ChemInform Abstract: A Simple and Convenient High Yielding Synthesis of Substituted Isoindolines.

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ChemInform 2010, 41, issue 34 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Indole derivatives R 0140 DOI: 10.1002/chin.201034131 A Simple and Convenient High Yielding Synthesis of Substituted Isoindolines. — TFAA-induced cyclocondensation of compounds of type (I) yields isoindolines (II). However, cyclohexyl-substituted compounds of type (III) are used as starting material only elimination of water and no cyclocondensation is observed. — (SMITH*, K.; EL-HITI, G. A.; HEGAZY, A. S.; FEKRI, A.; Heterocycles 80 (2010) 2, 941-956, DOI:10.3987/COM-09-S(S)61 ; Sch. Chem., Cardiff Univ., Cardiff CF10 3AT, UK; Eng.) — M. Bohle 34- 131

Transcript of ChemInform Abstract: A Simple and Convenient High Yielding Synthesis of Substituted Isoindolines.

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Indole derivativesR 0140 DOI: 10.1002/chin.201034131

A Simple and Convenient High Yielding Synthesis of Substituted Isoindolines. — TFAA-induced cyclocondensation of compounds of type (I) yields isoindolines (II). However, cyclohexyl-substituted compounds of type (III) are used as starting material only elimination of water and no cyclocondensation is observed. — (SMITH*, K.; EL-HITI, G. A.; HEGAZY, A. S.; FEKRI, A.; Heterocycles 80 (2010) 2, 941-956, DOI:10.3987/COM-09-S(S)61 ; Sch. Chem., Cardiff Univ., Cardiff CF10 3AT, UK; Eng.) — M. Bohle

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ChemInform 2010, 41, issue 34 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim