Common Fetal Infections

8/11/2019 Common Fetal Infections

1/25

Cehhek Lbtfo DklbctdeksSmfkegfk Pmdyfafodkafh, Ejstbtrdcs & Aykfbceoeay


2/25

Eutodkb

6 Evbrvdbw el Lbtfo Dklbctdeks

:. PEZCM Dklbctdeks

F. Pexepofshf aek`dd

J. Prbpekbhf pfood uh

C. Zujboof

@. Cytehbafoevdrus

B. Muhfk Dhhuke`bstcdbkcy \drus

L. Mbrpbs Sdhpobx \drus


3/25

Evbrvdbw7 Cehhek ^ftmeabks Fllbctdka Lbtus

" Pexepofshf aek`dd (6/6>,>>> odvb jdrtms)

" Prbpekbhf pfood`uh (0/6>>> prbakfkt hetmbrs)

" Zujboof (3/ybfr)

" Cytehbafoevdrus (6/6>> jdrtms)

" Muhfk Dhhuke`bstcdbkcy \drus (?:>> jdrtms)

" Mbrpbs Sdhpobx \drus (4.,>>> odvb jdrtms)

"

Odstbrdf hekecyteabkbs

" Bscmbrdcmdf ceod

" Strbptececcus fafofctdfb

" Mbpftdtds

" ^frvevdrus J64

" Kbdssbrdf hbkdkadtd`ds

" Bktbrevdrusbs

" \frdcboof Westbr \drus

" Cexsfcidbvdrus

" ^frvevdrus

" Hfofrdf

" Areup J Strbptececcus

" ^fpdooehfvdrus

" Kbdssbrdf aekerrmebf

" Pujbrcuoesds

" Cmofhy`df trfcmehftds


4/25

Eutodkb

F. Pexepofshf aek`dd


5/25

Pexepofshf aek`dd

Prfkshdssdek7" Pe heh7 rfw hbft, ukpfstburdzb` aefts hdoi, cft lbcbs/urdkb" Pe jfjy7 trfkspofcbktfo

Arbftbst Prfkshdssdek Zdsi Pe Lbtus7" P3 (hest sbvbrb dl dklbctb` dk P6)

B!bct ek Lbtus" Cekabkdtfo Pexepofshesds

" Prdf`7 cmerderbtdkdtds, my`recbpmfoy, dktrfcrfkdfo cfocdstcftdek9 HZ, hdcrecbpmfoy" 12% el kbekftbs dkdtdfooy fsyhptehftdc ft jdrtm9 sbvbrdty `bpbk`s ek abstftdeks fab ft tdhb

el prdhfry dklbctdek

B!bct ek Hetmbr" hestoy sujcodkdcfo er u-odib syhptehs


6/25

Pexepofshf aek`dd

@dfakesds" Sbreoeay

" DaH (pbrsdsts ler ybfrs se cfkket cekstrh fcutb

dklbctdek)," DaA sbreoeay

" Fhkdetdc ^CZ

Hfkfabhbkt" Hftbrkfo

" dklbctdek ceklbrs dhhukdty9 prb-prbakfkcy

dklbctdek bodhdkftbs vbrtdcfo trfkshdssdek" Spdrfhycdk (`ebskt cress pofcbktf9 !lbtfo

herjd`dty jut ket rftb el trfkshdssdek)"

Lbtfo" pyrdhbtmfhdkb, suolf`dfzdkb, leodc fcd`" dl uktrbftb` !oeka tbrh sbqubofb

^rbvbktdek" ke vfccdkb" fved`7 cft odttbr jexbs, afr`bkdka wdtmeut aoevb/

hfsi `/t erafkdsh dk cft lbcbs


7/25

Eutodkb

J. Prbpekbhf pfood uh


8/25

Prbpekbhf pfood`uh

Prfkshdssdek" Pe heh7 sbxufo cektfct" Pe jfjy7 trfkspofcbktfo

Arbftbst Prfkshdssdek Zdsi Pe Lbtus" P6-P3

B!bct ek Lbtus" stdoojdrtm, my`reps lbtfods9 dl cmdo` survdvbs7 lfcdfo fjkerhfodtdbs (Mutcmdkseks tbbtm, sf``ob kesb,

smert hfxdoof), sfjbr smdks, CK = `bflkbss" bfroy (?: y/e) vs oftb (;: y/e) cekabkdtfo sypmdods


9/25

Prbpekbhf pfoodùh

@dfakesds" DaH fktdtrbpekbhfo fktdje`dbs (èkt cress pofcbktf)

" Scrbbkdka7" \@ZO/Z^Z ler foo prbakfkcdbs

" Cekstrhftdek7" LPF-FJS/HMF-P^"

@fri stbo` hdcrescepy dl prdhfry" R/S7 b`bhf, fscdtbs, my`reps, tmdcibkb` pofcbktf

Hfkfabhbkt" ^bkdcdoodk A :.0 hdoodek ukdts DH

" 6 èsb dl bfroy sypmdoods" 3 èsb dl oftb sypmdoods"

dl foobradc!

`bsbksdtdzftdek" Gfrdscm-Mbrxmbdhbr rbfctdek(utbrdkb cektrfctdeks fk` lbtfo mbfrt oftb `bcbo)

" dl pesdtdvb "\@ZO hektmoy

^rbvbktdek" dl uktrbftb` hetmbr!ftobfst ;1>% rdsi ler dklfkt dklbctdek (vs. 6-:% dl trbftb`)" cmbci tdtrb dk P6


10/25

Eutodkb

C. Zujboof


11/25

Zujboof

Prfkshdssdek7" Pe heh7 rbspdrftery `repobts (mdamoy cektfadeus)" Pe jfjy7 trfkspofcbktfo

Arbftbst Prfkshdssdek Zdsi Pe Lbtus7" mdambst dkP6

B!bct ek Lbtus" Cekabkdtfo Zujboof Syk`rehb

" Prdf`7 ^@F (er puohekfry frtbry mypepofsdf),

cftfrfcts fk` `bflkbss +/- joubjbrry hulstk rfsm" Etmbr7 hbktfo rbtfr`ftdek, dhpfcts erafks `urdka

erafkeabkbsds9 oftbkt eksbt7 tmyred`/ecuofr/arewtm

merhekb/`dfjbtdc dsbfsbs, MSH, tmrehjecytepbkdf,mypbrjdodrujdkbhdf

B!bct ek Hetmbr" rfsm (2>%), lbvbr, pestbrder furdcuofr er eccdpdtfo

oyhpmf`bkepftmy, frtmrfoadf


12/25

Zujboof

@dfakesds" sbreoeay7 foo prbakfkt wehbk scrbbkb`

(dhhukb dl tdtrb ;676


13/25

Eutodkb

@. Cytehbafoevdrus


14/25

Cytehbafoevdrus

Prfkshdssdek7" Pe heh7 joee` trfkslusdek, sfodvf, urdkb, erafk trfkspofkt, sbxufo cektfct

" 2>-=>% RS wehbk7 sbreoeadc bvd`bkcb" Pe jfjy7 trfkspofcbktfo, urdka `bodvbry, jrbfst hdoi

Arbftbst Prfkshdssdek Zdsi Pe Lbtus7"

P6-P3

B!bct ek Lbtus" mbfrdka oess, sbdzurbs, pbtbcmdfo rfsm, joubjbrry hulstk rfsm" 2-6>%7 CKS dkveovbhbkt

B!bct ek Hetmbr"

Fsyhptehftdc er hekekucobesds -odib syhptehs7" lbvbr, pmfrykadtds, oyhpmf`bkepftmy, peoyfrtmrdtds

" prdhfry dkl (herb sbvbrb) !oftbkt!rbfctdvftdek fk` smb``dka!sbcek`fry dkl (obss sbvbrb)


15/25

Cytehbafoevdrus

@dfakesds" sbreoeayscrbbk7 hftbrkfo DaH, DaA" VP-^CZ7 lbtfo joee`, fhkdetdc ud`" uotrfseuk`7 hdcrecbpmfoy, vbktrdcuoehbafoy, dktrfcrfkdfo cfocdstcftdek

" !sbksdtdvdty

Hfkfabhbkt" ke trbfthbkt" Afkcycoevdr (fkbc`etfo bvd`bkcb)

" ler syhptehftdc wdtm odlb/sdamt-tmrbftbkdka dookbss" FB7 tbstdcuofr ftrepmy, JH supprbssdek, btc

" ^rbvdeusoy dklbctb` dhhukesupprbssb` hetmbrs" hekdter DaA `/t rdsi ler cekabkdtfo CH\ rbtdkdtds

^rbvbktdek" hfdktfdk aee` myadbkb bspbcdfooy ft @fy Cfrb Cbktrbs" fved` mdam rdsi sdtuftdeks" prbvdeus CH\ dklbctdek `ebskt ceklbr dhhukdty (`dll strfdks)


16/25

Eutodkb

B. Muhfk Dhhuke`bstcdbkcy \drus


17/25

Muhfk Dhhuke`bstcdbkcy \drus

Prfkshdssdek7" Pe heh7 joee`, sbhbk, vfadkfo sbcrbtdeks" Pe jfjy7 dk utbre, `urdka `bodvbry, jrbfst hdoi, ZEH, dkvfsdvb precb`urbs

Arbftbst Prfkshdssdek Zdsi Pe Lbtus" 6/3 vdf utbre, 6/3 vdf `bodvbry, 6/3 vdf jrbfstlbb`dka

B!bct ek Lbtus" DRAZ, ^PO, ^ZEH

@dfakesds" scrbbk7 BODSF" cekstrh7 Qbstbrk joet, ^CZ


18/25

Muhfk Dhhuke`bstcdbkcy \drus

Hfkfabhbkt" Hftbrkfo

" trdpob fktdrbtrevdrfo tmbrfpy" Zfotbarfvdr, Oepdkfvdr, Wdèvu`dkb

" Wdèvu`dkb7 hekdter joee` ceukt/odvbr lukctdek" Kbekftb7 < wbbis el zdèvu`dkbsyrup"

bobctdvb C/S" blstcfcy7 !trfkshdssdek rftb jy


19/25

Eutodkb

L. Mbrpbs Sdhpobx \drus


20/25

Mbrpbs Sdhpobx \drus

Prfkshdssdek" Pe heh7 dktdhftb hucecutfkbeus cektfct" Pe jfjy7 trfkspofcbktfo (2%), `urdka `bodvbry (=2%), pestkftfo

(6>%)

Arbftbst Prfkshdssdek Zdsi Pe Lbtus"

`bodvbry (dl abkdtfo obsdeks prbsbkt)9 obss cehhek dk-utbre" prdhfry dklbctdek (2>%) vs. sbcek`fry dklbctdek (?6-2%)

B!bct ek Lbtus (3 lerhs)" 6) sidk(sehbtdhbs), byb, heutmwdtm oecfodzb` dkveovbhbkt" :) CKS`dsbfsb wdtm bkcbpmfodtds" 3) `dssbhdkftb``dsbfsb wdtm huotdpob erafk dkveovbhbkt

B!bct ek Hetmbr" kuhjkbss, tdkaodka, pfdk (pre`rehfo syhptehs), pfdkluo

vbsdcuofr obsdeks w/ brytmbhfteus jfsb tmft mbfo w/e scfrrdka


21/25

Mbrpbs Sdhpobx \drus

@dfakesds7" Codkdcfo" Lbtfo vdrfo cuoturbel mbrpbtdc obsdeks, erepmfrykx, byb" Hftbrkfo sbreoeay

" prdhfry dklbctdek (sbvbrb)7 DaH" sbcek`fry dklbctdek (obss sbvbrb)7 DaA

Hfkfabhbkt" wmbk pt prbsbkts dk ofjer

" fsi fjeut pre`rehfo syhptehs" bxfhdkb pbrdkbuh, vfadkf, cbrvdx ler obsdek

" D\ fcycoevdr7 !syhpteh obkatm, fheukt vdrfo smb``dka9

prepmyofxds dl mx el dklbctdek" C/S dl pre`rehfo er fctdvb abkdtfo obsdeks" dl prdhfry hftbrkfo dklbctdek coesbr te `bodvbry #lftfo

" obss tdhb ler hftbrkfo Fj te pfss te lbtus

^rbvbktdek7" scrbbk7 hftbrkfo pbrdkbfo bxfh" dl abkdtfo obsdeks tmbk `e C/S" dl mx el mbrpbs jut ke currbkt eutjrbfi dk prbakfkcy tmbk sehb

`ecters advb fcycoevdr


22/25

Mdam Tdbo` Suhhfry

Seurcb7 Jfxtbr, S. (:>6:). Dklbctdeks @urdka rbakfkcy. Dk Pmb Perekte ketbs :>6:7 F cehprbmbksdvb hb`dcfo rblbrbkcb fk` rbvdbw ler tmb Hb`dcfo Ceukcdo el Cfkf`f Vufodlydka Bxfh - ^frt 6 fk` tmb Rkdtb` Stftbs Hb`dcfo OdcbksdkaBxfh - Stbp : (:=tm b`., p. EJ::). Perekte7 Perekte Ketbs ler Hb`dcfo Stu`bkts.


23/25

Mdam Tdbo` Suhhfry

Seurcb7 Jfxtbr, S. (:>6:). Dklbctdeks @urdka rbakfkcy. Dk Pmb Perekte ketbs :>6:7 F cehprbmbksdvb hb`dcfo rblbrbkcb fk` rbvdbw ler tmb Hb`dcfo Ceukcdo el Cfkf`f Vufodlydka Bxfh - ^frt 6 fk` tmb Rkdtb` Stftbs Hb`dcfo OdcbksdkaBxfh - Stbp : (:=tm b`., p. EJ::). Perekte7 Perekte Ketbs ler Hb`dcfo Stu`bkts.


24/25

Zblbrbkcbs

" Jfxtbr, S. (:>6:). Dklbctdeks @urdka ^rbakfkcy. Dk Pmb Perekte ketbs :>6:7 F cehprbmbksdvb

hb`dcfo rblbrbkcb fk` rbvdbw ler tmb Hb`dcfo Ceukcdo el Cfkf`f Vufodlydka Bxfh - ^frt 6 fk` tmb

Rkdtb` Stftbs Hb`dcfo Odcbksdka Bxfh - Stbp : (:=tm b`., p. EJ::). Perekte7 Perekte Ketbs ler

Hb`dcfo Stu`bkts.

" Adojbrt, Z., & btbrsbk, B. (:>63, Kevbhjbr 63). Pexepofshesds fk` prbakfkcy. Zbtrdbvb`

Sbptbhjbr :4, :>60, lreh mttp7//www.upte`ftb.ceh/cektbkts/texepofshesds-fk`-prbakfkcy5seurcb8prbvdbw&sbfrcm8texepofshf aek`dd prbakfkcy&sbobctb`Pdtob86~62>&ofkaufab8bk-

RS&fkcmer8M2#M2

" Gemksek, I. (:>60, Gfkufry 62). Evbrvdbw el PEZCM dklbctdeks. Zbtrdbvb` Sbptbhjbr :4, :>60,

lreh mttp7//www.upte`ftb.ceh/cektbkts/evbrvdbw-el-tercm-dklbctdeks5

seurcb8sbfrcmUrbsuot&sbfrcm8tercmbs dklbctdeks&sbobctb`Pdtob86~62>#M6

" Ifulhfk, H., Meohbs, G., Scmfcmbo, ^., & Stbf`, O. (:>66). Dklbctdeks Dk ^rbakfkcy. Dk Ldrst fd` ler

tmb ejstbtrdcs & aykfbceoeay cobrismdp(3r` b`., pp. 62


25/25

Bk` el ^rbsbktftdek

Common Fetal Infections

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