C lin ic a l C lin ic a l Tr ia ls :Tr ia ls :A c u t e A c u t e K id n e y K id n e y D is e a s eD is e a s e

B y: M attea L oganB y: M attea L ogan

H a v e y o u e v e r H a v e y o u e v e r d r e a m t o f t h e d a y , d r e a m t o f t h e d a y , w h e n a ll i l ln e s s e s w h e n a ll i l ln e s s e s w o u ld b e c u r e d ?w o u ld b e c u r e d ?

HIV/AIDSHIV/AIDSChicken poxChicken pox AsthmaAsthma

Cervical cancer

Breast cancer

Cerebral Palsy

Acute Kidney Failure

R h e uma to id Arth ritis

Sinus infections

Sexual Transmitted diseases

Solution Solution Clinical Clinical TrialsTrials

Clinical Trials?

Clinical trials are comparison tests of a medication or other medical

treatment on people. They are conducted to collect accurate data

on new drugs, devices, or procedures while assuring the

safety of the participants.

For ExampleFor Example

Glaucoma and Marijuana:Glaucoma and Marijuana:

Many researchers are Many researchers are performing clinical trials performing clinical trials to prove that marijuana to prove that marijuana (or its components), (or its components), taken orally or by taken orally or by inhalation, can lower inhalation, can lower intraocular pressure.intraocular pressure.

With-Out Clinical TrialsWith-Out Clinical Trials If there were no clinical If there were no clinical

trials many doctors would trials many doctors would be performing trial and be performing trial and error procedures on real error procedures on real patients. Medicine and patients. Medicine and medical technology medical technology would advance slowly, if would advance slowly, if at all. In a sense, most at all. In a sense, most modern medical modern medical advances can be credited advances can be credited to that small army of to that small army of heroic volunteers who heroic volunteers who have participated in have participated in clinical trials!clinical trials!

THEBenefits

&

Risks

Benefits

Play an active role in their own health care.

Gain access to new research treatments before they are widely available.

Obtain expert medical care at leading health care facilities during the trial.

Help others by contributing to medical research.

One more…! A paid experiment.

Most clinical trials are time consuming and require the participant to be dedicated. The study will generally reimburse the participant for their time and expenses.

RisksThe experimental

treatment may not be effective for the participant. There may even be unpleasant side effects.

The protocol may require more of their time and attention.

Acute Kidney Failure

Acute Kidney FailureAcute Kidney FailureAcute kidney FailureAcute kidney Failure isis

the sudden loss of your the sudden loss of your kidneys' ability to perform kidneys' ability to perform their main function — their main function — eliminate excess fluid as eliminate excess fluid as well as waste material from well as waste material from your blood. When your your blood. When your kidneys lose their filtering kidneys lose their filtering ability, dangerous levels of ability, dangerous levels of fluid, and waste accumulate fluid, and waste accumulate in your body.in your body.

As a result, doctors perform As a result, doctors perform dialysisdialysis, to help remove , to help remove toxins and excess fluids toxins and excess fluids from your body while your from your body while your kidneys heal. kidneys heal. DialysisDialysis, , which is a mechanical which is a mechanical way of filtering waste way of filtering waste from your blood, is an from your blood, is an imperfect but lifesaving imperfect but lifesaving substitute for kidney substitute for kidney function.function.

Where do Clinical Trials fit in?Where do Clinical Trials fit in?

A group of researchers A group of researchers at UCSD Medical at UCSD Medical Center are currently Center are currently researching an researching an easier and less time easier and less time consuming way to consuming way to perform dialysis.perform dialysis.

Instead of the Instead of the traditional trip to the traditional trip to the hospital 3 times a hospital 3 times a week, staying at a week, staying at a minimum of 4 hours minimum of 4 hours each visit, a patient each visit, a patient can come for can come for dialysis, for only an dialysis, for only an hour everyday.hour everyday.

In SummationIn SummationClinical Trials are:Clinical Trials are: Beneficial- towards Beneficial- towards

peoples health, and helps peoples health, and helps improve technology. improve technology.

Efficient-Trials are run by Efficient-Trials are run by proficient doctors and proficient doctors and researchers who are researchers who are knowledgeable and well knowledgeable and well trained in their field. trained in their field.

Consistent- a consistent Consistent- a consistent trial will get straight to the trial will get straight to the point. point.

Your time and Your time and consideration is all consideration is all that is needed.that is needed.

Got Clinical Trials?Got Clinical Trials?

CreditsCredits

Produced by students from Helix Charter Produced by students from Helix Charter High School La Mesa, CA. In partnership High School La Mesa, CA. In partnership

with the University of California at San with the University of California at San Diego, School of Medicine under a Diego, School of Medicine under a

Science Education Partnership Award. Science Education Partnership Award. (SEPA grant number R25RR022714) (SEPA grant number R25RR022714) from the National Institutes of Health.from the National Institutes of Health.