Chromosomal abnormalties
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Transcript of Chromosomal abnormalties
Types Numerical - change in no.Structural – change in structure
Structural abnormalities1. Translocations2. Deletions3. Insertions 4. Inversions 5. Duplication
Translocation
Segments from two different chromosomes are exchanged
Deletions A portion of chromosome is missing or deleted
DuplicationA portion of chromosome is duplicated
Insertions A segment of chromosome breaks off,and attaches to another chromosome
1.Artificially:
It can be produces by X-irradiation in laboratory, Chromosome break into pieces, these pieces reattach in inverted form.
Morphology of the chromosome will not be change