Cm chapter 101. The functions of the CSF include all of the following

except:

A. Removal of metabolic wastes

B. Producing an ultrafiltrate of plasma

C. Supplying nutrients to the CNS

D. Protection of the brain and spinal cord2. The CSF flows through the:A. Choroid plexusB. Pia mater

C. Arachnoid spaceD. Dura mater

3. Substances present in the CSF are contolled by the:

A. Arachnoid granulations B. Blood-brain barrier

C. Presence of one-way valves D. Blood-CSF barrier

4. The CSF tube labeled 3 is sent to:

A. The hematology department B. The chemistry dptC. The microbiology department D. The serology dpt5. The CSF tube that should be refrigerated is:

A. Tube 1

B. Tube 2

C. Tube 3

D. Tube 4

6. Place the appropriate letter in front of the statement

that best describes CSF specimens in these two conditions:

A. Traumatic tap

B. Intracranial hemorrhage_____Even distribution of blood in all tubes

_____Xanthochromic supernatant

_____Concentration of blood in tube 1 is greater

than in tube 3

_____Specimen contains clots7. The presence of xanthochromia can be caused by all

of the following except:A. Immature liver function B. RBC degradation

C. A recent hemorrhage D. Elevated CSF protein8. A web-like pellicle in a refrigerated CSF specimen is

indicative of:A. Tubercular meningitis B. Multiple sclerosis

C. Primary CNS malignancy D. Viral meningitis9. Given the following information, calculate the CSF

WBC count: cells counted, 80; dilution, 1:10; large

Neubauer squares counted, 10.A. 8

B. 80

C. 800

D. 800010. A CSF WBC count is diluted with:A. Distilled waterB. Normal saline

C. Acetic acidD. Methylene blue11. A total CSF cell count on a clear fluid should be:A. Reported as normal B. Not reported

C. Diluted with normal saline D. Counted undiluted

12. The purpose of adding albumin to CSF before

cytocentrifugation is to:A. Increase the cell yield

B. Decrease the cellular distortion

C. Improve the cellular staining

D. Both A and B13. The primary concern when pleocytosis of neutrophils

and lymphocytes is found in the CSF is:A. Meningitis

B. CNS malignancy

C. Multiple sclerosisD. Hemorrhage14. Neutrophils with pyknotic nuclei may be mistaken for:A. LymphocytesB. Nucleated RBCs

C. Malignant cellsD. Spindle-shaped cells15. The presence of which of the following cells is

increased when a CNS shunt malfunctions?A. NeutrophilsB. Macrophages

C. Eosinophils

D. Lymphocytes16. Macrophages appear in the CSF following:A. HemorrhageB. Repeated spinal taps

C. Diagnostic proceduresD. All of the above17. Nucleated RBCs are seen in the CSF as a result of:A. Elevated blood RBCs B. Treatment of anemia

C. Severe hemorrhage D. Bone marrow contamination18. Following a CNS diagnostic procedure, which of the

following might be seen in the CSF?A. Choroidal cellsB. Ependymal cells

C. Spindle-shaped cellsD. All of the above19. Hemosiderin granules and hematoidin crystals are

seen in:

A. LymphocytesB. Macrophages

C. Ependymal cellsD. Neutrophils20. Myeloblasts are seen in the CSF:A. In bacterial infections

B. In conjunction with CNS malignancy

C. Following cerebral hemorrhage

D. As a complication of acute leukemia21. Cells resembling large and small lymphocytes with

cleaved nuclei represent:A. Lymphoma cellsB. Choroid cells

C. Melanoma cellsD. Medulloblastoma cells22. The normal value of CSF protein is:

A. 68 g/dL

B. 1545 g/dL

C. 68 mg/dLD. 1545 mg/dL23. CSF can be differentiated from plasma by the presence of:A. Albumin

B. Globulin

C. Prealbumin

D. Tau transferring24. In plasma, the second most prevalent protein is IgG;

in CSF, the second most prevalent protein is:A. Transferrin

B. Prealbumin

C. IgA

D. Ceruloplasmin25. Elevated CSF protein values can be caused by all of

the following except:A. Meningitis

B. Multiple sclerosis

C. Fluid leakageD. CNS malignancy26. The integrity of the blood-brain barrier is measured

using the:A. CSF/serum albumin index B. CSF/serum globulin ratio

C. CSF albumin index D. CSF IgG index27. Given the following results, calculate the IgG index:

CSF IgG, 50 mg/dL; serum IgG, 2 gm/dL; CSF albumin,

70 mg/dL; serum albumin, 5 gm/dL.A. 0.6

B. 6.0

C. 1.8

D. 2.828. The CSF IgG index calculated in Study Question 27

is indicative of:A. Synthesis of IgG in the CNS

B. Damage to the blood-brain barrier

C. Cerebral hemorrhage

D. Lymphoma infiltration29. The finding of oligoclonal bands in the CSF and not

in the serum is seen with:A. Multiple myelomaB. CNS malignancy

C. Multiple sclerosisD. Viral infections30. A CSF glucose of 15 mg/dL, WBC count of 5000, 90%

neutrophils, and protein of 80 mg/dL is suggestive of:A. Fungal meningitisB. Viral meningitis

C. Tubercular meningitisD. Bacterial meningitis31. A patient with a blood glucose of 120 mg/dL would

have a normal CSF glucose of:A. 20 mg/dL

B. 60 mg/dL

C. 80 mg/dL

D. 120 mg/dL32. CSF lactate will be more consistantly decreased in:A. Bacterial meningitisB. Viral meningitis

C. Fungal meningitisD. Tubercular meningitis33. Measurement of which of the following can be

replaced by CSF glutamine analysis in children with

Reye syndrome?A. Ammonia

B. Lactate

C. Glucose

D. _-ketoglutarate34. Prior to performing a Gram stain on CSF, the specimen

must be:

A. Filtered

B. Warmed to 37_C

C. CentrifugedD. Mixed35. All of the following statements are true about cryptoccocal meningitis except:A. An India Ink preparation is positive

B. A starburst pattern is seen on Gram stain

C. The WBC count is over 2000

D. A confirmatory immunology test is available36. The test of choice to detect neurosyphilis is the:

A. RPR

B. VDRL

C. FTA

D. FTA-ABS