CEBMMS Mini-Symposium

in Recognition of the 2016 Lund University Honorary Doctorates

Organized by: Lund University Center of Excellence

in Biological and Medical Mass Spectrometry (CEBMMS)

Thursday May 26th, 2016 Fernströmsalen, BMC

Lund, Sweden

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Mini-Symposium Program

Thursday May 26th 2016, Fernströmsalen BMC, Lund, Sweden

Organized by CEBMMS members:

Thomas Laurell and Johan Malmström

08.30-08.55: Arrival and coffee

08:55-09:00 Welcome Address

09.00-09.45: Takehiko Kitamori (Honorary Doctor Eng. Faculty 2016) “Innovating Microfluidics and Pioneering Nanofluidics” University of Tokyo, Japan

09.45-10.30: Ruedi Aebersold (Honorary Doctor Medical Faculty 2016) “Genotypic Variability and the Quantitative Proteotype” ETH Zurich, Switzerland

10.30-10.55: Jian Liu, University of North Carolina, USA “Developing a chemoenzymatic approach to synthesize carbohydrate-base medicines”

10.55-11.10: Short break

11.10-11.45: Michael MacCoss, University of Washington, USA “Having your Cake and Eating it Too: Methods for Data Independent Acquisition without Compromising Precursor Selectivity”

11.45-12.10: Lars Malmström, University of Zurich, Switzerland “Studying protein-protein interactions by mass spectrometry and modeling”

12.10-12.35: Lukas Käll, KTH - Royal Institute of Technology, Sweden “Clustering Mass Spectra based on Fragment Rarity”

12:35-12:40: Concluding remarks

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Professor Takehiko Kitamori, The University of Tokyo Professor Kitamori is a Professor in the Department of Applied Chemistry. Prior to joining the University of Tokyo in 1989, he was a researcher at Hitachi's Energy Research Lab as a nuclear engineer, and he changed his research field from physics to analytical chemistry during this period. In addition to his research origin Applied Laser Spectrometry for Ultrasensitive Analysis, his present main research areas is the Micro and Extended-nano Fluidics for Chemistry and Biomedical Applications. After serving as Dean of School of Engineering (2010-2011), he was Vice President of the University of Tokyo (2012-2013), and Special Assistant to President (2014), responsible for Internationalization, Human Resource Development, and Safety and Security. Professor Kitamori is recipient of numerous honors for innovative research, including the Japan Society for Analytical Chemistry Award (2009), the IBM Faculty Award (2008), and the Chemical Society of Japan Award for Creative Work (2006). Especially, he was awarded as an International Member of the Swedish Royal Physiographic Society in Lund (2014). He is a member of several academic societies including Royal Society of Chemistry, American Chemical Society, Chemical Society of Japan (Director in 2016-2017) , Japan Society for Analytical Chemistry (Senior-Vice President in 2006-2007). He was a launching member of Chemical and Biological Microsystems Society (Vice President in 2006-2013) and Society for Chemistry and Micro-Nano Systems (President in 2002-2003),

Professor Takehiko Kitamori, The University of Tokyo

Professor Ruedi Aebersold, ETH Zurich Prof. Ruedi Aebersold is one of the pioneers in the field of proteomics. He is known for developing wet lab and computational methods that have found wide application in analytical protein chemistry and proteomics. These include methods to quantify the proteome, statistical and computational methods to determine the error rate in large scale proteomic measurements, targeted mass spectrometry techniques to reproducibly quantify sets of proteins in large sample cohorts and methods to probe the organization of proteins into functional modules. Prof. Dr. Aebersold and his team of researchers use these technologies to determine the effects of genomic variation on the proteome and to determine the link between specific proteome states and (clinical) phenotypes. A specific application of these techniques is the determination of the molecular differences of cells in different states, such as noncancerous versus cancerous cells, and to systematically study how cells respond to external stimuli. The result from such studies are expected to lead to new diagnostic markers for disease and to a more complete understanding of the biochemical processes that control and constitute cell physiology. Professor Aebersold is a native of Switzerland and obtained his Ph.D. in Cellular Biology at the Biocenter of the University of Basel in 1983. Since that time, he was a faculty member of the Universities of Washington and British Columbia, until 2000, when he co-founded the Institute for Systems Biology in Seattle. In 2004, he accepted a position as full professor at the Swiss Federal Institute of Technology (ETH) in Zurich, where in January 2005, his research group became the first integral part of the newly founded Institute of Molecular Systems Biology.

Professor Ruedi Aebersold, Swiss Federal Institute of Technology Zurich