Chromatography Data System: Expand to the Enterprise
-
Upload
chromsolutions -
Category
Science
-
view
326 -
download
12
description
Transcript of Chromatography Data System: Expand to the Enterprise
2
The world leader in serving science
Streamline Your Laboratory
Thermo Scientific Dionex Chromeleon CDS Seminar
[Enter location and date here]
Expand to the Enterprise
3
Contents
• Introduction• Network Architecture• Centralized Management• Operational Security• Enterprise Tools
4
Introduction
• In laboratory often each instrument is controlled by its own software, especially for more sophisticated instruments like a mass spectrometer (MS)
• This has some disadvantages:• Analysts have to learn multiple software packages
• All actions need to be done on the computer next to the instruments
• Maintenance of multiple software packages
• No central data storage
• Solution: One Chromatography Data System (CDS) for the entire laboratory
5
Thermo Scientific Chromeleon 7 CDS Streamlines Chromatography
For your entire enterprise
6
Network Architecture
7
Key Features for an Enterprise Environment
• Networking capabilities• Central data storage
• Choice of database
• Acquiring data to a central Data Vault
• Network failure protection
• Multiple Instrument Control• Instruments from different vendors
• Centralized Administration• License management, license server
• User management
• Security• User management, access control
• Electronic signatures
8
Key Features for an Enterprise Environment
• Archiving• Transfer of data to a long term archive
• Backup• Securing installation and configuration data
for emergency restore
• Qualification• Installation, Operational and Performance
Qualification
• Both Software and Instruments
• Integration• LIMS, ELN
• Custom tools
9
Chromeleon CDS Domain
Network Capabilities - Client/Server Architecture
LC
LaboratoryWorkstation
IC
Stand-AloneWorkstation
Remote Clientor TS Client
File/Database Server
Citrix / WTS Server
Firewall
InternetMobile Client
LaboratoryWorkstation LC/MS
InstrumentController
Chromeleon Domain Controller (CDC)
VPN
10
Centralized Management
11
Centralized Management – Administration Console
• Centralized management of entire CDS from one location• Easy administration of
• Licenses
• Scheduler
• User accounts
• Discovery
12
Administration Console – License Manager
• Immediate overview of all licenses• Easily reassign licenses, for example when relocating
modules or instruments
13
Administration Console - Scheduler
• Automatically move data by combining powerful injection queries with the Scheduler
• Easily organize your system
14
Administration Console – User Management
• Comprehensive user management tools to define what users can change and/or access
• Ensures integrity and security of your data
15
Administration Console - Discovery
• Easy installation and configuration of enterprise installation: Simply enter Discovery Service location on each PC in Chromeleon Domain
16
Administration Console - Discovery
• All computers in the Chromeleon Domain are automatically connected and configured
• Automatically connects: • Data Vaults
• Data Vault services
• User database
• Instruments
• Instrument Controllers
• Distributes settings for:• User management
• Instrument & Client licensing
• Scheduler (archiving tool)
• Custom ePanels
• User profiles
17
Operational Security
18
Operational Security
• Ensure no data loss due to server crash or network failure• After major server crash, any data stored there can be
restored from backup tapes / images (IT responsibility)• Ensure operation even if the network is down
19
Operational Security – Ensuring Operation
• Ensure software license is available• License information cached on all computers and available for 7 days
• Ensure users can logon• Encrypted user database is cached locally
• Ensure users can continue working• Secure XVault™ infrastructure
• Keep instruments running
• Create and run new sequences
• Keep data generated during network failure accessible for processing
• Ensure no loss of data being generated at point of network failure• Network Failure Protection
20
Typical Chromeleon Enterprise CDS Installation
• Chromatography Instruments are controlled by an Instrument Controller computer.
20
Remote Client
Instrument Controller with XVault
Central Server
XVault
21
Typical Chromeleon Enterprise CDS Installation
• Chromatography data is stored in a Data Vault on a central server.
21
Remote Client
Instrument Controller with XVault
Central Server
XVault
22
Typical Chromeleon Enterprise CDS Installation
• Remote Clients can control the Instruments in the network.• Remote Clients can access the data in the network.
22
Remote Client
Instrument Controller with XVault
Central Server
XVault
23
Chromeleon CDS - Creating a Sequence
• Sequences are created directly in the network Data Vault.• Sequences are visible and editable from everywhere in the
network.
23
Remote Client
Instrument Controller with XVault
Central Server
XVault
24
Chromeleon CDS - Preparing to Start Sequence
• When the sequence is put into the Queue, it is transferred to the secure XVault on the Instrument Controller.
• The sequence is visible and editable from everywhere in the network.
Remote Client
Central Server
Instrument Controller with XVault
XVault
25
Chromeleon CDS - Running Sequence
• When started the sequence runs locally on the Instrument Controller, and data is synchronized with central server.
• The sequence including data is visible and editable from everywhere.
XVault
Remote Client
Instrument Controller with XVault
Central Server
26
Chromeleon CDS - Network Failure
• When the network fails acquisition continues on the secure XVault.
• The sequence including data is visible and editable from the Instrument Controller.
Remote Client
Instrument Controller with XVault
Central Server
XVault
27
Chromeleon CDS - Application Availability
• During network failure it is possible to create and start new sequences from the XVault.
Remote Client
Instrument Controller with XVault
Central Server
XVault
28
Chromeleon CDS - Network Recovery
• When the network is back, data will be transferred back to the central Data Vault.
• The sequence is again visible and editable from everywhere in the network.
Remote Client
Instrument Controller with XVault
Central Server
XVault
29
Enterprise Tools
30
Integration to 3rd Party Software
• Interface with any:• LIMS
• SDMS
• ELN
• or any other 3rd party software package!
• A Software Development Kit (SDK) provides a set of development tools that allows users to create special applications which require direct access to the data.• An example is creating an interface to a LIMS platform to automatically
process worklists in the CDS and for the final result to be posted back into the LIMS
31
Support Documentation
• Complete set of documentation available:• General
• Project Specific
• Database Installation & Configuration
• Software Installation & Configuration
• Installation Checklists
• These documents are designed to cover all compliance & regulatory requirements
32
Summary
33
Summary
• Streamline your laboratory - use one CDS to control all chromatography instruments and process and report all data:• Reduced training effort for the laboratory staff – one single software
package instead of several
• Operate all your chromatographic instruments, including MS, using one software
• Highest laboratory uptime and prevention of data loss through Operational Security and secure XVault infrastructure
• Lower operating cost with centralized management of one single software
34
Summary – Bringing It All Together
Discovery
Security
AdminConsole
All the tools you need to expand your CDSto the enterprise level!
Network
XVault
35
Thank You!
Any Questions?