ChemInform Abstract: A General Palladium-Catalyzed Amination of Aryl Halides with Ammonia.
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ChemInform 2009, 40, issue 35 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Amines Q 0120 A General Palladium-Catalyzed Amination of Aryl Halides with Ammonia. — A new robust palladium/phosphine system allows the selective monoarylation of am- monia with different aryl bromides and chlorides. The active catalyst is formed in situ from Pd(OAc)2 and air- and moisture-stable phosphines as easy-to-handle pre-cata- lysts. The productivity is comparable to that of competitive Pd/phosphine systems. However, in contrast to the previously reported Pd-catalyzed procedures, the effective conversion of halostyrenes, haloindoles, and aminoaryl halides is possible with this system. — (SCHULZ, T.; TORBORG, C.; ENTHALER, S.; SCHAEFFNER, B.; DUMRATH, A.; SPANNENBERG, A.; NEUMANN, H.; BOERNER, A.; BELLER*, M.; Chem. Eur. J. 15 (2009) 18, 4528-4533; Leibniz-Inst. Org. Katal., Univ. Rostock, D-18059 Rostock, Germany; Eng.) — Bartels 35- 075
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Transcript of ChemInform Abstract: A General Palladium-Catalyzed Amination of Aryl Halides with Ammonia.
www.cheminform.wiley-vch.de
AminesQ 0120 A General Palladium-Catalyzed Amination of Aryl Halides with Ammonia. —
A new robust palladium/phosphine system allows the selective monoarylation of am-monia with different aryl bromides and chlorides. The active catalyst is formed in situ from Pd(OAc)2 and air- and moisture-stable phosphines as easy-to-handle pre-cata-lysts. The productivity is comparable to that of competitive Pd/phosphine systems. However, in contrast to the previously reported Pd-catalyzed procedures, the effective conversion of halostyrenes, haloindoles, and aminoaryl halides is possible with this system. — (SCHULZ, T.; TORBORG, C.; ENTHALER, S.; SCHAEFFNER, B.; DUMRATH, A.; SPANNENBERG, A.; NEUMANN, H.; BOERNER, A.; BELLER*, M.; Chem. Eur. J. 15 (2009) 18, 4528-4533; Leibniz-Inst. Org. Katal., Univ. Rostock, D-18059 Rostock, Germany; Eng.) — Bartels
35- 075
ChemInform 2009, 40, issue 35 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
www.cheminform.wiley-vch.de
ChemInform 2009, 40, issue 35 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
