Continuing Medical Education Questions: January 2014
Transcript of Continuing Medical Education Questions: January 2014
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© 2014 by the American College of Gastroenterology The American Journal of GASTROENTEROLOGY
nature publishing group CLINICAL AND SYSTEMATIC REVIEWS 35
RE
VIE
W
QUESTIONS:
1. Which one of the following statements refl ects the search
criteria for this systematic review and meta-analysis?
A. Only English-language articles were selected for
inclusion.
B. Abstracts were included in the search strategy.
C. Bibliographies of pertinent literature were manually
searched to fi nd other articles that may have been
missed.
D. PubMed and EMBASE were the primary search data-
bases.
2. Which one of the following statements is correct
regarding the studies that were selected for inclusion in
this systematic review and meta-analysis?
A. All included studies were randomized controlled trials.
B. All included studies were from either Europe or North
America.
C. All included studies surveyed a period between 2005
and 2013.
D. All included studies were primarily designed to assess
the impact of thiopurines on outcomes that included
surgery.
3. Which one of the following statements is correct
regarding the results of this systematic review and
meta-analysis?
A. Th e pooled hazard ratio for fi rst surgery among
thiopurine users was lower for population-based
studies than for hospital-based studies.
B. Th iopurine dose was found to predict a lower risk of
surgery.
C. Among patients exposed to thiopurines, there was a
41% risk reduction of fi rst intestinal surgery.
D. Th iopurine and methotrexate use were eff ectively
separated for meta-analysis purposes.
Continuing Medical Education Questions: January 2014
Kenneth R. DeVault, MD, FACG, Neel Choksi, MD and Shail Govani, MD
If you wish to receive credit for this activity, please refer to the Web site: http://acgjournalcme.gi.org/.
Article T itle: The Role of Thiopurines in Reducing the Need for Surgical Resection in Crohn’s Disease: A Systematic Review and Meta-Analysis
Am J Gastroenterol 2014; 109:35; doi:10.1038/ajg.2013.461
CME