Speaker Bio Anthony Carita is President of CTB Solutions and has 30 years of outsourcing experience within Pharmaceutical, CRO and Aerospace industries. CTB Solutions provides outsourcing consulting services and integrated business solutions for the Pharmaceutical, Biotech, and CRO industries and is the developer of SynSource™.

SynSource is an integrated lifecycle management tool that manages the following aspects of outsourcing:

• Provider identification • Standardized RFI and RFP development • Centralized proposal submission • Comparative proposal analysis • Facilitated negotiation • Contract development • Performance monitoring • Invoicing support tied to performance • Scope change management • Forecasting

Cost of Selection

� Case Study

SponsorTeam+ FTE+% Yr+1 Yr+2+on Rate Selection

Selection)process 30 20% 12,240))) 4)))))))))) 200$))))))) 2,448,000$)))))Cosulting)to)support)selection 1,100,000)))))))Average)cost)of)reponse)and)two)selection)meetings)by)each)Provider 750,000)))))))))))

Total+Hrs

3,548,000$+++++

Cost of Governance

� Case Study

Note: Assume travel, attendance, prep and follow-up is 14 hrs per person

Team% FTE%% Yr%1 Yr%2%on RateTotal%Hrs

Yr%1 Yr%2Sponsor%&%Strategic%Partner

Exec%Gov%(Q) 10 3% 560 560 350%%%%%%%%%Operational%Gov%(M%first%yr%Q%therafter) 30 8% 5,040%%%%% 1,680%%%%% 225%%%%%%%%%Program%Gov%(M%first%yr%Q%therafter) 40 8% 6720 2240 200%%%%%%%%%Functional%Gov%(M%first%yr%Q%therafter) 60 8% 10,080%%% 3,360%%%%% 225%%%%%%%%%Joint%Quality%Council%(M%first%yr%Q%therafter) 10 8% 1680 560 225%%%%%%%%%

196,000$%%%%%%%% 196,000$%%%%%%%%1,134,000%%%%%%% 378,000%%%%%%%%%%%1,344,000%%%%%%% 448,000%%%%%%%%%%%2,268,000%%%%%%% 756,000%%%%%%%%%%%378,000%%%%%%%%%%% 126,000%%%%%%%%%%%

5,320,000$%%%%% 1,904,000$%%%%%

Cost of Implementation � Case Study

�  23 harmonization teams with average of 9 members per team - meeting monthly year 1 and quarterly thereafter

�  Training an average of 20 people on an ongoing basis �  Quarterly surveys taking an average of 2 hours each

Team% FTE%% Yr%1 Yr%2%on RateTotal%Hrs

Yr%1 Yr%2Sponsor%&%Strategic%Partner

Harmonized+SOPs+ See+table 175+++++++++Alliance+Mgrs/Support 4 1 8160 8160 200+++++++++Development+of+PortalMetrics/Portal+maintenance 2 1 4080 4080 200+++++++++Consultants+to+support+implementationTraining 20 5% 1920 1920 175+++++++++Annual+Meeting 100 1% 1,200+++++ 1,200+++++ 175+++++++++Team+Surveys+ 100 0% 800

8,358,000+++++++ 2,089,500+++++++1,632,000+++++++ 1,632,000+++++++1,000,000+++++++ L++++++++++++++++++816,000+++++++++++ 816,000+++++++++++

1,300,000+++++++ L++++++++++++++++++336,000+++++++++++ 336,000+++++++++++460,000+++++++++++ 210,000+++++++++++

L++++++++++++++++++ L++++++++++++++++++13,902,000$%%% 5,083,500$%%%%%

Total Cost of Partnership � Case Study

SponsorTeam+ FTE+% Yr+1 Yr+2+on Rate Selection Yr+1 Yr+2

Selection)process 30 20% 12,240))) 4)))))))))) 200$))))))) 2,448,000$)))))

Cosulting)to)support)selection 1,100,000)))))))

Average)cost)of)reponse)and)two)selection)meetings)by)each)Provider 750,000)))))))))))

Exec)Gov)(Q) 10 3% 560 560 350))))))))) 196,000$)))))))) 196,000$))))))))

Operational)Gov)(M)first)yr)Q)therafter) 30 8% 5,040))))) 1,680))))) 225))))))))) 1,134,000))))))) 378,000)))))))))))

Program)Gov)(M)first)yr)Q)therafter) 40 8% 6720 2240 200))))))))) 1,344,000))))))) 448,000)))))))))))

Functional)Gov)(M)first)yr)Q)therafter) 60 8% 10,080))) 3,360))))) 225))))))))) 2,268,000))))))) 756,000)))))))))))

Joint)Quality)Council)(M)first)yr)Q)therafter) 10 8% 1680 560 225))))))))) 378,000))))))))))) 126,000)))))))))))

Harmonized)SOPs) See)table 175))))))))) 8,358,000))))))) 2,089,500)))))))

Alliance)Mgrs/Support 4 1 8160 8160 200))))))))) 1,632,000))))))) 1,632,000)))))))

Development)of)Portal 1,000,000))))))) 4))))))))))))))))))

Metrics/Portal)maintenance 2 1 4080 4080 200))))))))) 816,000))))))))))) 816,000)))))))))))

Consultants)to)support)implementation 1,300,000))))))) 4))))))))))))))))))

Training 20 5% 1920 1920 175))))))))) 336,000))))))))))) 336,000)))))))))))

Annual)Meeting 100 1% 1,200))))) 1,200))))) 175))))))))) 460,000))))))))))) 210,000)))))))))))

Team)Surveys) 100 0% 800 4)))))))))))))))))) 4))))))))))))))))))3,548,000$+++++ 19,222,000$+++ 6,987,500$+++++

Sponsor+&+Strategic+PartnerTotal+Hrs

Contact Information

Anthony Carita Email

Phone: 603-494-4490 Web: Synsource.us