Challenges to the systematic review of sexual health interventions for people with severe mental...
18
Challenges to the systematic review of sexual health interventions for people with severe mental illness Dr Eva Kaltenthaler Reader in Health Technology Assessment ScHARR, University of Sheffield Co-authors: Abdullah Pandor, Ruth Wong 03/07/22 © The University of Sheffield
-
Upload
scharr-heds -
Category
Healthcare
-
view
149 -
download
2
description
Presentation delivered by Eva Kaltenthaler at HTAi 2014 in Washington D.C. co-authors Abdullah Pandor and Ruth Wong
Transcript of Challenges to the systematic review of sexual health interventions for people with severe mental...
Challenges to the systematic review of sexual health
interventions for people with severe mental illness
Dr Eva KaltenthalerReader in Health Technology AssessmentScHARR, University of Sheffield
Co-authors: Abdullah Pandor, Ruth Wong
11/04/23 © The University of Sheffield
11/04/23 © The University of Sheffield
2
Outline of presentation
• Background
• Issues we encountered
• Some suggestions for future research
Background• People with severe mental illness may
be more likely to engage in high risk sexual behaviour
• At risk of worse sexual health outcomes than the general population
• Rapid systematic review
• Transferability of evidence to the UK setting
11/04/23 © The University of Sheffield
3
11/04/23 © The University of Sheffield
4
BackgroundHeadline results•13 RCTs studies
•People with mental illness
•All trials in USA
•Insufficient evidence to support or reject interventions
•More details in Abdullah’s presentation
The issues
11/04/23 © The University of Sheffield
6
Population
Interventions
11/04/23 © The University of Sheffield
7
• Wide range of interventions: HIV prevention and risk reduction Sexual assertiveness Cognitive behavioural skill building Social skills intervention
• Little detail was provided in the studies regarding the content of interventions, how they were delivered and by whom
Comparators
11/04/23 © The University of Sheffield
8
Outcomes
11/04/23 © The University of Sheffield
9
Other important issues
• UK care pathway likely to be very different from that in the USA
• Some of the studies were quite old-how do we combine data from studies from different time periods?
11/04/23 © The University of Sheffield
10
What can be done differently?
Reporting of studies
• More details regarding intervention components and delivery
• Patient characteristics including diagnosis, co-morbidities etc.
11/04/23 © The University of Sheffield
12
Some trial recommendations• Patient selection criteria clearly
defined
• Clear descriptions of interventions and comparators
• Reliable and valid outcomes with alternatives to self-reported outcomes
11/04/23 © The University of Sheffield
13
Reviewing suggestions
• Contact authors for more study details
• Consider other approaches to reviewing such as realist synthesis
• Incorporate other study designs apart from RCTs
11/04/23 © The University of Sheffield
14
Summary
• Results make it difficult to generalise these findings to the UK setting
• These suggestions may help to ensure that further trials provide more useful information
11/04/23 © The University of Sheffield
15
11/04/23 © The University of Sheffield
Funding Acknowledgement:This project was funded by the National Institute for Health Research HTA (project number 12/74/01)
Department of Health Disclaimer:The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the HTA, NIHR, NHS or the Department of Health.
ReferenceKaltenthaler E, Pandor A, Wong R. The effectiveness of sexual health interventions for people with severe mental illness: a systematic review. Health Technol Assess 2014;18(1) http://www.journalslibrary.nihr.ac.uk/hta/volume-18/issue-1
11/04/23 © The University of Sheffield
17
11/04/23 © The University of Sheffield
18
Thank you!
Email: [email protected]: @evakaltenthalerBooth 7
![Interventions for preventing critical illness ... · [Intervention Review] Interventions for preventing critical illness polyneuropathy and critical illness myopathy Greet Hermans2,](https://static.fdocuments.in/doc/165x107/5f804b24e9ab6257b4401362/interventions-for-preventing-critical-illness-intervention-review-interventions.jpg)
