Chapter One

Introduction to Anatomy and Physiology

Relationship Between Anatomy and Physiology

Anatomy: study of the structure and shape of the body and their relationship to one another

Physiology: study of how the body and its parts work or function

STRUCTURE DETERMINES FUNCTION

• Anatomy can be divided into gross and microscopic:– Forms of Gross Anatomy• Surface anatomy – study of superficial marking• Regional anatomy – study of specific area• Systemic anatomy – study of system• Developmental anatomy – study changes from conception

to physical maturity.– Microscopic anatomy includes two major subdivisions• Cytology – study of cell• Histology – study of tissue

The Specialties of Anatomy

Comparative Anatomy

• All vertebrates share a basic pattern of

organization, most noticeable during

embryology.

• Physiology is the study of the normal function of cell, tissue, organs, systems and organisms

• Physiology can be divided into the following specialties:– Cell physiology – study of cell– Special physiology - study of specific organ– Systemic physiology – study of system– Pathological physiology – study of the effect of

disease on cell, tissue, organ and system.

The Specialties of Physiology

Levels of Organization

Organ Systems

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Characteristics of Life

1.Responsiveness a. permits an organism to sense, monitor, and respond to changes in its

external environmentb. highly developed in nerve and muscle cells

2.Conductivity

a. capacity of living cells and tissues to selectively transmit or propagate

a wave of excitation from one point to another within the bodyb. highly developed in nerve and muscle cells

3.Growth a. normal increase in size or number of cellsb. produces an increase in size (person, organ, part)c. little change in the shape

4. Respirationa. Involves processes in absorption, transport, utilization, or

exchange of respiratory gases between an organism and its environment

b. Internal vs. external

5. Digestiona. Complex food products are broken down into simpler substances

that can be absorbed and used by organism

6. Absorptiona. Movement of digested nutrients through the wall of the digestive

tube and into body fluids for transport to cells

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7.Secretion a. Production and delivery of specialized substances (digestive juices, hormones) for diverse body

functions

8.Excretiona. Removal of wastes produced during body functions

(breakdown and use of nutrients in the cell)

9.Circulationa. Movement of body fluids and many other substances

(nutrients, hormones, waste products) from one body area to another

10.Reproductiona. Formation of new individual and new cells (cell

division)b. Permits growth, wound repair, and replacement of

dead/aging cells

What is Metabolism?

• Metabolism – describes the various processes by which life is made possible

- breakdown of nutrients - produce energy- transform one material into

another- required to make complex carbs

out of simple carbs

How can you remember the list?

• I am walking to McDonalds (movement)• I stop at the traffic light (response)• My body is growing (growth)• I am breathing air (respiration)• My body absorbs the hamburger (absorption)• The hamburger circulates in my body (circulation)• The hamburger is changed to things my body needs

(assimilation)• Eventually, I go to the bathroom (excretion)• Someday I may reproduce (reproduction)

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Anatomical Position/Bilateral Symmetry

Anatomical Position – erect; palms, head and feet forward

Bilateral Symmetry – right and left sides are mirror images

General Organization

• Axial= Head, neck, trunk• Appendicular= Arms and legs

Regional Terms

Anterior: front

Posterior: back

Directional Terms

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Directional Terms

Superior – toward the headInferior – toward the feetAnterior/ventral – frontPosterior /dorsal– backMedial – toward the midlineLateral – toward the side/away from midlineProximal – toward or nearest the trunk or

point of originDistal – away from or farthest from trunk or

point of originSuperficial – nearest the surfaceDeep – farther away from surface

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Body Planes

Sagittal – lengthwise, front to back, divides body into left and right sides,

* Midsagittal (sagittal section in middle)

Coronal/Frontal – lengthwise, side to side, divides body into anterior and posterior portions; frontal plane

Transverse – crosswise, divides body or parts into upper and lower parts; horizontal plane

• Body cavities are internal chambers holding vital organs– Cavities protect vital organs– Cavities allow organs to change in shape and size

• Two body cavities– Dorsal body cavity (back side) includes the cranial

cavity and the spinal cavity– Ventral body cavity (front side) includes the thoracic

cavity (chest) and the abdominopelvic (stomach and lower abdomen) cavity

Body Cavities

Body Cavities

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Abdominopelvic Regions4 Quadrants

Doctors divide torso into quadrants to describe the site of pain and/or locate internal pathology (tumor)

1. Right upper quadrant (RUQ)

2. Left upper quadrant (LUQ)

3. Right lower quadrant (RLQ)

4. Left lower quadrant (LLQ)

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Abdominal RegionsSuperficial Organs

1. Right hypochondriac – right lobe of liver, gallbladder

2. Epigastric – right and left lobes of liver, stomach2. Left hypochondriac – stomach, large intestine

3. Right lumbar – large and small intestine5. Umbilical – transverse colon, small intestine

6. Left lumbar – small intestine, colon7. Right iliac – cecum, small intestine

8. Hypogastric – small intestine, bladder, appendix9. Left iliac – colon, small intestine

Homeostasis• Homeostasis is a stable internal environment

• Every organism must maintain homeostasis for survival

• Homeostatic regulation is responsible for keeping internal environment within certain limits.

• Internal environment (ie. body temp, pH, glucose level)• External environment (ie. Weather, fluid surrounding cells)

Two general points:

• Autoregulation or intrinsic regulation – results when cell, organ

or system adjusts its activity automatically.

• Extrinsic regulation - results from activity of nervous system or

endocrine system

• A homeostatic regulatory mechanism consist of :– A receptor – senses an environmental change or

stimuli.– A control center –processes information supplied by

receptor and generates a response (command)– An effector – an organ or cell that responds to the

command of control center.• A variation outside the desired range triggers an

automatic response to correct the situation– Negative feedback

Homeostatic regulation involves

Afferent= approaches

Efferent= exits

Negative Feedback

• Chief regulators of homeostasis under normal, healthy conditions.

• A rise in any given value creates a reaction to lower it until it becomes too low– This causes negative feedback to initiate

responses to raise it again.• Negative does not mean ‘bad’, it just means

that the actions stops.

Negative Feedback: The Control of Body Temperature

Negative feedback: system is shut off

•In positive feedback an initial stimulus produces a response that enhances the change in the original condition. For instance:

• Damage to blood vessel wall will cause release of chemicals.

• Chemicals will trigger blood clotting

• Clotting process increases release of chemicals

• More chemicals means accelerated clotting

• Accelerated clotting means more chemicals

Positive Feedback: Blood Clotting

Positive feedback: reaction continues at a faster rate

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Negative Feedback

• Inhibitor

• Oppose change by creating response opposite in direction of initial disturbance change – temperature drop response – heat production initial disturbance – temp fall below normal set point

• Stabilize physiological variables

• Maintain constant internal environment

•Ex: goosebumps, sweating

Positive Feedback

• Stimulatory

• Amplifies/reinforces change which can be harmful and disastrous

• Cause instability and disrupt homeostasis (continuous temp increase)

• Ex: sneezing, birth of baby, immune response to infection, blood clot