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COMPOSITION OF LIPIDS Lipoproteins Apolipoproteins Lipoproteins Apolipoproteins Cholesterol Protein Triglyceride Phospholipid

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Chylomicron Very Low Density Lipoprotein Low Density Lipoprotein Intermediate Density Lipoprotein High Density Lipoprotein Chylomicron Very Low Density Lipoprotein Low Density Lipoprotein Intermediate Density Lipoprotein High Density Lipoprotein

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CHOLESTEROL METABOLISM Exogenous Endogenous Reverse Cholesterol Transport LDL Uptake Exogenous Endogenous Reverse Cholesterol Transport LDL Uptake

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HMG CoA Reductase Inhibitors

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Fibric Acids TG synthesis lipoprotein synthesis excretion of lipoproteins from liver; primarily VLDL synthesis of cholesterol production of sterols HDL

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Bile Acid Binding Resins Nicotinic Acid Bind bile salts in gut Cholesterol eliminated in the feces Liver uses other sources of cholesterol (LDL) to make more bile

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Nicotinic Acid Inhibits liver secretion of VLDL Reduced serum LDL Inhibits removal of HDL Increases excretion of sterols in the feces

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Fibric Acids LDL VLDL TG Bile Acid Binding Resins HDL LDL VLDL TG HMG CoA Reductase Inhibitors Nicotinic Acid

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Dufaux, International Journal of Sports Medicine, 1982 TRIGLYCERIDES & TRAINING Increase Decrease No Change Numbers of Studies

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Dufaux, International Journal of Sports Medicine, 1982 CHOLESTEROL & TRAINING Increase Decrease No Change Numbers of Studies

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Dufaux, International Journal of Sports Medicine, 1982 LDL & TRAINING Increase Decrease No Change Numbers of Studies

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Dufaux, International Journal of Sports Medicine, 1982 HDL & TRAINING Increase Decrease or No Change Numbers of Studies

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Tolfrey K, et al Sports Medicine 29:99-112, 2000 Pediatric Triglyceride response to Exercise Increase Decrease No Change

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Increase Decrease No Change Numbers of Studies Pediatric Total Cholesterol response to Exercise Tolfrey K, et al Sports Medicine 29:99-112, 2000

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Increase Decrease No Change Numbers of Studies Pediatric LDL response to Exercise Tolfrey K, et al Sports Medicine 29:99-112, 2000

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Increase Decrease No Change Numbers of Studies Pediatric HDL response to Exercise Tolfrey K, et al Sports Medicine 29:99-112, 2000

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Hurley, B.F., MSSE 21:689-693, 1989. RESISTANCE TRAINING

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Hurley, B.F., MSSE 21:689-693, 1989.

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CHOLESTEROL & TRAINING Whaley et al, J Cardiopulm Rehab 12:42-50, 1992 Pre Post Total Cholesterol

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Lipid Research Clinics, JAMA 251:356-374, 1984. Reduction in Risk related to Reduction in Cholesterol

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Risk reduction associated with a 20.7 mg/dL reduction in Total Cholesterol Lipid Research Clinics, JAMA 251:356-374, 1984.

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Lehmann, R, et al. European J Clin Invest 31:37-44, 2001. HDL Subfractions and Physical Activity

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Lehmann, R, et al. European J Clin Invest 31:37-44, 2001. HDL Subfractions and Physical Activity

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Kraus, WE, et al. N Eng J Med 347:1483-1492, 2002 Exercise & Lipid Subfractions

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Kraus, WE, et al. N Eng J Med 347:1483-1492, 2002 Exercise & Lipid Subfractions

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Seip, RL. Et al. Arteriosclerosis and Thrombosis 13:1359-1367, 1993. HDL Subfractions and Physical Activity

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Seip, RL. Et al. Arteriosclerosis and Thrombosis 13:1359-1367, 1993. HDL Subfractions and Physical Activity

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Lp(a) and Physical Activity Seip, RL. Et al. Arteriosclerosis and Thrombosis 13:1359-1367, 1993.

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Lopez, A, et al Atherosclerosis 20:1-9, 1974. How does HDL change with exercise?

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Lopez, A, et al Atherosclerosis 20:1-9, 1974. How does HDL change with exercise?

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Grandjean, et al J Applied Physiology 89:472-480, 2000

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Hyper Normo Grandjean, et al J Applied Physiology 89:472-480, 2000

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CETP and Physical Activity Seip, RL. Et al. Arteriosclerosis and Thrombosis 13:1359-1367, 1993.