CURRICULUM VITAE Gregory Scott...

38
Page 1 of 38 CURRICULUM VITAE Gregory Scott Schultz Business Address Department of Obstetrics & Gynecology Institute for Wound Research 1600 SW Archer Road University of Florida Gainesville, Florida 326l0-0294 Phone: (352)-273-7560 FAX: (352)-392-6994 E-Mail: [email protected] Education 1967-71 B.S. Honors Program in Biochemistry Oklahoma State University, Stillwater, Oklahoma 1971-76 Ph.D. Biochemistry Oklahoma State University, Stillwater, Oklahoma Advisor: Dr. Kurt Ebner, Regents Professor 1976-79 Postdoctoral Cell Biology Yale University, New Haven, Connecticut Fellow Advisor: Dr. James D. Jamieson, Professor & Chair Academic Appointments 2014-2015 Dunlevie Honors College Professorship, University of Florida 2010- 2012 UF Research Foundation Professor, University of Florida 1989-2010 Professor of Obstetrics/Gynecology, University of Florida, College of Medicine 1985-1989 Associate Professor of Ophthalmology, University of Louisville School of Medicine 1985-1989 Associate Professor of Biochemistry, University of Louisville School of Medicine 1979-1985 Assistant Professor of Biochemistry, University of Louisville School of Medicine 1976-1979 Postdoctoral Research Associate with Dr. James D. Jamieson, Professor of Cell Biology, Yale University School of Medicine 1974-1976 Graduate student with Dr. Kurt Ebner, Professor and Chairman Department of Biochemistry, Kansas University Medical Center, Kansas City, Kansas 1971-1974 Graduate student with Dr. Kurt Ebner, Regents Professor of Biochemistry Oklahoma State University, Stillwater, Oklahoma Professional Societies American Society for Biochemistry and Molecular Biology The Wound Healing Society Association for Research in Vision and Ophthalmology Awards and Honors Phi Kappa Phi, 1971 Medicinae Doctorem (honoris causa) awarded by University of Linköping, Sweden, 1996 Everett Kinsey Lecturer of the Contact Lens Association of Ophthalmologist, 1997 1st Ethicon Endo-Surgery Plenary Lectureship of the American Society for Reproductive Medicine, 1997 Research Bank Award, University of Florida, 1997 Professorial Excellence Program Award, University of Florida, 1998 President of the Wound Healing Society, 1999-2001 Sustained Excellence Professors Award, University of Florida, 2001, 2008 Thygeson Lecturer of the Ocular Microbiology and Immunology Group, 2002 TIME Magazine Innovation Leader, March 20, 2006 Basic Science Research Award, University of Florida College of Medicine, 2008 Honored Keynote Lecturer, Japanese Society of Pressure Ulcers, 2008 International Educator of the Year, College of Medicine, University of Florida, 2008 Exemplary Teacher, College of Medicine, University of Florida, 2009 Silver Fellow of the Association for Research in Vision and Ophthalmology, 2010 University of Florida Research Foundation Professorship Award, 2010-2012

Transcript of CURRICULUM VITAE Gregory Scott...

Page 1 of 38

CURRICULUM VITAE

Gregory Scott Schultz

Business Address

Department of Obstetrics & Gynecology Institute for Wound Research 1600 SW Archer Road University of Florida Gainesville, Florida 326l0-0294 Phone: (352)-273-7560 FAX: (352)-392-6994 E-Mail: [email protected]

Education 1967-71 B.S. Honors Program in Biochemistry Oklahoma State University, Stillwater, Oklahoma 1971-76 Ph.D. Biochemistry Oklahoma State University, Stillwater, Oklahoma Advisor: Dr. Kurt Ebner, Regents Professor 1976-79 Postdoctoral Cell Biology Yale University, New Haven, Connecticut Fellow Advisor: Dr. James D. Jamieson, Professor & Chair

Academic Appointments 2014-2015 Dunlevie Honors College Professorship, University of Florida 2010- 2012 UF Research Foundation Professor, University of Florida 1989-2010 Professor of Obstetrics/Gynecology, University of Florida, College of Medicine 1985-1989 Associate Professor of Ophthalmology, University of Louisville School of Medicine 1985-1989 Associate Professor of Biochemistry, University of Louisville School of Medicine 1979-1985 Assistant Professor of Biochemistry, University of Louisville School of Medicine 1976-1979 Postdoctoral Research Associate with Dr. James D. Jamieson, Professor of Cell Biology, Yale University School of Medicine 1974-1976 Graduate student with Dr. Kurt Ebner, Professor and Chairman Department of Biochemistry, Kansas University Medical Center, Kansas City, Kansas 1971-1974 Graduate student with Dr. Kurt Ebner, Regents Professor of Biochemistry Oklahoma State University, Stillwater, Oklahoma

Professional Societies American Society for Biochemistry and Molecular Biology The Wound Healing Society Association for Research in Vision and Ophthalmology

Awards and Honors Phi Kappa Phi, 1971 Medicinae Doctorem (honoris causa) awarded by University of Linköping, Sweden, 1996 Everett Kinsey Lecturer of the Contact Lens Association of Ophthalmologist, 1997 1st Ethicon Endo-Surgery Plenary Lectureship of the American Society for Reproductive Medicine, 1997 Research Bank Award, University of Florida, 1997 Professorial Excellence Program Award, University of Florida, 1998 President of the Wound Healing Society, 1999-2001 Sustained Excellence Professors Award, University of Florida, 2001, 2008 Thygeson Lecturer of the Ocular Microbiology and Immunology Group, 2002 TIME Magazine Innovation Leader, March 20, 2006 Basic Science Research Award, University of Florida College of Medicine, 2008 Honored Keynote Lecturer, Japanese Society of Pressure Ulcers, 2008 International Educator of the Year, College of Medicine, University of Florida, 2008 Exemplary Teacher, College of Medicine, University of Florida, 2009 Silver Fellow of the Association for Research in Vision and Ophthalmology, 2010 University of Florida Research Foundation Professorship Award, 2010-2012

Page 2 of 38

Honorary Visiting Professor, University of Cardiff, 2012-2017 Elizabeth Dunlevie Honors College Professorship, University of Florida, 2014-2015 Lifetime Achievement Award, University of Florida, College of Medicine, 2017

Peer Reviewed Scientific Journal Publications Science Citation Index & Elsevier list over 15,021 total citations by 30,819 unique authors in April 2017 to Dr. Schultz’s published research papers, reviews and patents: h-index = 63. 1. W. Frevert, T. Wright, K. Farmer, Q.P. Yang, A. Struk G. Schultz. Evaluation of Biofilms on Explanted Shoulder

Prostheses using Functional Biofilm Assay and Scanning Electron Microscopy, J Surg Orthopaedics Adv, in press, 2017.

2. M. Tenenhaus, G. D. Mulder, G. Schultz. Hyaluronic Acid Dressings for Burn and Acute Wound Treatment: A Comprehensive Literature Review, Burns, in press, 2017.

3. D.J. Gibson, S. Tuli, G.S. Schultz. Dual Phase Iontophoresis for the Delivery of Antisense Oligonucleotides, Nucleic Acid Therapeutics, in press, 2017.

4. S. Jeong, G.S. Schultz, D.J. Gibson. Testing the Influence of Surfactant-Based Wound Dressings on Proteinase Activity, International Wound J, in press, 2017.

5. Z.L. Watson, M.K. Ertel, A.S. Lewin, S.S. Tuli, G.S. Schultz, D.M. Neumann, D.C. Bloom. Adeno-Associated Virus Vectors Efficiently Transduce Mouse and Rabbit Sensory Neurons Co-Infected with HSV-1 Following Peripheral Inoculation, J Virology, in press, 2017.

6. A. Omar, J.B. Wright, G.S. Schultz, R.E. Burrell, and P. Nadworny. Microbial Biofilms and Chronic Wounds, Microorganism, 5(9):1-15, 2017.

7. Q. Yang, C. Larose, A. Della Porta, G. Schultz, D.A. Gibson. Surfactant Based Wound Dressing Can Reduce Bacterial Biofilms in a Porcine Skin Explant Model, International Wound J, 14(2):408-413, 2017.

8. X. Feng, L. Pi, S. Sriram, G.S. Schultz, D. J. Gibson. Connective Tissue Growth Factor Is Not Necessary for Haze Formation in Excimer Laser Wounded Mouse Corneas, PLoSOne, 12(2):e0172304, 2017.

9. L.R. Proietto, R.D. Whitley, D.E. Brooks, G.S. Schultz, D.J. Gibson, W.M. Berkowski Jr, M.E. Salute and C.E. Plummer. Development and Assessment of a Novel Canine Ex Vivo Corneal Model, Current Eye Res, 42(6):813-821, 2017.

10. Y. Abouelhassan, Q. Yang, M.T. Nguyen, M. Rolfe, H. Yousaf, G.S. Schultz, R.W. Huigens. Nitroxoline: A Broad-Spectrum Persister Cell-Killing and Biofilm-Eradicating Agent Against Pathogenic Bacteria, International J Antimicrobial Agents, 49:247–251, 2017.

11. G. Nakagami, G. Schultz, D.J. Gibson, P. Phillips, A. Kitamura, T. Minematsu, T. Miyagaki, A. Hayashi, S. Sasaki, J. Sugama, H. Sanada. Biofilm Detection By Wound Blotting Can Predict Slough Development In Pressure Ulcers: A Prospective Observational Study, Wound Repair Regen, 25(1):131-138, 2017.

12. P.L. Tran, A.N. Hamood, A. de Souza, G. Schultz, B. Liesenfeld, D. Mehta, D. Webster, T.W. Reid. The Ability Of Quaternary Ammonium Groups Attached To A Urethane Bandage, To Inhibit Bacterial Attachment And Biofilm Formation In A Mouse Wound, International Wound J, 14(1):79-84, 2017.

13. K.P. Fennelly, C. Ojano-Dirain, Q.P. Yang, L. Lu, A. Progulske-Fox, G. Wang, P. Antonelli, G. Schultz. Biofilm Formation by Mycobacterium abscessus within a Lung, Am J Resp Crit Care Med, 193(6):692-693, 2016.

14. M. Malone, T. Bjarnsholt, A.J. McBain, G.A. James, P. Stoodley, D. Leaper, M. Tachi, G. Schultz, T. Swanson, R.D. Wolcott. The Prevalence Of Biofilms In Chronic Wounds: A Systematic Review And Meta-Analysis Of Published Data, J Wound Care, 25(12):1-12, 2016.

15. N. Orobello, C Ojano-Dirain, G.S. Schultz, P.A. Antonelli. Ciprofloxacin Decreases Collagen in Mouse Tympanic Membrane Fibroblasts, Otolaryngology Head Neck Surgery, 115(1):127-132, 2016.

16. C. Magin, D. Neale, M. Drinker, B. Willenberg, S. Reddy, K. La Perle, G. Schultz, A. Brennan. Evaluation of a Bilayered, Micropatterned Hydrogel Dressing for Full-Thickness Wound Healing, Exp Biol Med, 241(9):9861-995, 2016.

17. G. Bohn, B. Liden, G.S. Schultz, Q. Yang, D. Gibson. Ovine Collagen Dressing: The Next Generation in Collagen Dressing for Wound Care, Advances in Wound Care, 5:1-10, 2016.

18. S. Ramsay, L. Cowan, J.M. Davidson, L. Nanney, G. Schultz. Wound Samples: moving towards a standardized method of collection and analysis, International Wound J, 13(5):880-891, 2016.

19. L. Pi, P.M. Robinson, M. Jorgensen, S.H. Oh, A.R. Brown, P.H. Weinreb, T.L. Trinh, P. Yianni, C. Liu, A. Leask, S.M. Violette, E.W. Scott, G.S. Schultz, B.E. Petersen. Connective Tissue Growth Factor and Integrin αvβ6: a New Pair of Regulators Critical for Ductular Reaction and Biliary Fibrosis, Hepatology, 61:678-691, 2015.

20. Q. Yang, D.T. Kerekes, G.S. Schultz, D.J. Gibson. Antibacterial and Flow Rate Assessment of a Non-Adherent Layer Interface on a Silver Alginate Dressing, Wounds, 27:1-4, 2015.

21. L. Pi, P-Y. Chung, S. Sriram, M.M. Rahman, W-Y. Song, E.W. Scott, B.E. Petersen, G. S. Schultz. CTGF Differentially Binds to Members of the Cysteine Knot Superfamily and Potentiates PDGF-B Signaling in Rabbit Corneal Fibroblast Cells, World J Biochemistry, 6:379-388, 2015.

22. G.M. Martorana , J.L. Schaefer, M.A. Levine, Z.L. Lukowski, J. Min, C.A. Meyers, G.S. Schultz, M.B. Sherwood. Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function Following Glaucoma Filtration

Page 3 of 38

Surgery in a Rabbit Model, PLoS ONE, 10(9): e0138054, 2015. 23. P.L. Tran, A.N. Hamood, A. de Souza, G. Schultz, B. Liesenfeld, D. Mehta, D. Webster, T.W. Reid. A Study on the

Ability of Quaternary Ammonium Groups Attached to a Polyurethane Foam Wound Dressing to Inhibit Bacterial Attachment and Biofilm Formation, Wound Repair Regen, 23:74-81, 2015.

24. P.L Phillips, Q.P. Yang, S. Davis, E.M. Sampson, J.I. Azeke, A. Hamad, G.S. Schultz. Antimicrobial Dressing Efficacy Against Mature Pseudomonas Aeruginosa Biofilm on Porcine Skin Explants, International Wound J, 12:469-483, 2015.

25. L. Pi, M. Jorgensen, S. Oh, Y. Protopapadakis, A. Gjymishka, A. Brown,.P. Robinson, C. Liu, E.W. Scott, G.S. Schultz, B.E. Petersen. A Disintegrin and Metalloprotease with Thrombospondin Type I Motif 7: A New Protease for Connective Tissue Growth Factor in Hepatic Progenitor/Oval Cell Niche, Am J Pathol, 185:1552-1563, 2015.

26. S. Gowda, D.A. Weinstein, T.D. Blalock, K. Gandhi, B.A. Mast, G. Chin, G.S. Schultz. Topical Application of Recombinant Platelet-Derived Growth Factor Increases the Rate of Healing and the Level of Proteins that Regulate This Response, International Wound J, 12(5): 564-571, 2015.

27. D.J. Gibson, Q. Yang, D.T. Kerekes, G.S. Schultz. Medical Honey and Silver Dressings Do Not Interfere with Each Other’s Key Functional Attributes, Wounds, 26:309-316, 2014.

28. S. Sriram, D. Gibson, P. Robinson, L. Pi, S. Tuli, A.S. Lewin, G. Schultz. Assessment of Anti-Scarring Therapies in Ex Vivo Organ Cultured Rabbit Corneas, Exp Eye Res, 125:173-182, 2014.

29. D.J. Gibson, L. Pi, H. Xia, S. Sriram, C. Mao, B.E. Petersen, E.W. Scott, A. Leask, G.S. Schultz. Conditional Knockout of CTGF Affects Visual Function and Corneal Wound Healing, Invest Ophthalmol Vis Sci, 55:2062-2070, 2014.

30. S. Sriram, P. Robinson, L. Pi, A. Lewin, G. S. Schultz. Triple Combination siRNAs Targeting TGF1, TGFR2 and CTGF Enhances Reduction of Collagen I and Smooth Muscle Actin in Corneal Fibroblasts, Invest Ophthalmol Vis Sci, 54:8214-8223, 2013, PMC3867185.

31. P.L. Phillips, Q. Yang, G.S. Schultz. The Effect of Negative Pressure Wound Therapy with Periodic Instillation Using Antimicrobial Solutions on Pseudomonas Aeruginosa Biofilm on Porcine Skin Explants, International Wound J, 10 (suppl. 1):48-55, 2013.

32. S. Sriram, D. Gibson, P. Robinson, S. Tuli, A. Lewin, G. Schultz. Reduction of Corneal Scarring in Rabbits by

Targeting the TGF1 Pathway With a Triple siRNA Combination, Adv Biosci Biotech, 4:47-55, 2013. http://dx.doi.org/10.4236/abb.2013.410A4005

33. P.M. Robinson, T.D. Chuang, S. Sriram, L. Pi, X. Luo, B.E. Petersen, G.S. Schultz. MicroRNA Signature in Wound

Healing Following Excimer Laser Ablation: Role of miR-133b on TGF1, CTGF, SMA and COL1A1 Expression Levels in Rabbit Corneal Fibroblasts, Invest Ophthalmol Vis Sci, 54:6944-6951, 2013.

34. Q.P. Yang, P. Phillips, E. Sampson, A. Progulske-Fox, P. Antonelli, S. Jin, G. Schultz. Development of a Novel In Vitro Porcine Skin Explant Model For The Assessment Of Mature Bacterial Biofilms, Wound Repair Regen, 21:704-714, 2013.

35. D. J. Gibson, S. Tuli, G.S. Schultz. The Progression of Haze Formation in Rabbit Corneas Following Phototherapeutic Keratectomy, Invest Ophthalmol Vis Sci, 54:4776-4781, 2013. PMCID:PMC3719447

36. L. Cowan, J. Stechmiller, P. Phillips, Q.P. Yang and G. Schultz. Chronic Wounds, Biofilms and Use of Medicinal Larvae, Ulcers, Article ID 487024, 7 pages; http://dx.doi.org/10.1155/2013/487024, 2013.

37. S.S. Radhakrishnan, P.M. Robinson, T.D. Blalock, G. Secker, J. Daniels, G.R. Grotendorst, G.S. Schultz. Effect of Connective Tissue Growth Factor on Protein Kinase Expression and Activity in Human Corneal Fibroblasts, Invest Ophthalmol Vis Sci, 53:8076-8085, 2013. PMC3522434

38. Z.l. Lukowski, J. Min, A.R. Beattie, C.A. Meyers, M.A. Levine, G.S. Schultz, D.A. Samuelson, M.B. Sherwood. Prevention of Ocular Scarring Following Glaucoma Surgery Using the Monoclonal Antibody LT1009 (Sonepcizumab™) in a Rabbit Model, J Glaucoma, 22:145-151, 2013.

39. P.M. Robinson, T.S. Smith, D. Patel, M. Dave, A.S. Lewin, L. Pi, E.W. Scott, S.S. Tuli, G.S. Schultz. Proteolytic Processing of Connective Tissue Growth Factor in Normal Ocular Tissues and During Corneal Wound Healing, Invest Ophthalmol Vis Sci, 53:8093-8103, 2012.

40. D.J. Gibson and G.S. Schultz. Ectopic Epithelial Implants Following Surface Ablation of the Cornea. Invest Ophthalmol Vis Sci, 53:7760-7765, 2012.

41. J. Min, Z.L. Lukowski, M.A. Levine, C.A. Meyers, A.R. Beattie, G.S. Schultz, D.A. Samuelson, and M.B. Sherwood. Comparison Of Single Versus Multiple Injections Of The Protein Saratin For Prolonging Bleb Survival In A Rabbit Model, Invest Ophthalmol Vis Sci, 53:7625-7630, 2012.

42. L. Pi, A. Shenoy, J. Liu, S. Kim, N. Nelson, H. Xia, W.W. Hauswirth, B.E. Petersen, G.S. Schultz, E.W. Scott. CCN2/CTGF Regulates Neovessel Formation via Targeting Structurally Conserved Cystine Knot Motifs in Multiple Angiogenic Regulators, FASEB J, 26:3365-3379, 2012.

43. T.D. Blalock, D.J. Gibson, M.R. Duncan, S.S.Tuli, G.R. Grotendorst, G.S. Schultz. A Connective Tissue Growth Factor Signaling Receptor in Corneal Fibroblasts, Invest Ophthalmol Vis Sci, 53:3378-3394, 2012.

44. J. Min, Z.L. Lukowski, C.A. Meyers, A.R. Beattie, M.A. Levine, G.S. Schultz, D.A. Samuelson, M.B. Sherwood. Prevention Of Ocular Scarring Post Glaucoma Filtration Surgery Using The Inflammatory Cell And Platelet Binding Modulator Saratin In A Rabbit Model. PLoS ONE, 7(4):e35627, 2012.

Page 4 of 38

45. A. Tandon, J.C. Tovey, M.R. Waggonor, A. Sharma, J.W. Cowden, V. Lopez, Y. Liu, D.J. Gibson; G.S. Schultz, R.R. Mohan. Vorinostat: A Potent Agent to Prevent Laser-Induced Haze in the Cornea In Vivo. J Refractive Surgery, 28:285-290, 2012.

46. R.R. Mohan, J.C.K. Tovey, A. Sharma, G.S. Schultz, J.W. Cowden, A. Tandon. Targeted Decorin Gene Therapy Delivered with Adeno-Associated Virus Effectively Retards Corneal Neovascularization In Vivo. PLoS ONE, 6:e26432, 2012.

47. J. M. Benson, J.C. Seagrave, W.M. Weber, C.D. Santistevan, G.R. Grotendorst, G.S. Schultz, T.H. March, Time Course of Lesion Development in the Hairless Guinea Pig Model of Sulfur Mustard Induced Dermal Injury, Wound Repair Regen, 19:348-357, 2011.

48. A. Mikhaylova, B. Liesenfeld, D. Moore, W. Toreki, J. Vella, C. Batich, G. Schultz. Preclinical Evaluation of Antimicrobial Efficacy and Biocompatibility of a Novel Bacterial Barrier Dressing, Wounds, 23:24-31, 2011.

49. R.D. Wolcott, K.P. Rumbargh, G. James, G. Schultz, P. Phillips Q. Yang, C. Watters, P.S. Stewart, S.E. Dowd. Biofilm Maturity Studies Indicate Sharp Debridement Opens a Time-Dependent Therapeutic Window, J Wound Care, 19:320-328, 2010.

50. P-Y. Chung, T-H. Lin, G Schultz, C. Batich, P. Jiang. Nanopyramid Surface Plasmon Resonance Sensors, Applied Physics Letters, 96:261108, 2010.

51. N.C. Mishra, J. Rirsimaah, T. March, W. Weber, J. Benson, R. Jaramillo, J. Seagrave, G. Schultz, G. Grotendorst M. Sopori. Sulfur Mustard Induces Immune Sensitization in Hairless Guinea Pigs, International Immunopharmacol, 10:193-199, 2010.

52. P.J. Antonelli, A.G. Winterstein, G.S. Schultz. Topical Dexamethasone and Tympanic Membrane Perforation Healing in Otitis Media, Otology Neurology, 31:519-523, 2010.

53. J. Liu, M. Saghizadeh, S.S. Tuli, A.A. Kramverov, A.S. Lewin, D.C. Bloom, W.W. Hauswirth, M.G. Castro, G.S. Schultz, A.V. Ljubimov. Different Tropisms of Adenovirus and Adeno-Associated Viruses to Corneal Cells: Implications for Corneal Gene Therapy, Molecular Vision, 14:2087-2096, 2008.

54. B. Baskovich, E.M. Sampson, G.S. Schultz, L.K.S. Parnell. Wound Dressing Components Degrade Proteins Detrimental to Wound Healing, International Wound J, 5:543-551, 2008.

55. B.B. Childress, G.S. Schultz, J.K. Stechmiller. Arginine Metabolites in Wound Fluids from Pressure Ulcers: A Pilot Study, Biol Res Nursing, 10:87-92, 2008.

56. M. Sisco, Z.B. Kryger, K.D. O’Shaughnessy, P.S. Kim, G.S. Schultz, X.Z. Ding, N.K. Roy, N.M. Dean, T.A. Mustoe. Antisense Inhibition of Connective Tissue Growth Factor (CTGF/CCN2) mRNA Limits Hypertrophic Scarring Without Affecting Wound Healing In Vivo, Wound Repair Regen, 16:661-673, 2008.

57. C. Clement, M. Popp, D. Bloom, G. Schultz, L. Liu, D. Neumann, P. Bhattacharjee, J. Hill. Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit trigeminal ganglia, Molecular Vision, 14:1209-1221, 2008.

58. J. Liu, A.S. Lewin, S.S Tuli, S.C. Ghivizzani, G.S. Schultz, D.C. Bloom. Reduction in Severity of a Herpes Simplex Virus Type 1 (HSV-1) Murine Infection by Treatment with a Ribozyme Targeting the UL20 Gene RNA, J Virology, 82:7467-7474, 2008.

59. G.A. Secker, A.J. Shortt, E. Sampson, Q.P. Schwartz, G.S. Schultz, J.T. Daniels. TGF-beta Stimulated Re-Epithelialization is Regulated by CTGF and Ras/MEK/ERK Signaling, Exp Cell Res, 314:131-142, 2008.

60. Z. Jiang, P. Yu, M. Tao, C. Fernandez, C. Ifantides, O. Moloye, G.S. Schultz, C.K. Ozaki, S.A. Berceli. TGF- and CTGF Mediated Fibroblast Recruitment Influences Early Outward Vein Graft Remodeling, Am J Physiol Heart Circ Physiol, 293:H482-H488, 2007.

61. O. Kloeters, S-X. Jia, N. Roy, G.S. Schultz, G. Leinfellener, T.A. Mustoe. Alteration of Smad3 Signaling in Ischemic Rabbit Dermal Ulcer Wounds, Wound Repair Regen, 15:341-349, 2007.

62. M.P. Popp, L. Liu, A. Timmers, D.W. Esson, L. Shiroma, C. Meyers, S. Berceli, M. Tao, G. Wistow, G.S. Schultz, M.B. Sherwood. Development of a Microarray Chip for Gene Expression in Rabbit Ocular Research, Molecular Vision, 13:164-173, 2007.

63. O. Cheng, R. Thuillier, E. Sampson, G. Schultz, P. Ruiz, X. Zhang, P.S.T. Yuen, R.B. Mannon. Connective Tissue Growth Factor (CTGF) is a Biomarker and Mediator of Kidney Allograft Fibrosis, Am J Transplantation, 6:2292-2306, 2006.

64. S.A. Berceli, A. Jiang, N.V. Klingman, G.S. Schultz, C.K. Ozaki. Early Differential MMP-2 and -9 Dynamics During Flow Induced Arterial and Vein Graft Adaptations, J Surg Res, 134:327-334, 2006.

65. M. John-Aryankalayil, N. Dusku, C. Jaworski, C.A. Cox, G. Schultz, J. Smith, K.E. Ramsey, D.A. Stephan, T.W. Reid, D. A. Carper. Microarray and Protein Analysis of Human Pterygia, Molecular Vision, 12:55-64, 2006.

66. P.J. Antonelli, G.S. Schultz, D.J. Sundin, P.A. Pemberton, P.J. Barr. Alpha 1-Antitrypsin Single Dose Adjuvant Therapy for Acute Otitis Media, Otolaryngol Head Neck Surg, 135:111-115, 2006.

67. S.S. Tuli, R. Liu, T.D. Blalock, C. Chen, M.H. Goldstein, G.S. Schultz. Immunohistochemical Localization of TGF-,

TGF-, EGF, and their Receptors in Rat Corneas During Healing of Excimer Laser Ablation, Current Eye Res, 31:709-719, 2006.

68. D. Kilpadi, J.K. Stechmiller, B. Childress, L. Cowan, M. Comerio, K. Kieswetter, G. Schultz. Composition of Wound Fluid from Pressure Ulcers Treated with Vacuum Assisted Closure® Therapy in Home Health or Extended Care

Page 5 of 38

Patients: A Pilot Study, Wounds, 18:119-126, 2006. 69. J.K. Stechmiller, B. Childress, L. Cowan, G. Stevens, D. Kilpadi, G.S. Schultz. Effect of Negative Pressure Wound

Therapy on the Expression of TNF-α, IL-1β, MMP-2, MMP-3 and TIMP-1 in Wound Fluid of Adults with Pressure Ulcers, Wound Repair Regen, 14:371-374, 2006.

70. G.B. van Setten, L. Berglin, T.D. Blalock, G. Grotendorst, G. Schultz. Detection of CTGF in Subretinal Fluid of Retinal Detachment: Possible Contribution to Subretinal Scar Formation, Ophthalmic Res, 37:289-292, 2005.

71. T.T. Thula, G.S. Schultz, C. Batich, R. Tran-Son-Tay. Effects of Epidermal Growth Factor and Basic Fibroblast Growth Factor on Irradiated Rat Parotid Glands, Ann Biomed Eng, 33:685-695, 2005.

72. K.L. Watts, E.M. Sampson, G.S. Schultz, M.A. Spiteri. Simvastatin Inhibits Growth Factor Expression and Modulates Pro-Fibrogenic Markers in Lung Fibroblasts, Am J Respir Cell Mol Biol, 32:290-300, 2005.

73. P.J. Antonelli, G.S. Schultz, J.S. Cantwell, D.J. Sundin, P.A. Pemberton, P.J. Barr. Inflammatory Proteases in Chronic Otitis Externa, Laryngoscope, 115:651-654, 2005.

74. F.J. Ollivier, D.E. Brooks, G.B. van Setten, G.S. Schultz, K.N. Gelatt, G.R. Stevens, T.D. Blalock, S.E. Andrew, A.M. Komaromy, M.E. Lassaline, M.E. Kallberg, T.J. Cutler. Profiles of Matrix Metalloproteinase Activity in Equine Tear Fluid During Corneal Healing in 10 Horses with Ulcerative Keratitis, Vet Ophthalmol, 7:397-405, 2004.

75. D.W. Esson, M.P. Popp, L. Liu, G.S. Schultz, M.B. Sherwood. Microarray Analysis of the Failure of Filtering Blebs in a Rat Model of Glaucoma Filtering Surgery, Invest Ophthalmol Vis Sci, 45: 4450-4462, 2004.

76. S.A. Berceli, Z. Jiang, N.V. Klingman, C.L. Pfahnl, Z.S. Abouhamze, C.D. Frase, G.S. Schultz, C.K. Ozaki. Differential Expression and Activity of MMPs during Flow–Modulated Vein Graft Remodeling, J Vasc Surg, 39:1084-1090, 2004.

77. T.D. Blalock, R. Yuan, A.S. Lewin, G.S. Schultz. Hammerhead Ribozyme Targeting Connective Tissue Growth Factor mRNA Blocks Transforming Growth Factor-Beta Mediated Cell Proliferation, Exp Eye Res, 78:1127-1136, 2004.

78. R.J. Feezor, H.N. Paddock, H.V. Baker, J.C. Varela, L.L. Moldawer, G.S. Schultz, D.W. Mozingo. Temporal Patterns of Gene Expression in Murine Dermal Burn Wound Healing, Physiol Genomics, 16:341-348, 2004.

79. Q. Garrett, T.D. Blalock, P.T. Khaw, G.S. Schultz, G.R. Grotendorst, J.T. Daniels. CTGF is Involved in TGF-β1-Stimulation of Myofibroblast Differentiation and Collagen Matrix Contraction in the Presence of Mechanical Stress. Invest Ophthalmol Vis Sci, 45:1109-1116, 2004.

80. P. Bezwada, L. Clark, S. Adams, T. O’Brien, G. Schultz. Comparative Ocular Bioavailability and Efficacy of Topical Levofloxacin and Ofloxacin in Rabbits, J Toxicol Cutaneous Ocular Toxicol, 23:83-90, 2004.

81. L. Clark, P. Bezwada, K. Hosoi, T. Ikuse, S. Adams, G. Schultz, T. O’Brien. Comprehensive Evaluation of Ocular Toxicity of Levofloxacin in Rabbit and Primate Models, J Toxicol Cutaneous Ocular Toxicol, 23:1-18, 2004.

82. D.W. Esson, A. Neelakantan, A.A. Iyer, T.D. Blalock, L. Balasubramanian, G.R. Grotendorst, G.S. Schultz, M.B. Sherwood. Expression of Connective Tissue Growth Factor After Glaucoma Filtration Surgery in a Rabbit Model, Invest Ophthalmol Vis Sci, 45:485-491, 2004.

83. F.J. Ollivier, D.E. Brooks, G.S. Schultz, T.D. Blalock, S.E. Andrew, A.M. Komaromy, T.J. Cutler, M.E. Lassaline, M.E. Kallberg, G.B. van Setten. Connective Tissue Growth Factor in Tear Film of the Horse: Detection, Identification and Origin, Graefe’s Archiv Clin Exp Ophthalmol, 242:165-171, 2004.

84. F.J. Ollivier, D.E. Brooks, M.E. Kallberg, A.M. Komaromy, M.E. Lassaline, S.E. Andrew, K.N. Gelatt, G.R. Stevens, T.D. Blalock, G.B. van Setten, G.S. Schultz. Evaluation of Various Compounds to Inhibit Activity of Matrix Metalloproteinases in the Tear Film of Horses With Ulcerative Keratitis, Am J Vet Res, 64:1081-1087, 2003.

85. J.G. Wilmoth, P.J. Antonelli, G.S. Schultz. Tympanic Membrane Metalloproteinases Inflammatory Response, Otolaryngol Head Neck Surg, 129:647-654, 2003.

86. S.O. Canapp Jr., J.P. Farese, G.S. Schultz, S. Gowda, A.M. Ishak, S.F. Swaim, J. Van Gilder, L. Lee-Ambrose, F.G. Martin. The Effect of Topical Tripeptide-Copper-Complex on Healing of Ischemic Open Wounds, Vet Surgery, 32:515-523, 2003.

87. K.C. Flanders, C.D. Major, A. Arabshahi, E.D. Aburime, K.H. Okada, K. Fujii, T.D. Blalock, G.S. Schultz, A. Sowers, M.A. Anzano, J.B. Mitchell. A. Russo, A.B. Roberts. Interference with TGFb/SMAD3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin, Am J Pathol, 163:2247-2257, 2003.

88. G.A. Chin, T.G. Thigpin, K.J. Perrin, L.L. Moldawer, G.S. Schultz. Treatment of Chronic Ulcers in Diabetic Patients with a Topical Metalloproteinase Inhibitor, Doxycycline, Wounds, 15:315-323, 2003.

89. J.T. Daniels, G.S. Schultz, T.D. Blalock, Q. Garrett, G.R. Grotendorst, N.M. Dean, P.T. Khaw. Mediation of TGF1-Stimulated Contraction of Matrix Contraction by Fibroblasts: A Role for CTGF in Contractile Scarring, Am J Pathol, 163:2043-2052, 2003.

90. H.N. Paddock, G.S. Schultz, H.V. Baker, J.C. Varela, E.A. Beierle, L.L. Moldawer, D.W. Mozingo. Analysis of Gene Expression Patterns in Human Post-Burn Hypertrophic Scars, J Burn Care Rehap, 24:371-377, 2003.

91. J.G. Wilmoth, P.J. Antonelli, G.S. Schultz. Matrix Metalloproteinases in a Gerbil Cholesteatoma Model, Otolaryngol Head Neck Surg, 129:402-407, 2003.

92. P.J. Antonelli, G.S. Schultz, D.J. Sundin, P.A. Pemberton, P.J. Barr. Protease Inhibitors Alpha-1 Antitrypsin and Ilomastat Are Not Ototoxic in the Chinchilla, Laryngoscope, 113:1764-1769, 2003.

93. P. Antonelli, G. S. Schultz, K.M. Kim, J.S. Cantwell, D.J. Sundin, P.A. Pemberton, P.J. Barr. Alpha 1-Antitrypsin and

Page 6 of 38

Ilomastat Inhibit Inflammatory Proteases Present In Human Middle Ear Effusions, Laryngoscope, 113:1347-1351, 2003.

94. G.B. van Setten, M. Aspiotis, T.D. Blalock, G. Grotendorst, G.S. Schultz. Connective Tissue Growth Factor in Pterygium: Simultaneous Presence with Vascular Endothelial Cell Growth Factor – Possible Contributing Factor to Conjunctival Scarring, Graefe’s Arch Clin Exp Ophthalmol, 241:135-139, 2003.

95. R. Lobmann, G Schultz, H. Lehnert. Molekulare Grundlagen der Wundheilung bei diabetishchen Fußsytndrom, Medizinische Klinik, 98:292-301, 2003.

96. J.T. Daniels, A.D. Cambrey, N.L. Occleston, Q. Garrett, R.W. Tarnuzzer, G.S. Schultz, P.T. Khaw. Matrix Metalloproteinase Inhibition Modulates Fibroblast-Mediated Matrix Contraction and Production In Vitro, Invest Ophthalmol Vis Sci, 44:1104-1110, 2003.

97. M.K. Mazaheri, G.S. Schultz, T.D. Blalock, H.H. Caffee, G.A. Chin. Role of Connective Tissue Growth Factor in Breast Implant Elastomer Capsular Formation, Ann Plastic Surg, 50:1-6, 2003.

98. M.F. Cordeiro A. Mead, R.R. Ali, R.A. Alexander, S. Murray, C. Chen, C. York-Defalco, N.M. Dean, G.S. Schultz, P.T. Khaw. Novel Antisense Oligonucleotides Targeting TGF-Beta Inhibit In Vivo Scarring And Improve Surgical Outcome, Gene Therapy, 10:59-71, 2003.

99. G.B. van Setten, T.D. Blalock, G. Grotendorst, G.S. Schultz. Detection of Connective Tissue Growth Factor (CTGF) in Human Tear Fluid: Preliminary Results, Acta Ophthalmologica Scand 81:51-53, 2003.

100. T.D. Blalock, M.R. Duncan, J.C. Varela, M.H. Goldstein, S. Tuli, G. Grotendorst, G.S. Schultz. Connective Tissue Growth Factor Expression and Action in Human Corneal Fibroblasts Cultures and Rat Corneas Following Photorefractive Keratectomy, Invest Ophthalmol Vis Sci, 44:1879-1887, 2003.

101. R.R. Mohan, G.S. Schultz, J.W. Hong, R.R. Mohan, S.E. Wilson. Gene Transfer Into Rabbit Keratocytes Using AAV and Lipid-Mediated Plasmid Vectors With a Lamellar Flap for Stromal Access, Exp Eye Res, 76:373-383, 2003.

102. G.B. van Setten, T.D. Blalock, G.R. Grotendorst, G.S. Schultz. Detection of Connective Tissue Growth Factor in Human Aqueous Humor, Ophthalmic Res, 34:306-308, 2002.

103. R. Lobmann, A. Ambrosch, G. Schultz, K. Waldmann, S. Schieweck, H. Lehnert. Expression of Matrix-Metalloproteinases and Their Inhibitors in the Wounds of Diabetic and Non-Diabetic Patients, Diabetologia, 45:1011-1016, 2002.

104. J.C. Varela, M.H. Goldstein, H.V. Baker, G.S. Schultz. Microarray Analysis of Gene Expression Patterns During Healing of Rat Corneas After Excimer Laser Photorefractive Surgery, Invest Ophthalmol Vis Sc,i 43:1772-1782, 2002.

105. G.P. Ladwig, M.C. Robson, R. Liu, M.A. Kuhn, D.F. Muir, G.S. Schultz. Ratios of Activated MMP-9/TIMP-1 in Wound Fluids Are Inversely Correlated With Healing of Pressure Ulcers, Wound Repair Regen, 4:26-37, 2002.

106. D.H. Lehman, P.J. Antonelli, J.G. Wilmoth, A.R. Prevatt, G.S. Schultz. Inhibition of Matrix Metalloproteinases in Gerbil Cholesteatoma, Otolaryngol Head Neck Surg, 126:404-408, 2002.

107. A.J. Cowin, N. Hatzirodos, C.A. Holding, V. Dunaiski, R.H. Harries, T.E. Rayner, R. Fitridge, R.D. Cooter, G.S.

Schultz D.A. Belford. Effect of Healing on the Expression of Transforming Growth Factor-s and Their Receptors in Chronic Venous Leg Ulcers, J Invest Dermatol, 117:1282-1289, 2001.

108. G.L. Locksmith, P. Clark, P. Duff, G.R. Saade, G.S. Schultz. Amniotic Fluid Concentrations of Matrix Metalloproteinase 9 and Tissue Inhibitor of Metalloproteinase 1 During Pregnancy and Labor, Am J Obstet Gynecol, 184:159-164, 2001.

109. N. Dushku, M.K. John, G.S. Schultz, T.W. Reid. Pterygia Pathogenesis: Corneal Invasion by Matrix Metalloproteinase Expressing Altered Limbal Epithelial Basal Cells and Activation of Fibroblasts, Arch Ophthalmol, 119:695-706, 2001.

110. D.T. Strubbe, D.E. Brooks, G.S. Schultz, H. Willis-Goulet, K.N. Gelatt, S.E. Andrew, M.E. Kallberg, E.O. Mackay, W.R. Collante. Evaluation of Tear Film Proteinases in Horses with Ulcerative Keratitis, Vet Ophthalmol, 3:111-119, 2000

111. C. Chen, B. Michelini-Norris, S. Stevens, J. Rowsey, X. Ren, M. Goldstein, G.S. Schultz. Quantitative Measurement

of mRNAs for Transforming Growth Factor-and Extracellular Matrix Proteins in Rat Corneas After Excimer Laser Keratectomy, Invest Ophthalmol Vis Sci, 41:4108-4116, 2000.

112. G.J. Angella, M.B. Sherwood, L. Balasubramanian, W. Doyle, M.F. Smith, G. van Setten, M. Goldstein, G.S. Schultz. Collagen Shield Enhances Plasmid Transfection of Filtration Surgery Tissues, Invest Ophthalmol Vis Sci, 41: 4158-4162, 2000.

113. V.C. Mudera, R. Pleass, M. Eastwood, R. Tarnuzzer, G. Schultz, P. Khaw, D.A. McGrouther, R.A. Brown. Molecular Responses of Human Dermal Fibroblasts to Dual Cues: Contact Guidance and Mechanical Load, Cell Motility Cytoskeleton, 45:1-9, 2000.

114. M.F. Cordeiro, S.S. Bhattacharya, G.S. Schultz, P.T. Khaw. TGF-ß1, -ß2 & -ß3 In Vitro: Biphasic Effects on Tenon's Fibroblast Contraction, Proliferation & Migration, Invest Ophthalmol Vis Sci, 41:756-763, 2000.

115. Y.T. Konttinen, P. Kemppinen, T.F. Li, H. Pihlajamki, T. Sorsa, M. Takagi, S. Santavirta, G.S. Schultz, M.G. Humphreys-Beher. Transforming and Epidermal Growth Factors in Degenerated Intervertebrate Discs, J Bone Joint Surg, 81:1058-1063, 1999.

116. C. Chen, G.S. Schultz, M. Bloch, P.D. Edwards, S. Tebes, D. Mills, B.A. Mast. Molecular and Mechanistic Validation

Page 7 of 38

of Delayed Healing Rat Wounds as a Model for Human Chronic Wounds, Wound Repair Regen, 7:486-494, 1999. 117. G.J. Locksmith, P. Clark, P. Duff, G.S. Schultz. Amniotic Fluid Matrix Metalloproteinase-9 Levels in Women with

Preterm Labor and Suspected Intra-amniotic Infection, Obstet Gynecol, 94:1-6, 1999. 118. M. John, G. Schultz, T.N. Rajaleksbmi, M.B. Nair. Immunolocalization and Quantitation of Transforming Growth

Factor alpha in Hydatidiform Moles, Tumori, 85:179-183, 1999. 119. B.K. Pilcher, J. Dunin, B.A. Mast, G.S. Schultz, W.C. Parks, H.G. Welgus. Keratinocyte Collagenase-1 Expression

Requires an Epidermal Growth Factor Receptor Autocrine Mechanism, J Bio Chem, 274:10372-10381, 1999.

120. G.B. van Setten, L. Edström, H. Stibler, S. Rasmussen, G. Schultz. Levels of Transforming Growth Alpha (TGF-) in Human Cerebrospinal Fluid, Int J Dev Neuroscience, 17:131-134, 1999.

121. N.J. Trengove, M.C. Stacey, S. Macauley, N. Bennett, J. Gibson, F. Burslem, G. Murphy, G. Schultz. Analysis of Acute and Chronic Wound Environments: The Role of Proteases and their Inhibitors, Wound Repair Regen, 7:442-452, 1999.

122. S. Tomas-Barberan, G.S. Schultz, R.W. Tarnuzzer, P. Fagerholm. Messenger RNA Levels of Genes Involved in Extracellular Matrix From Human Corneal Scrapings Before and After Photorefractive Keratectomy, Acta Ophthalmol Scandinavia, 76:568-572, 1998.

123. M.B. Witte, F.J. Thornton, T. Kiyama, D.T. Efron, G.S. Schultz, L.L. Moldawer, A. Barbul. Metalloproteinase Inhibitors and Wound Healing: A Novel Enhancer of Wound Strength, Surgery, 124:464-470, 1998.

124. M.A. Avidano, C.S. Cotter, S.P. Stringer, G.S. Schultz. Analysis of Protease Activity in Human Otitis Media, Otolaryngology Head Neck Surg, 119:346-351, 1998.

125. Dou, R.W. Tarnuzzer, R.S. Williams, G.S. Schultz, N. Chegini. Differential Expression of Matrix Metalloproteinase and Their Tissue Inhibitors in Leiomyomata: A Mechanism for Gonadotropin Releasing Hormone Agonist-Induced Tumor Regression, Molecular Human Reprod, 3:1005-1014, 1997.

126. J.W. Doyle, M.F. Smith, J.T. Garcia, G. Schultz M.B. Sherwood. Treatment of Bleb Leaks with Transforming Growth

Factor- in the Rabbit Model, Invest Ophthalmol Vis Sci, 38:1630-1634, 1997. 127. C.C. Solorzano, R. Ksontini, J.H. Pruitt, T. Auffenberg, C. Tannahill, R.E. Galardy, G.S. Schultz, S.L.D. MacKay,

E.M. Copeland, III, L.L. Moldawer. A Matrix Metalloproteinase Inhibitor Prevents Processing of Tumor Necrosis

Factor Alpha (TNF) and Abrogates Endotoxin-Induced Lethality, Shock, 7:427-431, 1997. 128. P. Balarm, M. John, T.N. Rajalekshmy, B. Nair, G. Schultz, K. Nair. Expression of Epidermal Growth Factor in

Gestational Trophoblastic Diseases, J Cancer Res Clin Oncol, 123: 161-166,1997. 129. M. John, T.N. Rajalekshmy, B. Nair, J. Augustine, G. Schultz, K.M. Nair, P. Balaram. Expression of Epidermal

Growth Factor and its Receptor in Gestational Trophoblastic Diseases, Oncology Reports, 4:177-182,1997. 130. N.L. Occleston, J.T. Daniels, R.W. Tarnuzzer, K.K. Sethi, R.A. Alexander, S.S. Bhattacharaya, G.S. Schultz, P.T.

Khaw. Single Exposure to Antiproliferatives: Long-Term Effects on Ocular Fibroblast Wound Healing Behavior, Invest Ophthalmol Vis Sci, 38:1998-2007, 1997.

131. G.S. Ashcroft, M.A. Horan, R.W. Tarnuzzer, G.S. Schultz, M.A. Horan, M.W.J. Ferguson. Estrogen Accelerates

Cutaneous Wound Healing Associated with an Increase in TGF-1 Levels, Nature Medicine, 3:1209-1215, 1997. 132. G.S. Ashcroft, S.E. Herrick, R.W. Tarnuzzer, G.S. Schultz, M.A. Horan, M.W.J. Ferguson. Age-Related Changes in

the Temporal and Spatial Regulation of Matrix Metalloproteinases (MMP) Protein and mRNA Profiles in Normal Skin and Acute Cutaneous Wounds of Healthy Humans, Cell Tissue Res, 290:581-591, 1997.

133. G.S. Ashcroft, S.E. Herrick, R.W. Tarnuzzer, M.A. Horan, G. Schultz, M.W.J. Ferguson. Human Ageing Impairs Injury-Induced in Vivo Expression of Tissue Inhibitors of Matrix Metalloproteinases (TIMP)-1 and -2 Proteins and mRNA, J Pathol, 183:169-176, 1997.

134. C.C. Solórzano, S.C. Jones, M. Pettijean, T.G. O'Daniel, T. Auffenberg, P.G. Woost, E.M. Copeland, III, G.S. Schultz, S.L.D. MacKay. Inhibition of Transforming Growth Factor Alpha Stimulation of Human Squamous Cell

Carcinoma of the Head and Neck with Anti-TGF- Antibodies and Tyrphostin, Ann Surg Oncol, 4:670-684,1997. 135. L.E. Franzen, M.R. Ghassenifar, B. Lonnberg, G.S. Schultz. Stimulation Of Protracted Connective Tissue Repair In

Normal Mice By Transforming Growth Factor 1, Scand J Plast Reconstr Hand Surg, 30:267-273, 1996. 136. M.R. Ghassemifar, R.W. Tarnuzzer, N. Chegini, E. Tarila, G.S. Schultz, L.E. Franzen. Expression of Alpha-Smooth

Muscle Actin, TGF-1, and TGF- Type II Receptor mRNA During Connective Tissue Contraction, In Vitro Cell Dev Biol, 33:622-627, 1997.

137. S.P. Macauley, R.W. Tarnuzzer, G.S. Schultz, N. Chegini, G.E. Oxford, M.G. Humphreys-Beher. Extracellular-Matrix Gene Expression During Mouse Submandibular Gland Development, Arch Oral Biol, 42:443-454, 1997.

138. Q. Dou, Y. Zhao, R.W. Tarnuzzer, H. Rong, R.S. Williams, G.S. Schultz, N. Chegini. Suppression of Transforming

Growth Factor-Beta (TGF- ) and TGF-Receptor Messenger Ribonucleic Acid and Protein Expression in Leiomyomata in Women Receiving Gonadotropin-Releasing Hormone Agonist Therapy, J Clin Endocrinol Metab, 81:3222-3230, 1996.

139. S.P. Macauley, G.S. Schultz, B.A. Buckner, J.L. Laz, S.A. Krawetz, T.P. Yang. Effects of Transforming Growth Factor Alpha on Extracellular Matrix Gene Expression by Human Fibroblasts From a Laryngeal Stenotic Lesion, Wound Repair Regen, 4:269-277, 1996.

140. C.S. Cotter, M.A. Avidano, S.P. Stringer, G.S. Schultz. Experimental Inhibition of Proteases in Pseudomonas Otitis Media in Chinchillas, Otolaryngol Head Neck Surgery, 115:342-251, 1996.

Page 8 of 38

141. R.W. Tarnuzzer, S.P. Macauley, W.G. Farmerie, S. Cabellaro, M.R. Ghassemifar, J.T. Anderson, C.R. Robinson, M.B. Grant, M.G. Humphreys-Beher, L. Franzen, A.B. Peck, G.S. Schultz. Competitive RNA Templates for Detection and Quantification of Growth Factors, Cytokines, Extracellular Matrix Components, and Matrix Metalloproteinases by RT-PCR, Biotechniques, 20:670-674, 1996.

142. J.P. Barletta, G.J. Angella, K.C. Balch, H.G. Dimova, G.A. Stern, M.T. Moser, G.B. van Setten G.S. Schultz. Inhibition of Pseudomonal Ulceration in Rabbit Corneas by a Synthetic Matrix Metalloproteinase Inhibitor, Invest Ophthalmol Vis Sci, 37:20-28, 1996.

143. G.B. van Setten, S.P. Macauley, M. Humphreys-Beher, N. Chegini G. Schultz. Detection of Transforming Growth

Factor- mRNA and Protein in Rat Lacrimal Glands and Characterization of Transforming Growth Factor- in Human Tears, Invest Ophthalmol Vis Sci, 37:166-173, 1996.

144. A.V. Nall, R.E. Brownlee, C.P. Colvin, G.S. Schultz, D. Fein, T Lui, A. Kalra, N.J. Cassisi. Transforming Growth Factor Beta-1 Improves Wound Healing and Random Flap Survival in Normal and Irradiated Rats, Arch Otolaryngol Head Neck Surg, 122:171-177, 1996.

145. G.B. van Setten, P. Fagerholm, B. Philipson, G. Schultz. Growth Factors and Their Receptors in the Anterior Chamber – Absence of Epidermal Growth Factor and Transforming Growth Factor Alpha in Human Aqueous Humor, Ophthalmic Res, 28:361-364, 1996.

146. Nilsson, B. Wangberg, L. Kolby, G.S. Schultz, H. Ahlman. Expression of Transforming Growth Factor alpha and Its Receptor in Human Neuroendocrine Tumors, Int J Cancer, 60:645-651, 1995.

147. K.R. Purushotham, K. Offenmüller, A.T. Bui, T. Zelles, J. Blazsek, G.S. Schultz, M.G. Humphreys-Beher. Absorption of Epidermal Growth Factor Occurs Through the Gastrointestinal Tract and Oral Cavity in the Adult Rat, A J Physiol, 269:G867-G873, 1995.

148. S.L.D. MacKay, L.R. Yaswen, R.T. Tarnuzzer, L.L. Moldawer, K.I. Bland, E.M. Copeland G.S. Schultz. Colon

Cancer Cells That Are Not Growth Inhibited by TGF- Lack Functional Type I and II TGF- Receptors, Ann Surg, 221:767-777, 1995.

149. G.B. van Setten G.S. Schultz. Transforming Growth Factor Alpha is a Constant Component of Human Tear Fluid, Graefe's Archiv Clin Exp Ophthalmol, 232:523-526, 1994.

150. S.E. Wilson, Y-G. He, J. Weng, J.D. Zeiske, J.V. Jester, G.S. Schultz. Effect of Epidermal Growth Factor, Hepatocyte Growth Factor, and Keratinocyte Growth Factor on Proliferation, Motility and Differentiation of Human Corneal Epithelial Cells, Exp Eye Res, 59:665-678, 1994.

151. P. Malcherek, G. Schultz, U. Wingren, L. Franzen. Formation of Healing Tissue and Angiogenesis in Repair of Connective Tissue Stimulated by Epidermal Growth Factor, Scan J Plast Reconstr Hand Surg, 28:1-7, 1994.

152. S.E. Wilson, G.S. Schultz, N. Chegini, J. Weng, Y.G. He. Epidermal Growth Factor, Transforming Growth Factor Alpha, Transforming Growth Factor Beta, Acidic Fibroblast Growth Factor, Basic Fibroblast Growth Factor, and Interleukin-1 Proteins in the Cornea, Exp Eye Res, 59:63-72, 1994.

153. M.G. Humphreys-Beher, S.P. Macauley, N. Chegini, G.B. van Setten, K. Purushotham, C. Stewart, T.T. Wheeler,

G.S. Schultz. Characterization of the Synthesis and Secretion of TGF- from Salivary Glands and Saliva, Endocrinology, 134:963-970, 1994.

154. D.S. Rotatori, N.C. Kerr, B. Raphael, B.J. McLaughlin, G.A. Stern, G.S. Schultz. Transforming Growth Factor Alpha in Cat Anterior Chamber Fluid After Endothelial Injury, Invest Ophthalmol Vis Sci, 35:143-149, 1994.

155. P. Malcherek, G. Schultz, U. Wingren, L. Franzen. Effect of Epidermal Growth Factor on Cell Proliferation in Normal and Wounded Connective Tissue, Wound Repair Regen, 1:63-68, 1993.

156. J.D. King, S.P. Stringer, N. Chegini, W.H. Donnelly, N.J. Cassisi, G.S. Schultz. Transforming Growth Factor Alpha Protein and Receptor Localization in Normal and Healing Laryngotracheal Tissue, Otolaryngol Head Neck Surg, 109:915-925, 1993.

157. B. Raphael, N.C. Kerr, R.W. Shimizu, J.H. Lass, K.C. Crouthamel, S.R. Glaser, G.S. Schultz, B.J. McLaughlin, D.C. Musch. Enhanced Healing of Cat Corneal Endothelial Wounds by Epidermal Growth Factor, Invest Ophthalmol Vis Sci, 34:2305-2312, 1993.

158. R.M. Salloum, G.S. Schultz, W.W. Souba. Regulation of Small Intestinal Substrate Transport by Epidermal Growth Factor, Surgery, 113:552-559, 1993.

159. L. Franzen, R. Ghassenifar, G. Schultz. Specific Binding of EGF in Connective Tissue Repair, Euro J Cell Biol, 60:346-350, 1993.

160. P.T. Khaw, J.W. Doyle, M.B. Sherwood, I. Grierson, S. McGorray, G. Schultz. Prolonged Localized Tissue Effects from 5-Minute Exposures to 5-Fluorouracil and Mitomycin-c, Arch Ophthalmol, 111:263-267, 1993.

161. N. Chegini, M.J. Rossi, G.S. Schultz, W.A. Dunn, Jr., B.J. Masterson. Cellular Distribution of EGF, TGF- and EGF Receptor in Fascia Peritoneum During Healing: an Autoradiographic and Immunohistochemical Study, Wound Repair Regen, 1:28-40, 1993.

162. P.T. Khaw, M.B. Sherwood, J.W. Doyle, M.F. Smith, I. Grierson, S. McGorray, G.S. Schultz. Intraoperative and Postoperative Treatment with 5-Fluorouracil and Mitomycin-C: Long Term Effects In Vivo on Subconjunctival and Scleral Fibroblasts, International Ophthalmol, 16:381-385, 1992.

163. G.S. Schultz, S. Strelow, G.S. Stern, N. Chegini, M.B. Grant, R.E. Galardy, D. Grabelny, J.J. Rowsey, C. Stonecipher, V. Parmley. Inhibition of Cornea Ulceration After Severe Alkali Injury by a Synthetic Metalloproteinase

Page 9 of 38

Inhibitor. Invest Ophthalmol Vis Sci, 33:3325-3331, 1992. 164. M.B. Grant, P.T. Khaw, G.S. Schultz, J.L. Adams, R.W. Shimizu. Effects of Epidermal Growth Factor, Fibroblast

Growth Factor and Transforming Growth Factor Beta on Corneal Cell Chemotaxis, Invest Ophthalmol Vis Sci, 33:3292-3301, 1992.

165. P.T. Khaw, S.L.D. MacKay, N. Chegini, G.S. Schultz. Detection of Transforming Growth Factor- Messenger RNA and Protein in Human Corneal Epithelial Cells, Invest Ophthalmol Vis Sci, 33:3302-3306, 1992.

166. J.S. Sanfilippo, Ch.V. Rao, J.J. Guarnaschelli, P.G. Woost, V.M. Byrd, E. Jones, G.S. Schultz. Detection of Epidermal Growth Factor and Transforming Growth Factor Alpha Protein in Meningiomas and Other Tumors of the Central Nervous System in Human Beings, Surg Gynecol Obstet, 177:488-496, 1993.

167. P.T. Khaw, M.B. Sherwood, S.L.D. MacKay, M.J. Rossi, G. Schultz. Five-Minute Treatments with Fluorouracil, Fluorouridine and Mitomycin Have Long-term Effects on Human Tenon's Fibroblasts, Arch Ophthalmol, 110:1150-1154, 1992.

168. F. Bissionnette, C. Cook, T. Geoghegan, M. Steffan, J. Henry, M.A. Yussman, G. Schultz. Transforming Growth Alpha and Epidermal Growth Factor mRNA and Protein Levels in Early Mid and Late Gestation Human Placenta, Am J Obstet Gynecol, 166:192-199, 1992.

169. U. Wingren, L. Franzen, G.M. Larson, P. Malcherak, G.S. Schultz. Epidermal Growth Factor Accelerates Connective Tissue Wound Healing in the Perforated Rat Mesentery, J Surg Res, 52:48-54, 1992.

170. S.C. Jones, L.J. Curtsinger, J.D. Whalen, J.D. Pietsch, D. Ackerman, G.L. Brown, G.S. Schultz. Effect of Topical

Recombinant TGF- on Healing of Partial Thickness Injuries, J Surg Res, 51:344-352, 1991. 171. R.S. Williams, G.S. Schultz, N. Chegini, A.M. Rossi. Effect of Transforming Growth Factor Beta on Post Operative

Adhesions Formation and Intact Peritoneum, J Surg Res, 52:65-70, 1992. 172. G.S. Schultz, L. Cipollo, A. Whitehouse, R.A. Eiferman, P. Woost, M. Jumblatt. Growth Factors and Corneal

Endothelial Cells: III. Stimulation of Adult Human Corneal Endothelial Cell Mitosis in Vitro by Defined Mitogenic Agents, Cornea, 11:20-27, 1992.

173. P.G. Woost, M.M. Jumblatt, R.A. Eiferman, G.S. Schultz. Growth Factors and Corneal Endothelial Cells: II. Characterization of Epidermal Growth Factor Receptor from Bovine Corneal Endothelial Cells, Cornea, 11:11-19, 1992.

174. P.G. Woost, M. M. Jumblatt, R.A. Eiferman, G.S. Schultz. Growth Factors and Corneal Endothelial Cells: I. Stimulation of Bovine Corneal Endothelial Cell DNA Synthesis in Defined Growth Factor, Cornea, 11:1-10, 1992.

175. G.L. Brown, L.J. Curtsinger, M.J. Jurkiewicz, G.S. Schultz. Stimulation of Healing of Chronic Wounds by Epidermal Growth Factor, Plastic Reconstr Surgery, 88:189-196, 1991.

176. T.G. O'Daniel, M. Petitjean, J. Zogg, J.K. Lasseter, S.A. Martinez, M.B. Nolph, G.S. Schultz. Characterization of Epidermal Growth Factor Binding and Action on Tympanic Membranes, Ann Otol Rhinol Laryngol, 99:80-84, 1990.

177. D.S. Rotatori, H.H. Caffee, E.M. Copeland, G.S. Schultz. Growth Factors are Present in Human Wound Fluid, Surgical Forum, 41: 627-630, 1990.

178. J.S. Thompson, S.K. Saxena, C. Greaton, G. Schultz, J.G. Sharp. The Effect of the Route of Delivery of Urogastrone on Intestinal Regeneration, Surgery, 106:45-51, 1989.

179. J.B. Fassio, E.B. Brockman, M. Jumblatt, C. Creaton, J.I. Henry, T.E. Georghegan, C.C. Barr, G.S. Schultz. Transforming Growth Factor Alpha and Its Receptor In Neural Retina, Invest Ophtholomol Vis Sci, 30:1916-1922, 1989.

180. G.L. Brown, L.B. Nanney, J. Griffen, A.B. Cramer, J.M. Yancey, L.J. Curtsinger, L. Holtzin, G.S. Schultz, M.J. Jurkiewicz, J.B. Lynch. Enhancement of Wound Healing by Topical Treatment With Epidermal Growth Factor, New Eng J Med, 321:76-79, 1989.

181. M.J. Brown, J.L. Zogg, G.S. Schultz, F.K. Hilton. Increased Binding of Epidermal Growth Factor at Implantation Sites in Mouse Uteri, Endocrinology, 124:2882-2888, 1989.

182. L.J. Curtsinger, J.D. Pietsch, G.L. Brown, A. von Fraunhofer, D. Ackerman, H.C. Polk, Jr., G.S. Schultz. Reversal of

Adriamycin-Impaired Wound Healing by TGF-Surgery Gyn Obstet, 168:517-522, 1989.

183. S.C. Jones, G.S. Schultz, S.A. Martinez. Characterization of Transforming Growth Factor- Binding and Action on Squamous Cell Carcinoma Cells, Surgical Forum, 40: 533-535, 1989

184. G.L. Brown, L.J. Curtsinger, M. White, R.O. Mitchell, J. Pietsch, R. Nordquist, A. von Fraunhofer, G.S. Schultz.

Acceleration of Tensile Strength of Incisions Treated with EGF and TGF-Ann Surg, 208:788-794, 1988. 185. G.E. Hofmann, C.V. Rao, M.J. Brown, L.F. Murray, G.S. Schultz, T.A. Siddigi. Human Epidermal Growth Factor

Concentrations in Urine of Nonpregnant and Pregnant Women Throughout Pregnancy and at Delivery, J Clin Endocrinol Metab, 66:119-123, 1988.

186. K. Darlak, G. Franklin, P. Woost, E. Sonnenfeld, D. Twardzik, A. Spatola, G.S. Schultz. Assessment of Biological

Activity of Synthetic Fragments of Transforming Growth Factor-J Cell Biochem, 36:341-352, 1988. 187. S.C. Jones, C.J. Greaton, M. Pettijean, S.A. Martinez, G.S. Schultz. Regulation of Squamous Cell Carcinoma Cell

Growth By Transforming Growth Factor- and Epidermal Growth Factor, Surgical Forum, 39: 548-550, 1988. 188. U. Wingren, G.M. Larson, C.J. Greaton, G.S. Schultz. Intravenous But Not Intragastric Epidermal Growth Factor

Inhibits Acid Secretion, Surgical Forum, 39: 75-77, 1988. 189. L.J. Curtsinger, J.D. Pietsch, G.S. Schultz, G.L. Brown, H.C. Polk. Reversal of Adriamycin-Impaired Wound Healing

Page 10 of 38

By Transforming Growth Factor Beta, Surgical Forum, 38: 608-610, 1988 190. I.H. Silverman, C.L. Cook, J.S. Sanfilippo, M.A. Yussman, G.S. Schultz F.K. Hilton. Ham's F-10 Constituted with Tap

Water Supports Mouse Conceptus Development In Vitro, J In Vitro Fert, 4:185-187, 1987. 191. G.S. Schultz, M. White, G. Brown, J. Lynch, D.R. Twardzik, G. J. Todaro. Epithelial Wound Healing Enhanced by

Transforming Growth Factor- and Vaccinia Growth Factor, Science, 235:350-352 1986. 192. N.A. Muma, P.R. Rowell, G.S. Schultz. Effects of Long-Term Dietary Choline and Phosphatidylcholine

Administration on Muscarinic Receptors in Aged Mouse Brain, Neurolog Res, 10:130-135, 1988. 193. M.J. Brown, C.L. Cook, J.L. Henry, G.S. Schultz. Levels of Epidermal Growth Factor Binding in Third Trimester and

Term Human Placenta: Elevated Binding in Term Placentas of Male Fetuses, Am J Obstet Gynecol, 156:716-720, 1987.

194. M. Petitjean, C.J. Greaton, S.A. Martinez, T.E. Geoghegan, G.S. Schultz. Production of Transforming Growth

Factor- in Head and Neck Carcinomas, Surgical Forum, 38: 574-576, 1987. 195. N. Ramani, N. Chegini, C.V. Rao, P. Woost, G.S. Schultz. The Presence of Epidermal Growth Factor Binding Sites

in the Intracellular Organelles of Term Placenta, J Cell Sci, 84:19-40, 1986. 196. F. DeLeon, R. Vijayakumar, M. Brown, C.V. Rao, M.A. Yussman, G.S. Schultz. Peritoneal Fluid Estrogen,

Progesterone, PGF2 , PGE2, and Epidermal Growth Factor in Patients With or Without Endometriosis, Obstet Gynecol, 62:189-194 1986.

197. G. Brown, J. Brightwell, L. Curtsinger, H. Polk, J. Merryweather, P. Valenzuela, G. Schultz. Enhancement of Epidermal Regeneration by Biosynthetic Epidermal Growth Factor, J Exp Med, 163:1319-1324, 1986.

198. T. O'Daniel, S. Martinez, G. Schultz, J. Lassetter, P. Woost, S. Jones, K. Walker. Epidermal Growth Factor Receptors in Head and Neck Tumors, Surgical Forum 37: 568-570, 1986.

199. C.V. Rao, N. Ramani, N. Chegini, F. Carman, B. Stadig, P. Woost, G. Schultz, C. Cook. Topography of Human Placental Binding Sites for Epidermal Growth Factor, J Biol Chem, 260:1705-1710, 1985.

200. P.G. Woost, J. Brightwell, R.A. Eiferman, G.S. Schultz. Effect of Growth Factors with Dexamethasone on Corneal Stromal Wound Healing, Exp Eye Res, 40:47-60, 1985.

201. J. Brightwell, R.A. Eiferman, P. Valenzuela, P.J. Barr, J.P. Merryweather, G.S. Schultz. Biosynthetic human EGF accelerates healing of Neodecadron-treated primate corneas, Invest Ophthalmol Vis Sci, 26:105-110, 1985.

202. L.J. Curtsinger, III, G.S. Schultz, G.L. Brown. Progress in Burn Therapy: Skin Banking and Epidermal Culture, J. Kentucky Med Assoc, pp. 251-253, 1985.

203. M.J. Brown, G.S. Schultz, F.K. Hilton. Intrauterine Proximity to Male Fetuses Predetermines Level of Epidermal Growth Factor in Submandibular Glands of Adult Female Mice, Endocrinology, 115:2318-2323, 1984.

204. C.V. Rao, F.R. Carman, N. Chegini, G.S. Schultz. Binding Sites for Epidermal Growth Factor in Human Fetal Membranes, J Clin Endocrinol Metab, 58:1034-1042, 1984.

205. S.L. Fitzpatrick, J. Brightwell, J.L. Wittliff, G.H. Barrows, G.S. Schultz. Epidermal Growth Factor Receptors in Breast Tumor Biopsies: Relationship to Estrogen Receptor Levels, Cancer Res, 44:3448-3453, 1984.

206. S.L. Fitzpatrick, M.P. LaChance, G.S. Schultz. Characterization of Epidermal Growth Factor Receptor and Action on Human Breast Cancer Cells in Culture, Cancer Res, 44:3442-3447, 1984.

207. G.E. Hofmann, C.V. Rao, G.H. Barrows, G.S. Schultz, J.S. Sanfilippo. Binding Sites for Epidermal Growth Factor in Human Uterine Tissues and Leiomyomas, J Clin Endocrinol Metab, 58:880-884, 1984.

208. J.J. Miller, G.S. Schultz, R.S. Levy. Rapid Purification of Radio-iodinated Peptides with Sep-Pak Reversed Phase Cartridge and HPLC, Intl J Peptide Prot Res, 24:112-122, 1984.

209. G.L. Brown, G.S. Schultz, J.R. Brightwell, G.R. Tobin. Biosynthetic Human Epidermal Growth Factor Enhances Epithelial Regeneration, Surgical Forum, 35: 565-567, 1984.

210. G.S. Schultz, R.E. Galardy, J.D. Jamieson. Biological Activity of an Angiotensin-II-Ferritin Conjugate on Rabbit Aortic Smooth Muscle Cells, Biochemistry, 20:3412-3418, 1981.

211. G.S. Schultz, Ebner, K.E. Immunological Reactivities of Rat and Human -Lactalbumin, Compar Biochem Physiol, 67:689-692, 1980.

212. G.S. Schultz, M.P. Sarras, Jr., G.R. Gunther, B.E. Hull, F.S. Gorelick, H.A. Alicea, J.D. Jamieson. Pancreatic Acini Prepared with Purified Collagenase, Exp Cell Res, 130:49-62, 1980.

213. H.E. Ives, G.S. Schultz, R.E. Galardy, J.D. Jamieson. Preparation of Functional Smooth Muscle Cells from the Rabbit Aorta, J Exp Med, 148:1400-1412, 1978.

214. A.B. Rawitch, G.S. Schultz, K.E. Ebner, R.M. Vardaris. Competition of 9-Tetrahydrocannabinol with Estrogen in Rat Uterine Estrogen Receptor Binding, Science, 197:1189-1191, 1977.

215. G.S. Schultz, K.E. Ebner. -Lactalbumin Levels in Human Mammary Tumors, Sera and Mammary Cell Culture Lines, Cancer Res, 37:4489-4492, 1977.

216. G.S. Schultz, K.E. Ebner. Measurement of -Lactalbumin in Serum and Mammary Tumors of Rats by Radioimmunoassay, Cancer Res, 37:4482-4488, 1977.

217. B.T. Schroeder, G.S. Schultz, L.W. Walker, B.G. Hudson, K.E. Ebner. Biosynthesis of Lactose by the R3230AC Mammary Tumor in Isolated Cell Culture, Ann Okla Acad Sci, 4:96-102, 1971.

Page 11 of 38

Review Articles

1. R.J. Snyder, G. Bohn, J. Hanft, L. Harkneess, P. Kim, L. Lavery, G. Schultz, R. Wolcott . Wound Biofilm: Current Perspectives and Strategies on Biofilm Disruption and Treatments. Wounds, 29:(6 supplement) S1-S17, 2017.

2. T. Bjarnsholt, T. Eberlein, M. Malone, G. Schultz. Management of Wound Biofilm Made Easy, Wounds International, May, 2017.

3. C. Braumann, K. Lazaro-Martinez, G. Schultz, T. Swanson. Soring UAW Made Easy, Wounds International, April, 2017.

4. G. Schultz, B. Cullen. Proteases Made Easy, Wounds International, February, 2017. 5. T. Swanson, D. Angel, G. Sussman, R. Cooper, E. Haesler, K. Ousey, K. Carville, J. Fletcher, L. Kaplan, D. Keast,

D. Leaper, G. Schultz, J. Black, E. Call. International Wound Infection Institute (IWII) Wound Infection in Clinical Practice, Wounds International, 2016.

6. G.S. Schultz, D.J. Gibson, J. Lantis, G. Nakagami. Biofilm Update, Wound Practice and Research – Wounds Australia, 24:228-231, 2016.

7. P.T. Khaw, S. Brocchini, G. Georgoulas, K. Askan, G.S. Schultz. Matrix Metalloproteinases in the Eye, Progress in Retinal and Eye Research, in press.

8. R.E. Horch, G. Schultz, D. Schubert. Zur Problematik des bakteriellen Biofilms auf Brustprothesen, Plastische Chirurgie, in press

9. T. Swanson, L. Grothier, G. Schultz. Wound Infection Made Easy, Wounds International, 5:1-6, http://www.woundsinternational.com, December, 2014.

10. R.E. Horch, G. Schultz, D. Schubert, M. Schmitz. Infectious complications in alloplastic breast surgery and implications for plastic surgeons, German Plastic Reconstructive and Aesthetic Surgeons, 2014.

11. P.J. Kim, C.E. Attinger, J.S. Steinberg, K.E. Evans, B. Lehner, C. Willy, L. Lavery, T. Wolvos, D. Orgill, A. Gabriel, W. Ennis, J. Lantis, G. Schultz. Negative Pressure Wound Therapy with Instillation – Consensus Guidelines, Plastic & Reconstructive Surgery, 132:1569-1579, 2013.

12. D.J. Gibson, G.S. Schultz. Molecular Wound Assessments: Matrix Metalloproteinases, Advances in Wound Care, 3: 18-23, 2013. PM:24527319

13. D.J. Gibson and G.S. Schultz. A Corneal Scarring Model, Methods Mol Biol, 1037:277-298, 2013. PMID:24029942 14. R.E. Horch, G. Schultz, D. Schubert, M. Schmitz, C. Bogdan, J.P. Beier. Durch Biofilm bakteriell besiedelte

Implantate bedingen Wundheilungsstörungen, Chirurgische Allgemeine Zeitschrift, 14 Jahrgang: 4 Heft, pp 1-4, 2013.

15. J. Dissemond, C. Dowsett, G Schultz T. Serena. EPA Made Easy, Wounds International, 4(1): 1-6, http://www.woundsinternational.com, May, 2013.

16. G. Schultz, R.R. Wolcott. Wound Infection and Diagnostics in Practice – What is Emerging? Wounds International, vol 4(1): 4-6, 2013.

17. J. Berlanga-Acosta, G.S. Schultz, E. López-Mola, G. Guillen-Nieto, M. García-Siverio, L. Herrera-Martínez. Glucose Toxic Effects on Granulation Tissue Productive Cells: The Diabetics’ Impaired Healing, BioMed Research International, Vol 2013, 15 pages, Article ID 256043, http://dx.doi.org/10.1155/2013/256043, 2013.

18. P. Phillips and G.S. Schultz. Molecular Mechanisms of Biofilm Infection: Biofilm Virulence Factors, Advances in Wound Care, 2(3): 109-114, 2012.

19. D.J. Leaper, G. Schultz, K. Carville, J. Fletcher, T. Swanson, R. Drake. Extending The TIME Concept: What Have We Learned In The Past 10 Years, International Wound J., 9 (suppl. 2) 1-19, 2012.

20. E. Pope, I. Lara-Corrales, J.E. Mellerio, A.E. Martinez, G. Schultz, R. Burrell, L. Goodman, P. Coutts, J. Wagner, U. Allen, M. Lee, J. Tolar, R.G. Sibbald. A Consensus Approach to Wound Care in Epidermolysis Bullosa, J Am Acad Dermatol, 67:904-917, 2012.

21. G. Schultz and C. Dowsett. Wound Bed Preparation Revisited, Wounds International, 3: 17-25, 2012. 22. L.G. Gutwein, M. Panigrahi, G.S. Schultz, B.A. Mast. Microbial Barriers, Clin Plastic Surg, 39(3), 229-238, 2012. 23. P.M. Robinson, T.D. Blalock, R. Yuan, A.S. Lewin, G.S. Schultz. Hammerhead ribozyme-mediated knockdown of

mRNA for fibrotic growth factors: transforming growth factor-beta 1 and connective tissue growth factor, Methods Mol Biol, 820: 117-132, 2012

24. L. Cowan, P. Phillips, B. Liesenfeld, A. Mikhaylova, D. Moore, J. Stechmiller, G. Schultz. Caution: When Combining Topical Wound Treatments, More Is Not Always Better, Wound Practice and Research, 19:60-64, 2011.

25. K. Harding, D. Armstrong, S. Barrett, H. Kaufma, J Lazaro-Martinez, D. Mayer, Z. Moore, M. Romanelli, D. Queen, G. Schultz, T. Serena, G. Sibbald, R. Snyder, R. Strohal, K. Vowden, P. Vowden, Wound Diagnostics And Proteases, An International Consensus Document, Wounds International, www.woundsinternational.com, 2011.

26. G.S. Schultz, J.M. Davidson, R.S. Kirsner, P. Bornstein, I.M. Herman. Dynamic Reciprocity in the Wound Microenvironment, Wound Repair Regen, 19:134-148, 2011.

27. P. Phillips, Q. Yang, D. Gibson, G. Schultz. Assessing the Bioburden in Poorly Healing Wounds, Wounds International, 2(2) 17-19, 2011.

28. P. Phillips, R. Wolcott, J. Fletcher, G. Schultz. Biofilms Made Easy, Wounds International, 1(3): 1-6, 2010. 29. J. Black, M. Baharestani, S. Black, J. Cavazos, T. Conner-Kerr, L. Edsberg, B. Peirce, E. G. Schultz. Recognition of

Tissue Types in Pressure Ulcers: A Consensus Panel Recommendation, Ostomy Wound Management, 56:28-44,

Page 12 of 38

2010. 30. G. Lloyd, G. Friedman, S. Jafri, G. Schultz, A. Fridman, K. Harding. Gas Plasma: Medical Uses and Developments

in Wound Care, Plasma Process Polymers, 7:194-211, 2010. 31. G. Schultz, J.B. Acosta, L. Cowan, J. Stechmiller. Linking the AGE/RAGE Pathway in Diabetics with Inflammation

and Topical Anti-Inflammatory Treatments of Chronic Wounds, Advances Wound Care, 1, 248-253, 2010. 32. P.L. Phillips, Q. Yang, E. Sampson, G. Schultz. Effects of Antimicrobial Agents on an In Vitro Biofilm Model of Skin

Wounds, Advances Wound Care, 1: 299-304, 2010. 33. D. Gibson, B. Cullen, R. Legerstee, K.G. Harding, G. Schultz. MMPs Made Easy, Wounds International,

November, 2009.G.S. Schultz, A. Wysocki. Interactions between extracellular matrix and growth factors in wound healing, Wound Repair Regen, 17:253-162, 2009.

34. D.J. Gibson, G. Schultz. Chronic Wound Diagnostic for Matrix Metalloproteinase, Wound Healing Southern Africa, 2(2):68-70, 2009.

35. P. Phillips, E. Sampson, Q. Yang, P. Antonelli, A. Progulske-Fox, G. Schultz. Bacterial Biofilms in Wounds, Wound Healing Southern Africa, 1(2):10-12, 2008.

36. J.B. Acosta, D.G. del Barco, D.C. Vera, W. Savigne, P. Lopez-Saura, G.G. Nieto, G.S. Schultz. The Pro-inflammatory Environment in Recalcitrant Diabetic Foot Wounds, International Wound J, 5:530-539, 2008.

37. A. Stojadinovic, J.W. Carlson, G.S. Schultz, T.A. Davis, E.A. Elster. Topical Advances in Wound Care, Gynecol Oncol, 111: supplement 2, S70-S80, 2008.

38. K. Harding, K. Becker, J. Boykin, M. Crossland, P. Davis, D. Doughty, V. Driver, C. von Eiff, C. Lindholm, M. Luubers, M. Millar, Z. Moore, S. Morbach, D. Queen, M. Romanelli, N. Santamaria, G. Schultz, G. Sibbald, M. Stacey, P. Vowden, H. Wallace. Diagnostics in Wound Management: A Consensus Document, International Wound Journal, 5: supplement, pp. 1-12, 2008.

39. K. Harding, K. Carville, J. Cuddigan, P. Fuchs, O. Ishikawa, D. Keast, D. Leaper, C. Lindholm, P. Moodley, E. Ricci, G. Schultz, J. Vasquez. Wound Infection in Clinical Practice, An International Consensus, International Wound Journal, 5: supplement, pp. 1-11, 2008.

40. S.S. Tuli, G.S. Schultz, D.M. Downer. Science and Strategy for Preventing and Managing Corneal Ulceration, The Ocular Surface, 5:23-39, 2007.

41. G. Schultz and J Stechmiller. Wound Healing and Nitric Oxide Production: Too Little or Too Much May Impair Healing and Cause Chronic Wounds, International J Lower Extremity Wounds, 5:6-8, 2006.

42. M. Granick, J. Boykin, R. Gamelli, G. Schultz, M. Tenenhaus. Toward a Common Language: Surgical Wound Bed Preparation and Debridement, Wound Repair Regen, 14:S1-S10, 2006.

43. G. Schultz. Règlement Biologique du Marquage (Biological Regulation of Scarring), Journal des Plaies et Cicatrisations, 54:83-88, 2006.

44. G. Schultz, D. Mozingo, M. Romanelli, K. Claxton. Wound Healing and TIME; New Concepts and Scientific Applications, Wound Repair Regen, 13 (sup 4):S1-S11, 2005.

45. R. Lobmann, G. S. Schultz, H. Lehnert. Proteases and the Diabetic Foot Syndrome – Mechanisms and Therapeutic Implications, Diabetes Care, 28:461-471, 2005.

46. G.S. Schultz, D. Barillo, D. Mozingo, G. Chin. Wound Bed Preparation and a Brief History of TIME, International Wound Journal, 1:19-32, 2004.

47. E.A. Ayello, C. Dowsett, G.S. Schultz, G. Sibbald, V. Falanga, K. Harding, M. Romanelli, M. Stacey, L. Teot, W. Vanscheidt. TIME to Prepare the Wound Bed: A New Approach to Chronic Wound Healing, Nursing 2004, 34:36-41, 2004.

48. G.A. Chin, G.S. Schultz, M. Stacey. Application of Wound Bed Preparation to Chronic Wound Treatments: TIME to Heal, Primary Intention, 11:171-187, 2003.

49. R.G. Sibbald, H. Orsted, G.S. Schultz, P. Coutts, D. Keats. Preparing The Wound Bed 2003: Focus On Infection and Inflammation, Ostomy Wound Manag, 49:23-51, 2003.

50. M. Lim, M.H. Goldstein, S.S. Tuli, G.S. Schultz. Growth Factor, Cytokine and Protease Interactions During Corneal Wound Healing, Ocular Surface, 1:53-65, 2003

51. G.S. Schultz, G. Sibbald, V. Falanga, E.A. Ayello, C. Dowsett, K. Harding, M. Romanelli, M. Stacey, L. Teot, W. Vanscheidt. Wound Bed Preparation, A Systemic Approach to Wound Bed Management, Wound Repair Regen, 11 (sup1):S1-S28, 2003.

52. R.G. Crystal, P.B. Bitterman, B. Mossman, M.I. Schwartz, L. Almasy, H.A. Chapman, S.L. Friedman, T.E. King, Jr., L.A. Leinwand, L. Liotta, G.R. Martin, D.A. Schwartz, G.S. Schultz, C.R. Wagner, R.A. Musson. Future Research Directions in Idiopathic Pulmonary Fibrosis: A Summary of a National Heart, Lung, and Blood Institute Working Group, Am J Resp Crit Care Med, 166:23-246, 2002.

53. G. Chin, S. Gowda, G. Schultz. Evaluation of Platelet-Derived Growth Factor in a Rat Model of Ischemic Skin Wound Healing, Wounds, 14:199-203, 2002.

54. T.D. Blalock, J.C. Varela, S. Gowda, Y. Tang, C. Chen, B.A. Mast, G.S. Schultz. Ischemic Skin Wound Healing Models in Rats, Wounds, 13:35-44, 2001.

55. B.A. Mast, G.S. Schultz. Growth Factors and Plastic Surgery, J Florida Medical Association, 86:87-91, 2000. 56. M.S. Ågren, W.H. Eaglstein, M.W.J. Ferguson, K.G. Harding, K. Moore, U.K. Saarialjo-Kere, G.S. Schultz. Causes

Page 13 of 38

and Effects of the Chronic Inflammation in Venous Leg Ulcers, Acta Derm Venereol, suppl 210:3-17, 2000. 57. M.F. Cordeiro, G.S. Schultz, R.R. Ali, S.S. Bhattacharya, P.T. Khaw. Molecular Therapy in Ocular Wound Healing,

Br J Ophthalmol, 83:1219-1224, 1999. 58. G.S. Schultz, B.A. Mast. Molecular Analysis of the Environment of Healing and Chronic Wounds: Cytokines,

Proteases and Growth Factors, Primary Intention, 7:7-14, 1999. 59. G.S. Schultz, B.A. Mast. Molecular Analysis of the Environment of Healing and Chronic Wounds: Cytokines,

Proteases and Growth Factors, Wounds: A Compendium of Clinical Research and Practice, vol 10, Supplement F, 1F-10F, 1998.

60. B.A. Mast, G.S. Schultz. Interactions of Cytokines, Growth Factors, and Proteases in Acute and Chronic Wounds, Wound Repair Regen, 4:411-420, 1996.

61. R.W. Tarnuzzer, G.S. Schultz. Biochemical Analysis of Acute and Chronic Wound Environments, Wound Repair Regen, 4:321-325, 1996.

62. P.T. Khaw, N.L. Occleston, G. Schultz, I. Grierson, M.B. Sherwood, G. Larkin. Activation and Suppression of Fibroblast Function, Eye, 8:188-195, 1994.

63. G.B. van Setten, G.S. Schultz, S.P. Macauley. Growth Factors in Human Tear Fluid and Lacrimal Glands, Adv Exp Med Biol, 350:315-319, 1994.

64. G.S. Schultz, P.T. Khaw, K.W. Oxford, S.P. Macauley, G.B. van Setten, N. Chegini. Growth Factors and Ocular Wound Healing, Eye, 8:184-187, 1994.

65. N.T. Bennett, G.S. Schultz. Growth Factors and Wound Healing: Part II. Role in Normal and Chronic Wound Healing, Am J Surgery, 166:74-81, 1993.

66. N.T. Bennett, G.S. Schultz. Growth factors and Wound Healing: Part I. Biochemical Properties of Growth Factors and Their Receptors, Am J Surgery, 165:728-737, 1993.

67. G.S. Schultz, N. Chegini, M. Grant, P.T. Khaw, S.L.D. MacKay. Effect of Growth Factors On Corneal Wound Healing, Acta Ophthalmologica, 70:60-66, 1992.

68. G.S. Schultz, M.B. Grant. Neovascular Growth Factors, Eye, 5:170-180, 1991.

69. G.S. Schultz, D.S. Rotatori, W. Clark. EGF and TGF- in Wound Healing and Repair, J Cell Biochem, 45: 346-352, 1991.

70. G.S. Schultz, J.B. Davis, R.A. Eiferman. Growth Factors and Corneal Epithelium, Cornea, 7:96-101, 1988.

Book Chapters 1. G.S. Schultz and D.J. Gibson. Physiology and Biochemistry of Wound Healing, Chapter 2. In: Textbook of Clinical

Wound Medicine, C Fife editor, Best Publishing Co., Noth Palm Beach, Florida, USA, in press. 2. S. Holloway, K. Harding, J Stechmiller, G. Schultz. Acute and Chronic Wound Healing. In: Wound Care

Essentials: Practice Principles, S. Baranoski, and E.A. Ayello, eds., 4th edition, Lippincott Williams & Wilkins, Springhouse, PA, Chapter 5, in press.

3. G. Schultz and G. Patel. Biological Approaches to Wound Healing, Chapter 14, in ABCs of Wound Healing, eds, K. Harding and G. Patel, British Medical Journal Series, London, UK, in press.

4. J. Berlanga-Acosta, G.S. Schultz, P Lopez-Saura. Biology of the Diabetic Wound. In: Foot Ulcers: Causes, Diagnosis and Treatments, P.E. Overhaussen, editor. Nova Science Publishers, Inc., Hauppauge, NY, USA, in press.

5. P. Phillips, R. Wolcott, L. Cowan, G. Schultz. Biofilms in Wounds and Wound Dressings, Chapter 3, pp. 55-78, in Wound Healing Biomaterials Vol 2, ed Magnus Agren, 2016.

6. G. Schultz, P. Phillips, D. Gibson. Molecular and Cellular Regulators. In: Acute and Chronic Wounds: Current Management Concepts, 5th edition, R.A. Bryant & D.P. Nix, eds., Mosby Inc., St. Louis, MO, Chapter 20, pp. 324-336, 2015

7. P.M. Robinson, S.S. Kim, S. Sriram, S.Tuli, W.W. Hauswirth, A.S. Lewin, G.S. Schultz. Reduction of Profibrotic Connective Tissue Growth Factor in Wounded Rat Corneas using a Ribozyme Expressed in Self Complimentary Adeno-Associated Virus. In: Wound Healing: Cellular Mechanisms, Alternative Therapies and Clinical Outcomes, L. E. Wade, editor, Nova Science Publisher, Inc., Hauppauge, NY, Chapter 2, pp. 25-42, 2015.

8. S.S. Tuli, M. B. Sherwood, G.S. Schultz. Biological Drivers of Postoperative Scarring. In: Glaucoma, 2nd edition, T. Shaarawy, M.B. Sherwood, R. Hitchings, J.G. Crowston, eds. Elsevier, London, UK, Chapter 94, pp.924-931, 2015.

9. L. Cowan, J. Stechmiller, P. Phillips, G. Schultz. Science of Wound Healing: Translation of Bench Science into Advances for Chronic Wound Care. In: Chronic Wound Care: The Essentials, D. L. Krasner, editor, HMP Communications, Malvern, PA, Chapter 3, pp 17-27, 2014.

10. L. Cowan, P. Phillips, J. Stechmiller, Q. Yang, R. Wolcott, G. Schultz, Antibiofilm Strategies and Antiseptics, in

Antiseptics in Surgery Update 2013, edited by Christian Willy, Lundqvist Books, Berlin, Germany, Chapter 4, pp.

23-30, 2013. 11. B.M. Bates-Jensen, G. Schultz, L.G. Ovington, K. Rush. Management Of Exudate, Biofilms, And Infection. In:

Wound Care: A Collaborative Practice Manual for Health Professionals, C. Sussan and B.M. Bates-Jensen,

Page 14 of 38

editors, 4th edition, Lippincott Williams & Wilkins, Hagerstown, MD, Chapter 18, pp. 457-476, 2012. 12. G.S. Schultz and D.J. Gibson. Measurement of Biomarkers for Impaired Healing in Fluids and Tissues. In:

Measurements in Wound Healing: Science and Management, R. Mani, M. Romanelli, and V. Shukla eds, Springer Publishing Co, New York, NY, Chapter 23, pp. 243-258, 2012.

13. G. Schultz. The Physiology of Wound Bed Preparation. In: Surgical Wound Healing and Management, 2nd ed., M. Granick and Luc Teot, eds., CRC Press, Informa Health Care, New York, NY, Chapter 1, pp. 1-17, 2012.

14. L. Cowan, J. Stechmiller, P. Phillips, G. Schultz. Science of Wound Healing. In: Chronic Wound Care: A Clinical Source Book for Healthcare Professionals, 5th edition, volume 1, D. L. Krasner, G. T. Rodeheaver, R. G. Sibbald, and K. Y. Woo, eds., HMP Communications, Malvern, PA, Chapter 1.3, pp 25-35, 2012.

15. G.S. Schultz, G.A. Chin, L.L. Moldawer, R.F. Diegelmann. Principles of Wound Healing. In: Mechanisms of Vascular Disease: A Textbook for Vascular Surgeons, M. Thompson, R Fitridge, eds., 2nd edition, Greenwich Medical Media Ltd, London UK, Chapter 23, 423-449, 2011.

16. S. Holloway, K. Harding, J Stechmiller, G. Schultz. Acute and Chronic Wound Healing. In: Wound Care Essentials: Practice Principles, S. Baranoski, and E.A. Ayello, eds., 3rd edition, Lippincott Williams & Wilkins, Springhouse, PA, Chapter 5, pp. 83-100, 2011.

17. G. Schultz. Molecular and Cellular Regulators. In: Acute and Chronic Wounds: Current Management Concepts, 4rd edition, R.A. Bryant & D.P. Nix, eds., Mosby Inc., St. Louis, MO, Chapter 20, pp. 324-336, 2011.

18. S.S. Tuli, D.W. Esson, M. B. Sherwood, G.S. Schultz. Biological Drivers of Postoperative Scarring. In: Glaucoma, T. Shaarawy, M.B. Sherwood, R. Hitchings, J.G. Crowston, eds. Elsevier, London, UK, Chapter 113, pp 557-564, 2009.

19. G.S. Schultz, E.A. Ayello, H. Brem. Wound Debridement. In: Essential Tissue Healing of the Face and Neck, D.A. Hom, P.A. Hebda, A.K. Gosain, C.D. Friedman, eds., B.C. Decker, Inc., Hamilton, Ontario, Canada, Chapter 26, pp. 349-366, 2009.

20. G.S. Schultz. Molecular Regulation of Wound Healing. In: Acute and Chronic Wounds: Current Management Concepts, 3rd edition, R.A. Bryant & D.P. Dix, eds., Mosby Inc., St. Louis, MO, Chapter 5, pp 82-99, 2007.

21. V. Jones, S. Bale, K. Harding, J Stechmiller, G. Schultz. Acute and Chronic Wound Healing. In: Wound Care Essentials: Practice Principles, S. Baranoski, and E.A. Ayello, eds., 2nd edition, Lippincott Williams & Wilkins, Springhouse, PA, Chapter 5, pp. 64-76, 2007.

22. G.A. Chin, G.S. Schultz, R.F. Diegelmann, N. Chegini. Biochemistry of Wound Healing. In: Wound Care Practice, Paul Sheffield, ed., 2nd edition, Best Publishing Co., Flagstaff, AZ, USA, Chapter 2, pp. 51-78, 2007.

23. J. Stechmiller, G. Schultz,. Bench Science Advances for Chronic Wound Care. In: Chronic Wound Care: A Clinical Source Book for Healthcare Professionals, D. L. Krasner, G. T. Rodeheaver, and R. G. Sibbald, eds., 4th edition, HMP Communications, Malvern, PA, Chapter 8, pp. 67-73, 2007.

24. G. Schultz. The Physiology of Wound Bed Preparation. In: Surgical Wound Healing, M. Granick and G. Gamelli, eds., Informa Healthcare, New York, NY, Chapter 1, pp.1-16, 2007.

25. G.S. Schultz, G.A. Chin, L.L. Moldawer, R.F. Diegelmann. Principles of Wound Healing. In: Mechanisms of Vascular Disease: A Textbook for Vascular Surgeons, M. Thompson, R Fitridge, eds., Greenwich Medical Media Ltd, London UK, Chapter 23, pp. 329-345, 2007.

26. G.A. Chin, R.F. Diegelmann, G.S. Schultz. Cellular and Molecular Regulation of Wound Healing. In: Wound Healing: Science and Practice, A. Falabella, and R.S. Kirsner, eds., Marcel Dekker, Inc. New York, NY, USA, Chapter 3, pp 17-38, 2005.

27. Wysocki, T. Mustoe, G. Schultz. Molecular Cell Biology of Skin. In: Encyclopedia of Molecular Cell Biology and Molecular Medicine, Wiley-VCH Verlag, Weinheim, Germany, Vol 13, pp. 217-250, 2005.

28. S.S. Tuli, M.H. Goldstein, G.S. Schultz. Modulation of Corneal Wound Healing. In: Cornea, 2nd edition, J.H. Krachmer, M. J. Mannis and E. J. Holland, eds., Mosby-Year Book, Philadelphia, PA. Chapter 9, pp.133-150, 2005.

29. G.A. Chin, G.S. Schultz, N. Chegini, R.F. Diegelmann. Biochemistry of Wound Healing. In: Wound Care Practice, Paul Sheffield, ed., Best Publishing Co., Flagstaff, AZ, USA, pp. 49-71, 2004.

30. L. Ovington, G.S. Schultz. Physiology of Wound Healing. In: Chronic Wound Care: A Problem-Based Learning Approach, M. Morison, L. Ovington, and K. Wilkie, eds., Harcourt Health Sciences, London, UK, pp. 83-100, 2004.

31. G.A. Chin, L.L. Moldawer G.S. Schultz. Growth Factors, Cytokines and Chemokines. In: Basic Science for Surgical Specialists, L.C. Argenta, ed., W. B. Sanders Co., Philadelphia, PA, pp. 25-42, 2004.

32. P.J. Antonelli, G.S. Schultz, D.J. Sundin, P.A. Pemberton PA. Inhibition of Proteases with Alpha 1-Antitrypsin and Ilomastat in Human Otitis Media. In: Eighth International Symposium on Recent Advances in Otitis Media. M. Casselbrant and D. Lim, eds., B.C. Decker, Hamilton ON, Canada, 2004.

33. H.N. Paddock, G.S. Schultz, B.A. Mast. Methods in Re-Epithelialization: A Porcine Model of Partial Thickness Wounds. In: Wound Healing: Methods and Protocols, Methods of Molecular Medicine, J.M. Walter, ed., Humana Press, Totowa, NJ, pp. 17-36, 2003.

34. G.S. Schultz. Molecular Regulation of Wound Healing. In: Acute and Chronic Wounds: Nursing Management, 2nd edition, R. Bryant ed., Mosby Inc., St. Louis, MO, pp.413-454, 2000.

35. W.C. Parks, G.S. Schultz. Proteases and Protease Inhibitors in Tissue Repair. In: Peritoneal Surgery, G. di

Page 15 of 38

Zerega, ed., Springer-Verlag, New York, NY, Chapter 7, pp. 101-113, 2000. 36. N.C. Kerr, G.S. Schultz, R.E. Eiferman. Endothelium: Development, Morphology, Disease and Repair. In: Corneal

Surgery: Theory, Technique, and Tissue, 3rd edition, F.S. Brightwell, ed., Mosby Inc., St. Louis, MO, Chapter 7, pp. 60-72, 1999.

37. G.S. Schultz. Future Developments in Corneal Therapy: Growth Factors. In: Textbook for Ocular Pharmacology, T Zimmerman and K Kooner, eds., Raven Press, New York, NY, Chapter 58, pp. 675-679, 1997.

38. G. Rocha, G.S. Schultz. Corneal Wound Healing in Laser In situ Keratomileusis. In: Advances in Refractive and Corneal Surgery, M.D. Duplessie, G. Rocha, and J.C. Sanchez-Thorin, eds., Little, Brown and Co., Boston, MA, vol 36, pp. 9-20, 1996.

39. G.S. Schultz. Comparative Tissue Repair. In: Proceeding of the 3rd International Congress on Pelvic Surgery and Adhesion Formation, G.S. diZerega, ed., Springer Verlag, New York, NY. Chapter 3, pp. 26-36, 1997.

40. R.W. Tarnuzzer, S.M. Macauley, B.A. Mast, M.C. Stacey, N. Trengove, J. Gibson, L.L. Moldawer, F. Burslem, G.S. Schultz. Epidermal Growth Factor: A Model for the Molecular Pathogenesis of Chronic Wounds. In: Growth Factors and Wound Healing: Basic Science and Potential Clinical Applications, T.R. Ziegler, G.F. Pierce, and D.N. Herndon, eds., Serono Symposium Inc., Norwell, MA, Chapter 12, pp. 206-228, 1997.

41. G.S. Schultz. Modulation of Corneal Wound Healing. In: Cornea J.H. Krachmer, M. J. Mannis and E. J. Holland, eds., Mosby-Year Book, Philadelphia, PA. Chapter 9, 183-198, 1996.

42. G.S. Stern, G.S. Schultz. Pathogenesis of Bacterial Infections of the External Eye. In: Duane’s Foundations of Clinical Ophthalmology, W. Tasman and E. A. Jaeger, eds., pp. 1-11, 1996.

43. M.B. Sherwood, K. Kato, J.W. Doyle, J.T. Garcia, P.T. Khaw, G.S. Schultz, S. McGorray. Tissue Effects of External Topical Mitomycin-C in Rabbits and its Application to Low Dose Mitomycin-C Therapy. In: Glaucoma Update, G.K. Kreiglstein, ed., Verlag Springer, Berlin, Germany. 5:364-371, 1995.

44. R.E. Galardy, M.E. Cassabonne, C. Giese, J.H. Gilbert, F. Lapierre, H. Lopez, M.E. Schaefer, R. Stack, M. Sullivan, R. Summers, R. Tressler, D. Terrell, J. Wee, S.D. Allen, J.J. Castellot, J.P. Barletta, G.S. Schultz, L.A. Fernandez, S. Fisher, T-Y. Cui, H.G. Foellmer, D. Grabelny, W.M. Holleran. Low Molecular Weight Inhibitors of Corneal Ulceration. In: Inhibition of Matrix Metalloproteinases: Therapeutic Potential, R.A. Greenwald and L.M. Golub eds., New York Academy of Sciences vol 732, pp. 315-323, 1994.

45. N.C. Kerr, G.S. Schultz, R.E. Eiferman. Endothelium: Development, Morphology, Disease and Repair. In: Corneal Surgery: Theory, Technique, and Tissue, 2nd edition, F.S. Brightwell, ed., Mosby Co. St. Louis, MO, pp.52-62, 1993.

46. G.S. Schultz, N.T. Bennett. Growth Factors: Biochemical Characteristics and Roles in Wound Healing. In: Cytokines and Critical Illness, A.F. Roach, ed., Report of the 11th Ross Conference on Medical Research, Ross Laboratories, Columbus, OH, pp. 8-13, 1992.

47. S.L.D. MacKay, N.T. Bennett, K.I. Bland, G.S. Schultz. Growth Factors Tumor Suppressor and Cancer. In: Perspectives in General Surgery, B.A. Levine, ed. 3:1-25, 1992.

48. G.S. Schultz, D. Twardzik. Assessment Of Biological Activity Of Synthetic Fragments Of Transforming Growth

Factor . In: Methods in Enzymology, D Barns, J P Mather, and G H Sato, editors, Academic Press, Inc., New York NY, Vol 198, pp. 200-213, 1991

49. G.S. Schultz. Epidermal growth factor in wound healing. In: Biological Response Modifiers for Ophthalmic Tissue Repair, G.R. Grotendorst, L.M. Hjelmeland, and J.P. Gills, editors. Gulf Publishing Co., Houston, TX, pp. 171-182, 1990

50. G. Todaro, G.S. Schultz, D.R. Twardzik, R.A. Eiferman. Tumor Growth Factors and Vaccinia Growth Factors: Role in Epithelial Wound Healing. In: Development and Disease of Cartilage and Bone Matrix. Alan R. Liss, Inc., New York, p. 612, 1987.

51. R.A. Eiferman, G.S. Schultz, R.E. Nordquist. Corneal Wound Healing and its Pharmacologic Modification after Refractive Keratotomy. In: Refractive Keratotomy for Myopia and Astigmatism, G. O Waring, III ed., C.V. Mosby Co., St. Louis, pp. 749-779, 1991.

52. G.S. Schultz, P.W. Woost, R.A. Eiferman. Modification of Corneal Wound Healing by Growth Factors. In: The Cornea: Transforming of the World Congress on the Cornea III, D. Cavanaugh, ed., Raven Press, New York, NY, pp.15-21, 1988.

53. G.S. Schultz, R.A. Eiferman. Human Corneal Endothelial Mitosis and Endothelial Grafting. In: Corneal Surgery, F. Brightbill, ed., C.V. Mosby Co., St. Louis, pp. 613-620, 1986.

Other Publications 1. T. Bjarnsholt, G. Schultz, K. Kirketerp-Mᴓller, J. Fletcher M. Malone. The Role of Biofilms in Delayed Wound Healing,

in Management of Biofilm, World Union of Wound Healing Societies Position Document, Wounds International, 4-9, 2016.

Page 16 of 38

2. G. Schultz, T. Bjarnsholt, R. Cooper, K. Kirketerp-Mᴓller, R. Cooper. Biofilm Research: Filling in the Gaps in Knowledge in Chronic Wounds, in Management of Biofilm, World Union of Wound Healing Societies Position Document, Wounds International, 17-25, 2016.

3. S. Carpenter, S. Davis, F. Fitzgerald, M. Gehling, D. Kapp, J. Karr, J. Samies, G. Schultz, A. Teichman, D. Weir. Expert Recommendations for Optimizing Outcomes in the Management of Biofilm to Promote Healing of Chronic Wounds in the Veterans Health Administration System, Wounds, supplement June 2016.

4. T. Swanson, D. Keast, R. Cooper, J. Black, D. Angel, G. Schultz, K. Carville, J. Fletcher. Ten Top Tips: Identification Of Wound Infection in a Chronic Wound, Wounds International, 6(2):22-27, 2015.

5. D. Keast, T. Swanson, K. Carville, J. Fletcher, G. Schultz, J. Black. Ten Top Tips: Understanding and Managing Wound Biofilm, Wounds International, 5(2):20-24, 2014.

6. G. Sussman, T. Swanson, J. Black, R. Cooper, J. Fletcher, G.S. Schultz, D. Smith. Ten Top Tips: Reducing Antibiotic Resistance, Wounds International, 5(4): 4-8, 2014.

7. D. Weir and G.S. Schultz. Assessment and Management Wound-Related Infections. Chapter 10, in Wound, Ostomy and Continence Nurses Society Core Curriculum, 2014.

8. J. Berlanga-Acosta, D.G. Armstrong, G.S. Schultz, and L. Herrera-Martinez. Chronic Wounds with Emphasis in Diabetic Foot Ulcers. BioMed Res Communications, Volume 2014, Article ID 890352, <http://dx.doi.org/10.1155/2014/890352>.

9. G. Schultz. Discussion: Biomarkers to Predict Wound Healing: The Future of Complex War Wound Management. Plast Reconst Surgery, 127(1S): 27S, 2011.

10. J. Cuddigan et al. Pressure Ulcer Prevention and Treatment Guidelines, National Pressure Ulcer Advisory Panel, 2010.

11. J. Azeke, D.J. Gibson, P. Phillips, G. Schultz. A Primer For Proteases And Wound Dressings. Canadian Nursing, 2010.

12. G. Schultz. Research to Improve Wound Management, Guest Editorial. Wound Practice and Research 16:108, 2008.

13. G.S. Schultz, The Role of Oxygen in Wound Healing. Position Paper of European Committee on Hyperbaric Medicine, 2008.

Online Webinars 1. Gregory Schultz, Biourden – Biofilms and Inflammation, AMA PRA category 1 credit , WebCME,

https://app.frame.io/f/TV4kwf7H, April 27, 2017. 2. Gregory Schultz, Battling Biofilms: How to Win the War in Wounds, Southeast Region of Wound Ostomy and

Continence Nurses Society, http://www.serwocn.org/eLearn_biofilms/index.html, December, 2016. 3. Gregory Schultz, Battling Biofilms in Pressure Injuries, National Pressure Ulcer Advisory Panel, webinar online at

http://www.npuap.org/resources/educational-and-clinical-resources/complimentary-educational-webinars/, November 17, 2016.

4. Gregory Schultz, Thomas Bjarnsholt, Randy Wolcott. Understanding Biofilms, Smith & Nephew webinar online at http://view6.workcast.net/?cpak=7492979862614101&pak=6571675589438474, November 30, 2016

5. Gregory Schultz and Dot Weir. Breaking Down the Barriers to Wound Healing: Selective Debridement for Effective Wound Bed Preparation. North American Center for Continuing Medical Education, webinar online at http://www.naccme.com/program/2015-631-6, January 15, 2016.

6. Gregory Schultz and Matthew Regulski. Chronic Wounds: Cellular Biology and Management, North American Center for Continuing Medical Education, webinar online at http://www.woundcme.org/program/2014-627 January 1, 2015.

7. Gregory Schultz. Molecular and Cellular Regulation of Normal Skin Wound Healing – What Goes Wrong When Wounds Fail to Heal or Heal Too Much? Henry Stewart Talks webinar series on Wound Healing, webinar online at <http://hstalks.com/main/view_talk.php?t=2919&r=806&j=756&c=252, October, 2014.

8. Gregory Schultz. Biofilms and Chronic Wounds: Winning the War in Wounds. Henry Stewart Talks webinar series on Wound Healing, webinar online at http://hstalks.com/main/view_talk.php?t=2922&r=806&j=756&c=252, October, 2014

9. Gregory Schultz and John Lantis. The Biofilm Challenge; Get It Right From the Start. Webinar online at https://attendee.gotowebinar.com/register/3002426869326689282, August 26, 2014.

10. Gregory Schultz and Christine Wea. Biofilms: Is Your Strategy Working? Webinar online at http://www.woundcarejobs.com/education/clinical-webcasts/biofilms-is-your-strategy-working, March 25, 2014.

11. Gregory Schultz and J. Lantis. Cracking the Biofilm Armor. Webinar online at <http://www.woundcarejobs.com/education/clinical-webcasts/cracking-the-biofilm-armor>, June 2013.

12. Gregory Schultz and Tom Serena. Innovative Strategies for Healing Venous Leg Ulcers: Clinical Applications of Dehydrated Amniotic Membranes. Webinar online at http://www.naccme.com/program/2012-455-3. CME, CNE, CPME accredited, by North American Center for Continuing Medical Education (NACCME) on line, June 2012.

13. Gregory Schultz and John Lantis. Understanding Biofilm-Based Wound Care: What You Need To Know. Webinar

Page 17 of 38

online at http://www.woundsinternational.com/webcasts/understanding-biofilm-based-wound-care-what-you-need-to-know, January 2012.

14. William Marston and Gregory Schultz. Chronic Wounds: Roles of MMPs, ROS, and Bacteria on Inflammation. CME, CNE, CPME accredited by North American Center for Continuing Medical Education (NACCME), Webinar online at http://naccme.com/sawc/program/2011-443-1; August 2011.

15. Valerie Edwards-Jones, Gregory Schultz, and John Douglass. The Significance of Biofilms in Wound Infections. Webinar online at http://www.woundinfection-institute.com/update/283001/biofilms.html, August 2011.

16. Gregory Schultz, Glenn Ladwig, and Annette Wysocki. Extracellular Matrix: Review of Its Roles in Acute and Chronic Wounds. Webinar online at http://www.worldwidewounds.com/2005/august/Schultz/Extrace-Matric-Acute-Chronic-Wounds.html, August, 2005.

Submitted Publications 1. M. Gore, Y. Dound, S. Jadhav, G. Schultz, B. Liesenfeld, D. Mehta. Evaluation of Safety and Efficacy of Microfoam

Barrier Foam Dressings in Patients with Exudating Wounds. International Wound Journal, Jan 2017. 2. Q. Yang, D. Porta, G. Schultz, D. Gibson. The Mechanism of Action of an Anti-Biofilm Surfactant-Based Dressing,

submitted to Wound Repair Regeneration, Dec 2016. 3. D. Weinstein, S. Saikaly, J. Allickson, D. Wang, R. Snyder, G. Schultz. A Pre-clinical Study for Improvement of

Chronic Wound Healing Utilizing a Biodegradable Scaffold as Support for Mesenchymal Human Stem Cells Derived from Menstrual Blood (MenSCs). Submitted to International Wound Journal, Jan 2016.

4. N. Vedrenne, N. Lamri-Zeggar, N. Bordeau, C. Vitrac, S. Rodriguez, V. Sarrazy, G.S. Schultz, A. Desmoulière, F.

Billet. TGF-1 Antisense Oligonucleotide Reduces Behavioral Impairments In Rats. Submitted to Exp Neurol, 2015.

Patents Awarded 1. Promotion of Corneal Stroma Wound Healing With Human Epidermal Growth Factor Prepared From Recombinant

DNA. Inventors: G.S. Schultz, R.A. Eiferman, G.L. Brown, assigned to University of Louisville, and P. Valenzuela, assigned to Chiron Corporation, U.S. Patent No. 4,959,353, issued September 25, 1990.

2. Treatment for Tissue Ulceration. Inventors: R.E. Galardy, D. Grobelny, G.S. Schultz assigned to University of Florida. U.S. Patent No. 5,114,953, issued May 19, 1992.

3. Treatment for Tissue Ulceration. Inventors: R.E. Galardy, D. Grobelny, G.S. Schultz assigned to University of Florida. U.S. Patent No. 5,270,326, issued December 14, 1993.

4. Method for Treating Corneal Endothelial Wounds. Inventors: G.S. Schultz assigned to University of Florida and R.W. Shimuzu assigned to Chiron Vision. U.S. Patent No. 5,310,728, issued May 10, 1994.

5. Synthetic Matrix Metalloproteinase Inhibitors and Use Thereof. Inventors: R.E. Galardy, D. Grobelny, G. Schultz assigned to University of Florida. U.S. Patent No. 5,773,438, issued June 30, 1998.

6. Process for Preparing Synthetic Matrix Metalloprotease Inhibitors. Inventors D.E. Levi, D. Grobelny, C. Tang, K.R. Holme, R.E. Galardy, A. Nematalia, J.H. Musser, all assigned to Glycomed, and G. Schultz, assigned to the University of Florida. U.S. Patent No. 5,892,112; issued April 6, 1999.

7. Medical Use of Metalloproteinase Inhibitors for Inhibiting Tissue Contraction. Inventors: P.T. Khaw, assigned to University of London, and G.S. Schultz assigned to University of Florida. U.S. Patent No. 6,093,398 issued July 25, 2000.

8. Medical Use of Metalloproteinase Inhibitors for Inhibiting Tissue Contraction. Inventors: P.T. Khaw, assigned to University of London, and G.S. Schultz assigned to University of Florida. U.S. Patent No. 6,379,667 issued April 30, 2002.

9. Cosmetic Composition and Method. Inventors: G.S. Schultz, assigned to University of Florida, and D.S. Lerner, assigned to QuickMed Technologies. US Patent No. 6,713,074, issued March 30, 2004.

10. Intrinsically Bactericidal Absorbent Dressing and Method of Fabrication. Inventors: C.D. Batich, G.S. Schultz, B.A. Mast, assigned to University of Florida, G.M. Olderman, D.S. Lerner, assigned to QuickMed Technologies. Australian patent No. 773532, issued September 9, 2004, 2004. Eurasian Patent No. 004160, issued February 26, 2004.

11. Medical Use of Metalloproteinase Inhibitors for Inhibiting Tissue Contraction. Inventors: P.T. Khaw, assigned to University of London, and G.S. Schultz assigned to University of Florida. U.S. Patent No. 6,759,432 B2, issued July 6, 2004.

12. Cosmetic Composition and Method. Inventors: G.S. Schultz, assigned to University of Florida, and D.S. Lerner, assigned to QuickMed Technologies. Australian Patent No. 2,001,273,115, issued June 3, 2005.

13. Intrinsically Bactericidal Absorbent Dressing and Method of Fabrication. Inventors: C.D. Batich, B.A. Mast, G.S. Schultz, assigned to University of Florida, and G.M. Olderman, D.S. Lerner, assigned to QuickMed Technologies. U.S. Patent 7,045,673 B1, issued May 16, 2006.

14. Herpes Virus Ribozymes and Vectors. Inventors: G.S. Schultz, A.S. Lewin, D. Bloom, S. Tuli, J. Liu, assigned to University of Florida, U. S. Patent No. 7,335,763, issued February 26, 2008.

15. Anti-Scarring Ribozymes and Methods. Inventors: G.S. Schultz, A.S. Lewin, T.D. Blalock, assigned to University of Florida, U. S. Patent No. 7,462,602, issued December 9, 2008.

Page 18 of 38

16. Absorbent Materials with Covalently Bonded, Nonleachable, Polymeric, Antimicrobial Surfaces, and Methods for Preparation. C.D. Batich, G. Schultz, B.A. Mast, assigned to the University of Florida, and G.M. Olderman, D.S. Lerner, and W. Toreki assigned to QuickMed Technologies. U.S. Patent No. 7,709,694, issued May 4, 2010.

17. Herpes Virus Ribozymes and Vectors Continuation in Part I. Inventors: G.S. Schultz, A.S. Lewin, D. Bloom, S. Tuli, J. Liu. Assigned to University of Florida, U. S. Patent No. 7,838,659, issued November 23, 2010.

18. Novel Devices for Detection of the Presence and/or Activity of Proteases in Biological Samples. Inventors: G Schultz, C Batich, J Azeke, W Tan, D Gibson, O Moloye, P Phillips. Assigned to the University of Florida. U.S. Patent No. 8,058,024, issued November 15, 2011.

19. Cosmetic Composition and Method Comprising a Hydroxamate MMPI and a Triterpenoid Glycoside. Inventors: Inventors: G.S. Schultz, assigned to University of Florida, and D.S. Lerner, assigned to QuickMed Technologies. Canadian Patent #CA 2414,247, issued March 16, 2012.

20. Antimicrobial Bandage Material Comprising Superabsorbent and Non-Superabsorbent Layers. Inventors: Gregory S. Schultz, William Toreki, Gerald M. Olderman, Christopher D. Batich. Assigned to the University of Florida. U.S. Patent No. 8,333,743, issued December 18, 2012.

21. Cosmetic Composition and Method. Inventors: G.S. Schultz, assigned to University of Florida, and D.S. Lerner, assigned to QuickMed Technologies. Japanese Patent No. 2002-524467, issued October 11, 2012.

22. Novel Devices For The Detection Of The Presence And/Or Activity Or Proteases In Biological Samples. Inventors: G Schultz, J Azeke, D Gibson, P Phillips, W Tan, C Batich. Assigned to the University of Florida. U.S. Patent No. 8,551,764 B2, issued on October 8, 2013.

23. Method and Device for Electromotive Delivery of Macromolecules into Tissue. Inventors: D. Gibson, G Schultz, S. S. Tuli. Assigned to the University of Florida. US Patent No. 8,838,229, issued on September 16, 2014.

24. Materials and Methods for Measuring Nitric Oxide Levels in Biological Fluids. Inventors: G. Schultz, D.J. Gibson. Assigned to University of Florida. U.S. Patent No. 8,906,693, issued on December 9, 2014.

25. Novel Devices For The Detection Of The Presence And/Or Activity Of Proteases In Biological Samples. Weihong Tan, John I. Azeke, Priscilla Lorraine Phillips, Olajompo B. Moloye, Christopher D. Batich, Gregory S. Schultz, Daniel J. Gibson. Assigned to the University of Florida. Australian Patent No. 2008341105, issued May 28, 2015.

26. Materials and Methods for Assessing and Mapping Microbes and Microbial Biofilms on Wounds. Inventors: P. Phillips, E. Sampson, G.S. Schultz. Assigned to the University of Florida. US Patent No. 9,145,574, issued on September 29, 2015.

27. Cosmetic Composition and Method. Inventors: G.S. Schultz, assigned to University of Florida, and D.S. Lerner, assigned to QuickMed Technologies. European Patent Office No. 01 952 355.4, issued January 8, 2016.

28. Rapid Bed-Side Measurement of Neutrophil Elastase Activity in Biological Fluids. Inventors: G. Schultz, D. Gibson. Assigned to the University of Florida. Australian Patent No. 2010026548; issued May 12, 2016.

29. Novel Devices For The Detection Of The Presence And/Or Activity Or Proteases In Biological Samples. Inventors: G. Schultz, J. Azeke, D. Gibson, P. Phillips, W. Tan, C. Batich. Assigned to the University of Florida. Canadian Patent No. 2,743,178, issued on March 21, 2017.

Patent Applications Filed 1. Method For Delivering RNA To Neurons To Treat Herpes Infections. Inventors: David C. Bloom, Alfred S. Lewin,

Donna M. Neumann, Zachary L. Watson, Sonal Sanjeev Tuli, Gregory Scott Schultz. U.S. Provisional Application No.: 62/353,019, filed 06/21/2016.

2. Concealed Laparoscopic Pelvic Mass Removal Device. Inventors: Erich T Wyckoff, Daniel J. Gibson, Christopher D. Batich, Gregory Scott Schultz. U.S. Provisional App. No. 62/192,388, Filing date: July 14, 2016.

3. Compositions, Systems, and Methods for Scar Tissue Modification. Inventors: Mark B. Sherwood, Daniel J. Gibson, Gregory Scott Schultz. U.S. Provisional Patent Application No. 62/323,921, Filing Date: April 18, 2016.

4. Bilayered Devices For Enhanced Healing. Inventors: Anthony B. Brennan, Bradley Jay Willenberg, Gregory Scott Schultz, Dylan Neale; US Provisional Patent Application 62/151,875, Filing date: April 5, 2016; International Application Number PCT/US16/29122US, Filing date: April 25, 2016.

5. Surface-Plasmon Array System and Method of Generating a Filtered Surface Plasmon Resonance Signal. Inventors: Mark Roger Davidson, Peng Jiang, Pei-Yu Chung, Christopher D. Batich, Gregory S. Schultz. PCT/US2012/61/635,331, Filing date: April 19, 2012.

6. Materials and Methods for Efficient and Accurate Detection of Analytes. Inventors: G Schultz, C Batich, J Azeke, W Tan, D Gibson, O Moloye, P Phillips. PCTUS2010/512515, Filing date: April 20, 2010.

7. Rapid Bed-Side Measurement of Neutrophil Elastase Activity in Biological Fluids. Inventors: G Schultz, D Gibson. PCT/US2010/040215; Filing date: June 28, 2010.

8. Simultaneous Detection and Relative Measurement of Multiple Analytes. Inventors: G Schultz, C Batich, E Tan, D Gibson. US Provisional Patent Application 61/137,192; Filing date: July 28, 2008.

Licensed Technologies

Page 19 of 38

1. QuickMed Technologies Antimicrobial coatings for wound dressings and medical devices, 1997 to present 2. QuickMed Technologies Anti-wrinkle cream formulation of ilomastat and phytoestrogen, 1997 to present 3. Abcam PLC Anti-Connective Tissue Growth Factor Mouse Monoclonal Antibody, 2006 to present 4. Novus Biologicals Anti-Connective Tissue Growth Factor Mouse Monoclonal Antibody, 2006 to present 5. Auxano Diagnostics, LLP Rapid point of care detector for MMPs, elastase and NOx, 2009 to 20011 6. Immuneyez, LLP Rapid point of care detector for MMPs, elastase and NOx, 2016 to present

LECTURES, SPEECHES OR POSTERS PRESENTED AT PROFESSIONAL CONFERENCES/MEETINGS. This listing is in reverse chronological order and is to be categorized by type of

meeting/conference, i.e., international, national, regional, state, local, etc. All lectures are invited presentations at professional conferences or meetings.

International Meetings (all are invited & sponsored presentations with multinational attendees) 1. Corneal Wound Healing – Scar Wars, International Ocular Surface Society, Baltimore, MD, May 6, 2017 2. Biofilms, European Wound Management Association, Amsterdam, May 4, 2017 3. Managing Infections in Chronic Wounds, Indonesian Wound Summit 2.0, Jakarta, Indonesia, March 11, 2017 4. Biofilm Management: Winning the Battle Against Biofilms, Indonesian Wound Summit 2.0, Jakarta, Indonesia, March

11, 2017 5. Antimicrobial Stewardship, ASEAN Expert Forum, Singapore, March 5, 2017 6. Chronic Wounds: A Global Perspective, ASEAN Expert Forum, Singapore, March 4, 2017 7. Biofilm Management: Getting It Right From the Start, ASEAN Expert Forum, Singapore, March 4, 2017 8. Wound Diagnostics: Identifying and Removing the Barriers to Healing. Japanese Society for Wound Healing, Tokyo,

Japan, December 9, 2016 9. Battling Biofilms: Winning the War in Wounds. Japanese Society for Wound Healing, Tokyo, Japan, December 9,

2016 10. Recommendations for Wound Biofilm Management: Results of a Global Consensus Panel, Wounds Australia,

Melbourne, Australia, November 11, 2016 11. Understanding Biofilms, Wounds Australia, Melbourne, Australia, November 10, 2016. 12. Winning the War in Wounds, Australian Wound and Tissue Repair Society, Melbourne, Australia, November 9, 2016. 13. Chronicity and Biofilm, World Union of Wound Healing Societies, Florence, Italy, September 28, 2016 14. Biofilm Challenge – What is Our Current Understanding? Wounds International Conference, Dubai, United Arab

Emirates, November 29, 2015 15. Disrupting Biofilm Activity Through Appropriate Use of Topical Antimicrobials, Wounds International Conference,

Dubai, United Arab Emirates, November 29, 2015 16. A Surfactant Based Autolytic Debrider and Biofilm Disrupter, Wound Healing: Science and Industry, San Juan,

Puerto Rico, December 12, 2015 17. Wound Infection: Detection and Identification, Wounds International Conference, Dubai, United Arab Emirates,

November 28, 2015 18. Debridement, Whose Problem Is It?, European Wound Management Association, London, May 14, 2015 19. What Is This Stuff On The Wound Bed? Sydney Diabetic Foot Conference, Sydney Australia, April 17, 2015 20. Biofilm Based Wound Care, Sydney Diabetic Foot Conference, Sydney, Australia, April 17, 2015 21. Negative Pressure Wound Therapy Plus Instillation – Effect on Biofilms, Sydney Diabetic Foot Conference, Sydney,

Australia, April 17, 2015 22. Identifying Chronic Diabetic Foot Ulcers with Elevated Protease Activities and Use of Corrective Therapies,

International Congress on Diabetes and Serious Complications, Varadero, Cuba, December 11, 2014 23. Battling Biofilms – Winning the War in Wounds, Wound Care Niagara, Niagara, Canada, March 26, 2014 24. Battling Biofilms – Winning the War in Wounds, Osaka and Tokyo, Japan, November 1-2, 2013 25. Advances in Diagnostics and Theranostics, New Zealand Wound Care Society Annual Meeting, Auckland, New

Zealand, May 24, 2013 26. Molecular Regulation of Wound Healing, New Zealand Wound Care Society Annual Meeting, Auckland, New

Zealand, May 23, 2013 27. Identifying and Treating Biofilms, New Zealand Wound Care Society Annual Meeting, Auckland, New Zealand, May

24, 2013 28. Role of Biofilms in Wound Healing - NPWT with Instillation, 3rd International Surgical Wound Forum, Istanbul,

Turkey, March 7-8, 2013 29. Microbicidal Coatings and Infection Control: Nonleaching Microbicidal Gauze Dressing, World Union of Wound

Healing Societies, Yokohama, Japan, September 5, 2012 30. In Vitro Models and Treatment Approaches for Biofilms, World Union of Wound Healing Societies, Yokohama,

Page 20 of 38

Japan, September 5, 2012 31. Anti-Scarring Therapies for Corneal and Conjunctival Injuries, 4th Scar Club Meeting, Montpellier, France, March 22,

2012 32. Chronic Wounds and Healing Challenges, Pan Pacific Pressure Ulcer and Venous Leg Ulcer Forum, Canberra,

Australia, October 16, 2011 33. Wound Diagnostics: Advancing Healing Outcomes, Pan Pacific Pressure Ulcer and Venous Leg Ulcer Forum,

Canberra, Australia, October 17, 2011 34. Management of Wound Exudate, Wounds International Conference, Cape Town, South Africa, February 3, 2011 35. Wound Assessment and Diagnosis, Wounds International Conference, Cape Town, South Africa, February 2, 2011 36. Biofilms Made Easy, Wounds International Conference, Cape Town, South Africa, February 1, 2011 37. MMPs as Diagnostic Tools for Chronic Wound Healing, Wound Diagnostics – An International Masterclass,

Manchester, UK June 30, 2010 38. Diagnostics and Infection in Wound Management, Wounds UK, Harrogate, UK, November 8-11, 2009 39. New Concepts in Wound Healing After Refractive Surgery, European Society of Cataract and Refractive Surgeons,

Barcelona, Spain, September 11-13, 2009 40. Basic Wound Healing Biology – Implications for Clinical Practice, Oxford-European Wound Healing Summer School,

Oxford UK, July 1-4, 2009 41. Inflammation: Friend or Foe, European Wound Management Association, Helsinki, Finland, May 20, 2009 42. Biomimetics: Nature’s Molecules as Templates for New Approaches to Wound Care, Wounds UK, Harrogate, UK,

November 10, 2008 43. Wound Bed Preparation Update, Japanese Society of Pressure Ulcers, Osaka, Japan, August 30, 2008 44. Wound Bed Preparation: A Focus on Inflammation and Infection, Japanese Society of Pressure Ulcers, Osaka,

Japan August 29, 2008 45. Guidelines for Prevention and Treatment of Pressure Ulcers, Japanese Society of Pressure Ulcers, Osaka, Japan,

August 29, 2008 46. Molecular Regulation of Wound Healing, Oxford-European Wound Healing Summer Program, Oxford, England, June

18-21, 2008 47. Dynamic Reciprocity in Difficult to Heal Wounds, Wound Union of Wound Healing Societies, Toronto, Canada, June

7, 2008 48. Diagnostics and Wound Care, Wound Union of Wound Healing Societies, Toronto, Canada, June 6, 2008 49. What Have We Learned About Why Wounds Won’t Heal? 7th Annual Australian Wound Management Association

Conference, Darwin Australia, May 7-10, 2008 50. How To Remove the Barriers to Healing in Chronic Wounds, Smith & Nephew Wound Update, Auckland, New

Zealand, May 12, 2008 51. I’s Wide Open Forum. Smith and Nephew Wound Forum, Melbourne, Australia, August 16-17, 2007 52. Application of Wound Bed Preparation in Chronic Wounds, 10th South American Congress of Diabetes, Buenos

Aries, Argentina, May 18-20, 2007 53. Proteases in Wound Healing, Industry and Science Symposium, St. Thomas, US Virgin Islands, December 8, 2006. 54. Advanced Wound Biology, Wounds UK, Harrogate, United Kingdom, November 13, 2006 55. Lung Fibrosis – Lessons Learned from Other Tissues, European Respiratory Society Annual Meeting, Munich,

Germany, September 3-6, 2006 56. The Importance of I in TIME: Infection and Inflammation, Wound Infection Institute meeting, Budapest, Hungary,

June 12, 2006 57. TIME: Molecular Basis for Wound Bed Preparation, Netherlands Wound Healing Society, Amsterdam, June 8, 2006 58. Hard to Heal Wounds: Molecular Basis for TIME, European Wound Management Association, Prague Czech

Republic, May 19, 2006 59. New Insights Into Regulation of Scarring, 10th French Congress on Wound Healing, Paris, France, January 16, 2006 60. Extracellular Matrix in Acute and Chronic Wounds. European Wound Management Association, Stuttgart Germany,

September 15, 2005 61. Wound Bed Preparation: Taking TIME to New Areas. European Pressure Ulcer Advisor Panel Annual Meeting,

Aberdeen, Scotland, UK, May 5, 2005 62. Corneal Gene Therapy. World Congress of Cornea V. Washington, D.C., April 14, 2005 63. Identifying and Correcting the Molecular Imbalances in Chronic Wounds, World Union of Wound Healing Societies,

Paris France, July 9, 2004 64. Scientific Basis for Wound Bed Preparation, Wounds UK 2003, Harrogate, United Kingdom, November 12, 2003 65. MMPs – Current Developments in Wound Biology, European J & J Wound Symposium, Hamburg, Germany,

October 14 -15, 2003 66. Future Developments in Wound Care, Innovations Seminar, Smith & Nephew, York, UK, September 25, 2003 67. Wound Bed Preparation, European Tissue Repair Society, Amsterdam, Netherlands, September 22, 2003 68. Molecular Characterization of Acute and Chronic Wounds, 4th Australian Wound Management Association Meeting,

Adelaide, Australia, March 7, 2002

Page 21 of 38

69. Molecular Approaches to Regulating Ocular Wound Healing, 11th Annual European Tissue Repair Conference, Cardiff, Wales, UK, September 5, 2001

70. mRNA Responses in Rat Corneas After PRK, M. Goldstein, and G.S. Schultz, XIV International Congress of Eye Research, Santa Fe, NM, October 15-18, 2000

71. Molecular Pathophysiology of Venous Ulcers. 1st World Wound Healing Congress, Melbourne, Australia, September 11-13, 2000

72. Cytokines and Proteases in Acute and Chronic Wounds. 8th Annual Meeting of the European Tissue Repair Society, Copenhagen, Denmark, August 27, 1998

73. Protease and Inhibitors in Corneal Wound Healing, XIII International Congress of Eye Research, Paris, France, July 27, 1998

74. Gene Therapy For Acute and Chronic Wounds, Australian Wound Management Association Meeting, Brisbane, Australia, January 10, 1998

75. Differential Expression of Cytokines in Acute and Chronic Human Wounds, 4th International Congress on The Immune Consequences of Trauma, Shock, and Sepsis, March 4 to 8, Munich, Germany, 1997

76. 3rd International Congress on Pelvic Surgery and Adhesion Prevention, February 29, 1996, San Diego, CA. 77. Modulation of Corneal Wound Healing, Oxford Ophthalmic Congress, Oxford, UK, July 2-5, 1995 78. Protease Levels in Healing and Chronic Human Wounds. Protease and Adhesion Molecules in the Pathophysiology

and Treatment of Cancer, Inflammation/Coagulation and Skin Disorders, Brodo/Ljubljana, Slovenia, June 4-8, 1994 79. Growth Factors and Proteases in Ocular Wound Healing. Singapore Nation Eye Center, December 13, 1993 80. Growth Factors and Ocular Wound Healing. XXIII Cambridge Ophthalmology Symposium, September 9-10, 1993 81. Growth Factors and Ocular Wound Healing, Wound Healing of the Ocular Surface & Paulo Foundation International

Medical Symposium, Helsinki, Finland, August 25-28, 1991 82. Neovascular Growth Factors, Cambridge Ophthalmological Symposium, St. John's College, Cambridge, England,

September 17-19, 1990

83. Transforming Growth Factor-Alpha (TGF-) and its Receptor in Neural Retina, Eight International Congress for Eye Research, San Francisco, September 4-8, 1988

84. Drugs That Modify Corneal Wound Healing, World Congress on the Cornea III, Washington, D.C., April 27-May 1, 1987

85. Effect of Growth Factors in Keratorefractive Surgery, World Refractive Surgery Symposium, Rome, Italy, May 2-4, 1986

86. Human Corneal Endothelial Cell Mitosis and Endothelial Grafting - Is it Possible in Corneal Surgery and Eye Banking, First International Cornea and Eye Banking Symposium, San Diego, CA, June 4-8, 1985

87. Action of Growth Factors on Corneal Wound Healing, Sixth International Congress for Eye Research, Alicante, Spain, October, 1984

National Meetings (all are invited presentations) (attendees primarily of one nationality) 1. Wound Scene Investigation Parts 1 & 2, Symposium on Advanced Wound Care, Las Vegas, Nevada, October 9,

2016 2. Biofilm Update, Symposium on Advanced Wound Care, Las Vegas, Nevada, October 7, 2016 3. Wound Scene Investigation Parts 1 & 2, Symposium on Advanced Wound Care, Atlanta, GA, April 23, 2016 4. Preventing Ulcer Recurrence, Symposium on Advanced Wound Care, Atlanta, GA, April 22, 2016 5. Biofilms, What We Know and Don’t Know, Symposium on Advanced Wound Care, Atlanta, GA, April 21, 2016 6. Bacterial Biofilms: Effects on Wound Healing. American Venous Forum, Orlando, FL, February 24, 2016.

7. Biofilm Update, Symposium on Advanced Wound Care, Las Vegas, NV, September 28, 2015 8. Breaking Down the Barriers to Wound Healing: Selective Debridement for Effective Wound Bed Preparation,

Symposium on Advanced Wound Care, Las Vegas, NV, September 27, 2015 9. MMPs and How Collagen Dressings Balances Them to Break the Chronic Cycle of ECM Degradation, Clinical

Symposium on Advances in Skin and Wound Care, New Orleans, LA, September 21, 2015 10. Biofilm Management, Clinical Symposium on Advances in Skin and Wound Care, New Orleans, LA, September 19,

2015 11. Wound Biofilm: The Evolving Science and Clinical Management, Wound Ostomy Continence Nurses Annual

Meeting, San Antonio, TX, June 8, 2015 12. Wound Scene Investigation Parts I & II, Symposium on Advanced Wound Care, San Antonio, TX, May 2, 2014 13. Biosurgery: Medical Larval Debridement, Symposium on Advanced Wound Care, San Antonio, TX, May 1, 2014 14. The Science of Chitosan and Hyaluronic Acid: What Did Nature Design Into These Biomaterials? John A Boswick

Burn and Wound Symposium, February 15, 2015, Maui, Hawaii. 15. Wound Scene Investigation Parts I & II, Symposium on Advanced Wound Care, Las Vegas, NV, October 27, 2014 16. Understanding the Microwound Environment as a Key to Optimizing Healing Outcomes, Healogics National

Physician Meeting, Las Vegas, NV, October 15, 2014 17. MMPs and How Collagen Dressings Rebalance Them to Promote Healing, Clinical Symposium on Advanced Wound

Care, Las Vegas, NV, September 30, 2014

Page 22 of 38

18. Infection - I Know It When I See It or Do I, Clinical Symposium on Advanced Wound Care, Las Vegas, NV, September 29, 2014

19. Healing Through Natural Chemistry: Clinical Applications of Collagen Dressings, Amniotic Membranes, Chitosan Dressings and Medical Honeys. Science and Industry 8th Annual Meeting, San Juan, Puerto Rico, June 28-28, 2014

20. Biofilms and Impact on Wound Healing, North American Negative pressure Wound Therapy Summit, Dallas, TX, May 2-3, 2014

21. Wound Scene Investigation Parts I & II, Symposium on Advanced Wound Care, Orlando, FL, April 27, 2014 22. Role of PDGF in Wound Healing - Facilitating Closure of Neuropathic Ulcers, Symposium on Advanced Wound Care,

Orlando, FL, April 26, 2014 23. Biofilms is Your Strategy Working? Getting it Right From the Start, Symposium on Advanced Wound Care, Orlando,

FL, April 24, 2014 24. Bioburde; Cellular and Diagnostic Tools Available, American Professional Wound Care Association, Philadelphia,

PA, March 22, 2014 25. Wound Scene Investigation Parts I & II, Symposium on Advanced Wound Care, Las Vegas, NV, September 29,

2013 26. Interactive Case-Based Model to Manage Diabetic Foot Ulcers: The Role of Platelet-Derived Growth Factor,

Symposium on Advanced Wound Care, NV, September 28, 2013 27. NPWT + Instillation vs Biofilms – What Works in the Lab? Technology Innovations in Plastic Surgery, San Francisco,

CA, May 31, 2013 28. Wound Scene Investigation Parts I & II, Symposium on Advanced Wound Care, Denver, CO, May 3, 2013. 29. Basics of Wound Healing – Debridement and Infection, Wound Healing Society Annual Meeting, Denver, CO, May 2,

2013 30. Interactive Case-Based Model to Manage Diabetic Foot Ulcers: The Role of Platelet-Derived Growth Factor,

Symposium on Advanced Wound Care, Denver, CO, May 3, 2013 31. NPWT with Instillation – Effects on Biofilms, American College of Surgeons, Washington, DC, October 7, 2013 32. Wound Scene Investigation Parts I & II, Symposium on Advanced Wound Care, Atlanta, GA September 29, 2013 33. Dynamic Reciprocity – Interactions Between ECM and Cells, Desert Foot Conference, Phoenix, AZ, November 14,

2012 34. Venous Leg Ulcers: What’s Down the Pike? Symposium of Advanced Wound Care, Baltimore, MD, September 13,

2012 35. Innovative Strategies for Healing Venous Leg Ulcers: Clinical Applications of Dehydrated Amniotic Membranes,

Symposium of Advanced Wound Care, Atlanta, GA, April 22, 2012 36. Diagnostics and Theranostics, Symposium of Advanced Wound Care, Atlanta, GA, April 22, 2012 37. Infection and Biofilms, Symposium of Advanced Wound Care, Atlanta, GA, April 19, 2012 38. Biofilms and Bioburden - What’s the Big Deal? American Professional Wound Care Association, Orlando, FL, April 1,

2012 39. Biofilms – A Clinical Conundrum. Canadian Association of Wound Care, Ottawa, CA November 5, 2011 40. Diagnostic Dilemma: Infection vs Inflammation. Canadian Association of Wound Care, Ottawa, CA November 5,

2011 41. Biofilms, Symposium on Advanced Wound Care, Las Vegas, NV, October 13, 2011 42. Biofilms and Wound Exudate, Infection and Inflammation Forum, Melbourne, Australia, August 12, 2011 43. Basics of Wound Care – Debridement and Infection Control, American Geriatrics Society, Washington DC, May 11,

2011 44. Emerging Wound Diagnostic Technologies, Symposium on Advanced Wound Care, Dallas Texas, April 17, 2011 45. Wound Scene Investigation I and II – Linking Science and Clinical Care, Symposium on Advanced Wound Care,

Dallas Texas, April 15 and 16, 2011 46. Wound Bed Preparation – Debridement and Infection Control, Basics of Wound Care Pre-Conference Session,

Wound Healing Society, Dallas Texas, April 14, 2011 47. Emerging Technologies: What The Future Holds, Clinical Symposium of Advanced Skin and Wound Care, Orlando

Florida, October 2, 2010 48. Banishing Biofilms, Symposium of Advanced Wound Care, Symposium of Advanced Skin and Wound Care, Orlando

Florida, October 2, 2010 49. Biofilm Based Chronic Wound Care, Symposium on Advanced Wound Care, Anaheim, California, September 25,

2010 50. Biochemistry of the Wound Bed, Canadian Association of Enterostomal Therapy, Niagara, Canada, May 29, 2010 51. Wound Bed Preparation and Infection Control, American Geriatrics Society, Orlando, Florida, May 12, 2010 52. Wound Diagnostics: The Future is Near, Symposium on Advanced Wound Care, Orlando, Florida, April 18, 2010 53. Molecular Regulation of Acute Wound Healing: Dysregulation in Chronic Wounds, Strategic Wound Care

Symposium, Winnipeg Regional Health Authority, Winnipeg, Canada, March 26, 2010 54. Biofilm Based Chronic Wound Care, Strategic Wound Care Symposium, Winnipeg Regional Health Authority,

Winnipeg, Canada, March 26, 2010

Page 23 of 38

55. Biofilms and the Chronic Wound Bed, Clinical Symposium on Advances in Skin & Wound Care, San Antonio, Texas, October 24, 2009

56. Angiogenesis Research: Translating from Bench to Bedside, Clinical Symposium on Advances in Skin & Wound Care, San Antonio, Texas, October 23, 2009

57. Wound Care Essentials: Acute and Chronic Wound Healing, Clinical Symposium on Advances in Skin & Wound Care, San Antonio, Texas, October 22, 2009

58. Biofilms: What Do We Really Know? Symposium on Advanced Wound Care/Wound Healing Society, Dallas, TX, April 27, 2009

59. Matrix Degradation. Wound Healing Society Annual Meeting, Dallas, Texas, April 27, 2009 60. How Does a Biofilm Retard Healing? National Pressure Ulcer Advisory Panel Biennial Meeting, Washington DC

February 28, 2009 61. Proteases and Detectors in Wound Care, Wound Healing: Science and Technology, St. Thomas, U.S. Virgin Islands,

December 13-16, 2007 62. On Biofilms in Wounds. Wound, Ostomy, Continence Nurses Annual Meeting, Salt, Lake City, UT, June 10, 2007 63. Future Developments in Advanced Wound Care, Symposium of Advanced Wound Care, Tampa, FL, April 29, 2007 64. The TIME Concept, VEITH Symposium, New York, NY, November 15, 2006 65. Proteases: Good and Bad, Symposium on Advanced Wound Care, San Antonio, TX, May 3, 2006 66. Scar Wars: Corneal Wound Healing, Association for Research in Vision and Ophthalmology, April 31, 2006 67. MMPs: Regulation and Repair. Wound Healing: Science and Technology, St. Thomas, U.S. Virgin Islands,

December 9-11, 2005 68. A Look at Healing Deep in the Wound. Clinical Symposium on Advances in Skin & Wound Care, Las Vegas, NV,

October 24, 2005 69. A Common Molecular Mechanism for Fibrosis in Tissues. Society of Vascular Surgeons, Washington, D.C., April 7,

2005 70. Metalloproteinases and the Use of Doxycycline Treatment to Improve Healing, American Academy of Dermatology,

New Orleans, LA, February 21, 2005 71. Matrix Metalloproteinases: Regulation and Repair. Wound Healing: Science and Technology, St. Thomas, U.S.

Virgin Islands, December 10-12, 2004 72. What to do When Wounds Won’t Heal. Canadian Association of Wound Care, Calgary, Alberta, Canada, November

20, 2004 73. Stem Cells in Wound Healing, Program Organizer, Symposium on Advance Wound Care, Orlando, FL, May 2, 2004 74. Understanding the Chronic Wound, Symposium on Advanced Wound Care, Las Vegas, NV, April 28, 2003 75. Molecular Approaches in the Treatment of Ulcerative Keratitis, Thygeson Lectureship, Ocular Microbiology and

Immunology Group meeting, October 19, Orlando, FL, 2002. Molecular Pathophysiology of Chronic Wounds, Association of Advanced Wound Care Symposium, Miami, April 21, 1998

76. Growth Factors and Wound Healing, 1st Ethicon Endo-Surgery Lectureship, American Society for Reproductive Medicine, Cincinnati, Ohio, October 21, 1997

77. Corneal Wound Healing, Everett Kinsey Lecture, Contact Lens Association of Ophthalmologist, Las Vegas NV, January 16 to 18, 1997

78. Regulation of Corneal Wound Healing by Growth Factors, Keystone Symposium on Ocular Cell and Molecular Biology, Tamarron, Colorado, January 7 to 12, 1997

79. Biochemical Analysis of Human Wound Fluids. Fourth Annual Research Forum on Wound Repair, University of Miami, April 28 to May 1, 1994

80. EGF and TGF- in Wound Repair, UCLA Conference on Progress in Basic Research of Wound Repair and its Application to Clinical Management of Problem Wounds. Breckenridge, CO. April 3, 1993

81. The Use of Growth Factors in Promoting Wound Healing, Washington State Ophthalmological Society Meeting, Seattle, WA, September 21, 1991

82. EGF and Wound Therapy, UCLA Symposium on Wound Repair. Keystone, CO April 7, 1991. 83. Growth Factors, 15th Clinical Congress of the American Society of Parenteral and Enteral Nutrition, San Francisco,

CA, January 26, 1991 84. Overview of Growth Factors and Wound Healing II, Technology Management Group, Boston, MA, December 6-7,

1990

85. EGF and TGF- in Wound Healing and Repair, UCLA Symposium on Tissue Engineering, Key Stone, CO., April 6-12, 1990

86. Overview of Growth Factors in the Eye, Annual Meeting of the Association for Research in Vision and Ophthalmology Association, Sarasota, Florida, April 30, 1989

87. EGF in Corneal Wound Healing, Visions in Wound Healing, Innisbrook, Florida, March 16-18, 1988 88. Candidate Agents to Enhance Wound Healing, American Society of Cataract and Refractive Surgery, Los Angeles,

CA, March 29, 1988 89. Biosynthetic Growth Factors and Wound Healing, Industrial Biotechnology Association, Naples, Florida, February 16-

18, 1988

Page 24 of 38

90. Development of Epidermal Growth Factor and Its Uses in Wound Healing, Growth Factors for Wound Healing, symposium sponsored by Technology Management Group, Inc., New Haven, CT, November 1-3, 1988

91. Topical Epidermal Growth Factor, Castroviejo Society Symposium, Las Vegas, Nevada, January 14, 1988 92. Pre-Clinical Application of Biosynthetic EGF, American Tissue Culture Association. Ohio Valley Branch, Columbus,

OH, April 3, 1986

University Presentations (all invited presentations) (attendees primarily from one university) 1. Update on Wound Healing, University of Florida, Dept ObGyn, March 17, 2017

2. Scar Wars: Development of Antiscarring Therapies for Cornea, Conjunctiva and Skin, Oklahoma University Dean McGee Eye Institute, Oklahoma City, OK, April 22, 2016

3. Battling Biofilms - Winning the War in Wounds, University of Rochester, Rochester NY, October 23, 2015.

4. Development of Gene-Targeted Anti-Scarring Therapies, Texas Tech University, Lubbock, TX, January 26, 2015

5. Biofilms in Orthopaedics, University of Florida, Gainesville, FL, January 14, 2014

6. Molecular Regulation of Corneal Scarring – Applications of Antisense Oligonucleotides, siRNAs and Epigenetic Modifiers, Harvard University and Schepen’s Eye Research Institute, Boston, MA, January 25, 2013

7. Anti-Scarring Therapies Using Antisense Oligonucleotides and siRNAs Targeting CTGF In Both Animal Models and In Clinical Trials, University of British Columbia, April 10, 2012

8. Molecular and Cellular Regulation of Normal and Chronic Wounds – What Goes Wrong When Acute Wounds Fail to Heal? University of Washington School of Nursing, Update on Wound Management, Seattle, WA, November 17, 2011

9. Bacterial Biofilms – What is This Slim and How Do I Treat It? University of Washington School of Nursing, Update on Wound Management, Seattle, WA, November 17, 2011

10. Bioburden in Wounds - State of the Science, University of Nebraska, Omaha, Nebraska, November 11, 2010 11. Biofilms - A Common Culprit in Non-Healing Wounds, of Nebraska, Omaha, Nebraska, November 12, 2010 12. Biofilms and Chronic Inflammation, Ohio State University Comprehensive Wound Center Wound Care and

Hyperbaric Update, Columbus, Ohio, March 27, 2010 13. Development of an In Vitro Pig Skin Wound Model Of Mature Biofilms, Montana State University, Bozeman,

Montana, February 4, 2009 14. Scar Wars: Molecular Regulation of Ocular Wound Healing, University of South Florida, Tampa, Florida, January 26,

2007 15. Molecular Regulation of Scarring, University of Louisville, Louisville, Kentucky, January 19, 2007 16. Scar Wars: Regulation of Ocular Scarring, Bascom Palmer Eye Institute, University of Miami, Miami Florida, May 1,

2003 17. Modulation of Corneal Wound Healing, Joseph M. Bryan Lecturer, Duke University, Durham, North Carolina, January

11, 1995 18. Biochemical Analysis of Human Wound Fluids, Medical and Dental College of New Jersey, Camden, New Jersey,

January 5, 1994 19. EGF and its Receptor in Cornea and Wound Healing, University of Kansas Medical Center, Kansas City, Kansas,

April 5, 1990 20. Modulation of Corneal Wound Healing by Growth Factors, Emory University, Atlanta, Georgia, September 16, 1988 21. Molecular Mechanism of Regeneration of Wound Healing by Growth Factors, Memorial Sloan-Kettering Cancer

Center, New York, NY, February 26, 1988 22. Acceleration of Corneal Wound Healing by Biosynthetic Human EGF, University of Oklahoma, Department of

Ophthalmology, Oklahoma City, Oklahoma, March 26, 1984 23. Symposium on Renin-Angiotensin System: Enzymology, Receptor and its Role in Understanding Hypertension,

University of Kentucky, Lexington, Kentucky, April 20, 1981

Local Meetings (all are invited presentations) (local attendees) 1. Wounds and Biofilms, Heal Ohio, Akron, OH, October 27, 2016 2. Preventing Ulcer Recurrence - How to Keep Them Closed, 2016 Wound Symposium, Munster, IN, October 15, 2106 3. Wound Healing: Lessons from the Skin and Cornea, Vision Research Center, University of Florida, Gainesville, FL,

June 6, 2016 4. MMPs and Wound Healing, Wyoming Skin and Wound Symposium, Sheridan, Wyoming, June 2, 2016 5. Drugs and the Wound Care Patient, Wyoming Skin and Wound Symposium, Sheridan, Wyoming, June 2, 2016 6. Cell and Tissue Products for Wound Care, Wyoming Skin and Wound Symposium, Sheridan, Wyoming, June 2,

2016 7. Wound Infection & Biofilms, Rocky Mountain Region Wound Ostomy Continence Nurses annual meeting, Phoenix,

AZ, September 11, 2015 8. Battling Biofilms: Winning the War in Wounds, Southeast Region Wound Ostomy Continence Nurses annual

meeting, Orlando, FL September 10, 2015

Page 25 of 38

9. Wound Healing and Proteases, Northeast Wyoming Skin and Wound Symposium, Sheridan WY, June 5, 2015 10. The Process of Wound Healing, Northeast Wyoming Skin and Wound Symposium, Sheridan WY, June 4, 2015 11. Battling Biofilms – How to Win the War in Wounds, Florida Association of Enterostomal Therapists, Gainesville, FL,

March 1, 2014 12. Battling Biofilms – How to Win the War in Wounds, Vancouver, Edmonton, Saskatoon, and Winnipeg, Canada,

February 24 – 28, 2014 13. Dynamic Reciprocity – How Cells and Extracellular Matrix Communicate to Heal Wounds, Colorado Foot & Ankle

Surgeons Society, Denver, CO, October 25, 2013 14. Wound Healing and Biofilms, South Central Region of Wound Ostomy Continence Nurses, Memphis, TN, October

11, 2013 15. Molecular and Cellular Regulation of Normal and Chronic Wounds – What Goes Wrong When Acute Wounds Fail to

Heal? Northwest Regional Wound Ostomy Continence Nurses Meeting, Portland, OR, October 26, 2012 16. Bacterial Biofilms – What is This Slim and How Do I Treat It? Northwest Regional Wound Ostomy Continence

Nurses Meeting, Portland, OR, October 26, 2012 17. Biology & Biochemistry of Wound Healing, 4th Annual Overlook Hospital Symposium on Wound Healing & Hyperbaric

Medicine, Summit, NJ, November 4, 2011 18. Biofilm Based Wound Care, Mid-Atlantic WOCN Conference, Richmond, Virginia, October 29, 2010. 19. Biofilm Based Wound Care, Great Falls, Montana, October 7, 2010 20. Biofilm-Based Wound Care, Skin Deep and More: Annual Wound and Skin Conference, Shands Hospital,

Gainesville, FL, May 19, 2010 21. Molecular and Cellular Mechanism of Wound Healing, 2nd Atlantic Health Wound Symposium, Summit, New Jersey,

October 16, 2009 22. Wound Fluids: Biomarkers of Healing, Baptist Health South Florida, Miami, FL, September 26, 2009 23. From Bench to Bedside: Translating Research into Implementation, Baptist Health South Florida, Miami, FL,

September 26, 200. 24. Wound Healing Latest Science, Wound Ostomy Continence Nurses Association, North Central Branch, St. Paul MN,

September 19, 2009 25. Chronic Wounds, Community Health and Family Medicine Grand Rounds, University of Florida, November 8, 2007 26. Update on Wound Healing, Dermatology Grand Rounds, University of Florida, October 19, 2006 27. Wound Healing, Dermatology Grand Rounds, University of Florida, April 28, 2005 28. Molecular Regulation of Wound Healing, Florida Wound Care Symposium, Gainesville, FL, February 7, 1998 29. Biochemical Analysis of Acute and Chronic Wounds, University of Miami, October 3, 1997 30. Hormonal Regulation of Wound Healing, Collagen Corp., San Francisco, CA, June 1, 1985 31. Role of EGF and TGF in Breast Cancer. Oncogen, March 20, 1984 32. A Mini Symposium on Potential Application of EGF in Surgery. Chiron Corporation, February 20, 1984 33. Peptide Growth Factors: Comparison of in vitro and in vivo effects. Ohio Valley Tissue Culture Association, Miami

University, October, 1983

GRANT SUPPORT AS PRINCIPLE INVESTIGATOR, CO-PI, or Co-Investigator

GRANT TITLE ACTIVE AGENCY DATES TOTAL AWARD

GS ROLE % Effort

1. Effects of Nevada Naturals Solution on Mature Biofilms On Pig Skin Explants

Nevada Naturals 12-01-16 to 06-91-17

$ 20,000 PI 5%

2. Gene Therapy in the Cornea NIH RO1 EY017294 subcontract

05-01-14 to 04-30-19

$ 187,438 PI 5%

3. Effects of Taurolidine on Preventing Biofilm Formation on Catheters and Skin Wounds

Cormedix, Inc. 01-01-17 to 01-01-18

$ 50,000 PI 10%

4. Quantifying Biofilms on Hemodialysis Catheters from Patients Treated with Neutrolin Solution

Cormedix, Inc. 01-15-17 to 01-15-18

$ 100,000 PI 10%

5. Clinical Effect of 3M Solution on Biofilm in Chronic DFU and VLU 3M Wound Care Division

02-01-17 to 12-31-18 $ 140,000 PI 15%

6. Effects of Enterade on Accelerating Healing of Corneal Excimer Ablation Wounds

Entrinsic Health Solutions, LLC

02-15-17 to 12-15-17

$ 40,000 PI 5%

7. Effects of Next Science Wound Gel on Biofilms in Chronic Wounds Next Science, Inc

02-01-17 to 12-15-17

$ 10,000 PI 5%

Page 26 of 38

8. Effects of Puraply AM on Proliferation of MRSA in a Porcine Partial Thickness Wound Model Organogenesis

03-01-17 to 07-01-17

$ 45,270 PI 5%

TOTAL ACTIVE

$ 592,708

GRANT TITLE COMPLETED AGENCY DATES TOTAL AWARD

GS ROLE % Effort

1. Angiotensin II Receptors of Aortic Endothelial Cells

NIH RO1 HL-26202

08-01-80 to 07-31-83

$ 149,904 PI

2. Role of Epidermal Growth Factor Receptor in Breast Cancer

NIH RO1 CA-31895 NIH RO1 NIH RO1

04-01-82 to 03-31-85

$ 158,836 PI

3. Action of Biosynthetic Human EGF on Burns and Cornea

Chiron, Corp. 04-01-84 to 03-31-85

$ 21,600 PI

4. Enhanced Corneal Wound Healing by Fibroblast Growth Factor

Fight for Sight 09-01-82 to 08-31-83

$ 11,491 PI

5. Characterization of AT-II Receptors on Vascular Cells

Kentucky Heart Association

07-01-80 to 06-30-81

$ 15,120 PI

6. Biosynthetic Human EGF Action on Corneal Wound Healing

NIH RO1 EY-05587-04

12-01-84 to 11-30-87

$ 188,152 PI

7. Corneal Wound Healing: Regulation by Growth Factor

NIH RO1 EY-05587-08

12-01-87 to 06-30-92

$ 336,660 PI

8. Reversal of Atherosclerosis by Lipoproteins in Cell

Kentucky Heart Association

07-01-82 to 06-30-83

$ 14,815 PI

9. Acceleration of Wound Healing Following Epikeratophakia

American Medical Optics 11-01-84 to10-31-85

$ 64,771 Pi

10. Effects of Biosynthetic Human EGF on Wound Healing

U.S. Army MRDC 08-01-85 to 09-30-87

$ 155,552 PI

11. Evaluation of Interleukin 1 on Epidermal Regeneration

Immunex Corp 11-01-87 to 08-31-88

$ 41,760 PI

12. Cataract Incision Healing with Growth Factor Ethicon, Inc 03-15-87 to 12-01-89

$ 179,186 PI

13. Actions of Growth Factors on Corneal Wound Healing

Chiron Ophthalmics 09-01-86 to 12-01-89

$ 280,784 PI

14. Effect of EGF on Corneal Endothelial Cells IO Lab 11-13-89 to 01-02-90

$ 12,352 PI

15. Enhancement of Wound Healing by Biosynthetic Growth Factors

U.S. Army Res & Develop U.S. Army 10-01-86 to 09-30-88

$ 568,395 Co-PI Brown

16. Enhancement of Wound Healing by Biosynthetic Growth Factors

U.S. Army Res & Develop 07-31-91 to 07-31-95

$ 321,778 PI

17. Evaluation of New Contact Lenses Vistakon 04-01-94 to 03-31-97

$ 174,000 PI

18. Development of New RT-PCR Plasmids Pfizer Inc. 09-01-96 to 04-30-98

$ 55,675 PI

19. Evaluation of Intraocular Lens Material Chiron Vision 0 4-01-97 to 03-31-98

$ 6,500 PI

20. Evaluation of Levofloxacin in Epithelial Wound Healing

Santen Inc. 07-01-97 to 01-31-99

$ 94,614 PI

21. Sequential Cytokine Therapy for Chronic Wounds

NIH NIAMSD 10-01-96 to 02-28-99

$ 26,580 PI

22. Evaluation of PHM-101 in Corneal Wound Healing

Phairson Ltd. 02-15-99 to 02-15-01

$ 85,440 PI

23. Corneal Wound Healing: Regulation by Growth Factor

NIH RO1 EY 05587-12 07-01-92 to 06-30-97

$ 564,218 PI

24. Regulation of Stromal Wound Healing by Growth Factors

NIH RO1 EY 05587-16 06-30-97 to 07-01-02

$1,080,674 PI

25. Assessment of Oxynor Peptides on Ischemic Wound Healing

Fabre-Kramer Pharm 10-01-01 to 12-30-02

$ 85,560 PI

26. Alpha-1 Protease Inhibitor in Otitis Media and Arriva Pharm. 09-01-01 to $ 128,782 Co-PI

Page 27 of 38

Otitis Externa 12-30-03 Antonelli

27. Effect of Acticoat Dressing on Cytokines and MMPs in Chronic Wounds

Smith & Nephew 08-01-00 to 12-31-03

$ 254,006 Co-PI Mozingo

28. Treatment of Diabetic Foot Ulcers with a Protease Inhibitor, Doxycycline

VA Merit II 10-01-01 to 09-30-04

$ 155,000 Co-PI Chin

29. Tympanic Membrane Healing with Topical Ciprodex Therapy

Alcon Labs 11-01-04 to 1-31-05

$ 61,769 Co-PI Antonelli

30. Evaluation of Topical Proteases in Pressure Ulcers

Swiss American Products 05-01-05 to 12-30-05

$ 49,980 Co-PI Stechmiller

31. Analysis of Antiviral Activity of pDADMAC QuickMed Technologies 05-01-05 to 09-30-05

$ 18,698 Co-PI Bloom

32. Microarray Analysis of Apligraf Effects On Gene Expression

Organogenesis 06-01-06 to 12-31-06

$ 28,944 PI

33. Effect of Dermax on Gene Expression in Normal & Diabetic Human Fibroblasts

Greystone Pharmaceticals

1-01-05 to 12-31-06

$ 26,243 PI

34. Regulation of Stromal Wound Healing by Growth Factors

NIH RO1 EY 05587-21

04-01-02 to 03-31-07

$1,726,206 PI

35. Evaluation of Serum Amyloid Protein In Trabeculectomy Scar Reduction

Medior Pharmaceuticals 10-01-06 to 11-30-07

$ 45,671 Co-PI Sherwood

36. Assessment of PHI on MMP Production In Cultures of Human Fibroblasts

Greystone Pharmaceuticals

07-01-07 to 10-31-07

$ 25,000 PI

37. Rapid Diagnostic and Biofilms in Chronic Wounds

Auxano Diagnostics 08-01-07 to 07-31-08

$ 100,000 PI

38. Evaluation of Ilomastat for Treatment of Sulfur Mustard Injuries to Eye and Skin

US Army CRADA 04-01-07 to 03-31-08

$ 105,415 PI sub-contract

39. Wound Dressings Designed to Speed Closure Following Debridement of Cutaneous Vesicant Injuries

US Army SBIR Phase I & II

09-14-07 to 02-14-09

$ 106,500 PI

40. Prevention of Glaucoma Scarring Using Saratin Injections

BioVasc, Inc 05-50-09 to 12-31-09

$ 113,262 Co-PI Sherwood

41. Effect of Anti-S1P in Reducing Glaucoma Scarring in Rabbits

Lpath, Inc 06-01-09 to 12-31-09

$ 121,887 Co-PI Sherwood

42. Innovative Intervention for Healing of Diabetic Ulcers

NIH R15 NR09377-01

04-01-05 to 03-31-10

$ 212,381 Co-PI Stechmiller

43. Molecular Epidemiology of Recurrent Aphthous Ulcers Role of Ghrelin

NIH R29 DE018714 09-08-08 to 08-31-10

$ 362,088 Co-Invest Baccaglini

44. Effect of NPWT on Biofilms on Pig Skin Explants

Kinetic Concepts, Inc 09-01-09 to 02-28-10

$ 71,998 PI

45. Biofilm and Proteomic Analysis of Chronic Wounds

Health Point, Inc 12-01-09 to 11-31-10

$ 137,994 PI

46. Mechanism of Action of Cadexomer Iodine on Bacterial Biofilms

Smith & Nephew, Inc 11-01-09 to 08-31-10

$ 63,000 PI

47. Preclinical Study of Mesenchymal Stem Cells in Impaired Wound Healing

Cyro-Cell 08-01-10 to 06-31-11

$ 43,204 PI

48. Markers for Lung Transplant Rejection Role of Type V Collagen

UF FCPA 10-01-10 to 06-31-11

$ 90,000 Co-Invest Batich

49. Regulation of Stromal Wound Healing by Growth Factors

NIH RO1 EY 05587-25

04-01-07 to 03-31-12

$1,366,595 PI

50. Gene Therapy in the Cornea NIH RO1 EY017294 12-01-06 to 03-31-12

$ 223,500 PI sub-contract

51. Identification of Therapeutics for Treatment of Sulfur Mustard Injury

NIH U54 NS058185-01 10-01-06 to 09-30-12

$ 1,156,532 PI sub-contract

52. Reduction of Corneal Scarring Following Blast & Burn Injuries Using siRNA

US Army MRDC W81XWH1010917

10-01-10 to 03-31-13

$ 843,476 PI

53. Effects Of Silicone Faced Dressings On Development Of Pseudomonas Aeruginosa Biofilms On Porcine Skin Wounds Model

Medline Industries 01-10-13 to 08-21-13

$ 7,000 PI

54. Evaluation of Microbicidal Effects of TheraHoney Gel Combined with Three Silver Dressings on Planktonic Bacteria In Two In

Medline Industries 02-01-13 to 09-15-13

$ 7,000 PI

Page 28 of 38

Vitro Models

55. Comparative Assessment of Osmotic Activity of TheraHoney Gel Dressing on Silver Releasing Hydrogel or Alginate Dressings

Medline Industries 01-01-13 to 08-07-13

$ 5,000 PI

56. Biomechanical Characterization of Two Sacral Dressings

Medline Industries 01-10-13 to 07-11-13

$ 15,000 PI

57. Antimicrobial Efficacy Of Negative Pressure Wound Therapy (NPWT) Using Microcyn Solution Against Pseudomonas aeruginosa Biofilm On Pig Skin Explants

Eloquest Healthcare 04-01-13 to 06-30-13

$ 48,985 PI

58. A Prospective, Single-Center, Single-Blinded, Non-Comparative, Post-Market Clinical Evaluation Of Manukamed Topical Dressing Under Compression For The Management Of Infected Venous Leg Ulcer

Manukamed 01-01-13 to 12-31-13

$ 45,000 PI

59. Effect of Plasma PlasmaJet System On Pseudomonas aeruginosa Biofilm on Pig Skin Explants

ArthroCare 06-01-13 to 08-31-13

$ 13,747 PI

60. Measurements of MMPs and Cytokines in Wound Fluids Of Patients Treated with Endoform

Hollister Wound Care 10-09-11 to 12-31-12

$ 146,485 PI

61. Effects of PHI+ on Corneal Epithelial Wound Healing

Red Oax, LLC 08-15-13 to 12-15-13

$ 31,013

Co-Invest D. Gibson PI

62. Gene Therapy in the Cornea NIH RO1 EY017294

12-01-12 to 08-31-14

$ 37,250 PI sub-contract

63. Effect Of Coblation Combined With NPWT On Mature Biofilms Grown On Pig Skin Explants

Arthrocare Phase 2

04-01-14 to 05-01-14

$ 32,021 PI

64. Regulation of Stromal Wound Healing by Growth Factors

NIH RO1 EY005587-25

09-01-12 to 08-31-14

$ 386,064 PI 20%

165. Assessment of APIC on Proteases in Chronic Wound Fluid Samples

Cytonics Corporation 05-20-14 to 08-30-14

$ 15,000 PI 5%

66. Nitric Oxide Releasing Topical Products for Chronic Wounds And Associated Biofilms

iFyber LLC, NCI HHSN2610130091C NIH SBIR sub-contract

09-27-13 to 09-26-14

$ 63,354 PI 15%

71. Biofilm Measurements In Chronic Wounds Treated With Iodosorb

Smith & Nephew A02 proposal

07-01-14 to 12-31-14

$ 30,840 PI 10%

68. Creation Of Comparative Data Showing Performance Of Cadex Vs Competitor Product

Smith & Nephew A01 proposal

09-11-13 to 12-31-14

$ 30,000 PI 10%

69. Biofilm Measurements In Patients Treated With VAC + Microcyn Solution

KCI subcontract from Columbia University

01-01-14 to 12-31-14

$ 89,964 PI 5%

70. Microbicidal Effects Of Different Instillation Fluids On Biofilms On Pig Skin Explants

Kinetic Concepts, Inc. 03-01-14 to 12-30-14

$ 60,000 PI 5%

71. Testing the Aldehyde Trap NS2 in A Rabbit Corneal Scarring Model

Aldeyra Therapeutics, Inc

07-14-14 to 12-31-14

$ 89,854 Co-I 5%

72. Advanced Micro-Patterned Wound Dressings for Enhanced Epithelialization

Sharklet Technologies NIH SBIR subcontract

01-01-15 to 07-30-15

$ 42,623 PI 10%

73. Testing Debrisoft On Debriding Bacterial Biofilms Grown On Pig Skin Explants

Lohmann & Rauscher 10-15-14 to 09-15-15

$ 30,000 PI 10%

74. Multiphase Assessment of a Plasma Surgery Surgical Device

Plasma Surgical 10-15-14 to 09-15-15

$ 57,000 PI 10%

75. Effects of Microbicidal Solutions on Pig Skin Explant Biofilms

3M Company 08-01-15 to 12-31-15

$ 48,749 PI 10%

76 . Regulation of Stromal Wound Healing by Growth Factors

NIH RO1 EY005587-26

09-01-14 to 08-31-16 $ 378,733 PI 40%

Page 29 of 38

77. Cognitive Behavioral Effects On Sleep, Pain, And Cytokines In Gynecologic Cancer Patients

NIH RO1 CA138808 D. Pereira PI

08-20-14 to 05-31-16

$ 22,912

Co-Inv 5%

78. Effect of J-Plasma Treatment on Planktonic and Biofilm Bacteria on Pig Skin Explants

Bovie Medical Corporation

01-15-16 to 12-01-16 $ 12,000 PI 5%

Total

Completed $14,078,142

TOTAL GRANTS AWARDED ACTIVE + COMPLETED

$14,650,850

TRAINING GRANTS, CORE GRANTS, K08 GRANTS

TRAINING GRANT TITLE ACTIVE AGENCY DATES TOTAL COSTS

GS ROLE

1. Research Training in Vision Science NIH T32 EY07132-17

10-01-09 to 09-30-14

$ 1,250,000 Mentor Co-Invest

2. Research in Cardiovascular Diseases American Heart Association SE

02-01-14 to 01-31-16

$ 27,000 PI

3. Short Term Training of Health Professional Schools NIH T35 HL007489-31

09-01-13 to 08-31-18

$ 480,420 PI

TOTAL ACTIVE

$1,757,420

TRAINING GRANT TITLE COMPLETED AGENCY DATES TOTAL COSTS

GS ROLE

1. Short Term Training of Health Professional Schools NIH T35 HL007489-28

04-01-08 to 08-31-12

$ 516,870 PI

2. Molecular Biology and Gene Therapy in Burns And Trauma

NIH T32 GM08721-04

07-01-01 to 06-30-04

$ 326,917 Mentor Co-Invest

3. Molecular Biology and Gene Therapy in Burns And Trauma

NIH T32-GM08721-08

07-01-04 to 06-30-09

$ 604,643 Mentor Co-Invest

4. Research Training in Vision Science NIH T32 EY07132-12

09-30-00 to 10-01-04

$ 412,904 Mentor Co-Invest

5. Research Training in Vision Science NIH T32 EY07132-12

09-30-04 to 10-01-09

$ 988,890 Mentor Co-Invest

6. Vision Research Center NIH P30 EY08571-08

04-01-00 to 03-31-04

$ 2,452,674 Co-Invest

7. Vision Research Center NIH P30 EY08571-13

04-01-04 to 03-31-09

$ 2,882,518 Co-Invest

8. Mechanisms of Shear Regulated Vein Graft Remodeling

NIH K08 HL076453-01

04-01-04 to 06-30-09

$ 616,831 Mentor to S. Berceli

9. Research in Cardiovascular Diseases American Heart Association SE

02-01-12 to 01-31-14

$ 27,000 PI

Total Completed

$8,829,247

TOTAL TRAINING GRANTS ACTIVE + COMPLETED

$ 10,586,667

CLASS ROOM INSTRUCTION AT THE UNIVERSITY OF LOUISVILLE

1.1. 1. Medical Biochemistry 600. Presented lectures, from 1979 to 1989, on water, pH, amino acids, protein structure and

Page 30 of 38

purification, collagen, elastin, contractile proteins, blood clotting, antibodies, simple carbohydrates, proteoglycans, glycoproteins, and endocrinology. Course director, first quarter, 1984.

2. Biochemical Endocrinology 670. Initiated this new graduate course required for Ph.D. students in Biochemistry in

1980. Presented lectures in 1980, 81, 82, 83 on pituitary hormones including gonadotrophins, prolactin, growth hormone, ACTH, and on endorphins, growth factors, oncogenes, catecholamines, insulin, glucagon, gastrointestinal hormones and angiotensin. In 1984 this course was enlarged to include topics of advanced reproductive endocrinology including placental hormone production, immune system hormones, and biochemical aspects of in vitro fertilization/embryo transfer. Course director 1980-1988.

3. Biochemical Methods 612. Presented lectures from 1979 to 1988 on radioisotopic techniques, and on cell and tissue

culture techniques. 4. Special Topics in Biochemistry 603. Presented lectures in 1981, 82 on glycoprotein biosynthesis, and intracellular

compartmentalization of proteins. 5. Board Review Course BRC-84. Presented review lectures on protein chemistry, hemoglobin, blood clotting and

enzymology for sophomore students taking National Boards, Part I.

RESEARCH MENTORING AT UNIVERSITY OF LOUISVILLE 1. Primary Advisor Year Current Position

1. Susan Fitzpatrick, M.S. 1980 Faculty member, Baylor University 2. William King, M.S. 1986 Resident in Surgery, University of Louisville 3. Philip Woost, Ph.D. 1987 Postdoctoral Associate, Case Western University 4. Glenn Franklin, M.S. 1988 Resident in Surgery, Medical College of Georgia 5. John Henry, Ph.D. 1989 Boston Biomedical Research Institute

2. Dissertation or Thesis Committees Year Department

1. Ronald Wiehle, Ph.D. 1983 Biochemistry 2. Georgette Howard, Ph.D. 1986 Biochemistry 3. James Miller, Ph.D. 1987 Biochemistry 4. Steve Wagner, Ph.D. 1986 Biochemistry 5. Raymond Weckman, M.S. 1983 Anatomy 6. Melinda Brown, Ph.D., MD 1984 Anatomy 7. Nancy Muma, Ph.D. 1985 Pharmacology 8. Deanne Benovitz, Ph.D. 1986 Chemistry 9. Douglas Sherman, Ph.D. 1988 Chemistry 10. Patricia Drury, M.S. 1988 Anatomy

3. Postdoctoral Associates Year Current Position

1. Michael P. LaChance, MD, Ph.D. 1982 Private practice 2. Gerry O'Daniel, MD 1986 Private practice 3. Nancy Muma, PhD 1985 Pharmaceutical industry 4. Mindy Brown, Ph.D., MD 1985 Private practice 5. Elaine Sonnenfeld, Ph.D. 1986 Pharmaceutical industry 6. Mark Petitjean, MD 1987 Private practice 7. Krzysztof Darlak, Ph.D. 1987-88 Peptides International, Inc. 8. Shawn Jones, M.D. 1987-88 Private practice

4. Research Assistant Professor Dr. Ming Ling, 1983, currently Chairman of Biochemistry, National University of Taiwan 5. Medical/Dental Students: Summer Research Program or Research Elective Larry Williams, M.D. 1983 Lisa Cipolla, M.D. 1987 Joseph Metz, DMD 1983 Angela Duff, M.D. 1987 Mark Lambertus, M.D. 1984 Allan Whitehouse, M.D. 1987 Jerry Schrodt, M.D. 1985 Robert Mitchell, M.D. 1988 Joseph Brightwell, M.D. 1985 Jerry Davis, M.D. 1988 Steve Riddle, M.D. 1986 E. Brit Brockman, M.D. 1988

Page 31 of 38

John Fassio, M.D. 1989 6. Undergraduate Summer Research Scholars 1. Jamie Monroe 1983 2. Mary Lorenz 1980 3. Melissa Roberts 1987 7. Awards Recognizing Research of Graduate or Medical Students

Philip Woost Yankeelov Award for Outstanding Ph.D. student in Biochemistry, 1984; First Place, Student Research Day Competition, 1983; Graduate and Professional Student Research Awards, 1982 and 1983; American Cancer Society Institutional Award, 1983-84

Lisa Cipolla Second Place, Student Research Day Competition, 1984 Angela Duff Honorable Mention, Student Research Day Competition, 1984 Steve Riddle Second Place, Student Research Day Competition, 1983 Jerry Schrodt Honorable Mention, Student Research Day Competition, 1982

CLASSROOM INSTRUCTION AT THE UNIVERSITY OF FLORIDA

1. DEN 6128 Principles of Immunology (required course). Teach three lectures on the principles of wound healing to second year dental students from 1999- to present.

2. DEN 6880 Principles of Craniofacial Biology and Emerging Therapies (required course). Teach two lectures to

dental students that review molecular and cellular regulation of oral wound healing and emerging technologies from 2013 to present.

3. GMS 6001 Fundamentals in Biomedical Science (required course). Taught two lectures and two Grand Rounds on the components of the extracellular matrix in 1998-2009, served as Course Director Section 4 from 2005 to 2009.

4. BMS 6204 Biochemistry and Molecular Biology of Health and Disease (required course). Taught ten clinical correlation discussions for a unit lab of freshman medical students from 1991 to 2008.

5. GM 6161 Oral Biology II (required course). Taught one lecture on general principles of wound healing to oral biology graduate students and post-graduate dental fellows from 1995 to 1999.

6. DEN 6657 Introduction to Advanced Periodontology (required course). Taught three lectures on the principles of wound healing to oral post-graduate periodontology fellows from 1996 to 1999.

7. GMS 6416 Human Endocrinology and Anatomy of Reproduction (required course). Taught one lecture in this course that was initiated in 2007. This course was required for PhD students in the new major of reproductive endocrinology in the College of Veterinary Medicine.

8. NUR 3225 Nursing Care Management (required course). Taught one lecture to junior students on Wound Care in 2010.

9. GMS 6709 Topics in Vision (elective course) Taught one lecture to PhD students in the Vision Training Grant program on corneal structure and wound healing Fall 2011.

10. IDH 3931 Molecular Regulation on Wound Healing – From Bench to Bedside Translation (Honors College elective course). This new course was open to undergraduate students who were admitted to the Honors College. It covers basic biochemistry and cell biology of normal wound healing and imbalances that lead to excessive healing (fibrosis) and failure to heal (chronic wounds). Course director and presented 11 lectures, Spring 2015.

INTERNATIONAL CLASSROOM INSTRUCTION - CARDIFF UNIVERSITY 1. ME3015 Biology of Wound Healing (required course) Taught one to two lectures on normal and pathological

phases of skin wound healing to Masters of Science students in the Wound Healing and Tissue Repair graduate program – 2010 to present.

Page 32 of 38

RESEARCH MENTORING AT UNIVERSITY OF FLORIDA 1. Primary Advisor Area Degree Year

1. Chin (Vivian) Chen, B.S. Molecular Genetics M.S. 1998 2. Cui Chen, B.S. Cell Biology M.S. 1999 3. Glenn Ladwig, B.S., L.L.D. Molecular Genetics M.S. 2000 4. Lakshmi Balasubramanian, MBBS Molecular Genetics M.S. 2000 5. Santosh Gowda, M.B.B.S. Molecular Genetics M.S. 2002 6. Heather Paddock, M.D. Clinical Investigation M.S. 2002 7. Tim Blalock, B.S. Biochemistry Ph.D. 2003 8. Suresha Rajaguru, M.B.B.S. Molecular Genetics M.S. 2004 9. Heejung Yang, B.S. Molecular Genetics M.S. 2005 10. Dan Gibson, B.S.E. Molecular Genetics M.S. 2006 11. Jia Liu, B.S. Molecular Genetics PhD 2006 12. Don McCurry, B.S., P.T. Molecular Genetics M.S. 2007 13. Qingping Yang, B.S. Molecular Genetics M.S. 2008 14. Kathy Mayor-Lynn, M.D. Clinical Investigation M.S. 2008 15. Afifa Hamad, B.S. Molecular Genetics M.S. 2010 16. Sriniwas Sriram, B.E. Biomedical Engineering M.E. 2011 17. Dan Gibson, B.S.E., M.S. Molecular Genetics Ph.D. 2011 18. Paulette Robinson, B.S. Molecular Genetics Ph.D. 2012 19. Sriniwas Sriram, M.E. Biomedical Engineering Ph.D. 2013

2. M.S. & Ph.D. Graduate Committees Department Degree Year 1. James Talton, M.S. Material Sciences M.S. 1995 2. Shawn P. Macauley, Ph.D. Oral Biology Ph.D. 1996 3. Susan Rassmussen, Ph.D. Chemistry/Biochemistry Ph.D. 1997 4. Robert Habda, M.S. Material Sciences M.S. 1997 5. Ho-Seng Kim, Ph.D. Pharmaceutical Sciences Ph.D. 1998 6. Adriana Da Silveira, Ph.D. Oral Biology Ph.D. 1998 7. Sharon Wall, Ph.D. Neuroscience Ph.D. 1998 8. James Talton, Ph.D. Pharmaceutics Ph.D. 1999 9. Toby Ferguson, Ph.D., M.D. Neuroscience Ph.D. 2000 10. Harveen Dhillon, Ph.D. Neuroscience Ph.D. 2000 11. Larry Land, Ph.D. Chemistry Ph.D. 2001 12. Sonja Parisek, M.S. Animal Sciences M.S. 2001 13. Jing Li, M.S. Molecular Genetics M.S. 2003 14. Mihai Ciustea, B.S. Chemistry Ph.D. 2003 15. Kareem Burney, B.E. Biomedical Engineering M.S. 2003 16. Taili Thula, B.E. Biomedical Engineering M.S. 2003 17. Franck Ollivier, DVM Animal Sciences Ph.D. 2004 18. Rong Xiu, B.S. Molecular Genetics M.S. 2004 19. Beverly Childress, B.S.N. Nursing Ph.D. 2004 20. Andria Desovousges, B.S. Animal Sciences M.S. 2005 21. Melissa Williams, B.S. Molecular Genetics M.S. 2006 22. Shannon Haire, B.S. Molecular Genetics Ph.D. 2006 23. John Azeke, B.E. Biomedical Engineering Ph.D. 2006 24. Olajompo Moloye, B.E. Biomedical Engineering Ph.D. 2006 25. Taili Thula, B.E., M.S.E. Biomedical Engineering Ph.D. 2006 26. William Brazelle, B.S. Pharmacology Ph.D. 2006 27. Jinah Kim, B.S. Chemical Engineering Ph.D. 2006 28. John Alexander, B.S. Molecular Genetics Ph.D. 2007 29. Sharon Norton, B.S. Molecular Genetics M.S. 2007 30. Stacy Porvasnik, B.S. Molecular Genetics M.S. 2007 31. Kyumee Yo, B.S. Molecular Genetics M.S. 2007 32. Matthew Buzzeo, B.S. Molecular Genetics M.S. 2007 33. Azedah Shirazian, B.S. Molecular Genetics M.S. 2007 34. Julia Huang, B.S. Molecular Genetics M.S. 2007 35. Jennifer Rainho, B.S. Molecular Genetics M.S. 2009 36. Eungi Lee, B.S. Molecular Genetics M.S. 2009 37. Pranati Kumar, B.S. Molecular Genetics M.S. 2009

Page 33 of 38

38. Steve Werden, B.S. Molecular Genetics Ph.D. 2009 39. Jessie Kay, B.S. Molecular Genetics Ph.D. 2009 40. Patrick Kerns, B.S. Physiology M.S. 2010 41. Dustin Lang, B.S. Molecular Genetics M.S. 2010 42. Lee Ferguson, B.S. Molecular Genetics Ph.D. 2010 43. Tara Washington, B.E. Biomedical Engineering Ph.D. 2010 44. Rachael Watson, B.S. Molecular Genetics Ph.D. 2010 45. Cheng-Chun Peng, B.S.E. Chemical Engineering Ph.D. 2011 46. Pei-Yu Chung Biomaterials Engineering Ph.D. 2011 47. Meghan O’Donoghue Chemistry Ph.D. 2012 48. Mingxu You Chemistry Ph.D. 2012 49. Emir Yasun Chemistry Ph.D. 2013 50. Da Han Chemistry Ph.D. 2013 51. Guizhi Zhu Chemistry Ph.D. 2013 52. Elizabeth Jimenez Chemistry Ph.D. 2013 53. Cuichen Sam Wu Chemistry Ph.D. 2015 54. Cody Jackson Molecular Genetics M.S. 2015 55. Ben Goldberg Biomedical Engineering M.S. 2015 56. Liqin Zhang Chemistry Ph.D. 2016 57. Laura Proietto Veterinary Medicine M.S. 2016 58. Lily Svete Biomedical Sciences M.S. 2016 59. Stephanie Lamb Molecular Genetics M.S. 2016 60. Carole Champanhac Chemistry Ph.D. 2016 61. Sena Cansiz Chemistry Ph.D. 2016 62. Ismail Ocosy Chemistry Ph.D. candidate 63. Huseyin Erdal Chemistry Ph.D. candidate 64. Shuo Wan Chemistry Ph.D. candidate 65. Cody Smith Physiology Veterinary Med Ph.D. candidate 66. William Berkowski Veterinary Medicine M.S. candidate 67. Diego Esparza-Duran Clinical and Health Psychology Ph.D. candidate 68. Yian Guo Chemistry Ph.D. candidate 69. Weijia Hou Chemistry Ph.D. candidate 70. Kimberly Stewart Chemistry Ph.D. candidate

3. External examiner Rijian Wang, Ph.D. University of Alberta, Edmonton, Canada Department of Surgery, 1997 Patricia Nadworny, Ph.D. University of Alberta, Edmonton Canada Department of Materials Engineering 2009 4. Residents Research Projects Ophthalmology Year Surgery Year Otolaryngology Year Scott Strelow, M.D. 1989 Scott Rotatori, M.D. 1989 Jonathan King, M.D. 1990 Natalie Kerr, M.D. 1990 Neil Bennett, M.D. 1990 Agnes Nall, M.D. 1992 John Barletta, M.D. 1992 Hugh Sims, M.D. 1992 Karen Oxford, M.D. 1992 Ob/Gyn Year Warren Stiles, M.D. 1992

Kelly Hutcheson, M.D. 1995 Greg Locksmith 2000 Peyton Colvin, M.D. 1993 Mario Forcina, M.D. 1996 Mike Avidono, M.D. 1993 Guy Angella, M.D. 1997 Dermatology Year Cheryl Cotter, M.D. 1993 John Gross, M.D. 2002 David Weinstein 2011 Jason Wilmoth, M.D. 1998 Alex Blandford, M.D. 2015 Orthopaedics Year Wesley Frevert, M.D. 2015 5. Visiting Faculty and Graduate Students

Cong (Nancy) Mao PhD student Sept 2012 - Aug 2013 South China University of Technology, Guangzhou, PRC Guo-Li Yin, PhD Assistant Prof July 2013 – July 2014 Institute of Cell Biology and Genetics, Zhejiang University, Hangzhou, China

6. Medical Student Research Program

Lee Jung 1990 Kyle Balch 1992 David Kimble 1992 Robert Stiff 1994

Jeff Brink 1990 Ken Haft 1992 Tuan Nguyen 1993 Missy Block 1996

Steve Tebes 1997 Angie Prevatt 2003 Siva Radhakrishnan 2004 Bret Baskovich 2009

Page 34 of 38

Josh Vickers 2009 Sara Rodrequez 2010

Sang Gyou Rho 2011 Luther St. James 2012

Nicole Melanson 2013

7. Post-Doctoral Associates Years Current Position

1. Sally MacKay, Ph.D. 1991-4 Assistant Professor, Dept Surgery, Univ. Florida 2. Roy Tarnuzzer, Ph.D. 1993-6 Assistant Professor, Dept Medicine, Univ. Florida 3. Xiao-ou Ren, M.D., Ph.D. 1996-8 Post-Doctoral Associate, University of North Carolina 4. Rong Yuan, M.D., Ph.D. 2000-1 Senior Staff Scientist, Cold Springs Harbor Labs 5. John Azeke, PhD. 2007-8 Staff Scientist, Institute for Chemical Defense US Army 6. Jompo Moloye, Ph.D. 2007-8 Staff Scientist, Ethicon Inc., Johnson & Johnson Co. 7. Pricilla Phillips, Ph.D. 2006-8 Assistant Professor, Dept Microbiology, Kirksville College Osteopathic Medicine 8. Mick Popp, Ph.D. 2009-10 Senior Project Manager, Regeneration Technology, Inc. 9. Parag Parekh, Ph.D. 2009-10 Post-doctoral Associate University of Houston 10. Pei-yu Chung, Ph.D. 2011-13 Project Scientist, Vistakon, Jacksonville, FL 11. Daniel Gibson, Ph.D. 2012-14 Research Assistant Professor, Institute for Wound Research, UF 12. Xiaodi Feng, Ph.D. 2014-15 Post-doctoral Associate, University of Florida

8. High School Students and Science Teachers

1. Tuan Lui 1995 Summer Science Training Program, Miami High School, Miami, Florida 2. David Mills 1996 Summer Science Training Program, Deltona High School, Deltona, Florida 3. Lan Van 1997 Summer Science Training Program, Miami High School, Miami, Florida

4. Dan Foster 1997 Science Teacher Research Training, Powell High School, Knoxville, TN 5. Sun Hee Rim 1998 Summer Science Training Program, Hillsborough High School, Hillsborough, FL 6. Jessica Prenatt 1998 Science Teacher Research Training, Lovejoy Middle School, Lovejoy, GA 7. Pamela Smith 1998 Science Teacher Research Training, Johnson Middle School, Jacksonville, FL 8. Albert Huang 1999 Summer Science Training Program, Spruce Creek High School, Ormond Beach, FL 9. Vandana Gupte 1999 Science Teacher Research Training, Hedgesville High School, Hedgesville, WV 10. Alicia Wright 2000 Summer Science Training Program Vanguard High School, Ocala, Florida 11. Mindy Pearson 2000 Science Teacher Research Training, Rodgers Middle School, Riverview, Florida 12. Vikram Palker 2001 Summer Science Training Program, Anderson High School, Ft. Lauderdale, Florida 13. Cynthia Vasques 2002 Summer Science Training Program, Boca Raton High School, Florida 14. David Reyes 2003 Summer Science Training Program, Blanche Ely High School, Pompano Beach, FL 15. Craig Levoy 2004 Summer Science Training Program, Spruce Creek High School, Ormond Beach, FL 16. Philip Carlson 2004 Summer Science Training Program, Christopher Columbus High School, Miami, FL 17. Nima Khosravani 2005 Summer Science Training Program, Trinity Preparatory School, Winter Park, FL 18. Isabelle Dortonne 2006 Summer Science Training Program, North Miami Beach High School, FL 19. Ashwin Telukuntla 2007 Summer Science Training Program, St Stephen’s Episcopal H.S., Bradenton, FL 20. Sonia Chheda 2008 Summer Science Training Program, Hillsborough High School, Tampa, FL 21. Anne-ChristelleLarose, 2010 Summer Science Training Program, West Boca Raton High School, FL 22. Vishal Thumar 2011 Summer Science Training Program, Hillsborough High School, Tampa, FL 23. Stace Alcala 2012 Science Teacher Research Training, Mulberry Senior High School, Mulberry, FL 24. Amy Demins 2012 Science Teacher Research Training, Oviedo High School, Orlando, FL 25. Noemi Reyes 2013 Summer Science Training Program, Immokalee High School, Immokalee, FL 26. Claudia Singkornrat 2013 Science Teacher Research Training, Pompano Beach High School, Pompano, FL 27. Allison Beer 2015 Summer Science Training Program, Marjorie Douglas High School, Parkland, FL 28. Rachel Geller 2016 Summer Science Training Program, Cypress Bay High School, Cypress Bay, FL

9. Senior Undergraduate Honors Research Projects

1. Eric Kohlbrenner 1998 Senior Honors Research 2. Juan Varela 1999 University Scholar Program 3. Sima Patel 1999 Senior Honors Research 4. Samer Patel 2000 Senior Honors Research 5. Kelly Brinsko 2000 University Scholars Program 6. Julia Burrows 2000 Senior Honors Research 7. Kavita Gandhi 2001 University Scholars Program 8. Brett Baschovitz 2003 Senior Honors Research 9. Vikarm Palker 2005 Senior Honors Research 10. Brad Hill 2006 University Scholars Program 11. Craig Levoy 2007 University Scholars Program 12. Ashley Ferrara 2007 Interdisciplinary Major Research

Page 35 of 38

13. Stephen Cooke 2008 University Scholars Program 14. Dilan Patel 2010 Senior Honors Research 1 of 2 Outstanding Four Year Scholars commencement 15. David Kerekes 2012 Senior Honors Research 16. Peter Lee 2013 Undergraduate Research – College of Health Professions, Physical Therapy 17. Haley Klein 2013 Undergraduate Research – College of Health Professions, Physical Therapy 18. Emily Hartlage 2013 Undergraduate Research – College of A&S, Microbiology and Cell Science 19. Anatasiya Mitryukhina 2013 Undergraduate Research – College of Nursing 20. Alexander Zirulnik 2014 Undergraduate Research – College of A&S, Microbiology and Cell Science 21. Alessandra DiMare 2015 Undergraduate Research – College of A&S, Microbiology and Cell Science 22. Steffan Sasson 2016 Undergraduate Research – College of A&S, Biochemistry

SERVICE AT THE UNIVERSITY OF LOUISVILLE Committee Year 1. Medical Student Grievance Committee Member 1981-1986, Chair, 1983-86 2. Freshman Medical Student Unit Laboratory Advisor Member 1982-84 3. J. G. Brown Cancer Center, Oncology Seminar Committee Chair, 1983-84 4. J. G. Brown Cancer Center, Education Committee 1982 5. Medical Student Promotions Committee 1984 6. President's Distinguished Teaching Award, Medical Center Nomination Committee, 1984-86 7. Pharmacology Graduate Program Review Committee Chair, 1985 Biochemistry Department 1. Search Committee for Assistant Professor Positions in Biochemistry, 1981, 82, 86, 87 (Chair) 2. Director of Undergraduate Summer Research Program, 1980 3. Graduate Committee, 1979-87 4. Personnel Committee, 1984, 86, 87 5. Research Committee, 1984, 86, 87 6. Co-organizer of Research Conference, "Biochemistry of Ligand-Protein Interaction" 1979 Associate Appointments 1. Department of Ophthalmology, 1984 2. Department of Obstetrics and Gynecology, 1984 3. Department of Surgery, 1984

SERVICE AT THE UNIVERSITY OF FLORIDA University of Florida General Committees Dates 1. University of Florida Faculty Senate 1991-1992 2. University Academic Freedom, Tenure, Professional Relations and Standards Committee 2004-2007 3. Joint Faculty Senate and Presidential Task Force on Implementing Shared Governance 2005 College of Medicine General Committees Dates 1. Clinical Research Center, Review Committee 1989-1991 2. Search committee, Chair, Department of Biochemistry 1995 3. Faculty Council, Vice President, School of Medicine 1995-1996 4. Basic Science Reorganization Faculty Advisory Committee 1995 5. Search committee, Assistant Professor, Structural Biologist, Department of Ophthalmology 1995 6. Search committee, Assistant Research Scientist, Department of Otolaryngology 1995 7. Faculty Research Advisory Board 1996-1999 8. Search committee, Assistant Professor, Department of Physiology 1997 9. Faculty Council, President 1997-1998 10. College of Medicine Sexual Harassment Committee 2000-2003 11. Medical Student Admission Committee 2002-2007 12. Faculty Council Secretary 2003-2006 13. College of Medicine Associate Professor Tenure and Promotion Committee 2003-2005 14. Search committee, Chief of Plastic Surgery, Department of Surgery 2004 15. Search committee, Chief of Dermatology Division, Department of Medicine 2004 16. College of Medicine Constitution Drafting Committee 2006 17. Search committee, Chair of Obstetrics and Gynecology 2007 18. Search committee, Chair of Dermatology Department 2007, 08, 09, 10

Page 36 of 38

19. Search committee, Chief of Plastic Surgery, Department of Surgery 2010 20. College of Medicine, LCME Accreditation Committee on Research 2014-15 21. Search committee, Chief of Dermatology Division, Department of Medicine 2017 Department of Obstetrics and Gynecology Committees/Service Dates 1. Faculty Council, Ob/Gyn Department Representative, School of Medicine 1994-1995 2. Research Leadership Committee, Dept ObGyn representative 2012-2016 Adjunct Faculty Appointments (all still active) 1. Department of Biochemistry, 1992 4. Department of Oral Biology, 1995 2. Department of Medicine, 1992 5. Department of Veterinary Medicine, 2015 3. Department of Ophthalmology, 1989

SERVICE FOR SCIENTIFIC ORGANIZATIONS Scientific Organizations 1. Program Planning Committee, Association for Research in Vision and Ophthalmology, Cornea, 1988-1991 2. Board of Directors, Wound Healing Society, 1995-97. 3. Program Planning Committee, 2nd Joint Meeting of Wound Healing Society and European Tissue Repair Society,

Boston MA, May, 1996. 4. President-Elect of Wound Healing Society, 1997-98 5. President of Wound Healing Society, 1999-01 6. Past President of Wound Healing Society, 2000-2002 7. Chair, Wound Bed Preparation Advisory Panel, 2003-5 8. National Pressure Ulcer Advisory Panel, Member 2007-2010 9. 4th World Union Wound Healing Societies Meeting Organization Committee, Research Track, Toronto CA, 2007-08 10. 5th World Union Wound Healing Societies Meeting, Executive Committee, 2009-11, Yokohama, Japan 2012

Ad Hoc Reviewer Journals (approximate number of manuscripts reviewed) 1. American Journal of Surgery (5) 2. American Journal of Physiology (2) 3. American Journal of Pathology (9) 4. Archives of Dermatology 5. Biochemica et Biophysica Acta (2) 6. Breast Cancer Research and Treatment (3) 7. British Journal of Ophthalmology (2) 8. British Journal of Surgery (1) 9. Cancer Research (3) 10. Cell and Molecular Biology (1) 11. Cell Signaling (1) 12. Comparative Biochemistry and Physiology (1) 13. Current Eye Research (10) 14. Cutaneous Ocular Toxicology (6) 15. Diabetologia (3) 16. Diabetes Care (2) 17. Endocrinology (3) 18. Experimental Eye Research (50) 19. Federation Proceedings (3) 20. Infection and Immunity (1) 21. Investigative Ophthalmology & Visual Science (38) 22. International Wound Journal (10)

23. Journal of Biological Chemistry (5) 24. Journal of Clinical Investigation (3) 25. Journal of Investigative Dermatology (9) 26. Journal of Histochemistry and Cytochemistry (1) 27. Journal of Surgical Research (3) 28. Journal of Interferon Research (1) 29. Journal of Vascular Surgery (1) 30. Lancet (1) 31. Life Sciences (1) 32. Molecular and Cellular Biochemistry (1) 33. Molecular Pharmacology (2) 34. Molecular Vision (2) 35. Nature (1) 36. Proceedings of National Academy of Science (4) 37. Regulatory Peptides (2) 38. Science (2) 39. Science Technology (1) 40. Society for Experimental Biology and Medicine (1) 41. Tear and Ocular Surface (1) 42. Wound Repair and Regeneration (32) 43. Wounds International (15)

Editorial Boards 1. Experimental Eye Research, Executive Editor, 1997 – 2008 2. Current Eye Research, Editorial Board, 2001 – 2008 3. Cutaneous and Ocular Toxicology, Editorial Board, 2001 – present 4. Wound Practice & Research, Australian Wound Management Association, Editorial Board, 2002 – present 5. Wound Repair and Regeneration, Editorial Board, 2002 – present 6. International Wound Journal, Editorial Board, 2003 – present 7. International Journal of Lower Extremity Ulcers, Editorial Board, 2004 – 2007

Page 37 of 38

8. Wounds International, Editorial Board, 2009 – present

Reviewer for Grant Agencies 1. Kentucky Heart Association 1985 2. National Science Foundation 1986 3. NIH Vision 1 Study Section Ad Hoc member 1988 4. NIH Institute of Arthritis Musculoskeletal Disease Ad Hoc member 1991 5. NIH Clinical Sciences 1 Study Section Ad Hoc member 1992 6. Tobacco and Health Research 1988 7. W. W. Smith Charitable Trust 1992 8. Wellcome Trust, Ltd 1993 9. NIH Arthritis, Connective Tissue and Skin Study Section Ad Hoc member April, 2004, October 2004. 10. NIH Special Emphasis Study Section GGG-J, March 16, 17, 2005. 11. U.S. Defense Threat Reduction Agency, Program Review, April 18, 2005. 12. NIH Special Emphasis Study Section ZRG1 MOSS-C, March 4, 2006 13. NIH Special Emphasis Study Section ZRG1 MOSS-C, March 5, 2007 14. NIH Anterior Eye Disease Study Section, June 1-2, 2009 15. NIH Anterior Eye Disease Study Section, February 11-12, 2010 16. Australian National Health and Medical Research Council, 2009 17. Qatar National Research Fund 2011-2013 18. Medical Research Council (UK) 2012 19. NIH COUNTERACT Special Emphasis review panel July 2, 2012 20. NIH National Institute Deafness and Other Communication Disorders, February 14, 2013 21. South Plains Foundation, July 2013 22. Department of Defense, Technology/Therapeutic Development Award, Vision Research Program, February 2016 23. Natural Sciences and Engineering Research Council of Canada, 2017

Professional Consulting Services – Compensated 1. 3M, Ltd 2. AbbVie, Inc. 3. Acelity, Inc. 4. Anamed, Inc. 5. Arriva Pharmaceuticals 6. Auxano Diagnostics, LLC 7. Biosara, Corp 8. Biomonde 9. Cardinal Health 10. Celleration, Inc. 11. Chiron, Inc 12. Chiron Vision, Inc. 13. Coloplast Wound Care 14. Derma Sciences 15. Ethicon, Inc. 16. Exoxemis

17. Fibrogen, Inc. 18. Glycomed, Inc. 19. Greystone Medical, Inc. 20. Health Point, Inc. 21. Hollister Wound Care, Inc. 22. Intelligent Ventures, LLC 23. Kinetic Concepts, Inc. 24. Life Cell, Inc 25. Lohmann & Rauscher, Inc. 26. Medline, Inc. 27. Medtronic, Inc 28. Mölnlycke, Inc. 29. Nanotherapeutics, Inc. 30. Next Science, LLP 31. Novagen, Inc. 32. Nuron Biotech, Inc.

33. Oncogen, Inc. 34. Organogenesis, Inc. 35. Quick Med, Inc. 36. Renovo, Ltd. 37. Santen, Inc. 38. Sanofi-Aventis 39. Smith & Nephew 40. Suwelack Skin & Health Care, AG 41. Thermogenesis, Inc. 42. Thermalin Diabetes, LLC 43. U.S. Biomaterials 44. Vistakon, Inc. 45. Xomed, LLC

Scientific and Clinical Advisory Boards 1. Renovo, Ltd. 2003 – 2007 2. Greystone Pharmaceuticals, Inc. 2004 – 2009 3. Auxano Diagnostics, L.L.P. 2006 – 2012 4. Excaliard Pharmaceuticals, Inc. 2007 – 2011 (purchased by Pfizer, November 2011) 5. Nanotherapeutics, Inc. 2008 – 2011 6. Kinetic Concepts, Inc. 2008 – 2013 7. Biosara, Corp. 2010 – 2013 8. QuickMed Technologies, Inc. 1996 – present 9. Medline Advance Skin & Wound Care 2009 – present 10. Suwelack, MedSkin Solutions, AG 2010 – present 11. Hollister Wound Care 2012 – present 12. BioMonde 2015 – present

Clinical Trials

Page 38 of 38

1. Accelerated Corneal Epithelial Wound Healing using Human Epidermal Growth Factor after Corneal Transplantation. June 1, 1984.

2. Use of Human Epidermal Growth Factor in Severe Corneal Epithelial Defects. June 10, 1984. 3. Use of Biosynthetic Human Epidermal Growth Factor for Accelerating Epidermal Healing of Split-Thickness Donor-

Sites of Burn Patients. June 2, 1986. 4. Treatment of Diabetic Foot Ulcers with a Protease Inhibitor, Doxycycline, October 1, 2001. 5. Treatment of Diabetic Foot Ulcers with an Adenovirus Vector expressing PDGF, August, 2002. 6. Treatment of Chronic Diabetic Foot Ulcers with Topical Doxycycline, Phase II, October 2008 7. Treatment of Dehisced Acute Trauma Wounds with Topical NanoDox, February, 2012 8. ManukaMed Honey Dressings on Bacterial Biofilms in Chronic Wounds, July 2013 9. VAC + Microcyn Instillation Effects on Biofilms in Chronic Skin Wounds, February 2014 10. Effect of Iodosorb on Biofilms in Chronic Diabetic Foot Ulcers, March 2014 11. Quantifying Biofilms on Removed Hemodialysis Catheters Cleaned with Neutrolin, February, 2016