Cubis II: Your Balance, Your Way

Cubis® II: Your Balance, Your Way

Connectivity

Climate Monitoring

Workflow Integration with QApps

Cubis® II: The New Generation of Modular Premium Balances

For scientists in R&D or analytical laboratories needing the most reliable lab weighing results, the Cubis® II platform from Sartorius is a completely configurable, high-performance portfolio of both lab weighing hardware and software. The Cubis® II will align with your unique demands and compliance requirements to help maximize your operational efficiency and experimental outcomes.

The Cubis® II platform is the only laboratory balance with fully customizable hardware, software, and connectivity. It offers modern user interfaces, pharmaceutical and GxP compliance, including data handling, data integrity and connectivity, ergonomic sample handling, easy process integration, and unlimited communication at the highest level of accuracy and precision.

Find out moreFor more information, please visit

www.sartorius.com/cubis-ii

Pharma Compliance

Automatic Motorized Leveling

Integrated Ionizer

Customizable Modularity

• Thousands of hardware and software configurations supporting your personal preferences.

• Thematically structured software packages for your optimized workflows.

• Seamless connectivity to diverse laboratory information systems without the need of additional software.

• Long-term flexibility guarantees adaptation of software and accesories to evolving regulatory and laboratory needs.

Confident Compliance*

• Full data integrity following ALCOA+ principles.

• Complete traceability via advanced audit trail and reporting function for efficient reviews.

• Submission-ready data with remote data selection on web browser.

• User management including centralized password management support („single-sign-on“ via LDAP), high security password configuration, login rules.

• Electronic signature in com-pliance with 21 CFR Part 11.

Intelligence by Design

• Build-in applications guide you through your workflows.

• Fast and easy leveling guaranteed with automatic, motorized leveling function.

• Innovative draft shield tech-nology with gesture sensor and memory functions.

• Climate sensor for environmental monitoring.

• Built-in ionizer for automatic electrostatic elimination.

• Status Center for user notifications and alerts*.

• Ultramicro– and micro balances with innovative technology for top-edge performance.

Trusted Results

• Leading Performance• High Speed Accuracy• Error-Free Operations• Full End-to-End

Data Integrity• Reliable Support

*available with the MCA interface



Customizable Modularity – Thousands of Configurations

In 2009, Sartorius offered the first modular balance with the Cubis®, and today continues that tradition by offering the Cubis® II, the first lab balance series featuring a completely modular design:

Weighing Modules

Choose from a range of 45 different weighing modules that best fit your preferences.

Draft Shields

Choose from 7 different options, depending on your balance type – each with unique features to support maximal balance performance and user-centric design.

Display

Choose between advanced and essential user interface, based on your weighing applications and requirements.

Software

With up to 60 optional software applications clustered into QApp packages, and with continuous software development, we support your workflows now and in the future.

Ultra-Micro & Micro Balances

• Max. capacity between 2.1 g and 10.1 g | scale interval with a range of 0.1 μg to 1 μg.

• Automatic, motorized, round, glass draft shield with learning capability, illumination and integrated motion sensor.

• Manual stainless steel draft shield for filter weighing applications.

Semi-Micro & Analytical Balances

• Max. capacity between 120 g and 520 g | scale interval with a range of 0.01 mg to 0.1 mg.

• Automatic glass draft shield with or without integrated ionizer to eliminate interfering electrostatic charges on samples and sample containers.

• Manual glass draft shield with smooth-action doors.

Precision Balances

• Max. capacity between 320 g and 14,200 g | scale interval with a range of 1 mg to 100 mg.

• Easy to use manual glass draft shield.

• Removable flat stainless steel draft shield frame (not shown in the picture).

MCE Essential User Interface

Large, high-contrast touch display with factory-installed essential weighing applications for easy operation.

MCA Advanced User Interface

Large 7“ color touch display including touch, scroll, swipe functionality with factory- installed essential weighing applications and diverse QApp Packages for optional software extension.

Software Options

Choose between different packages to fulfill your demands. Each package contains powerful applications or functions to enhance and individualize your balance for your workflows.

• QApp Package Pharma• QApp Package Advanced

Applications• QApp Package Utilities• QApp Package Connectivity• All Inclusive QApp Package

(with new orders only)

High-Capacity Balances

• Max. capacity between 11200 g and 70,200 g | scale interval with a range of 100 mg to 1 g.



Intelligence by Design – Adaptable Lab Balance to Your Specific Needs

Ultra-Micro and Micro Balances

The world‘s first ultra-micro and micro balances with automatic motorized levelling, motion controlled and illuminated draft shield, and titanium inner parts. Weighing ranges from 0.1 μg to 10.1 g.

Gesture Control

The gesture sensor recognizes four gestures and can be positioned near the balance, directly in the flow of motion at your work space. It allows you to open and close the automatic draft shield, start the ionizer, or send a document to a device.

Onboard QApp Center

Choose your applications or individual balance functions from QApp packages clustered by different topics. License your selected package and integrate them into the tasks you can run on the balance.

Automatic, Motorized Leveling

Avoid the burdensome process of preparing your balance for use with the Cubis® II balance‘s quick and easy, motorized, auto-levelling function.

Built-in Ionizer for Electrostatic Elimination

Remove balance stabilization frustrations caused by electrostatic effects with the built-in ionizing technology of the Cubis® II balance.

Electrostatic charges on sam-ples and vessels are removed effectively, just by pressing one key or automatically when the draft shield door closes.

Climate Monitoring* , **

The climate sensor montiorsinfluencing variables of the environment and ensures that temperature, pressure, and humidity do not negatively affect your results.

Status Center Notifications*

The Status Center shows all information about your balance and environmental conditions, e.g. calibration, leveling, tem-perature, humidity, air pressure and service, centralized in a dashboard. In case of warnings or errors, you get detailed help and support.

* available with the MCA interface**available from July 2019



Confident Compliance –Complete Traceability

All data generated by the Cubis® II balance follow the key principles ALCOA (+), which defines data integrity standards and relates to GxPs. Therefore, the Cubis® II balance ensures safe and accurate data storage and supports all requirements for FDA directive 21 CFR part 11 and EU Annex 11 compliance.

The Cubis® II balance, with pharma package, contains all the technical controls to support compliance with common regulations. Full compliance can be achieved with additional procedural controls and systems for long-term data storage.

Backup

Cubis® II can automatically execute time-controlled actions for backup. The system is able to upload data on a file share or export the data to other systems. Archiving is easily possible and fully compliant.

Safe Data Transfer

An electronic record should be protected against any manipulation. The Cubis® II balance saves all files, together with a calculated MD5 check-sum which is stored in the audit trail files and additionally in a separate MD5 file.

Fully Compliant

Pharma

Time Synchronization

The Cubis® II balance supports automatic time synchronization via Network Time Protocol (NTP). An accurate time stamp is elemental for trustable records.

Electronic Signatures

In the Cubis® II balance, an electronic signature can be used to sign the final report for weighing processes. Based on a secure password, the combination of username and password is fully compliant with 21CFR.

Audit Trail & Alibi Memory

The Cubis® II balance’s audit trail is a tamper-protected time-stamped electronic logfile, that allows reconstruction of events related to the creation, modification, and | or deletion of records. The data can be displayed, filtered, and exported in an easy way.

User Management

The Cubis® II balance provides two options for complete user management with access control.

The local user management can be configured in accor-dance with your password policy.

The password rules for 21 CFR Part 11 compliance are easily implemented. Moreover, Cubis® II can be integrated in the company´s domain to allow single sign-on. In this case the company defined password rules are implemented auto-matically.

Additionally, the Cubis® II balance contains an “Alibi Memory”. The system automatically stores weighing data in a ring buffer.

TechnicalControls

Safe Data Transfer Time Synchronization

Backup

Audit Trail & Alibi Memory

Electronic Signatures

User Management



Configure Your Cubis® II Balance

*All weighing modules available with MCA or MCE display **Weighing module 32202P available with approvals S00 or S01 only***Software packages available for balances with MCA display only

Leveling Approval Draft shieldSoftware packages***

Balance type Weighing module*

auto-matic manual

S00, S01, CEU, CFR, CCN, OBR, OIN, OJP, ORU A E F I M R U O

QP1, QP2, QP3, QP4 or QP99

Ultramicro 2.7S

• • • • •

Micro10.6S, 6.6S, 3.6P

• • • • •

Semimicro225S, 225P, 125S, 125P

• • • • • •

Analytical 524S, 524P, 324S, 324P, 224S, 124S

• • • • • •

Precision 1 mg 5203S, 5203P, 3203S, 2203S, 2203P, 1203S, 623S, 623P, 323S

• • • • • • • •

Precision 10 mg5202S

• • • • • • • •

Precision 10 mg 8202S, 6202S, 6202P, 4202S, 2202S, 1202S

• • • •

Precision 10 mg 32202P**, 14202S, 14202P, 10202S

• • • •

Precision 100 mg5201S, 8201S

• • • •

Precision 100 mg 12201S

• • • •

High Capacity 70201S, 50201S, 36201S, 36201P, 20201S, 11201S, 70200S, 36200S

• • • •

- -

QApp Packages

…

User interface Weighing module Approval Draft shield

M C A 225S 2 S 0 0 I QP1 QP4 QP3

(Example)

Draft Shield DescriptionO Balance without draft shield

E Small glass draft shield

R Stainless steel draft shield frame

U Manual glass draft shield

A Motorized draft shield

I Motorized draft shield + Ionizer

M Motorized draft shield micro balances

F Filter draft shield micro balances

Approval DescriptionS00 Standard version worldwide

S01 Standard only metric units

CEU Verified version Europe (except FR)

CFR Verified Version France

CCN Verified Version China

OBR Verifiable Version Brazil

OIN Verifiable Version India

OJP Verifiable Version Japan

ORU Verifiable Version Russia

QApp Packages

QP1

QP2

QP3

QP4

QP99

The Pharma software application package contains applications concerning the topic compliance with pharmaceutical-relevant guidelines as 21 CFR Part 11 and USP 39, Chapter 41. The Pharma package includes applications such as user management, digital signatures, audit trail, USP minimum weight.

The Advanced software application package includes various complex weighing applications incl. evaluation. This includes applications used for density determination, percentage weighing, counting, backweighing, residual dirt analysis, residue on ignition, sieve analysis, filter weighing, checkweighing, formulation, averaging, etc.

The Utility software application package contains weighing applications and function extensions such as bootscreen, color scheme, free formula, fiber coarseness, diameter determination, air buyoancy correction, paper weight, statistics and printing of QR | bar codes.

The Connectivity software application package includes applications for data exchange, for example to Windows file server, FTPS, StarLims, etc.

The software application package All inclusive includes 4 different sub-packages for compliance (Pharma (QP1)), complex weighing applications (Advanced (QP2)), weighing applications and helpful tools (Utilities (QP3)) and connectors for data exchange (Connectivity (QP4)).

Pharma

Advanced

Utilities

Connectivity

User Interface DescriptionMCA Advanced user interface

MCE Essential user interface

Sales and Service ContactsFor further contacts, visit www.sartorius.com

www.sartorius.com

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mandy.brackley

SUPPLIER-ANZ

Cubis II: Your Balance, Your Way

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