Comment on “Chromosomal Instability and Tumors Promoted by DNA Hypomethylation” and “Induction of

Tumors in Mice by Genomic Hypomethylation”

by Allen S. Yang, Marcos R.H. Estecio, Guillermo Garcia-Manero, Hagop M. Kantarjian, and Jean-Pierre J. Issa

ScienceVolume 302(5648):1153b-1153b

November 14, 2003

Published by AAAS

Fig. 1. Alu and LINE-1 methylation in primary colon tumors and cancer cell lines.

Allen S. Yang et al. Science 2003;302:1153b

Published by AAAS

Fig. 2. Demethylation of Alu elements by 5-aza-dC in patients with leukemia.

Allen S. Yang et al. Science 2003;302:1153b

Published by AAAS