Cigarette Smoking Increases the Risk Of Formation and Rupture of Intracranial Aneurysms
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Cigarette Smoking Cigarette Smoking Increases the Risk Of Increases the Risk Of
Formation and Rupture Formation and Rupture of Intracranial of Intracranial
AneurysmsAneurysms
Shelebra BartleyShelebra BartleyMaster’s ProjectMaster’s Project
Dr. GrimesDr. Grimes
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If you are a woman with a If you are a woman with a brain and you smoke…brain and you smoke…
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Your brain will EXPLODEYour brain will EXPLODE
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Quick ReviewQuick Review An aneurysm is a weakened spot on An aneurysm is a weakened spot on
a blood vessel that balloons out and a blood vessel that balloons out and fills with bloodfills with blood
The aneurysm can put pressure on The aneurysm can put pressure on surrounding nerves or it can rupture surrounding nerves or it can rupture causing blood to spill into the causing blood to spill into the surrounding tissuesurrounding tissue
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3 Types of Aneurysms3 Types of AneurysmsFusiformFusiformBerry Berry Lateral Lateral
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Berry AneurysmBerry Aneurysm Aka saccular aneurysmAka saccular aneurysm Attached by a neck or a stem to an Attached by a neck or a stem to an
arteryartery Accounts for 90% of all aneursymsAccounts for 90% of all aneursyms
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Berry AneurysmBerry Aneurysm
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How to diagnose an How to diagnose an Aneursym?Aneursym?
CT angiographyCT angiography Magnetic Resonance Angiography Magnetic Resonance Angiography
(MRA)(MRA)
THE GOLD STANDARDTHE GOLD STANDARD INTRA-ARTERIAL CATHETER INTRA-ARTERIAL CATHETER
ANGIOGRAPHYANGIOGRAPHY
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CT Scan Arteriogram
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Treatment OptionsTreatment Options REFERREFER REFERREFER REFERREFER
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EducationEducation Stop smokingStop smoking
Stop drinkingStop drinking
Control blood pressureControl blood pressure
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Helsinki Research ResultsHelsinki Research Results Studied 278 subjectsStudied 278 subjects Age 15-60 with subarachnoid Age 15-60 with subarachnoid
hemorrhagehemorrhage 314 patients in control group314 patients in control group
Research team studied the effects of Research team studied the effects of cigarette smoking, alcohol intake and cigarette smoking, alcohol intake and HTN on the rupture of intracranial HTN on the rupture of intracranial aneurysmsaneurysms
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What they found…What they found… Current cigarette smoking especially in Current cigarette smoking especially in
women is an independent risk factor women is an independent risk factor for formation and rupture of for formation and rupture of intracranial aneurysmsintracranial aneurysms
Current smokers and previous smokers Current smokers and previous smokers had more aneurysms than did those had more aneurysms than did those who had never smoked regularlywho had never smoked regularly
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Johns Hopkins ResearchJohns Hopkins Research Angiography confirmed intracranial Angiography confirmed intracranial
aneurysmsaneurysms 419 patients dx with intracranial 419 patients dx with intracranial
aneurysmaneurysm
127 had multiple aneurysms127 had multiple aneurysms Women and hx of smokingWomen and hx of smoking
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Anybody need a smoke Anybody need a smoke break?break?
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University of ColoradoUniversity of Colorado 92% of patients with aneurysms 92% of patients with aneurysms
larger than 24mmlarger than 24mm
78% of patients with aneurysms 78% of patients with aneurysms ranging in size from 13.3mm to 24mm ranging in size from 13.3mm to 24mm
66% of patients with aneurysms 66% of patients with aneurysms smaller than 13mmsmaller than 13mm
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WEREWERESMOKERSSMOKERS
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IN CONCLUSIONIN CONCLUSION Evidence has shown that cigarette Evidence has shown that cigarette
smoking increases the rate of smoking increases the rate of formation and rupture of intracranial formation and rupture of intracranial aneurysmsaneurysms
Cigarette smoking and female Cigarette smoking and female gender can be identified as an gender can be identified as an independent risk factorindependent risk factor
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If you are a woman with a If you are a woman with a brain and you smoke…your brain and you smoke…your
brain will explodebrain will explode