Cloning & Gene Therapy Notes

• Warm up: You have 12 min to complete Woolly Mammoth Cloning.

• HW check from yesterday.

Genetic Screening• Test DNA to detect genetic diseases

– determines risk of havingor passing on a geneticdisorder

– can detect genesrelated to an increasedrisk of cancer

– can detect some genesknown to cause geneticdisorders

DMD N

Gene Therapy

• Is the replacement of faulty genes• Gene therapy replaces defective or missing

genes, or adds new genes, to treat a disease.

Gene Therapy

• Has many technical difficulties– Inserting gene into correct cell– Determining effect on other genes

• Only way to cure genetic disease is to change the affected DNA

Cloning• A clone is a genetically identical copy of a gene or of an

organism.

Cloning

• Cloning occurs in nature.

– bacteria (binary fission)– some simple animals (budding, regeneration)– Identical twins

Cloning• Mammals can be cloned through a process called

nuclear transfer.– nucleus is removed from an egg cell– nucleus of a cell from the animal to be cloned is

implanted in the egg

Benefits of Cloning

• Human organ transplants• Save endangered species

Concerns of Cloning

• Low success rate• Clones less healthy than original• Ethical controversy

Jurassic park