Celiac disease
description
Transcript of Celiac disease
![Page 1: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/1.jpg)
CELIAC DISEASE
![Page 2: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/2.jpg)
What is Celiac Disease? An autoimmune disease where the
protein gluten damages the villi in the small intestine causing malabsorption.
Celiac Disease is a lifelong condition.
Celiac Disease is also called celiac sprue, nontropical sprue, and gluten sensitivity enteropathy
![Page 3: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/3.jpg)
What is gluten?
Protein found in barley, rye, and wheat
(includes spelt, kamut, and triticale)
![Page 4: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/4.jpg)
What causes Celiac Disease?
Immune system overreacts to gluten
Inflammation of mucosa in small intestine
Unknown cause, still being researched
![Page 5: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/5.jpg)
What are the symptoms?
Classic Symptoms Abdominal distention/Bloating Diarrhea Stomach cramps Gas Constipation Fatty stools
![Page 6: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/6.jpg)
What are the symptoms (cont.)
Fatigue Joint pain Bone loss Depression Weight loss Neuropathy
Skin rash Mouth ulcers Missed menstrual
cycles Infertility
Less Obvious Symptoms
![Page 7: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/7.jpg)
Symptoms in Children Diarrhea or constipation (or both) Failure-to-thrive Stunted growth Poor appetite or food aversion Vomiting Abdominal distention or bloating Fatigue and irritability Weight loss Iron deficiency anemia Behavior changes Enamel defects of permanent teeth Delayed puberty
photo courtesy of Columbia University
![Page 8: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/8.jpg)
How common is Celiac Disease?
1 in 133 people are diagnosed with Celiac Disease
97% of people with Celiac Disease are not diagnosed!
Prevalence of Celiac Disease has increased in the past 50 years
Can be misdiagnosed as IBS, Crohn’s, Inflammatory Bowel Disease, parasitic infection, or other bowel disorder
![Page 9: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/9.jpg)
Who is at risk?Those diagnosed with: Type 1 Diabetes Autoimmune Thyroid condition Rheumatoid Arthritis Sjögren’s Syndrome Addison’s disease Down syndrome Microscopic colitis Autoimmune liver disease or hepatitis
![Page 10: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/10.jpg)
How is Celiac Disease diagnosed?
Endoscopy with Intestinal Biopsy
Specific antibody blood tests
Capsule Endoscopy (Camera Pill) – least common
![Page 11: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/11.jpg)
How is Celiac Disease diagnosed?
Endoscopy and Biopsy
Normal
Celiac
American Academy of Family Physicians www.aafp.org
![Page 12: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/12.jpg)
When is Celiac Disease diagnosed?
Elevated anti-tissue transglutaminase antibodies (tTGA) or anti-endomysium antibodies (EMA) via blood test
Damaged villi (villous atrophy) via biopsy
Celiac Disease can be diagnosed at any age
The longer Celiac Disease goes undiagnosed, risk increases for complications
![Page 13: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/13.jpg)
Additional complications Deficiencies of
Iron, Folic Acid, B-12, calcium, and fat soluble vitamins
Lactose intolerance
Increased risk of GI cancers
Nervous system disorders
Pancreatic insufficiency
Bone loss
![Page 14: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/14.jpg)
How is Celiac Disease treated? No cure Strict adherence to Gluten-Free(GF) Diet
for life If nutrient deficiencies exist, vitamin
supplements will be needed In severe cases, anti-inflammatory drugs
may be needed to combat intestinal inflammation
New celiac patients should consult with a dietitian about a GF diet plan
![Page 15: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/15.jpg)
What is the GF Diet?Strict Avoidance of all products containing wheat, including wheat bran, wheat germ, semolina, durum, enriched flour, and farina, rye, and barley, including barley malt and malt
While oats are technically gluten-free, they are commonly contaminated with gluten unless tested and labeled as gluten-free oats
![Page 16: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/16.jpg)
What is the GF Diet?Special care must be taken to avoid gluten in soups, seasonings, sauces, snack foods, processed meats, condiments, and beverages.
Some restaurant chains have GF menus available.
![Page 17: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/17.jpg)
Living with Celiac Disease With strict adherence to GF Diet,
intestinal damage can be healed Intestinal healing takes 3 to 6 months in
children Healing will take years in adults If improvement is not seen, diet should
be investigated for hidden sources of gluten
Celiac disease is genetic Long-term follow up is recommended
![Page 18: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/18.jpg)
Sources(2008). Celiac disease (NIH Publication No. 08–4269).
Retrieved from National Digestive Diseases Information Clearinghouse website: http://digestive.niddk.nih.gov/ddiseases/pubs/celiac
(2011). Celiac disease. Retrieved from Mayo Foundation for Medical Education and Research website: http://www.mayoclinic.com/health/celiac-disease/DS00319
Celiac Disease Foundation. (2010). Are You the One? [brochure]. Retrieved from http://www.celiac.org/images/stories/PDF/are-you-the-one.pdf
![Page 19: Celiac disease](https://reader033.fdocuments.in/reader033/viewer/2022051821/56816774550346895ddc6713/html5/thumbnails/19.jpg)
Sources (cont.)Celiac Disease Foundation. (2010). Is Your Child the
One? [brochure]. Retrieved from http://www.celiac.org/images/stories/PDF/is-your-child-the-one.pdf
Presutti, R. J. (2007). Celiac disease. American Family Physician, 76(12), 1795-1802. Retrieved from http://www.aafp.org/afp/2007/1215/p1795.html