Chapter 5 Lesson 2 Human Genetic Disorders Homework Documents...Chapter 5 Lesson 2 Human Genetic...
Transcript of Chapter 5 Lesson 2 Human Genetic Disorders Homework Documents...Chapter 5 Lesson 2 Human Genetic...
Chapter 5 Lesson 2 Human Genetic Disorders
Ms. Schreurs
7th Grade Life Science
Cells and Heredity
My Planet Diary
Doggie Diagnosis
Page 140
How Are Genetic Disorders Inherited in Humans?
• ___________________= an abnormal condition that a person inherits through genes or chromosomes – Can be caused by:
1. ___________________________________
2. Changes in the overall structure or number of chromosomes
Cystic Fibrosis • Genetic disorder in which the body
produces abnormally thick mucus in the lungs and intestines – Makes it hard for the
person to breathe
– ________________ ________________
– 3 bases have been removed from a DNA molecule
http://www.cbsnews.com/video/watch/?id=4615368n
Sickel-Cell Disease • Causes sickle-shaped red blood cells
that cannot carry as much __________ and can clog vessels – Trait is codominant (S= sickle-cell trait, A=
normal) • Will produce both types
of cells (AS)
– Must have ______ sickle-cell alleles (SS) to have disease
Figure 1 on Page 141
Hemophilia • Genetic disorder in which a
person’s blood clots very ____________________ – Caused by a recessive allele
on the _____ chromosome
– Sex-linked disorder (occurs more frequently in males than in females)
Figure 2, Page 142 (Interactive Art)
Down Syndrome • Person’s cells have an extra copy of
______________________ – Occurs when chromosomes fail to separate
properly during ___________
– Have some degree of mental retardation, and heart defects are also common
Chapter 5 Lesson 2 Human Genetic Disorders
(Continued)
Ms. Schreurs
7th Grade Life Science
Cells and Heredity
How Are Genetic Disorders Traced, Diagnosed, and Treated?
#1- _________________
• = a chart or “family tree” that tracks which members of a family have a particular trait
• Can be an ordinary trait (eye color) or a __________________________
Apply it, page 143
#2- Karyotypes
• = ____________________________ ______________________________
• Determines if a person has the correct number of chromosomes in their cells
Is this a normal or abnormal karyotype?
#3- Genetic Counseling
• Genetic counselors help couples understand their chances of having a child with a particular ______________________ – Use karyotypes, pedigrees, and punnett squares
Dealing with Genetic Disorders • ____________________ help people
with symptoms of some disorders - Example: folic acid (a vitamin) for people with sickle-cell
• Education and job training programs help people with genetic disorders find work
Family Puzzles Cystic Fibrosis
Ian is Joshua and Bella’s son, they want to know the probability of their future children having cystic fibrosis
-Draw a pedigree representing this information -Fill in the family’s genotypes (Cystic fibrosis is
inherited through a recessive allele, the letter N will represent the dominant allele, n will represent the
recessive allele)
Colorblindness
Family Puzzles
Jack and Jill have a son Joe who is colorblind, and a daughter Jess who is not colorblind, neither Jack or Jill are colorblind.
Joe marries Miranda who is not colorblind. Joe and Miranda have two children a daughter Melissa and a son Morgan who are both
colorblind.
1. Draw a pedigree to show this family’s inheritance of colorblindness, use the key to fill in the pedigree
2.Fill in the Genotypes of all the family members on the pedigree
3. If Joe and Miranda have another child, what is the probably it will not be colorblind?
XCXC
XCY
XCXc
XcXc or XcY
Trisomy X
This occurs when a female is born with 3 X chromosomes, draw a complete Karyotype showing this chromosomal
disorder.
Triple X syndrome most often causes no unusual physical features or medical problems.
Triple X syndrome occurs in around 1 in 1,000 girls. On average, five to ten girls with triple X syndrome are
born in the United States each day