Connective tissue and mesenchymal tissue...Connective tissue CT are divided into: 1. Connective...
Transcript of Connective tissue and mesenchymal tissue...Connective tissue CT are divided into: 1. Connective...
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Connective tissue &mesenchymal tissue
Prepared by: Ms. BR Tsauses
Anatomical Pathology 2A (ANP611S)
April 2020
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Learning objectives
• Understand connective and mesenchymal tissues in order to describe and apply appropriate staining techniques in Histology.
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Pre-learning Quiz
• Please take the pre-learning quiz before proceeding with the presentation.
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Introduction
• Connective tissue (CT) is of the four tissue types
• Derived fom latin word connectere meaning to bind.
• Is to connect together and provide support
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Introduction cont…
• During embryonic development: ectoderm + endoderm = mesoderm
• This germ layer is known as mesenchymal
• Mesos means middle
• Enchyma means infusion
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Connective tissue
CT are divided into:
1. Connective tissue proper (dense, areolar, regular,adipose regular and reticular
2. Cartilage (hyaline elastic, fibrocartilage)
3. Bone( spongy or cancellous and dense or cortical)
4. Blood
5. Blood-forming (hematopoietic)
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Connective tissue cell types
• Fibroblast
• Mast cells
• Histocytes
• Adipose cells
• Reticulor cells
• Osteoblast and osteocytes
• Chondroblast and chondrocytes
• Blood cells and blood forming cells
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Intercellular substance
• Intercellular substance (ICS) is composed of both amorphous(sulfated and non sulfated mucopolysaccharides) and formed elements (collagen, reticular fibers and elastic fibers)
• The nature of these substance varies according its function (hard or dense or soft.)
• Classified into: formed or fibrous type
: gel or amorphous type
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Formed or fibrous intercellular substances
Collagenenic fibers
• Most common ICS found in large quantities in most sites
• Appear as individual fibers as in loose areolar tissues e. g tendon
• Collagenic fibers do not branch
• Collagen types: Type (i) up to (vi)
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Reticular fibers
• Provide bulk of supporting network of more cellular organs e. g spleen, lymph nodes, liver.
• To support individual cell within the tissue.
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Elastic fibers
• Elastic fibers are associated with respiratory system, circulatory system and integumentary system
• Oxytalan fibers
• Elaunin fibers
• Lack structure or functional significance.
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Basement membrane
• Found throughout the body as resilient matrix separating connective tissue from epithelial
• Support epithelial cells
• Support epithelial cells lining blood vessels etc
• Divided into three zones or layers:
- lamina- rara (or lamina lucida)
- lamina densa (basal lamina)
- lamina reticularis
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Connective tissue
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Connective Tissue cont.
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Connective tissue cont (examples)…
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Connective tissue cont…
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Connective tissue…
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References
1. John D. Bancroft, Christopher Layton and S.Kim Suvarna, (2013),Bancroft’s Theory and Practice of Histological Techniques,7thEdition, Elsevier, China
2. J.A.Kiernan,(2015)Histological and Histochemical Methods, 5thEdition, Scion, UK