ChemInform Abstract: Synthesis and Antiinflammatory Activity of Some New...
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1998 ring closure reactions ring closure reactions O 0130 39 - 032 Synthesis and Antiinflammatory Activity of Some New 2-(4- Isobutylphenyl)propionic Acid Derivatives. — The carboxylic acid group of ibuprofen is replaced by an oxadiazole, thiadiazole, and triazole nucleus in the hope of obtaining potential antiinflammatory agents. The results show that compounds (III) and (IV) exhibit higher antiinflammatory activity than ibuprofen (some yields not given). — (AMIR, M.; SHAHANI, S.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 37 (1998) 5, 502-505; Dep. Pharm. Chem., Jamia Hamdard Coll. Pharm., New Delhi 110 062, India; EN) 1
Transcript of ChemInform Abstract: Synthesis and Antiinflammatory Activity of Some New...
1998 ring closure reactions
ring closure reactionsO 0130
39 - 032Synthesis and Antiinflammatory Activity of Some New 2-(4-Isobutylphenyl)propionic Acid Derivatives. — The carboxylic acidgroup of ibuprofen is replaced by an oxadiazole, thiadiazole, and triazole nucleusin the hope of obtaining potential antiinflammatory agents. The results showthat compounds (III) and (IV) exhibit higher antiinflammatory activity thanibuprofen (some yields not given). — (AMIR, M.; SHAHANI, S.; Indian J.Chem., Sect. B: Org. Chem. Incl. Med. Chem. 37 (1998) 5, 502-505; Dep.Pharm. Chem., Jamia Hamdard Coll. Pharm., New Delhi 110 062, India; EN)
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