Cell and subcellular structures ppt BIOCHEMISTRY
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Transcript of Cell and subcellular structures ppt BIOCHEMISTRY
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Dr. Vijay Marakala, MBBS, MD.
Assistant professor BIOCHEMISTRY SIMS & RC
CELL AND SUBCELLULAR STRUCTURE
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CONTENT
Introduction Cell membrane
Subcellular organelles
Membrane Transport
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CELL
Structural and
functional unit of life
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Major components
Cell membrane
Cytoplasm with organelles
Nucleus
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Animal Cell
Cell wall
Nucleus
Mitochondria
Endoplasmic Reticulum
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Plant Cell
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PROKARYOTES – NO WELL DEFINED NUCLEUS
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CELL MEMBRANE (PLASMA MEMBRANE)
• Chemical composition
Lipids
Phospholipids
Glycolipids
Cholestrol
Proteins
Integral proteins
Peripheral proteins
Carbohydrates
Glycoproteins
Glycolipids
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FLUID MOSAIC MODEL OF CELL MEMBRANE
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MEMBRANE LIPIDS
Phospholipids
Glycolipids Cholesterol
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MOST MEMBRANE LIPIDS ARE AMPHIPATHIC HAVING NONPOLAR END AND POLAR END.
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MEMBRANE PROTEINS
Integral proteins
Peripheral protein
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MEMBRANE CARBOHYDRATES • Play a key role in cell-cell recognition– ability of a cell to distinguish one cell from
another• antigens
– important in organ & tissue development
– basis for rejection of foreign cells by immune system
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CELL MEMBRANE
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DISORDER OF MEMBRANE TRANSPORT PROTEIN
Defect in Cystic fibrosis transmembrane regulator (CFTR) protein
A Cl
transporter
Cystic Fibrosis
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STUDY QUESTIONS
Describe the Fluid mosaic model of Cell membrane.
Describe the composition of Cell
membrane.
Describe the functions of plasma
membrane.
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