CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of...

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CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

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Page 1: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences.

CERVICAL/VAGINAL CYTOLOGY

N. Shayanfar MD

Associate Professor of Pathology

Tehran University of Medical Sciences

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INTRODUCTION&HISTORY

Dr.George N.Papanicolaou(1883-1962) Dr.Aurel A.Babes 1927 Dr.George Papanicolaou&Dr.Herbert

F.Traut 1943

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Microscopic Anatomy

Vagina:Non-Keratinizing Stratified Squamous Cervix:

Ectocervix:Non-Keratinizing Stratified Sqamous

Endocervix:Tall Columnar Epithelium �ُSquamocolumnar Junction

Original

Transformation zone

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ASSESSMENT OF QUALITY OF SMEARS

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THE BETHESDA SYSTEM

Statement of specimen adequacy Epithelial cell abnormalities Others

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ADEQUACY OF THE SPECIMEN

Satisfactory for evaluation

Unsatisfactory

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Epithelial cell abnormalities

Low grade intraepithelial lesion(LSIL)

-CIN1(mild dysplasia) & HPV changes High grade intraepithelial lesion

-CIN2,CIN3,CIS(carcinoma insitu)

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LSIL

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LSIL,HPV changes

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HSIL


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