Complementary and Alternative Medicine Presentation by:

Terry Chhour

Leah Lopez

Polly Peru

Mark Reyes

Rachelle Sebastian

Learning Objectives:

● Provide current research

information on the potential

scientifically demonstrated

functions of turmeric concerning

its effectiveness on preventing

type 2 diabetes

● Traditional and modern uses

● Impeding its devastating

complications due to turmeric’s

ability to regulate insulin activity

and improve glucose control.

Turmeric

● Turmeric has been used as an

aromatic spice in Middle Eastern

and Southeast Asian cooking

● Medicinal instrument in

complementary health practices

for over 6,000 years.

● Complementary health

practitioners use turmeric in

the treatment of many chronic

illnesses such as diseases of

the eye, cancer, osteoarthritis,

ailments of the digestive

system, inflammation,

cardiovascular disease and

diabetes.

Description

● Turmeric is extracted from the rhizome (root) of the plant Curcuma

Longa.

➢ The rhizomes are boiled in water, drained, dried, and grounded into

turmeric powder

● Dried turmeric rhizomes yields 1.5-5% of essential oils, which are

responsible for its aromatic taste and smell

● The yellow color is derived from curcumin, which is the most active

component of the spice, and it makes up 2-5% of the spice.

Traditional and Modern Uses •Turmeric was regarded as the herb of the sun

and was viewed sacred.

A therapeutic agent in both the Indian and

Chinese systems of medicine

❖ Traditional Chinese Medicine (TCM):

liver problems, menstrual difficulties,

bloody urine, hemorrhage, toothache,

bruises and sores, chest pain and colic

❖ Ayurveda: acne, psoriasis, dermatitis,

rash, ulcers, and wounds

•Turmeric in Indian cuisine

• A beauty agent

• Turmeric is a major ingredient of curry

powder and is used in prepared mustard.

• It is also used extensively in many food

products, including baked goods, meat

and meat products, condiments and

relishes, fats and oils, egg products,

soups, and gravies.

• Turmeric (curcumin) is now marketed in

the form of capsules, tablets,

ointments, energy drinks, soaps, and

cosmetics.

• Several clinical reports states that

curcumin even at a high dose of 1000-

2000 mg/day does not produce any harmful

effect on human body (Choudhary et. al., 2013).

Turmeric in Capsules ● Meriva®, a lecithinized

formulation of curcumin was well tolerated, and preliminary findings suggest its usefulness in the management of diabetic microangiopathy

● Super Bio-Curcumin® which

absorbs up to seven times better than conventional curcumin represents the most cost-effective way to achieve greater peak blood levels

● Each 400 mg capsule of

Super Bio- Curcumin® is

equivalent to 2,772 mg of a typical 95% curcumin

Effectiveness and Efficacy • Improved beta-cell function • Prevented beta-cell degradation • Reduced inflammation by:

• Reducing C-reactive proteins

• Downregulation of inflammatory cytokines (tnf-a, leptin, and resistin)

• Prevented T2DM on prediabetics (Chuangsemarn et al., 2012)

• Significant decrease in fasting blood glucose levels and insulin resistance

• Decrease in serum total levels of: • FFAs • TAGs • Increase in lipoprotein

lipase activity (LPL)

(Na et al., 2013)

Nutrition Facts 100 g of turmeric contains : 390 kcal 10 g total fat 3 g saturated fat 0 mg cholesterol 0.2 g calcium 0.26 g phosphorous 10 mg sodium, 2500 mg potassium 47.5 mg iron 0.9 mg thiamin 0.19 mg riboflavin 4.8 mg niacin 50 mg ascorbic acid, 69.9 g total carbohydrates 21 g dietary fiber 3 g sugars 8 g protein Turmeric is also a good source of the ω-3 fatty acid and α-linolenic acid. Commercial

curcumin contains approximately 77% curcumin, 17% demethoxycurcumin, and 3% bisdemethoxycurcumin

Drug Interaction and Side Effects

● Diabetic Hypoglycemic

Drugs ● Anticoagulant Drugs ● Pregnant and Nursing

Women

Discussion and Conclusion ● Turmeric is a Middle Eastern, Southeast Asian

spice. ● Turmeric is biochemically, composed of Curcumin,

Demethoxycurcumin, and Bisdemethoxycurcumin; known as Curcuminoids

● Benefits:

- Help control blood glucose levels -Anti- inflammatory, Antioxidant, -Reduces free fatty acids in serum -No known adverse effects in high doses

● Limitations? - Not bioavailable - Supplement, rather than food additive - Most studies are on animals - Turmeric is not as prevalent in Western

countries - If it was, shown to be beneficial for

Pre-diabetic and diabetic populations

Questions?