Chapter 16 Obj 01
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Transcript of Chapter 16 Obj 01
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16.1GeneralConceptsinImmunity
Explainthebasicaspectsofinnate(nonspecific)andadap?ve(specificoracquired)immunity.
• Whatarethefirstlinesofdefenseagainstpathogens?
• Whatarethesecondlinesofdefense?
• Whatisthethirdlineofdefenseinthebody?
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ThreeLinesofDefenseintheHumanBody
• Innateimmunity1st:Barriersatbodysurfaces–external• Integument&mucousmembranes• Chemicalsecre?ons• microflora
• 3rd:Adap?veimmunity:specificimmuneresponses– Cell‐mediated– An?body‐mediated
2nd:Nonspecificresponses–internal
• Phagocy?ccells• Inflamma?on&fever
• An?microbialproteins
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InnatevsAdap?ve
• Innate–Nonspecific– ATributeswehaveatbirth– Defendusfromallpathogens
• Adap?ve–Acquired–Specific– Notpresentatbirth– ImmuneresponsesthatdevelopaWerexposure
• Vaccine,subclinicalinfec?on,clinicalinfec?on– Uniquecellsforeachspecificpathogen