Achieve measurably better healthcare performance.

CHOOSE TRANSFORMATION TM

GET IT RIGHT THE FIRST TIME

CELL-DYN Ruby HEMATOLOGY ANALYZER

www.corelaboratory.abbott/hematology

CELL-DYN Ruby

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CELL-DYN EMERALDCELL-DYN Ruby

First Pass Efficiency. Getting It Right the First Time.

• Screens are straightforward, intuitive and easy to navigate

• Features customizable views• Quickly set up or change many analyzer options

based on laboratory need or protocols

OPERATIONAL EFFICIENCY FLEXIBLE AND EASY-TO-USE• Offers 35 minutes of walkaway time with load

up of 50 specimens• Accommodates tubes of various sizes in open

and closed modes • Integrates with AlinIQ AMS and other popular

middleware packages

• Only 3 reagents required for CBC with differential

• Real-time reagent status monitoring• RFID reagents work with AlinIQ Inventory

Management System (IMS)

REAGENT MANAGEMENT SINGLE-USE RETICULOCYTE OPTION

• Cost-effective stability until printed expiry date on package

• Reagent is available in 100 test package• No refrigeration required

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CELL-DYN Ruby

Enhanced first pass efficiency with MAPSSTM technology

MAPSSTM LASER TECHNOLOGY A HIGHER LEVEL OF INTERROGATION• Analysis performed on up to 10,000 cells from a

single dilution, using a single reagent• Captures up to 40,000 data points

MAPSSTM RESULTS ARE DISPLAYED IN MULTIPLE ELEGANT, COLOR-CODED SCATTERPLOTS• Discriminates between neutrophils, eosinophils,

basophils, monocytes and lymphocytes• Identifies and flags immature cells and interfering

substances

HIGHLY DISCRIMINATE, SEQUENTIAL SEPARATION USING MAPSSTM TECHNOLOGY

1. MononuclearPolymorphSeparation

PSSDSS

IAS

ALL

FOCUSED LASER BEAM

VARIOUS ANGLES OF SCATTERED LIGHT

SAMPLE STREAM

MAPSS™ (MULTI-ANGLE POLARIZED SCATTER SEPARATION) TECHNOLOGY PROVIDES LASER-ACCURATE OPTICAL READINGS FOR WBCs AND DIFFERENTIALS • Axial Light Loss (ALL) provides total count and size of each

cell• Intermediate Angle Scatter (IAS) indicates complexity of

intracellular structure• Polarized Side Scatter (PSS) provides details on granularity

and nuclear lobularity, separating mononuclear from polymorphonuclear cells

• Depolarized Side Scatter (DSS) separates neutrophils from eosinophils

COMPLEXITY

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How MAPSS™ differentiates and classifiesSize Complexity Lobularity Granularity Classification

Cell 0° 10° 90° 90° Depolarized 1st 2nd 3rd 4th

1 165 162 116 32 POLY NEU – –

2 60 64 15 6 MONO – – LYM

3 140 79 21 99 MONO – – MONO

4 148 182 104 118 POLY EOS – –

5 90 110 28 8 MONO – BASO –

Mononuclear Polymorph Separation

Basophil Lymphocyte Monocyte Separation

Neutrophil Eosinophil Separation

Display of 5 Normal WBC Populations

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CELL-DYN EMERALDCELL-DYN Ruby

Two-dimensional Optical Platelet (PLT) Analysis

REPORTABLE PLATELET COUNTS ACROSS A WIDE VARIETY OF ABNORMAL CONDITIONS• First Pass two-angle analysis separates the PLT and RBC populations• Reduces interference from microcytic RBCs, schistocytes and non-platelet particles• Obtain reportable results in the presence of giant or clumped PLTs and on thrombocytopenic samples

without reflexing or extra reagents

IAS (Complexity)

First Pass Optical Platelet Count: Platelets and RBCs are accurately sized and counted by multidimensional laser light scatter. Whole blood is diluted into a proprietary reagent system that optimizes the separation of platelets and RBCs, spheres the RBCs and reduces interference by microcytic red cells and non-platelet particles.

Three-dimensional Optical Red Blood Cell (RBC) AnalysisIMPROVES THE ACCURACY OF RED CELL MEASUREMENTS, INCLUDING RETICULOCYTES• Comprehensive cell-by-cell measurements with readings taken at 0º, 10º and 90º by light scatter detectors enable

exquisite accuracy of RBCs and reticulocytes• Reticulocyte assay based upon NCCLS/ICSH methods

Red cell size and size distributions are displayed using a histogram constructed from the cell-by-cell volume calculated using the 0°, 10° and 90° light scatter measurements of each sphered red blood cell.

ALL (Size)

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CELL-DYN Ruby

Four-dimensional White Blood Cells (WBC) AnalysisWBCs ARE COUNTED AND CLASSIFIED SO THAT RESULTS CAN BE REPORTED ON THE FIRST RUN, EVEN WHEN ABNORMAL CELLS AND INTERFERING SUBSTANCES ARE PRESENT• Reduce manual reviews due to interference from NRBCs, clumped platelets and debris• MAPSSTM technology can detect potential interference from lysis-resistant RBCs; the flagged samples can be re-run

in the lysis-resistant mode without microscopic review (Figure 1 and 2)

Neutrophils and eosinophils are separated from lymphocytes, monocytes and basophils by differences in their complexity and lobularity.

Neutrophils are separated from eosinophils by virtue of their different characteristics in scattering polarized (PSS) and depolarized (DSS) light.

Basophils are separated using both size (ALL) and complexity (IAS) readings, allowing lymphocytes and monocytes to be separated by size (ALL) information.

The net result of the simultaneous laser scatter readings is excellent discrimination among the 5 normal cell populations.

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IAS

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ALL (Size)

Figure 1: The occurrence of a significant population of cells occurring below the dynamic WBC Optical Count (WOC) threshold can suggest the presence of lysis-resistant RBCs.

Figure 2: In cases where lysis-resistant RBCs occur, the sample is re-run in the resistant RBC mode to provide the 5 part differential.

COMPLEXITYCOMPLEXITY

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CELL-DYN Ruby

Touch-Screen Convenience & Flexibility With Multifaceted Software

QUALITY CONTROL• Users can store up to 500 quality control files• Multiple Westgard Rules are available to select from• Moving averages available for RBC, WBC,

differential, PLT, and reticulocyte parameters

USER-FRIENDLY SOFTWARE PACKAGE• Context-sensitive help menus• Calibration wizard• On-board maintenence videos available• Software available in multiple languages

ENHANCE WORKFLOW EFFICIENCY WITH QC MANAGEMENT, USER-DEFINABLE DECISION RULES, SMART SOFTWARE FEATURES AND ABBOTTLINK

INCREASE OPERATIONAL EFFICIENCY

Harmonize Laboratory Data With AlinIQ AMS Middleware

With AlinIQ AMS (Analyzer Management System) middleware, you can standardize operations across your laboratory system to increase resource utilization. AlinIQ AMS is an open, scalable solution that can connect virtually any analyzer or automation system to the LIS to better manage the flow of data throughout the entire workflow process.

AlinIQ AMS FUNCTIONALITY

• Test Management: Hematology results views and advanced autoverification rules for consistent results management

• Sample Management: Monitor steps in the sample workflow and tube logistics between facilities• Historical Reports: Better understand and manage laboratory performance• Equipment Management: Centralize the monitoring and control of analyzers and automation systems• Quality Management: Tools designed to help with ISO 17025 compliance

AbbottLink® DRM• AbbottLink® is a Device Relationship Management

system that allows Abbott to gather system data• Data is encrypted and transferred over the internet to

help improve the troubleshooting process

DATA MANAGEMENT• Rules-based result annotations allow you to standardize

lab processes to meet your laboratory’s needs• Program up to 100 rules and up to 48 result annotations

to help streamline your data management processes

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CELL-DYN EMERALDCELL-DYN Ruby

SPECIFICATIONS DESCRIPTIONSProduct InformationThroughput CBC + Differential up to 84 per hourSample Size Open mode ≤ 150 µL, Sample Loader ≤ 230 µLReagents Only 3 reagents plus optional reticulocyte reagent

TechnologyWBC and Differential Optical MAPSSTM Multiple Scatterplot Analysis

RBC and Platelet Optical analysis with no additional reagent or reflex testing requirement for PLTs

Reticulocyte Optical analysis with New Methylene Blue NCCLS method, supravital staining technique

PARAMETERSWhite Cells Red Cells PlateletsWBC RBC RDW PLT

NEU # and % HGB RETIC MPV

LYM # and % HCT PCT*

MONO # and % MCV PDW*

EOS # and % MCH *Clinical significance has not been established for PCT and PDW. Therefore, they are not reportable in the US.BASO # and % MCHC

ANALYTICAL MEASUREMENT RANGESParameter AMR Units

WBC 0.02 – 246.8 x 103/µLRBC 0.00 – 7.50 x 106/µLHGB 0.0 – 25.0 g/dLHCT 8.3 – 79.8 %MCV 58 – 139 fLRDW 10.0 – 29.8 %PLT 0.00 – 3000 x 103/µLMPV 4.3 – 17.2 fLRETIC 0.2 – 22.9 %

CELL-DYN Ruby is a Class 1 laser product. For in vitro diagnostic use only. Refer to the Operator’s Manual for operational precautions, limitations, and hazards.  Manuals may be found on the www.corelaboratory.abbott website.CELL-DYN Ruby, AlinIQ, AbbottLink and CHOOSE TRANSFORMATION are trademarks of Abbott Laboratories in various jurisdictions. © 2020 Abbott Laboratories. ADD-00056700

Achieve measurably better healthcare performance. CHOOSE TRANSFORMATION™

www.corelaboratory.abbott/hematology

ELECTRICAL REQUIREMENTS

Module Voltage Frequency Max current Max power consumption

Analyzer 100 – 240 VAC 50/60 Hz 5.0 – 2.2 amps 550 watts

Display 100 – 240 VAC 50/60 Hz 1.5 amps 50 watts

SYSTEM MEASUREMENTSModule Height Width Depth Weight

Analyzer 49.9 cm (19.25 in.)

86.4 cm (34.0 in.)

76.8 cm (30.25 in.)

105.2 kg (232.0 lbs.)

Printer Refer to the printer manufacturer’s specifications

DATA MANAGEMENTMicrosoft Windows based Operating System Rules-based result annotations• Decision rules• Up to 100 rules• Up to 48 result annotations• Fully customizableTouch Screen MonitorFull on-board QC• Summary statistics and Levey-Jennings plots• Moving averages (including WBC differential) • Westgard rules10,000 results stored with graphicsWork list capabilityProgrammable patient and report limitsComplete patient demographicsBar code reading: Code 39, Codabar, Code 128, Interleaved 2 of 5, ISBTAuto-calibration online guideOn-board diagnostics and help videosOPERATING ENVIRONMENT TEMPERATURE15°C (59°F) to 30°C (86°F)HUMIDITY≤ 80 % relative humidity, non-condensing indoor useSTANDARDS & SAFETY COMPLIANCE• UL 61010-1• CAN/CSA-C22.2 No. 61010-1• ETL • CE Mark

• IEC 61010-1• IEC 60825-1• IEC 61326-1• IEC 61325-2-6

ORDERING INFORMATION• 08H67-01 CELL-DYN Ruby analyzer• 09H04-03 Accessory kit (RoHS)• 08H02-06 19” Touch screen flat panel display• 08H14-01 Membrane keyboard

Rx Only