CME 2014 presentation
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Transcript of CME 2014 presentation
Future of the Medicine Cellular Medicine
Dr. Pradeep MahajanStem Cells Transplant Expert | Founder @ StemRx Bioscience Solutions Pvt, ltd. India
Life Expectancy. Future of Medicine – Next 100 years. Cellular Medicine – What’s so new? Drug Discovery in a dish. Organ Shop- fiction or reality?. A paradigm shift from traditional medicine to
cellular medicine – New dimensions . Cellular medicine and Therapeutic
Applications.
Talk Outline
Limitations of proven therapies No longer medical science has remained the
domain of only physicians, clinicians . Researchers in Regenerative Medicine
developing new protocols.
Gradual increase in Life expectancy
Introduction
Antibiotics, vaccines
SanitizationSuperstitious
Visualize the future of medicine in next 100 years
Future of medicine – next 100 years
Tele-medicine-• Internets Skype• Virtual consultations• Satellite – Robotic/ diagnostics•Google Mirror –Using Sensor technology with hardware & Software with internet•Holographic consultations with doctors
Digital Medicine-• I phones• Digitalization of histopathology• Brain computed chips• Artificial augmented limbs
Robotic Medicine-• Robotic Minimal invasive surgeries• Robotic tele assisted surgeries• Intelligent autonomous robotic surgeries with high speed & resolution MRI• I-knives with cancer therapies
Cancer- No more Mystery- Cancer gene Chemotherapy, Radiotherapy- Non specific
Patient specific , organ specific & disease specific personalized therapy• DNA chips• Nanoparticles – Magnetic/ Antibody
Cell Based Therapies• DC cells• T cells• NK cells
Genomic & Molecular Medicine-Gene is software Protein is hardware• Genetic engineering• Proteomics
• Nanotechnology- applications in•Cancer •Metabolic and •Genetic diseases
DNA / Gene is software protein is hardware
Man made Macro Machines
Nature made Nano Machines
Electric Fence Membrane
Transporters Hb
Digital database Nucleus
Bulldozers Proteosomes
Control centers Centrosomes
Chain couplers Ligase
Internet Nodes Neural System
“ About 1000 years ago, humans domesticated plants and animals….now its time to domesticate molecules”
Cellular Medicine coupled with digital medicine, telemedicine , nanomedicine can create wonders………
-Use of miraculous stem cells
-Advanced applications of stem cells
-Curative medicine
The first major revolution……..Its not the science fiction – It’s the stem cells research……
“ Hope and dreams for stem cells – we live in a time where the word impossible and unsolvable are no longer part scientific communities vocabulary. Each day we move closer to trials that will not just minimize the symptoms of diseases and injuries but eliminate them”
- Christopher Reeve
( Superman )
In fact he introduced stem cells research legacy to the world
Imagine……….
Research
Dolly the Sheep
Ethical & Social Issues
ESC- Embryonic Stem Cells
Invention of IPSC’s – Reprogramming of somatic skin cells,
Embryonic Transcription factors : Oct4, Sox2, KLF4, Cmyc
Developing all 220 types of cells.
“ Its not a science fiction . Its stem cells research led to never before in the history of medical science. Such a gift received to humans – Stem Cells- which can regenerate the cells to tissue to the organs”
Science of personalized organ specific medicine
Somatic cells/ Stem Cells
Transplanted back
iPSC/ Stem Cells
Culture
Differentiation
Drug Discovery in a dish
Dustan & Haffman ( 1960 )
Biodegradable scaffolds (2012)
Body Organ Shop
Future is organ development in a dish!!!!
Breakthrough achievement in organ transplant……
The technologies for organ development 1. 3D printing technology2. Scanner technology3.Cadaver organs like liver, kidney by
washing out cellular material
Cellular Medicine – What’s so new
Cells Scaffolds
Regenerative Medicine
Grafts
Bioengineering and repair of the damaged tissue with the help of cells in scaffolds
Organ Shop
Stem cells and biological products as drugs
- PRP kits- Specialized cells developed in Petri dishes- Different cell lines like cardio-myocytes, osteocytes, chondrocytes etc…
Bone Marrow Aspiration
Adipose Tissue Aspiration
Harvesting of stem cells
Injecting Cells inside the body
Stem Cells to differentiate and form different tissues and organs
How does it work ?
Cellular Medicine & Robotics
Cellular Medicine & Genomics
Cellular Medicine & Proteomics
Healing Force Of The Future
VSEL’s T – Regulatory cells EPC NK,T, DC T-Regulatory Cytokines- Micro-medicineAnd many more…………
Advances in the new cell lines….
Therapeutic Applications of Cellular Medicine………
Applications of Stem Cells….
More than 4000 patients treated One of the leader in therapeutic
applications of stem cells Full equipped facility for sample
processing, research and quality control Trained laboratory and clinical personnel Conducting PhD/ M.Sc courses in Stem
cells in collaboration with ITM Currently working on several research
projects covering most of the clinical disorder in human being
StemRx in cellular medicine
T-regulatory cell Therapy for immune modulation .
Applications of Vsel cell. Cytokines and growth hormones for
oral and injectable therapies. DC T-cell and NK Cell therapies .
StemRx in Future
“ So many of our dreams at first looked impossible …then improvable …but when we summon the will , they soon become inevitable..”
Thank You…….