Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal...

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Circulation H

Transcript of Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal...

Page 1: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Circulation H

Page 2: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 115Female age 2. Multiple scaly papules back,

abdomen, chest, groin, natal cleft. Scaling scalp

S-100, CD1a, HLA-DR positive.

HMB-45 negative

Page 3: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 4: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 5: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 6: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Langerhan’s cell histiocytosis

Page 7: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 116Female age 81. Biopsy left pre-tibial skin ?

Bowen's.

Page 8: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 9: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 10: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 11: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Porokeratosis

Page 12: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 117Female age 47. Ten year history of post-

traumatic growth on medial left lower leg.

SMA +, Desmin -, S100 -,CD34 -.

Page 13: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 14: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 15: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 16: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 17: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 18: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Fibrous histiocytoma

Page 19: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 118Female age 43 with multiple tan macules

CKit strongly positive in cells in the dermis

Page 20: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 21: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 22: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Cutaneous mastocytosis

Page 23: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 119Female age 57.

5-6 years history of a few slightly warty papules on left thigh and knee. Bleed. ?Trauma.

Page 24: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 25: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 26: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 27: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Clear cell acathoma

Page 28: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 120Male aged 30.

Multiple painful skin nodules.

Page 29: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 30: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 31: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 32: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 33: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Glomangioma

Page 34: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 121Female aged 53.

? BCC ? Jessner's

Page 35: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 36: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 37: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 38: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 39: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Lupus

Page 40: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 122Male aged 48.

Skin biopsy left shin.

Page 41: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 42: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 43: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Hypertrophic lichen planus

Page 44: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 123Female aged 41.

Tumour on face. Several previous facial and scalp tumours.

Page 45: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 46: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 47: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 48: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 49: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 50: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Spiradenoma

Page 51: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Case 124Female aged 23.

Excision lesion right buttock. ? Blue naevus.

Page 52: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 53: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 54: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 55: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 56: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 57: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.
Page 58: Circulation H. Case 115 Female age 2. Multiple scaly papules back, abdomen, chest, groin, natal cleft. Scaling scalp S-100, CD1a, HLA-DR positive. HMB-45.

Preferred diagnosis:

Cellular blue naevus