CKD Module 1
Transcript of CKD Module 1
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Achieve your goals.
Make a difference.Join a community of caring.
DiscoverNephrology Nursing
American Nephrology Nurses Association
www.annanurse.org
This presentation is supported by an unrestricted educational grantprovided by the Nurse Competence in Aging Initiative.
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Stage 1 - Kidney Damage (Normal or GFR >90)
Action taken by Medical Personnel:
Diagnosis and Treatment
Treat comorbid diseases Slow progression of disease through diet and medication
Stage 2 - Mild Kidney Damage (GFR
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Stage 3 - Moderate Kidney Damage (GFR
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Stage 5 - Kidney Failure (GFR
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Chronic Kidney Disease (CKD)
Chronic Kidney Disease (CKD) is a progressive loss of renal function.The etiology of CKD can be from a variety of diseases including butnot limited to:
Diabetes Mellitus Glomerularnephritis
Interstitial nephritis Vasculitis
Chronic pyelonephritis Obstructive disorders
Hypertension
Hereditary disease
Congenital disorders Cystic disease
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The Kidney
The kidneys weigh about 1/2 pound each.
They are located in the retroperitonealspace.
They are about the size of an adult fist
They are shaped like a kidney bean.
They are attached to the blood stream
through the renal arteries.
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Nephrons
Nephrons are themicroscopic functionalunit of the kidney.
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Functions of the Kidneys
Remove wastes
Remove excess fluid
Secrete erythropoietin
Regulate bone metabolism
Regulate blood pressure
Regulate acid-base balance
Regulate electrolyte balance
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What is Renal Failure?
Acute Renal Failure
Chronic Renal Failure
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Symptoms of Chronic Renal Failure (Uremia)
Loss of appetite
Nausea/vomiting
Headache
Shortness of breath
Itching
Bone disease
Anemia
Proteinuria
Weakness, insomnia
Hypertension
Edema
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Symptoms of Chronic Renal Failure (Uremia)
Loss of appetite
Nausea/vomiting
Headache
Shortness of breath
Itching
Bone disease
Anemia
Proteinuria
Weakness, insomnia
Hypertension
Edema
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Renal Replacement Therapy (RRT)(Used for Patients at Stage 5)
HemodialysisPeritoneal Dialysis
Transplantation
No therapy
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History of Dialysis
1913 Artificial kidney used in animals.
1935 Heparin purified.
1942 First patient treated with dialysis machine. 1950s Hemodialysis used to treat acute renal failure.
1960 External arteriovenous shunt developed by Drs. Scribner andQuinton.
1965 Internal arteriovenous fistula developed by Drs. Brescia and Cimino.
1972 Medicare ESRD Program established.
1989 - Recombinant human erythropoietin (Epogen) approved by the FDA.
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History of Dialysis
1913 Artificial kidney used in animals.
1935 Heparin purified.
1942 First patient treated with dialysis machine. 1950s Hemodialysis used to treat acute renal failure.
1960 External arteriovenous shunt developed by Drs. Scribner and Quinton.
1965 Internal arteriovenous fistula developed by Drs. Brescia andCimino.
1972 Medicare ESRD Program established.
1989 Recombinant human erythropoietin (Epogen) approved by theFDA.
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Types of Hemodialysis Treatments In Hospital Some communities have dialysis center
located in the hospital.
In-center Most people on dialysis dialyze in a dialysis clinic.
Self-care There are some facilities where patients withoutpartners can do their own care in a clinic setting.
Home Patients are trained along with a partner todialyze at home.
Nocturnal Nocturnal dialysis involves dialyzing 5 to 7nights a week for 8 to 10 hours.
May or maynot have partners
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Basic Treatment
Hemodialysis removes
solutes (waste particles)and fluid from the bloodacross a semipermeablemembrane in a filter(dialyzer).
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Components for Hemodialysis Access to circulation: need to
pull blood from, and returnblood to the body, at a speed
of 200-500 mL/ min
Dialyzer (artificial kidney)
Dialysate (Bath)
Dialysis machine
Water treatment
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Components for Hemodialysis Access to circulation: need to
pull blood from, and returnblood to the body, at a speed
of 200-500 mL/ min
Dialyzer (artificial kidney)
Dialysate (Bath)
Dialysis machine
Water treatment
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Components for Hemodialysis Access to circulation: need to
pull blood from, and returnblood to the body, at a speed
of 200-500 mL/ min
Dialyzer (artificial kidney)
Dialysate (Bath)
Dialysis machine
Water treatment
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Components for Hemodialysis Access to circulation: need to
pull blood from, and returnblood to the body, at a speed
of 200-500 mL/ min
Dialyzer (artificial kidney)
Dialysate (Bath)
Dialysis machine
Water treatment
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Components for Hemodialysis Access to circulation: need to
pull blood from, and returnblood to the body, at a speed
of 200-500 mL/min
Dialyzer (artificial kidney)
Dialysate (Bath)
Dialysis machine
Water treatment
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Caring for the Dialysis Patient includes:
RRT (Renal Replacement Therapy).
Diet and fluid management. Medication regimens.
Rehabilitation services.
Community services.
Social support.
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Assessment of the CKD Patient
Assess fluid status
Restrict fluid intake
Control dietary intake
Properly administer medications
Evaluate blood pressure
Check access daily
Watch for side effects
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Assessment of the CKD Patient
Assess fluid status
Restrict fluid intake
Control dietary intake
Properly administer medications
Evaluate blood pressure
Check access daily
Watch for side effects
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Assessment of the CKD Patient
Assess fluid status
Restrict fluid intake
Control dietary intake
Properly administer medications
Evaluate blood pressure
Check access daily
Watch for side effects
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Assessment of the CKD Patient
Assess fluid status
Restrict fluid intake
Control dietary intake
Properly administer medications
Evaluate blood pressure
Check access daily
Watch for side effects
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Assessment of the CKD Patient
Assess fluid status
Restrict fluid intake
Control dietary intake
Properly administer medications
Evaluate blood pressure
Check access daily
Watch for side effects
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Assessment of the CKD Patient
Assess fluid status
Restrict fluid intake
Control dietary intake
Properly administer medications
Evaluate blood pressure
Check access daily
Watch for side effects
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Assessment of the CKD Patient
Assess fluid status
Restrict fluid intake
Control dietary intake
Properly administer medications
Evaluate blood pressure
Check access daily
Watch for side effects
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Potential Problems During Dialysis
Hypotension
Nausea
Cramping
Headache
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Potential Problems Between Treatments Hypotension
Symptoms: Dizziness, sweaty/clammy, nausea, cramping.
Causes: Removing too much fluid during dialysis.Co-morbid conditions.Patient may be taking B/P medications prior to dialysis.
Prevention: Take B/P medications after dialysis instead ofprior to dialysis.
If the patient experiences nausea and vomiting, report this to thedialysis staff prior to dialysis treatment.
Communicate with the dialysis staff if the patient goes to dialysiswearing a nitroglycerin patch.
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Potential Problems Between Treatments Hypotension
Symptoms: Dizziness, sweaty/clammy, nausea, cramping.
Causes: Removing too much fluid during dialysis.Co-morbid conditions.Patient may be taking B/P medications prior to dialysis.
Prevention: Take B/P medications after dialysis instead ofprior to dialysis.
If the patient experiences nausea and vomiting, report this to thedialysis staff prior to dialysis treatment.
Communicate with the dialysis staff if the patient goes to dialysiswearing a nitroglycerin patch.
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Potential Problems Between Treatments Hypotension
Symptoms: Dizziness, sweaty/clammy, nausea, cramping.
Causes: Removing too much fluid during dialysis.Co-morbid conditions.Patient may be taking B/P medications prior to dialysis.
Prevention: Take B/P medications after dialysis instead ofprior to dialysis.
If the patient experiences nausea and vomiting, report this to thedialysis staff prior to dialysis treatment.
Communicate with the dialysis staff if the patient goes to dialysiswearing a nitroglycerin patch.
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Problems Between Treatments
Nausea
Causes: Can be due to B/P, medications,uremia, and electrolyte imbalance.Evaluate the B/P to determine if nauseais related to cardiovascular instability.
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Potential Problems Between Treatments
Headaches
Leg cramps
Skin integrity
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Potential Problems Between Treatments Hypoglycemia
Symptoms: Shaking, fast heart beat, weakness.
Causes: Too little food or too much insulin.
Treatment: Test blood sugar.
Hyperglycemia
Symptoms: Extreme thirst, nausea, blurred vision.
Causes: Too much concentrated sweets not enough insulin. Treatment: Insulin as ordered by MD.
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Potential Problems Between Treatments Hypoglycemia
Symptoms: Shaking, fast heart beat, weakness.
Causes: Too little food or too much insulin.
Treatment: Test blood sugar.
Hyperglycemia
Symptoms: Extreme thirst, nausea, blurred vision.
Causes: Too much concentrated sweets not enough insulin. Treatment: Insulin as ordered by MD.
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Potential Problems Between Treatments
Access Site Bleeding
Symptoms: Excessive or prolonged bleeding at dialysis access site.
Causes: Not rotating needle sites, too much heparin.
Treatment: Manual pressure for 10 to 20 minutes; hemostaticagents may be used; in extreme cases, send the patient tothe emergency room.
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Vascular Access Types
Internal
Fistula
Graft
PTFE
Bovine
Vectra
External
Catheter
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Vascular Access
Fistula
Check for bruit and thrill daily.
May remove band-aids next morning.
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Vascular Access
Graft
PTFE
Bovine
Vectra
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Vascular Access
EXTERNAL
Catheter
Keep dressing dry.
Call dialysis unit if end caps come off.
Notify unit if dressing has drainage.
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Daily Checks of Vascular Access Inspection of Access Condition of skin over access
Redness
Auscultation of Access
Bruit +/-
Quality/character
Palpation of Access
Thrill +/-
Heat
Drainage
Swelling
Tenderness
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Post-Dialysis Care
Observe for bleeding from cannulation sites.
Hold pressure if necessary. If not controlled, immediatelynotify the nephrologist and continue to hold pressure.
Remove tape/bandage within 24hrs after dialysis.
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Typical Medications
Vitamins Multivitamins withoutminerals or vitamin D
Phosphate binders
Erythropoietin
Iron
Vitamin D
Antihypertensives
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Typical Medications
Vitamins Multivitamins withoutminerals or vitamin D
Phosphate binders
Erythropoietin
Iron
Vitamin D
Antihypertensives
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Nutrition
Nutrition plays a critical role in the managementof the CKD patient.
The diet will vary depending on the type of
disease, the CKD stage, and the type oftreatment chosen.
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Dietary Considerations
PROTEIN 1.0-1.2g/kg/day 50% high biologic value
POTASSIUM 40-70 mEq (1500-2500mg)/day
SODIUM 750-1000 mg/day
PHOSPHORUS 600-1200 mg/day
CALORIES >35 kcal/kg/day
FLUIDS 1 to 1.5 liters/day plus urine output
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Dietary Considerations
PROTEIN 1.0-1.2g/kg/day 50% high biologic value
POTASSIUM 40-70 mEq (1500-2500mg)/day
SODIUM 750-1000 mg/day
PHOSPHORUS 600-1200 mg/day
CALORIES >35 kcal/kg/day
FLUIDS 1 to 1.5 liters/day plus urine output
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Social Services
Social services are provided topatients and their families and aredirected at supporting and maximizingthe social functioning and adjustment
of the patient.
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Stressors Associated with Dialysis
Actual or threatened loss
Distortion of body image
Dependency on machines and medical team
Fear of death vs. fear of living
Patient self-concept
Capacity to control
Helplessness
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Communication Between Dialysis Center and LTC
Transportation Family Issues
Financial Concerns
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End-of-Life Issues
Assess patient for supportsystems, emotional status,and perceived quality oflife.
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Communication
Treatment Communication
Long-Term Care Plan
Short-Term Care Plan
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Coordination of Laboratory Requirements
CKD patients who receive dialysis in-center will usually have monthly labwork drawn at the dialysis center.
Some tests, such as H/H and
calcium, may be drawn weekly.
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Lab Draw Sites
Specific lab draw sites are chosen for the CKDpatient.
The dialysis staff draws the lab specimen fromthe blood lines during treatment.
For non-dialysis staff: DO NOT performvenipucture from the arm that has the fistulaor graft.
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Chemistry Values Normal for CKD
Bun 21 mg/dL 101 mg/dL
Creatinine 2.5 mg/dL 14.2 mg/dL
Sodium 115 meq/L 160mg/dL
Potassium 3.5meg/L 5.5 mEq/L
Calcium 9mg/dL 11 mg/dL
Phosphorus 4.5 mg/dL 5.5 mEq/L
Glucose 70 mg/dL 110 mg
Albumin 3.5 mg/dL 5.0 mg/dL
Hemoglobin 11g/dL 13 g/dL
Hematocrit 33% 39% (if anemic)
Hepatitis Status Negative for HbSAG Positive for HbSAB
Residual Renal Function May have some, and amount would becollected and calculated into the urinecreatinine clearance equation.
Test Low High
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Chemistry Values Normal for CKD
Bun 21 mg/dL 101 mg/dL
Creatinine 2.5 mg/dL 14.2 mg/dL
Sodium 115 meq/L 160mg/dL
Potassium 3.5meg/L 5.5 mEq/L
Calcium 9mg/dL 11 mg/dL
Phosphorus 4.5 mg/dL 5.5 mEq/L
Glucose 70 mg/dL 110 mg
Albumin 3.5 mg/dL 5.0 mg/dL
Hemoglobin 11g/dL 13 g/dL
Hematocrit 33% 39% (if anemic)
Hepatitis Status Negative for HbSAG Positive for HbSAB
Residual Renal Function May have some, and amount would becollected and calculated into the urinecreatinine clearance equation.
Test Low High
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Chemistry Values Normal for CKD
Bun 21 mg/dL 101 mg/dL
Creatinine 2.5 mg/dL 14.2 mg/dL
Sodium 115 meq/L 160mg/dL
Potassium 3.5meg/L 5.5 mEq/L
Calcium 9mg/dL 11 mg/dL
Phosphorus 4.5 mg/dL 5.5 mEq/L
Glucose 70 mg/dL 110 mg
Albumin 3.5 mg/dL 5.0 mg/dL
Hemoglobin 11g/dL 13 g/dL
Hematocrit 33% 39% (if anemic)
Hepatitis Status Negative for HbSAG Positive for HbSAB
Residual Renal Function May have some, and amount would becollected and calculated into the urinecreatinine clearance equation.
Test Low High
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Chemistry Values Normal for CKD
Bun 21 mg/dL 101 mg/dL
Creatinine 2.5 mg/dL 14.2 mg/dL
Sodium 115 meq/L 160mg/dL
Potassium 3.5meg/L 5.5 mEq/L
Calcium 9mg/dL 11 mg/dL
Phosphorus 4.5 mg/dL 5.5 mEq/L
Glucose 70 mg/dL 110 mg
Albumin 3.5 mg/dL 5.0 mg/dL
Hemoglobin 11g/dL 13 g/dL
Hematocrit 33% 39% (if anemic)
Hepatitis Status Negative for HbSAG Positive for HbSAB
Residual Renal Function May have some, and amount would becollected and calculated into the urinecreatinine clearance equation.
Test Low High
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ReferencesGutch,C.F., et al. (1999). Hemodialysis for nurses and dialysis personnel (6 th ed.). St. Louis, MO: Mosby,
Inc.
McCann, L. (1997). Pocket guide to nutrition assessment of the renal patient(2nd ed.) (pp. 9-15). NewYork: The National Kidney Foundation on Renal Nutrition.
National Kidney Foundation. (2003). Kidney disease outcome quality initiative.
USRDS. (2001).
U.S. Renal Data System. (2003). USRDS 2003 annual data report: Atlas of end-stage renal disease in theUnited States. Bethesda, MD: The National Institutes of Health, National Institute of Diabetes andDigestive and Kidney Diseases.
Youngerman-Cole, S. (2003). End-stage renal disease. Boise, ID: Healthwise, Inc. Retrieved September9, 2003, from http://yalenewhavenhealth.org/library/healthguide/en-us/
support/topic.asp?hwid=aa106246
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Glossary Artificial Kidney (Dialyzer) A device that allows for purification of the blood. During the dialysis
treatment, blood and dialysate flow through the dialyzer separated by a semipermeable membrane.The pores in the membrane allow the removal of waste products and excess fluid.
Dialysate (Bath) Fluid consisting of treated water, electrolytes, and buffers that can be mixed to theindividual patient needs. It passes through the dialyzer to remove waste products and excess water.
Diffusion The movement of a substance from an area of high concentration to an area of low
concentration. Diffusion is the main transport principle for solute (waste products) in hemodialysis
Dryweight The weight a patient is estimated to have with normal blood pressure and no fluidretention.
FistulaA surgically created connection between a patients own artery and vein.
Graft An implant connecting an artery and a vein.
Heparin A drug used in the dialysis treatment to prevent clotting of blood in the dialyzer. Waste Products Substances formed from the breakdown of proteins, nutrients, etc (urea,
creatinine).