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Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated...
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Transcript of Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated...
![Page 1: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/1.jpg)
Chapter 8-Muscular System
![Page 2: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/2.jpg)
Case Study # 1
Signs and Symptoms:- Respiratory Acidosis
- Accelerated oxygen consumption
- Extreme heat production
Case Study # 2
Signs and Symptoms:- Muscle weakness
- Easily fatigued
- Muscles eventually cease to function
Case Study # 3
Signs and Symptoms:- Uncoordinated
movements
- Jerky to-and-fro motion of trunk and limbs
![Page 3: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/3.jpg)
Three Types of Muscle Tissue
1) Skeletal Muscle- Striated- Voluntary
2) Cardiac Muscle- Striated- Involuntary
3) Smooth Muscle- Non-striated- Involuntary
![Page 4: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/4.jpg)
Functions of Muscular Tissue
1) Produce body movements
2) Stabilize body positions
3) Store and move substances within the body
4) Produce heat
![Page 5: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/5.jpg)
![Page 6: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/6.jpg)
Skeletal Muscle Tissue
- Each muscle is a separate organ
- Composed of thousands of cells → muscle fibers
- Fibers packed in fascicles
![Page 7: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/7.jpg)
Connective Tissue
- Between Skin and Muscle → Hypodermis- Areolar connective tissue- Adipose tissue
- Individual muscles surrounded by Fascia- Dense irregular connective tissue- Supports muscles- Helps form tendons
![Page 8: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/8.jpg)
Connective Tissue
- Epimysium: surrounds whole muscle
- Perimysium: surrounds fascicle
- Endomysium: surrounds muscle fibers
All 3 extend beyond muscle to form a tendon
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Nerve and Blood Supply
- Need A LOT of nutrients and oxygen
- Need to get rid of waste
- Each muscle fiber is in close contact with capillaries and neurons
![Page 10: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/10.jpg)
Skeletal Muscle Histology
![Page 11: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/11.jpg)
- Sarcolemma: plasma membrane
- Sarcoplasm: inner material of fibers (like cytoplasm)- Contains A LOT of mitochondria
- Sarcoplsmic reticulum: fluid-filled tubules that store calcium (like SER)
- Myofibrils: made of protein filaments that extend along length of fiber
The Muscle Fiber (Cell)
![Page 12: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/12.jpg)
Skeletal Muscle Histology
![Page 13: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/13.jpg)
Myofibrils
- Two types of Myofilaments (proteins):1) Actin → Thin filaments2) Myosin → Thick filaments
- Overlap to form light and dark bands
![Page 14: Chapter 8-Muscular System. Case Study # 1 Signs and Symptoms: -Respiratory Acidosis -Accelerated oxygen consumption -Extreme heat production Case Study.](https://reader036.fdocuments.in/reader036/viewer/2022062314/56649e3c5503460f94b2eb32/html5/thumbnails/14.jpg)
Sarcomere
- The basic functional unit of contraction
- Thin filaments (actin) anchored to Z disc
- Thick filaments (myosin) bind to thin filaments at myosin-binding site
Z disc Z disc
Sarcomere
Z discZ disc
Sarcomere
(b) Myofibril
Thin filament
Thick filament
Thin filamentThick filament
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Actin and Myosin
Myosin tail
Myosin
Myosin heads
Myosin-binding site (covered by tropomyosin)
Actin Troponin Tropomyosin
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Fasicles
Fibers
Myofibrils
Actin Myosin