abbaszadegn MR, Nazanin Pazouki and Mojtaba Sankian. “DNA extraction from Mutation

Detection Enhancement (MDE) gel stained with silver nitrate.” Protocol Online, (2003).

Hamid Yazdani, Daniel C. Chung, Do, Abbaszadegan MR, Kholoud Al-Khayer, Wai-Man

Chan, Milad Yazdani, Kazem Ghodsi, Elizabeth Engele and Elias Traboulsi E. “ A novel

PHOX2A/ARIX mutation in an Iranian family with Congenital Fibrosis of Extraocular

Muscles type 2-CFEOM2.” The American J Ophthalmology 5, no. 136, (2003): 861865

Farah Ashrafzade, Abbaszadegan MR, Nosrat Ghaemi. “Fragile X Syndrome a case report

with fingers anomaly.” Hamedan University Med. Science J 16, no. 2, (2003): 132-134.

Gelmann, David J. Steadman, Jing Ma, Natalie Ahronovitz, H. James Voeller, Sheridan

Swope, Abbaszadegan MR, Kevin M. Brown, Kate Strand, Richard B. Hayes, and Meir J.

Stampfer. “Occurrence of NKX3.1 C154T polymorphism M. R. in men with and without

prostate cancer and studies of its effect on protein function.” Cancer Res 62, no.9, (2002):

2654-9.

Farhad Farid-Hosseini, Pishnamaz Razieh, Reza Farid-Hosseini, Abbaszadegan MR,

Mahmoud Mahmoodi and Maryam Rasteen. “Expression of Interleukin-2R chain (CD25) on

peripheral blood lymphocytes in HTLV-I associated myelopathy/Tropical Spastic Paraparesis

patients.” Arch Ir Med 4, no. 4, (2001): 183-187.

Abbaszadegan MR, Shirdel A., Jamshid Soroori, Behjat Gholami and Mehran Gholamin.

“Detection of minimal residual disease in CML patients after bone marrow transplantation

using a semi-quantitative RT-PCR of BCR-ABL fusion gene (Persian).” Ir J. Basic Med

Sciences 4, no 4, (2001):183-187.

Eva Spitzer, Abbaszadegan MR, Frank Schmidt, Andrea Hauser, Ute Buwitt, Frank‐Roman

Lauter, Kathrin Pötschick, Jutta Krocker, Dirk Elling, and Richard Grosse. "Detection of

BRCA1 and BRCA2 mutations in breast cancer families by a comprehensive two‐stage

screening procedure." International journal of cancer 85, no. 4 (2000): 474-481.

Caryn Lerman, Chanita Hughes, Bruce J. Trock, Ronald E. Myers, David Main, Aba Bonney,

Abbaszadegan MR et al. "Genetic testing in families with hereditary nonpolyposis colon

cancer." JAMA 281, no. 17 (1999): 1618-1622.

Abbaszadegan MR, Abdolreza Varasteh, Mohammad Ali Khoshroo, Behjat Gholami, and

Mehran Gholamin. “Isolation and purification of TAX protein of HTLV-1 virus using

recombinant DNA Techniques.” I.R. Ir Biotechnology 3, (1999): 456-461.

M.R. Abbaszadegan Page 23 of 26

Abbaszadegan MR, Streuwing J., Brown KM., Snider J., Gore-Langton R., Hughes MR.:

Automated detection of highly prevalent mutations in BRCA 1 and 2 genes using a

fluorogenic PCR. Genetic Testing 1, (1998): 171-180.

Abbaszadegan MR, Cress AE., Futscher BW., Bellamy WT., Dalton WS.: Evidence for

cytoplasmic P-glycoprotein location associated with increased multidrug resistance and

resistance to chemosensitizers. Cancer Res 56, (1996): 5435-5442.

Abbaszadegan MR, Anne E. Cress, Bernard W. Futscher, William T. Bellamy, and William

S. Dalton. "Evidence for cytoplasmic P-glycoprotein location associated with increased

multidrug resistance and resistance to chemosensitizers." Cancer research 56, no. 23 (1996):

5435-5442.

Abbaszadegan MR, Bernard W. Futscher, Walter T. Klimecki, Alan List, and William S.

Dalton. "Analysis of multidrug resistance-associated protein (MRP) messenger RNA in

normal and malignant hematopoietic cells." Cancer Research 54, no. 17 (1994): 4676-4679.

Futscher Bernard W, Abbaszadegan MR, Frederick Domann, and William S. Dalton.

"Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells."

Biochemical pharmacology 47, no. 9 (1994): 1601-1606.

Abril ER, Scuderi P, Abbaszadegan MR, Watzl B, Earnest DL.”Vitamin A indirectly

activates kupffer cells by stimulating cytokine production by peripheral blood mononuclear

leukocytes.” Cells Hep Sinusoid 3, (1991): 27-29.

Watzl B., Abril ER., Abbaszadegan MR, Scuderi P., Watson RR.” Effects of ethanol in vivo

on TNF secretion by cultured rat kupffer cells.” Cells Hep Sinusoid 3, (1991): 480-482.

CONFERENCE PROCEEDINGS, ABSTRACTS AND PRESENTATIONS

National and International Conference Proceedings; Selected few:

1. Meysam Moghbeli, Ebrahim Golmakani, Hooman Mosannen Mozaffari, Bahram Memar,

Mohammad Mahdi Forghanifard, Mehran Gholamin, Abbaszadegan MR. Role of NOTCH

Pathway in Targeted Therapy against the Esophageal Cancer Stem Cells. International

Nastaran Cancer Symposium-2016.

2. Amir Abbas Hamidi, Abbaszadegan MR, Mehran Gholamin, Bahram Memar, Ali Jangjoo.

Correlation Analysis Between H.Pylori And Expression Changes Of MAML1 And TWIST1

In Gastric Cancer Patients. International Nastaran Cancer Symposium-2016.

3. Ensiye Khorshidi, Reihaneh Alsadat Mahmoudian, Kazem Anvary, Abbaszadegan MR,

Mehran Gholamin. Assessment Of Changes In Isoforms Of MDM2 Gene, Before And After

The Effect Of 5-Fluorouracil In Esophageal Cancer Cell Lines MKYSE-30). International

Nastaran Cancer Symposium-2016.

M.R. Abbaszadegan Page 24 of 26

4. Mahya Shariat Razavi, Mohammad Mahdi Forghanifard, Dor Mohammad Kordi

Tamandani, Abbaszadegan MR. Key Factors In EMT: Critical Process In Breast Cancer

Malignancy. International Nastaran Cancer Symposium-2016.

5. Niloofar Vashahri Ghamsari, Reihaneh Alsadat Mahmoudian, Mohammad Mahdi

Forghanifard, Abbaszadegan MR, Samaneh Boroumand Noghabi, Shirin Taraz-Jamshidi,

Mehran Gholamin. Analysis of SNP Rs2252070 Of MMP13 Gene In Human Esophageal

Squamous Cell Carcinoma In Iranian Population. International Nastaran Cancer

Symposium-2016.

6. Mohammad eosein Izadpanah, Abbaszadegan MR, Mohammad Mahdi Forghanifard.

Impact Of TWIST1 On OCT-4 Gene Expression In Esophageal Carcinoma Cell Line

(KYSE-30). International Nastaran Cancer Symposium-2016.

7. Taghehchian N, Mashkani B, Yaghmaei P, Abbaszadegan MR. Evaluation Of Biological

Activity And Specificity Of Mesenchymal Epithelial Transition (MET) Proto-Oncogene In

KYSE-30 Cell Line. International Nastaran Cancer Symposium-2016.

8. Fahim Y, Abbaszadegan MR, Forghanifard MM. Clinical Significance Of TEAD4

Expression In Human Esophageal Squamous Cell Carcinoma. International Nastaran Cancer

Symposium-2016.

9. Mohammad Mahdi Forghanifard, Mohammad Hossein Izadpanah, Abbaszadegan MR.

Crosstalk Between EMT And Stemness State In Esophageal Squamous Cell Carcinoma.

International Nastaran Cancer Symposium-2016.

10. Reihaneh Alsadat Mahmoudian, Abbaszadegan MR, Mohammad Mahdi Forghanifard,

Meysam Moghbeli, Faezeh Moghbeli, Mehran Gholamin. Biological And

Clinicopathological Significance Of Cripto-1 Expression In The Progression Of Human

ESCC. International Nastaran Cancer Symposium-2016.

11. Fatemeh Mollaei, Mohammad Mahdi Forghanifard, Abbaszadegan MR. Molecular

Pathways In Gastric Cancer. International Nastaran Cancer Symposium-2016.

12. Fatemeh Fardi Golyan, Morteza Moghaddassian, Mohamad Mahdi Forghanifard, Samaneh

Talebi, Abbaszadegan MR. Whole-Exome Sequencing Reveals A Novel Damaging

Mutation un Seprase un A Family With Esophageal Squamous Cell Carcinoma.

International Nastaran Cancer Symposium-2016.

13. Azadeh Aarabi, Bahram Memar, Rahman Nooraie, Ezzat Dadkhah, Abbaszadegan MR.

Role of INPP5A in progression of esophageal squamous cell carcinoma. 1st International

Nastaran Cancer Symposium-2015

14. Negin Taghehchian, Mohammad Mahdi Forghanifard, Nooriehsharifi Sistani,

Abbaszadegan MR. Immunohistochemical Analysis of Transcription Factors TWIST1

Protein Expression in Esophageal Squamous Cell Carcinoma Patient. 1st International

Nastaran Cancer Symposium-2015

M.R. Abbaszadegan Page 25 of 26

15. Fatemeh Fardi Golyan, Mohamad Mehdi Forghanifar, Abbaszadegan MR. Identification of

Survivin Polymorphism in familial esophageal cancer based on Whole-Exome sequencing

data. 1st International Nastaran Cancer Symposium-2015

16. Abbaszadegan MR. Role of cancer susceptibility genes from DNA repair pathway in

familial Esophageal Squamous Cell Carcinoma. Cancer Susceptibility and Cancer

Susceptibility syndromes. 2014

17. Abbaszadegan MR. Cancer Stem Cells. Medical Genetic Congress. Tehran, Iran, 2013

18. Abbaszadegan MR. Probable genetic factors in Esophageal and gastric cancer

epidemiology. International Multidisciplinary Cancer Congress.

19. Abbaszadegan MR. Cancer stem cells. Medical Genetic Congeress. Tehran, Iran, 2012

20. Abbaszadegan MR. Novel gene search in esophageal squamous cell carcinoma. The Third

International Scientific and Practical Conference- postgenome 2012. Kazan, Russia, 2012.

21. Raeisossadat R, Forghanifard M.M, Sardari S, Tavassoli A, Moghbeli M, Abbaszadegan

MR. Developmental pluripotency associated- 2 (DPPA2) gene may be a metastatic marker

for colorectal cancer. European Human Genetics Conference 2012. Nurnberg, Germany,

2012.

22. Moghbeli M, Forghanifard M.M, Raeisossadat R, Broumand S, Abbaszadegan MR. HIWI

as a prognostic marker for early stages of colorectal cancer. European Human Genetics

Conference 2012. Nurnberg, Germany, 2012.

23. Forghanifard MM, Raeisossadat R, Moghbeli M, Tavassoli A, Montazar M, Gholamin M,

Abbaszadegan MR. Elucidation of SALL4 oncogenic role in colorectal cancer; the first

report. European Human Genetics Conference 2012. Nurnberg, Germany, 2012.

24. Dadkhah E, Moghaddasian M, Arab H, Bustani Farkoush H, Kazemi Noughabi M,

Abbaszadegan MR. Novel mutation in cathepsin C gene(CTSC) and modeling of mutated

protein in three Iranian families with Papillon Lefever Syndrome. European Human

Genetics Conference 2012.Nurnberg, Germany, 2012.

25. Abbaszadegan MR, Forghanifard MM. Impact of cancer testis antigens crosstalk with self

renewal cell signaling pathways in esophageal squamous cell carcinoma. European Human

Genetics Conference 2012.Nurnberg, Germany. June 23-26-2012. (Poster presentation).

26. Abbaszadegan MR, Saidi R, Moaven M, A'rabi A, Homaie-Shandiz F. Novel germ line

BRCA2 mutations in familial esophageal squamous cell carcinoma.12th Iranian Congress of

biochemistry & 4th International Congress of Biochemistry and Molecular Biology,

Mashhad, Iran, 2011.

27. Abbaszadegan MR, Ahadian M, Keify F. Molecular genetics of autosomal recessive

polycystic kidney disease. The 2nd International congress of Iranian Society of Pediatric

Nephrology, Mashhad, Iran, 2011.

M.R. Abbaszadegan Page 26 of 26

28. Arabi A, Meysam Moghbeli M, Maleknejad M, Abbaszadegan MR. Mutational Analysis of

Uroporphyrinogen III Synthase Gene in Iranian Families with Congenital Erythropoietic

Porphyria. Medical Genetic Congress 2011. Tehran, Iran, 2011.

29. Abbaszadegan MR, Saidi R, Moaven O, A'rabi, Homaei- Shandiz F, Gholamin M,

Noferesti GH. Sequential Familial Esophageal Squamous Cell Carcinoma and Breast cancer

in several Pedigrees with BRCA2 Mutations. Medical Genetic Congress 2011. Tehran, Iran,

2011.

30. Abbaszadegan MR, Saidi R, Moaven O, A'rabi A, Homaei- Shandiz F, Noferesti GH.

Familial Esophageal Squamous Cell Carcinoma and Breast cancer in several Pedigrees with

BRCA2 Mutations. European Human Genetics Conference 2011. Amsterdam RAI, the

Netherlands, 2011.

31. Forghanifard MM, Gholamin M, Abbaszadegan MR. In silico and ex vivo analysis of two

chimeric polytope constructs for applications in dendritic cell-based cancer immuno-

genetherapy. European Human Genetics Conference 2011. Amsterdam RAI, the

Netherlands, 2011.

32. Dadkhah E, Naseh H, Farshchian M, Memar B, Sankian M, Bagheri R, Forghanifard MM,

Abbaszadegan MR. New Biomarkers Detected for Esophageal Squamous Cell Carcinoma

using Chemiluminescent cDNA Microarray Gene Expression Profiling. European Human

Genetics Conference 2011. Amsterdam RAI, the Netherlands, 2011.

33. Moghbeli M, A'rabi A, Maleknejad M, Abbaszadegan MR. Mutational Analysis of

Uroporphyrinogen III Synthase Gene in Iranian Families with Congenital Erythropoietic

Porphyria. European Human Genetics Conference. Amsterdam RAI, the Netherlands, 2011.

34. Birjandinejad A, Abbaszadegan MR, Bagheri F, Taraz Jamshidi M, Mousavian A. Familial

osteoarthritis hip by acetabular dysplasia.1st International Congress on Hip Dysplasia, from

newborn to elderly, Mashhad, Iran, 2011.

35. Abbaszadegan MR. State-of-the-art cell-based cancer gene therapies: dendritic cell

vaccines. Iranian Congress on Biology and Applications of Stem Cells. Mashhad, Iran,

2011.

36. Abbaszadegan MR, Gholamin M, Forghanifard MM, Moaven O, Farshchian M, Memar B,

Forghani MN, Dendritic cell-based vaccine in cancer: Total RNA Vs Cancer Testis

Chimeric Antigens RNA in Esophageal Squamous Cell Carcinoma.1st annual scientific

meeting of middle- eastern association for cancer research. Tanta- Egypt, 27-29 Dec 2011.

37. Abbaszadegan MR. Ahadian M, keify F.Molecular genetics of autosomal recessive of

polycystic kidney disease.The 2th international congress of Iranian society of pediatric

nephrology. Mashhad, Iran, 2011.

38. Gholamin M, Moaven O, Farshchian M, Mahmoudi M, Sankian M, Memar B, Rajabi-

Mashhadi MT, Forghani MN, Malekzadeh R, Rajabi-Mashhadi MT, Abbaszadegan MR.

M.R. Abbaszadegan Page 27 of 26

Application of RNA molecule in cancer immunotherapy. Cancer Symposium. Mashhad,

Iran, 2010.

39. Abbaszadegan MR. Hereditary cancers. Cancer Symposium. Mashhad, Iran, 2010.

40. Dadkhah E, Farshchian M, Sankian M, Memar B, Naseh H, Forghani M, Kazemi M,

Abbaszadegan MR. Biomarker detection for Esophageal Squamous Cell Carcinoma using

chemiluminescent cDNA Microarray. Cancer Symposium. Mashhad, Iran, 2010.

41. Forghanifard MM, Farshchian M, Gholamin M, Forghani M, Raeisossadati R, Memar B,

Moaven O, Dadkhah E, Moghbeli M, Abbaszadegan MR. Impact of cancer/testis antigens

crosstalk with the major cell signaling pathways on esophageal squamous cell carcinoma.

Cancer Symposium. Mashhad, Iran, 2010.

42. Ghahraman M, Gholamin M, Me'mar B, Forghani MN, Abbaszadegan MR. Establishment

and Characterization of Esophageal Squamous Cell Carcinoma (ESCC) Cell Line from a

high-incidence area in Iran. Cancer Symposium. Mashhad, Iran, 2010.

43. Farshchian M, Yaghoubi V, Forghanifard MM, Naseh H, Raeisossadati R, Dadkhah E,

Forghani MN, Moghbeli M, Abbaszadegan MR. Gene expression analysis by Real-Time

PCR and PCR-Array technology shed light on pobable new roles of pygo2 in carcinogenesis

pathway of esophageal squamous cell carcinoma. Epigenetics and stem cell conference.

Copenhagen, Denmark, 2010.

44. Farshchian M, Yaghoubi V, Forghanifard MM, Naseh H, Raeisossadati R, Dadkhah E,

Forghani MN, Moghbeli M, Abbaszadegan MR. PYGO-2: A downstraem WNT signaling

component overexpression in esophageal squamous cell carcinoma. 11th Iranian Genetics

Congress, Tehran, Iran, 2010.

45. A'rabi A, Hassani S, Vakili R, Saberi MR, Baradaran-Heravi A, Hashemipour M, Razzaghi-

Azar M, Ahadian M, Keify F, Abbaszadegan MR. Prenatal Diagnosis in Families with 11-

Beta Hydroxylase Deficiency Leads Novel Mutations in Two Patients and their Parents.

11th Iranian Genetics Congress, Tehran, Iran, 2010.

46. Ghahraman M, Abbaszadegan MR, Ghaemi N, Noroozi S, Faraji B, Vakili R. A novel

mutation in the SLC19A2 gene in Iranian families with thiamine responsive megaloblastic

anemia, diabetes and deafness syndrome. 11th Iranian Genetics Congress, Tehran, Iran,

2010.

M.R. Abbaszadegan Page 28 of 26

47. Alizade Nakhayi M, Dadkhah E, Abbaszadegan MR. Heterozygosity analysis of four STR

loci from US Combined DNA Index System in a population of Khorasan province. 11th

Iranian Genetics Congress, Tehran, Iran, 2010.

48. Chavoshi S, Dadkhah E, Tavallaie M, Farshchian M, Raeissossadati R, Velayati A, Toliat

kashani M, Ganji A, Jangjoo A, Abbaszadegan MR. Quantitative analysis of Guanylyl

Cyclase c as a tumor marker, validates this marker for early detection of circulating tumor

cells in the peripheral blood of colorectal cancer patients. 11th Iranian Genetics Congress,

Tehran, Iran, 2010.

49. Raeissossadati R, Velayati A, Dadkhah E, Farshchian M, Chavoshi S, Tavassoli A, Mehrabi

Bahar M, Rajabi Mashhadi MT, Abbaszadegan MR. Absolute quantification of tumor

endothelial marker 8 in the peripheral blood of colorectal cancer patients with real-time RT-

PCR. 11th Iranian Genetics Congress, Tehran, Iran, 2010.

50. Forghanifard MM, Farshchian M, Gholamin M, Naseh H, Memar B, Rajabi Mashhadi MT,

Abbaszadegan MR. Comparative analysis of Cancer/testis antigens expression profile in

esophageal squamous cell carcinoma patients using 5’-nuclease assay in real-time PCR. 11th

Iranian Genetics Congress, Tehran, Iran, 2010.

51. Dadkhah E, Memar B, Naseh H, Sankian H, Farshchian M, Bagheri R, Ahmadi S, Moaven

O, Abbaszadegan MR: Microarray Gene Expression Profiling in Esophageal Squamous

Cell Carcinoma, the First Report from Iran. 11th Iranian Genetics Congress, Tehran, Iran, ,

2010 .

52. Abbaszadegan MR, Hassani S, Vakili R, Saberi MR, Baradaran-Heravi AR, A'rabi A,

Hashemipour M, Razzaghi_Azar M, Baratian A: Novel Mutations in CYP11B1 Gene and its

protein modeling in a Patient with 11β-Hydroxylase Deficiency in Iran. 59th Annual Meeting

of American Society of Human Genetics, Hawaii, 2009.

53. Abbaszadegan MR, Moaven O, Sima HR, Ghaffarzadegan K, Forghani MN, A'rabi A,

Raziee HR: A useful serum marker for early detection of gastric cancer, Aberrant p16

methylation. An AACR special conference in cancer research: Candidate pathways, whole

genome scans: Reconciling results, looking into the future, Carefree, Arizona, USA, 2008.

54. Abbaszadegan MR, Hassani S, Baradaran-heravi A, Vakili R, Arabi A, Razzaghi-azar M.

Novel mutation in CYP11B1 gene in a patient with 11- βhydroxylase deficiency in Iran. The

First International Congress on Health Genomics and Biotechnology, Tehran, Iran, 2007.

55. Abbaszadegan MR, Rastin F, Dadkhah E, Lotfalizadeh M. Microsatellite instability in

young Iranian women with endometrioid type endometrial cancer. The First International

Congress on Health Genomics and Biotechnology, Tehran, Iran, 2007.

56. Abbaszadegan MR, Baradaran Heravi A, Vakili R, Gholamin M, Ghaemi N: Three novel

CYP21A2 mutations and their protein modeling in patients with classical 21-hydroxylase

M.R. Abbaszadegan Page 29 of 26

deficiency from northeastern Iran. 3rd Annual Metabolic Diseases World Summit, San

Diego, CA, USA, 2007.

57. Abbaszadegan MR, Raziee HR, Afsharnejad S, Ghaffarzadegan K, Ghavamnasiri MR.

Aberrant p16 Methylation, a possible predisposing factor in familial esophageal squamous

cell carcinoma. 95th Annual meeting of American Association for Cancer Research,

Orlando, Fl, 2004.

58. Abbaszadegan MR, Heidari N, Pazuki N, Jami-Ahamadi K: Mitochondria DNA Alteration

in Gastric Cancer. The First Scientific Meeting of Asian Society for Meitochondrial

Research and Medicine. Seoul, Korea, February 2003.

Invited Presentations and Workshops; Selected few:

Abbaszadegan MR, Tavasoli A, Velayati A, Sima HR, Vosooghinia H, Farzadnia M,

Asadzedeh H, Gholamin M, Dadkhah E, Aarabi A. Stool-based DNA testing, a new

noninvasive method for colorectal cancer screening, the first report from Iran. The King

Hussein Cancer & Biotechnology Institute, The National Cancer Institute of the US, and

Duke University, Middle East and North Africa Cancer Research Conference, Amman,

Jordan, 3 – 4 Sept, 2007.

Abbaszadegan MR. Molecular Genetics & Epigenetic in upper G.I. Cancers. Advance

Molecular Genetics Course, Tehran, Iran, June 10-12, 2006.

Abbaszadegan MR. Molecular genetics and epigenetics in upper GI cancers. The first

Esophageal Cardia Cancer Summit, Scientific sponsors: ISMO, DDRC, IAGH, Iran &

IARC, France, Tehran, Iran, Dec. 13-14, 2005.

Abbaszadegan MR, Scientific Chair, Workshop: Bioinformatics, Webinar to MUMS, 2010.

Abbaszadegan MR, Scientific Chair, Workshop: Diagnostic techniques in Human

Genetics, MUMS, 2009.

Abbaszadegan MR, Scientific Chair, Workshop: Cloning in Eukaryotic Cells, MUMS,

2009.

STUDENTS AND POST DOCS ADVISED

M.Sc. Awarded:

Morshedi-Rad D. (in progress), Zargari F. (in progress), Mollaie F. 2017, Taghehchian N.

2016, Forouzanfar N. 2015, Fardi E. 2015, Khalilipour N. 2016, Hamidi A.2016, Sharifi S.

2015, Tafazzoli A 2014, Nasiri Aghdam M. 2014, Azaraz Sh. 2014, Mahmoudian R. 2013,

Ardalan S. 2013, Pirhoushyaran M. 2012, Taleb S. 2012, Moradi F. 2012, Raad A. 2012,

Torkamandi S. 2012, Raeissosadat R. 2010, Chavoshi S. 2010, Maleki M. 2010, Dadkhah E.

2009, Moghbeli M. 2009, Nakhaee M. 2009, Abrishami T. 2009, Razavipour E. 2009,

Sardari S. 2008, Emami Vahid E. 2006, Khatami F. 2006, Jafarzadeh N. 2006, Afsharnezhad

S. 2005, Pazuki N. 2004, Tohidi F. 2003, Khoshru M. 2002, Gholamin M. 2001,

M.R. Abbaszadegan Page 30 of 26

Ph.D. Awarded:

Reyhaneh Mahmoudian (in progress), Sima Ardalan (in progress), Mahya shariat Razavi (in

progress), Fatemeh Rafinia (in progress), Keyvani V (in progress), Vahid Bagheri 2017,

Meysam Moghbeli 2016, Mohammad Mahdi ForghaniFard 2011, Mehran Gholamin 2008

M.D. Final Thesis:

Oliazadeh P. (in progress), Zeinalzadeh M 2015, Sorouri A 2014, Soltani Delgosha M 2012,

Saeedi R 2012, Nooraee R 2012, Naghibzadeh B 2011, Moaven O 2007, Hassani S 2007,

Baradaran-Heravi AR 2004, Fatehi B 2004, Khameneh-Bagheri A 2001, Farid-hosseini F

2001, Sorouri-Kharashad J 2000.

Residency Final Thesis:

Mousavi L. (OB/Gyn Resident, in progress), Barabadian S. 2014, Abadian MB (Resident

Dermatology) 2009, Dehghan Menshadi H (Resident Pediatric) 2013, Shirkani A (Fellow-

allergy and clinical Immunology) 2013,Broumand S(Resident- Pthology) 2013, Daliri M

(Resident Surgery) 2013, Zand Karimi MR (Fellow- allergy and clinical Immunology) 2012,

Boostani HR (Resident-Periodental) 2011, Manzari F (Resident-Pathology) 2010, Naseh H.

(Resident-Pathology) 2010, Abadian M. (Resident-Dermatology) 2008, Badiei R. (Resident-

Syrgery) 2007, Rastin F. (Resident-OBGyn) 2007, Sarafraz F. (Fellow-OBGyn) 2006,

Post-Docs:

Mazloum Khorasani Z. (Endocrinology- in progress), Velayati A. (fellow-Neurology) 2009,

Razaei Babak A. (Resident-dentistry) 2005, Raziei HR (Resident- Oncology) 2005,

Niazi A. (Resident – Pathology) 2003, Zahidi MR. (Resident – Pathology) 2003,

Talasaz Firoozi E. (Pharm D-final thesis) 2000.